

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 6.78769975 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.36322070 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 5.85072735 |
| 4 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.85072735 |
| 5 | respiratory electron transport chain (GO:0022904) | 5.52163152 |
| 6 | electron transport chain (GO:0022900) | 5.39493763 |
| 7 | protein complex biogenesis (GO:0070271) | 4.75415551 |
| 8 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.73528394 |
| 9 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.73528394 |
| 10 | NADH dehydrogenase complex assembly (GO:0010257) | 4.73528394 |
| 11 | protein-cofactor linkage (GO:0018065) | 4.67144805 |
| 12 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.53255675 |
| 13 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.30555973 |
| 14 | DNA deamination (GO:0045006) | 4.19661084 |
| 15 | termination of RNA polymerase III transcription (GO:0006386) | 4.18800802 |
| 16 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.18800802 |
| 17 | positive regulation of prostaglandin secretion (GO:0032308) | 4.08827332 |
| 18 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.87945102 |
| 19 | chaperone-mediated protein transport (GO:0072321) | 3.80612454 |
| 20 | cotranslational protein targeting to membrane (GO:0006613) | 3.79831112 |
| 21 | cytidine deamination (GO:0009972) | 3.77782019 |
| 22 | cytidine metabolic process (GO:0046087) | 3.77782019 |
| 23 | cytidine catabolic process (GO:0006216) | 3.77782019 |
| 24 | protein targeting to ER (GO:0045047) | 3.74969420 |
| 25 | protein localization to cilium (GO:0061512) | 3.72573404 |
| 26 | ribosomal large subunit biogenesis (GO:0042273) | 3.69308078 |
| 27 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.67821555 |
| 28 | protein localization to endoplasmic reticulum (GO:0070972) | 3.63424244 |
| 29 | regulation of prostaglandin secretion (GO:0032306) | 3.61597191 |
| 30 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.61125580 |
| 31 | viral transcription (GO:0019083) | 3.58811956 |
| 32 | hydrogen ion transmembrane transport (GO:1902600) | 3.53854262 |
| 33 | translational termination (GO:0006415) | 3.41696311 |
| 34 | platelet dense granule organization (GO:0060155) | 3.40819033 |
| 35 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.39557920 |
| 36 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.35948787 |
| 37 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.35763032 |
| 38 | proton transport (GO:0015992) | 3.26386977 |
| 39 | hydrogen transport (GO:0006818) | 3.22011866 |
| 40 | anterograde synaptic vesicle transport (GO:0048490) | 3.19672471 |
| 41 | regulation of cellular respiration (GO:0043457) | 3.14915418 |
| 42 | interleukin-1-mediated signaling pathway (GO:0070498) | 3.12976091 |
| 43 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.12561054 |
| 44 | tryptophan metabolic process (GO:0006568) | 3.03567096 |
| 45 | detection of light stimulus involved in visual perception (GO:0050908) | 3.03054920 |
| 46 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.03054920 |
| 47 | indolalkylamine metabolic process (GO:0006586) | 3.00178258 |
| 48 | oxidative phosphorylation (GO:0006119) | 2.96951557 |
| 49 | positive regulation of transcription regulatory region DNA binding (GO:2000679) | 2.95877097 |
| 50 | positive regulation of osteoclast differentiation (GO:0045672) | 2.95723650 |
| 51 | regulation of oxidative phosphorylation (GO:0002082) | 2.94968467 |
| 52 | inner mitochondrial membrane organization (GO:0007007) | 2.94621108 |
| 53 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.91518865 |
| 54 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.89477407 |
| 55 | purine-containing compound salvage (GO:0043101) | 2.89108296 |
| 56 | translational elongation (GO:0006414) | 2.88130887 |
| 57 | viral protein processing (GO:0019082) | 2.86643780 |
| 58 | mast cell activation (GO:0045576) | 2.84851334 |
| 59 | kynurenine metabolic process (GO:0070189) | 2.84706084 |
| 60 | signal peptide processing (GO:0006465) | 2.84435305 |
| 61 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.83993486 |
| 62 | regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664) | 2.81439986 |
| 63 | protein neddylation (GO:0045116) | 2.79659465 |
| 64 | ATP biosynthetic process (GO:0006754) | 2.78199108 |
