SUV39H2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.17852693
2nuclear pore organization (GO:0006999)5.00982234
3mitotic metaphase plate congression (GO:0007080)4.67392010
4kinetochore organization (GO:0051383)4.60231696
5protein localization to kinetochore (GO:0034501)4.57571015
6mitotic chromosome condensation (GO:0007076)4.52568104
7DNA replication-dependent nucleosome organization (GO:0034723)4.51455363
8DNA replication-dependent nucleosome assembly (GO:0006335)4.51455363
9DNA double-strand break processing (GO:0000729)4.42516339
10DNA unwinding involved in DNA replication (GO:0006268)4.31321519
11DNA replication checkpoint (GO:0000076)4.31316241
12protein localization to chromosome, centromeric region (GO:0071459)4.31256004
13chromatin remodeling at centromere (GO:0031055)4.24934609
14DNA ligation (GO:0006266)4.24508660
15metaphase plate congression (GO:0051310)4.23887035
16mitotic sister chromatid cohesion (GO:0007064)4.22963598
17DNA replication initiation (GO:0006270)4.18652776
18mitotic nuclear envelope disassembly (GO:0007077)4.18196594
19CENP-A containing nucleosome assembly (GO:0034080)4.14246068
20mitotic sister chromatid segregation (GO:0000070)4.11123481
21kinetochore assembly (GO:0051382)4.09512443
22histone exchange (GO:0043486)4.06814061
23DNA strand elongation involved in DNA replication (GO:0006271)4.01349019
24DNA replication-independent nucleosome assembly (GO:0006336)4.01250596
25DNA replication-independent nucleosome organization (GO:0034724)4.01250596
26sister chromatid segregation (GO:0000819)3.95804326
27establishment of integrated proviral latency (GO:0075713)3.92688631
28protein K6-linked ubiquitination (GO:0085020)3.91337960
29membrane disassembly (GO:0030397)3.91333952
30nuclear envelope disassembly (GO:0051081)3.91333952
31pore complex assembly (GO:0046931)3.89778158
32attachment of spindle microtubules to kinetochore (GO:0008608)3.85660275
33regulation of centriole replication (GO:0046599)3.85527909
34DNA strand elongation (GO:0022616)3.81693875
35pre-miRNA processing (GO:0031054)3.80832084
36regulation of sister chromatid cohesion (GO:0007063)3.77973737
37regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.76111951
38regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.74783488
39regulation of mitotic spindle checkpoint (GO:1903504)3.74783488
40meiotic chromosome segregation (GO:0045132)3.73737609
41negative regulation of DNA-dependent DNA replication (GO:2000104)3.71686966
42positive regulation of chromosome segregation (GO:0051984)3.70594003
43DNA topological change (GO:0006265)3.70317135
44regulation of spindle organization (GO:0090224)3.68663498
45positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.68427731
46positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.68427731
47positive regulation of mitotic sister chromatid separation (GO:1901970)3.68427731
48establishment of chromosome localization (GO:0051303)3.67782135
49telomere maintenance via semi-conservative replication (GO:0032201)3.63331118
50regulation of chromosome segregation (GO:0051983)3.59020917
51telomere maintenance via recombination (GO:0000722)3.57997483
52replication fork processing (GO:0031297)3.57067139
53mitotic recombination (GO:0006312)3.55628691
54* chromatin assembly or disassembly (GO:0006333)3.53961000
55regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.53907945
56regulation of mitotic metaphase/anaphase transition (GO:0030071)3.52608773
57regulation of centrosome cycle (GO:0046605)3.51367341
58regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.50698698
59DNA catabolic process, exonucleolytic (GO:0000738)3.48610017
60spindle checkpoint (GO:0031577)3.47737388
61negative regulation of chromosome segregation (GO:0051985)3.46829268
62protein localization to chromosome (GO:0034502)3.45437538
63regulation of DNA endoreduplication (GO:0032875)3.44467690
64negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.43772261
65negative regulation of sister chromatid segregation (GO:0033046)3.43772261
66negative regulation of mitotic sister chromatid separation (GO:2000816)3.43772261
67negative regulation of mitotic sister chromatid segregation (GO:0033048)3.43772261
68negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.41560297
69double-strand break repair via nonhomologous end joining (GO:0006303)3.40598925
70non-recombinational repair (GO:0000726)3.40598925
71monoubiquitinated protein deubiquitination (GO:0035520)3.36025301
72regulation of histone H3-K9 methylation (GO:0051570)3.34812076
73regulation of mitotic sister chromatid separation (GO:0010965)3.33404778
74regulation of mitotic sister chromatid segregation (GO:0033047)3.33404778
75regulation of sister chromatid segregation (GO:0033045)3.33404778
76chromosome segregation (GO:0007059)3.33400822
77spindle assembly checkpoint (GO:0071173)3.32462426
78piRNA metabolic process (GO:0034587)3.32242449
79ATP-dependent chromatin remodeling (GO:0043044)3.31401820
