Rank | Gene Set | Z-score |
---|---|---|
1 | nuclear pore complex assembly (GO:0051292) | 6.09925323 |
2 | DNA unwinding involved in DNA replication (GO:0006268) | 5.75775635 |
3 | nuclear pore organization (GO:0006999) | 5.48976418 |
4 | DNA strand elongation involved in DNA replication (GO:0006271) | 5.25103194 |
5 | mitotic sister chromatid cohesion (GO:0007064) | 5.22422899 |
6 | establishment of integrated proviral latency (GO:0075713) | 5.10506696 |
7 | DNA strand elongation (GO:0022616) | 5.04629826 |
8 | protein localization to kinetochore (GO:0034501) | 4.83927267 |
9 | mitotic sister chromatid segregation (GO:0000070) | 4.74464481 |
10 | mitotic chromosome condensation (GO:0007076) | 4.71466710 |
11 | sister chromatid segregation (GO:0000819) | 4.69090451 |
12 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.66046807 |
13 | mitotic metaphase plate congression (GO:0007080) | 4.49901985 |
14 | protein localization to chromosome, centromeric region (GO:0071459) | 4.46662636 |
15 | pore complex assembly (GO:0046931) | 4.45911859 |
16 | DNA replication initiation (GO:0006270) | 4.41801878 |
17 | DNA replication checkpoint (GO:0000076) | 4.09511046 |
18 | telomere maintenance via recombination (GO:0000722) | 4.06505258 |
19 | chromatin remodeling at centromere (GO:0031055) | 4.05826392 |
20 | mitotic nuclear envelope disassembly (GO:0007077) | 4.04914735 |
21 | IMP biosynthetic process (GO:0006188) | 4.02232778 |
22 | mitotic recombination (GO:0006312) | 4.02047219 |
23 | CENP-A containing nucleosome assembly (GO:0034080) | 4.01414347 |
24 | DNA topological change (GO:0006265) | 4.01400298 |
25 | regulation of centriole replication (GO:0046599) | 3.93426568 |
26 | metaphase plate congression (GO:0051310) | 3.93144953 |
27 | ribosome assembly (GO:0042255) | 3.91440300 |
28 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.89319852 |
29 | non-recombinational repair (GO:0000726) | 3.88960452 |
30 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.88960452 |
31 | nuclear envelope disassembly (GO:0051081) | 3.80176954 |
32 | membrane disassembly (GO:0030397) | 3.80176954 |
33 | DNA ligation (GO:0006266) | 3.74847124 |
34 | establishment of viral latency (GO:0019043) | 3.74394514 |
35 | DNA duplex unwinding (GO:0032508) | 3.73437652 |
36 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.68399400 |
37 | heterochromatin organization (GO:0070828) | 3.67014163 |
38 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.66050814 |
39 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.66050814 |
40 | DNA geometric change (GO:0032392) | 3.65753024 |
41 | positive regulation of chromosome segregation (GO:0051984) | 3.63848847 |
42 | DNA replication-independent nucleosome organization (GO:0034724) | 3.61694641 |
43 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.61694641 |
44 | IMP metabolic process (GO:0046040) | 3.61459154 |
45 | purine nucleobase biosynthetic process (GO:0009113) | 3.58362826 |
46 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.55017650 |
47 | regulation of chromosome segregation (GO:0051983) | 3.52223836 |
48 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.51982820 |
49 | spindle checkpoint (GO:0031577) | 3.51950383 |
50 | kinetochore organization (GO:0051383) | 3.49340080 |
51 | histone exchange (GO:0043486) | 3.48132874 |
52 | nucleobase biosynthetic process (GO:0046112) | 3.47984868 |
53 | regulation of DNA endoreduplication (GO:0032875) | 3.46799413 |
54 | regulation of sister chromatid cohesion (GO:0007063) | 3.46447952 |
55 | negative regulation of mRNA processing (GO:0050686) | 3.46369700 |
56 | negative regulation of chromosome segregation (GO:0051985) | 3.45546514 |
57 | mitotic spindle checkpoint (GO:0071174) | 3.44938182 |
58 | meiotic chromosome segregation (GO:0045132) | 3.41902720 |
59 | formation of translation preinitiation complex (GO:0001731) | 3.39491840 |
60 | ATP-dependent chromatin remodeling (GO:0043044) | 3.38405986 |
61 | establishment of chromosome localization (GO:0051303) | 3.37711157 |
62 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.36898961 |
63 | negative regulation of sister chromatid segregation (GO:0033046) | 3.36898961 |
