SUPV3L1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)5.18068884
2protein localization to kinetochore (GO:0034501)5.03768171
3DNA replication initiation (GO:0006270)4.74546029
4DNA replication checkpoint (GO:0000076)4.64332582
5metaphase plate congression (GO:0051310)4.58973352
6DNA strand elongation involved in DNA replication (GO:0006271)4.47244050
7folic acid-containing compound biosynthetic process (GO:0009396)4.32245831
8protein localization to chromosome, centromeric region (GO:0071459)4.28679802
9DNA strand elongation (GO:0022616)4.25659758
10telomere maintenance via semi-conservative replication (GO:0032201)4.11250816
11nucleobase biosynthetic process (GO:0046112)4.10958474
12DNA unwinding involved in DNA replication (GO:0006268)3.98730422
13mitotic nuclear envelope disassembly (GO:0007077)3.96279506
14CENP-A containing nucleosome assembly (GO:0034080)3.95443622
15folic acid metabolic process (GO:0046655)3.95390229
16chromatin remodeling at centromere (GO:0031055)3.93598507
17purine nucleobase biosynthetic process (GO:0009113)3.89917944
18maturation of SSU-rRNA (GO:0030490)3.83449009
19establishment of chromosome localization (GO:0051303)3.81353321
20ribosome assembly (GO:0042255)3.77679942
21formation of translation preinitiation complex (GO:0001731)3.73151478
22kinetochore assembly (GO:0051382)3.72745013
23ribosomal small subunit assembly (GO:0000028)3.71608104
24kinetochore organization (GO:0051383)3.71553185
25nuclear pore organization (GO:0006999)3.70034215
26ribosome biogenesis (GO:0042254)3.68473481
27telomere maintenance via recombination (GO:0000722)3.66673627
28regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.61835043
29membrane disassembly (GO:0030397)3.61163483
30nuclear envelope disassembly (GO:0051081)3.61163483
31ribosomal large subunit biogenesis (GO:0042273)3.58290321
32IMP biosynthetic process (GO:0006188)3.54990078
33DNA replication-independent nucleosome assembly (GO:0006336)3.52096830
34DNA replication-independent nucleosome organization (GO:0034724)3.52096830
35DNA deamination (GO:0045006)3.51739349
36attachment of spindle microtubules to kinetochore (GO:0008608)3.48922750
37mitotic recombination (GO:0006312)3.45974938
38replication fork processing (GO:0031297)3.45046350
39mitotic sister chromatid segregation (GO:0000070)3.44911995
40telomere maintenance via telomere lengthening (GO:0010833)3.42665240
41ribonucleoprotein complex biogenesis (GO:0022613)3.40687329
42DNA replication-dependent nucleosome organization (GO:0034723)3.33641979
43DNA replication-dependent nucleosome assembly (GO:0006335)3.33641979
44intra-S DNA damage checkpoint (GO:0031573)3.31161955
45negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.30333469
46regulation of mitotic spindle checkpoint (GO:1903504)3.27241945
47regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.27241945
48histone exchange (GO:0043486)3.26716007
49regulation of spindle organization (GO:0090224)3.26642655
50nuclear pore complex assembly (GO:0051292)3.23728783
51mitotic chromosome condensation (GO:0007076)3.23626637
52meiotic chromosome segregation (GO:0045132)3.23554785
53* mitochondrial RNA metabolic process (GO:0000959)3.23049213
54maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.21134780
55regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.20560275
56tRNA aminoacylation (GO:0043039)3.20221627
57amino acid activation (GO:0043038)3.20221627
58tRNA aminoacylation for protein translation (GO:0006418)3.20074563
59proteasome assembly (GO:0043248)3.19805605
60IMP metabolic process (GO:0046040)3.18052966
61negative regulation of translational initiation (GO:0045947)3.17069033
62viral mRNA export from host cell nucleus (GO:0046784)3.16697251
63L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.16653629
64pseudouridine synthesis (GO:0001522)3.16498271
65RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.15587361
66protein localization to chromosome (GO:0034502)3.14913652
67glycine metabolic process (GO:0006544)3.14780359
68regulation of nuclear cell cycle DNA replication (GO:0033262)3.13823419
69cullin deneddylation (GO:0010388)3.13106606
70rRNA processing (GO:0006364)3.12227476
71positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.10301554
72nucleotide-excision repair, DNA gap filling (GO:0006297)3.09122313
73translational termination (GO:0006415)3.08824170
74DNA catabolic process, exonucleolytic (GO:0000738)3.07302528
75viral transcription (GO:0019083)3.06331270
76rRNA metabolic process (GO:0016072)3.05192514
77regulation of centriole replication (GO:0046599)3.04442730
78translational initiation (GO:0006413)3.02123908
79negative regulation of chromosome segregation (GO:0051985)3.02056605
80spindle checkpoint (GO:0031577)3.01827406
81synapsis (GO:0007129)2.99472699
82chromatin assembly or disassembly (GO:0006333)2.99301972
83negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.98938866
84negative regulation of ligase activity (GO:0051352)2.98552043
85negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.98552043
86negative regulation of mitotic sister chromatid separation (GO:2000816)2.98104299
87negative regulation of mitotic sister chromatid segregation (GO:0033048)2.98104299
88negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.98104299
89negative regulation of sister chromatid segregation (GO:0033046)2.98104299
90maturation of 5.8S rRNA (GO:0000460)2.97927786
91proline biosynthetic process (GO:0006561)2.97655826
92* DNA duplex unwinding (GO:0032508)2.97348992
93sister chromatid segregation (GO:0000819)2.97125827
94non-recombinational repair (GO:0000726)2.97050716
95double-strand break repair via nonhomologous end joining (GO:0006303)2.97050716
96* DNA geometric change (GO:0032392)2.96774398
97somatic diversification of immune receptors via somatic mutation (GO:0002566)2.96284495
98somatic hypermutation of immunoglobulin genes (GO:0016446)2.96284495
99exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.96063471
100peptidyl-histidine modification (GO:0018202)2.95736836
101spindle assembly checkpoint (GO:0071173)2.92827588
102mitotic spindle assembly checkpoint (GO:0007094)2.92698031
103translational elongation (GO:0006414)2.92693392
104translesion synthesis (GO:0019985)2.91283955
105protein deneddylation (GO:0000338)2.91043289
106histone H2A acetylation (GO:0043968)2.90885055
107somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.90805671
108somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.90805671
109isotype switching (GO:0045190)2.90805671
110transcription elongation from RNA polymerase III promoter (GO:0006385)2.90469018
111termination of RNA polymerase III transcription (GO:0006386)2.90469018
112spliceosomal snRNP assembly (GO:0000387)2.90239380
113regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.89971229
114tRNA metabolic process (GO:0006399)2.89950986
115recombinational repair (GO:0000725)2.89112073
116rRNA modification (GO:0000154)2.88690234
117double-strand break repair via homologous recombination (GO:0000724)2.88616546
118regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.88510277
119pteridine-containing compound biosynthetic process (GO:0042559)2.87281786
120regulation of helicase activity (GO:0051095)2.86299311
121deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.86178520
122mitotic spindle checkpoint (GO:0071174)2.86016335
123ribonucleoprotein complex disassembly (GO:0032988)2.85707817
124postreplication repair (GO:0006301)2.85035676
125nuclear envelope organization (GO:0006998)2.84308641
126regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.84033737
127regulation of mitotic spindle organization (GO:0060236)2.83886447
128nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.83651770
129negative regulation of DNA-dependent DNA replication (GO:2000104)2.83351568
130regulation of mitotic metaphase/anaphase transition (GO:0030071)2.83046624
131ribosomal small subunit biogenesis (GO:0042274)2.82904297
132tetrahydrofolate metabolic process (GO:0046653)2.82453808
133DNA ligation (GO:0006266)2.82213041
134folic acid-containing compound metabolic process (GO:0006760)2.81175396
135transcription-coupled nucleotide-excision repair (GO:0006283)2.81065154
136positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.81064448
137peptidyl-arginine omega-N-methylation (GO:0035247)2.79832616
138anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.79579666
139RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.79483668
140tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.79483668
141establishment of integrated proviral latency (GO:0075713)2.79339993
142regulation of chromosome segregation (GO:0051983)2.78214796
143pre-miRNA processing (GO:0031054)2.76899139
144mitochondrial DNA replication (GO:0006264)2.75253804
145mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.74880762
146ncRNA metabolic process (GO:0034660)2.74848463
147DNA double-strand break processing (GO:0000729)2.74734924
148positive regulation of chromosome segregation (GO:0051984)2.74427733
149ubiquinone metabolic process (GO:0006743)2.74242435
150mismatch repair (GO:0006298)2.74028272

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.10112218
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.29243188
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.84466077
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.63358760
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.39316701
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.13899523
7* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.06601526
8* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.87428532
9* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.81632934
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.80595263
11* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.74775405
12* ETS1_20019798_ChIP-Seq_JURKAT_Human2.63623229
13* EST1_17652178_ChIP-ChIP_JURKAT_Human2.59280727
14* CREB1_15753290_ChIP-ChIP_HEK293T_Human2.41489642
15GABP_17652178_ChIP-ChIP_JURKAT_Human2.39735489
16ZNF274_21170338_ChIP-Seq_K562_Hela2.28707910
17AR_21909140_ChIP-Seq_LNCAP_Human2.27186123
18NELFA_20434984_ChIP-Seq_ESCs_Mouse2.22652356
19MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.20575173
20* XRN2_22483619_ChIP-Seq_HELA_Human2.17680332
21E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.08777403
22HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.02182762
