

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 4.81770213 |
| 2 | regulation of mitotic spindle checkpoint (GO:1903504) | 4.81770213 |
| 3 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.80826222 |
| 4 | microtubule depolymerization (GO:0007019) | 4.66348162 |
| 5 | proteasome assembly (GO:0043248) | 4.53706076 |
| 6 | chromatin remodeling at centromere (GO:0031055) | 4.11717764 |
| 7 | CENP-A containing nucleosome assembly (GO:0034080) | 4.09957958 |
| 8 | DNA damage response, detection of DNA damage (GO:0042769) | 4.07316121 |
| 9 | protein neddylation (GO:0045116) | 4.00214013 |
| 10 | cullin deneddylation (GO:0010388) | 3.87897148 |
| 11 | DNA double-strand break processing (GO:0000729) | 3.87733161 |
| 12 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.87411169 |
| 13 | isotype switching (GO:0045190) | 3.87411169 |
| 14 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.87411169 |
| 15 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.81245015 |
| 16 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.78713552 |
| 17 | protein localization to kinetochore (GO:0034501) | 3.78366282 |
| 18 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.77465266 |
| 19 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.74193188 |
| 20 | base-excision repair, AP site formation (GO:0006285) | 3.71169355 |
| 21 | histone exchange (GO:0043486) | 3.68566624 |
| 22 | rRNA modification (GO:0000154) | 3.65911756 |
| 23 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.63859951 |
| 24 | protein deneddylation (GO:0000338) | 3.61432679 |
| 25 | DNA ligation (GO:0006266) | 3.61317813 |
| 26 | DNA replication checkpoint (GO:0000076) | 3.57717900 |
| 27 | establishment of integrated proviral latency (GO:0075713) | 3.56321985 |
| 28 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.51655970 |
| 29 | termination of RNA polymerase III transcription (GO:0006386) | 3.51655970 |
| 30 | IMP biosynthetic process (GO:0006188) | 3.50796630 |
| 31 | regulation of helicase activity (GO:0051095) | 3.49831840 |
| 32 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.48319641 |
| 33 | chaperone-mediated protein transport (GO:0072321) | 3.46705930 |
| 34 | mitotic metaphase plate congression (GO:0007080) | 3.45532034 |
| 35 | ribosome assembly (GO:0042255) | 3.42667538 |
| 36 | rRNA methylation (GO:0031167) | 3.34342537 |
| 37 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.33397914 |
| 38 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.32815189 |
| 39 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.32815189 |
| 40 | mitotic sister chromatid segregation (GO:0000070) | 3.32798125 |
| 41 | negative regulation of ligase activity (GO:0051352) | 3.27665797 |
| 42 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.27665797 |
| 43 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.26900754 |
| 44 | respiratory chain complex IV assembly (GO:0008535) | 3.25965634 |
| 45 | DNA deamination (GO:0045006) | 3.22358817 |
| 46 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.20939039 |
| 47 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.20872347 |
| 48 | mismatch repair (GO:0006298) | 3.18923444 |
| 49 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 3.16999785 |
| 50 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.14376727 |
| 51 | DNA strand elongation (GO:0022616) | 3.13483046 |
| 52 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.13339689 |
| 53 | sister chromatid segregation (GO:0000819) | 3.11268019 |
| 54 | protein-cofactor linkage (GO:0018065) | 3.10910869 |
| 55 | neuron fate determination (GO:0048664) | 3.10616914 |
| 56 | metaphase plate congression (GO:0051310) | 3.09819941 |
| 57 | histone mRNA metabolic process (GO:0008334) | 3.08881148 |
| 58 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.05778907 |
| 59 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.05778907 |
| 60 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.05778907 |
| 61 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.05005205 |
| 62 | branched-chain amino acid catabolic process (GO:0009083) | 3.03140653 |
| 63 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.00235363 |
| 64 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.00235363 |
| 65 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.00090839 |
