

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.68236819 |
| 2 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 6.08661047 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.76501043 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.76501043 |
| 5 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.71288029 |
| 6 | regulation of mitochondrial translation (GO:0070129) | 5.53168105 |
| 7 | respiratory electron transport chain (GO:0022904) | 5.35204818 |
| 8 | protein complex biogenesis (GO:0070271) | 5.34202094 |
| 9 | chaperone-mediated protein transport (GO:0072321) | 5.26548569 |
| 10 | electron transport chain (GO:0022900) | 5.22253940 |
| 11 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.96433697 |
| 12 | maturation of 5.8S rRNA (GO:0000460) | 4.87536091 |
| 13 | sequestering of actin monomers (GO:0042989) | 4.68335739 |
| 14 | protein neddylation (GO:0045116) | 4.52881672 |
| 15 | ribosomal small subunit assembly (GO:0000028) | 4.50311046 |
| 16 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 4.43037070 |
| 17 | DNA deamination (GO:0045006) | 4.41649357 |
| 18 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.38968914 |
| 19 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.38968914 |
| 20 | NADH dehydrogenase complex assembly (GO:0010257) | 4.38968914 |
| 21 | cytochrome complex assembly (GO:0017004) | 4.36750252 |
| 22 | RNA localization (GO:0006403) | 4.19940995 |
| 23 | positive regulation of translational initiation (GO:0045948) | 4.16461046 |
| 24 | pseudouridine synthesis (GO:0001522) | 4.13175267 |
| 25 | regulation of activation of Janus kinase activity (GO:0010533) | 4.12105038 |
| 26 | spliceosomal complex assembly (GO:0000245) | 4.07317301 |
| 27 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.04830831 |
| 28 | termination of RNA polymerase III transcription (GO:0006386) | 4.04830831 |
| 29 | rRNA modification (GO:0000154) | 4.03731097 |
| 30 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.03679770 |
| 31 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.97279416 |
| 32 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.97279416 |
| 33 | inner mitochondrial membrane organization (GO:0007007) | 3.95689882 |
| 34 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.94842379 |
| 35 | viral transcription (GO:0019083) | 3.86428308 |
| 36 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.83765648 |
| 37 | translational termination (GO:0006415) | 3.83748176 |
| 38 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.69002700 |
| 39 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 3.67393562 |
| 40 | cotranslational protein targeting to membrane (GO:0006613) | 3.66114034 |
| 41 | hydrogen ion transmembrane transport (GO:1902600) | 3.65679392 |
| 42 | protein targeting to ER (GO:0045047) | 3.60027031 |
| 43 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254) | 3.58638982 |
| 44 | regulation of helicase activity (GO:0051095) | 3.54692033 |
| 45 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.48462537 |
| 46 | respiratory chain complex IV assembly (GO:0008535) | 3.48441121 |
| 47 | cytidine metabolic process (GO:0046087) | 3.47220307 |
| 48 | cytidine catabolic process (GO:0006216) | 3.47220307 |
| 49 | cytidine deamination (GO:0009972) | 3.47220307 |
| 50 | spliceosomal snRNP assembly (GO:0000387) | 3.41022345 |
| 51 | establishment of protein localization to mitochondrion (GO:0072655) | 3.38094736 |
| 52 | protein localization to endoplasmic reticulum (GO:0070972) | 3.37354686 |
| 53 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 3.34585381 |
| 54 | proton transport (GO:0015992) | 3.33527611 |
| 55 | translation (GO:0006412) | 3.32982805 |
| 56 | proteasome assembly (GO:0043248) | 3.32929416 |
| 57 | hydrogen transport (GO:0006818) | 3.26202534 |
| 58 | oxidative phosphorylation (GO:0006119) | 3.25847251 |
| 59 | protein localization to mitochondrion (GO:0070585) | 3.25366269 |
| 60 | ribosomal small subunit biogenesis (GO:0042274) | 3.21965714 |
| 61 | GTP biosynthetic process (GO:0006183) | 3.20320683 |
| 62 | DNA integration (GO:0015074) | 3.20057786 |
| 63 | protein targeting to mitochondrion (GO:0006626) | 3.18582321 |
| 64 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.17066206 |
| 65 | translational elongation (GO:0006414) | 3.16523181 |
