SUSD3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G7.22955056
2regulation of B cell receptor signaling pathway (GO:0050855)5.90656182
3positive regulation of gamma-delta T cell activation (GO:0046645)5.19501273
4negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.19300254
5negative regulation of cell killing (GO:0031342)5.19300254
6immunoglobulin mediated immune response (GO:0016064)4.89339098
7regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.79000340
8antigen processing and presentation of endogenous antigen (GO:0019883)4.69674494
9regulation of interferon-beta biosynthetic process (GO:0045357)4.54684136
10positive regulation of B cell differentiation (GO:0045579)4.53761790
11modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.44924789
12positive regulation by organism of defense response of other organism involved in symbiotic interact4.44924789
13modulation by symbiont of host immune response (GO:0052553)4.44924789
14positive regulation by symbiont of host defense response (GO:0052509)4.44924789
15modulation by symbiont of host defense response (GO:0052031)4.44924789
16modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.44924789
17microglial cell activation (GO:0001774)4.35155547
18antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.32455429
19antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.32455429
20B cell receptor signaling pathway (GO:0050853)4.20365646
21regulation of B cell differentiation (GO:0045577)4.19265455
22positive regulation of antigen processing and presentation (GO:0002579)4.18565705
23G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)4.14617174
24macrophage activation involved in immune response (GO:0002281)4.13983176
25mature B cell differentiation involved in immune response (GO:0002313)4.09060261
26T cell selection (GO:0045058)4.02156211
27thymic T cell selection (GO:0045061)4.01771128
28positive T cell selection (GO:0043368)4.00436322
29regulation of interleukin-12 biosynthetic process (GO:0045075)3.92693904
30leukocyte aggregation (GO:0070486)3.91217256
31mast cell activation (GO:0045576)3.91016875
32antigen processing and presentation via MHC class Ib (GO:0002475)3.89551705
33mature B cell differentiation (GO:0002335)3.89386692
34positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.89156664
35detection of bacterium (GO:0016045)3.85709996
36response to interleukin-15 (GO:0070672)3.82559587
37B cell mediated immunity (GO:0019724)3.80310408
38regulation of alpha-beta T cell proliferation (GO:0046640)3.71863753
39positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.71678095
40positive regulation of interferon-alpha production (GO:0032727)3.71050020
41neutrophil activation involved in immune response (GO:0002283)3.66986580
42detection of other organism (GO:0098543)3.64553607
43cellular response to interleukin-15 (GO:0071350)3.64303761
44regulation of gamma-delta T cell differentiation (GO:0045586)3.62042660
45positive regulation of isotype switching (GO:0045830)3.59554952
46regulation of interferon-alpha production (GO:0032647)3.57004945
47regulation of regulatory T cell differentiation (GO:0045589)3.55696565
48regulation of rhodopsin mediated signaling pathway (GO:0022400)3.52840819
49positive regulation of alpha-beta T cell proliferation (GO:0046641)3.52039090
50positive thymic T cell selection (GO:0045059)3.49595408
51regulation of antigen processing and presentation (GO:0002577)3.48297041
52negative regulation of granulocyte differentiation (GO:0030853)3.48022129
53positive regulation of granulocyte differentiation (GO:0030854)3.45298134
54regulation of gamma-delta T cell activation (GO:0046643)3.44364260
55respiratory burst (GO:0045730)3.41952549
56interferon-gamma-mediated signaling pathway (GO:0060333)3.39836018
57regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.38881754
58response to muramyl dipeptide (GO:0032495)3.38622258
59antigen receptor-mediated signaling pathway (GO:0050851)3.37258547
60myeloid cell activation involved in immune response (GO:0002275)3.36290403
61pinocytosis (GO:0006907)3.36122560
62rhodopsin mediated signaling pathway (GO:0016056)3.35193851
63regulation of female gonad development (GO:2000194)3.30545994
64myeloid dendritic cell activation (GO:0001773)3.27664868
65cellular response to type I interferon (GO:0071357)3.25646505
66type I interferon signaling pathway (GO:0060337)3.25646505
67negative regulation of T cell mediated immunity (GO:0002710)3.25314313
68negative regulation of lymphocyte mediated immunity (GO:0002707)3.24668457
69positive regulation of T cell differentiation in thymus (GO:0033089)3.24329470
70response to type I interferon (GO:0034340)3.23871258
71negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.23553969
72negative regulation of macrophage differentiation (GO:0045650)3.23198980
73positive regulation of DNA recombination (GO:0045911)3.22455622
74response to peptidoglycan (GO:0032494)3.20370813
75positive regulation of immunoglobulin mediated immune response (GO:0002891)3.19753389