| 66 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.99987964 |
| 67 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.99987964 |
| 68 | 7-methylguanosine mRNA capping (GO:0006370) | 2.97700473 |
| 69 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.97060910 |
| 70 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.97060910 |
| 71 | pseudouridine synthesis (GO:0001522) | 2.96672422 |
| 72 | regulation of centriole replication (GO:0046599) | 2.96117053 |
| 73 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.96116993 |
| 74 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.94892693 |
| 75 | DNA replication-independent nucleosome organization (GO:0034724) | 2.94892693 |
| 76 | somatic diversification of immunoglobulins (GO:0016445) | 2.91156231 |
| 77 | IMP metabolic process (GO:0046040) | 2.90631448 |
| 78 | somatic diversification of immune receptors via germline recombination within a single locus (GO:000 | 2.89876716 |
| 79 | somatic cell DNA recombination (GO:0016444) | 2.89876716 |
| 80 | 7-methylguanosine RNA capping (GO:0009452) | 2.89843173 |
| 81 | RNA capping (GO:0036260) | 2.89843173 |
| 82 | protein complex biogenesis (GO:0070271) | 2.89182125 |
| 83 | protein localization to chromosome, centromeric region (GO:0071459) | 2.88164628 |
| 84 | intracellular protein transmembrane import (GO:0044743) | 2.84398711 |
| 85 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.83654514 |
| 86 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.83504200 |
| 87 | NADH dehydrogenase complex assembly (GO:0010257) | 2.83504200 |
| 88 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.83504200 |
| 89 | spindle checkpoint (GO:0031577) | 2.82973815 |
| 90 | establishment of viral latency (GO:0019043) | 2.81236696 |
| 91 | centriole replication (GO:0007099) | 2.81178713 |
| 92 | mitotic spindle checkpoint (GO:0071174) | 2.80623113 |
| 93 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.79707018 |
| 94 | replication fork processing (GO:0031297) | 2.77177379 |
| 95 | cytochrome complex assembly (GO:0017004) | 2.75916379 |
| 96 | spliceosomal snRNP assembly (GO:0000387) | 2.75866640 |
| 97 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.73993142 |
| 98 | somatic diversification of immune receptors (GO:0002200) | 2.73472183 |
| 99 | negative regulation of DNA recombination (GO:0045910) | 2.72923176 |
| 100 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:0000288) | 2.70688570 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.69120807 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.03728860 |
| 3 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.73465690 |
| 4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.47936659 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.41545575 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.07497869 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.96704817 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.81608102 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.77324291 |
| 10 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.72072108 |
| 11 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.71874530 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.65340308 |
| 13 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.55046391 |
| 14 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.51714409 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.46753155 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.41976945 |
| 17 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.40337169 |
| 18 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.39838609 |
| 19 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.28087645 |
| 20 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.26679308 |
| 21 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.15525664 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.08396648 |
| 23 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.05879700 |
| 24 | EWS_26573619_Chip-Seq_HEK293_Human | 2.05104569 |
| 25 | VDR_22108803_ChIP-Seq_LS180_Human | 2.04027176 |
| 26 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.00694104 |
| 27 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.92253789 |
| 28 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.85307379 |
| 29 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.82642481 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.80814958 |