64 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.36898961 |
65 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.36898961 |
66 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.36898961 |
67 | telomere maintenance via telomere lengthening (GO:0010833) | 3.33585631 |
68 | protein complex localization (GO:0031503) | 3.33426290 |
69 | regulation of translational fidelity (GO:0006450) | 3.32135946 |
70 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.31578463 |
71 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.31578463 |
72 | DNA conformation change (GO:0071103) | 3.30802404 |
73 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.30559688 |
74 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.30559688 |
75 | negative regulation of mRNA metabolic process (GO:1903312) | 3.28094846 |
76 | pre-miRNA processing (GO:0031054) | 3.25368457 |
77 | regulation of sister chromatid segregation (GO:0033045) | 3.24622027 |
78 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.24622027 |
79 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.24622027 |
80 | mitotic spindle assembly checkpoint (GO:0007094) | 3.21203928 |
81 | DNA synthesis involved in DNA repair (GO:0000731) | 3.20405574 |
82 | chromosome condensation (GO:0030261) | 3.19380140 |
83 | chromosome segregation (GO:0007059) | 3.17821293 |
84 | spindle assembly checkpoint (GO:0071173) | 3.16088355 |
85 | regulation of centrosome cycle (GO:0046605) | 3.15957947 |
86 | protein localization to chromosome (GO:0034502) | 3.11555413 |
87 | chromatin assembly or disassembly (GO:0006333) | 3.11420242 |
88 | sister chromatid cohesion (GO:0007062) | 3.10577441 |
89 | L-serine metabolic process (GO:0006563) | 3.10505758 |
90 | negative regulation of RNA splicing (GO:0033119) | 3.05526431 |
91 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.04167913 |
92 | DNA strand renaturation (GO:0000733) | 3.02603986 |
93 | telomere maintenance (GO:0000723) | 3.01299785 |
94 | telomere organization (GO:0032200) | 2.99499564 |
95 | DNA double-strand break processing (GO:0000729) | 2.99129101 |
96 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.97990504 |
97 | regulation of centrosome duplication (GO:0010824) | 2.95676703 |
98 | base-excision repair (GO:0006284) | 2.95154965 |
99 | cellular protein complex localization (GO:0034629) | 2.95116293 |
100 | regulation of helicase activity (GO:0051095) | 2.95082487 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 5.09328644 |
2 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.64326962 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.08811276 |
4 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.71494850 |
5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.26411357 |
6 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 3.08746082 |
7 | AR_21909140_ChIP-Seq_LNCAP_Human | 3.06821376 |
8 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.93835682 |
9 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.86151759 |
10 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.75193860 |
11 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.71368220 |
12 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.70146789 |
13 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.55804188 |
14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.54209597 |
15 | * EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.42004959 |
16 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.41146861 |
17 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.39905841 |
18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.36771837 |
19 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.35387624 |
20 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 2.27397377 |
21 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.26779587 |
22 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.19254165 |
23 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.17332673 |
24 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.17308611 |
25 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.15963098 |
26 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.10466179 |
27 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.04138740 |