76positive regulation of B cell mediated immunity (GO:0002714)3.19753389
77defense response to protozoan (GO:0042832)3.19182868
78regulation of isotype switching to IgG isotypes (GO:0048302)3.15813219
79glycosphingolipid catabolic process (GO:0046479)3.14787328
80leukocyte degranulation (GO:0043299)3.14050311
81macrophage activation (GO:0042116)3.13274942
82regulation of T cell tolerance induction (GO:0002664)3.10000231
83response to protozoan (GO:0001562)3.09605137
84Arp2/3 complex-mediated actin nucleation (GO:0034314)3.07532650
85response to interferon-beta (GO:0035456)3.07420994
86regulation of T cell mediated cytotoxicity (GO:0001914)3.07152240
87positive regulation of humoral immune response (GO:0002922)3.06798562
88positive regulation of interleukin-4 production (GO:0032753)3.06516033
89cellular response to zinc ion (GO:0071294)3.06411948
90positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.05987453
91regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.05911449
92T cell receptor signaling pathway (GO:0050852)3.03769802
93myeloid dendritic cell differentiation (GO:0043011)3.02421363
94negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.02370217
95negative regulation of T-helper cell differentiation (GO:0045623)3.02370217
96regulation of macrophage differentiation (GO:0045649)3.01274976
97activated T cell proliferation (GO:0050798)3.00912907
98cellular response to interferon-beta (GO:0035458)2.98988454
99granulocyte activation (GO:0036230)2.96933410
100oligosaccharide catabolic process (GO:0009313)2.96757997
101lymphocyte homeostasis (GO:0002260)2.95298285
102positive regulation of T cell mediated cytotoxicity (GO:0001916)2.94436163
103regulation of granulocyte differentiation (GO:0030852)2.93006075
104negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.92263345
105negative regulation of leukocyte mediated immunity (GO:0002704)2.91832742
106regulation of mast cell degranulation (GO:0043304)2.90862003
107regulation of mast cell activation (GO:0033003)2.90850721
108myeloid leukocyte activation (GO:0002274)2.89434470
109regulation of dendritic cell antigen processing and presentation (GO:0002604)2.88767054
110positive regulation of chemokine secretion (GO:0090197)2.87067496
111positive regulation of macrophage differentiation (GO:0045651)2.85330246
112cytidine metabolic process (GO:0046087)2.85092348
113cytidine catabolic process (GO:0006216)2.85092348
114cytidine deamination (GO:0009972)2.85092348
115regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.83537104
116regulation of natural killer cell mediated immunity (GO:0002715)2.83537104
117response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.83476767
118response to host (GO:0075136)2.83476767
119response to host defenses (GO:0052200)2.83476767
120regulation of interleukin-2 biosynthetic process (GO:0045076)2.83294274
121neutrophil activation (GO:0042119)2.82971026
122positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.81759821
123positive regulation of immunoglobulin production (GO:0002639)2.81008737
124positive regulation of interferon-beta production (GO:0032728)2.80214537
125T cell homeostasis (GO:0043029)2.79135188
126negative regulation of metanephros development (GO:0072217)2.78780174
127NIK/NF-kappaB signaling (GO:0038061)2.78167156
128positive regulation of mast cell activation (GO:0033005)2.78165933
129regulation of tolerance induction (GO:0002643)2.77683365
130T cell costimulation (GO:0031295)2.77326308
131regulation of mast cell activation involved in immune response (GO:0033006)2.77324283
132negative T cell selection (GO:0043383)2.76812499
133negative regulation of T cell apoptotic process (GO:0070233)2.76501195
134positive regulation of B cell activation (GO:0050871)2.76275303
135glycolipid catabolic process (GO:0019377)2.76093764
136megakaryocyte development (GO:0035855)2.75705973
137negative thymic T cell selection (GO:0045060)2.75288389
138response to host immune response (GO:0052572)2.75235818
139response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.75235818
140purinergic nucleotide receptor signaling pathway (GO:0035590)2.75016949
141lymphocyte costimulation (GO:0031294)2.73961837
142cellular extravasation (GO:0045123)2.73493281
143dendritic cell differentiation (GO:0097028)2.73285142
144cellular response to thyroid hormone stimulus (GO:0097067)2.72879254
145regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.72338108
146regulation of interleukin-4 production (GO:0032673)2.72321631
147retinal cone cell development (GO:0046549)2.72042660
148tolerance induction (GO:0002507)2.69485201
149negative regulation of erythrocyte differentiation (GO:0045647)2.69481993
150G-protein coupled purinergic receptor signaling pathway (GO:0035588)2.67095794
151lymphocyte mediated immunity (GO:0002449)2.66196485
152T cell migration (GO:0072678)2.65812085
153ribosomal small subunit assembly (GO:0000028)2.65644867
154mast cell activation involved in immune response (GO:0002279)2.65437612
155mast cell degranulation (GO:0043303)2.65437612