| 66 | ATP biosynthetic process (GO:0006754) | 3.16038476 |
| 67 | chromatin remodeling at centromere (GO:0031055) | 3.13160314 |
| 68 | histone mRNA metabolic process (GO:0008334) | 3.13086463 |
| 69 | secretory granule organization (GO:0033363) | 3.12992699 |
| 70 | organelle disassembly (GO:1903008) | 3.12844766 |
| 71 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.11566777 |
| 72 | CENP-A containing nucleosome assembly (GO:0034080) | 3.10831570 |
| 73 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.09006656 |
| 74 | cullin deneddylation (GO:0010388) | 3.07891666 |
| 75 | intracellular protein transmembrane import (GO:0044743) | 3.07314785 |
| 76 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.06881328 |
| 77 | translational initiation (GO:0006413) | 3.01510810 |
| 78 | platelet dense granule organization (GO:0060155) | 3.00978303 |
| 79 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.97246418 |
| 80 | cellular protein complex disassembly (GO:0043624) | 2.91734195 |
| 81 | DNA damage response, detection of DNA damage (GO:0042769) | 2.89949119 |
| 82 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.89784883 |
| 83 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.89002713 |
| 84 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.89002713 |
| 85 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.83591748 |
| 86 | negative regulation of heart rate (GO:0010459) | 2.83083325 |
| 87 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.81430832 |
| 88 | protein deneddylation (GO:0000338) | 2.79599068 |
| 89 | rRNA methylation (GO:0031167) | 2.77783216 |
| 90 | maturation of SSU-rRNA (GO:0030490) | 2.77519184 |
| 91 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.76346307 |
| 92 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.75107446 |
| 93 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.75107446 |
| 94 | regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253) | 2.73719129 |
| 95 | protein peptidyl-prolyl isomerization (GO:0000413) | 2.72319694 |
| 96 | viral life cycle (GO:0019058) | 2.70534960 |
| 97 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.69810992 |
| 98 | mitochondrial transport (GO:0006839) | 2.67926718 |
| 99 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.65667507 |
| 100 | negative regulation of ligase activity (GO:0051352) | 2.64330750 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.04808942 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.91577642 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.83642679 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.44000363 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.18242763 |
| 6 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.76732034 |
| 7 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.69178672 |
| 8 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.62948574 |
| 9 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.57167303 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.52306783 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.46973694 |
| 12 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.39436605 |
| 13 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.35090775 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.34302264 |
| 15 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.27957873 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.27478022 |
| 17 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.22097357 |
| 18 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.21084100 |
| 19 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.18197112 |
| 20 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.15981409 |
| 21 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.14633171 |
| 22 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.09544183 |
| 23 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.07088959 |
| 24 | VDR_22108803_ChIP-Seq_LS180_Human | 2.01704622 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.00246278 |
| 26 | EWS_26573619_Chip-Seq_HEK293_Human | 1.99208493 |
| 27 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.94551140 |
| 28 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.93364146 |
| 29 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.87464715 |
| 30 | FUS_26573619_Chip-Seq_HEK293_Human | 1.87101271 |
