SUSD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of B cell differentiation (GO:0045579)4.99268975
2positive regulation of gamma-delta T cell activation (GO:0046645)4.98211765
3antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.87467176
4antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.87467176
5ribosomal small subunit assembly (GO:0000028)4.63260480
6antigen processing and presentation of endogenous antigen (GO:0019883)4.57659816
7positive regulation of mast cell activation (GO:0033005)4.52217535
8positive regulation by symbiont of host defense response (GO:0052509)4.50263249
9modulation by symbiont of host defense response (GO:0052031)4.50263249
10modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.50263249
11modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.50263249
12positive regulation by organism of defense response of other organism involved in symbiotic interact4.50263249
13modulation by symbiont of host immune response (GO:0052553)4.50263249
14B cell receptor signaling pathway (GO:0050853)4.33683395
15cellular extravasation (GO:0045123)4.31241379
16negative regulation of phagocytosis (GO:0050765)4.29178841
17definitive hemopoiesis (GO:0060216)4.14884568
18positive regulation of mast cell degranulation (GO:0043306)3.89447565
19positive regulation of mast cell activation involved in immune response (GO:0033008)3.89447565
20regulation of mast cell activation involved in immune response (GO:0033006)3.87026730
21regulation of B cell differentiation (GO:0045577)3.84821088
22granulocyte activation (GO:0036230)3.83807775
23negative regulation of interleukin-12 production (GO:0032695)3.83677444
24macrophage activation involved in immune response (GO:0002281)3.82899463
25microglial cell activation (GO:0001774)3.77323232
26regulation of mast cell activation (GO:0033003)3.76926388
27negative regulation of cell killing (GO:0031342)3.70635805
28negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.70635805
29DNA unwinding involved in DNA replication (GO:0006268)3.61452970
30detection of molecule of bacterial origin (GO:0032490)3.60395211
31regulation of myeloid leukocyte mediated immunity (GO:0002886)3.59815626
32regulation of gamma-delta T cell differentiation (GO:0045586)3.57082399
33regulation of leukocyte degranulation (GO:0043300)3.55538225
34positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.54570094
35telomere maintenance via semi-conservative replication (GO:0032201)3.53220505
36regulation of platelet aggregation (GO:0090330)3.50031038
37leukocyte migration involved in inflammatory response (GO:0002523)3.47059091
38positive regulation of cellular amide metabolic process (GO:0034250)3.44981447
39regulation of gamma-delta T cell activation (GO:0046643)3.42401395
40regulation of histone H3-K9 methylation (GO:0051570)3.41126527
41thrombin receptor signaling pathway (GO:0070493)3.38252181
42T cell homeostasis (GO:0043029)3.37967944
43positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.36372814
44cellular response to thyroid hormone stimulus (GO:0097067)3.35919343
45macrophage activation (GO:0042116)3.35546743
46antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.34330808
47myeloid cell activation involved in immune response (GO:0002275)3.32042689
48detection of other organism (GO:0098543)3.31954586
49DNA strand elongation involved in DNA replication (GO:0006271)3.30169872
50regulation of platelet activation (GO:0010543)3.29400065
51positive regulation of leukocyte degranulation (GO:0043302)3.27461562
52response to host immune response (GO:0052572)3.27397565
53response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.27397565
54megakaryocyte development (GO:0035855)3.26077884
55regulation of B cell receptor signaling pathway (GO:0050855)3.23962767
56antigen processing and presentation via MHC class Ib (GO:0002475)3.22904840
57lipopolysaccharide-mediated signaling pathway (GO:0031663)3.21558400
58DNA strand elongation (GO:0022616)3.20360253
59DNA topological change (GO:0006265)3.16961294
60Arp2/3 complex-mediated actin nucleation (GO:0034314)3.13932756
61detection of external biotic stimulus (GO:0098581)3.11580234
62response to host (GO:0075136)3.11082884
63response to host defenses (GO:0052200)3.11082884
64response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.11082884
65positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.09873560
66protein localization to kinetochore (GO:0034501)3.09780221
67telomere maintenance via recombination (GO:0000722)3.09692675
68response to muramyl dipeptide (GO:0032495)3.05954634
69regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.04754834
70mitotic recombination (GO:0006312)3.01971360
71V(D)J recombination (GO:0033151)3.00728941
72deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.98488113
73lymphocyte homeostasis (GO:0002260)2.97865294
74detection of bacterium (GO:0016045)2.96717470
75regulation of T-helper 2 cell differentiation (GO:0045628)2.96257030
76regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.91797833
77positive regulation of granulocyte differentiation (GO:0030854)2.88860659
78cellular hyperosmotic response (GO:0071474)2.88804804
79hepatocyte apoptotic process (GO:0097284)2.88702902
80viral transcription (GO:0019083)2.87128995
81oligosaccharide catabolic process (GO:0009313)2.85556436
82detection of biotic stimulus (GO:0009595)2.81050491
83response to thyroid hormone (GO:0097066)2.79801814
84regulation of regulated secretory pathway (GO:1903305)2.79539557
85neutrophil activation involved in immune response (GO:0002283)2.79110747
86positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.77848826
87immunoglobulin mediated immune response (GO:0016064)2.77546730
88positive regulation of type 2 immune response (GO:0002830)2.77413302
89response to peptidoglycan (GO:0032494)2.75275777
90protein localization to chromosome, centromeric region (GO:0071459)2.74674217
91negative regulation of histone methylation (GO:0031061)2.74464374
92positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.74165876
93negative regulation of interleukin-17 production (GO:0032700)2.73698309
94translational termination (GO:0006415)2.72253879
95mast cell activation (GO:0045576)2.71711800
96leukocyte aggregation (GO:0070486)2.70447150
97regulation of erythrocyte differentiation (GO:0045646)2.70432124
98leukocyte homeostasis (GO:0001776)2.69985303
99response to protozoan (GO:0001562)2.68989337
100positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.68553680
101leukocyte degranulation (GO:0043299)2.67689034
102neutrophil mediated immunity (GO:0002446)2.66080541
103germinal center formation (GO:0002467)2.65719301
104T-helper 1 type immune response (GO:0042088)2.65062400
105angiogenesis involved in wound healing (GO:0060055)2.64097461
106natural killer cell differentiation (GO:0001779)2.63801051
107neutrophil activation (GO:0042119)2.63390812
108natural killer cell activation involved in immune response (GO:0002323)2.62715540
109regulation of T-helper 1 cell differentiation (GO:0045625)2.62602853
110positive regulation of regulated secretory pathway (GO:1903307)2.62476883
111defense response to protozoan (GO:0042832)2.61657281
112positive regulation of tumor necrosis factor production (GO:0032760)2.61420112
113positive regulation of macrophage differentiation (GO:0045651)2.61364288
114DNA duplex unwinding (GO:0032508)2.61226586
115myeloid dendritic cell activation (GO:0001773)2.59142151
116DNA replication initiation (GO:0006270)2.58933815
117positive regulation of toll-like receptor signaling pathway (GO:0034123)2.58692097
118superoxide anion generation (GO:0042554)2.58578739
119DNA geometric change (GO:0032392)2.58476477
120regulation of interleukin-17 production (GO:0032660)2.57771892
121platelet aggregation (GO:0070527)2.56852540
122myeloid leukocyte activation (GO:0002274)2.56726942
123negative regulation of T cell mediated immunity (GO:0002710)2.54633831
124interferon-gamma-mediated signaling pathway (GO:0060333)2.54273629
125negative regulation of B cell proliferation (GO:0030889)2.54031845
126negative regulation of cytokine production involved in immune response (GO:0002719)2.52920270
127translesion synthesis (GO:0019985)2.51785997
128telomere maintenance via telomere lengthening (GO:0010833)2.51558736
129nucleotide-excision repair, DNA gap filling (GO:0006297)2.51244320
1303-UTR-mediated mRNA stabilization (GO:0070935)2.50642578
131B cell homeostasis (GO:0001782)2.50377329
132IMP biosynthetic process (GO:0006188)2.49662229
133histamine secretion (GO:0001821)2.49162264
134glycosphingolipid catabolic process (GO:0046479)2.48833323
135positive regulation of protein deacetylation (GO:0090312)2.48760200
136adenosine receptor signaling pathway (GO:0001973)2.48240562
137respiratory burst (GO:0045730)2.47571781
138translational elongation (GO:0006414)2.47535563
139SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.47449731
140regulation of dendritic cell antigen processing and presentation (GO:0002604)2.47372215
141B cell differentiation (GO:0030183)2.47116330
142regulation of hypersensitivity (GO:0002883)2.46646610
143production of molecular mediator involved in inflammatory response (GO:0002532)2.44168541
144B cell activation (GO:0042113)2.43977019
145telomere maintenance (GO:0000723)2.42780254
146mitochondrial DNA replication (GO:0006264)2.42172621
147embryonic hemopoiesis (GO:0035162)2.41718938
148negative regulation of RNA splicing (GO:0033119)2.41628791
149erythrocyte maturation (GO:0043249)2.41081420
150regulation of interleukin-12 biosynthetic process (GO:0045075)2.40225974
151B cell mediated immunity (GO:0019724)2.39998197
152telomere organization (GO:0032200)2.38535495
153pentose-phosphate shunt (GO:0006098)2.38276042
154cotranslational protein targeting to membrane (GO:0006613)2.37707335
155protein targeting to ER (GO:0045047)2.37467816
156pinocytosis (GO:0006907)2.36376619
157response to fungus (GO:0009620)2.35863125
158regulation of interferon-beta biosynthetic process (GO:0045357)2.35508535
159response to interferon-beta (GO:0035456)2.34894292
160nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.34396435
161regulation of B cell apoptotic process (GO:0002902)2.34369666
162negative regulation of erythrocyte differentiation (GO:0045647)2.33923892
163cellular response to zinc ion (GO:0071294)2.33676615
164dosage compensation (GO:0007549)2.33495882
165positive regulation of histone H3-K4 methylation (GO:0051571)2.32912430
166regulation of granulocyte differentiation (GO:0030852)2.32783945
167regulation of DNA endoreduplication (GO:0032875)2.32259679
168regulation of mast cell degranulation (GO:0043304)2.32143237
169mitotic sister chromatid cohesion (GO:0007064)2.31080578
170lymph node development (GO:0048535)2.30727299
171meiotic chromosome segregation (GO:0045132)2.30702384
172regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.29896133
173pyrimidine nucleoside salvage (GO:0043097)2.29030078
174pyrimidine-containing compound salvage (GO:0008655)2.29030078
175execution phase of apoptosis (GO:0097194)2.28805113
176B cell proliferation (GO:0042100)2.28112127