28 | E2F7_22180533_ChIP-Seq_HELA_Human | 10.8111758 |
29 | * POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.97622739 |
30 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.96237129 |
31 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.93144048 |
32 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.90742955 |
33 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.89782889 |
34 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.89256853 |
35 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.87552921 |
36 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.85581854 |
37 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.79190251 |
38 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.77281511 |
39 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.76357139 |
40 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.71262671 |
41 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.62774325 |
42 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.59155057 |
43 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.53095938 |
44 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.51050264 |
45 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.47168854 |
46 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.45757453 |
47 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.45436559 |
48 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.45131189 |
49 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.37784521 |
50 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.35942559 |
51 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.35404096 |
52 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.35383635 |
53 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.34271200 |
54 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.32884666 |
55 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.32125591 |
56 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.22037899 |
57 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.18669916 |
58 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.14811549 |
59 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.13934182 |
60 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.13437059 |
61 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.12427725 |
62 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.12255504 |
63 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.11540827 |
64 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.10753762 |
65 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.06419511 |
66 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.04868801 |
67 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.02339313 |
68 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.01652277 |
69 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.01552130 |
70 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.00665480 |
71 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.00293922 |
72 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.99282496 |
73 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.98689965 |
74 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.98221782 |
75 | MYC_22102868_ChIP-Seq_BL_Human | 0.97490861 |
76 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.96190156 |
77 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.95712734 |
78 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.95003889 |
79 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.94766652 |
80 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.93229301 |
81 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.92607383 |
82 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.91121149 |
83 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.90417262 |
84 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.90327318 |
85 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.88919175 |
86 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 0.86188340 |
87 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.85407583 |
88 | * TFEB_21752829_ChIP-Seq_HELA_Human | 0.84980325 |
89 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.84949464 |