| 31 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.75098065 |
| 32 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.71086059 |
| 33 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.67366352 |
| 34 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.65802270 |
| 35 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.60494793 |
| 36 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.59814192 |
| 37 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.59318246 |
| 38 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.53631114 |
| 39 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.51021338 |
| 40 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.47293655 |
| 41 | P300_19829295_ChIP-Seq_ESCs_Human | 1.45645906 |
| 42 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.42069807 |
| 43 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.41052006 |
| 44 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.40621460 |
| 45 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.36302309 |
| 46 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.35660632 |
| 47 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.35212537 |
| 48 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.34538292 |
| 49 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.33245137 |
| 50 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.32538735 |
| 51 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.32355375 |
| 52 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.28922852 |
| 53 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.28553828 |
| 54 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.27768674 |
| 55 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.24610612 |
| 56 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.21786483 |
| 57 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.20413170 |
| 58 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.19603737 |
| 59 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.17752718 |
| 60 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.17354368 |
| 61 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.14273528 |
| 62 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.14272612 |
| 63 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.14017284 |
| 64 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.12194151 |
| 65 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.11721126 |
| 66 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.11349018 |
| 67 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.11115853 |
| 68 | AR_20517297_ChIP-Seq_VCAP_Human | 1.10871959 |
| 69 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.10527864 |
| 70 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.08493005 |
| 71 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.08493005 |
| 72 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.06166791 |
| 73 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.05587772 |
| 74 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.05587772 |
| 75 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.05429929 |
| 76 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.03054750 |
| 77 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.03054750 |
| 78 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.02645350 |
| 79 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.02180818 |
| 80 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.01780114 |
| 81 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.00626722 |
| 82 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.98986665 |
| 83 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.97349595 |
| 84 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.96883357 |
| 85 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.96713289 |
| 86 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.95809868 |
| 87 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.94809240 |
| 88 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.94388409 |
| 89 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.93510922 |
| 90 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.93279549 |
| 91 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.93129629 |
| 92 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.90629781 |
| 93 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.90091294 |