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.32992644
2IRF8_21731497_ChIP-ChIP_J774_Mouse5.22813978
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.44412151
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.89363626
5MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.72389293
6IRF8_27001747_Chip-Seq_BMDM_Mouse3.65895267
7SCL_19346495_ChIP-Seq_HPC-7_Human3.64819063
8* SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.47769837
9BP1_19119308_ChIP-ChIP_Hs578T_Human3.32375339
10STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.26188808
11SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.18428429
12RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.82701692
13NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.78866665
14SPI1_23547873_ChIP-Seq_NB4_Human2.62884057
15SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.57136276
16IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.54534110
17STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.46920152
18STAT4_19710469_ChIP-ChIP_TH1__Mouse2.46535183
19MYB_21317192_ChIP-Seq_ERMYB_Mouse2.46415833
20MYC_22102868_ChIP-Seq_BL_Human2.37968310
21E2F7_22180533_ChIP-Seq_HELA_Human2.36244554
22VDR_21846776_ChIP-Seq_THP-1_Human2.33034161
23RUNX_20019798_ChIP-Seq_JUKART_Human2.32580972
24* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.32340723
25* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.31126157
26FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.27948580
27* MYB_26560356_Chip-Seq_TH2_Human2.20099560
28MEIS1_20887958_ChIP-Seq_HPC-7_Mouse2.19126013
29* RUNX1_22412390_ChIP-Seq_EML_Mouse2.17141804
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.10507881
31MAF_26560356_Chip-Seq_TH1_Human2.01766374
32MYB_26560356_Chip-Seq_TH1_Human2.00953833
33LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.98636117
34BRD4_27068464_Chip-Seq_AML-cells_Mouse1.93761849
35LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.93373558
36* VDR_24763502_ChIP-Seq_THP-1_Human1.92339751
37* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.90921947
38Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.89193649
39SPI1_23127762_ChIP-Seq_K562_Human1.85980047
40NOTCH1_21737748_ChIP-Seq_TLL_Human1.82840344
41* UTX_26944678_Chip-Seq_JUKART_Human1.80229409
42SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.73312210
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.68911058
44* TCF7_22412390_ChIP-Seq_EML_Mouse1.68545816
45GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.67335767
46CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.57906970
47PU_27001747_Chip-Seq_BMDM_Mouse1.53789963
48PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.53374936
49GATA1_22383799_ChIP-Seq_G1ME_Mouse1.50059138
50GATA3_27048872_Chip-Seq_THYMUS_Human1.48791409
51GATA2_22383799_ChIP-Seq_G1ME_Mouse1.48083974
52EGR1_19374776_ChIP-ChIP_THP-1_Human1.48029604
53SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.44078642
54FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.43419514
55CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.42209839
56ERG_20887958_ChIP-Seq_HPC-7_Mouse1.39178407
57SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.38647805
58GATA1_19941827_ChIP-Seq_MEL_Mouse1.37012885
59NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.34485739
60HOXB4_20404135_ChIP-ChIP_EML_Mouse1.34373570
61MAF_26560356_Chip-Seq_TH2_Human1.34205727
62PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.33076368
63STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.32883056
64GATA1_19941826_ChIP-Seq_K562_Human1.27877371
65GATA3_26560356_Chip-Seq_TH2_Human1.27838958
66CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.26737386
67GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.25215263
68BCOR_27268052_Chip-Seq_Bcells_Human1.21119252
69GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.19550410
70PU.1_20513432_ChIP-Seq_Bcells_Mouse1.19411183
71GATA1_22025678_ChIP-Seq_K562_Human1.19120629
72RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.18045609
73FOXM1_23109430_ChIP-Seq_U2OS_Human1.17239970
74PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.16485248
75* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.16084252
76NCOR1_26117541_ChIP-Seq_K562_Human1.14956426
77GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.14175865
78CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.13305187
79PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.11280073
80NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.03801956
81ELF1_20517297_ChIP-Seq_JURKAT_Human1.00661696
82KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.00621178
83VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.98434780
84VDR_24787735_ChIP-Seq_THP-1_Human0.98250025
85CTCF_21964334_ChIP-Seq_BJAB-B_Human0.98031957
86NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.97581349
87CIITA_25753668_ChIP-Seq_RAJI_Human0.96353283
88* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95886298
89ELF1_17652178_ChIP-ChIP_JURKAT_Human0.95227601