| 31 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.79083089 |
| 32 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.77523975 |
| 33 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.74603101 |
| 34 | FUS_26573619_Chip-Seq_HEK293_Human | 1.73375501 |
| 35 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.72578736 |
| 36 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.72352589 |
| 37 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.72277738 |
| 38 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.68619445 |
| 39 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.68347108 |
| 40 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.67183030 |
| 41 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.62320365 |
| 42 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.55861359 |
| 43 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.53566442 |
| 44 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.48150048 |
| 45 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.47636616 |
| 46 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.47581208 |
| 47 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.47120151 |
| 48 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.43993634 |
| 49 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.42649570 |
| 50 | P300_19829295_ChIP-Seq_ESCs_Human | 1.41673057 |
| 51 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.41454264 |
| 52 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.41425041 |
| 53 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.38520125 |
| 54 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.38479126 |
| 55 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.38340616 |
| 56 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.31065988 |
| 57 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.30325502 |
| 58 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.30302693 |
| 59 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.27866668 |
| 60 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.27705537 |
| 61 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.27316201 |
| 62 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.26539121 |
| 63 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.25712213 |
| 64 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.20911628 |
| 65 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.19688058 |
| 66 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.18760772 |
| 67 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.17617528 |
| 68 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.16831273 |
| 69 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.16194582 |
| 70 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.10789097 |
| 71 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.08332298 |
| 72 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.07864996 |
| 73 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.07417750 |
| 74 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.07397138 |
| 75 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.07101342 |
| 76 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.06523949 |
| 77 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.06512318 |
| 78 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.05626576 |
| 79 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.02643797 |
| 80 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.01696400 |
| 81 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.00927153 |
| 82 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.00748048 |
| 83 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.00259461 |
| 84 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.99819361 |
| 85 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.98376390 |
| 86 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.97536633 |
| 87 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.97020725 |
| 88 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.97020725 |
| 89 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.93961083 |
| 90 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.93438457 |
| 91 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.92853742 |
| 92 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.90601414 |
