SURF2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene shares a bidirectional promoter with surfeit 1 (SURF1; GeneID: 6834), which is located on the opposite strand. It encodes a conserved protein that is expressed in a variety of tissues. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1chaperone-mediated protein transport (GO:0072321)6.07490141
2maturation of SSU-rRNA (GO:0030490)5.99761102
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.40727803
4ATP synthesis coupled proton transport (GO:0015986)5.40727803
5ribosomal large subunit biogenesis (GO:0042273)5.12126357
6viral transcription (GO:0019083)5.10772962
7ribosomal small subunit biogenesis (GO:0042274)5.08967701
8ribosomal small subunit assembly (GO:0000028)5.02620462
9translational termination (GO:0006415)5.01240746
10mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.96211305
11DNA deamination (GO:0045006)4.89217219
12transcription elongation from RNA polymerase I promoter (GO:0006362)4.81513624
13respiratory electron transport chain (GO:0022904)4.69592785
14electron transport chain (GO:0022900)4.59161218
15ribonucleoprotein complex biogenesis (GO:0022613)4.57970462
16termination of RNA polymerase I transcription (GO:0006363)4.55043097
17SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.47817126
18ribosome assembly (GO:0042255)4.47270011
19translational elongation (GO:0006414)4.45053533
20cotranslational protein targeting to membrane (GO:0006613)4.40080583
21translational initiation (GO:0006413)4.39063852
22protein targeting to ER (GO:0045047)4.36610784
23transcription elongation from RNA polymerase III promoter (GO:0006385)4.33892188
24termination of RNA polymerase III transcription (GO:0006386)4.33892188
25rRNA processing (GO:0006364)4.30938332
26DNA strand elongation involved in DNA replication (GO:0006271)4.30469945
27ribosome biogenesis (GO:0042254)4.27574916
28protein complex biogenesis (GO:0070271)4.26933009
29telomere maintenance via semi-conservative replication (GO:0032201)4.25548411
30pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.23458013
31formation of translation preinitiation complex (GO:0001731)4.20761297
32proteasome assembly (GO:0043248)4.19796237
33establishment of protein localization to endoplasmic reticulum (GO:0072599)4.19781435
34rRNA modification (GO:0000154)4.17935900
35rRNA metabolic process (GO:0016072)4.16381076
36mitochondrial respiratory chain complex I assembly (GO:0032981)4.13298126
37NADH dehydrogenase complex assembly (GO:0010257)4.13298126
38mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.13298126
39DNA strand elongation (GO:0022616)4.12224781
40mitochondrial respiratory chain complex assembly (GO:0033108)4.11111486
41protein localization to endoplasmic reticulum (GO:0070972)4.10286661
42transcription from RNA polymerase I promoter (GO:0006360)4.09561409
43nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.07461346
44spliceosomal snRNP assembly (GO:0000387)4.05959986
45translation (GO:0006412)4.05320130
46cullin deneddylation (GO:0010388)4.03552228
47L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.00921053
487-methylguanosine mRNA capping (GO:0006370)4.00098872
49purine nucleobase biosynthetic process (GO:0009113)3.98185194
50cellular protein complex disassembly (GO:0043624)3.95902304
51nucleobase biosynthetic process (GO:0046112)3.95668965
52cellular component biogenesis (GO:0044085)3.90895532
53establishment of integrated proviral latency (GO:0075713)3.90357875
547-methylguanosine RNA capping (GO:0009452)3.90225770
55RNA capping (GO:0036260)3.90225770
56viral life cycle (GO:0019058)3.89589584
57negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.88861724
58protein localization to mitochondrion (GO:0070585)3.85193160
59pseudouridine synthesis (GO:0001522)3.83525775
60DNA damage response, detection of DNA damage (GO:0042769)3.83112339
61transcription initiation from RNA polymerase I promoter (GO:0006361)3.79001207
62positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.77605258
63transcription-coupled nucleotide-excision repair (GO:0006283)3.75664219
64base-excision repair, AP site formation (GO:0006285)3.72488821
65telomere maintenance via recombination (GO:0000722)3.71668140
66protein deneddylation (GO:0000338)3.69651222
67protein neddylation (GO:0045116)3.68244112
68regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.68104685
69tRNA methylation (GO:0030488)3.66347166
70regulation of nuclear cell cycle DNA replication (GO:0033262)3.59133231
71establishment of protein localization to mitochondrial membrane (GO:0090151)3.58597859
72anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.57182591
73regulation of mitochondrial translation (GO:0070129)3.56328287
74negative regulation of ligase activity (GO:0051352)3.54557379
75negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.54557379
76signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.50455443
77signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.50455443
78signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.50455443
79DNA replication initiation (GO:0006270)3.49570779
80DNA replication checkpoint (GO:0000076)3.48406565
81respiratory chain complex IV assembly (GO:0008535)3.47879588
82signal transduction involved in DNA damage checkpoint (GO:0072422)3.46311104
83signal transduction involved in DNA integrity checkpoint (GO:0072401)3.46311104
84protein complex disassembly (GO:0043241)3.45565362
85establishment of viral latency (GO:0019043)3.45487168
86L-methionine biosynthetic process (GO:0071265)3.45114866
87amino acid salvage (GO:0043102)3.45114866
88L-methionine salvage (GO:0071267)3.45114866
89regulation of cellular amino acid metabolic process (GO:0006521)3.42816524
90signal transduction involved in cell cycle checkpoint (GO:0072395)3.41270474
91spliceosomal complex assembly (GO:0000245)3.40480954
92pyrimidine nucleotide catabolic process (GO:0006244)3.40419871
93regulation of mitotic spindle organization (GO:0060236)3.38321268
94guanosine-containing compound biosynthetic process (GO:1901070)3.37788298
95maturation of 5.8S rRNA (GO:0000460)3.37502490
96DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.36511814
97pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.36192726
98peptidyl-histidine modification (GO:0018202)3.35496381
99rRNA methylation (GO:0031167)3.34776328
100telomere maintenance via telomere lengthening (GO:0010833)3.33484836
101intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.33394071
102signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.33394071
103mitotic recombination (GO:0006312)3.32815910
104protein maturation by protein folding (GO:0022417)3.32040842
105DNA-templated transcription, termination (GO:0006353)3.31735557
106metallo-sulfur cluster assembly (GO:0031163)3.31045291
107iron-sulfur cluster assembly (GO:0016226)3.31045291
108mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.30532671
109macromolecular complex disassembly (GO:0032984)3.29465955
110GTP biosynthetic process (GO:0006183)3.28879121
111nuclear-transcribed mRNA catabolic process (GO:0000956)3.27580833
112cytochrome complex assembly (GO:0017004)3.26081572
113UTP biosynthetic process (GO:0006228)3.26054579
114ncRNA processing (GO:0034470)3.25300471
115positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.24765618
116oxidative phosphorylation (GO:0006119)3.22806348
117exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.21323225
118chromatin remodeling at centromere (GO:0031055)3.19669684
119ncRNA metabolic process (GO:0034660)3.19011293
120deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.17951891
121RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.16279232
122tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.16279232
123deoxyribonucleotide catabolic process (GO:0009264)3.13558768
124deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.12772545
125ATP biosynthetic process (GO:0006754)3.12324229
126establishment of protein localization to mitochondrion (GO:0072655)3.12210298
127mitochondrial transport (GO:0006839)3.12124637
128purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.11384297
129regulation of spindle organization (GO:0090224)3.11366293
130CENP-A containing nucleosome assembly (GO:0034080)3.11050927
131pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.10876173
132purine nucleoside triphosphate biosynthetic process (GO:0009145)3.09732327
133positive regulation of ligase activity (GO:0051351)3.09687607
134nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.08713795
135mRNA catabolic process (GO:0006402)3.08500757
136protein targeting to mitochondrion (GO:0006626)3.07285491
137inner mitochondrial membrane organization (GO:0007007)3.06575502

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.88192440
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.85267839
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.50559745
4GABP_17652178_ChIP-ChIP_JURKAT_Human4.03658585
5* JARID1A_20064375_ChIP-Seq_MESCs_Mouse4.00716989
6ETS1_20019798_ChIP-Seq_JURKAT_Human3.84919817
7* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.76219851
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.73429734
9TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.60364725
10MYC_19079543_ChIP-ChIP_MESCs_Mouse3.35068519
11CREB1_15753290_ChIP-ChIP_HEK293T_Human3.30759222
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.26873206
13* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.24591652
14* MYC_19030024_ChIP-ChIP_MESCs_Mouse3.10229317
15NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.96880239
16SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.96713085
17E2F4_17652178_ChIP-ChIP_JURKAT_Human2.88331682
18VDR_23849224_ChIP-Seq_CD4+_Human2.81796844
19E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.75661123