| 65 | spliceosomal complex assembly (GO:0000245) | 2.77484001 |
| 66 | one-carbon compound transport (GO:0019755) | 2.76686664 |
| 67 | proteasome assembly (GO:0043248) | 2.74737918 |
| 68 | tryptophan catabolic process (GO:0006569) | 2.74666991 |
| 69 | indole-containing compound catabolic process (GO:0042436) | 2.74666991 |
| 70 | indolalkylamine catabolic process (GO:0046218) | 2.74666991 |
| 71 | mismatch repair (GO:0006298) | 2.73233034 |
| 72 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.69017575 |
| 73 | translation (GO:0006412) | 2.66429475 |
| 74 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.65349864 |
| 75 | translational initiation (GO:0006413) | 2.65208773 |
| 76 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.65135667 |
| 77 | L-fucose catabolic process (GO:0042355) | 2.64079062 |
| 78 | fucose catabolic process (GO:0019317) | 2.64079062 |
| 79 | L-fucose metabolic process (GO:0042354) | 2.64079062 |
| 80 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.63352393 |
| 81 | positive regulation of interleukin-8 secretion (GO:2000484) | 2.62201947 |
| 82 | positive regulation of response to biotic stimulus (GO:0002833) | 2.61434374 |
| 83 | regulation of interleukin-8 secretion (GO:2000482) | 2.61169008 |
| 84 | prenylation (GO:0097354) | 2.60054465 |
| 85 | protein prenylation (GO:0018342) | 2.60054465 |
| 86 | positive regulation of icosanoid secretion (GO:0032305) | 2.58521626 |
| 87 | immunoglobulin mediated immune response (GO:0016064) | 2.58499941 |
| 88 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 2.58022909 |
| 89 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.57807567 |
| 90 | negative regulation of B cell proliferation (GO:0030889) | 2.57144568 |
| 91 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.56714661 |
| 92 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.56714661 |
| 93 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.56714661 |
| 94 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.55265882 |
| 95 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.55265882 |
| 96 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 2.54807039 |
| 97 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.53943648 |
| 98 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.51669161 |
| 99 | positive regulation of mast cell activation (GO:0033005) | 2.51360492 |
| 100 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.50928768 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 4.36654728 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.98948390 |
| 3 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 3.18767452 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.04704323 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.04264756 |
| 6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.00283730 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.72117045 |
| 8 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.67751981 |
| 9 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.47490214 |
| 10 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.28760798 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.28461963 |
| 12 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.24282913 |
| 13 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.21421767 |
| 14 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.11650392 |
| 15 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.06859827 |
| 16 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.03581708 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.02384014 |
| 18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.99075670 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.98686784 |
| 20 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.98172940 |
| 21 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.90019103 |
| 22 | EWS_26573619_Chip-Seq_HEK293_Human | 1.89931055 |
| 23 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.85477145 |
| 24 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.84770349 |
| 25 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.82216275 |
| 26 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.78900980 |
| 27 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.65705928 |
| 28 | FUS_26573619_Chip-Seq_HEK293_Human | 1.61970555 |