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.01840908
2IRF8_22096565_ChIP-ChIP_GC-B_Human3.88188225
3SCL_19346495_ChIP-Seq_HPC-7_Human3.37920670
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.33292562
5MYC_22102868_ChIP-Seq_BL_Human3.23307077
6MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.05783252
7IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.03594652
8* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.01229605
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.98921808
10SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.82142319
11E2F4_17652178_ChIP-ChIP_JURKAT_Human2.79770583
12GATA1_19941826_ChIP-Seq_K562_Human2.67873847
13VDR_21846776_ChIP-Seq_THP-1_Human2.60417645
14SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.58862944
15EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.56356485
16SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human2.50260011
17IRF8_21731497_ChIP-ChIP_J774_Mouse2.50187651
18FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.47754364
19STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.45401795
20MYB_21317192_ChIP-Seq_ERMYB_Mouse2.32397699
21VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.30865116
22VDR_24787735_ChIP-Seq_THP-1_Human2.27587053
23FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.26500342
24RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.15139449
25ELF1_17652178_ChIP-ChIP_JURKAT_Human2.15035947
26GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human2.11566863
27SPI1_23547873_ChIP-Seq_NB4_Human2.11331100
28TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.10720256
29* GATA2_19941826_ChIP-Seq_K562_Human2.07984568
30GATA2_21666600_ChIP-Seq_HMVEC_Human2.04371720
31FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.01387250
32BP1_19119308_ChIP-ChIP_Hs578T_Human2.00881963
33ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.98965976
34MYB_26560356_Chip-Seq_TH2_Human1.95735979
35FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.92136222
36MYC_18555785_ChIP-Seq_MESCs_Mouse1.90410967
37CIITA_25753668_ChIP-Seq_RAJI_Human1.88936021
38GATA1_22025678_ChIP-Seq_K562_Human1.88781155
39RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.86908891
40* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.85878631
41* IRF8_27001747_Chip-Seq_BMDM_Mouse1.85356007
42* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.84547319
43HOXB4_20404135_ChIP-ChIP_EML_Mouse1.82953379
44MYB_26560356_Chip-Seq_TH1_Human1.81453656
45VDR_24763502_ChIP-Seq_THP-1_Human1.81014566
46MAF_26560356_Chip-Seq_TH1_Human1.77982726
47SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.73626682
48ERG_20887958_ChIP-Seq_HPC-7_Mouse1.73020550
49BRD4_27068464_Chip-Seq_AML-cells_Mouse1.72583999
50RUNX1_22412390_ChIP-Seq_EML_Mouse1.71671191
51* UTX_26944678_Chip-Seq_JUKART_Human1.70418339
52STAT4_19710469_ChIP-ChIP_TH1__Mouse1.68273787
53STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.68086037
54SMAD_19615063_ChIP-ChIP_OVARY_Human1.63255835
55TCF7_22412390_ChIP-Seq_EML_Mouse1.61205868
56* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.60387159
57FOXP3_21729870_ChIP-Seq_TREG_Human1.60220440
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.59063477
59IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.56843656
60FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.56662956
61E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.54008335
62VDR_23849224_ChIP-Seq_CD4+_Human1.51900633
63* NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.51889387
64GATA1_22383799_ChIP-Seq_G1ME_Mouse1.51021179
65NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.49964609
66LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.49182380
67* PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.49157069
68MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.47207603
69GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.46374417
70SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.45012379
71GATA2_22383799_ChIP-Seq_G1ME_Mouse1.44585751
72* RUNX_20019798_ChIP-Seq_JUKART_Human1.43853838
73STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.38481069
74TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.37225176
75MYC_19030024_ChIP-ChIP_MESCs_Mouse1.35533968
76EST1_17652178_ChIP-ChIP_JURKAT_Human1.33836491
77NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.33576571
78KDM2B_26808549_Chip-Seq_SUP-B15_Human1.32328687
79MYC_18358816_ChIP-ChIP_MESCs_Mouse1.30329371
80NOTCH1_21737748_ChIP-Seq_TLL_Human1.28918724
81* SPI1_23127762_ChIP-Seq_K562_Human1.24098849
82FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.22286359
83LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.21000806
84MYC_19079543_ChIP-ChIP_MESCs_Mouse1.20542152
85TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.19330388
86MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.19115164
87NELFA_20434984_ChIP-Seq_ESCs_Mouse1.18177121
88TP63_19390658_ChIP-ChIP_HaCaT_Human1.16938355
89GABP_17652178_ChIP-ChIP_JURKAT_Human1.16529355
90ELK1_19687146_ChIP-ChIP_HELA_Human1.16396380
91IKZF1_21737484_ChIP-ChIP_HCT116_Human1.15975269
92TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15533099
93XRN2_22483619_ChIP-Seq_HELA_Human1.15253671
94* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.14185043
95NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.14075936
96GATA1_19941827_ChIP-Seq_MEL_Mouse1.12204725
97PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.11180805
98MAF_26560356_Chip-Seq_TH2_Human1.08489332
99KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.07851292
100MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.07389286
101CDX2_19796622_ChIP-Seq_MESCs_Mouse1.05586930
102PU_27001747_Chip-Seq_BMDM_Mouse1.03733274
103GATA1_19941827_ChIP-Seq_MEL86_Mouse1.03698595
104KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.02907285
105CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.02653633
106* ELK3_25401928_ChIP-Seq_HUVEC_Human1.02085419
107CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.01750768
108ETS1_20019798_ChIP-Seq_JURKAT_Human1.01077135
109CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00133293
110* GATA3_26560356_Chip-Seq_TH2_Human0.99464744
111* GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.99014031
112KDM5A_27292631_Chip-Seq_BREAST_Human0.98812078
113GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98682486
114STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.97839841
115LXR_22158963_ChIP-Seq_LIVER_Mouse0.97480292
116KDM2B_26808549_Chip-Seq_DND41_Human0.96852336
117ETS1_22383799_ChIP-Seq_G1ME_Mouse0.95973409
118HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.95238269
119* GATA3_27048872_Chip-Seq_THYMUS_Human0.94785300
120CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.92972318
121KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.92548590
122* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92252714
123SALL4_18804426_ChIP-ChIP_XEN_Mouse0.92164712
124JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.91046000
125TFEB_21752829_ChIP-Seq_HELA_Human0.90353987
126PU.1_20513432_ChIP-Seq_Bcells_Mouse0.88586630
127MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.87212967
128E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.86939805
129* NCOR1_26117541_ChIP-Seq_K562_Human0.86361934
130CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.86228362
131GABP_19822575_ChIP-Seq_HepG2_Human0.85962977
132RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.85937859
133STAT6_21828071_ChIP-Seq_BEAS2B_Human0.82700100
134* RXR_22158963_ChIP-Seq_LIVER_Mouse0.82137961
135ELK4_26923725_Chip-Seq_MESODERM_Mouse0.77386666
136KDM2B_26808549_Chip-Seq_JURKAT_Human0.77211469
137SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.77164078
138PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.75812976
139RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75755328
140FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.74837338
141SMRT_27268052_Chip-Seq_Bcells_Human0.73357096
142KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.71494384
143VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.70319401
144JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.68136251
145PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.67928675
146BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.66796105

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.83369805
2MP0002396_abnormal_hematopoietic_system3.62137790
3MP0001800_abnormal_humoral_immune2.86958797
4MP0004808_abnormal_hematopoietic_stem2.80940554
5MP0000685_abnormal_immune_system2.76395239
6MP0005671_abnormal_response_to2.64897463
7MP0008004_abnormal_stomach_pH2.62540079
8MP0002398_abnormal_bone_marrow2.54545813
9MP0002452_abnormal_antigen_presenting2.50324766
10MP0005464_abnormal_platelet_physiology2.45925554
11MP0001790_abnormal_immune_system2.42770855
12MP0005387_immune_system_phenotype2.42770855
13MP0003436_decreased_susceptibility_to2.41051994
14MP0008057_abnormal_DNA_replication2.38609855
15MP0009785_altered_susceptibility_to2.37550176
16MP0010094_abnormal_chromosome_stability2.36352063
17MP0005397_hematopoietic_system_phenotyp2.35243783
18MP0001545_abnormal_hematopoietic_system2.35243783
19MP0002420_abnormal_adaptive_immunity2.30122320
20MP0005000_abnormal_immune_tolerance2.27899569
21MP0001819_abnormal_immune_cell2.27432201
22MP0003693_abnormal_embryo_hatching2.26641190
23MP0002723_abnormal_immune_serum2.25362689
24MP0000689_abnormal_spleen_morphology2.20521887
25MP0009278_abnormal_bone_marrow2.17005904
26MP0003303_peritoneal_inflammation2.16713450
27MP0005025_abnormal_response_to2.15703858
28MP0000716_abnormal_immune_system2.14762822
29MP0002419_abnormal_innate_immunity2.08008522
30MP0002722_abnormal_immune_system2.07996365
31MP0000465_gastrointestinal_hemorrhage2.02751631
32MP0003763_abnormal_thymus_physiology1.96385170
33MP0002429_abnormal_blood_cell1.95301783
34MP0006054_spinal_hemorrhage1.92018887
35MP0002166_altered_tumor_susceptibility1.87996115
36MP0002148_abnormal_hypersensitivity_rea1.86043529
37MP0003111_abnormal_nucleus_morphology1.83488320
38MP0003077_abnormal_cell_cycle1.81294066
39MP0005451_abnormal_body_composition1.78244955
40MP0005174_abnormal_tail_pigmentation1.77675518
41MP0004510_myositis1.76210091
42MP0000490_abnormal_crypts_of1.73704300
43MP0000703_abnormal_thymus_morphology1.70077316
44MP0002405_respiratory_system_inflammati1.69246713
45MP0010155_abnormal_intestine_physiology1.68409362
46MP0004883_abnormal_blood_vessel1.59543752
47MP0009333_abnormal_splenocyte_physiolog1.57887483
48MP0008058_abnormal_DNA_repair1.56304834
49MP0002998_abnormal_bone_remodeling1.55827826
50MP0008007_abnormal_cellular_replicative1.53558101
51MP0001853_heart_inflammation1.53045293
52MP0003300_gastrointestinal_ulcer1.52570896
53MP0001873_stomach_inflammation1.51333933
54MP0003075_altered_response_to1.50655268
55MP0001845_abnormal_inflammatory_respons1.48772084
56MP0003724_increased_susceptibility_to1.46444963
57MP0005075_abnormal_melanosome_morpholog1.46400663
58MP0002006_tumorigenesis1.46330874
59MP0002132_abnormal_respiratory_system1.45225976