| 93 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.89505024 |
| 94 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.87840392 |
| 95 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.87840392 |
| 96 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.86512891 |
| 97 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.85330072 |
| 98 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.84357539 |
| 99 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.84357539 |
| 100 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.83715111 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 3.76948129 |
| 2 | MP0002102_abnormal_ear_morphology | 3.56777040 |
| 3 | MP0008058_abnormal_DNA_repair | 3.54672587 |
| 4 | MP0003693_abnormal_embryo_hatching | 3.33556269 |
| 5 | MP0008877_abnormal_DNA_methylation | 3.30036937 |
| 6 | MP0009697_abnormal_copulation | 3.11925598 |
| 7 | MP0004957_abnormal_blastocyst_morpholog | 2.99996735 |
| 8 | MP0003011_delayed_dark_adaptation | 2.78864660 |
| 9 | MP0004147_increased_porphyrin_level | 2.77246621 |
| 10 | MP0006072_abnormal_retinal_apoptosis | 2.65783532 |
| 11 | MP0000372_irregular_coat_pigmentation | 2.59842785 |
| 12 | MP0003718_maternal_effect | 2.58936117 |
| 13 | MP0003111_abnormal_nucleus_morphology | 2.40621554 |
| 14 | MP0003077_abnormal_cell_cycle | 2.31245346 |
| 15 | MP0001529_abnormal_vocalization | 2.15328330 |
| 16 | MP0005253_abnormal_eye_physiology | 2.09293533 |
| 17 | MP0008932_abnormal_embryonic_tissue | 2.04856653 |
| 18 | MP0003786_premature_aging | 1.96479757 |
| 19 | MP0002751_abnormal_autonomic_nervous | 1.95984687 |
| 20 | MP0008007_abnormal_cellular_replicative | 1.90462533 |
| 21 | MP0005084_abnormal_gallbladder_morpholo | 1.87194820 |
| 22 | MP0003119_abnormal_digestive_system | 1.86051976 |
| 23 | MP0003890_abnormal_embryonic-extraembry | 1.83002052 |
| 24 | MP0002736_abnormal_nociception_after | 1.73654611 |
| 25 | MP0005645_abnormal_hypothalamus_physiol | 1.71010050 |
| 26 | MP0008057_abnormal_DNA_replication | 1.56533272 |
| 27 | MP0001293_anophthalmia | 1.56183570 |
| 28 | MP0006292_abnormal_olfactory_placode | 1.47669298 |
| 29 | MP0003880_abnormal_central_pattern | 1.45773712 |
| 30 | MP0008872_abnormal_physiological_respon | 1.44103574 |
| 31 | MP0006035_abnormal_mitochondrial_morpho | 1.43061361 |
| 32 | MP0005377_hearing/vestibular/ear_phenot | 1.42976964 |
| 33 | MP0003878_abnormal_ear_physiology | 1.42976964 |
| 34 | MP0002234_abnormal_pharynx_morphology | 1.41331647 |
| 35 | MP0005551_abnormal_eye_electrophysiolog | 1.40293350 |
| 36 | MP0003937_abnormal_limbs/digits/tail_de | 1.40137670 |
| 37 | MP0002837_dystrophic_cardiac_calcinosis | 1.35189704 |
| 38 | MP0008789_abnormal_olfactory_epithelium | 1.35027114 |
| 39 | MP0003941_abnormal_skin_development | 1.33234116 |
| 40 | MP0004742_abnormal_vestibular_system | 1.27548761 |
| 41 | MP0002928_abnormal_bile_duct | 1.26087729 |
| 42 | MP0002138_abnormal_hepatobiliary_system | 1.16620409 |
| 43 | MP0006036_abnormal_mitochondrial_physio | 1.16431461 |
| 44 | MP0005075_abnormal_melanosome_morpholog | 1.15597121 |
| 45 | MP0001968_abnormal_touch/_nociception | 1.13191393 |
| 46 | MP0001929_abnormal_gametogenesis | 1.12586570 |
| 47 | MP0004133_heterotaxia | 1.12212995 |
| 48 | MP0004142_abnormal_muscle_tone | 1.12174068 |
| 49 | MP0002938_white_spotting | 1.08362206 |
| 50 | MP0005391_vision/eye_phenotype | 1.07764145 |
| 51 | MP0006276_abnormal_autonomic_nervous | 1.06761517 |
| 52 | MP0001286_abnormal_eye_development | 1.06506939 |
| 53 | MP0003121_genomic_imprinting | 1.06070032 |
| 54 | MP0004215_abnormal_myocardial_fiber | 1.05774373 |
| 55 | MP0005410_abnormal_fertilization | 1.04766342 |
| 56 | MP0002210_abnormal_sex_determination | 1.03841661 |
| 57 | MP0003122_maternal_imprinting | 1.03647294 |
| 58 | MP0000049_abnormal_middle_ear | 1.03624404 |
| 59 | MP0004197_abnormal_fetal_growth/weight/ | 1.02925975 |
| 60 | MP0001764_abnormal_homeostasis | 1.00029123 |
| 61 | MP0001177_atelectasis | 0.98466146 |
| 62 | MP0000350_abnormal_cell_proliferation | 0.97521501 |
| 63 | MP0005671_abnormal_response_to | 0.97395277 |
| 64 | MP0008995_early_reproductive_senescence | 0.97213177 |
| 65 | MP0003950_abnormal_plasma_membrane | 0.96367471 |
| 66 | MP0002084_abnormal_developmental_patter | 0.95404818 |
| 67 | MP0009046_muscle_twitch | 0.93058531 |