| 29 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.61166473 |
| 30 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.56646681 |
| 31 | P300_19829295_ChIP-Seq_ESCs_Human | 1.55963865 |
| 32 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.54492976 |
| 33 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.54395150 |
| 34 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.53339056 |
| 35 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.49933731 |
| 36 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.49933731 |
| 37 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.48376979 |
| 38 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.48286605 |
| 39 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.47223654 |
| 40 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.46771371 |
| 41 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.40525234 |
| 42 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.38508731 |
| 43 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.37900906 |
| 44 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.35513295 |
| 45 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.33499478 |
| 46 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.33443840 |
| 47 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.33101435 |
| 48 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.32294371 |
| 49 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.32147957 |
| 50 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.32147957 |
| 51 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.31940605 |
| 52 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.30184049 |
| 53 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.30031454 |
| 54 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.27568817 |
| 55 | GATA3_26560356_Chip-Seq_TH2_Human | 1.27387945 |
| 56 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.26616916 |
| 57 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.25594545 |
| 58 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.25507448 |
| 59 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.25171313 |
| 60 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.24704628 |
| 61 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.23347892 |
| 62 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.22977620 |
| 63 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.22761369 |
| 64 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.22154282 |
| 65 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.21794134 |
| 66 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.21784258 |
| 67 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.21532756 |
| 68 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.21395123 |
| 69 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.21055566 |
| 70 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.20147547 |
| 71 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.19471502 |
| 72 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.18208091 |
| 73 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.17481489 |
| 74 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.17461769 |
| 75 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.16141654 |
| 76 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.15377706 |
| 77 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.14963729 |
| 78 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.14468041 |
| 79 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.14468041 |
| 80 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.13648717 |
| 81 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.13186370 |
| 82 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.12332260 |
| 83 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.11845139 |
| 84 | AR_20517297_ChIP-Seq_VCAP_Human | 1.11299262 |
| 85 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.10908826 |
| 86 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.10314892 |
| 87 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.08644384 |
| 88 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.08410483 |
| 89 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.06325263 |
| 90 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.04753649 |
| 91 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.04065434 |
