SYCN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1transcytosis (GO:0045056)8.61250181
2negative regulation of epidermis development (GO:0045683)8.32870890
3intestinal absorption (GO:0050892)8.05688973
4cobalamin metabolic process (GO:0009235)7.68327096
5sterol catabolic process (GO:0016127)7.60981770
6cholesterol catabolic process (GO:0006707)7.60981770
7peptidyl-proline hydroxylation (GO:0019511)7.21554570
8phosphatidylserine acyl-chain remodeling (GO:0036150)7.19749978
9phosphatidylglycerol acyl-chain remodeling (GO:0036148)7.05822183
10negative regulation of digestive system process (GO:0060457)6.67734259
11regulation of phospholipase A2 activity (GO:0032429)6.62211402
12glycolipid catabolic process (GO:0019377)6.55671628
13icosanoid transport (GO:0071715)6.36101965
14fatty acid derivative transport (GO:1901571)6.36101965
15membrane lipid catabolic process (GO:0046466)6.32842278
16cysteine metabolic process (GO:0006534)6.31967928
17regulation of keratinocyte differentiation (GO:0045616)6.10816277
18tetrapyrrole metabolic process (GO:0033013)6.08918505
19COPI coating of Golgi vesicle (GO:0048205)5.90079321
20Golgi transport vesicle coating (GO:0048200)5.90079321
21innate immune response in mucosa (GO:0002227)5.85190734
22regulation of keratinocyte proliferation (GO:0010837)5.66830892
23ceramide catabolic process (GO:0046514)5.63076081
24proline biosynthetic process (GO:0006561)5.56556004
25protein hydroxylation (GO:0018126)5.52624068
26branched-chain amino acid catabolic process (GO:0009083)5.50951645
27atrioventricular valve morphogenesis (GO:0003181)5.29467125
28valine metabolic process (GO:0006573)5.25350829
29phosphatidylethanolamine acyl-chain remodeling (GO:0036152)5.11665356
30activation of signaling protein activity involved in unfolded protein response (GO:0006987)4.94604472
31branched-chain amino acid metabolic process (GO:0009081)4.83006166
32intestinal epithelial cell development (GO:0060576)4.81079643
33daunorubicin metabolic process (GO:0044597)4.77172765
34polyketide metabolic process (GO:0030638)4.77172765
35doxorubicin metabolic process (GO:0044598)4.77172765
36mucosal immune response (GO:0002385)4.75091214
37protein maturation by protein folding (GO:0022417)4.75054486
38cellular modified amino acid catabolic process (GO:0042219)4.72782590
39positive regulation of nuclease activity (GO:0032075)4.72594829
40zinc ion transport (GO:0006829)4.60738423
41regulation of cholesterol homeostasis (GO:2000188)4.52652378
42response to endoplasmic reticulum stress (GO:0034976)4.51456077
43phosphatidylserine metabolic process (GO:0006658)4.51281232
44mitochondrial calcium ion transport (GO:0006851)4.50262990
45homocysteine metabolic process (GO:0050667)4.45858493
46endoplasmic reticulum unfolded protein response (GO:0030968)4.45206496
47water-soluble vitamin metabolic process (GO:0006767)4.40405141
48serine family amino acid biosynthetic process (GO:0009070)4.37752488
49leukotriene biosynthetic process (GO:0019370)4.35661196
50organ or tissue specific immune response (GO:0002251)4.33967257
51cellular response to unfolded protein (GO:0034620)4.32709036
52phosphatidylcholine acyl-chain remodeling (GO:0036151)4.31792500
53regulation of nuclease activity (GO:0032069)4.30083366
54aminoglycoside antibiotic metabolic process (GO:0030647)4.27856019
55GDP-mannose metabolic process (GO:0019673)4.24618961
56maintenance of protein localization in organelle (GO:0072595)4.20909632
57phospholipid catabolic process (GO:0009395)4.16394283
58positive regulation of heat generation (GO:0031652)4.15167128
59phosphatidic acid biosynthetic process (GO:0006654)4.14423838
60phosphatidic acid metabolic process (GO:0046473)4.14423838
61cellular response to topologically incorrect protein (GO:0035967)4.11809712
62signal peptide processing (GO:0006465)4.10655418
63ER-nucleus signaling pathway (GO:0006984)4.09702325
64negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)4.09057544
654-hydroxyproline metabolic process (GO:0019471)4.04849392
66defense response to Gram-positive bacterium (GO:0050830)4.04808656
67aspartate family amino acid catabolic process (GO:0009068)3.96584910
68regulation of fever generation (GO:0031620)3.95196037
69glutamine metabolic process (GO:0006541)3.94446480
70negative regulation of epithelial cell differentiation (GO:0030857)3.88465909
71steroid catabolic process (GO:0006706)3.84761070
72COPII vesicle coating (GO:0048208)3.83920236