80mitotic spindle checkpoint (GO:0071174)3.30044161
81mitotic spindle assembly checkpoint (GO:0007094)3.28904075
82regulation of mitotic spindle organization (GO:0060236)3.27496609
83DNA geometric change (GO:0032392)3.27369289
84synaptonemal complex assembly (GO:0007130)3.26956428
85DNA duplex unwinding (GO:0032508)3.26227774
86postreplication repair (GO:0006301)3.25486609
87negative regulation of histone methylation (GO:0031061)3.23332237
88ribosome assembly (GO:0042255)3.23305958
89regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.23270640
90heterochromatin organization (GO:0070828)3.23041715
91regulation of RNA export from nucleus (GO:0046831)3.20929623
92nucleotide-excision repair, DNA gap filling (GO:0006297)3.20245014
93proteasome assembly (GO:0043248)3.19683186
94centriole replication (GO:0007099)3.18435183
95chromosome condensation (GO:0030261)3.16935854
96nucleobase biosynthetic process (GO:0046112)3.12221298
97telomere maintenance via telomere lengthening (GO:0010833)3.11055383
98translesion synthesis (GO:0019985)3.10856078
99microtubule depolymerization (GO:0007019)3.10613371
100somatic diversification of immune receptors via somatic mutation (GO:0002566)3.10576040
101somatic hypermutation of immunoglobulin genes (GO:0016446)3.10576040
102regulation of centrosome duplication (GO:0010824)3.10186320
103resolution of meiotic recombination intermediates (GO:0000712)3.09340814
104recombinational repair (GO:0000725)3.06636567
105sister chromatid cohesion (GO:0007062)3.06569594
106folic acid-containing compound biosynthetic process (GO:0009396)3.06566331
107mitotic G2/M transition checkpoint (GO:0044818)3.05327816
108double-strand break repair via homologous recombination (GO:0000724)3.04209337
109chromatin assembly (GO:0031497)3.03734804
110regulation of double-strand break repair via homologous recombination (GO:0010569)3.02890540
111synapsis (GO:0007129)3.02872743
112regulation of helicase activity (GO:0051095)3.01121948
113DNA conformation change (GO:0071103)2.99353773
114gene silencing by RNA (GO:0031047)2.98781686
115nuclear envelope organization (GO:0006998)2.98710906
116maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.98405697
117telomere organization (GO:0032200)2.98219787
118telomere maintenance (GO:0000723)2.97749015
119purine nucleobase biosynthetic process (GO:0009113)2.97502466
120DNA packaging (GO:0006323)2.97379808
121negative regulation of mitosis (GO:0045839)2.96951283
122regulation of nuclear cell cycle DNA replication (GO:0033262)2.94183595
123anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.92740080
124chromosome organization involved in meiosis (GO:0070192)2.90536050
125maturation of 5.8S rRNA (GO:0000460)2.90204549
126DNA damage response, signal transduction resulting in transcription (GO:0042772)2.88613101
127IMP biosynthetic process (GO:0006188)2.87771832
128synaptonemal complex organization (GO:0070193)2.87171796

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.86336078
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.68990673
3* MYC_18555785_ChIP-Seq_MESCs_Mouse4.04956527
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.91205435
5MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.77414719
6MYC_19079543_ChIP-ChIP_MESCs_Mouse2.83275602
7AR_21909140_ChIP-Seq_LNCAP_Human2.74936512
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.65016349
9* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.63624887
10EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.60634179
11* E2F1_21310950_ChIP-Seq_MCF-7_Human2.46465439
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.29540120
13NELFA_20434984_ChIP-Seq_ESCs_Mouse2.29456877
14SALL1_21062744_ChIP-ChIP_HESCs_Human2.24972534
15EST1_17652178_ChIP-ChIP_JURKAT_Human2.24347511
16MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.17516550
17KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.17101546
18XRN2_22483619_ChIP-Seq_HELA_Human2.15354782
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.12577349
20MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.05840069
21MYCN_18555785_ChIP-Seq_MESCs_Mouse2.05716438
22CREB1_15753290_ChIP-ChIP_HEK293T_Human2.01185229
23* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.00902463
24E2F7_22180533_ChIP-Seq_HELA_Human10.8692368
25ETS1_20019798_ChIP-Seq_JURKAT_Human1.93886824
26GABP_17652178_ChIP-ChIP_JURKAT_Human1.87995297
27VDR_23849224_ChIP-Seq_CD4+_Human1.84414361
28HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.80811096
29EWS_26573619_Chip-Seq_HEK293_Human1.78085944
30PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.77714339
31POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.77268222
32TTF2_22483619_ChIP-Seq_HELA_Human1.71934139
33JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.70940029
34RBPJ_22232070_ChIP-Seq_NCS_Mouse1.69786721
35NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.64315964
36FOXP3_21729870_ChIP-Seq_TREG_Human1.64018873
37TP63_19390658_ChIP-ChIP_HaCaT_Human1.61940377
38* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.61477390
39MYC_22102868_ChIP-Seq_BL_Human1.61017317
40FUS_26573619_Chip-Seq_HEK293_Human1.58956439
41ZNF274_21170338_ChIP-Seq_K562_Hela1.57833223
42E2F1_18555785_ChIP-Seq_MESCs_Mouse1.57281387
43* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.56291483
44DCP1A_22483619_ChIP-Seq_HELA_Human1.55843227
45GABP_19822575_ChIP-Seq_HepG2_Human1.53847631
46KDM5A_27292631_Chip-Seq_BREAST_Human1.53783745
47NANOG_18555785_ChIP-Seq_MESCs_Mouse1.53302231
48* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.51272646
49POU5F1_16153702_ChIP-ChIP_HESCs_Human1.47322079
50SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.41372324
51E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.39562528
52IRF1_19129219_ChIP-ChIP_H3396_Human1.36203151
53* CIITA_25753668_ChIP-Seq_RAJI_Human1.31517441
54ELK1_19687146_ChIP-ChIP_HELA_Human1.30350080
55THAP11_20581084_ChIP-Seq_MESCs_Mouse1.30061420
56MYC_18940864_ChIP-ChIP_HL60_Human1.27473388
57HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.26624077
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.25707028
59FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.25087051
60ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.24887133
61* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.24446307
62KLF4_18555785_ChIP-Seq_MESCs_Mouse1.23718665
63IGF1R_20145208_ChIP-Seq_DFB_Human1.23146899
64SRF_21415370_ChIP-Seq_HL-1_Mouse1.22519159
65ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.22137100
66* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.21492228
67SOX2_18555785_ChIP-Seq_MESCs_Mouse1.20909117
68PADI4_21655091_ChIP-ChIP_MCF-7_Human1.18152097
69HOXB4_20404135_ChIP-ChIP_EML_Mouse1.16175817
70HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.15785769
71SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.15271554
72TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.13587165
73CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.13265953
74* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.12471268
75VDR_22108803_ChIP-Seq_LS180_Human1.11731802
76SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.10703672
77NANOG_21062744_ChIP-ChIP_HESCs_Human1.08635240
78ESR1_15608294_ChIP-ChIP_MCF-7_Human1.07604285
79CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.07520141
80HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.06148375
81PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.04814235
82TAF15_26573619_Chip-Seq_HEK293_Human0.98427045
83STAT3_1855785_ChIP-Seq_MESCs_Mouse0.97777643
84KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.95797744
85CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95539285
86FLI1_27457419_Chip-Seq_LIVER_Mouse0.93721379
87POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.91401682
88ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.90593080
89FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.87421716
90YY1_21170310_ChIP-Seq_MESCs_Mouse0.86014125
91* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.85215660
92SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.84846467
93P300_19829295_ChIP-Seq_ESCs_Human0.84489307
94TFEB_21752829_ChIP-Seq_HELA_Human0.84235130
95TCF3_18692474_ChIP-Seq_MESCs_Mouse0.84209768
96ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.84090546
97ERG_20887958_ChIP-Seq_HPC-7_Mouse0.83483738
98TCF3_18692474_ChIP-Seq_MEFs_Mouse0.82413394
99CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.81461524
100SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.78160341
101NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.78057987
102PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.77616932
103NOTCH1_21737748_ChIP-Seq_TLL_Human0.77179293
104ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.77106615
105SOX17_20123909_ChIP-Seq_XEN_Mouse0.77012073
106SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.76729210
107DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.75684152
108RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.74785784
109CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.74172953
110PKCTHETA_26484144_Chip-Seq_BREAST_Human0.73199036
111CHD1_26751641_Chip-Seq_LNCaP_Human0.72865986
112SOX2_16153702_ChIP-ChIP_HESCs_Human0.72290978
113HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.71054449
114TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.71017347
115ELF1_17652178_ChIP-ChIP_JURKAT_Human0.70665078
116EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.70652569
117MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.68113401
118GATA1_26923725_Chip-Seq_HPCs_Mouse0.67672434
119SOX9_26525672_Chip-Seq_HEART_Mouse0.67661494
120POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.67053654
121CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.67036871
122CTBP1_25329375_ChIP-Seq_LNCAP_Human0.65667586
123KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.64204537