| 94 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.88613055 |
| 95 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.86267845 |
| 96 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.86267845 |
| 97 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.86133951 |
| 98 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.85875708 |
| 99 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.82519841 |
| 100 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.81785102 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.93332092 |
| 2 | MP0009379_abnormal_foot_pigmentation | 3.23281087 |
| 3 | MP0006072_abnormal_retinal_apoptosis | 2.90651315 |
| 4 | MP0001529_abnormal_vocalization | 2.89946714 |
| 5 | MP0005084_abnormal_gallbladder_morpholo | 2.42840936 |
| 6 | MP0002277_abnormal_respiratory_mucosa | 2.15902672 |
| 7 | MP0002102_abnormal_ear_morphology | 2.07332530 |
| 8 | MP0004147_increased_porphyrin_level | 2.03413013 |
| 9 | MP0001188_hyperpigmentation | 1.99428475 |
| 10 | MP0004142_abnormal_muscle_tone | 1.93835916 |
| 11 | MP0000049_abnormal_middle_ear | 1.91344442 |
| 12 | MP0003693_abnormal_embryo_hatching | 1.91182263 |
| 13 | MP0002736_abnormal_nociception_after | 1.89559748 |
| 14 | MP0004145_abnormal_muscle_electrophysio | 1.88477859 |
| 15 | MP0008058_abnormal_DNA_repair | 1.85854200 |
| 16 | MP0005253_abnormal_eye_physiology | 1.76508993 |
| 17 | MP0001984_abnormal_olfaction | 1.76145283 |
| 18 | MP0001968_abnormal_touch/_nociception | 1.71430650 |
| 19 | MP0006035_abnormal_mitochondrial_morpho | 1.71379485 |
| 20 | MP0002234_abnormal_pharynx_morphology | 1.69379022 |
| 21 | MP0003646_muscle_fatigue | 1.69012286 |
| 22 | MP0001293_anophthalmia | 1.67712967 |
| 23 | MP0005645_abnormal_hypothalamus_physiol | 1.63328919 |
| 24 | MP0005671_abnormal_response_to | 1.62123201 |
| 25 | MP0003880_abnormal_central_pattern | 1.59469538 |
| 26 | MP0006276_abnormal_autonomic_nervous | 1.53047161 |
| 27 | MP0006036_abnormal_mitochondrial_physio | 1.52957098 |
| 28 | MP0003122_maternal_imprinting | 1.48695273 |
| 29 | MP0004957_abnormal_blastocyst_morpholog | 1.46779118 |
| 30 | MP0001486_abnormal_startle_reflex | 1.46430672 |
| 31 | MP0000631_abnormal_neuroendocrine_gland | 1.46048482 |
| 32 | MP0008995_early_reproductive_senescence | 1.44986595 |
| 33 | MP0008789_abnormal_olfactory_epithelium | 1.39213535 |
| 34 | MP0005551_abnormal_eye_electrophysiolog | 1.38524563 |
| 35 | MP0003011_delayed_dark_adaptation | 1.38170019 |
| 36 | MP0001919_abnormal_reproductive_system | 1.37979602 |
| 37 | MP0004133_heterotaxia | 1.36764864 |
| 38 | MP0001905_abnormal_dopamine_level | 1.36579527 |
| 39 | MP0008877_abnormal_DNA_methylation | 1.35301993 |
| 40 | MP0009745_abnormal_behavioral_response | 1.34681683 |
| 41 | MP0002272_abnormal_nervous_system | 1.33732714 |
| 42 | MP0003567_abnormal_fetal_cardiomyocyte | 1.33654267 |
| 43 | MP0003787_abnormal_imprinting | 1.32947252 |
| 44 | MP0002837_dystrophic_cardiac_calcinosis | 1.32372089 |
| 45 | MP0003938_abnormal_ear_development | 1.32324912 |
| 46 | MP0003941_abnormal_skin_development | 1.30227707 |
| 47 | MP0002938_white_spotting | 1.29587467 |
| 48 | MP0003121_genomic_imprinting | 1.28713100 |
| 49 | MP0003136_yellow_coat_color | 1.28457814 |
| 50 | MP0003718_maternal_effect | 1.28174718 |
| 51 | MP0003186_abnormal_redox_activity | 1.27294323 |
| 52 | MP0002822_catalepsy | 1.22239889 |
| 53 | MP0001485_abnormal_pinna_reflex | 1.20701883 |
| 54 | MP0008872_abnormal_physiological_respon | 1.19352984 |
| 55 | MP0002751_abnormal_autonomic_nervous | 1.16266188 |
| 56 | MP0005389_reproductive_system_phenotype | 1.15168386 |
| 57 | MP0005410_abnormal_fertilization | 1.13401063 |
| 58 | MP0001286_abnormal_eye_development | 1.10550958 |
| 59 | MP0005394_taste/olfaction_phenotype | 1.10407519 |
| 60 | MP0005499_abnormal_olfactory_system | 1.10407519 |
| 61 | MP0002735_abnormal_chemical_nociception | 1.09722346 |
| 62 | MP0002752_abnormal_somatic_nervous | 1.08670999 |
| 63 | MP0003195_calcinosis | 1.07397694 |
| 64 | MP0008932_abnormal_embryonic_tissue | 1.05768567 |
| 65 | MP0002233_abnormal_nose_morphology | 1.04907250 |
| 66 | MP0002734_abnormal_mechanical_nocicepti | 1.04526054 |
| 67 | MP0000372_irregular_coat_pigmentation | 1.03802134 |
| 68 | MP0009764_decreased_sensitivity_to | 0.99742409 |