60MP0010307_abnormal_tumor_latency1.40152939
61MP0004957_abnormal_blastocyst_morpholog1.39744334
62MP0002019_abnormal_tumor_incidence1.39440630
63MP0010352_gastrointestinal_tract_polyps1.32573547
64MP0003091_abnormal_cell_migration1.32012637
65MP0005164_abnormal_response_to1.31796342
66MP0002095_abnormal_skin_pigmentation1.30600136
67MP0003656_abnormal_erythrocyte_physiolo1.27640060
68MP0002877_abnormal_melanocyte_morpholog1.23555822
69MP0004947_skin_inflammation1.18970306
70MP0003690_abnormal_glial_cell1.16308177
71MP0000015_abnormal_ear_pigmentation1.12692317
72MP0003866_abnormal_defecation1.12547604
73MP0008469_abnormal_protein_level1.09936610
74MP0001851_eye_inflammation1.08851562
75MP0006082_CNS_inflammation1.07264581
76MP0000249_abnormal_blood_vessel1.07152122
77MP0003183_abnormal_peptide_metabolism1.06367861
78MP0003191_abnormal_cellular_cholesterol1.05335608
79MP0003943_abnormal_hepatobiliary_system1.04426624
80MP0005083_abnormal_biliary_tract1.03674593
81MP0000604_amyloidosis1.02275663
82MP0005310_abnormal_salivary_gland1.00343238
83MP0000313_abnormal_cell_death0.99565367
84MP0004147_increased_porphyrin_level0.98689065
85MP0001986_abnormal_taste_sensitivity0.98291114
86MP0002332_abnormal_exercise_endurance0.94543609
87MP0008260_abnormal_autophagy0.94538179
88MP0001533_abnormal_skeleton_physiology0.93889633
89MP0005167_abnormal_blood-brain_barrier0.91935919
90MP0009764_decreased_sensitivity_to0.89011809
91MP0003172_abnormal_lysosome_physiology0.86964924
92MP0005390_skeleton_phenotype0.86506797
93MP0000350_abnormal_cell_proliferation0.86021292
94MP0000858_altered_metastatic_potential0.84763696
95MP0005166_decreased_susceptibility_to0.83179276
96MP0008874_decreased_physiological_sensi0.82955196
97MP0002928_abnormal_bile_duct0.82876783
98MP0005084_abnormal_gallbladder_morpholo0.81574273
99MP0003795_abnormal_bone_structure0.79344030
100MP0003828_pulmonary_edema0.76461903
101MP0003786_premature_aging0.76232839
102MP0003787_abnormal_imprinting0.76175619
103MP0008877_abnormal_DNA_methylation0.75645080
104MP0000569_abnormal_digit_pigmentation0.72941004
105MP0002139_abnormal_hepatobiliary_system0.71650416
106MP0005165_increased_susceptibility_to0.71367777
107MP0002933_joint_inflammation0.70343272
108MP0000598_abnormal_liver_morphology0.69617451
109MP0009763_increased_sensitivity_to0.68757208
110MP0003448_altered_tumor_morphology0.66411707
111MP0003453_abnormal_keratinocyte_physiol0.65934497
112MP0002693_abnormal_pancreas_physiology0.65151410
113MP0005381_digestive/alimentary_phenotyp0.64920843
114MP0003567_abnormal_fetal_cardiomyocyte0.63814609
115MP0001663_abnormal_digestive_system0.63310792
116MP0005365_abnormal_bile_salt0.62908670
117MP0000371_diluted_coat_color0.60983046
118MP0005535_abnormal_body_temperature0.60855321
119MP0005058_abnormal_lysosome_morphology0.60819445
120MP0009765_abnormal_xenobiotic_induced0.60635782
121MP0003638_abnormal_response/metabolism_0.59953672
122MP0010329_abnormal_lipoprotein_level0.59454530
123MP0001915_intracranial_hemorrhage0.58884680
124MP0001879_abnormal_lymphatic_vessel0.58425794
125MP0000609_abnormal_liver_physiology0.58300718
126MP0000230_abnormal_systemic_arterial0.58007793
127MP0008873_increased_physiological_sensi0.57977302
128MP0009840_abnormal_foam_cell0.57018381
129MP0005319_abnormal_enzyme/_coenzyme0.56950524
130MP0003566_abnormal_cell_adhesion0.56581662
131MP0004264_abnormal_extraembryonic_tissu0.55847290
132MP0005076_abnormal_cell_differentiation0.55310583
133MP0001958_emphysema0.55101255
134MP0000343_altered_response_to0.52881610
135MP0002075_abnormal_coat/hair_pigmentati0.52586814

Predicted human phenotypes

RankGene SetZ-score
1Agammaglobulinemia (HP:0004432)5.26535799
2Cellulitis (HP:0100658)5.12823886
3Menorrhagia (HP:0000132)4.79085513
4Increased mean platelet volume (HP:0011877)4.55315502
5IgM deficiency (HP:0002850)4.46875024
6Recurrent viral infections (HP:0004429)4.25445553
7Abnormality of glycolipid metabolism (HP:0010969)4.02776543
8Abnormality of liposaccharide metabolism (HP:0010968)4.02776543
9Abnormality of glycosphingolipid metabolism (HP:0004343)4.02776543
10Meningitis (HP:0001287)4.02741366
11Recurrent abscess formation (HP:0002722)3.92379103
12Thrombocytosis (HP:0001894)3.85499158
13B lymphocytopenia (HP:0010976)3.83783315
14Abnormality of B cell number (HP:0010975)3.83783315
15Dysostosis multiplex (HP:0000943)3.81795826
16Chronic otitis media (HP:0000389)3.75572097
17Recurrent bronchitis (HP:0002837)3.72985883
18Prolonged bleeding time (HP:0003010)3.71054181
19Panhypogammaglobulinemia (HP:0003139)3.70181763
20Recurrent bacterial skin infections (HP:0005406)3.69023975
21Petechiae (HP:0000967)3.68101381
22Recurrent fungal infections (HP:0002841)3.60039050
23Abnormal delayed hypersensitivity skin test (HP:0002963)3.57266883
24Verrucae (HP:0200043)3.50225051
25Papilloma (HP:0012740)3.50225051
26Vacuolated lymphocytes (HP:0001922)3.48861721
27Myositis (HP:0100614)3.35258381
28Thyroiditis (HP:0100646)3.29073403
29Eczematoid dermatitis (HP:0000976)3.23569647
30Osteomyelitis (HP:0002754)3.22212886
31Increased cerebral lipofuscin (HP:0011813)3.17093484
32Stomatitis (HP:0010280)3.10978317
33Abnormality of T cell physiology (HP:0011840)3.09312861
34Gastrointestinal inflammation (HP:0004386)3.05995470
35Inflammation of the large intestine (HP:0002037)3.03980246
36Colitis (HP:0002583)3.03807654
37Abnormality of the heme biosynthetic pathway (HP:0010472)2.97727502
38Abnormality of the vasculature of the conjunctiva (HP:0008054)2.97584308
39Aplastic anemia (HP:0001915)2.96738695
40Polycythemia (HP:0001901)2.92884083