| 92 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.03367655 |
| 93 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.02495703 |
| 94 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.01793433 |
| 95 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.01780186 |
| 96 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.01514563 |
| 97 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.01407539 |
| 98 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.00596221 |
| 99 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.99590864 |
| 100 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.98851650 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 4.07112580 |
| 2 | MP0001529_abnormal_vocalization | 3.54862473 |
| 3 | MP0005671_abnormal_response_to | 3.39042774 |
| 4 | MP0003806_abnormal_nucleotide_metabolis | 2.99614127 |
| 5 | MP0004147_increased_porphyrin_level | 2.83023356 |
| 6 | MP0004142_abnormal_muscle_tone | 2.78311830 |
| 7 | MP0003436_decreased_susceptibility_to | 2.42660465 |
| 8 | MP0000569_abnormal_digit_pigmentation | 2.32993839 |
| 9 | MP0009785_altered_susceptibility_to | 2.25945573 |
| 10 | MP0002148_abnormal_hypersensitivity_rea | 2.20948004 |
| 11 | MP0006082_CNS_inflammation | 2.18867062 |
| 12 | MP0002234_abnormal_pharynx_morphology | 2.14514779 |
| 13 | MP0006292_abnormal_olfactory_placode | 2.05694251 |
| 14 | MP0004145_abnormal_muscle_electrophysio | 2.03683868 |
| 15 | MP0002090_abnormal_vision | 2.02881676 |
| 16 | MP0000685_abnormal_immune_system | 2.01809246 |
| 17 | MP0006072_abnormal_retinal_apoptosis | 1.98590214 |
| 18 | MP0008875_abnormal_xenobiotic_pharmacok | 1.96180454 |
| 19 | MP0001790_abnormal_immune_system | 1.93577751 |
| 20 | MP0005387_immune_system_phenotype | 1.93577751 |
| 21 | MP0008872_abnormal_physiological_respon | 1.92204942 |
| 22 | MP0005084_abnormal_gallbladder_morpholo | 1.87894047 |
| 23 | MP0003724_increased_susceptibility_to | 1.80353683 |
| 24 | MP0006036_abnormal_mitochondrial_physio | 1.70339434 |
| 25 | MP0005646_abnormal_pituitary_gland | 1.70052361 |
| 26 | MP0005367_renal/urinary_system_phenotyp | 1.69606476 |
| 27 | MP0000516_abnormal_urinary_system | 1.69606476 |
| 28 | MP0005000_abnormal_immune_tolerance | 1.68385853 |
| 29 | MP0001800_abnormal_humoral_immune | 1.66512232 |
| 30 | MP0001984_abnormal_olfaction | 1.65409764 |
| 31 | MP0001440_abnormal_grooming_behavior | 1.62940737 |
| 32 | MP0005551_abnormal_eye_electrophysiolog | 1.54928522 |
| 33 | MP0002254_reproductive_system_inflammat | 1.54445276 |
| 34 | MP0000372_irregular_coat_pigmentation | 1.54173554 |
| 35 | MP0003186_abnormal_redox_activity | 1.54116541 |
| 36 | MP0002102_abnormal_ear_morphology | 1.50764485 |
| 37 | MP0008789_abnormal_olfactory_epithelium | 1.49132964 |
| 38 | MP0005075_abnormal_melanosome_morpholog | 1.44285335 |
| 39 | MP0005253_abnormal_eye_physiology | 1.38368474 |
| 40 | MP0002837_dystrophic_cardiac_calcinosis | 1.38011301 |
| 41 | MP0009379_abnormal_foot_pigmentation | 1.37847649 |
| 42 | MP0009764_decreased_sensitivity_to | 1.36069779 |
| 43 | MP0000371_diluted_coat_color | 1.35778123 |
| 44 | MP0005645_abnormal_hypothalamus_physiol | 1.31048467 |
| 45 | MP0002452_abnormal_antigen_presenting | 1.30727917 |
| 46 | MP0002095_abnormal_skin_pigmentation | 1.28841468 |
| 47 | MP0001486_abnormal_startle_reflex | 1.25037498 |
| 48 | MP0005379_endocrine/exocrine_gland_phen | 1.24048248 |
| 49 | MP0008058_abnormal_DNA_repair | 1.23034193 |
| 50 | MP0002723_abnormal_immune_serum | 1.21836307 |
| 51 | MP0002876_abnormal_thyroid_physiology | 1.21358057 |
| 52 | MP0002938_white_spotting | 1.20786067 |
| 53 | MP0003137_abnormal_impulse_conducting | 1.20010100 |
| 54 | MP0001968_abnormal_touch/_nociception | 1.17277019 |
| 55 | MP0003172_abnormal_lysosome_physiology | 1.16659338 |
| 56 | MP0003011_delayed_dark_adaptation | 1.15376200 |
| 57 | MP0005408_hypopigmentation | 1.14728195 |
| 58 | MP0005171_absent_coat_pigmentation | 1.13520546 |
| 59 | MP0000647_abnormal_sebaceous_gland | 1.09917362 |
| 60 | MP0001986_abnormal_taste_sensitivity | 1.09803401 |
| 61 | MP0009046_muscle_twitch | 1.09618298 |
| 62 | MP0003567_abnormal_fetal_cardiomyocyte | 1.09153913 |
| 63 | MP0003195_calcinosis | 1.06045615 |
| 64 | MP0006035_abnormal_mitochondrial_morpho | 1.05427397 |
| 65 | MP0004043_abnormal_pH_regulation | 1.01652991 |