90LXR_22292898_ChIP-Seq_THP-1_Human0.94078410
91KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.93456047
92FOXP3_21729870_ChIP-Seq_TREG_Human0.91627973
93GATA2_21666600_ChIP-Seq_HMVEC_Human0.91517013
94CTCF_27219007_Chip-Seq_ERYTHROID_Human0.91339172
95BCL6_27268052_Chip-Seq_Bcells_Human0.89772302
96* ETS1_22383799_ChIP-Seq_G1ME_Mouse0.89289369
97STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.88783443
98CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.87973422
99CTCF_21964334_Chip-Seq_Bcells_Human0.86456358
100CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.85448099
101RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.84948265
102KDM2B_26808549_Chip-Seq_DND41_Human0.84243067
103THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.83654297
104ELK3_25401928_ChIP-Seq_HUVEC_Human0.83088196
105IKZF1_21737484_ChIP-ChIP_HCT116_Human0.82439549
106SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.76729914
107SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76531167
108KDM2B_26808549_Chip-Seq_SUP-B15_Human0.74714606
109SPI1_20517297_ChIP-Seq_HL60_Human0.74704089
110P300_27268052_Chip-Seq_Bcells_Human0.73228191
111FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.72885355
112FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.72381169
113CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.71562521
114VDR_23849224_ChIP-Seq_CD4+_Human0.70682970
115CTCF_26484167_Chip-Seq_Bcells_Mouse0.70567107
116TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.69339756
117GATA2_19941826_ChIP-Seq_K562_Human0.69035849
118EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.68236134

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation5.06386521
2MP0005671_abnormal_response_to3.56049971
3MP0005058_abnormal_lysosome_morphology3.07627595
4MP0001800_abnormal_humoral_immune3.01639618
5MP0006082_CNS_inflammation2.96452775
6MP0003436_decreased_susceptibility_to2.90884329
7MP0002452_abnormal_antigen_presenting2.80484094
8MP0000685_abnormal_immune_system2.74887004
9MP0005000_abnormal_immune_tolerance2.71796129
10MP0005387_immune_system_phenotype2.63677551
11MP0001790_abnormal_immune_system2.63677551
12MP0002723_abnormal_immune_serum2.63435096
13MP0005464_abnormal_platelet_physiology2.62153586
14MP0002148_abnormal_hypersensitivity_rea2.61448244
15MP0009785_altered_susceptibility_to2.54806793
16MP0002420_abnormal_adaptive_immunity2.54567928
17MP0001819_abnormal_immune_cell2.53570946
18MP0002419_abnormal_innate_immunity2.50937789
19MP0002132_abnormal_respiratory_system2.49532152
20MP0005025_abnormal_response_to2.45711853
21MP0003191_abnormal_cellular_cholesterol2.25572764
22MP0003011_delayed_dark_adaptation2.17784501
23MP0002398_abnormal_bone_marrow2.17571635
24MP0002396_abnormal_hematopoietic_system2.14501437
25MP0003763_abnormal_thymus_physiology2.14398206
26MP0003303_peritoneal_inflammation2.11097029
27MP0000689_abnormal_spleen_morphology2.08693595
28MP0003172_abnormal_lysosome_physiology2.08484273
29MP0000716_abnormal_immune_system2.04863829
30MP0002405_respiratory_system_inflammati1.92560080
31MP0009333_abnormal_splenocyte_physiolog1.91816133
32MP0005310_abnormal_salivary_gland1.91514713
33MP0003724_increased_susceptibility_to1.89460365
34MP0002722_abnormal_immune_system1.82868212
35MP0004808_abnormal_hematopoietic_stem1.75045009
36MP0002429_abnormal_blood_cell1.74837285
37MP0000465_gastrointestinal_hemorrhage1.72314411
38MP0005551_abnormal_eye_electrophysiolog1.69888815
39MP0001845_abnormal_inflammatory_respons1.67011029
40MP0004510_myositis1.65566815
41MP0001853_heart_inflammation1.62864084
42MP0003183_abnormal_peptide_metabolism1.59488766
43MP0003866_abnormal_defecation1.56342508
44MP0002166_altered_tumor_susceptibility1.54519823
45MP0009278_abnormal_bone_marrow1.53354571
46MP0001873_stomach_inflammation1.47951548
47MP0001545_abnormal_hematopoietic_system1.47356849
48MP0005397_hematopoietic_system_phenotyp1.47356849
49MP0010155_abnormal_intestine_physiology1.46153375
50MP0002138_abnormal_hepatobiliary_system1.44744638
51MP0008469_abnormal_protein_level1.41660905
52MP0001533_abnormal_skeleton_physiology1.35577641
53MP0003300_gastrointestinal_ulcer1.32935547
54MP0008260_abnormal_autophagy1.32572441
55MP0001986_abnormal_taste_sensitivity1.31401011
56MP0000703_abnormal_thymus_morphology1.31000465
57MP0008007_abnormal_cellular_replicative1.29078721
58MP0002933_joint_inflammation1.27034942
59MP0004381_abnormal_hair_follicle1.24699720
60MP0005174_abnormal_tail_pigmentation1.22307183
61MP0008004_abnormal_stomach_pH1.18103667
62MP0000490_abnormal_crypts_of1.18015436
63MP0004947_skin_inflammation1.16079887
64MP0000343_altered_response_to1.15794184
65MP0002006_tumorigenesis1.15119383
66MP0005253_abnormal_eye_physiology1.15071068
67MP0003045_fibrosis1.01395604
68MP0005410_abnormal_fertilization0.98880681
69MP0002998_abnormal_bone_remodeling0.96413557
70MP0005075_abnormal_melanosome_morpholog0.95744739
71MP0005166_decreased_susceptibility_to0.93707744
72MP0000858_altered_metastatic_potential0.93005896
73MP0003075_altered_response_to0.90708075