90 | EWS_26573619_Chip-Seq_HEK293_Human | 0.81201113 |
91 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.80143588 |
92 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.79888205 |
93 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.79000137 |
94 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.78779546 |
95 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.76518593 |
96 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.76320366 |
97 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.72122243 |
98 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.70953991 |
99 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.67476803 |
100 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.65940574 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010094_abnormal_chromosome_stability | 5.30979382 |
2 | MP0008057_abnormal_DNA_replication | 4.65217765 |
3 | MP0003693_abnormal_embryo_hatching | 4.63153714 |
4 | MP0003111_abnormal_nucleus_morphology | 4.49762558 |
5 | MP0004957_abnormal_blastocyst_morpholog | 4.11523095 |
6 | MP0008058_abnormal_DNA_repair | 3.85039425 |
7 | MP0003077_abnormal_cell_cycle | 3.72515378 |
8 | MP0008932_abnormal_embryonic_tissue | 2.97816220 |
9 | MP0008007_abnormal_cellular_replicative | 2.60919018 |
10 | MP0001730_embryonic_growth_arrest | 2.37286625 |
11 | MP0010352_gastrointestinal_tract_polyps | 2.29927254 |
12 | MP0003941_abnormal_skin_development | 2.17090887 |
13 | MP0000350_abnormal_cell_proliferation | 2.12269315 |
14 | MP0008877_abnormal_DNA_methylation | 2.09870198 |
15 | MP0009672_abnormal_birth_weight | 2.00394812 |
16 | MP0009697_abnormal_copulation | 1.98742900 |
17 | MP0003890_abnormal_embryonic-extraembry | 1.93670685 |
18 | MP0001672_abnormal_embryogenesis/_devel | 1.89191672 |
19 | MP0005380_embryogenesis_phenotype | 1.89191672 |
20 | MP0001697_abnormal_embryo_size | 1.81365258 |
21 | MP0010307_abnormal_tumor_latency | 1.80895441 |
22 | MP0002084_abnormal_developmental_patter | 1.76622042 |
23 | MP0002085_abnormal_embryonic_tissue | 1.69808128 |
24 | MP0003718_maternal_effect | 1.68047869 |
25 | MP0003984_embryonic_growth_retardation | 1.67921714 |
26 | MP0002080_prenatal_lethality | 1.64692005 |
27 | MP0001293_anophthalmia | 1.64671426 |
28 | MP0002088_abnormal_embryonic_growth/wei | 1.62678233 |
29 | MP0003937_abnormal_limbs/digits/tail_de | 1.59853736 |
30 | MP0004197_abnormal_fetal_growth/weight/ | 1.53453444 |
31 | MP0002697_abnormal_eye_size | 1.46444188 |
32 | MP0003786_premature_aging | 1.43895295 |
33 | MP0002396_abnormal_hematopoietic_system | 1.41037211 |
34 | MP0003567_abnormal_fetal_cardiomyocyte | 1.37179758 |
35 | MP0009703_decreased_birth_body | 1.35787078 |
36 | MP0000537_abnormal_urethra_morphology | 1.32274318 |
37 | MP0006292_abnormal_olfactory_placode | 1.31673428 |
38 | MP0000313_abnormal_cell_death | 1.29495090 |
39 | MP0002086_abnormal_extraembryonic_tissu | 1.28772957 |
40 | MP0003123_paternal_imprinting | 1.18970343 |
41 | MP0001286_abnormal_eye_development | 1.17419108 |
42 | MP0005076_abnormal_cell_differentiation | 1.16834992 |
43 | MP0002009_preneoplasia | 1.16112096 |
44 | MP0003315_abnormal_perineum_morphology | 1.15742184 |
45 | MP0002877_abnormal_melanocyte_morpholog | 1.11630422 |
46 | MP0006035_abnormal_mitochondrial_morpho | 1.09713078 |
47 | MP0010030_abnormal_orbit_morphology | 1.09479813 |
48 | MP0003121_genomic_imprinting | 1.08467331 |
49 | MP0003119_abnormal_digestive_system | 1.05541137 |
50 | MP0004233_abnormal_muscle_weight | 1.04321826 |
51 | MP0002233_abnormal_nose_morphology | 1.03189381 |
52 | MP0000428_abnormal_craniofacial_morphol | 1.03118703 |
53 | MP0002210_abnormal_sex_determination | 1.02546277 |
54 | MP0002111_abnormal_tail_morphology | 1.02003167 |
55 | MP0003861_abnormal_nervous_system | 0.99981777 |
56 | MP0002092_abnormal_eye_morphology | 0.97580886 |
57 | MP0000358_abnormal_cell_content/ | 0.96629528 |
58 | MP0001346_abnormal_lacrimal_gland | 0.94470560 |
59 | MP0003705_abnormal_hypodermis_morpholog | 0.93729662 |
60 | MP0003943_abnormal_hepatobiliary_system | 0.91317098 |
61 | MP0001929_abnormal_gametogenesis | 0.89930829 |
62 | MP0002938_white_spotting | 0.89776108 |