| 69 | MP0009046_muscle_twitch | 0.98888103 |
| 70 | MP0003635_abnormal_synaptic_transmissio | 0.95214865 |
| 71 | MP0002653_abnormal_ependyma_morphology | 0.94993307 |
| 72 | MP0009697_abnormal_copulation | 0.94931016 |
| 73 | MP0002572_abnormal_emotion/affect_behav | 0.94535340 |
| 74 | MP0000026_abnormal_inner_ear | 0.93940906 |
| 75 | MP0004885_abnormal_endolymph | 0.92849067 |
| 76 | MP0001970_abnormal_pain_threshold | 0.92533015 |
| 77 | MP0008007_abnormal_cellular_replicative | 0.92531269 |
| 78 | MP0005377_hearing/vestibular/ear_phenot | 0.91950615 |
| 79 | MP0003878_abnormal_ear_physiology | 0.91950615 |
| 80 | MP0003137_abnormal_impulse_conducting | 0.91349579 |
| 81 | MP0010094_abnormal_chromosome_stability | 0.90651967 |
| 82 | MP0005075_abnormal_melanosome_morpholog | 0.89956906 |
| 83 | MP0008875_abnormal_xenobiotic_pharmacok | 0.89328332 |
| 84 | MP0005391_vision/eye_phenotype | 0.88282250 |
| 85 | MP0002638_abnormal_pupillary_reflex | 0.87991163 |
| 86 | MP0003077_abnormal_cell_cycle | 0.87000178 |
| 87 | MP0004742_abnormal_vestibular_system | 0.86044562 |
| 88 | MP0002184_abnormal_innervation | 0.85043009 |
| 89 | MP0005195_abnormal_posterior_eye | 0.84970931 |
| 90 | MP0002160_abnormal_reproductive_system | 0.84739222 |
| 91 | MP0001963_abnormal_hearing_physiology | 0.82640972 |
| 92 | MP0010386_abnormal_urinary_bladder | 0.81575180 |
| 93 | MP0004215_abnormal_myocardial_fiber | 0.81341017 |
| 94 | MP0002090_abnormal_vision | 0.80813260 |
| 95 | MP0002697_abnormal_eye_size | 0.79859345 |
| 96 | MP0002163_abnormal_gland_morphology | 0.79272176 |
| 97 | MP0001835_abnormal_antigen_presentation | 0.76849678 |
| 98 | MP0003937_abnormal_limbs/digits/tail_de | 0.75492148 |
| 99 | MP0000778_abnormal_nervous_system | 0.73120025 |
| 100 | MP0002282_abnormal_trachea_morphology | 0.72748647 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.44102001 |
| 2 | Aplastic anemia (HP:0001915) | 4.90074510 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.76350717 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.71368631 |
| 5 | Increased hepatocellular lipid droplets (HP:0006565) | 4.65486741 |
| 6 | Acute encephalopathy (HP:0006846) | 4.54303843 |
| 7 | Progressive macrocephaly (HP:0004481) | 4.52218568 |
| 8 | Lipid accumulation in hepatocytes (HP:0006561) | 4.35670116 |
| 9 | Increased CSF lactate (HP:0002490) | 4.02802103 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.97739866 |
| 11 | Oral leukoplakia (HP:0002745) | 3.81754680 |
| 12 | Renal Fanconi syndrome (HP:0001994) | 3.52179538 |
| 13 | Cerebral edema (HP:0002181) | 3.46769602 |
| 14 | Hepatic necrosis (HP:0002605) | 3.46341711 |
| 15 | Increased intramyocellular lipid droplets (HP:0012240) | 3.24140955 |
| 16 | 3-Methylglutaconic aciduria (HP:0003535) | 3.20182163 |
| 17 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.16484667 |
| 18 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.16484667 |
| 19 | Methylmalonic acidemia (HP:0002912) | 3.05599590 |
| 20 | Pancreatic cysts (HP:0001737) | 3.01992528 |
| 21 | True hermaphroditism (HP:0010459) | 2.97544888 |
| 22 | Septo-optic dysplasia (HP:0100842) | 2.97113987 |
| 23 | Exertional dyspnea (HP:0002875) | 2.89009136 |
| 24 | Pancreatic fibrosis (HP:0100732) | 2.83278568 |
| 25 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.78329291 |
| 26 | Colon cancer (HP:0003003) | 2.74056667 |
| 27 | Abnormal number of erythroid precursors (HP:0012131) | 2.69738801 |
| 28 | Increased muscle lipid content (HP:0009058) | 2.69638292 |
| 29 | Leukodystrophy (HP:0002415) | 2.68735639 |
| 30 | Macrocytic anemia (HP:0001972) | 2.65896560 |
| 31 | Congenital, generalized hypertrichosis (HP:0004540) | 2.57815683 |
| 32 | Abnormality of midbrain morphology (HP:0002418) | 2.54418737 |
| 33 | Molar tooth sign on MRI (HP:0002419) | 2.54418737 |
| 34 | Nephronophthisis (HP:0000090) | 2.53148768 |
| 35 | Optic disc pallor (HP:0000543) | 2.46892946 |
| 36 | Lactic acidosis (HP:0003128) | 2.43010776 |
| 37 | Respiratory failure (HP:0002878) | 2.42489937 |
| 38 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.37076079 |
| 39 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.35944017 |
| 40 | Increased serum lactate (HP:0002151) | 2.35383730 |
| 41 | Methylmalonic aciduria (HP:0012120) | 2.31473943 |
| 42 | Lethargy (HP:0001254) | 2.28966235 |