74MP0001663_abnormal_digestive_system0.90153715
75MP0010094_abnormal_chromosome_stability0.87434450
76MP0001919_abnormal_reproductive_system0.86360424
77MP0009764_decreased_sensitivity_to0.86045301
78MP0002136_abnormal_kidney_physiology0.85920208
79MP0001851_eye_inflammation0.84401622
80MP0002019_abnormal_tumor_incidence0.83631203
81MP0008058_abnormal_DNA_repair0.83575107
82MP0003786_premature_aging0.83410999
83MP0003448_altered_tumor_morphology0.81578645
84MP0006072_abnormal_retinal_apoptosis0.81060851
85MP0001324_abnormal_eye_pigmentation0.80690653
86MP0009840_abnormal_foam_cell0.80275538
87MP0001764_abnormal_homeostasis0.79481673
88MP0000015_abnormal_ear_pigmentation0.77946885
89MP0003077_abnormal_cell_cycle0.76470705
90MP0009763_increased_sensitivity_to0.76165376
91MP0003943_abnormal_hepatobiliary_system0.73382246
92MP0002928_abnormal_bile_duct0.72651706
93MP0002090_abnormal_vision0.72429647
94MP0008057_abnormal_DNA_replication0.72284846
95MP0000569_abnormal_digit_pigmentation0.70796832
96MP0010307_abnormal_tumor_latency0.70614359
97MP0005451_abnormal_body_composition0.70566151
98MP0004782_abnormal_surfactant_physiolog0.67743114
99MP0004147_increased_porphyrin_level0.67681361
100MP0001661_extended_life_span0.67505108
101MP0002009_preneoplasia0.66739106
102MP0002095_abnormal_skin_pigmentation0.65425840
103MP0003656_abnormal_erythrocyte_physiolo0.65392522
104MP0000371_diluted_coat_color0.64387204
105MP0004883_abnormal_blood_vessel0.62710432
106MP0008877_abnormal_DNA_methylation0.62365795
107MP0008995_early_reproductive_senescence0.61469707
108MP0003252_abnormal_bile_duct0.60686900
109MP0009765_abnormal_xenobiotic_induced0.60509879
110MP0000313_abnormal_cell_death0.60047931
111MP0003806_abnormal_nucleotide_metabolis0.60042280
112MP0003795_abnormal_bone_structure0.59632304
113MP0008873_increased_physiological_sensi0.58939794
114MP0006036_abnormal_mitochondrial_physio0.57948312
115MP0003690_abnormal_glial_cell0.57595381
116MP0009643_abnormal_urine_homeostasis0.57410364
117MP0009384_cardiac_valve_regurgitation0.57342629
118MP0000249_abnormal_blood_vessel0.57296792
119MP0003828_pulmonary_edema0.57253582
120MP0000609_abnormal_liver_physiology0.57252984
121MP0003638_abnormal_response/metabolism_0.56485985
122MP0001765_abnormal_ion_homeostasis0.55617742
123MP0009642_abnormal_blood_homeostasis0.54443159
124MP0003195_calcinosis0.54414167
125MP0005389_reproductive_system_phenotype0.54351346
126MP0002277_abnormal_respiratory_mucosa0.53670147
127MP0005083_abnormal_biliary_tract0.53067594

Predicted human phenotypes

RankGene SetZ-score
1Congenital stationary night blindness (HP:0007642)5.67835809
2Recurrent abscess formation (HP:0002722)5.19649840
3Recurrent bacterial skin infections (HP:0005406)4.85738426
4Systemic lupus erythematosus (HP:0002725)4.66440764
5Eczematoid dermatitis (HP:0000976)4.52768527
6Gonadal dysgenesis (HP:0000133)4.31809694
7Stomatitis (HP:0010280)4.28072381
8IgM deficiency (HP:0002850)4.09779488
9Bony spicule pigmentary retinopathy (HP:0007737)4.09575538
10Abnormal rod and cone electroretinograms (HP:0008323)3.89422608
11Increased neuronal autofluorescent lipopigment (HP:0002074)3.86452932
12Absent rod-and cone-mediated responses on ERG (HP:0007688)3.81887882
13Abnormality of glycolipid metabolism (HP:0010969)3.80697101
14Abnormality of liposaccharide metabolism (HP:0010968)3.80697101
15Abnormality of glycosphingolipid metabolism (HP:0004343)3.80697101
16Glomerulonephritis (HP:0000099)3.76912045
17Increased cerebral lipofuscin (HP:0011813)3.76897141
18T lymphocytopenia (HP:0005403)3.70653907
19Purpura (HP:0000979)3.58368096
20Testicular neoplasm (HP:0010788)3.53651376
21Abnormality of T cell number (HP:0011839)3.48731844
22Vacuolated lymphocytes (HP:0001922)3.46376943
23Colitis (HP:0002583)3.38275562
24Inflammation of the large intestine (HP:0002037)3.35709015
25Agammaglobulinemia (HP:0004432)3.35227087
26Myositis (HP:0100614)3.34100205
27Pigmentary retinal degeneration (HP:0001146)3.32624164
28Autoimmune hemolytic anemia (HP:0001890)3.31449451
29Gastrointestinal inflammation (HP:0004386)3.30413681
30Recurrent viral infections (HP:0004429)3.29171880
31Abnormal platelet volume (HP:0011876)3.27073798
32Gingival bleeding (HP:0000225)3.25124882
33Recurrent skin infections (HP:0001581)3.24427265
34Cellulitis (HP:0100658)3.17688516
35Recurrent fungal infections (HP:0002841)3.17472088
36Granulocytopenia (HP:0001913)3.14118793
37Increased IgM level (HP:0003496)3.13540337
38Abnormality of macrophages (HP:0004311)3.11501659
39Severe combined immunodeficiency (HP:0004430)3.08031809
40Chronic otitis media (HP:0000389)3.07431139
41Meningitis (HP:0001287)3.06272139
42Recurrent bronchitis (HP:0002837)3.04610276
43Thrombocytosis (HP:0001894)3.01137164
44Chronic diarrhea (HP:0002028)3.00269542
45Elevated erythrocyte sedimentation rate (HP:0003565)2.97458337
46Petechiae (HP:0000967)2.97108075
47Panhypogammaglobulinemia (HP:0003139)2.93299602
48Lymphopenia (HP:0001888)2.89731089
49Menorrhagia (HP:0000132)2.86936857
50Abnormality of B cell number (HP:0010975)2.85514432