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.73703465
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.60548474
22XRN2_22483619_ChIP-Seq_HELA_Human2.55608303
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.48192171
24FOXP3_21729870_ChIP-Seq_TREG_Human2.43473915
25DCP1A_22483619_ChIP-Seq_HELA_Human2.43067137
26THAP11_20581084_ChIP-Seq_MESCs_Mouse2.38109413
27FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.30978832
28E2F1_18555785_ChIP-Seq_MESCs_Mouse2.28900073
29GABP_19822575_ChIP-Seq_HepG2_Human2.25079046
30TTF2_22483619_ChIP-Seq_HELA_Human2.19789540
31ELF1_17652178_ChIP-ChIP_JURKAT_Human2.16929450
32NELFA_20434984_ChIP-Seq_ESCs_Mouse2.16742152
33YY1_21170310_ChIP-Seq_MESCs_Mouse2.14304567
34FOXM1_23109430_ChIP-Seq_U2OS_Human2.12409205
35* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.92703427
36FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.92198807
37* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.88980236
38NANOG_18555785_ChIP-Seq_MESCs_Mouse1.88906540
39SRF_21415370_ChIP-Seq_HL-1_Mouse1.87228324
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.81546306
41MYCN_18555785_ChIP-Seq_MESCs_Mouse1.79882549
42PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.77062407
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.77010423
44MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.76050820
45ELK1_19687146_ChIP-ChIP_HELA_Human1.75359139
46PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.69925348
47* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.68011121
48* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.66822564
49MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.65991663
50CIITA_25753668_ChIP-Seq_RAJI_Human1.64296522
51NOTCH1_21737748_ChIP-Seq_TLL_Human1.62150892
52HOXB4_20404135_ChIP-ChIP_EML_Mouse1.61061233
53MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.59616374
54ZFX_18555785_ChIP-Seq_MESCs_Mouse1.50917113
55ELK1_22589737_ChIP-Seq_MCF10A_Human1.48927378
56ERG_20887958_ChIP-Seq_HPC-7_Mouse1.48319205
57* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.44037334
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.43273789
59NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.37194818
60KDM5A_27292631_Chip-Seq_BREAST_Human1.36322990
61POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.34334711
62AR_21909140_ChIP-Seq_LNCAP_Human1.33455474
63CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.30849746
64ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.25857807
65PADI4_21655091_ChIP-ChIP_MCF-7_Human1.22605591
66MYC_18940864_ChIP-ChIP_HL60_Human1.22172644
67CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.20975517
68BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.19673226
69KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.13696704
70SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.12957304
71GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.12327232
72KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.11787131
73TET1_21451524_ChIP-Seq_MESCs_Mouse1.11109754
74* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.09347137
75ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.08615878
76IRF1_19129219_ChIP-ChIP_H3396_Human1.07746087
77DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.06160883
78TFEB_21752829_ChIP-Seq_HELA_Human1.05665176
79SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.02941931
80CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.00616556
81KLF4_18555785_ChIP-Seq_MESCs_Mouse0.99042868
82SRY_22984422_ChIP-ChIP_TESTIS_Rat0.98312393
83E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.98145094
84DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.95220394
85SOX2_18555785_ChIP-Seq_MESCs_Mouse0.94400564
86SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.92983691
87ZNF263_19887448_ChIP-Seq_K562_Human0.92786064
88TP63_19390658_ChIP-ChIP_HaCaT_Human0.91797778
89HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.89282576
90TBX5_21415370_ChIP-Seq_HL-1_Mouse0.88128477
91CTCF_18555785_ChIP-Seq_MESCs_Mouse0.87954805
92FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86904567
93MYC_22102868_ChIP-Seq_BL_Human0.85220248
94PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.84803863
95CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.84733657
96* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.84704658
97* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.83135751
98P68_20966046_ChIP-Seq_HELA_Human0.82685771
99ELF1_20517297_ChIP-Seq_JURKAT_Human0.82173102
100YY1_22570637_ChIP-Seq_MALME-3M_Human0.81992360
101CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.80691001
102CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.80399257
103STAT3_1855785_ChIP-Seq_MESCs_Mouse0.80123715
104SPI1_23547873_ChIP-Seq_NB4_Human0.79713270
105GATA1_22025678_ChIP-Seq_K562_Human0.79671697
106CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.79599933
107SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.79271367
108CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.79247107
109ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.78577957
110OCT4_18692474_ChIP-Seq_MEFs_Mouse0.77944288
111FOXP1_21924763_ChIP-Seq_HESCs_Human0.77042592
112CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.76326808
113EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.75324068
114POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.71635594
115HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.70560149

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.61983159
2MP0004957_abnormal_blastocyst_morpholog4.81859635
3MP0003111_abnormal_nucleus_morphology4.48725100
4MP0008058_abnormal_DNA_repair3.81108623
5MP0003077_abnormal_cell_cycle3.73441212
6MP0010094_abnormal_chromosome_stability3.41567048
7MP0008932_abnormal_embryonic_tissue3.25896270
8MP0008057_abnormal_DNA_replication3.05146604
9MP0009379_abnormal_foot_pigmentation2.70917911
10MP0008260_abnormal_autophagy2.64658111
11MP0002396_abnormal_hematopoietic_system2.56599491
12MP0006292_abnormal_olfactory_placode2.45219101
13MP0008007_abnormal_cellular_replicative2.45138440
14MP0003786_premature_aging2.20202028
15MP0003787_abnormal_imprinting2.11827307
16MP0003941_abnormal_skin_development2.11824389
17MP0002163_abnormal_gland_morphology2.00601494
18MP0003123_paternal_imprinting1.99189301
19MP0006036_abnormal_mitochondrial_physio1.92876955
20MP0006035_abnormal_mitochondrial_morpho1.87373387
21MP0001730_embryonic_growth_arrest1.83254000
22MP0004145_abnormal_muscle_electrophysio1.78654169
23MP0008877_abnormal_DNA_methylation1.76849496
24MP0009333_abnormal_splenocyte_physiolog1.71021752
25MP0000350_abnormal_cell_proliferation1.65563954
26MP0003718_maternal_effect1.64890138
27MP0000490_abnormal_crypts_of1.60660210
28MP0001986_abnormal_taste_sensitivity1.60363587
29MP0010030_abnormal_orbit_morphology1.52834542
30MP0001919_abnormal_reproductive_system1.47023935
31MP0008789_abnormal_olfactory_epithelium1.45925450
32MP0003879_abnormal_hair_cell1.42752682
33MP0000372_irregular_coat_pigmentation1.42544533
34MP0006072_abnormal_retinal_apoptosis1.42501262
35MP0001188_hyperpigmentation1.39660825
36MP0002132_abnormal_respiratory_system1.39643471
37MP0000313_abnormal_cell_death1.37835212
38MP0003011_delayed_dark_adaptation1.34857664
39MP0002080_prenatal_lethality1.34837181
40MP0003763_abnormal_thymus_physiology1.34127512
41MP0005379_endocrine/exocrine_gland_phen1.34059486
42MP0000358_abnormal_cell_content/1.33464094
43MP0003315_abnormal_perineum_morphology1.33167342
44MP0001727_abnormal_embryo_implantation1.32809083
45MP0001697_abnormal_embryo_size1.27702175
46MP0002736_abnormal_nociception_after1.27379062
47MP0002653_abnormal_ependyma_morphology1.26831281
48MP0002638_abnormal_pupillary_reflex1.25462513
49MP0002938_white_spotting1.24774230
50MP0000703_abnormal_thymus_morphology1.21732949
51MP0001293_anophthalmia1.19628648
52MP0002837_dystrophic_cardiac_calcinosis1.16291991
53MP0005380_embryogenesis_phenotype1.15220844
54MP0001672_abnormal_embryogenesis/_devel1.15220844
55MP0002102_abnormal_ear_morphology1.13496123
56MP0002277_abnormal_respiratory_mucosa1.11138898
57MP0001529_abnormal_vocalization1.11025386
58MP0005220_abnormal_exocrine_pancreas1.10350180
59MP0005174_abnormal_tail_pigmentation1.10237930
60MP0003567_abnormal_fetal_cardiomyocyte1.09107542
61MP0004808_abnormal_hematopoietic_stem1.08709685
62MP0002398_abnormal_bone_marrow1.08385977
63MP0005394_taste/olfaction_phenotype1.07499083
64MP0005499_abnormal_olfactory_system1.07499083
65MP0002085_abnormal_embryonic_tissue1.07433192
66MP0005501_abnormal_skin_physiology1.07317500
67MP0002210_abnormal_sex_determination1.06863667
68MP0002019_abnormal_tumor_incidence1.06583927
69MP0004133_heterotaxia1.06407087
70MP0005423_abnormal_somatic_nervous1.06269828
71MP0003698_abnormal_male_reproductive1.05522007
72MP0002095_abnormal_skin_pigmentation1.04779173
73MP0003221_abnormal_cardiomyocyte_apopto1.03330963
74MP0001984_abnormal_olfaction1.02311744
75MP0002722_abnormal_immune_system1.01973776
76MP0003890_abnormal_embryonic-extraembry0.99949736
77MP0005075_abnormal_melanosome_morpholog0.98607005
78MP0003984_embryonic_growth_retardation0.97859603
79MP0000689_abnormal_spleen_morphology0.96937222
80MP0002088_abnormal_embryonic_growth/wei0.95942915
81MP0003646_muscle_fatigue0.95464156
82MP0000678_abnormal_parathyroid_gland0.94042638
83MP0005397_hematopoietic_system_phenotyp0.92764229
84MP0001545_abnormal_hematopoietic_system0.92764229
85MP0001145_abnormal_male_reproductive0.91819166
86MP0003119_abnormal_digestive_system0.90752703
87MP0005451_abnormal_body_composition0.90095598
88MP0005384_cellular_phenotype0.88515760
89MP0000750_abnormal_muscle_regeneration0.86661504
90MP0000647_abnormal_sebaceous_gland0.85907879
91MP0003121_genomic_imprinting0.84830192