| 43 | Short tibia (HP:0005736) | 2.26904435 |
| 44 | Respiratory difficulties (HP:0002880) | 2.24556997 |
| 45 | Exercise intolerance (HP:0003546) | 2.23448463 |
| 46 | Abnormality of renal resorption (HP:0011038) | 2.22270296 |
| 47 | Cerebral hypomyelination (HP:0006808) | 2.21505525 |
| 48 | Sclerocornea (HP:0000647) | 2.19722162 |
| 49 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.14754993 |
| 50 | Medial flaring of the eyebrow (HP:0010747) | 2.13140168 |
| 51 | Type 2 muscle fiber atrophy (HP:0003554) | 2.08445056 |
| 52 | Absent septum pellucidum (HP:0001331) | 2.04910969 |
| 53 | CNS demyelination (HP:0007305) | 2.03611835 |
| 54 | Fibular aplasia (HP:0002990) | 2.03253987 |
| 55 | Growth hormone deficiency (HP:0000824) | 2.02555458 |
| 56 | Abnormality of the septum pellucidum (HP:0007375) | 2.02273275 |
| 57 | Pendular nystagmus (HP:0012043) | 2.00557206 |
| 58 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.94287652 |
| 59 | Gait imbalance (HP:0002141) | 1.94021882 |
| 60 | Glycosuria (HP:0003076) | 1.92646927 |
| 61 | Abnormality of urine glucose concentration (HP:0011016) | 1.92646927 |
| 62 | Abnormality of the renal medulla (HP:0100957) | 1.92023812 |
| 63 | Muscle fiber atrophy (HP:0100295) | 1.91618992 |
| 64 | Hyperglycinemia (HP:0002154) | 1.91188120 |
| 65 | Congenital primary aphakia (HP:0007707) | 1.89848502 |
| 66 | Constricted visual fields (HP:0001133) | 1.89784961 |
| 67 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.89419979 |
| 68 | Pallor (HP:0000980) | 1.89143812 |
| 69 | Concave nail (HP:0001598) | 1.88754259 |
| 70 | Abnormality of serum amino acid levels (HP:0003112) | 1.85347711 |
| 71 | Hyperphosphaturia (HP:0003109) | 1.83234044 |
| 72 | Carpal bone hypoplasia (HP:0001498) | 1.82067824 |
| 73 | Male pseudohermaphroditism (HP:0000037) | 1.79692035 |
| 74 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.79084641 |
| 75 | Pancytopenia (HP:0001876) | 1.78567718 |
| 76 | Homocystinuria (HP:0002156) | 1.78085650 |
| 77 | Abnormality of homocysteine metabolism (HP:0010919) | 1.78085650 |
| 78 | Optic nerve hypoplasia (HP:0000609) | 1.77668323 |
| 79 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.76636965 |
| 80 | Medulloblastoma (HP:0002885) | 1.75432549 |
| 81 | Anencephaly (HP:0002323) | 1.74812279 |
| 82 | Decreased central vision (HP:0007663) | 1.72766041 |
| 83 | Abolished electroretinogram (ERG) (HP:0000550) | 1.72398278 |
| 84 | Abnormality of vitamin B metabolism (HP:0004340) | 1.72029877 |
| 85 | Renal cortical cysts (HP:0000803) | 1.71562960 |
| 86 | Cellular immunodeficiency (HP:0005374) | 1.69192699 |
| 87 | Nephrogenic diabetes insipidus (HP:0009806) | 1.68998827 |
| 88 | Abnormality of alanine metabolism (HP:0010916) | 1.68802929 |
| 89 | Hyperalaninemia (HP:0003348) | 1.68802929 |
| 90 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.68802929 |
| 91 | Generalized aminoaciduria (HP:0002909) | 1.68520538 |
| 92 | Abnormal ciliary motility (HP:0012262) | 1.68233474 |
| 93 | Supernumerary spleens (HP:0009799) | 1.67480801 |
| 94 | Megaloblastic anemia (HP:0001889) | 1.66153922 |
| 95 | Abnormal lung lobation (HP:0002101) | 1.65884961 |
| 96 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.65841420 |
| 97 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.65841420 |
| 98 | Emotional lability (HP:0000712) | 1.64947966 |
| 99 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.63198384 |
| 100 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.61863076 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 3.76932643 |
| 2 | VRK2 | 2.97263978 |
| 3 | RIPK1 | 2.87315729 |
| 4 | MAP3K4 | 2.65565252 |
| 5 | CDC7 | 2.56382281 |
| 6 | MAP2K7 | 2.48711033 |
| 7 | VRK1 | 2.46588006 |
| 8 | CDK19 | 2.37918212 |
| 9 | INSRR | 2.35674848 |
| 10 | SRPK1 | 2.34226244 |
| 11 | ZAK | 2.28253882 |
| 12 | WNK3 | 2.21364364 |
| 13 | BCR | 2.19160821 |
| 14 | DYRK2 | 2.16480015 |
| 15 | TXK | 1.91045416 |
| 16 | BMPR2 | 1.88441303 |
| 17 | MST4 | 1.84701322 |
| 18 | NME1 | 1.83154482 |
| 19 | TRIM28 | 1.74181407 |
| 20 | BUB1 | 1.73934556 |
| 21 | TLK1 | 1.70604637 |
| 22 | STK16 | 1.70501417 |
| 23 | NUAK1 | 1.61715125 |
| 24 | DYRK3 | 1.52176980 |
| 25 | ADRBK2 | 1.51504957 |
| 26 | TSSK6 | 1.50045767 |
| 27 | MAP3K12 | 1.43506009 |
| 28 | KDR | 1.43344561 |
| 29 | MAPK13 | 1.33123941 |
| 30 | BCKDK | 1.32132577 |