| 68 | MP0001984_abnormal_olfaction | 0.92665327 |
| 69 | MP0001145_abnormal_male_reproductive | 0.85841695 |
| 70 | MP0002090_abnormal_vision | 0.83142099 |
| 71 | MP0000653_abnormal_sex_gland | 0.82736541 |
| 72 | MP0000631_abnormal_neuroendocrine_gland | 0.82638019 |
| 73 | MP0003195_calcinosis | 0.82335905 |
| 74 | MP0001697_abnormal_embryo_size | 0.81823527 |
| 75 | MP0001485_abnormal_pinna_reflex | 0.81254883 |
| 76 | MP0002085_abnormal_embryonic_tissue | 0.80986988 |
| 77 | MP0001119_abnormal_female_reproductive | 0.78782082 |
| 78 | MP0002697_abnormal_eye_size | 0.78686826 |
| 79 | MP0000613_abnormal_salivary_gland | 0.78166354 |
| 80 | MP0000358_abnormal_cell_content/ | 0.76027862 |
| 81 | MP0001672_abnormal_embryogenesis/_devel | 0.75908493 |
| 82 | MP0005380_embryogenesis_phenotype | 0.75908493 |
| 83 | MP0008775_abnormal_heart_ventricle | 0.71833571 |
| 84 | MP0002638_abnormal_pupillary_reflex | 0.71579113 |
| 85 | MP0003698_abnormal_male_reproductive | 0.69967640 |
| 86 | MP0001188_hyperpigmentation | 0.68086613 |
| 87 | MP0003943_abnormal_hepatobiliary_system | 0.67810367 |
| 88 | MP0002111_abnormal_tail_morphology | 0.67136803 |
| 89 | MP0001730_embryonic_growth_arrest | 0.65370150 |
| 90 | MP0004782_abnormal_surfactant_physiolog | 0.65078511 |
| 91 | MP0005395_other_phenotype | 0.64987341 |
| 92 | MP0002233_abnormal_nose_morphology | 0.64901453 |
| 93 | MP0003283_abnormal_digestive_organ | 0.63921866 |
| 94 | MP0009703_decreased_birth_body | 0.63825879 |
| 95 | MP0008875_abnormal_xenobiotic_pharmacok | 0.63221428 |
| 96 | MP0003567_abnormal_fetal_cardiomyocyte | 0.61155643 |
| 97 | MP0002254_reproductive_system_inflammat | 0.60947088 |
| 98 | MP0005167_abnormal_blood-brain_barrier | 0.60339459 |
| 99 | MP0002080_prenatal_lethality | 0.60115442 |
| 100 | MP0005195_abnormal_posterior_eye | 0.59735056 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the labia minora (HP:0012880) | 3.90830612 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 3.54786963 |
| 3 | Hypoplasia of the pons (HP:0012110) | 3.47150386 |
| 4 | Abnormality of the pons (HP:0007361) | 3.39727640 |
| 5 | Colon cancer (HP:0003003) | 3.31070798 |
| 6 | Acute encephalopathy (HP:0006846) | 3.16862007 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.08479190 |
| 8 | Pancreatic cysts (HP:0001737) | 3.00904783 |
| 9 | Progressive macrocephaly (HP:0004481) | 2.97418797 |
| 10 | Mitochondrial inheritance (HP:0001427) | 2.94091103 |
| 11 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.86759539 |
| 12 | Meckel diverticulum (HP:0002245) | 2.84971545 |
| 13 | Increased CSF lactate (HP:0002490) | 2.83059900 |
| 14 | Abnormality of the ileum (HP:0001549) | 2.77334011 |
| 15 | Hypothermia (HP:0002045) | 2.77230157 |
| 16 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.76078350 |
| 17 | Pendular nystagmus (HP:0012043) | 2.67448383 |
| 18 | Abnormality of midbrain morphology (HP:0002418) | 2.65476354 |
| 19 | Molar tooth sign on MRI (HP:0002419) | 2.65476354 |
| 20 | Abnormality of the preputium (HP:0100587) | 2.59828857 |
| 21 | Chromsome breakage (HP:0040012) | 2.57776572 |
| 22 | Renal cortical cysts (HP:0000803) | 2.54955378 |
| 23 | Abnormality of chromosome stability (HP:0003220) | 2.52656338 |
| 24 | Pancreatic fibrosis (HP:0100732) | 2.52154143 |
| 25 | Thyroid-stimulating hormone excess (HP:0002925) | 2.51756064 |
| 26 | Hepatocellular necrosis (HP:0001404) | 2.50764879 |
| 27 | Ependymoma (HP:0002888) | 2.50645492 |
| 28 | Increased hepatocellular lipid droplets (HP:0006565) | 2.46249425 |
| 29 | Cerebral edema (HP:0002181) | 2.40725176 |
| 30 | Methylmalonic acidemia (HP:0002912) | 2.40432904 |
| 31 | Lipid accumulation in hepatocytes (HP:0006561) | 2.39444644 |
| 32 | True hermaphroditism (HP:0010459) | 2.39046119 |
| 33 | Small intestinal stenosis (HP:0012848) | 2.32931046 |
| 34 | Duodenal stenosis (HP:0100867) | 2.32931046 |
| 35 | Congenital, generalized hypertrichosis (HP:0004540) | 2.32677841 |
| 36 | Hepatic necrosis (HP:0002605) | 2.32672268 |
| 37 | Short tibia (HP:0005736) | 2.32276865 |
| 38 | Medial flaring of the eyebrow (HP:0010747) | 2.27191912 |
| 39 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.26705017 |
| 40 | Chronic hepatic failure (HP:0100626) | 2.25691082 |
| 41 | Abnormality of the renal cortex (HP:0011035) | 2.25110725 |