41Reticulocytopenia (HP:0001896)2.86480380
42Chronic sinusitis (HP:0011109)2.80571395
43Elevated erythrocyte sedimentation rate (HP:0003565)2.79437186
44Abnormality of T cells (HP:0002843)2.78975512
45Epistaxis (HP:0000421)2.78638208
46Gastrointestinal infarctions (HP:0005244)2.73862450
47Urinary glycosaminoglycan excretion (HP:0003541)2.72018962
48Mucopolysacchariduria (HP:0008155)2.72018962
49Peritonitis (HP:0002586)2.71826698
50Spontaneous hematomas (HP:0007420)2.71733351
51Abnormality of the common coagulation pathway (HP:0010990)2.71523351
52Abnormality of the fingertips (HP:0001211)2.70664240
53Encephalitis (HP:0002383)2.68866039
54Vasculitis (HP:0002633)2.66063424
55Impaired platelet aggregation (HP:0003540)2.65562476
56Abnormal platelet function (HP:0011869)2.65562476
57Myocardial infarction (HP:0001658)2.65510626
58Recurrent pneumonia (HP:0006532)2.65070209
59Recurrent skin infections (HP:0001581)2.64476152
60Episodic fever (HP:0001954)2.64161152
61Abnormality of polysaccharide metabolism (HP:0011012)2.63189626
62Abnormality of glycosaminoglycan metabolism (HP:0004371)2.63189626
63Abnormality of mucopolysaccharide metabolism (HP:0011020)2.63189626
64Hypoplasia of the thymus (HP:0000778)2.62724051
65Lymphopenia (HP:0001888)2.62719283
66Mediastinal lymphadenopathy (HP:0100721)2.61744303
67IgG deficiency (HP:0004315)2.60492944
68Abnormality of cells of the lymphoid lineage (HP:0012140)2.59887757
69Myelodysplasia (HP:0002863)2.58849312
70Conjunctival telangiectasia (HP:0000524)2.58045031
71Sepsis (HP:0100806)2.57879903
72Abnormal number of erythroid precursors (HP:0012131)2.56969781
73Increased neuronal autofluorescent lipopigment (HP:0002074)2.56179621
74Loss of speech (HP:0002371)2.54591541
75Abnormality of cells of the erythroid lineage (HP:0012130)2.53869767
76Increased serum ferritin (HP:0003281)2.53250064
77Abnormality of iron homeostasis (HP:0011031)2.51671802
78Gastrointestinal stroma tumor (HP:0100723)2.51517706
79Gingival bleeding (HP:0000225)2.49131119
80Recurrent lower respiratory tract infections (HP:0002783)2.45929065
81Amyloidosis (HP:0011034)2.44891478
82Retrobulbar optic neuritis (HP:0100654)2.44255077
83Optic neuritis (HP:0100653)2.44255077
84Recurrent cutaneous fungal infections (HP:0011370)2.44013769
85Chronic mucocutaneous candidiasis (HP:0002728)2.44013769
86Orchitis (HP:0100796)2.43121639
87Urticaria (HP:0001025)2.42417854
88Chronic obstructive pulmonary disease (HP:0006510)2.41768647
89Obstructive lung disease (HP:0006536)2.41768647
90Recurrent sinusitis (HP:0011108)2.40296364
91Lymphoma (HP:0002665)2.40044543
92Bruising susceptibility (HP:0000978)2.39515075
93Chromsome breakage (HP:0040012)2.39364752
94Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.39357160
95Neutropenia (HP:0001875)2.37944227
96Hypochromic anemia (HP:0001931)2.36922036
97Volvulus (HP:0002580)2.36779741
98Abnormal platelet volume (HP:0011876)2.36201988
99Recurrent gram-negative bacterial infections (HP:0005420)2.35979121
100Gingivitis (HP:0000230)2.35294566
101Periodontitis (HP:0000704)2.35173450
102Abnormality of transition element cation homeostasis (HP:0011030)2.33019393
103IgA deficiency (HP:0002720)2.32569948
104Granulocytopenia (HP:0001913)2.28007953
105Abnormality of the prostate (HP:0008775)2.26479191
106T lymphocytopenia (HP:0005403)2.26465122
107Pulmonary embolism (HP:0002204)2.23935996
108Autoimmune thrombocytopenia (HP:0001973)2.23782812
109Disinhibition (HP:0000734)2.22819710
110Skin rash (HP:0000988)2.21627920
111Chromosomal breakage induced by crosslinking agents (HP:0003221)2.20497605
112Acanthocytosis (HP:0001927)2.19188267
113Facial diplegia (HP:0001349)2.19169703
114Cutaneous melanoma (HP:0012056)2.17877460
115Systemic lupus erythematosus (HP:0002725)2.17622961
116Abnormality of T cell number (HP:0011839)2.17405071
117Arterial thrombosis (HP:0004420)2.16636891
118Acute myeloid leukemia (HP:0004808)2.15472377
119Acute lymphatic leukemia (HP:0006721)2.14454889
120Hematochezia (HP:0002573)2.13753091
121Hyperlipoproteinemia (HP:0010980)2.13608266
122Eosinophilia (HP:0001880)2.12337976
123Pulmonary infiltrates (HP:0002113)2.09370448
124Pallor (HP:0000980)2.09037247
125Hepatosplenomegaly (HP:0001433)2.07433516
126Chest pain (HP:0100749)2.07183109
127Poikilocytosis (HP:0004447)2.07164022
128Abnormality of macrophages (HP:0004311)2.04608397
129Severe combined immunodeficiency (HP:0004430)2.04017947
130Combined immunodeficiency (HP:0005387)2.03499377
131Leukocytosis (HP:0001974)2.00710792
132Keratoconjunctivitis sicca (HP:0001097)2.00075301
133Purpura (HP:0000979)1.98497969
134Skin ulcer (HP:0200042)1.97174879
135Joint hemorrhage (HP:0005261)1.96979523
136Amaurosis fugax (HP:0100576)1.96453700
137Bronchitis (HP:0012387)1.96035098
138Poikiloderma (HP:0001029)1.95185497
139Hemoptysis (HP:0002105)1.94171211
140Mucosal telangiectasiae (HP:0100579)1.93368915
141Leukopenia (HP:0001882)1.93306209
142Interstitial pulmonary disease (HP:0006530)1.92562612
143Clubbing of toes (HP:0100760)1.91475508
144Vertigo (HP:0002321)1.89331443
145Increased IgE level (HP:0003212)1.89197127
146Thrombophlebitis (HP:0004418)1.88879428
147Increased IgM level (HP:0003496)1.85448200
148Abnormality of the peritoneum (HP:0002585)1.82817024
149Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.80483620
150Acne (HP:0001061)1.79133597
151Dyschromatopsia (HP:0007641)1.78080004
152Autoimmune hemolytic anemia (HP:0001890)1.73480942
153Splenomegaly (HP:0001744)1.72866121
154Ventricular fibrillation (HP:0001663)1.72010324

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.63905995