63 | MP0001145_abnormal_male_reproductive | 0.88382696 |
64 | MP0003221_abnormal_cardiomyocyte_apopto | 0.85167731 |
65 | MP0003115_abnormal_respiratory_system | 0.83321148 |
66 | MP0004185_abnormal_adipocyte_glucose | 0.83137694 |
67 | MP0002019_abnormal_tumor_incidence | 0.82919089 |
68 | MP0005384_cellular_phenotype | 0.81188164 |
69 | MP0004808_abnormal_hematopoietic_stem | 0.80709115 |
70 | MP0001661_extended_life_span | 0.78993072 |
71 | MP0003755_abnormal_palate_morphology | 0.78502379 |
72 | MP0000566_synostosis | 0.78093791 |
73 | MP0000579_abnormal_nail_morphology | 0.77951010 |
74 | MP0005623_abnormal_meninges_morphology | 0.76681745 |
75 | MP0003935_abnormal_craniofacial_develop | 0.76634254 |
76 | MP0000653_abnormal_sex_gland | 0.76308894 |
77 | MP0000432_abnormal_head_morphology | 0.76023715 |
78 | MP0003385_abnormal_body_wall | 0.75371356 |
79 | MP0000490_abnormal_crypts_of | 0.75043062 |
80 | MP0001299_abnormal_eye_distance/ | 0.75042522 |
81 | MP0005501_abnormal_skin_physiology | 0.74259759 |
82 | MP0005621_abnormal_cell_physiology | 0.72312631 |
83 | MP0002751_abnormal_autonomic_nervous | 0.70711653 |
84 | MP0001529_abnormal_vocalization | 0.69356111 |
85 | MP0002081_perinatal_lethality | 0.68738570 |
86 | MP0001915_intracranial_hemorrhage | 0.68334439 |
87 | MP0000762_abnormal_tongue_morphology | 0.67403881 |
88 | MP0002254_reproductive_system_inflammat | 0.66892694 |
89 | MP0001177_atelectasis | 0.66868577 |
90 | MP0009053_abnormal_anal_canal | 0.65396906 |
91 | MP0000049_abnormal_middle_ear | 0.63864425 |
92 | MP0005391_vision/eye_phenotype | 0.63597676 |
93 | MP0000647_abnormal_sebaceous_gland | 0.62501206 |
94 | MP0006072_abnormal_retinal_apoptosis | 0.62355661 |
95 | MP0001849_ear_inflammation | 0.61907772 |
96 | MP0002102_abnormal_ear_morphology | 0.60769551 |
97 | MP0001119_abnormal_female_reproductive | 0.60602063 |
98 | MP0002160_abnormal_reproductive_system | 0.60292220 |
99 | MP0003122_maternal_imprinting | 0.60240036 |
100 | MP0004264_abnormal_extraembryonic_tissu | 0.60070169 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 5.43589773 |
2 | Chromsome breakage (HP:0040012) | 5.12810527 |
3 | Increased nuchal translucency (HP:0010880) | 3.79214109 |
4 | Meckel diverticulum (HP:0002245) | 3.73480680 |
5 | Volvulus (HP:0002580) | 3.63743842 |
6 | Abnormality of chromosome stability (HP:0003220) | 3.57494119 |
7 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.55111808 |
8 | Abnormality of the ileum (HP:0001549) | 3.53417330 |
9 | Birth length less than 3rd percentile (HP:0003561) | 3.45989225 |
10 | Embryonal renal neoplasm (HP:0011794) | 3.36314483 |
11 | Abnormality of the preputium (HP:0100587) | 3.35980298 |
12 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.19416537 |
13 | Ependymoma (HP:0002888) | 3.17195269 |
14 | Cortical dysplasia (HP:0002539) | 3.09838675 |
15 | Abnormality of the labia minora (HP:0012880) | 3.04942803 |
16 | Abnormal lung lobation (HP:0002101) | 2.91152530 |
17 | Duodenal stenosis (HP:0100867) | 2.84513148 |
18 | Small intestinal stenosis (HP:0012848) | 2.84513148 |
19 | Multiple enchondromatosis (HP:0005701) | 2.79706952 |
20 | Colon cancer (HP:0003003) | 2.78580942 |
21 | Medulloblastoma (HP:0002885) | 2.74838557 |
22 | Proximal placement of thumb (HP:0009623) | 2.58869629 |
23 | Abnormality of the carotid arteries (HP:0005344) | 2.57804907 |
24 | Rhabdomyosarcoma (HP:0002859) | 2.54108533 |
25 | Abnormality of the duodenum (HP:0002246) | 2.50378218 |
26 | Deviation of the thumb (HP:0009603) | 2.48623625 |
27 | Myelodysplasia (HP:0002863) | 2.48609938 |
28 | High anterior hairline (HP:0009890) | 2.46362011 |
29 | Ectopic kidney (HP:0000086) | 2.41914609 |
30 | Absent radius (HP:0003974) | 2.41762244 |
31 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.39339571 |
32 | Glioma (HP:0009733) | 2.38494256 |
33 | Spastic diplegia (HP:0001264) | 2.37256530 |
34 | Microvesicular hepatic steatosis (HP:0001414) | 2.33329330 |
35 | Abnormality of the astrocytes (HP:0100707) | 2.32483719 |
36 | Astrocytoma (HP:0009592) | 2.32483719 |
37 | Cafe-au-lait spot (HP:0000957) | 2.27815707 |
38 | Selective tooth agenesis (HP:0001592) | 2.26577852 |
39 | Sloping forehead (HP:0000340) | 2.24823846 |