124ZFP57_27257070_Chip-Seq_ESCs_Mouse0.63884389
125GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.63371739
126* FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.62750871
127CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.62733977
128CTBP2_25329375_ChIP-Seq_LNCAP_Human0.62227615
129NANOG_16153702_ChIP-ChIP_HESCs_Human0.61868206
130BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.61690650
131ELK1_22589737_ChIP-Seq_MCF10A_Human0.60104751

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.71655700
2MP0003693_abnormal_embryo_hatching4.60524262
3MP0003111_abnormal_nucleus_morphology4.25124928
4MP0004957_abnormal_blastocyst_morpholog3.97389844
5MP0003077_abnormal_cell_cycle3.89446675
6MP0008057_abnormal_DNA_replication3.88964211
7MP0008877_abnormal_DNA_methylation3.86676403
8MP0008058_abnormal_DNA_repair3.24757954
9MP0009697_abnormal_copulation2.63512754
10MP0003123_paternal_imprinting2.62994521
11MP0008007_abnormal_cellular_replicative2.62555912
12MP0008932_abnormal_embryonic_tissue2.47064114
13MP0002653_abnormal_ependyma_morphology2.35189708
14MP0001730_embryonic_growth_arrest2.31145477
15MP0000350_abnormal_cell_proliferation2.25399056
16MP0010307_abnormal_tumor_latency2.15476394
17MP0002210_abnormal_sex_determination2.03353135
18MP0003121_genomic_imprinting2.03135611
19MP0001929_abnormal_gametogenesis2.01129245
20MP0010352_gastrointestinal_tract_polyps1.89505256
21MP0003890_abnormal_embryonic-extraembry1.87535726
22MP0006292_abnormal_olfactory_placode1.86081477
23MP0001697_abnormal_embryo_size1.86008500
24MP0001672_abnormal_embryogenesis/_devel1.84968393
25MP0005380_embryogenesis_phenotype1.84968393
26MP0002085_abnormal_embryonic_tissue1.83343247
27MP0002084_abnormal_developmental_patter1.81361600
28MP0010030_abnormal_orbit_morphology1.79111487
29MP0003718_maternal_effect1.74935456
30MP0001145_abnormal_male_reproductive1.73522381
31MP0001529_abnormal_vocalization1.71077811
32MP0003941_abnormal_skin_development1.70143843
33MP0001293_anophthalmia1.66736921
34MP0003984_embryonic_growth_retardation1.63358678
35MP0000653_abnormal_sex_gland1.61523259
36MP0002396_abnormal_hematopoietic_system1.59975368
37MP0002088_abnormal_embryonic_growth/wei1.59273299
38MP0003786_premature_aging1.57030725
39MP0005076_abnormal_cell_differentiation1.53806134
40MP0003937_abnormal_limbs/digits/tail_de1.52561717
41MP0002080_prenatal_lethality1.50927806
42MP0003698_abnormal_male_reproductive1.48310568
43MP0004808_abnormal_hematopoietic_stem1.45561275
44MP0002086_abnormal_extraembryonic_tissu1.45462744
45MP0005410_abnormal_fertilization1.42603197
46MP0004197_abnormal_fetal_growth/weight/1.42165876
47MP0003787_abnormal_imprinting1.39250528
48MP0003315_abnormal_perineum_morphology1.38925136
49MP0000313_abnormal_cell_death1.32450741
50MP0003567_abnormal_fetal_cardiomyocyte1.31580443
51MP0006035_abnormal_mitochondrial_morpho1.29744978
52MP0009053_abnormal_anal_canal1.25236825
53MP0002234_abnormal_pharynx_morphology1.22720904
54MP0003136_yellow_coat_color1.21255869
55MP0000490_abnormal_crypts_of1.18739265
56MP0009672_abnormal_birth_weight1.16500777
57* MP0002019_abnormal_tumor_incidence1.15936424
58MP0000647_abnormal_sebaceous_gland1.09629225
59MP0001119_abnormal_female_reproductive1.09574974
60MP0002161_abnormal_fertility/fecundity1.08669139
61MP0001346_abnormal_lacrimal_gland1.07152555
62MP0003119_abnormal_digestive_system1.03156246
63MP0000631_abnormal_neuroendocrine_gland1.01064583
64MP0001915_intracranial_hemorrhage0.99285293
65MP0005253_abnormal_eye_physiology0.99114716
66MP0002160_abnormal_reproductive_system0.98648192
67MP0003705_abnormal_hypodermis_morpholog0.98587134
68MP0002102_abnormal_ear_morphology0.96364789
69MP0002751_abnormal_autonomic_nervous0.96359381
70MP0002092_abnormal_eye_morphology0.96285252
71MP0000537_abnormal_urethra_morphology0.95880705
72MP0000049_abnormal_middle_ear0.95667898
73MP0005397_hematopoietic_system_phenotyp0.94871987
74MP0001545_abnormal_hematopoietic_system0.94871987
75MP0009703_decreased_birth_body0.94739272
76MP0008995_early_reproductive_senescence0.94284305
77MP0003861_abnormal_nervous_system0.92864333
78MP0000432_abnormal_head_morphology0.89592153
79MP0003699_abnormal_female_reproductive0.88549399
80MP0000428_abnormal_craniofacial_morphol0.88420445
81MP0008789_abnormal_olfactory_epithelium0.86837634
82MP0001286_abnormal_eye_development0.86113305
83MP0003755_abnormal_palate_morphology0.85565969
84MP0001177_atelectasis0.85478382
85MP0002282_abnormal_trachea_morphology0.84983559
86MP0006072_abnormal_retinal_apoptosis0.84355943
87MP0003935_abnormal_craniofacial_develop0.82753610
88MP0000703_abnormal_thymus_morphology0.82318509
89MP0000778_abnormal_nervous_system0.81152889
90MP0000358_abnormal_cell_content/0.81015822
91MP0002090_abnormal_vision0.80449733
92MP0005389_reproductive_system_phenotype0.80405983
93MP0005187_abnormal_penis_morphology0.77240959
94MP0002697_abnormal_eye_size0.75920698
95MP0002111_abnormal_tail_morphology0.75705585