2EEF2K3.63153728
3MAP3K103.23433827
4BTK2.50886388
5GRK62.35447910
6BMPR22.35356627
7IRAK42.17091882
8FGR2.06607506
9BLK2.02235780
10FLT31.97944709
11RPS6KB21.95771075
12SYK1.95340729
13PKN21.93525533
14ERN11.90237886
15CSF1R1.84658604
16KIT1.81455654
17TEC1.80758741
18NEK21.75839223
19TAOK31.71934996
20CDC71.68857512
21GRK71.67161466
22PIM11.63854010
23PIK3CG1.61963646
24STK101.59291893
25STK41.55999619
26TYK21.41074806
27JAK31.40449993
28ZAP701.40276662
29MAP3K141.39833233
30PRPF4B1.38771845
31MATK1.30945731
32CDK41.28606542
33BMX1.27566168
34CLK11.26970934
35TGFBR11.25072696
36LRRK21.24155422
37CAMKK21.23006272
38WEE11.22500047
39LYN1.21486397
40PASK1.21148075
41TGFBR21.21085128
42MAP3K31.20779211
43ZAK1.19938068
44IRAK31.19830175
45SIK21.17814345
46BRD41.17376611
47ATR1.16728526
48MAP2K31.16512547
49MAP3K11.16389931
50FES1.15634443
51IRAK11.14881826
52YES11.12151577
53TBK11.11242418
54IKBKB1.10736171
55ACVR1B1.09990057
56CDK121.08934591
57IKBKE1.06591417
58TNK21.05994971
59MAP3K111.05430420
60RIPK41.05376219
61TLK11.05183326
62EPHB11.03106338
63PDK11.02990489
64TAOK11.01533644
65SCYL21.00405972
66PDPK10.99815032
67HCK0.99580178
68EPHA30.99260735
69VRK10.98347001
70EIF2AK30.97741365
71MKNK10.96335581
72TRPM70.96170189
73PTK2B0.95195410
74FGFR30.92090463
75MAPK110.91641760
76MAP3K20.91577540
77IRAK20.90764668
78TXK0.89733285
79BRSK20.88133639
80PIM20.88113429
81ADRBK20.86467570
82CDK60.84344606
83CDC42BPA0.84316672
84BUB10.83456427
85LCK0.83078493
86TAOK20.80364621
87DYRK1B0.79008540
88MAP3K50.78362107
89CSK0.76277336
90STK240.73644248
91ITK0.72680588
92HIPK20.72225729
93MAPK40.71774358
94MAP3K80.71363138
95CAMK1D0.70035444
96MOS0.69816231
97MARK20.69579598
98KSR20.68827290
99AURKB0.68168604
100RET0.67996585
101MAPKAPK30.67915187
102JAK10.67429960
103FGFR40.64801985
104CDK90.63980543
105MKNK20.63053966
106CDK70.62651962
107CAMK1G0.62121090
108CHUK0.61529247
109MAP3K130.59958832
110CCNB10.59401697
111STK160.58405371
112PDGFRB0.57622738
113RPS6KA40.56070565
114EIF2AK10.52258922
115DYRK30.51970361
116RPS6KB10.51805772
117TESK20.50537701
118ALK0.50460807
119JAK20.49371673
120KDR0.49159807
121SIK30.48484278
122DDR20.48167287
123PLK40.48014722
124SRPK10.47760285
125NLK0.47710352
126NEK90.47483157
127RPS6KA60.47245924
128MARK30.46293257
129FYN0.46012662
130BRSK10.45847120
131MAP2K40.45796367
132CHEK10.45434781
133TRIB30.45218178
134PAK40.44811458
135RAF10.44484371
136MAP3K60.43995989
137PLK10.42446217
138MAP3K120.42256778
139SGK30.41341277
140MAP3K70.39985356
141RPS6KC10.39767753
142KSR10.39090972
143PRKCQ0.38918101
144MAPK70.38180035
145GRK50.36917697
146SGK20.33401995
147MAPK120.33297007
148WNK10.31711676
149ABL10.31460203
150MAP2K10.31381615
151PTK60.31034201
152PRKCD0.30205905
153EPHB20.29806723

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.80499617
2Primary immunodeficiency_Homo sapiens_hsa053403.50545737
3Mismatch repair_Homo sapiens_hsa034302.87161983
4B cell receptor signaling pathway_Homo sapiens_hsa046622.78378792
5Non-homologous end-joining_Homo sapiens_hsa034502.75428077
6Base excision repair_Homo sapiens_hsa034102.72215211
7NF-kappa B signaling pathway_Homo sapiens_hsa040642.12422055
8Ribosome_Homo sapiens_hsa030102.09473402
9Homologous recombination_Homo sapiens_hsa034402.03686217
10Leishmaniasis_Homo sapiens_hsa051402.03144267
11Hematopoietic cell lineage_Homo sapiens_hsa046401.89607315
12Intestinal immune network for IgA production_Homo sapiens_hsa046721.86996699
13Lysosome_Homo sapiens_hsa041421.78417052
14Systemic lupus erythematosus_Homo sapiens_hsa053221.73145696
15Herpes simplex infection_Homo sapiens_hsa051681.70175476
16Measles_Homo sapiens_hsa051621.64836961
17Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.64407757
18Antigen processing and presentation_Homo sapiens_hsa046121.63666410
19Cell cycle_Homo sapiens_hsa041101.61967691
20One carbon pool by folate_Homo sapiens_hsa006701.59844907
21Rheumatoid arthritis_Homo sapiens_hsa053231.56423016
22Spliceosome_Homo sapiens_hsa030401.56083647
23Phagosome_Homo sapiens_hsa041451.52666170
24Nucleotide excision repair_Homo sapiens_hsa034201.51813386
25Transcriptional misregulation in cancer_Homo sapiens_hsa052021.47429398
26RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.45000454
27Pyrimidine metabolism_Homo sapiens_hsa002401.44700480
28Osteoclast differentiation_Homo sapiens_hsa043801.43729342
29Autoimmune thyroid disease_Homo sapiens_hsa053201.43581887
30Fanconi anemia pathway_Homo sapiens_hsa034601.43362769
31Type I diabetes mellitus_Homo sapiens_hsa049401.35664151
32Legionellosis_Homo sapiens_hsa051341.35375344
33Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.35089460
34Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.32275640
35Toll-like receptor signaling pathway_Homo sapiens_hsa046201.29771838
36Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.24722828
37NOD-like receptor signaling pathway_Homo sapiens_hsa046211.20968277
38Acute myeloid leukemia_Homo sapiens_hsa052211.18838990
39Chronic myeloid leukemia_Homo sapiens_hsa052201.16909976
40Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.16440815
41Viral carcinogenesis_Homo sapiens_hsa052031.15105082
42Influenza A_Homo sapiens_hsa051641.14067571
43Hepatitis B_Homo sapiens_hsa051611.13685468
44Drug metabolism - other enzymes_Homo sapiens_hsa009831.11687723
45Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.11403006
46Non-small cell lung cancer_Homo sapiens_hsa052231.10248108
47Other glycan degradation_Homo sapiens_hsa005111.08781222
48Jak-STAT signaling pathway_Homo sapiens_hsa046301.08404576