| 66 | MP0005636_abnormal_mineral_homeostasis | 1.01424006 |
| 67 | MP0002163_abnormal_gland_morphology | 0.99237059 |
| 68 | MP0001905_abnormal_dopamine_level | 0.97986254 |
| 69 | MP0001819_abnormal_immune_cell | 0.97890325 |
| 70 | MP0005535_abnormal_body_temperature | 0.97646541 |
| 71 | MP0005499_abnormal_olfactory_system | 0.96015625 |
| 72 | MP0005394_taste/olfaction_phenotype | 0.96015625 |
| 73 | MP0002006_tumorigenesis | 0.95035174 |
| 74 | MP0002166_altered_tumor_susceptibility | 0.94470855 |
| 75 | MP0001919_abnormal_reproductive_system | 0.93527052 |
| 76 | MP0002420_abnormal_adaptive_immunity | 0.91857334 |
| 77 | MP0008469_abnormal_protein_level | 0.91516395 |
| 78 | MP0009333_abnormal_splenocyte_physiolog | 0.90867612 |
| 79 | MP0001485_abnormal_pinna_reflex | 0.88935602 |
| 80 | MP0001873_stomach_inflammation | 0.88774254 |
| 81 | MP0000639_abnormal_adrenal_gland | 0.86484311 |
| 82 | MP0002075_abnormal_coat/hair_pigmentati | 0.86191004 |
| 83 | MP0000427_abnormal_hair_cycle | 0.85012038 |
| 84 | MP0005025_abnormal_response_to | 0.83999162 |
| 85 | MP0002419_abnormal_innate_immunity | 0.82865722 |
| 86 | MP0005187_abnormal_penis_morphology | 0.81760840 |
| 87 | MP0001186_pigmentation_phenotype | 0.76850220 |
| 88 | MP0001845_abnormal_inflammatory_respons | 0.75909740 |
| 89 | MP0005503_abnormal_tendon_morphology | 0.75267899 |
| 90 | MP0002272_abnormal_nervous_system | 0.74095976 |
| 91 | MP0005670_abnormal_white_adipose | 0.73675316 |
| 92 | MP0001533_abnormal_skeleton_physiology | 0.72251349 |
| 93 | MP0001756_abnormal_urination | 0.71303668 |
| 94 | MP0009745_abnormal_behavioral_response | 0.69229834 |
| 95 | MP0010155_abnormal_intestine_physiology | 0.68672190 |
| 96 | MP0004742_abnormal_vestibular_system | 0.68621758 |
| 97 | MP0000230_abnormal_systemic_arterial | 0.68188025 |
| 98 | MP0005167_abnormal_blood-brain_barrier | 0.67674641 |
| 99 | MP0000716_abnormal_immune_system | 0.67600463 |
| 100 | MP0008873_increased_physiological_sensi | 0.67138192 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hepatocellular necrosis (HP:0001404) | 6.64526482 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 6.45024027 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.64889108 |
| 4 | Mitochondrial inheritance (HP:0001427) | 5.52585244 |
| 5 | Hepatic necrosis (HP:0002605) | 5.47940504 |
| 6 | Progressive macrocephaly (HP:0004481) | 5.39470064 |
| 7 | Acute encephalopathy (HP:0006846) | 5.17291900 |
| 8 | Congenital, generalized hypertrichosis (HP:0004540) | 5.12379850 |
| 9 | Increased CSF lactate (HP:0002490) | 4.64834218 |
| 10 | Increased hepatocellular lipid droplets (HP:0006565) | 4.11075718 |
| 11 | Cerebral edema (HP:0002181) | 4.10226233 |
| 12 | 3-Methylglutaconic aciduria (HP:0003535) | 3.83020711 |
| 13 | Lipid accumulation in hepatocytes (HP:0006561) | 3.82639020 |
| 14 | Leukodystrophy (HP:0002415) | 3.80920418 |
| 15 | Hypothermia (HP:0002045) | 3.46962298 |
| 16 | Multiple enchondromatosis (HP:0005701) | 3.39746395 |
| 17 | Renal Fanconi syndrome (HP:0001994) | 3.36116864 |
| 18 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.26021452 |
| 19 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.26021452 |
| 20 | Exertional dyspnea (HP:0002875) | 3.23143730 |
| 21 | Optic disc pallor (HP:0000543) | 3.14083219 |
| 22 | Hypoproteinemia (HP:0003075) | 3.01508742 |
| 23 | Respiratory failure (HP:0002878) | 2.89191662 |
| 24 | CNS demyelination (HP:0007305) | 2.84818553 |
| 25 | Chronic diarrhea (HP:0002028) | 2.72241309 |
| 26 | Abnormality of the prostate (HP:0008775) | 2.55133351 |
| 27 | Split foot (HP:0001839) | 2.54035990 |
| 28 | Obstructive lung disease (HP:0006536) | 2.53731189 |
| 29 | Chronic obstructive pulmonary disease (HP:0006510) | 2.53731189 |
| 30 | Increased intramyocellular lipid droplets (HP:0012240) | 2.49792135 |
| 31 | Lactic acidosis (HP:0003128) | 2.42736921 |
| 32 | Abnormality of renal resorption (HP:0011038) | 2.42006161 |
| 33 | Absent hand (HP:0004050) | 2.39590442 |
| 34 | Cerebellar dysplasia (HP:0007033) | 2.39196368 |
| 35 | Cleft eyelid (HP:0000625) | 2.37013339 |
| 36 | Global brain atrophy (HP:0002283) | 2.35125734 |
| 37 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.34157299 |
| 38 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.32681665 |
| 39 | Recurrent cutaneous fungal infections (HP:0011370) | 2.32681665 |