92MP0002796_impaired_skin_barrier0.84629297
93MP0001929_abnormal_gametogenesis0.82326243
94MP0002234_abnormal_pharynx_morphology0.82117507
95MP0005410_abnormal_fertilization0.81731371
96MP0002429_abnormal_blood_cell0.81077637
97MP0002161_abnormal_fertility/fecundity0.80597812
98MP0005671_abnormal_response_to0.80538237
99MP0003186_abnormal_redox_activity0.79924560
100MP0002160_abnormal_reproductive_system0.79679580
101MP0005670_abnormal_white_adipose0.78811908
102MP0006276_abnormal_autonomic_nervous0.78185035
103MP0001968_abnormal_touch/_nociception0.77129794
104MP0000579_abnormal_nail_morphology0.77092280
105MP0003937_abnormal_limbs/digits/tail_de0.76444436
106MP0008995_early_reproductive_senescence0.76175681
107MP0009046_muscle_twitch0.74712642
108MP0000716_abnormal_immune_system0.73098976
109MP0002249_abnormal_larynx_morphology0.73088328
110MP0001764_abnormal_homeostasis0.72983712
111MP0000631_abnormal_neuroendocrine_gland0.72286178
112MP0001485_abnormal_pinna_reflex0.71836372
113MP0004215_abnormal_myocardial_fiber0.71166706
114MP0005409_darkened_coat_color0.70859279
115MP0000653_abnormal_sex_gland0.70746177
116MP0004142_abnormal_muscle_tone0.70274891
117MP0003806_abnormal_nucleotide_metabolis0.68779571
118MP0005253_abnormal_eye_physiology0.68677547
119MP0000049_abnormal_middle_ear0.68672193
120MP0002090_abnormal_vision0.68656956
121MP0005621_abnormal_cell_physiology0.67763868
122MP0002254_reproductive_system_inflammat0.67595871
123MP0001873_stomach_inflammation0.67190377
124MP0002751_abnormal_autonomic_nervous0.66669244
125MP0003878_abnormal_ear_physiology0.66546808
126MP0005377_hearing/vestibular/ear_phenot0.66546808
127MP0001119_abnormal_female_reproductive0.66543951
128MP0009697_abnormal_copulation0.65988562
129MP0000516_abnormal_urinary_system0.65748004
130MP0005367_renal/urinary_system_phenotyp0.65748004
131MP0003938_abnormal_ear_development0.64527224
132MP0002084_abnormal_developmental_patter0.63719464
133MP0001346_abnormal_lacrimal_gland0.63423425
134MP0003122_maternal_imprinting0.63372762
135MP0002086_abnormal_extraembryonic_tissu0.60653801
136MP0001905_abnormal_dopamine_level0.59935033
137MP0005389_reproductive_system_phenotype0.59188152
138MP0002269_muscular_atrophy0.58394025
139MP0003136_yellow_coat_color0.58149782
140MP0000015_abnormal_ear_pigmentation0.57879818
141MP0004084_abnormal_cardiac_muscle0.57411757
142MP0005084_abnormal_gallbladder_morpholo0.57266340
143MP0005636_abnormal_mineral_homeostasis0.55333091
144MP0001800_abnormal_humoral_immune0.54424789
145MP0005395_other_phenotype0.53962093
146MP0004197_abnormal_fetal_growth/weight/0.53913648

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.08587467
2Reticulocytopenia (HP:0001896)5.06183254
3Abnormal number of erythroid precursors (HP:0012131)5.04898771
4Acute necrotizing encephalopathy (HP:0006965)4.47128937
5Birth length less than 3rd percentile (HP:0003561)4.40317652
6Cerebral hypomyelination (HP:0006808)4.22150657
7Abnormal mitochondria in muscle tissue (HP:0008316)3.95112321
8Mitochondrial inheritance (HP:0001427)3.94324242
9Progressive muscle weakness (HP:0003323)3.88848158
10Macrocytic anemia (HP:0001972)3.88250093
11Breast hypoplasia (HP:0003187)3.82833335
12Increased CSF lactate (HP:0002490)3.68664909
13Microvesicular hepatic steatosis (HP:0001414)3.66546213
14Pallor (HP:0000980)3.59047882
15Hepatocellular necrosis (HP:0001404)3.57890799
16Progressive macrocephaly (HP:0004481)3.49231104
17Renal Fanconi syndrome (HP:0001994)3.48218330
18Increased intramyocellular lipid droplets (HP:0012240)3.42071087
19Rough bone trabeculation (HP:0100670)3.30401396
20Increased serum pyruvate (HP:0003542)3.28378795
21Abnormality of glycolysis (HP:0004366)3.28378795
22Acute encephalopathy (HP:0006846)3.27908103
23Oral leukoplakia (HP:0002745)3.22349777
243-Methylglutaconic aciduria (HP:0003535)3.20279109
25Aplastic anemia (HP:0001915)3.16051852
26Increased serum lactate (HP:0002151)3.13906669
27Hepatic necrosis (HP:0002605)3.05799986
28Increased muscle lipid content (HP:0009058)2.95505578
29Type I transferrin isoform profile (HP:0003642)2.85723424
30Abnormality of the preputium (HP:0100587)2.82716605
31Premature graying of hair (HP:0002216)2.80567505
32Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.78990471
33Decreased activity of mitochondrial respiratory chain (HP:0008972)2.78990471
34Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.75916495
35Secondary amenorrhea (HP:0000869)2.74472919
36Testicular atrophy (HP:0000029)2.73244661
37Trismus (HP:0000211)2.72633916
38Abnormality of the anterior horn cell (HP:0006802)2.63773563
39Degeneration of anterior horn cells (HP:0002398)2.63773563
40Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.63434097
41Lactic acidosis (HP:0003128)2.63254399
42Ragged-red muscle fibers (HP:0003200)2.63049635
43IgM deficiency (HP:0002850)2.59023900
44Pancytopenia (HP:0001876)2.57993004
45Exercise intolerance (HP:0003546)2.54921325