| 42 | Abolished electroretinogram (ERG) (HP:0000550) | 2.22969123 |
| 43 | Type I transferrin isoform profile (HP:0003642) | 2.22812853 |
| 44 | Nephronophthisis (HP:0000090) | 2.21111146 |
| 45 | IgG deficiency (HP:0004315) | 2.14985312 |
| 46 | Volvulus (HP:0002580) | 2.13947274 |
| 47 | Increased serum lactate (HP:0002151) | 2.12582642 |
| 48 | Abnormality of methionine metabolism (HP:0010901) | 2.12053139 |
| 49 | Carpal bone hypoplasia (HP:0001498) | 2.11478852 |
| 50 | Abnormality of the duodenum (HP:0002246) | 2.10889349 |
| 51 | Neonatal respiratory distress (HP:0002643) | 2.07450628 |
| 52 | Posterior subcapsular cataract (HP:0007787) | 2.04993341 |
| 53 | Abnormal lung lobation (HP:0002101) | 2.04157934 |
| 54 | Optic disc pallor (HP:0000543) | 2.02722330 |
| 55 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.02230263 |
| 56 | Sloping forehead (HP:0000340) | 2.02169861 |
| 57 | Birth length less than 3rd percentile (HP:0003561) | 2.00501183 |
| 58 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.97702955 |
| 59 | Abnormality of the carotid arteries (HP:0005344) | 1.97480829 |
| 60 | Abnormal biliary tract physiology (HP:0012439) | 1.97304207 |
| 61 | Bile duct proliferation (HP:0001408) | 1.97304207 |
| 62 | Leukodystrophy (HP:0002415) | 1.96345262 |
| 63 | Duplicated collecting system (HP:0000081) | 1.95553589 |
| 64 | Progressive inability to walk (HP:0002505) | 1.94471262 |
| 65 | Attenuation of retinal blood vessels (HP:0007843) | 1.93219535 |
| 66 | Postnatal microcephaly (HP:0005484) | 1.92778013 |
| 67 | Abnormality of the renal collecting system (HP:0004742) | 1.92204561 |
| 68 | Lactic acidosis (HP:0003128) | 1.92014766 |
| 69 | Clubbing of toes (HP:0100760) | 1.91672773 |
| 70 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.91326658 |
| 71 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.91326658 |
| 72 | Abnormal protein glycosylation (HP:0012346) | 1.91326658 |
| 73 | Abnormal glycosylation (HP:0012345) | 1.91326658 |
| 74 | Absent thumb (HP:0009777) | 1.90927726 |
| 75 | Triphalangeal thumb (HP:0001199) | 1.87919920 |
| 76 | Horseshoe kidney (HP:0000085) | 1.87390444 |
| 77 | Constricted visual fields (HP:0001133) | 1.87262587 |
| 78 | Sclerocornea (HP:0000647) | 1.85337316 |
| 79 | Septo-optic dysplasia (HP:0100842) | 1.85118565 |
| 80 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.84681505 |
| 81 | Methylmalonic aciduria (HP:0012120) | 1.84180903 |
| 82 | Glioma (HP:0009733) | 1.83996260 |
| 83 | Nephrogenic diabetes insipidus (HP:0009806) | 1.83674518 |
| 84 | Chorioretinal atrophy (HP:0000533) | 1.79363318 |
| 85 | Fibular aplasia (HP:0002990) | 1.79293728 |
| 86 | Anencephaly (HP:0002323) | 1.78492642 |
| 87 | Congenital primary aphakia (HP:0007707) | 1.76914380 |
| 88 | Lissencephaly (HP:0001339) | 1.74486756 |
| 89 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.73302894 |
| 90 | Embryonal renal neoplasm (HP:0011794) | 1.71117637 |
| 91 | Intestinal atresia (HP:0011100) | 1.70549020 |
| 92 | Lethargy (HP:0001254) | 1.69102545 |
| 93 | Absent radius (HP:0003974) | 1.67480119 |
| 94 | Prostate neoplasm (HP:0100787) | 1.67205571 |
| 95 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.67203121 |
| 96 | Prominent metopic ridge (HP:0005487) | 1.67130335 |
| 97 | Respiratory failure (HP:0002878) | 1.67034271 |
| 98 | Postaxial foot polydactyly (HP:0001830) | 1.67028829 |
| 99 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.66949406 |
| 100 | Abnormality of serum amino acid levels (HP:0003112) | 1.66747910 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 4.74788821 |
| 2 | BUB1 | 3.95327030 |
| 3 | TSSK6 | 3.15260541 |
| 4 | EIF2AK3 | 3.12872476 |
| 5 | SRPK1 | 2.84189186 |
| 6 | TRIM28 | 2.57461560 |
| 7 | PLK3 | 2.45015112 |
| 8 | NUAK1 | 2.44528513 |
| 9 | CDC7 | 2.41927909 |
| 10 | MKNK1 | 2.28056506 |
| 11 | ZAK | 2.25489070 |
| 12 | VRK2 | 2.17788564 |
| 13 | VRK1 | 2.12620346 |
| 14 | MST4 | 2.06289322 |
| 15 | NEK1 | 2.05783548 |
| 16 | BRSK2 | 2.04186751 |
| 17 | MKNK2 | 2.03094780 |
| 18 | WNK3 | 2.02510569 |
| 19 | TXK | 1.99183388 |
| 20 | TTK | 1.89535614 |
| 21 | TNIK | 1.78202981 |
| 22 | TAF1 | 1.77671780 |
| 23 | EIF2AK1 | 1.73470526 |
| 24 | BCR | 1.66372340 |
| 25 | PBK | 1.55867794 |
| 26 | PLK4 | 1.49658740 |
| 27 | STK16 | 1.48826327 |
| 28 | FRK | 1.47489277 |
| 29 | ERBB3 | 1.38664013 |
| 30 | MAP3K4 | 1.34100817 |