| 31 | NEK1 | 1.28792566 |
| 32 | PBK | 1.27227484 |
| 33 | OXSR1 | 1.18417750 |
| 34 | PLK3 | 1.17965505 |
| 35 | PRKCG | 1.15686912 |
| 36 | CSNK1G3 | 1.13849201 |
| 37 | PRKCI | 1.13229275 |
| 38 | CSNK1G1 | 1.11966418 |
| 39 | MKNK1 | 1.10912108 |
| 40 | GRK1 | 1.09244840 |
| 41 | CSNK1G2 | 1.04632939 |
| 42 | PRKCE | 0.96822894 |
| 43 | MAPK15 | 0.95829690 |
| 44 | CSNK1A1L | 0.95273194 |
| 45 | DAPK3 | 0.93111387 |
| 46 | TNIK | 0.92983567 |
| 47 | BMPR1B | 0.92654009 |
| 48 | PLK4 | 0.90021009 |
| 49 | UHMK1 | 0.88423910 |
| 50 | EIF2AK3 | 0.88147738 |
| 51 | TAF1 | 0.81282079 |
| 52 | MAP2K4 | 0.80086622 |
| 53 | PINK1 | 0.75229845 |
| 54 | RPS6KA5 | 0.74161144 |
| 55 | MKNK2 | 0.73877495 |
| 56 | MAP4K1 | 0.73849803 |
| 57 | PNCK | 0.73842189 |
| 58 | MARK1 | 0.72562680 |
| 59 | BLK | 0.72300355 |
| 60 | TIE1 | 0.71588733 |
| 61 | CASK | 0.68391074 |
| 62 | ERBB3 | 0.68100252 |
| 63 | AURKB | 0.64053022 |
| 64 | STK4 | 0.61885935 |
| 65 | CSNK2A1 | 0.60925804 |
| 66 | PLK1 | 0.59486138 |
| 67 | OBSCN | 0.58898258 |
| 68 | CSNK2A2 | 0.58004644 |
| 69 | PAK4 | 0.57555214 |
| 70 | EIF2AK2 | 0.57361849 |
| 71 | TAOK3 | 0.55157734 |
| 72 | RPS6KA4 | 0.53684540 |
| 73 | CAMKK2 | 0.53422267 |
| 74 | CSNK1A1 | 0.49712765 |
| 75 | PKN1 | 0.48390434 |
| 76 | CAMK2A | 0.47668915 |
| 77 | TAOK1 | 0.47196222 |
| 78 | GRK6 | 0.46325439 |
| 79 | GRK7 | 0.45306637 |
| 80 | PIM1 | 0.44657423 |
| 81 | STK38L | 0.44584710 |
| 82 | BRSK2 | 0.44455608 |
| 83 | CDK3 | 0.42439329 |
| 84 | NEK2 | 0.38917765 |
| 85 | PDK2 | 0.38714775 |
| 86 | DYRK1B | 0.38613259 |
| 87 | CHEK2 | 0.38323310 |
| 88 | MINK1 | 0.36225269 |
| 89 | PLK2 | 0.35587275 |
| 90 | FRK | 0.34169374 |
| 91 | PRKG1 | 0.33834087 |
| 92 | PRKACA | 0.33739132 |
| 93 | CDK8 | 0.33691690 |
| 94 | CAMK1 | 0.33277023 |
| 95 | ATR | 0.33263512 |
| 96 | WEE1 | 0.32732867 |
| 97 | WNK4 | 0.32296322 |
| 98 | MYLK | 0.31866462 |
| 99 | DAPK1 | 0.31118215 |
| 100 | SYK | 0.30330602 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.81603189 |
| 2 | Parkinsons disease_Homo sapiens_hsa05012 | 4.10691093 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 4.09186367 |
| 4 | Protein export_Homo sapiens_hsa03060 | 3.59390607 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 3.59052178 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.99898892 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.94822331 |
| 8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.62829095 |
| 9 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.44824692 |
| 10 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.35815211 |
| 11 | Spliceosome_Homo sapiens_hsa03040 | 2.21374153 |
| 12 | Mismatch repair_Homo sapiens_hsa03430 | 2.03225636 |
| 13 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.97077876 |
| 14 | RNA degradation_Homo sapiens_hsa03018 | 1.88905199 |
| 15 | Asthma_Homo sapiens_hsa05310 | 1.84786860 |
| 16 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.80302953 |
| 17 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.75450237 |
| 18 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.63890720 |
| 19 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.62587902 |
| 20 | Homologous recombination_Homo sapiens_hsa03440 | 1.60557943 |
| 21 | Allograft rejection_Homo sapiens_hsa05330 | 1.50345735 |
| 22 | Nicotine addiction_Homo sapiens_hsa05033 | 1.44008080 |
| 23 | DNA replication_Homo sapiens_hsa03030 | 1.43360574 |
| 24 | RNA transport_Homo sapiens_hsa03013 | 1.42380284 |
| 25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.36758728 |
| 26 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.29681149 |
| 27 | Basal transcription factors_Homo sapiens_hsa03022 | 1.26170606 |
| 28 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.23949443 |
| 29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.23946170 |
| 30 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.23384051 |
| 31 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.13473471 |
| 32 | Phototransduction_Homo sapiens_hsa04744 | 1.13171487 |
| 33 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.10519982 |
| 34 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.05804219 |
| 35 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.05329675 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.03725212 |