51Gastrointestinal stroma tumor (HP:0100723)2.81914060
52Recurrent gram-negative bacterial infections (HP:0005420)2.81268602
53Increased IgE level (HP:0003212)2.80580854
54Mediastinal lymphadenopathy (HP:0100721)2.80491276
55Diaphragmatic weakness (HP:0009113)2.80053065
56Increased mean platelet volume (HP:0011877)2.78552563
57Attenuation of retinal blood vessels (HP:0007843)2.77739000
58Chronic obstructive pulmonary disease (HP:0006510)2.77689286
59Obstructive lung disease (HP:0006536)2.77689286
60Recurrent sinusitis (HP:0011108)2.77520439
61Dysostosis multiplex (HP:0000943)2.77110025
62Abnormality of cells of the lymphoid lineage (HP:0012140)2.76974417
63Eosinophilia (HP:0001880)2.76936905
64Mesangial abnormality (HP:0001966)2.76073528
65Vasculitis (HP:0002633)2.75759384
66Abnormal delayed hypersensitivity skin test (HP:0002963)2.74932663
67Male infertility (HP:0003251)2.72173893
68Agnosia (HP:0010524)2.71411108
69B lymphocytopenia (HP:0010976)2.71393019
70Anomalous pulmonary venous return (HP:0010772)2.71086536
71Combined immunodeficiency (HP:0005387)2.64125007
72Gastrointestinal infarctions (HP:0005244)2.60804827
73Leukocytosis (HP:0001974)2.60804386
74Dry hair (HP:0011359)2.60774455
75Abnormal platelet function (HP:0011869)2.60103255
76Impaired platelet aggregation (HP:0003540)2.60103255
77Pustule (HP:0200039)2.57324363
78Disinhibition (HP:0000734)2.56186992
79Pendular nystagmus (HP:0012043)2.54482728
80Autoimmune thrombocytopenia (HP:0001973)2.53796933
81Abnormality of male internal genitalia (HP:0000022)2.52929483
82Interstitial pulmonary disease (HP:0006530)2.51782655
83Chronic mucocutaneous candidiasis (HP:0002728)2.50153440
84Recurrent cutaneous fungal infections (HP:0011370)2.50153440
85Urticaria (HP:0001025)2.47523536
86Recurrent pneumonia (HP:0006532)2.47478968
87Hyperlipoproteinemia (HP:0010980)2.45897419
88Nasal polyposis (HP:0100582)2.45886628
89Abnormality of eosinophils (HP:0001879)2.45564775
90Papilloma (HP:0012740)2.42781675
91Verrucae (HP:0200043)2.42781675
92Abolished electroretinogram (ERG) (HP:0000550)2.41843063
93Prolonged bleeding time (HP:0003010)2.39484921
94Orchitis (HP:0100796)2.38299188
95Abnormality of the pulmonary veins (HP:0011718)2.35208476
96Axonal loss (HP:0003447)2.34278190
97Abnormality of T cell physiology (HP:0011840)2.33813700
98Abnormality of the prostate (HP:0008775)2.33514280
99Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.32536461
100Abnormality of the fingertips (HP:0001211)2.31522697
101Recurrent lower respiratory tract infections (HP:0002783)2.30254253
102Encephalitis (HP:0002383)2.29789015
103Pulmonary fibrosis (HP:0002206)2.29501207
104Progressive visual loss (HP:0000529)2.26285676
105Stridor (HP:0010307)2.26226055
106Fatigue (HP:0012378)2.25126790
107Emphysema (HP:0002097)2.24491121
108Chest pain (HP:0100749)2.24015684
109IgG deficiency (HP:0004315)2.23750982
110Osteomyelitis (HP:0002754)2.23655005
111Nephritis (HP:0000123)2.23613022
112Abnormality of the nasal mucosa (HP:0000433)2.23395269
113Epistaxis (HP:0000421)2.23200126
114Thyroiditis (HP:0100646)2.23192757
115Abnormality of T cells (HP:0002843)2.22896877
116Hypergammaglobulinemia (HP:0010702)2.21088607
117Joint swelling (HP:0001386)2.20994076
118Retrobulbar optic neuritis (HP:0100654)2.20697876
119Optic neuritis (HP:0100653)2.20697876
120Pulmonary infiltrates (HP:0002113)2.20496228
121Mucopolysacchariduria (HP:0008155)2.19750647
122Urinary glycosaminoglycan excretion (HP:0003541)2.19750647
123Hypochromic anemia (HP:0001931)2.17415840
124Papilledema (HP:0001085)2.17230934
125IgA deficiency (HP:0002720)2.16945194
126Abnormality of the peritoneum (HP:0002585)2.15860127
127Abnormality of mucopolysaccharide metabolism (HP:0011020)2.15732666
128Abnormality of polysaccharide metabolism (HP:0011012)2.15732666
129Abnormality of glycosaminoglycan metabolism (HP:0004371)2.15732666
130Chorioretinal atrophy (HP:0000533)2.15217858
131Sepsis (HP:0100806)2.12755256
132Lymphoma (HP:0002665)2.12608238
133Gingivitis (HP:0000230)2.12161328
134Spontaneous hematomas (HP:0007420)2.11248254
135Glomerulopathy (HP:0100820)2.09967377
136Complement deficiency (HP:0004431)2.08602701
137Skin rash (HP:0000988)2.07529215
138Macular degeneration (HP:0000608)2.06754453
139Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.06052828
140Retinal atrophy (HP:0001105)2.05889281
141Hepatosplenomegaly (HP:0001433)2.05524394
142Photophobia (HP:0000613)2.03069487
143Basal ganglia calcification (HP:0002135)2.02754734
144Acute hepatic failure (HP:0006554)2.02729895
145Abnormality of complement system (HP:0005339)2.02500558
146Hematochezia (HP:0002573)2.00604500
147Episodic fever (HP:0001954)1.98970759
148Abnormality of the heme biosynthetic pathway (HP:0010472)1.98563777
149Keratoconjunctivitis sicca (HP:0001097)1.95234957
150Hypoplasia of the thymus (HP:0000778)1.94166422

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.46982898
2TGFBR24.26366086
3KIT2.96660505
4TYK22.89990029
5CSF1R2.79410698
6TXK2.72589670
7PRPF4B2.63379370
8BLK2.57452039