| 31 | WEE1 | 1.27763087 |
| 32 | GRK1 | 1.18201560 |
| 33 | GRK7 | 1.17610474 |
| 34 | EIF2AK2 | 1.17256046 |
| 35 | CSNK1G1 | 1.16562852 |
| 36 | PNCK | 1.13779728 |
| 37 | TLK1 | 1.13347568 |
| 38 | BCKDK | 1.11035694 |
| 39 | CSNK1G3 | 1.05543535 |
| 40 | RPS6KA4 | 1.05062544 |
| 41 | NME1 | 1.03195772 |
| 42 | PLK1 | 1.02586776 |
| 43 | PLK2 | 1.01868661 |
| 44 | STK10 | 0.99352162 |
| 45 | BRSK1 | 0.97890829 |
| 46 | CSNK1G2 | 0.97451022 |
| 47 | PASK | 0.93220466 |
| 48 | CSNK1A1L | 0.93115821 |
| 49 | OXSR1 | 0.92864235 |
| 50 | BMPR1B | 0.91934276 |
| 51 | AURKB | 0.91600263 |
| 52 | ADRBK2 | 0.85037074 |
| 53 | MAP2K7 | 0.84808173 |
| 54 | DYRK3 | 0.83460091 |
| 55 | STK38L | 0.78058057 |
| 56 | NEK2 | 0.75511306 |
| 57 | ATR | 0.71524193 |
| 58 | DAPK1 | 0.70294861 |
| 59 | GRK5 | 0.69836034 |
| 60 | CHEK2 | 0.69579153 |
| 61 | MAPK15 | 0.64718656 |
| 62 | ACVR1B | 0.64705499 |
| 63 | ALK | 0.63671858 |
| 64 | CDK19 | 0.60170669 |
| 65 | KIT | 0.56653162 |
| 66 | TGFBR1 | 0.54833141 |
| 67 | PRKCE | 0.52834939 |
| 68 | ATM | 0.50995833 |
| 69 | CCNB1 | 0.49599916 |
| 70 | MST1R | 0.49189416 |
| 71 | SIK3 | 0.49079875 |
| 72 | TIE1 | 0.48327012 |
| 73 | CHEK1 | 0.45801446 |
| 74 | TGFBR2 | 0.44065525 |
| 75 | MOS | 0.42294435 |
| 76 | CSNK2A1 | 0.41898900 |
| 77 | FGFR1 | 0.40875869 |
| 78 | PAK4 | 0.38819294 |
| 79 | CDK3 | 0.38628363 |
| 80 | DYRK2 | 0.38162478 |
| 81 | INSRR | 0.37429427 |
| 82 | AURKA | 0.35291072 |
| 83 | RPS6KA5 | 0.33399948 |
| 84 | LATS1 | 0.33169773 |
| 85 | CSNK1E | 0.33077743 |
| 86 | PRKCG | 0.32142059 |
| 87 | IGF1R | 0.31929969 |
| 88 | ADRBK1 | 0.31331514 |
| 89 | MAPK13 | 0.30386950 |
| 90 | TEC | 0.29946239 |
| 91 | ERBB4 | 0.29407342 |
| 92 | CDK6 | 0.29171440 |
| 93 | DAPK2 | 0.28405167 |
| 94 | STK3 | 0.28386080 |
| 95 | CSNK2A2 | 0.28341941 |
| 96 | CSNK1A1 | 0.27513930 |
| 97 | BRD4 | 0.26829202 |
| 98 | MINK1 | 0.24864118 |
| 99 | NLK | 0.24054749 |
| 100 | ITK | 0.22470471 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.28870847 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.27034008 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 3.21886320 |
| 4 | Mismatch repair_Homo sapiens_hsa03430 | 3.17662815 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.11051625 |
| 6 | DNA replication_Homo sapiens_hsa03030 | 2.92303604 |
| 7 | Homologous recombination_Homo sapiens_hsa03440 | 2.45627468 |
| 8 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.27152459 |
| 9 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.26440044 |
| 10 | RNA degradation_Homo sapiens_hsa03018 | 2.24406700 |
| 11 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.21320916 |
| 12 | Spliceosome_Homo sapiens_hsa03040 | 2.19204992 |
| 13 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.15131617 |
| 14 | Basal transcription factors_Homo sapiens_hsa03022 | 2.15042515 |
| 15 | RNA transport_Homo sapiens_hsa03013 | 1.97133019 |
| 16 | Base excision repair_Homo sapiens_hsa03410 | 1.94450430 |
| 17 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.91317791 |
| 18 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.91043201 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.89370779 |
| 20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.76163380 |
| 21 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.71487967 |
| 22 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.68213957 |
| 23 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.65198875 |
| 24 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.63162063 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.57804784 |
| 26 | Parkinsons disease_Homo sapiens_hsa05012 | 1.55974660 |
| 27 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.53691349 |
| 28 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.50530236 |
| 29 | Cell cycle_Homo sapiens_hsa04110 | 1.44288844 |
| 30 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.39655693 |
| 31 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.35257938 |
| 32 | Purine metabolism_Homo sapiens_hsa00230 | 1.34668092 |
| 33 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.26066437 |
| 34 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.23856072 |
| 35 | Huntingtons disease_Homo sapiens_hsa05016 | 1.20320704 |
| 36 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.16583274 |