46Absent thumb (HP:0009777)2.53752359
47Cerebral edema (HP:0002181)2.51076954
48Multiple enchondromatosis (HP:0005701)2.49589611
49Patellar aplasia (HP:0006443)2.48178731
50Lethargy (HP:0001254)2.43082465
51Meckel diverticulum (HP:0002245)2.42625767
52CNS hypomyelination (HP:0003429)2.41680791
53Microretrognathia (HP:0000308)2.41213804
54Respiratory difficulties (HP:0002880)2.39165054
55Carpal bone hypoplasia (HP:0001498)2.39135840
56Reduced antithrombin III activity (HP:0001976)2.38436302
57Hyperglycinemia (HP:0002154)2.38161203
58Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.36317059
59Abnormality of alanine metabolism (HP:0010916)2.36317059
60Hyperalaninemia (HP:0003348)2.36317059
61Abnormality of the heme biosynthetic pathway (HP:0010472)2.34074969
62Aplasia/Hypoplasia of the patella (HP:0006498)2.34061123
63Increased hepatocellular lipid droplets (HP:0006565)2.32533462
64CNS demyelination (HP:0007305)2.31440662
65Abnormal trabecular bone morphology (HP:0100671)2.30563471
66Respiratory failure (HP:0002878)2.30085662
67Aplasia/Hypoplasia of the sacrum (HP:0008517)2.28195118
68Emotional lability (HP:0000712)2.27128804
69Horseshoe kidney (HP:0000085)2.25762394
70Aplasia/hypoplasia of the uterus (HP:0008684)2.23813358
71Abnormality of the ileum (HP:0001549)2.23699039
72Premature ovarian failure (HP:0008209)2.22632278
73Abnormality of chromosome stability (HP:0003220)2.22043296
74Triphalangeal thumb (HP:0001199)2.22036317
75Exertional dyspnea (HP:0002875)2.22003773
76Cellular immunodeficiency (HP:0005374)2.20697246
77Cleft eyelid (HP:0000625)2.20391196
78Neoplasm of the pancreas (HP:0002894)2.15400049
79Bone marrow hypocellularity (HP:0005528)2.13344121
80Optic disc pallor (HP:0000543)2.11667142
81Hyperphosphaturia (HP:0003109)2.08822453
82Poor suck (HP:0002033)2.08675620
83Chromsome breakage (HP:0040012)2.07176943
84Aplasia/Hypoplasia of the uvula (HP:0010293)2.05147236
85Stomach cancer (HP:0012126)2.05012419
86Abnormality of the labia minora (HP:0012880)2.04863452
87Hypoplasia of the pons (HP:0012110)2.04618611
88Myelodysplasia (HP:0002863)2.01650866
89Unsteady gait (HP:0002317)2.01591876
90Abnormality of renal resorption (HP:0011038)1.98760301
91Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.98716997
92Abnormal protein N-linked glycosylation (HP:0012347)1.98716997
93Abnormal protein glycosylation (HP:0012346)1.98716997
94Abnormal glycosylation (HP:0012345)1.98716997
95Progressive external ophthalmoplegia (HP:0000590)1.98707540
96Lymphoma (HP:0002665)1.98279271
97Hypoplasia of the radius (HP:0002984)1.97869999
98Depressed nasal ridge (HP:0000457)1.95997282
99Myokymia (HP:0002411)1.95881242
100X-linked dominant inheritance (HP:0001423)1.94829254
101Impulsivity (HP:0100710)1.94267100
102Abnormality of the pons (HP:0007361)1.93691559
103Abnormality of urine glucose concentration (HP:0011016)1.93100449
104Glycosuria (HP:0003076)1.93100449
105Methylmalonic aciduria (HP:0012120)1.91904953
106Abnormality of midbrain morphology (HP:0002418)1.91855423
107Molar tooth sign on MRI (HP:0002419)1.91855423
108Abnormal number of incisors (HP:0011064)1.91466176
109Hypoplasia of the uterus (HP:0000013)1.89867920
110Lipid accumulation in hepatocytes (HP:0006561)1.89843019
111IgG deficiency (HP:0004315)1.88780412
112Colon cancer (HP:0003003)1.88168783
113Progressive microcephaly (HP:0000253)1.86090345
114Postnatal microcephaly (HP:0005484)1.85715153
115Tongue fasciculations (HP:0001308)1.83539030
116Delusions (HP:0000746)1.83231379
117Sparse eyelashes (HP:0000653)1.82840901
118Abnormality of reticulocytes (HP:0004312)1.82766690
119Adrenal hypoplasia (HP:0000835)1.82698516
120Leukodystrophy (HP:0002415)1.82511407
121Atrophy/Degeneration involving motor neurons (HP:0007373)1.81580505
122Blindness (HP:0000618)1.81446491
123Congenital, generalized hypertrichosis (HP:0004540)1.81432503
124Long foot (HP:0001833)1.80385566
125Generalized aminoaciduria (HP:0002909)1.78917544
126Absent radius (HP:0003974)1.77391107
127Entropion (HP:0000621)1.77186934
128Sensory axonal neuropathy (HP:0003390)1.74212591
129Facial cleft (HP:0002006)1.73114335
130Sclerocornea (HP:0000647)1.70991128
131Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.69581590
132Abnormality of serum amino acid levels (HP:0003112)1.68507988
133Retinal dysplasia (HP:0007973)1.68239838
134Hypoglycemic coma (HP:0001325)1.65259157
135Death in infancy (HP:0001522)1.64416392
136Hyperinsulinemic hypoglycemia (HP:0000825)1.64278296
137Gliosis (HP:0002171)1.63040641
138Abnormality of magnesium homeostasis (HP:0004921)1.60013381
139Abnormality of dicarboxylic acid metabolism (HP:0010995)1.59938268
140Dicarboxylic aciduria (HP:0003215)1.59938268
141Prominent metopic ridge (HP:0005487)1.59796015
142Abnormal urine phosphate concentration (HP:0012599)1.58516240

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.29759940
2STK164.98805141
3BUB13.97263355