23* VDR_23849224_ChIP-Seq_CD4+_Human2.00014312
24E2F1_18555785_ChIP-Seq_MESCs_Mouse1.99667821
25DCP1A_22483619_ChIP-Seq_HELA_Human1.99315820
26* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.96075591
27NANOG_18555785_ChIP-Seq_MESCs_Mouse1.95308094
28E2F1_21310950_ChIP-Seq_MCF-7_Human1.95103888
29* FOXP3_21729870_ChIP-Seq_TREG_Human1.93846868
30CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.90129912
31MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.83497486
32ELF1_17652178_ChIP-ChIP_JURKAT_Human1.78313189
33GABP_19822575_ChIP-Seq_HepG2_Human1.78147947
34POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.75965187
35PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.73515251
36* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.65418242
37HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.65254825
38STAT3_1855785_ChIP-Seq_MESCs_Mouse1.64430669
39YY1_21170310_ChIP-Seq_MESCs_Mouse1.64152458
40* TTF2_22483619_ChIP-Seq_HELA_Human1.62623343
41* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.61627396
42MYC_22102868_ChIP-Seq_BL_Human1.60750486
43* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.59739552
44SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.59580087
45NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.58668212
46VDR_22108803_ChIP-Seq_LS180_Human1.57974272
47CIITA_25753668_ChIP-Seq_RAJI_Human1.57253581
48* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.56651615
49YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.55338987
50SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.53246184
51SALL1_21062744_ChIP-ChIP_HESCs_Human1.53128649
52EWS_26573619_Chip-Seq_HEK293_Human1.52735638
53HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.49775507
54EGR1_19374776_ChIP-ChIP_THP-1_Human1.46213559
55TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.45743203
56FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.45336292
57SRF_21415370_ChIP-Seq_HL-1_Mouse1.45313612
58MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.42558822
59KDM5A_27292631_Chip-Seq_BREAST_Human1.38375985
60ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.36630215
61HOXB4_20404135_ChIP-ChIP_EML_Mouse1.31978790
62KLF4_18555785_ChIP-Seq_MESCs_Mouse1.31813834
63POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.30721528
64SOX2_18555785_ChIP-Seq_MESCs_Mouse1.27484577
65SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.26667880
66FUS_26573619_Chip-Seq_HEK293_Human1.25084696
67IRF1_19129219_ChIP-ChIP_H3396_Human1.24628628
68NOTCH1_21737748_ChIP-Seq_TLL_Human1.22785102
69DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.20997303
70IGF1R_20145208_ChIP-Seq_DFB_Human1.18338765
71* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.16843181
72DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.16403576
73TP63_19390658_ChIP-ChIP_HaCaT_Human1.16158455
74ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.15881512
75MYC_18940864_ChIP-ChIP_HL60_Human1.15485118
76FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.15357620
77ELK1_19687146_ChIP-ChIP_HELA_Human1.13355109
78ERG_20887958_ChIP-Seq_HPC-7_Mouse1.11990337
79GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10762664
80E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.08927477
81* TFEB_21752829_ChIP-Seq_HELA_Human1.05846848
82PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.04201937
83NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.02055811
84CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.01865099
85CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01496348
86BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.00398648
87NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.98168676
88KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.98068190
89VDR_21846776_ChIP-Seq_THP-1_Human0.97383886
90RBPJ_22232070_ChIP-Seq_NCS_Mouse0.95007312
91TCF3_18692474_ChIP-Seq_MEFs_Mouse0.94892011
92FLI1_27457419_Chip-Seq_LIVER_Mouse0.94830175
93KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.94444607
94HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.93676394
95TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.92271345
96POU3F2_20337985_ChIP-ChIP_501MEL_Human0.92014759
97* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.91724749
98ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.90452131
99PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.90010115
100NANOG_21062744_ChIP-ChIP_HESCs_Human0.89934948
101CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.89004526
102CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.87832261
103PADI4_21655091_ChIP-ChIP_MCF-7_Human0.86946890
104SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.86943954
105EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.86813059
106* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.86807324
107GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.86288128
108* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.86236521
109NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.85662217
110PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.85439544
111ELK1_22589737_ChIP-Seq_MCF10A_Human0.85009674
112TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.84925428
113SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.84857337
114OCT4_18692474_ChIP-Seq_MEFs_Mouse0.83472146
115SOX2_18692474_ChIP-Seq_MEFs_Mouse0.82811907
116SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.82747725
117NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.81871220
118TAF15_26573619_Chip-Seq_HEK293_Human0.79542369
119NANOG_16153702_ChIP-ChIP_HESCs_Human0.79492132
120FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.78641994
121TP53_22573176_ChIP-Seq_HFKS_Human0.78376715
122SOX2_16153702_ChIP-ChIP_HESCs_Human0.78127134
123CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.77847274
124POU5F1_16153702_ChIP-ChIP_HESCs_Human0.73646038
125* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.69809622
126PCGF2_27294783_Chip-Seq_ESCs_Mouse0.69200079
127HTT_18923047_ChIP-ChIP_STHdh_Human0.68606206

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.37918135
2MP0010094_abnormal_chromosome_stability4.38124720
3MP0003111_abnormal_nucleus_morphology4.38070306
4MP0004957_abnormal_blastocyst_morpholog3.87597028
5MP0003077_abnormal_cell_cycle3.85839081
6MP0008057_abnormal_DNA_replication3.61903419
7MP0008058_abnormal_DNA_repair3.02020449
8MP0003806_abnormal_nucleotide_metabolis2.77575150
9MP0003646_muscle_fatigue2.47332050
10MP0008007_abnormal_cellular_replicative2.46303438
11MP0001730_embryonic_growth_arrest2.21016464
12MP0008932_abnormal_embryonic_tissue2.16569774
13MP0003718_maternal_effect2.15000831
14MP0003123_paternal_imprinting2.12572318
15MP0002396_abnormal_hematopoietic_system1.88334926
16MP0000350_abnormal_cell_proliferation1.87273641
17* MP0005380_embryogenesis_phenotype1.86429694
18* MP0001672_abnormal_embryogenesis/_devel1.86429694
19MP0008995_early_reproductive_senescence1.76672182
20MP0003984_embryonic_growth_retardation1.75821894
21MP0002088_abnormal_embryonic_growth/wei1.71560309
22MP0000490_abnormal_crypts_of1.70493741
23MP0010307_abnormal_tumor_latency1.68852475
24MP0006292_abnormal_olfactory_placode1.67306236
25MP0005645_abnormal_hypothalamus_physiol1.66151148
26MP0001697_abnormal_embryo_size1.64312292
27MP0010352_gastrointestinal_tract_polyps1.62373979
28MP0003786_premature_aging1.60975770
29MP0005075_abnormal_melanosome_morpholog1.59178020
30MP0003567_abnormal_fetal_cardiomyocyte1.56955341
31* MP0002080_prenatal_lethality1.52633744
32MP0005174_abnormal_tail_pigmentation1.49062848
33MP0000372_irregular_coat_pigmentation1.47055920
34MP0002822_catalepsy1.46534967
35MP0008877_abnormal_DNA_methylation1.45728448
36MP0003186_abnormal_redox_activity1.45253148
37MP0002938_white_spotting1.43074259
38MP0002085_abnormal_embryonic_tissue1.41751826
39MP0002086_abnormal_extraembryonic_tissu1.40889678
40MP0006036_abnormal_mitochondrial_physio1.39663741
41MP0006072_abnormal_retinal_apoptosis1.37532006
42MP0010030_abnormal_orbit_morphology1.37325439
43MP0000569_abnormal_digit_pigmentation1.36450292
44MP0000313_abnormal_cell_death1.36315297
45MP0002084_abnormal_developmental_patter1.31984059
46MP0002009_preneoplasia1.29532598
47MP0002837_dystrophic_cardiac_calcinosis1.28438200
48MP0001529_abnormal_vocalization1.27873191
49MP0002019_abnormal_tumor_incidence1.26370906
50MP0002653_abnormal_ependyma_morphology1.24073267
51MP0005397_hematopoietic_system_phenotyp1.21874585
52MP0001545_abnormal_hematopoietic_system1.21874585
53MP0003119_abnormal_digestive_system1.20867307
54MP0009333_abnormal_splenocyte_physiolog1.20683645
55MP0003656_abnormal_erythrocyte_physiolo1.20522517
56MP0002210_abnormal_sex_determination1.15869744
57MP0000015_abnormal_ear_pigmentation1.14381110
58MP0005266_abnormal_metabolism1.11904100
59MP0004808_abnormal_hematopoietic_stem1.10856594
60MP0001853_heart_inflammation1.10558940
61MP0004197_abnormal_fetal_growth/weight/1.07678109
62MP0005670_abnormal_white_adipose1.07128447
63MP0003221_abnormal_cardiomyocyte_apopto1.07087216
64MP0006035_abnormal_mitochondrial_morpho1.05699286
65MP0004145_abnormal_muscle_electrophysio1.01593507
66* MP0009840_abnormal_foam_cell1.00885805
67MP0004084_abnormal_cardiac_muscle1.00406427
68MP0005360_urolithiasis0.99632869
69MP0001145_abnormal_male_reproductive0.99025977
70MP0000358_abnormal_cell_content/0.98011646
71MP0002234_abnormal_pharynx_morphology0.97971189
72MP0005084_abnormal_gallbladder_morpholo0.97630004
73MP0001119_abnormal_female_reproductive0.97069545
74MP0005253_abnormal_eye_physiology0.96284985
75MP0002736_abnormal_nociception_after0.96182947
76MP0003787_abnormal_imprinting0.96130281
77MP0003705_abnormal_hypodermis_morpholog0.95067463
78MP0008789_abnormal_olfactory_epithelium0.94459396
79MP0001188_hyperpigmentation0.92265484
80* MP0001929_abnormal_gametogenesis0.92260361
81MP0005085_abnormal_gallbladder_physiolo0.91976116
82MP0001293_anophthalmia0.91802384
83MP0004233_abnormal_muscle_weight0.90401901
84MP0000653_abnormal_sex_gland0.89529944
85MP0008875_abnormal_xenobiotic_pharmacok0.88952017
86MP0009697_abnormal_copulation0.87818637
87MP0003315_abnormal_perineum_morphology0.87382338
88MP0005551_abnormal_eye_electrophysiolog0.85381414
89MP0003698_abnormal_male_reproductive0.84371402
90MP0004215_abnormal_myocardial_fiber0.83354576
91MP0000689_abnormal_spleen_morphology0.81796114
92MP0005187_abnormal_penis_morphology0.80659842