| 40 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.30773572 |
| 41 | Type II lissencephaly (HP:0007260) | 2.30355579 |
| 42 | Increased serum lactate (HP:0002151) | 2.27291510 |
| 43 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.23059113 |
| 44 | Aplastic anemia (HP:0001915) | 2.22079790 |
| 45 | Rectovaginal fistula (HP:0000143) | 2.21190299 |
| 46 | Rectal fistula (HP:0100590) | 2.21190299 |
| 47 | Pancreatic cysts (HP:0001737) | 2.17532503 |
| 48 | Abolished electroretinogram (ERG) (HP:0000550) | 2.16492756 |
| 49 | Pulmonary fibrosis (HP:0002206) | 2.15344237 |
| 50 | Woolly hair (HP:0002224) | 2.14640509 |
| 51 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.11204915 |
| 52 | Abnormality of midbrain morphology (HP:0002418) | 2.08876887 |
| 53 | Molar tooth sign on MRI (HP:0002419) | 2.08876887 |
| 54 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.08534706 |
| 55 | Increased muscle lipid content (HP:0009058) | 2.06314968 |
| 56 | Abnormality of lateral ventricle (HP:0030047) | 2.06295663 |
| 57 | Exercise intolerance (HP:0003546) | 2.05149701 |
| 58 | Blindness (HP:0000618) | 2.04535862 |
| 59 | Hemoptysis (HP:0002105) | 2.04216621 |
| 60 | Stomatitis (HP:0010280) | 2.03739001 |
| 61 | Chest pain (HP:0100749) | 2.00895456 |
| 62 | Emotional lability (HP:0000712) | 2.00368075 |
| 63 | Concave nail (HP:0001598) | 1.99124381 |
| 64 | Medial flaring of the eyebrow (HP:0010747) | 1.97648712 |
| 65 | Ureteral obstruction (HP:0006000) | 1.95552067 |
| 66 | Attenuation of retinal blood vessels (HP:0007843) | 1.95442237 |
| 67 | Pruritus (HP:0000989) | 1.93367642 |
| 68 | Premature loss of primary teeth (HP:0006323) | 1.91117478 |
| 69 | Respiratory difficulties (HP:0002880) | 1.90791125 |
| 70 | Nephronophthisis (HP:0000090) | 1.90480410 |
| 71 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.89891063 |
| 72 | X-linked dominant inheritance (HP:0001423) | 1.88794432 |
| 73 | Pulmonary infiltrates (HP:0002113) | 1.88229285 |
| 74 | IgG deficiency (HP:0004315) | 1.87885941 |
| 75 | Abnormality of the renal cortex (HP:0011035) | 1.87712160 |
| 76 | Agammaglobulinemia (HP:0004432) | 1.87216702 |
| 77 | Abnormality of the renal medulla (HP:0100957) | 1.86875405 |
| 78 | Abnormality of the anterior horn cell (HP:0006802) | 1.82131133 |
| 79 | Degeneration of anterior horn cells (HP:0002398) | 1.82131133 |
| 80 | Lethargy (HP:0001254) | 1.81794758 |
| 81 | Amaurosis fugax (HP:0100576) | 1.79541556 |
| 82 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.75871345 |
| 83 | Decreased central vision (HP:0007663) | 1.75445608 |
| 84 | Increased cerebral lipofuscin (HP:0011813) | 1.73927131 |
| 85 | Vaginal fistula (HP:0004320) | 1.73272786 |
| 86 | Abnormality of the pleura (HP:0002103) | 1.72503461 |
| 87 | Congenital stationary night blindness (HP:0007642) | 1.71904818 |
| 88 | Parakeratosis (HP:0001036) | 1.71551795 |
| 89 | Septate vagina (HP:0001153) | 1.69405007 |
| 90 | Hypoplasia of the pons (HP:0012110) | 1.68085662 |
| 91 | Abnormality of the pons (HP:0007361) | 1.66580768 |
| 92 | Amniotic constriction ring (HP:0009775) | 1.63843608 |
| 93 | Abnormality of placental membranes (HP:0011409) | 1.63843608 |
| 94 | Intestinal fistula (HP:0100819) | 1.62654439 |
| 95 | Meningitis (HP:0001287) | 1.61208728 |
| 96 | Periodontitis (HP:0000704) | 1.59113618 |
| 97 | Cerebral palsy (HP:0100021) | 1.57814704 |
| 98 | Ureteral stenosis (HP:0000071) | 1.57461342 |
| 99 | Hyperglycinemia (HP:0002154) | 1.56590467 |
| 100 | Delayed CNS myelination (HP:0002188) | 1.55493048 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K12 | 5.08108559 |
| 2 | BMPR2 | 3.53017737 |
| 3 | MST4 | 3.14081961 |
| 4 | MAP3K13 | 2.88425537 |
| 5 | MAP4K2 | 2.62063331 |
| 6 | TLK1 | 2.59965210 |
| 7 | STK38L | 2.51303393 |
| 8 | VRK2 | 2.50610821 |
| 9 | MYLK | 2.27817457 |
| 10 | CDK19 | 1.99960516 |
| 11 | FRK | 1.97076199 |
| 12 | SRPK1 | 1.93335442 |
| 13 | MAP3K14 | 1.91613325 |
| 14 | TAOK3 | 1.80975048 |
| 15 | TXK | 1.78863517 |
| 16 | ADRBK2 | 1.69856843 |
| 17 | MAP3K4 | 1.53935135 |
| 18 | CSF1R | 1.41323617 |
| 19 | ILK | 1.39795738 |
| 20 | ZAK | 1.39638766 |
| 21 | INSRR | 1.39337754 |
| 22 | DAPK1 | 1.32651958 |
| 23 | CDK3 | 1.32142927 |
| 24 | VRK1 | 1.28002992 |
| 25 | NUAK1 | 1.25442623 |
| 26 | STK24 | 1.23144938 |