4ZAK3.82326419
5NME23.56706659
6EIF2AK13.45562112
7WEE13.44056805
8TSSK62.95553375
9EIF2AK32.90842752
10NME12.82129206
11PBK2.79742542
12TTK2.52658642
13SRPK12.49871868
14CAMKK22.40197140
15TRIM282.19404392
16TLK12.14817646
17ACVR1B2.12220638
18VRK12.05576645
19TESK11.99334202
20PNCK1.92458885
21BCKDK1.74968209
22PIM21.72504124
23DYRK31.71278320
24TESK21.67042430
25CDC71.64198979
26PDK21.62970921
27PLK31.61132265
28PLK11.47129224
29PLK41.44172113
30TAF11.42298479
31NUAK11.41664340
32MKNK11.39864736
33BRAF1.39159328
34MKNK21.32928506
35CSNK1G31.31780692
36IRAK31.25048703
37LIMK11.23840001
38ATR1.22972701
39AURKB1.21287812
40PASK1.20211218
41NEK21.13346403
42CDK71.12976316
43CHEK21.11604083
44ABL21.10057577
45ADRBK21.09260892
46CSNK1G11.07504464
47TXK1.07003297
48MAP4K11.06843247
49MAP3K111.02690493
50PRKCI1.00714598
51CSNK1G20.99835238
52BRSK20.96950464
53MAP2K70.92186260
54CDK190.91244082
55SMG10.90101793
56AURKA0.89799062
57CSNK1A1L0.89769145
58TNIK0.87329765
59MATK0.83394116
60EIF2AK20.81279987
61CCNB10.77794420
62CHEK10.77324376
63IRAK40.75505514
64NEK10.75367840
65ZAP700.75083445
66KDR0.72377618
67MAP3K80.71673660
68TAOK20.71290949
69ILK0.71227889
70MINK10.69427104
71DYRK20.68554918
72CSNK2A20.68249418
73ARAF0.68055330
74CASK0.66151823
75BRSK10.65850036
76CSNK2A10.65567898
77RPS6KA40.63470751
78STK40.62952442
79WNK40.62604505
80STK240.62171595
81PRKCG0.61331440
82SIK30.60878857
83CAMK1D0.55707007
84AKT30.54876502
85CAMK10.54858634
86MAPKAPK50.54330624
87EPHA20.54094561
88TAOK10.53723428
89RPS6KB20.53198815
90PAK40.52640765
91WNK30.51557964
92RPS6KA50.49275312
93ATM0.48189734
94CDK20.47280157
95OXSR10.46583316
96PIM10.45357388
97MUSK0.42863930
98MST40.42035924
99CDK30.41607318
100CDK11A0.41521271
101PAK10.41162664
102BMPR1B0.39687277
103MAP4K20.39662817
104GRK10.38922773
105TEC0.38414146
106CDK140.37603330
107CDK80.37270549
108CDK10.36595807
109CSNK1A10.36014727
110CSNK1E0.34386644
111STK100.33899519
112GRK70.32872398
113LYN0.30432062
114CDK180.29561747
115TGFBR10.28704924
116CDK150.28137544
117AKT20.27729466
118CLK10.27506932
119CDK40.27317082
120PDK30.27146573
121PDK40.27146573
122SCYL20.26546555
123ALK0.25286270
124ADRBK10.23962095
125PRKDC0.22500109
126MARK30.21094389
127IRAK20.20899971
128MAPKAPK30.19424584
129LRRK20.19257262
130LCK0.19168363
131OBSCN0.18329842
132DAPK10.17775113
133CAMK1G0.17346822
134DAPK30.16842088
135NLK0.16497420

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.80336488
2Proteasome_Homo sapiens_hsa030504.27970687
3RNA polymerase_Homo sapiens_hsa030204.20105223
4DNA replication_Homo sapiens_hsa030304.14977418
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.74531633
6Mismatch repair_Homo sapiens_hsa034303.66895640
7Spliceosome_Homo sapiens_hsa030403.09318372
8Nucleotide excision repair_Homo sapiens_hsa034202.94344929
9Homologous recombination_Homo sapiens_hsa034402.74424667
10RNA transport_Homo sapiens_hsa030132.72935782
11Pyrimidine metabolism_Homo sapiens_hsa002402.71755682
12Vitamin B6 metabolism_Homo sapiens_hsa007502.54602348
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.25272678
14Oxidative phosphorylation_Homo sapiens_hsa001902.14064680
15Protein export_Homo sapiens_hsa030602.11859109
16Basal transcription factors_Homo sapiens_hsa030222.01986394
17Parkinsons disease_Homo sapiens_hsa050122.00653972
18Base excision repair_Homo sapiens_hsa034101.92970837
19One carbon pool by folate_Homo sapiens_hsa006701.91504955
20Cell cycle_Homo sapiens_hsa041101.84772701
21Fanconi anemia pathway_Homo sapiens_hsa034601.79765889
22Huntingtons disease_Homo sapiens_hsa050161.76619516
23RNA degradation_Homo sapiens_hsa030181.72161276
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.58326264
25Purine metabolism_Homo sapiens_hsa002301.56714207
26Non-homologous end-joining_Homo sapiens_hsa034501.47204493
27p53 signaling pathway_Homo sapiens_hsa041151.34380572
28Sulfur relay system_Homo sapiens_hsa041221.28939004
29Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.28857066
30Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.27645508
31Folate biosynthesis_Homo sapiens_hsa007901.27122493
32mRNA surveillance pathway_Homo sapiens_hsa030151.22974990
33Alzheimers disease_Homo sapiens_hsa050101.15870200
34Epstein-Barr virus infection_Homo sapiens_hsa051691.06932729
35Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.05963393
36Regulation of autophagy_Homo sapiens_hsa041401.04660160
37Sulfur metabolism_Homo sapiens_hsa009201.02870067
38Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.00548600
39Pentose phosphate pathway_Homo sapiens_hsa000300.90013734
40Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.83823762
41Cysteine and methionine metabolism_Homo sapiens_hsa002700.83392564
42Cyanoamino acid metabolism_Homo sapiens_hsa004600.80367605
43Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.78772781
44Peroxisome_Homo sapiens_hsa041460.77755667