96MP0001849_ear_inflammation0.75448888
97MP0005623_abnormal_meninges_morphology0.72897478
98MP0002938_white_spotting0.71732031
99MP0000566_synostosis0.71712775
100MP0001188_hyperpigmentation0.71189841
101MP0002249_abnormal_larynx_morphology0.70895707
102MP0004233_abnormal_muscle_weight0.68774934
103MP0004264_abnormal_extraembryonic_tissu0.68233843
104MP0003221_abnormal_cardiomyocyte_apopto0.68223199
105MP0003943_abnormal_hepatobiliary_system0.67621543
106MP0005391_vision/eye_phenotype0.67360600
107MP0004133_heterotaxia0.66574184
108MP0002932_abnormal_joint_morphology0.65701446
109MP0000569_abnormal_digit_pigmentation0.65433708
110MP0002116_abnormal_craniofacial_bone0.65403785
111MP0000733_abnormal_muscle_development0.64996620
112MP0005395_other_phenotype0.64613259
113MP0002114_abnormal_axial_skeleton0.63683161
114MP0003880_abnormal_central_pattern0.63530048
115MP0005384_cellular_phenotype0.63288557
116MP0002163_abnormal_gland_morphology0.62955736
117MP0002233_abnormal_nose_morphology0.62752077
118MP0004147_increased_porphyrin_level0.62653936
119MP0006036_abnormal_mitochondrial_physio0.62612343
120MP0005621_abnormal_cell_physiology0.62611004
121MP0005499_abnormal_olfactory_system0.62523482
122MP0005394_taste/olfaction_phenotype0.62523482
123MP0005248_abnormal_Harderian_gland0.62461439
124MP0003763_abnormal_thymus_physiology0.62232236
125MP0003385_abnormal_body_wall0.61007200
126MP0002925_abnormal_cardiovascular_devel0.59831129
127MP0002081_perinatal_lethality0.59757548
128MP0003115_abnormal_respiratory_system0.58287338

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.27402802
2Chromsome breakage (HP:0040012)4.17663622
3Chromosomal breakage induced by crosslinking agents (HP:0003221)3.72024474
4Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.47202389
5Colon cancer (HP:0003003)3.47145091
6Medulloblastoma (HP:0002885)3.29362448
7Facial hemangioma (HP:0000329)3.25993481
8Abnormality of chromosome stability (HP:0003220)3.19328115
9Abnormality of the labia minora (HP:0012880)3.16424391
10Patellar aplasia (HP:0006443)3.09372563
11Breast hypoplasia (HP:0003187)3.06142118
12Selective tooth agenesis (HP:0001592)3.05238606
13Ectopic kidney (HP:0000086)3.04366139
14Rhabdomyosarcoma (HP:0002859)2.97676580
15Volvulus (HP:0002580)2.95754851
16Aplasia/Hypoplasia of the patella (HP:0006498)2.93132552
17Meckel diverticulum (HP:0002245)2.86702111
18Ependymoma (HP:0002888)2.86523651
19Reticulocytopenia (HP:0001896)2.83696005
20Aplasia/Hypoplasia of the uvula (HP:0010293)2.78782675
21Abnormality of the preputium (HP:0100587)2.74828905
22Supernumerary spleens (HP:0009799)2.74154560
23Abnormality of the ileum (HP:0001549)2.73497366
24Increased nuchal translucency (HP:0010880)2.68939707
25Short 4th metacarpal (HP:0010044)2.65806689
26Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.65806689
27Impulsivity (HP:0100710)2.64893687
28Nephroblastoma (Wilms tumor) (HP:0002667)2.61632812
29Clubbing of toes (HP:0100760)2.53693575
30Small intestinal stenosis (HP:0012848)2.52758356
31Duodenal stenosis (HP:0100867)2.52758356
32Aplasia/Hypoplasia of the sternum (HP:0006714)2.51355698
33Abnormal lung lobation (HP:0002101)2.51111335
34Sloping forehead (HP:0000340)2.49114308
35Oral leukoplakia (HP:0002745)2.42637123
36Embryonal renal neoplasm (HP:0011794)2.42220170
37Cortical dysplasia (HP:0002539)2.39900202
38Increased hepatocellular lipid droplets (HP:0006565)2.39181825
39Absent radius (HP:0003974)2.38980198
40Agnosia (HP:0010524)2.36588455
41Abnormality of abdominal situs (HP:0011620)2.35210128
42Abdominal situs inversus (HP:0003363)2.35210128
43Abnormal number of incisors (HP:0011064)2.34050473
44Myelodysplasia (HP:0002863)2.33138074
45Atresia of the external auditory canal (HP:0000413)2.32325184
46Neoplasm of striated muscle (HP:0009728)2.32111513
47Abnormal spermatogenesis (HP:0008669)2.30747016
48Carpal bone hypoplasia (HP:0001498)2.26134169
49Abnormality of the fingertips (HP:0001211)2.24214442
50Absent forearm bone (HP:0003953)2.22675267
51Aplasia involving forearm bones (HP:0009822)2.22675267
52Abnormal respiratory motile cilium physiology (HP:0012261)2.22223085
53Biliary tract neoplasm (HP:0100574)2.22053599
54Absent thumb (HP:0009777)2.20311443
55Papillary thyroid carcinoma (HP:0002895)2.19815446
56Lipid accumulation in hepatocytes (HP:0006561)2.19186990
57Neoplasm of the oral cavity (HP:0100649)2.16954242
58Overlapping toe (HP:0001845)2.16868246
59Microvesicular hepatic steatosis (HP:0001414)2.16719809
60Abnormality of the carotid arteries (HP:0005344)2.15799254
61Proximal placement of thumb (HP:0009623)2.15627155
62Abnormality of the astrocytes (HP:0100707)2.15606657
63Astrocytoma (HP:0009592)2.15606657
64Neoplasm of the pancreas (HP:0002894)2.14089033
65Pendular nystagmus (HP:0012043)2.12833396
66Intestinal atresia (HP:0011100)2.12711049
67Abnormality of the anterior horn cell (HP:0006802)2.10649893
68Degeneration of anterior horn cells (HP:0002398)2.10649893
69Hyperglycinemia (HP:0002154)2.09962873