93MP0000371_diluted_coat_color0.80442795
94MP0009672_abnormal_birth_weight0.80359949
95MP0001727_abnormal_embryo_implantation0.80197584
96MP0001915_intracranial_hemorrhage0.79457933
97MP0000631_abnormal_neuroendocrine_gland0.78494298
98MP0003763_abnormal_thymus_physiology0.78374079
99* MP0002722_abnormal_immune_system0.77970035
100* MP0002269_muscular_atrophy0.77707110
101MP0005646_abnormal_pituitary_gland0.77704907
102* MP0002102_abnormal_ear_morphology0.77546940
103MP0004147_increased_porphyrin_level0.76661400
104MP0003699_abnormal_female_reproductive0.74349204
105MP0000858_altered_metastatic_potential0.73797409
106* MP0002398_abnormal_bone_marrow0.73796395
107MP0005330_cardiomyopathy0.72738652
108MP0005076_abnormal_cell_differentiation0.71274093
109MP0005391_vision/eye_phenotype0.70641435
110MP0003937_abnormal_limbs/digits/tail_de0.70522156
111* MP0000703_abnormal_thymus_morphology0.70393691
112MP0005384_cellular_phenotype0.70212581
113MP0003121_genomic_imprinting0.69771524
114MP0005621_abnormal_cell_physiology0.69371163
115MP0010630_abnormal_cardiac_muscle0.69293538
116MP0002638_abnormal_pupillary_reflex0.68875317
117MP0003950_abnormal_plasma_membrane0.68352601
118MP0002095_abnormal_skin_pigmentation0.67269406
119MP0008872_abnormal_physiological_respon0.66320145
120MP0005365_abnormal_bile_salt0.66206936
121MP0003890_abnormal_embryonic-extraembry0.65824457
122MP0005319_abnormal_enzyme/_coenzyme0.65809805
123MP0008775_abnormal_heart_ventricle0.64967698
124MP0001286_abnormal_eye_development0.64833199
125MP0000427_abnormal_hair_cycle0.64140366
126MP0001764_abnormal_homeostasis0.63769616
127MP0002163_abnormal_gland_morphology0.62971912
128MP0005451_abnormal_body_composition0.62850443
129MP0001968_abnormal_touch/_nociception0.62548024
130MP0002075_abnormal_coat/hair_pigmentati0.62278455
131MP0000750_abnormal_muscle_regeneration0.62186488
132MP0004381_abnormal_hair_follicle0.61430241
133MP0001661_extended_life_span0.61344651
134MP0000598_abnormal_liver_morphology0.61230850
135* MP0002429_abnormal_blood_cell0.60953015
136MP0002160_abnormal_reproductive_system0.60706182
137* MP0000647_abnormal_sebaceous_gland0.59817061
138MP0003137_abnormal_impulse_conducting0.59777767
139MP0003943_abnormal_hepatobiliary_system0.59179370
140MP0009046_muscle_twitch0.58729081
141MP0005395_other_phenotype0.58603781
142MP0000266_abnormal_heart_morphology0.58443254
143MP0002111_abnormal_tail_morphology0.57072652
144MP0005023_abnormal_wound_healing0.56177156

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)4.92445018
2Birth length less than 3rd percentile (HP:0003561)4.67011549
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.25159055
4Chromsome breakage (HP:0040012)4.14399799
5Breast hypoplasia (HP:0003187)4.12973026
6Acute necrotizing encephalopathy (HP:0006965)3.59397578
7Oral leukoplakia (HP:0002745)3.51076724
8Abnormal mitochondria in muscle tissue (HP:0008316)3.47416190
9Increased CSF lactate (HP:0002490)3.44137343
10Acute encephalopathy (HP:0006846)3.38940867
11Abnormality of pyrimidine metabolism (HP:0004353)3.33977633
12Selective tooth agenesis (HP:0001592)3.19477539
13Abnormality of the preputium (HP:0100587)3.17707931
14Colon cancer (HP:0003003)3.15783464
15Multiple enchondromatosis (HP:0005701)3.11063144
16Absent thumb (HP:0009777)3.10582856
17Increased hepatocellular lipid droplets (HP:0006565)3.09907995
18Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.08453453
19Abnormality of alanine metabolism (HP:0010916)3.08453453
20Hyperalaninemia (HP:0003348)3.08453453
21Abnormality of chromosome stability (HP:0003220)3.07831411
22Mitochondrial inheritance (HP:0001427)3.07632980
23Meckel diverticulum (HP:0002245)3.07290624
24Ependymoma (HP:0002888)3.01720355
25Impulsivity (HP:0100710)3.00500103
26Progressive macrocephaly (HP:0004481)2.95700674
27Lipid accumulation in hepatocytes (HP:0006561)2.94389018
28Carpal bone hypoplasia (HP:0001498)2.93300417
29Abnormality of the ileum (HP:0001549)2.92703866
30Medulloblastoma (HP:0002885)2.90789112
31Aplasia/Hypoplasia of the uvula (HP:0010293)2.86291362
32Patellar aplasia (HP:0006443)2.85871431
33Aplasia/Hypoplasia of the patella (HP:0006498)2.77952882
34Cerebral edema (HP:0002181)2.77304163
35Abnormality of cells of the erythroid lineage (HP:0012130)2.76849279
36Rough bone trabeculation (HP:0100670)2.74572275
37Duplicated collecting system (HP:0000081)2.74247270
38Absent radius (HP:0003974)2.74101965
39Degeneration of anterior horn cells (HP:0002398)2.69552067
40Abnormality of the anterior horn cell (HP:0006802)2.69552067
41Lactic acidosis (HP:0003128)2.66308277
42Hepatocellular necrosis (HP:0001404)2.65456181
43Abnormal number of erythroid precursors (HP:0012131)2.61839375
44Aplastic anemia (HP:0001915)2.61810664
45Myelodysplasia (HP:0002863)2.55362680
46Rhabdomyosarcoma (HP:0002859)2.52858393
47Aplasia involving forearm bones (HP:0009822)2.52363864
48Absent forearm bone (HP:0003953)2.52363864
49Microretrognathia (HP:0000308)2.51366325
50Pancreatic cysts (HP:0001737)2.46692346
51Thrombocytosis (HP:0001894)2.44094308
52Pallor (HP:0000980)2.43712290
53Reduced antithrombin III activity (HP:0001976)2.41817647
54Hyperglycinuria (HP:0003108)2.40432900