40 | Aplasia involving forearm bones (HP:0009822) | 2.24143232 |
41 | Absent forearm bone (HP:0003953) | 2.24143232 |
42 | Overlapping toe (HP:0001845) | 2.23417826 |
43 | Facial cleft (HP:0002006) | 2.14920264 |
44 | Embryonal neoplasm (HP:0002898) | 2.13311933 |
45 | Choanal atresia (HP:0000453) | 2.09414071 |
46 | Progressive external ophthalmoplegia (HP:0000590) | 2.06573750 |
47 | Neoplasm of the colon (HP:0100273) | 2.04255954 |
48 | Horseshoe kidney (HP:0000085) | 2.03992407 |
49 | Atresia of the external auditory canal (HP:0000413) | 2.01851345 |
50 | Triphalangeal thumb (HP:0001199) | 2.00383526 |
51 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.91640861 |
52 | Gastrointestinal carcinoma (HP:0002672) | 1.91640861 |
53 | Microglossia (HP:0000171) | 1.88405802 |
54 | Squamous cell carcinoma (HP:0002860) | 1.87751755 |
55 | Abnormality of chromosome segregation (HP:0002916) | 1.86729943 |
56 | Abnormality of glycolysis (HP:0004366) | 1.84210976 |
57 | Shoulder girdle muscle weakness (HP:0003547) | 1.82984718 |
58 | Deep philtrum (HP:0002002) | 1.81729809 |
59 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.80875986 |
60 | Reticulocytopenia (HP:0001896) | 1.80303174 |
61 | Skull defect (HP:0001362) | 1.78538399 |
62 | Neuroblastoma (HP:0003006) | 1.78524870 |
63 | Primitive neuroectodermal tumor (HP:0030065) | 1.78524870 |
64 | Neuroblastic tumors (HP:0004376) | 1.78524870 |
65 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 1.78524870 |
66 | Postnatal microcephaly (HP:0005484) | 1.78102398 |
67 | Carpal bone hypoplasia (HP:0001498) | 1.78050657 |
68 | Patellar aplasia (HP:0006443) | 1.75559109 |
69 | Clubbing of toes (HP:0100760) | 1.74938756 |
70 | Hepatoblastoma (HP:0002884) | 1.74192315 |
71 | Arteriovenous malformation (HP:0100026) | 1.72070253 |
72 | Abnormal number of incisors (HP:0011064) | 1.71442951 |
73 | Abnormality of cochlea (HP:0000375) | 1.71193292 |
74 | Neoplasm of striated muscle (HP:0009728) | 1.68918328 |
75 | Missing ribs (HP:0000921) | 1.67503874 |
76 | Irregular epiphyses (HP:0010582) | 1.66619966 |
77 | Nervous tissue neoplasm (HP:0030060) | 1.65501753 |
78 | Neuroectodermal neoplasm (HP:0030061) | 1.65501753 |
79 | Neuroepithelial neoplasm (HP:0030063) | 1.65501753 |
80 | Neoplasm of the adrenal cortex (HP:0100641) | 1.63169948 |
81 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.62576091 |
82 | Obsessive-compulsive behavior (HP:0000722) | 1.61050964 |
83 | Urethral obstruction (HP:0000796) | 1.60698380 |
84 | Uterine neoplasm (HP:0010784) | 1.60675344 |
85 | Leiomyosarcoma (HP:0100243) | 1.58805226 |
86 | Uterine leiomyosarcoma (HP:0002891) | 1.58805226 |
87 | Overriding aorta (HP:0002623) | 1.57605793 |
88 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.57090750 |
89 | Bifid tongue (HP:0010297) | 1.57060524 |
90 | Capillary hemangiomas (HP:0005306) | 1.56492669 |
91 | Abnormality of methionine metabolism (HP:0010901) | 1.56449814 |
92 | Absent epiphyses (HP:0010577) | 1.55374040 |
93 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.55374040 |
94 | Insomnia (HP:0100785) | 1.54770334 |
95 | Poikiloderma (HP:0001029) | 1.54687692 |
96 | Duplication of thumb phalanx (HP:0009942) | 1.54371397 |
97 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.53528075 |
98 | High pitched voice (HP:0001620) | 1.53206381 |
99 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.52985375 |
100 | Premature ovarian failure (HP:0008209) | 1.52675311 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDC7 | 4.38466221 |
2 | BUB1 | 3.96280881 |
3 | SRPK1 | 3.71179698 |
4 | TSSK6 | 3.63725623 |
5 | TTK | 3.61152736 |
6 | NEK1 | 3.14839815 |
7 | EIF2AK1 | 2.90490759 |
8 | MKNK1 | 2.43075639 |
9 | PLK4 | 2.35435984 |
10 | WEE1 | 2.32021549 |
11 | PLK3 | 2.27691472 |
12 | MKNK2 | 2.24404037 |
13 | PBK | 2.23261476 |
14 | VRK2 | 2.14682168 |
15 | EIF2AK3 | 2.04106037 |
16 | PNCK | 2.03589291 |
17 | TAF1 | 2.00976385 |
18 | CDK12 | 1.98456020 |
19 | SMG1 | 1.74488204 |
20 | MAP3K10 | 1.73738803 |
21 | ATR | 1.68504262 |
22 | PLK1 | 1.67234762 |
23 | BRD4 | 1.61892041 |
24 | BRSK2 | 1.60435120 |
25 | CHEK2 | 1.53338025 |
26 | NEK2 | 1.42148784 |
27 | LATS1 | 1.41882875 |