49Platelet activation_Homo sapiens_hsa046111.07858577
50Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.07668391
51Pentose phosphate pathway_Homo sapiens_hsa000301.04886620
52Complement and coagulation cascades_Homo sapiens_hsa046101.03834346
53Apoptosis_Homo sapiens_hsa042101.02553242
54Shigellosis_Homo sapiens_hsa051311.02413379
55RNA transport_Homo sapiens_hsa030131.00736485
56Tuberculosis_Homo sapiens_hsa051520.99503903
57African trypanosomiasis_Homo sapiens_hsa051430.98397082
58SNARE interactions in vesicular transport_Homo sapiens_hsa041300.97705478
59Selenocompound metabolism_Homo sapiens_hsa004500.97559548
60Epstein-Barr virus infection_Homo sapiens_hsa051690.94928925
61p53 signaling pathway_Homo sapiens_hsa041150.93958031
62Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.92920608
63Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.92720018
64Toxoplasmosis_Homo sapiens_hsa051450.91252072
65Pertussis_Homo sapiens_hsa051330.90398927
66RNA degradation_Homo sapiens_hsa030180.90387729
67Prolactin signaling pathway_Homo sapiens_hsa049170.89914311
68Amoebiasis_Homo sapiens_hsa051460.89907802
69Renal cell carcinoma_Homo sapiens_hsa052110.88683039
70Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.88624307
71Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.87490096
72Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.86309568
73Chemokine signaling pathway_Homo sapiens_hsa040620.86277324
74N-Glycan biosynthesis_Homo sapiens_hsa005100.85976901
75Caffeine metabolism_Homo sapiens_hsa002320.85502260
76Type II diabetes mellitus_Homo sapiens_hsa049300.83831727
77Asthma_Homo sapiens_hsa053100.82904223
78VEGF signaling pathway_Homo sapiens_hsa043700.81789732
79Sphingolipid signaling pathway_Homo sapiens_hsa040710.79747222
80Staphylococcus aureus infection_Homo sapiens_hsa051500.79718905
81Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.79230179
82Adipocytokine signaling pathway_Homo sapiens_hsa049200.78615161
83Leukocyte transendothelial migration_Homo sapiens_hsa046700.78181947
84Viral myocarditis_Homo sapiens_hsa054160.76628700
85Allograft rejection_Homo sapiens_hsa053300.73948360
86Glycosaminoglycan degradation_Homo sapiens_hsa005310.71899381
87HTLV-I infection_Homo sapiens_hsa051660.71322458
88Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.69440050
89Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.69272600
90Pancreatic cancer_Homo sapiens_hsa052120.67152401
91Small cell lung cancer_Homo sapiens_hsa052220.66922553
92Malaria_Homo sapiens_hsa051440.65848485
93Phospholipase D signaling pathway_Homo sapiens_hsa040720.65756468
94Dorso-ventral axis formation_Homo sapiens_hsa043200.65487010
95Notch signaling pathway_Homo sapiens_hsa043300.64399748
96RNA polymerase_Homo sapiens_hsa030200.63910003
97T cell receptor signaling pathway_Homo sapiens_hsa046600.63424470
98mRNA surveillance pathway_Homo sapiens_hsa030150.63178872
99Alcoholism_Homo sapiens_hsa050340.61618982
100Bladder cancer_Homo sapiens_hsa052190.61514512
101Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60742128
102Endocytosis_Homo sapiens_hsa041440.60233081
103TNF signaling pathway_Homo sapiens_hsa046680.60103824
104Endometrial cancer_Homo sapiens_hsa052130.59278164
105Sphingolipid metabolism_Homo sapiens_hsa006000.59234018
106Collecting duct acid secretion_Homo sapiens_hsa049660.58521892
107Neurotrophin signaling pathway_Homo sapiens_hsa047220.58097932
108Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.57882462
109HIF-1 signaling pathway_Homo sapiens_hsa040660.57078964
110Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.56942428
111Carbohydrate digestion and absorption_Homo sapiens_hsa049730.56382333
112Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.55298943
113mTOR signaling pathway_Homo sapiens_hsa041500.54547469
114Hepatitis C_Homo sapiens_hsa051600.52803298
115Regulation of actin cytoskeleton_Homo sapiens_hsa048100.52399077
116Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.52069267
117Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.51969262
118Phosphatidylinositol signaling system_Homo sapiens_hsa040700.51317111
119ABC transporters_Homo sapiens_hsa020100.49337263
120Choline metabolism in cancer_Homo sapiens_hsa052310.48142496
121Sulfur relay system_Homo sapiens_hsa041220.48076810
122ErbB signaling pathway_Homo sapiens_hsa040120.47867565
123Purine metabolism_Homo sapiens_hsa002300.46022019
124Basal transcription factors_Homo sapiens_hsa030220.45921434
125Salmonella infection_Homo sapiens_hsa051320.45420988
126Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.45289573
127GnRH signaling pathway_Homo sapiens_hsa049120.44851607
128Rap1 signaling pathway_Homo sapiens_hsa040150.44364302
129Focal adhesion_Homo sapiens_hsa045100.43716760
130Graft-versus-host disease_Homo sapiens_hsa053320.43441029
131Galactose metabolism_Homo sapiens_hsa000520.43208972
132Lysine degradation_Homo sapiens_hsa003100.39513351
133Thyroid cancer_Homo sapiens_hsa052160.39068721
134Folate biosynthesis_Homo sapiens_hsa007900.37730773
135FoxO signaling pathway_Homo sapiens_hsa040680.36149614
136AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.35759964
137Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.35401341
138Colorectal cancer_Homo sapiens_hsa052100.35364254
139Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.35161650
140MicroRNAs in cancer_Homo sapiens_hsa052060.35009490
141Pentose and glucuronate interconversions_Homo sapiens_hsa000400.34294536

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