55Aplasia/Hypoplasia of the sacrum (HP:0008517)2.39260153
56Bone marrow hypocellularity (HP:0005528)2.38876735
57Secondary amenorrhea (HP:0000869)2.38543992
58Horseshoe kidney (HP:0000085)2.37843112
59Increased intramyocellular lipid droplets (HP:0012240)2.37773334
60Premature ovarian failure (HP:0008209)2.35974802
61Ectopic kidney (HP:0000086)2.35944020
62Abnormality of the renal collecting system (HP:0004742)2.33314187
63Ureteral duplication (HP:0000073)2.32281774
64Tongue fasciculations (HP:0001308)2.30642925
65Abnormality of the pons (HP:0007361)2.30056236
66Albinism (HP:0001022)2.28349981
67Macrocytic anemia (HP:0001972)2.28037421
68Abnormal protein N-linked glycosylation (HP:0012347)2.27489317
69Abnormal protein glycosylation (HP:0012346)2.27489317
70Abnormal glycosylation (HP:0012345)2.27489317
71Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.27489317
72Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.27369113
73Decreased activity of mitochondrial respiratory chain (HP:0008972)2.27369113
74Pancreatic fibrosis (HP:0100732)2.24436290
75Muscle fibrillation (HP:0010546)2.21908359
76Increased serum pyruvate (HP:0003542)2.21772465
77Agnosia (HP:0010524)2.21683583
78Hypoplasia of the pons (HP:0012110)2.21307301
79Hyperglycinemia (HP:0002154)2.21190271
80Methylmalonic acidemia (HP:0002912)2.20169319
81Small intestinal stenosis (HP:0012848)2.18818470
82Duodenal stenosis (HP:0100867)2.18818470
83Supernumerary spleens (HP:0009799)2.18054206
84Increased serum lactate (HP:0002151)2.16617747
85Glioma (HP:0009733)2.16048952
86Neoplasm of the oral cavity (HP:0100649)2.16011602
87Abnormality of glycolysis (HP:0004366)2.14806789
88Sloping forehead (HP:0000340)2.12711417
89Abnormality of midbrain morphology (HP:0002418)2.12120478
90Molar tooth sign on MRI (HP:0002419)2.12120478
91Abnormality of reticulocytes (HP:0004312)2.11827325
92Short thumb (HP:0009778)2.11765036
93Abnormality of aspartate family amino acid metabolism (HP:0010899)2.08927546
94Premature graying of hair (HP:0002216)2.08659063
95Abnormality of serum amino acid levels (HP:0003112)2.08071559
96Renal cortical cysts (HP:0000803)2.07763677
97Exercise intolerance (HP:0003546)2.06905074
98Abnormality of the labia minora (HP:0012880)2.06721679
99Neoplasm of the adrenal gland (HP:0100631)2.03490024
100Neoplasm of the pancreas (HP:0002894)2.02796293
101Methylmalonic aciduria (HP:0012120)2.02229225
102Neoplasm of the adrenal cortex (HP:0100641)2.01918777
103Tracheoesophageal fistula (HP:0002575)2.01703075
104Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.01429218
105Type II lissencephaly (HP:0007260)2.01335382
106Abnormality of DNA repair (HP:0003254)2.01273060
107Abnormality of the astrocytes (HP:0100707)2.01116967
108Astrocytoma (HP:0009592)2.01116967
109Neoplasm of striated muscle (HP:0009728)1.99776469
110Amaurosis fugax (HP:0100576)1.99756993
111Type I transferrin isoform profile (HP:0003642)1.99127389
112Glossoptosis (HP:0000162)1.95054802
113Abnormal spermatogenesis (HP:0008669)1.91764891
114Abnormality of the carotid arteries (HP:0005344)1.91386131
115Cellular immunodeficiency (HP:0005374)1.91379089
116Cerebral hypomyelination (HP:0006808)1.91346551
117Optic disc pallor (HP:0000543)1.91213349
118Trismus (HP:0000211)1.91178978
119Lethargy (HP:0001254)1.90022125
120Triphalangeal thumb (HP:0001199)1.90021041
121Progressive muscle weakness (HP:0003323)1.89105550
122Abnormality of glycine metabolism (HP:0010895)1.89067786
123Abnormality of serine family amino acid metabolism (HP:0010894)1.89067786
124Abnormality of methionine metabolism (HP:0010901)1.86955015
125Aplasia/Hypoplasia of the sternum (HP:0006714)1.86643125
126Increased muscle lipid content (HP:0009058)1.86358381
127Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.85784629
128Rhabdomyolysis (HP:0003201)1.85698240
129Abnormality of the duodenum (HP:0002246)1.85496418
130Nausea (HP:0002018)1.84716064
131Neoplasm of the colon (HP:0100273)1.84388842
132Pancytopenia (HP:0001876)1.84351826
133Microvesicular hepatic steatosis (HP:0001414)1.84217482
134Megaloblastic anemia (HP:0001889)1.83623700
135Cafe-au-lait spot (HP:0000957)1.83184539
136Progressive inability to walk (HP:0002505)1.82342694
137Basal cell carcinoma (HP:0002671)1.81317664
138Respiratory failure (HP:0002878)1.80791628
139Hepatic necrosis (HP:0002605)1.80168322
140Renal Fanconi syndrome (HP:0001994)1.79183143
14111 pairs of ribs (HP:0000878)1.79043027
142Pendular nystagmus (HP:0012043)1.78355357
143CNS hypomyelination (HP:0003429)1.77770802
144Decreased electroretinogram (ERG) amplitude (HP:0000654)1.77375031
145Clubbing of toes (HP:0100760)1.77373612
146True hermaphroditism (HP:0010459)1.76811251
147Hyperammonemia (HP:0001987)1.76542584
148Abnormal number of incisors (HP:0011064)1.76426703
149Progressive microcephaly (HP:0000253)1.73676040
150Cerebellar dysplasia (HP:0007033)1.72926699
1513-Methylglutaconic aciduria (HP:0003535)1.72712116
152Retinal dysplasia (HP:0007973)1.72135869
153Leukodystrophy (HP:0002415)1.70954114
154Abnormality of the renal cortex (HP:0011035)1.70917971
155Sclerocornea (HP:0000647)1.68825285
156CNS demyelination (HP:0007305)1.65930177
157Attenuation of retinal blood vessels (HP:0007843)1.64042199