9IRAK42.45873003
10ZAP702.41851140
11RIPK42.36709159
12TAOK32.29766893
13IKBKE2.28720251
14TBK12.28378508
15MAP3K142.16141543
16TESK22.04621084
17BTK2.00771068
18PKN21.90770798
19STK101.87284926
20JAK31.86672187
21SYK1.86550645
22MOS1.78748314
23TEC1.75301749
24IKBKB1.73783654
25GRK71.70757014
26EEF2K1.65170191
27MAP2K31.53357643
28LYN1.51229419
29RPS6KA41.48407189
30BMPR21.40551222
31FLT31.40342998
32JAK11.37568321
33GRK11.34166945
34TAOK21.32461662
35HCK1.29929385
36LCK1.27821514
37ITK1.27491321
38CLK11.26629131
39MAP3K61.23548364
40FES1.16534770
41KDR1.16199114
42NME21.14602174
43ERN11.14316010
44SIK21.14301619
45SCYL21.06012729
46IRAK31.05447028
47NEK91.01654692
48CSK1.00711088
49MAP3K131.00214425
50CDK190.99154341
51MAP3K110.98999376
52CHUK0.91752182
53PIM10.89156312
54PASK0.85368612
55MAP3K30.84416857
56PBK0.84402323
57KSR20.83435520
58MAP3K10.81399075
59MAP2K20.79518593
60PIK3CG0.77133761
61NLK0.75994439
62NEK20.75253655
63CDK30.73803338
64CDK40.73728032
65LRRK20.73132173
66MST40.72911449
67MATK0.72606010
68JAK20.72456196
69FGR0.72414909
70PDK10.70177912
71ACVR1B0.69745594
72TLK10.69148622
73BMX0.68289245
74FGFR30.68250847
75PDK20.67709505
76SIK30.65143748
77TGFBR10.63305950
78MAPK120.62702378
79PAK40.61909147
80MUSK0.61486827
81GRK60.60086886
82PTK2B0.59508435
83MAPK70.59204154
84STK40.58934341
85PDPK10.57606019
86CDK90.55463683
87RPS6KL10.55234732
88RPS6KC10.55234732
89CAMKK20.54703426
90CCNB10.54427740
91FYN0.53918617
92MARK30.52699060
93HIPK20.52325741
94TIE10.52034437
95CAMKK10.51102266
96SMG10.50743080
97RAF10.50601614
98MYLK0.49629664
99BCKDK0.49150507
100ADRBK20.49123440
101FGFR40.48569635
102ARAF0.45830035
103TAOK10.45412007
104PIM20.45383160
105MAP3K120.45220917
106NUAK10.44515991
107EIF2AK20.43310913
108PRKCQ0.43101054
109SIK10.42841947
110TNK20.42783879
111PRKCD0.38513404
112RPS6KA50.37862513
113MAP3K70.37659783
114TSSK60.37518068
115MAP3K50.37318097
116CDK80.36578682
117MAPKAPK30.36263462
118MAPKAPK20.35908499
119PRKD20.35787841
120ABL10.35600274
121MAPK150.33729020
122TNIK0.33617093
123IGF1R0.32994723
124RPS6KA60.32836844
125RPS6KB20.32726232
126YES10.32580779
127VRK10.32280636
128INSRR0.31452318
129MAPK110.31128600
130STK240.30415210
131ATR0.29213556
132BRAF0.29195382
133PRKCH0.27901378
134EPHB10.26961212
135MAPKAPK50.26897414
136MAPK30.26871799
137PINK10.26842666
138MARK20.26628878
139CAMK1D0.26481048
140MAP3K100.25745916
141MELK0.25570834
142EIF2AK30.25134414

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047444.88006235
2Primary immunodeficiency_Homo sapiens_hsa053403.25087936
3Other glycan degradation_Homo sapiens_hsa005113.20768820
4Glycosaminoglycan degradation_Homo sapiens_hsa005312.91169760
5Staphylococcus aureus infection_Homo sapiens_hsa051502.82223679
6B cell receptor signaling pathway_Homo sapiens_hsa046622.67282972
7Antigen processing and presentation_Homo sapiens_hsa046122.50333150
8Intestinal immune network for IgA production_Homo sapiens_hsa046722.50273481
9Leishmaniasis_Homo sapiens_hsa051402.48354120
10Type I diabetes mellitus_Homo sapiens_hsa049402.45937443
11Osteoclast differentiation_Homo sapiens_hsa043802.37216571
12Lysosome_Homo sapiens_hsa041422.20192250
13NF-kappa B signaling pathway_Homo sapiens_hsa040642.18874971
14Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.10617089
15Measles_Homo sapiens_hsa051621.93176231
16Toll-like receptor signaling pathway_Homo sapiens_hsa046201.85740260
17Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.80212679
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.72334786
19Hematopoietic cell lineage_Homo sapiens_hsa046401.72239384
20Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.64478166
21Herpes simplex infection_Homo sapiens_hsa051681.57823109
22RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.52271745
23Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.50274737
24Pertussis_Homo sapiens_hsa051331.49524043
25Base excision repair_Homo sapiens_hsa034101.47418704
26Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.44700995
27Tuberculosis_Homo sapiens_hsa051521.42717566
28DNA replication_Homo sapiens_hsa030301.37034170
29Jak-STAT signaling pathway_Homo sapiens_hsa046301.34665781
30Systemic lupus erythematosus_Homo sapiens_hsa053221.33989930
31Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.30912696
32Influenza A_Homo sapiens_hsa051641.30390235
33Allograft rejection_Homo sapiens_hsa053301.29709595
34Toxoplasmosis_Homo sapiens_hsa051451.25940643
35Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.19834047
36Homologous recombination_Homo sapiens_hsa034401.19296641
37Apoptosis_Homo sapiens_hsa042101.19067609
38NOD-like receptor signaling pathway_Homo sapiens_hsa046211.18719050
39T cell receptor signaling pathway_Homo sapiens_hsa046601.16877391
40Legionellosis_Homo sapiens_hsa051341.16798234
41Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.12591458
42Graft-versus-host disease_Homo sapiens_hsa053321.12350250
43Asthma_Homo sapiens_hsa053101.11997033
44Chemokine signaling pathway_Homo sapiens_hsa040621.11702764