45Steroid biosynthesis_Homo sapiens_hsa001000.77740914
46Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.77454324
47Primary immunodeficiency_Homo sapiens_hsa053400.74166505
48Cardiac muscle contraction_Homo sapiens_hsa042600.69489321
49Antigen processing and presentation_Homo sapiens_hsa046120.67404785
50Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.65518472
51Fatty acid elongation_Homo sapiens_hsa000620.63706417
52Propanoate metabolism_Homo sapiens_hsa006400.61573402
53Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.59501395
54Metabolic pathways_Homo sapiens_hsa011000.57350941
55Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.57012907
56Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.52914156
57Drug metabolism - other enzymes_Homo sapiens_hsa009830.49832457
58Systemic lupus erythematosus_Homo sapiens_hsa053220.48419238
59Oocyte meiosis_Homo sapiens_hsa041140.48247890
60Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.47856920
61Biosynthesis of amino acids_Homo sapiens_hsa012300.46643574
62Synaptic vesicle cycle_Homo sapiens_hsa047210.44821684
63Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.44076233
64Carbon metabolism_Homo sapiens_hsa012000.43263933
65Herpes simplex infection_Homo sapiens_hsa051680.41985282
66Maturity onset diabetes of the young_Homo sapiens_hsa049500.41383472
67Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.40374797
68Glutathione metabolism_Homo sapiens_hsa004800.40312077
69Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.36363397
70Pentose and glucuronate interconversions_Homo sapiens_hsa000400.35781435
71Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.34341178
72Viral carcinogenesis_Homo sapiens_hsa052030.32933431
73Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.30429384
74Fructose and mannose metabolism_Homo sapiens_hsa000510.29927148
75Phototransduction_Homo sapiens_hsa047440.29302766
76N-Glycan biosynthesis_Homo sapiens_hsa005100.29063366
77Selenocompound metabolism_Homo sapiens_hsa004500.28653031
78Butanoate metabolism_Homo sapiens_hsa006500.28268058
79Intestinal immune network for IgA production_Homo sapiens_hsa046720.28076890
80Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.27372334
81Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.27031873
82HTLV-I infection_Homo sapiens_hsa051660.26260589
83Hematopoietic cell lineage_Homo sapiens_hsa046400.25286960
84Fatty acid metabolism_Homo sapiens_hsa012120.24246000
85Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.24212208
86SNARE interactions in vesicular transport_Homo sapiens_hsa041300.22491719
87Vitamin digestion and absorption_Homo sapiens_hsa049770.21858829
88Thyroid cancer_Homo sapiens_hsa052160.21697762
89Arginine biosynthesis_Homo sapiens_hsa002200.20180475
90beta-Alanine metabolism_Homo sapiens_hsa004100.16828921
91Tryptophan metabolism_Homo sapiens_hsa003800.16375875
92Arachidonic acid metabolism_Homo sapiens_hsa005900.15004669
93Glycerophospholipid metabolism_Homo sapiens_hsa005640.13912163
94Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.13722658
95Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.12930162
96Apoptosis_Homo sapiens_hsa042100.12139138
97Sphingolipid metabolism_Homo sapiens_hsa006000.11940995
98Circadian rhythm_Homo sapiens_hsa047100.11488827
99Primary bile acid biosynthesis_Homo sapiens_hsa001200.11027010
100Fatty acid degradation_Homo sapiens_hsa000710.11001207
1012-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.10976052
102Chemical carcinogenesis_Homo sapiens_hsa052040.10940827
103Alcoholism_Homo sapiens_hsa050340.10813169
104Arginine and proline metabolism_Homo sapiens_hsa003300.10636876
105Collecting duct acid secretion_Homo sapiens_hsa049660.10403511
106Fat digestion and absorption_Homo sapiens_hsa049750.09641628
107Shigellosis_Homo sapiens_hsa051310.09380893
108Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.07024632
109Linoleic acid metabolism_Homo sapiens_hsa005910.06973736
110Tyrosine metabolism_Homo sapiens_hsa003500.06334578
111NF-kappa B signaling pathway_Homo sapiens_hsa040640.04452137
112Phenylalanine metabolism_Homo sapiens_hsa003600.03876938
113RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.03770751
114Legionellosis_Homo sapiens_hsa051340.03027135
115Other glycan degradation_Homo sapiens_hsa005110.02132158
116Vibrio cholerae infection_Homo sapiens_hsa051100.01770469
117Renin-angiotensin system_Homo sapiens_hsa046140.01726375
118Pyruvate metabolism_Homo sapiens_hsa006200.01552134
119NOD-like receptor signaling pathway_Homo sapiens_hsa046210.00839286
120Measles_Homo sapiens_hsa051620.00330765
121Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010-0.0401019
122Galactose metabolism_Homo sapiens_hsa00052-0.0361500
123Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080-0.0096177
124Acute myeloid leukemia_Homo sapiens_hsa05221-0.0010941

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