158Volvulus (HP:0002580)1.62226190
159Prominent metopic ridge (HP:0005487)1.61605678
160Progressive external ophthalmoplegia (HP:0000590)1.61472146

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EIF2AK16.08781955
2BUB13.90233026
3WEE13.82753645
4TLK13.50464850
5CDC73.15286861
6ACVR1B2.77765314
7NEK22.65526976
8NEK12.54261631
9STK162.50353213
10TTK2.32953833
11PBK2.31100808
12NME22.27016674
13SRPK12.25203121
14MST42.22901325
15TRIM282.20521745
16NUAK12.11971616
17VRK22.06001613
18MAP4K21.99657746
19DYRK31.81093307
20BCKDK1.80210051
21PLK11.74602277
22PLK41.71833572
23BRSK21.64426381
24MAP3K41.54137206
25FLT31.54054435
26TSSK61.51589290
27PKN21.49404326
28AURKB1.47346088
29CDK71.44872759
30TGFBR11.43814419
31CDK41.43479389
32ATR1.41634972
33RPS6KA41.39917276
34ZAK1.39361956
35EEF2K1.38595484
36RPS6KB21.38279315
37BMPR1B1.30894855
38NME11.30591218
39MAP3K81.29591617
40EPHA21.28050913
41CSNK1G11.23546718
42STK38L1.15631490
43CHEK21.15129183
44BRD41.13844597
45FRK1.13837078
46CDK121.13703744
47CSNK1G31.11527664
48EIF2AK31.10000063
49STK101.08470550
50PDK31.08418003
51PDK41.08418003
52MAP2K31.07539433
53VRK11.06062527
54WNK41.05948474
55PLK31.05248215
56STK391.04307269
57WNK31.02926879
58MAP3K101.01265250
59AURKA1.00881911
60PASK1.00235600
61BCR0.99300409
62CSNK1A1L0.99259870
63ERBB30.99140262
64TAF10.98565555
65CLK10.98047033
66INSRR0.97512397
67MAP3K90.93139622
68CHEK10.92218433
69SCYL20.91802380
70MAP2K70.90762446
71BRAF0.88178646
72CSNK1G20.87917322
73PIM10.87353613
74LATS20.83975132
75RAF10.83517134
76GRK10.81544496
77TAOK20.77685330
78MAP2K60.75812581
79BRSK10.74385854
80ATM0.73205375
81CDK20.70420321
82STK40.69841907
83MKNK20.66168380
84PDK20.65389232
85PAK40.65004575
86PNCK0.63752369
87ADRBK20.63279554
88OBSCN0.62542065
89ALK0.60700020
90CDK30.60391668
91TEC0.60120666
92DAPK10.59383863
93CSNK1E0.59162508
94STK30.58696381
95MAPK130.57033979
96MKNK10.56677114
97MAPK110.56483106
98MAP3K60.55849077
99MAPKAPK50.55813031
100AKT20.54930142
101TAOK30.53739845
102MOS0.53111758
103MAP4K10.52661575
104ERBB40.52362650
105CDK80.51256389
106KDR0.50642289
107MELK0.50434339
108TNIK0.50247071
109CCNB10.49876365
110TESK20.49495050
111PIM20.49453418
112MAP3K30.49161707
113MTOR0.48688035
114TAOK10.48138446
115CSNK2A20.47582643
116PAK10.47471630
117CDK90.46919756
118KSR10.46455358
119EIF2AK20.45579708
120ARAF0.45378154
121CSNK2A10.44755753
122PRKCI0.44543530
123CDK10.44248632
124PINK10.43974825
125MAPKAPK30.43627401
126CSNK1D0.43521493
127LRRK20.41640170
128MAP3K110.40696670
129OXSR10.40523560
130TRIB30.39784939
131LMTK20.38297456
132TTN0.36131116
133JAK30.36058224
134NLK0.35807605
135PHKG10.35622963
136PHKG20.35622963
137CDK60.32383868
138PRKDC0.32293165
139MAP3K50.31907574
140DYRK20.30718815
141RPS6KA50.30190042
142PLK20.30094433
143ZAP700.29798923
144PRKCG0.29426191
145LATS10.27515952

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.58676353
2Mismatch repair_Homo sapiens_hsa034303.69550354
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.47109089
4One carbon pool by folate_Homo sapiens_hsa006702.99609659
5RNA polymerase_Homo sapiens_hsa030202.98436896
6Base excision repair_Homo sapiens_hsa034102.94042121
7Ribosome_Homo sapiens_hsa030102.86499899
8RNA transport_Homo sapiens_hsa030132.83339726
9Spliceosome_Homo sapiens_hsa030402.72037099
10Cell cycle_Homo sapiens_hsa041102.60791818
11Homologous recombination_Homo sapiens_hsa034402.58474977
12Proteasome_Homo sapiens_hsa030502.48754059
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.48712584
14Protein export_Homo sapiens_hsa030602.43465968
15Pyrimidine metabolism_Homo sapiens_hsa002402.35513015
16Nucleotide excision repair_Homo sapiens_hsa034202.28443957
17Fanconi anemia pathway_Homo sapiens_hsa034602.11322070
18Oxidative phosphorylation_Homo sapiens_hsa001902.03977644
19Parkinsons disease_Homo sapiens_hsa050121.94725427
20RNA degradation_Homo sapiens_hsa030181.74342757
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.73462025
22Biosynthesis of amino acids_Homo sapiens_hsa012301.72776505
232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.69017716
24p53 signaling pathway_Homo sapiens_hsa041151.64609247
25Vitamin B6 metabolism_Homo sapiens_hsa007501.61922657
26Cysteine and methionine metabolism_Homo sapiens_hsa002701.46923539
27Basal transcription factors_Homo sapiens_hsa030221.44294719
28Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.42768203
29Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.40061136
30mRNA surveillance pathway_Homo sapiens_hsa030151.38451787
31Folate biosynthesis_Homo sapiens_hsa007901.38020301
32Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.36155575
33Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.31067632
34Carbon metabolism_Homo sapiens_hsa012001.30689591
35Fatty acid elongation_Homo sapiens_hsa000621.29395162
36Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.27018750
37Sulfur relay system_Homo sapiens_hsa041221.26263233
38Purine metabolism_Homo sapiens_hsa002301.25942377
39Pentose phosphate pathway_Homo sapiens_hsa000301.25342136
40Drug metabolism - other enzymes_Homo sapiens_hsa009831.21823244
41Selenocompound metabolism_Homo sapiens_hsa004501.21174134
42Butanoate metabolism_Homo sapiens_hsa006501.21002992