| 27 | RPS6KA4 | 1.20217694 |
| 28 | CSNK1G3 | 1.19853143 |
| 29 | OBSCN | 1.17592738 |
| 30 | IKBKB | 1.17236172 |
| 31 | GRK1 | 1.15950488 |
| 32 | ERBB3 | 1.15661243 |
| 33 | MKNK1 | 1.13842455 |
| 34 | MAP4K1 | 1.13360417 |
| 35 | CSNK1A1L | 1.13027353 |
| 36 | FLT3 | 1.10216067 |
| 37 | PHKG2 | 1.07738145 |
| 38 | PHKG1 | 1.07738145 |
| 39 | MKNK2 | 1.06922064 |
| 40 | CSNK1G2 | 1.06908569 |
| 41 | CDK8 | 1.04731235 |
| 42 | OXSR1 | 1.04610705 |
| 43 | BLK | 1.04363952 |
| 44 | WNK4 | 1.01862608 |
| 45 | DAPK3 | 0.99360589 |
| 46 | CSNK1G1 | 0.97555037 |
| 47 | KIT | 0.95461981 |
| 48 | MAP2K6 | 0.93292966 |
| 49 | LYN | 0.88830513 |
| 50 | STK3 | 0.86536983 |
| 51 | WNK3 | 0.86086390 |
| 52 | PRKCE | 0.86022449 |
| 53 | PIK3CG | 0.81758417 |
| 54 | TAF1 | 0.77852299 |
| 55 | TIE1 | 0.77711501 |
| 56 | GRK7 | 0.76305568 |
| 57 | TYK2 | 0.75886617 |
| 58 | CCNB1 | 0.73367423 |
| 59 | CSNK2A2 | 0.71858592 |
| 60 | DYRK2 | 0.70255790 |
| 61 | KDR | 0.69748001 |
| 62 | NEK1 | 0.69413973 |
| 63 | SYK | 0.68533993 |
| 64 | BCKDK | 0.68402700 |
| 65 | TNK2 | 0.67245568 |
| 66 | TRPM7 | 0.66966999 |
| 67 | STK39 | 0.64763860 |
| 68 | SCYL2 | 0.63121723 |
| 69 | PINK1 | 0.63023393 |
| 70 | EGFR | 0.61609540 |
| 71 | RPS6KA5 | 0.61334340 |
| 72 | TEC | 0.59252001 |
| 73 | EPHA3 | 0.57575611 |
| 74 | ACVR1B | 0.56808874 |
| 75 | PRKG1 | 0.56397616 |
| 76 | CASK | 0.56087899 |
| 77 | ADRBK1 | 0.54711549 |
| 78 | PIK3CA | 0.53822869 |
| 79 | TRIM28 | 0.52928738 |
| 80 | IGF1R | 0.51533692 |
| 81 | CAMK2A | 0.51202492 |
| 82 | CSNK2A1 | 0.50757456 |
| 83 | PLK3 | 0.50689915 |
| 84 | AURKB | 0.50431626 |
| 85 | CAMK2D | 0.48252422 |
| 86 | CSNK1E | 0.47074764 |
| 87 | MAP2K7 | 0.44226183 |
| 88 | CHUK | 0.43392615 |
| 89 | PNCK | 0.41530489 |
| 90 | MATK | 0.41464650 |
| 91 | PRKACA | 0.41313199 |
| 92 | ATR | 0.41181920 |
| 93 | MAPK13 | 0.39809693 |
| 94 | CLK1 | 0.39803422 |
| 95 | DYRK3 | 0.39622004 |
| 96 | MAP3K7 | 0.39241145 |
| 97 | LCK | 0.38557434 |
| 98 | ATM | 0.38076052 |
| 99 | SGK1 | 0.37595462 |
| 100 | GRK5 | 0.36256134 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 4.69547504 |
| 2 | Graft-versus-host disease_Homo sapiens_hsa05332 | 4.18344548 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.87632597 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 3.59579918 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.42093698 |
| 6 | Protein export_Homo sapiens_hsa03060 | 3.27504777 |
| 7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.20944386 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 3.17874040 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 3.15601428 |
| 10 | Proteasome_Homo sapiens_hsa03050 | 2.75195015 |
| 11 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.71498186 |
| 12 | Ribosome_Homo sapiens_hsa03010 | 2.33908802 |
| 13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.32939742 |
| 14 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.27445439 |
| 15 | Alzheimers disease_Homo sapiens_hsa05010 | 2.27141084 |
| 16 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.16452508 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 2.11465623 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.09924395 |
| 19 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.86862669 |
| 20 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.83048484 |
| 21 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.75506723 |
| 22 | RNA polymerase_Homo sapiens_hsa03020 | 1.71305231 |
| 23 | Viral myocarditis_Homo sapiens_hsa05416 | 1.65978762 |
| 24 | Leishmaniasis_Homo sapiens_hsa05140 | 1.55099115 |
| 25 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.46799491 |
| 26 | Homologous recombination_Homo sapiens_hsa03440 | 1.44482328 |
| 27 | Phototransduction_Homo sapiens_hsa04744 | 1.27394207 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.18628076 |
| 29 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.16244475 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.01131629 |
| 31 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.99288180 |
| 32 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.97251910 |
| 33 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.97038251 |
| 34 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.91626282 |
| 35 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.78927571 |