70Deviation of the thumb (HP:0009603)2.09381715
71Acute encephalopathy (HP:0006846)2.09136577
72Abnormality of the duodenum (HP:0002246)2.08221441
73Septo-optic dysplasia (HP:0100842)2.07364956
74Prominent nose (HP:0000448)2.05612082
75Hypoplastic pelvis (HP:0008839)2.04970200
76Microglossia (HP:0000171)2.04209440
77Rib fusion (HP:0000902)2.04001298
78Male infertility (HP:0003251)2.01508375
79Short thumb (HP:0009778)2.00950755
80Basal cell carcinoma (HP:0002671)1.98852833
81Acute necrotizing encephalopathy (HP:0006965)1.98052202
82Cafe-au-lait spot (HP:0000957)1.97757426
83Oligodactyly (HP:0012165)1.97717716
84Glioma (HP:0009733)1.96880244
85Acute myeloid leukemia (HP:0004808)1.96770459
86Chronic bronchitis (HP:0004469)1.95326766
87Tracheoesophageal fistula (HP:0002575)1.95031666
88Sandal gap (HP:0001852)1.94596906
89Horseshoe kidney (HP:0000085)1.93467683
9011 pairs of ribs (HP:0000878)1.92681513
91Oligodactyly (hands) (HP:0001180)1.91967902
92Abnormality of the phalanges of the hallux (HP:0010057)1.90986488
93Choanal atresia (HP:0000453)1.89876187
94Pancreatic cysts (HP:0001737)1.88282477
95Triphalangeal thumb (HP:0001199)1.87905773
96Long eyelashes (HP:0000527)1.87656007
97Abnormal ciliary motility (HP:0012262)1.87435281
98Abnormality of the 4th metacarpal (HP:0010012)1.87199541
99Missing ribs (HP:0000921)1.86313328
100Facial cleft (HP:0002006)1.85524153
101Absent septum pellucidum (HP:0001331)1.85266904
102Preaxial hand polydactyly (HP:0001177)1.85136459
103Sparse lateral eyebrow (HP:0005338)1.84108728
104Tongue fasciculations (HP:0001308)1.83822631
105Capillary hemangiomas (HP:0005306)1.83419601
106Abnormality of the septum pellucidum (HP:0007375)1.83063150
107Neoplasm of the colon (HP:0100273)1.82108903
108Increased CSF lactate (HP:0002490)1.80580525
109Pancreatic fibrosis (HP:0100732)1.78659074
110Abnormality of the pons (HP:0007361)1.78403934
111Nephronophthisis (HP:0000090)1.78399148
112Dandy-Walker malformation (HP:0001305)1.77979804
113Abnormality of cells of the erythroid lineage (HP:0012130)1.77843936
114Shawl scrotum (HP:0000049)1.77636535
115Duplicated collecting system (HP:0000081)1.77390369
116Aplastic anemia (HP:0001915)1.76375471
117Arteriovenous malformation (HP:0100026)1.75548979
118Abnormality of midbrain morphology (HP:0002418)1.75430625
119Molar tooth sign on MRI (HP:0002419)1.75430625
120Abnormality of methionine metabolism (HP:0010901)1.74703423
121Gastrointestinal carcinoma (HP:0002672)1.74645904
122Malignant gastrointestinal tract tumors (HP:0006749)1.74645904
123Gastrointestinal atresia (HP:0002589)1.74040719
124Abnormality of serum amino acid levels (HP:0003112)1.73957647
125Esophageal atresia (HP:0002032)1.73427464
126Increased serum pyruvate (HP:0003542)1.73321893
127Hypoplasia of the pons (HP:0012110)1.72610397
128Aplasia/hypoplasia of the humerus (HP:0006507)1.72388688
129Embryonal neoplasm (HP:0002898)1.72382611
130High anterior hairline (HP:0009890)1.72293769
131Astigmatism (HP:0000483)1.72092450
132Megaloblastic anemia (HP:0001889)1.70787921
133Methylmalonic acidemia (HP:0002912)1.70488854
134Abnormal mitochondria in muscle tissue (HP:0008316)1.68099297
135Bifid tongue (HP:0010297)1.67238267
136Pancreatic islet-cell hyperplasia (HP:0004510)1.65479790
137Small hand (HP:0200055)1.65331252
138Breast carcinoma (HP:0003002)1.65247931
139Bone marrow hypocellularity (HP:0005528)1.61518095
140Median cleft lip (HP:0000161)1.60860641
141Increased serum lactate (HP:0002151)1.60122255
142Mitochondrial inheritance (HP:0001427)1.59747313
143Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.59455138
144Abnormality of alanine metabolism (HP:0010916)1.59455138
145Hyperalaninemia (HP:0003348)1.59455138
146Cerebral edema (HP:0002181)1.57897959
147Abnormality of cochlea (HP:0000375)1.56178211
148Aganglionic megacolon (HP:0002251)1.54380497
149Neoplasm of the adrenal cortex (HP:0100641)1.53890765
150Oligohydramnios (HP:0001562)1.53397734

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.48201844
2WEE14.05813318
3NEK23.35085316
4BUB13.31292852
5TTK3.06423297
6CDK123.05237490
7PLK42.72330375
8ACVR1B2.66924549
9VRK22.54121270
10SRPK12.52705337
11LATS12.44123657
12PLK12.16555648
13CHEK22.15739017
14BRSK22.00855498
15EIF2AK11.92170693
16MKNK11.89995871
17TAF11.89212968
18TRIM281.87496174
19NEK11.86025341
20ATR1.84198885
21STK38L1.80287602
22WNK31.78126908
23AURKB1.77446217
24TLK11.71453143
25DYRK31.68393982
26MKNK21.68002933
27CDK71.66838345
28CHEK11.64033772
29STK31.62690529
30RPS6KA41.60571883
31PLK31.55751578
32CCNB11.54912405
33CDK41.52995144
34ERBB31.52273112
35LATS21.51320311
36MAP3K101.45829133
37BMPR1B1.44194810
38BCR1.38966226
39EEF2K1.36407497
40VRK11.36264614
41PNCK1.35416958
42BRSK11.34805411
43STK101.32961329
44MAP3K81.32744649
45RPS6KB21.31864225
46ATM1.30418328
47MELK1.29094959
48MAP3K41.26550090
49AURKA1.22299875
50BRD41.22133291
51TSSK61.20919908
52TNIK1.15472213
53SCYL21.12739343
54MAP4K21.10321568
55CDK21.09208686