28 | ZAK | 1.41039586 |
29 | TRIM28 | 1.39079907 |
30 | CDK7 | 1.32202514 |
31 | CHEK1 | 1.31558361 |
32 | SCYL2 | 1.28903809 |
33 | PASK | 1.27628571 |
34 | NUAK1 | 1.24893750 |
35 | ALK | 1.19040374 |
36 | * AURKB | 1.18541951 |
37 | EEF2K | 1.18035121 |
38 | BRSK1 | 1.15399255 |
39 | VRK1 | 1.14475327 |
40 | ATM | 1.13836194 |
41 | MST4 | 1.07772230 |
42 | EIF2AK2 | 1.02457432 |
43 | RPS6KB2 | 0.97621486 |
44 | CDK6 | 0.93828086 |
45 | CAMK1G | 0.93216573 |
46 | STK16 | 0.91799195 |
47 | CLK1 | 0.89271953 |
48 | RPS6KA4 | 0.89134007 |
49 | CDK4 | 0.87940379 |
50 | FGFR1 | 0.86848447 |
51 | BCR | 0.81756708 |
52 | CDK1 | 0.80914707 |
53 | STK3 | 0.79300460 |
54 | CDK2 | 0.77075093 |
55 | STK4 | 0.73120067 |
56 | CSNK1E | 0.71345855 |
57 | MAP3K8 | 0.71137100 |
58 | AURKA | 0.69941529 |
59 | LATS2 | 0.69049542 |
60 | PAK4 | 0.68430190 |
61 | ERBB4 | 0.67839621 |
62 | CDK8 | 0.64230655 |
63 | STK38L | 0.64106140 |
64 | MET | 0.63989386 |
65 | MELK | 0.62182899 |
66 | MST1R | 0.60563012 |
67 | TNIK | 0.59447486 |
68 | CDK3 | 0.59239372 |
69 | PRKDC | 0.58952910 |
70 | CDK9 | 0.55344463 |
71 | STK10 | 0.54783172 |
72 | CSNK1G1 | 0.53871633 |
73 | CSNK2A2 | 0.52547649 |
74 | NME1 | 0.52029675 |
75 | NME2 | 0.50411603 |
76 | DYRK3 | 0.47193912 |
77 | YES1 | 0.43694602 |
78 | MAP3K9 | 0.43269354 |
79 | CDK18 | 0.43033447 |
80 | WNK3 | 0.42348061 |
81 | CAMK1D | 0.41920757 |
82 | CSNK2A1 | 0.41371576 |
83 | PLK2 | 0.41032545 |
84 | CDK11A | 0.39802664 |
85 | PDGFRA | 0.39490118 |
86 | CDK15 | 0.39363355 |
87 | DAPK1 | 0.38200766 |
88 | MTOR | 0.37593193 |
89 | ICK | 0.36687549 |
90 | CCNB1 | 0.34540673 |
91 | MAPK14 | 0.33929939 |
92 | CDK14 | 0.32747374 |
93 | FGFR2 | 0.31750962 |
94 | CSNK1G3 | 0.30568628 |
95 | CSNK1A1L | 0.30308508 |
96 | PKN2 | 0.30155445 |
97 | MAP4K2 | 0.28998193 |
98 | GSK3B | 0.28950397 |
99 | BRAF | 0.27509440 |
100 | RPS6KB1 | 0.25737147 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 5.04189883 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 4.34367983 |
3 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.66169905 |
4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.22447064 |
5 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 3.20065723 |
6 | Base excision repair_Homo sapiens_hsa03410 | 3.08160173 |
7 | Cell cycle_Homo sapiens_hsa04110 | 3.02453725 |
8 | Spliceosome_Homo sapiens_hsa03040 | 2.98304123 |
9 | RNA transport_Homo sapiens_hsa03013 | 2.90522958 |
10 | Homologous recombination_Homo sapiens_hsa03440 | 2.72531850 |
11 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.62157109 |
12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.57744293 |
13 | Proteasome_Homo sapiens_hsa03050 | 2.53660404 |
14 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.42557060 |
15 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.11101682 |
16 | RNA polymerase_Homo sapiens_hsa03020 | 1.93994763 |
17 | RNA degradation_Homo sapiens_hsa03018 | 1.74020916 |
18 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.67645187 |
19 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.63502079 |
20 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.60497035 |
21 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.58192316 |
22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.53770188 |
23 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.53188998 |
24 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.37490665 |
25 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.28736997 |
26 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.28418810 |
27 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.21501874 |
28 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.17804716 |
29 | Carbon metabolism_Homo sapiens_hsa01200 | 1.15983533 |
30 | Protein export_Homo sapiens_hsa03060 | 1.15458840 |
31 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.13577721 |
32 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.11353585 |
33 | Lysine degradation_Homo sapiens_hsa00310 | 1.07834969 |
34 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.07771482 |
35 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.06802488 |
36 | Purine metabolism_Homo sapiens_hsa00230 | 1.06293556 |