45Shigellosis_Homo sapiens_hsa051311.07131213
46Platelet activation_Homo sapiens_hsa046111.04748850
47Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.96913483
48Hepatitis B_Homo sapiens_hsa051610.95989000
49Non-homologous end-joining_Homo sapiens_hsa034500.95476039
50Non-small cell lung cancer_Homo sapiens_hsa052230.94243315
51Malaria_Homo sapiens_hsa051440.93993467
52Transcriptional misregulation in cancer_Homo sapiens_hsa052020.89274500
53Leukocyte transendothelial migration_Homo sapiens_hsa046700.85923634
54Mismatch repair_Homo sapiens_hsa034300.85395709
55Salmonella infection_Homo sapiens_hsa051320.83069427
56Pancreatic cancer_Homo sapiens_hsa052120.81532600
57Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.73326795
58Rheumatoid arthritis_Homo sapiens_hsa053230.73177351
59Pentose and glucuronate interconversions_Homo sapiens_hsa000400.71787178
60TNF signaling pathway_Homo sapiens_hsa046680.70864969
61Ribosome_Homo sapiens_hsa030100.70653339
62Viral myocarditis_Homo sapiens_hsa054160.68013763
63Fatty acid elongation_Homo sapiens_hsa000620.67656364
64Fanconi anemia pathway_Homo sapiens_hsa034600.64665779
65Hepatitis C_Homo sapiens_hsa051600.64364551
66RNA degradation_Homo sapiens_hsa030180.63563011
67Chronic myeloid leukemia_Homo sapiens_hsa052200.61627262
68Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.60572278
69Vitamin digestion and absorption_Homo sapiens_hsa049770.60193279
70Autoimmune thyroid disease_Homo sapiens_hsa053200.58332895
71Acute myeloid leukemia_Homo sapiens_hsa052210.57290630
72Epstein-Barr virus infection_Homo sapiens_hsa051690.56525973
73African trypanosomiasis_Homo sapiens_hsa051430.55077438
74Phagosome_Homo sapiens_hsa041450.54671026
75Drug metabolism - other enzymes_Homo sapiens_hsa009830.54542180
76Glycerophospholipid metabolism_Homo sapiens_hsa005640.51651445
77Regulation of autophagy_Homo sapiens_hsa041400.49970748
78Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.49040728
79VEGF signaling pathway_Homo sapiens_hsa043700.48633724
80Nucleotide excision repair_Homo sapiens_hsa034200.48044248
81ABC transporters_Homo sapiens_hsa020100.47489648
82Pentose phosphate pathway_Homo sapiens_hsa000300.47201472
83HTLV-I infection_Homo sapiens_hsa051660.46759455
84Ether lipid metabolism_Homo sapiens_hsa005650.46665256
85Phosphatidylinositol signaling system_Homo sapiens_hsa040700.46470601
86Arachidonic acid metabolism_Homo sapiens_hsa005900.46258851
87Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.44858847
88Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.44639740
89N-Glycan biosynthesis_Homo sapiens_hsa005100.44606806
90Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.44434035
91AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.44415337
92Notch signaling pathway_Homo sapiens_hsa043300.42386930
93Inositol phosphate metabolism_Homo sapiens_hsa005620.41543368
94Pyrimidine metabolism_Homo sapiens_hsa002400.41245488
95p53 signaling pathway_Homo sapiens_hsa041150.40609184
96Cell cycle_Homo sapiens_hsa041100.38628703
97Endocytosis_Homo sapiens_hsa041440.38344940
98Complement and coagulation cascades_Homo sapiens_hsa046100.38192494
99Prolactin signaling pathway_Homo sapiens_hsa049170.35900640
100alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.35056869
101Sphingolipid metabolism_Homo sapiens_hsa006000.34519672
102SNARE interactions in vesicular transport_Homo sapiens_hsa041300.32935540
103Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.32839184
104Viral carcinogenesis_Homo sapiens_hsa052030.31688226
105Purine metabolism_Homo sapiens_hsa002300.31131011
106Renal cell carcinoma_Homo sapiens_hsa052110.29735148
107Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.29005445
108Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.28417584
109RNA polymerase_Homo sapiens_hsa030200.27724626
110Neurotrophin signaling pathway_Homo sapiens_hsa047220.27541339
111Alcoholism_Homo sapiens_hsa050340.27223113
112Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.26586761
113Thyroid cancer_Homo sapiens_hsa052160.26505477
114Linoleic acid metabolism_Homo sapiens_hsa005910.25708270
115mTOR signaling pathway_Homo sapiens_hsa041500.25248782
116Sphingolipid signaling pathway_Homo sapiens_hsa040710.25217460
117Basal transcription factors_Homo sapiens_hsa030220.24320408
118Choline metabolism in cancer_Homo sapiens_hsa052310.24319242
119Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.23843506
120Phospholipase D signaling pathway_Homo sapiens_hsa040720.23709384
121Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.23636817
122MAPK signaling pathway_Homo sapiens_hsa040100.22752811
123Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.22172591
124Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.21779297
125Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.18766435
126Ovarian steroidogenesis_Homo sapiens_hsa049130.18746982
127Colorectal cancer_Homo sapiens_hsa052100.18518863
128FoxO signaling pathway_Homo sapiens_hsa040680.18494239

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