| 36 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.76422824 |
| 37 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.76268260 |
| 38 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.75796477 |
| 39 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.74857425 |
| 40 | DNA replication_Homo sapiens_hsa03030 | 0.73738317 |
| 41 | RNA transport_Homo sapiens_hsa03013 | 0.70972579 |
| 42 | Spliceosome_Homo sapiens_hsa03040 | 0.69488766 |
| 43 | Basal transcription factors_Homo sapiens_hsa03022 | 0.67864123 |
| 44 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.65650996 |
| 45 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.65522885 |
| 46 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.65492578 |
| 47 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.62905871 |
| 48 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.60951819 |
| 49 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.60591430 |
| 50 | Phagosome_Homo sapiens_hsa04145 | 0.59513251 |
| 51 | Mismatch repair_Homo sapiens_hsa03430 | 0.59321258 |
| 52 | Purine metabolism_Homo sapiens_hsa00230 | 0.57169764 |
| 53 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.56927605 |
| 54 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.54632364 |
| 55 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.52577017 |
| 56 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.50789093 |
| 57 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.50402613 |
| 58 | Tuberculosis_Homo sapiens_hsa05152 | 0.49536181 |
| 59 | Influenza A_Homo sapiens_hsa05164 | 0.49014812 |
| 60 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.46506086 |
| 61 | Olfactory transduction_Homo sapiens_hsa04740 | 0.43856281 |
| 62 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.42920109 |
| 63 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.42033146 |
| 64 | Nicotine addiction_Homo sapiens_hsa05033 | 0.40499417 |
| 65 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.40453016 |
| 66 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.39386368 |
| 67 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.39125659 |
| 68 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.36319380 |
| 69 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.35719863 |
| 70 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.33930455 |
| 71 | Pertussis_Homo sapiens_hsa05133 | 0.32474717 |
| 72 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.31550734 |
| 73 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.30790741 |
| 74 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.30315974 |
| 75 | Legionellosis_Homo sapiens_hsa05134 | 0.29632481 |
| 76 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.29042655 |
| 77 | Base excision repair_Homo sapiens_hsa03410 | 0.28639597 |
| 78 | Metabolic pathways_Homo sapiens_hsa01100 | 0.27890501 |
| 79 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.27015980 |
| 80 | Salmonella infection_Homo sapiens_hsa05132 | 0.27005339 |
| 81 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.26986445 |
| 82 | Peroxisome_Homo sapiens_hsa04146 | 0.23559858 |
| 83 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.22296009 |
| 84 | Salivary secretion_Homo sapiens_hsa04970 | 0.22136255 |
| 85 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.20960337 |
| 86 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.19929159 |
| 87 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.19890521 |
| 88 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.17130948 |
| 89 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.16474310 |
| 90 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.16310975 |
| 91 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.16115150 |
| 92 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.16004633 |
| 93 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.14904630 |
| 94 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.09805030 |
| 95 | GABAergic synapse_Homo sapiens_hsa04727 | 0.08950030 |
| 96 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.08584039 |
| 97 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.08099540 |
| 98 | Mineral absorption_Homo sapiens_hsa04978 | 0.08091810 |
| 99 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.07182322 |
| 100 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.06932981 |