37 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.05263296 |
38 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.05041472 |
39 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.97889552 |
40 | Thyroid cancer_Homo sapiens_hsa05216 | 0.93257707 |
41 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.86512930 |
42 | Ribosome_Homo sapiens_hsa03010 | 0.85525458 |
43 | Adherens junction_Homo sapiens_hsa04520 | 0.85521831 |
44 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.84401554 |
45 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.81376518 |
46 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.77653281 |
47 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.76800667 |
48 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.73618171 |
49 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.69257779 |
50 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.69217523 |
51 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.68536482 |
52 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.67846178 |
53 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.62964295 |
54 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.62442859 |
55 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.62069756 |
56 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.61159881 |
57 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.61075200 |
58 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.59601933 |
59 | Colorectal cancer_Homo sapiens_hsa05210 | 0.58592276 |
60 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.55688935 |
61 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.54143300 |
62 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.52766924 |
63 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.51866924 |
64 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.49997279 |
65 | Prostate cancer_Homo sapiens_hsa05215 | 0.49296834 |
66 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.43061292 |
67 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.42341471 |
68 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.41945421 |
69 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.39868505 |
70 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.39030494 |
71 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.37306265 |
72 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.33908470 |
73 | Bladder cancer_Homo sapiens_hsa05219 | 0.33078169 |
74 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.32904473 |
75 | Tight junction_Homo sapiens_hsa04530 | 0.31702191 |
76 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.31239858 |
77 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.31088496 |
78 | HTLV-I infection_Homo sapiens_hsa05166 | 0.29278781 |
79 | Alcoholism_Homo sapiens_hsa05034 | 0.25651230 |
80 | Metabolic pathways_Homo sapiens_hsa01100 | 0.25218790 |
81 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.23343232 |
82 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.22116259 |
83 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.21687918 |
84 | Endometrial cancer_Homo sapiens_hsa05213 | 0.21293168 |
85 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.19556525 |
86 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.18741340 |
87 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.17936340 |
88 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.17600217 |
89 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.16196831 |
90 | Melanoma_Homo sapiens_hsa05218 | 0.16086324 |
91 | Sulfur relay system_Homo sapiens_hsa04122 | 0.15324358 |
92 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.13904253 |
93 | Huntingtons disease_Homo sapiens_hsa05016 | 0.13198150 |
94 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.12808311 |
95 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.12620149 |
96 | Pathways in cancer_Homo sapiens_hsa05200 | 0.11957531 |
97 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.08696373 |
98 | Galactose metabolism_Homo sapiens_hsa00052 | 0.07618204 |
99 | Apoptosis_Homo sapiens_hsa04210 | 0.05529868 |
100 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.04954545 |