56CDK61.05588114
57PASK1.04266646
58MST41.03083244
59CSNK1G10.99984086
60STK40.98878707
61EIF2AK30.95392261
62MAP3K60.94602435
63CDK80.91204461
64CDK10.90369494
65BRAF0.88398670
66PDK40.88080982
67PDK30.88080982
68CSNK1G30.83220410
69CDK90.81809478
70CSNK1G20.73679758
71CSNK1A1L0.73381282
72MAP2K70.73147318
73PAK40.72559865
74NME10.72335392
75PRKD30.71116073
76ALK0.70976631
77TGFBR10.67993756
78PIM10.67281352
79CSNK2A20.62137532
80MTOR0.61117304
81TESK20.59667318
82STK160.58106422
83CDK190.54875066
84CSNK1E0.54676317
85PRKDC0.54343174
86DYRK20.49623304
87STK390.49383394
88RPS6KA50.49062916
89CSNK2A10.48720192
90PAK10.48599587
91ZAK0.45130524
92CSNK1D0.44610172
93RAF10.44504006
94MAPK140.44502684
95ERBB40.43311504
96PRKCI0.41145567
97MAPK130.35959150
98OXSR10.35596266
99GSK3B0.35567252
100KSR10.34067415
101AKT20.31838081
102AKT10.31440789
103PBK0.30271454
104CASK0.28633194
105CLK10.28093152
106NME20.28005956
107MAPK100.27241634
108CDK180.26523233
109CAMK1G0.26479154
110MARK30.26329179
111NEK90.25310106
112GRK10.25007506
113TAOK10.24954380
114TYRO30.24886840
115CDK140.24686317
116PKN20.24183196
117EIF2AK20.24062484
118FRK0.23487042
119FGFR10.23129280
120CDK150.22489343
121PLK20.22334847
122EPHA20.21921134
123MAPK10.21755189
124CDK11A0.21698817
125WNK40.20950350
126PDK20.20259379
127MAP3K50.20180696
128CDK30.20109096
129RPS6KA10.19255069
130STK240.18898646
131PAK20.18003556
132NUAK10.17921804

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.74113548
2Mismatch repair_Homo sapiens_hsa034304.23495789
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.71316955
4Cell cycle_Homo sapiens_hsa041103.57435749
5RNA transport_Homo sapiens_hsa030133.47195170
6Spliceosome_Homo sapiens_hsa030403.40595524
7Homologous recombination_Homo sapiens_hsa034403.39840123
8Base excision repair_Homo sapiens_hsa034102.87898330
9Nucleotide excision repair_Homo sapiens_hsa034202.84098256
10Fanconi anemia pathway_Homo sapiens_hsa034602.83651050
11Basal transcription factors_Homo sapiens_hsa030222.66017857
12RNA polymerase_Homo sapiens_hsa030202.47835506
13RNA degradation_Homo sapiens_hsa030182.37369477
14One carbon pool by folate_Homo sapiens_hsa006702.31521050
15Protein export_Homo sapiens_hsa030602.29688256
16mRNA surveillance pathway_Homo sapiens_hsa030152.27728603
17Ribosome_Homo sapiens_hsa030102.27306274
18Non-homologous end-joining_Homo sapiens_hsa034502.23480266
19Pyrimidine metabolism_Homo sapiens_hsa002401.94742792
20Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.83146653
21p53 signaling pathway_Homo sapiens_hsa041151.82794457
22Systemic lupus erythematosus_Homo sapiens_hsa053221.75300148
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.74642065
24Proteasome_Homo sapiens_hsa030501.70154793
25Oocyte meiosis_Homo sapiens_hsa041141.65630411
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.60967106
27Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.59179390
28Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.53087930
29Propanoate metabolism_Homo sapiens_hsa006401.52817145
30Steroid biosynthesis_Homo sapiens_hsa001001.31642682
31Oxidative phosphorylation_Homo sapiens_hsa001901.29535974
32Viral carcinogenesis_Homo sapiens_hsa052031.27581510
33Parkinsons disease_Homo sapiens_hsa050121.25739126
34MicroRNAs in cancer_Homo sapiens_hsa052061.17257742
35Epstein-Barr virus infection_Homo sapiens_hsa051691.16551992
36Purine metabolism_Homo sapiens_hsa002301.15253215
37Pyruvate metabolism_Homo sapiens_hsa006201.12911687
38Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.12612762
39Herpes simplex infection_Homo sapiens_hsa051681.12088612
40Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.10192346
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.01933749
42HTLV-I infection_Homo sapiens_hsa051660.99435140
43Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.96228063
44Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.94796732
45Thyroid cancer_Homo sapiens_hsa052160.88848435
46Basal cell carcinoma_Homo sapiens_hsa052170.88570848
47TGF-beta signaling pathway_Homo sapiens_hsa043500.87635916
48Hippo signaling pathway_Homo sapiens_hsa043900.86835567
49Small cell lung cancer_Homo sapiens_hsa052220.85484810
50Fatty acid elongation_Homo sapiens_hsa000620.85436920
512-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.84660869
52Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.83863848
53Pentose phosphate pathway_Homo sapiens_hsa000300.83373462
54Alcoholism_Homo sapiens_hsa050340.80242186
55Transcriptional misregulation in cancer_Homo sapiens_hsa052020.78648473
56Colorectal cancer_Homo sapiens_hsa052100.78163259
57Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.78015070
58Cysteine and methionine metabolism_Homo sapiens_hsa002700.73859712
59Adherens junction_Homo sapiens_hsa045200.70935433
60Antigen processing and presentation_Homo sapiens_hsa046120.70574141
61Hedgehog signaling pathway_Homo sapiens_hsa043400.66140320