| 37 | Ribosome_Homo sapiens_hsa03010 | 1.10667961 |
| 38 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.10618577 |
| 39 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.10143954 |
| 40 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.00293189 |
| 41 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.99121047 |
| 42 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.98452735 |
| 43 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.92678925 |
| 44 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.91496773 |
| 45 | Peroxisome_Homo sapiens_hsa04146 | 0.90446355 |
| 46 | Alzheimers disease_Homo sapiens_hsa05010 | 0.86930114 |
| 47 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.84556248 |
| 48 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.82923551 |
| 49 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.82435480 |
| 50 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.77464984 |
| 51 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.77200506 |
| 52 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.76983106 |
| 53 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.72537472 |
| 54 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.72275322 |
| 55 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.71402399 |
| 56 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.67499189 |
| 57 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.64613765 |
| 58 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.64143387 |
| 59 | Metabolic pathways_Homo sapiens_hsa01100 | 0.62060383 |
| 60 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.61780208 |
| 61 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.59489825 |
| 62 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.56314769 |
| 63 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.54119004 |
| 64 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.53482654 |
| 65 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.53091048 |
| 66 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.52387959 |
| 67 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.51329673 |
| 68 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.51268029 |
| 69 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.51061064 |
| 70 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.50911881 |
| 71 | Retinol metabolism_Homo sapiens_hsa00830 | 0.50703304 |
| 72 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.50618503 |
| 73 | Nicotine addiction_Homo sapiens_hsa05033 | 0.50380030 |
| 74 | Olfactory transduction_Homo sapiens_hsa04740 | 0.49569742 |
| 75 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.48903757 |
| 76 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.47146877 |
| 77 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.46285527 |
| 78 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.45868834 |
| 79 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.45642958 |
| 80 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.45624120 |
| 81 | Asthma_Homo sapiens_hsa05310 | 0.42500727 |
| 82 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.42327199 |
| 83 | Carbon metabolism_Homo sapiens_hsa01200 | 0.40470037 |
| 84 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.39781487 |
| 85 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.38844787 |
| 86 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.37669479 |
| 87 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.37653043 |
| 88 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.36054735 |
| 89 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.34932029 |
| 90 | Taste transduction_Homo sapiens_hsa04742 | 0.34090096 |
| 91 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.31676026 |
| 92 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.31399863 |
| 93 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.30837082 |
| 94 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.30222680 |
| 95 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.29948095 |
| 96 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.26778353 |
| 97 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.26417240 |
| 98 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.24994318 |
| 99 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.24367987 |
| 100 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.23300062 |