43Cyanoamino acid metabolism_Homo sapiens_hsa004601.19943572
44Non-homologous end-joining_Homo sapiens_hsa034501.07944818
45Systemic lupus erythematosus_Homo sapiens_hsa053221.05970068
46Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.97097784
47Alzheimers disease_Homo sapiens_hsa050100.96367582
48Steroid biosynthesis_Homo sapiens_hsa001000.96299820
49Epstein-Barr virus infection_Homo sapiens_hsa051690.96031018
50Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.93632300
51Nitrogen metabolism_Homo sapiens_hsa009100.92462520
52Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.91701192
53Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.91035844
54Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.88812266
55Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.87451025
56Arginine and proline metabolism_Homo sapiens_hsa003300.87305916
57Phototransduction_Homo sapiens_hsa047440.86404387
58Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.86259705
59Fatty acid degradation_Homo sapiens_hsa000710.85754127
60Herpes simplex infection_Homo sapiens_hsa051680.83314351
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.79618486
62Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.77323397
63Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.70700546
64Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.69885382
65Propanoate metabolism_Homo sapiens_hsa006400.69283739
66Oocyte meiosis_Homo sapiens_hsa041140.68864388
67Pyruvate metabolism_Homo sapiens_hsa006200.66770506
68Fructose and mannose metabolism_Homo sapiens_hsa000510.65954326
69Viral carcinogenesis_Homo sapiens_hsa052030.64972525
70Vitamin digestion and absorption_Homo sapiens_hsa049770.63077984
71beta-Alanine metabolism_Homo sapiens_hsa004100.62565857
72Regulation of autophagy_Homo sapiens_hsa041400.62434957
73Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.60685461
74Glutathione metabolism_Homo sapiens_hsa004800.60296006
75Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.57350491
76Cardiac muscle contraction_Homo sapiens_hsa042600.56135586
77Thyroid cancer_Homo sapiens_hsa052160.54340307
78Lysine degradation_Homo sapiens_hsa003100.53488287
79Maturity onset diabetes of the young_Homo sapiens_hsa049500.52139323
80HTLV-I infection_Homo sapiens_hsa051660.47081962
81Pentose and glucuronate interconversions_Homo sapiens_hsa000400.45963259
82Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.44797520
83Galactose metabolism_Homo sapiens_hsa000520.42817353
84Arginine biosynthesis_Homo sapiens_hsa002200.40256785
85Retinol metabolism_Homo sapiens_hsa008300.39442455
86Metabolic pathways_Homo sapiens_hsa011000.38997477
87Antigen processing and presentation_Homo sapiens_hsa046120.38873939
88Legionellosis_Homo sapiens_hsa051340.38457881
89Olfactory transduction_Homo sapiens_hsa047400.38105009
90Small cell lung cancer_Homo sapiens_hsa052220.37369108
91Fatty acid metabolism_Homo sapiens_hsa012120.35163716
92Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.34762328
93Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.34139331
94Peroxisome_Homo sapiens_hsa041460.33907571
95Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.33326052
96Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.32945041
97Huntingtons disease_Homo sapiens_hsa050160.30810563
98MicroRNAs in cancer_Homo sapiens_hsa052060.30718120
99Transcriptional misregulation in cancer_Homo sapiens_hsa052020.30456137
100Sulfur metabolism_Homo sapiens_hsa009200.29112392
101Tryptophan metabolism_Homo sapiens_hsa003800.27836613
102Circadian rhythm_Homo sapiens_hsa047100.27431521
103Influenza A_Homo sapiens_hsa051640.21415390
104N-Glycan biosynthesis_Homo sapiens_hsa005100.20990355
105Central carbon metabolism in cancer_Homo sapiens_hsa052300.20616899
106Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.20005508
107Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.19843786
108HIF-1 signaling pathway_Homo sapiens_hsa040660.18598995
109Caffeine metabolism_Homo sapiens_hsa002320.18237102
110SNARE interactions in vesicular transport_Homo sapiens_hsa041300.18133750
111Primary bile acid biosynthesis_Homo sapiens_hsa001200.16825892
112Alcoholism_Homo sapiens_hsa050340.16156490
113Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.15472765
114AMPK signaling pathway_Homo sapiens_hsa041520.15068718
115Hippo signaling pathway_Homo sapiens_hsa043900.14096225
116Fat digestion and absorption_Homo sapiens_hsa049750.13786371
117Apoptosis_Homo sapiens_hsa042100.13699605
118mTOR signaling pathway_Homo sapiens_hsa041500.13626651
119Hepatitis B_Homo sapiens_hsa051610.12995802
120NF-kappa B signaling pathway_Homo sapiens_hsa040640.12891810
121Acute myeloid leukemia_Homo sapiens_hsa052210.11470727
122TGF-beta signaling pathway_Homo sapiens_hsa043500.11301992
123Measles_Homo sapiens_hsa051620.10937011
124Colorectal cancer_Homo sapiens_hsa052100.10733374
125Linoleic acid metabolism_Homo sapiens_hsa005910.10703973
126Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.10237120
127FoxO signaling pathway_Homo sapiens_hsa040680.09428536
128alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.08951284

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