62Butanoate metabolism_Homo sapiens_hsa006500.66115374
63* Lysine degradation_Homo sapiens_hsa003100.64447515
64Biosynthesis of amino acids_Homo sapiens_hsa012300.63781640
65Selenocompound metabolism_Homo sapiens_hsa004500.60990075
66Alzheimers disease_Homo sapiens_hsa050100.60862319
67Chronic myeloid leukemia_Homo sapiens_hsa052200.60760589
68Notch signaling pathway_Homo sapiens_hsa043300.58453237
69Phototransduction_Homo sapiens_hsa047440.56539482
70Sulfur relay system_Homo sapiens_hsa041220.54993601
71Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.51833739
72Hepatitis B_Homo sapiens_hsa051610.51422800
73Wnt signaling pathway_Homo sapiens_hsa043100.51091280
74Bladder cancer_Homo sapiens_hsa052190.50971323
75Metabolic pathways_Homo sapiens_hsa011000.50159450
76Pancreatic cancer_Homo sapiens_hsa052120.48776107
77Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.47293567
78Prostate cancer_Homo sapiens_hsa052150.47285262
79mTOR signaling pathway_Homo sapiens_hsa041500.45671411
80Pathways in cancer_Homo sapiens_hsa052000.45555554
81Glutathione metabolism_Homo sapiens_hsa004800.44784215
82Non-small cell lung cancer_Homo sapiens_hsa052230.42923309
83Renin-angiotensin system_Homo sapiens_hsa046140.40255936
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.39686753
85N-Glycan biosynthesis_Homo sapiens_hsa005100.38858909
86Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.37450720
87Vitamin B6 metabolism_Homo sapiens_hsa007500.37156844
88Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.35966371
89Central carbon metabolism in cancer_Homo sapiens_hsa052300.35732346
90Peroxisome_Homo sapiens_hsa041460.35367467
91FoxO signaling pathway_Homo sapiens_hsa040680.35113290
92Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.32464654
93Fatty acid metabolism_Homo sapiens_hsa012120.31368331
94Apoptosis_Homo sapiens_hsa042100.30885023
95Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.30644176
96Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.30381473
97Shigellosis_Homo sapiens_hsa051310.30213722
98Endometrial cancer_Homo sapiens_hsa052130.30195221
99Viral myocarditis_Homo sapiens_hsa054160.28244847
100Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.27796884
101Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.27386543
102HIF-1 signaling pathway_Homo sapiens_hsa040660.27096611
103Dorso-ventral axis formation_Homo sapiens_hsa043200.26956307
104Pentose and glucuronate interconversions_Homo sapiens_hsa000400.26717915
105Melanoma_Homo sapiens_hsa052180.26688332
106NOD-like receptor signaling pathway_Homo sapiens_hsa046210.26687397
107Tight junction_Homo sapiens_hsa045300.24457007
108Huntingtons disease_Homo sapiens_hsa050160.23951078
109Influenza A_Homo sapiens_hsa051640.22897162
110Vitamin digestion and absorption_Homo sapiens_hsa049770.21968997
111Caffeine metabolism_Homo sapiens_hsa002320.20311341
112Acute myeloid leukemia_Homo sapiens_hsa052210.19907721
113Cyanoamino acid metabolism_Homo sapiens_hsa004600.18994748
114NF-kappa B signaling pathway_Homo sapiens_hsa040640.18682925
115Proteoglycans in cancer_Homo sapiens_hsa052050.18379755
116Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.18055806
117Regulation of autophagy_Homo sapiens_hsa041400.18036734
118Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.17218124
119Renal cell carcinoma_Homo sapiens_hsa052110.16760720
120Arginine and proline metabolism_Homo sapiens_hsa003300.14867535
121Tryptophan metabolism_Homo sapiens_hsa003800.14729343
122Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.14465209
123Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.13903380
124Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.13469469
125Legionellosis_Homo sapiens_hsa051340.13110190
126Drug metabolism - other enzymes_Homo sapiens_hsa009830.12603151
127AMPK signaling pathway_Homo sapiens_hsa041520.12534224
128Glucagon signaling pathway_Homo sapiens_hsa049220.12476368
129Fatty acid degradation_Homo sapiens_hsa000710.11222489
130Folate biosynthesis_Homo sapiens_hsa007900.11182136
131Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.10992924
132Nicotine addiction_Homo sapiens_hsa050330.10773792
133Measles_Homo sapiens_hsa051620.10739143
134Cardiac muscle contraction_Homo sapiens_hsa042600.10348812
135Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.09294677
136beta-Alanine metabolism_Homo sapiens_hsa004100.09004652
137PI3K-Akt signaling pathway_Homo sapiens_hsa041510.08168102
138Nitrogen metabolism_Homo sapiens_hsa009100.08010186
139Glioma_Homo sapiens_hsa052140.07969725
140Ether lipid metabolism_Homo sapiens_hsa005650.07898589
141Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.07867085
142Carbon metabolism_Homo sapiens_hsa012000.07715188
143Longevity regulating pathway - mammal_Homo sapiens_hsa042110.07455833
144Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.07039559
145Neurotrophin signaling pathway_Homo sapiens_hsa047220.06296990

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