| 37 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.01863061 |
| 38 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.96166250 |
| 39 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.94067688 |
| 40 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.92627944 |
| 41 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.91787282 |
| 42 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.90630525 |
| 43 | Olfactory transduction_Homo sapiens_hsa04740 | 0.81394462 |
| 44 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.79965159 |
| 45 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.79666233 |
| 46 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.77839973 |
| 47 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.74977145 |
| 48 | Taste transduction_Homo sapiens_hsa04742 | 0.71889405 |
| 49 | Peroxisome_Homo sapiens_hsa04146 | 0.70318353 |
| 50 | Base excision repair_Homo sapiens_hsa03410 | 0.70117476 |
| 51 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.67349368 |
| 52 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.66942967 |
| 53 | GABAergic synapse_Homo sapiens_hsa04727 | 0.65223055 |
| 54 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.62685878 |
| 55 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.62622663 |
| 56 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.62387366 |
| 57 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.62014207 |
| 58 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.61564276 |
| 59 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.61542176 |
| 60 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.60361045 |
| 61 | Morphine addiction_Homo sapiens_hsa05032 | 0.59089967 |
| 62 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.57874885 |
| 63 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.57850137 |
| 64 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.57693309 |
| 65 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.56030758 |
| 66 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.55944688 |
| 67 | Metabolic pathways_Homo sapiens_hsa01100 | 0.55611591 |
| 68 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.55480217 |
| 69 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.53964350 |
| 70 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.49989601 |
| 71 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.49947378 |
| 72 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.48176741 |
| 73 | Alcoholism_Homo sapiens_hsa05034 | 0.46898970 |
| 74 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.46622504 |
| 75 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.46536252 |
| 76 | Sulfur relay system_Homo sapiens_hsa04122 | 0.45902769 |
| 77 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.43708667 |
| 78 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.43140857 |
| 79 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.42507294 |
| 80 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.42119527 |
| 81 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.40456687 |
| 82 | Retinol metabolism_Homo sapiens_hsa00830 | 0.40365296 |
| 83 | Viral myocarditis_Homo sapiens_hsa05416 | 0.37617405 |
| 84 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.34257456 |
| 85 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.33418716 |
| 86 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.32703449 |
| 87 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.30248496 |
| 88 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.30172987 |
| 89 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.29573604 |
| 90 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.29293917 |
| 91 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.26145097 |
| 92 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.26021264 |
| 93 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.25404080 |
| 94 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.25380641 |
| 95 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.23838727 |
| 96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.23138877 |
| 97 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.20828389 |
| 98 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.19639653 |
| 99 | Cell cycle_Homo sapiens_hsa04110 | 0.19573822 |
| 100 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.17656147 |