73endocrine pancreas development (GO:0031018)3.83302930
74regulation of epidermal cell differentiation (GO:0045604)3.74305244
75negative regulation of epidermal cell differentiation (GO:0045605)3.74241025
76ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)3.73005308
77neutrophil mediated immunity (GO:0002446)3.71727721
78proline metabolic process (GO:0006560)3.70850548
79alditol phosphate metabolic process (GO:0052646)3.70109618
80leukotriene metabolic process (GO:0006691)3.64685429
81sphingolipid catabolic process (GO:0030149)3.64405763
82endothelial cell migration (GO:0043542)3.64060158
83creatine metabolic process (GO:0006600)3.62271670
84antibacterial humoral response (GO:0019731)3.59769815
85coenzyme catabolic process (GO:0009109)3.58788254
86regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.56187025
87response to unfolded protein (GO:0006986)3.56112133
88ER overload response (GO:0006983)3.53772626
89L-serine metabolic process (GO:0006563)3.53705285
90retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.49215852
91regulation of bile acid biosynthetic process (GO:0070857)3.48095372
92L-phenylalanine catabolic process (GO:0006559)3.45137281
93erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.45137281
94response to topologically incorrect protein (GO:0035966)3.43109098
95protein N-linked glycosylation via asparagine (GO:0018279)3.42246437
96serine family amino acid metabolic process (GO:0009069)3.41494275
97peptidyl-asparagine modification (GO:0018196)3.39961707
98vitamin metabolic process (GO:0006766)3.35882116
99antimicrobial humoral response (GO:0019730)3.35387271
100acute-phase response (GO:0006953)3.35129704
101phosphatidylglycerol metabolic process (GO:0046471)3.34070533
102erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.27411051
103L-phenylalanine metabolic process (GO:0006558)3.27411051
104icosanoid secretion (GO:0032309)3.15394755
105arachidonic acid secretion (GO:0050482)3.15394755
106cell redox homeostasis (GO:0045454)3.14844352
107mitochondrion distribution (GO:0048311)3.12360551
108protein N-linked glycosylation (GO:0006487)3.12039336
109regulation of heat generation (GO:0031650)3.11936765
110multicellular organismal catabolic process (GO:0044243)3.11659970
111glomerulus development (GO:0032835)3.10686645
112positive regulation of wound healing (GO:0090303)3.10310274
113sulfur amino acid biosynthetic process (GO:0000097)3.07691799
114cholesterol transport (GO:0030301)3.06850482
115sterol transport (GO:0015918)3.06850482
116biotin metabolic process (GO:0006768)3.05447468
117retinoid metabolic process (GO:0001523)3.05170674
118L-alpha-amino acid transmembrane transport (GO:1902475)3.03471618
119sulfur amino acid catabolic process (GO:0000098)3.01464733
120nucleotide-sugar biosynthetic process (GO:0009226)2.99724505
121digestive system process (GO:0022600)2.97282115
122UDP-N-acetylglucosamine metabolic process (GO:0006047)2.96584942
123regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (GO:1902175)2.94650781
124pancreas development (GO:0031016)2.92896829
125positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.88996089
126regulation of triglyceride catabolic process (GO:0010896)2.88244855
127phototransduction, visible light (GO:0007603)2.87514118
128diterpenoid metabolic process (GO:0016101)2.87045437
129multicellular organismal metabolic process (GO:0044236)2.86249705
130cholesterol metabolic process (GO:0008203)2.84768263
131endocardial cushion morphogenesis (GO:0003203)2.84521844
132polarized epithelial cell differentiation (GO:0030859)2.82689448
133myeloid leukocyte mediated immunity (GO:0002444)2.81338390
134phosphatidylinositol acyl-chain remodeling (GO:0036149)2.80842237
135alpha-amino acid biosynthetic process (GO:1901607)2.80780314
136glycine metabolic process (GO:0006544)2.80088287
137regulation of oxidative stress-induced cell death (GO:1903201)2.77518852
138cellular protein catabolic process (GO:0044257)2.77309372
139regulation of digestive system process (GO:0044058)2.77161034
140fatty acid derivative biosynthetic process (GO:1901570)2.77121677
141icosanoid biosynthetic process (GO:0046456)2.77121677
142extracellular matrix disassembly (GO:0022617)2.76156650
143glycine transport (GO:0015816)2.73990015
144long-chain fatty acid transport (GO:0015909)2.68377359
145epithelial cell migration (GO:0010631)2.65058040
146regulation of cardioblast differentiation (GO:0051890)2.56308937
147sterol metabolic process (GO:0016125)2.55434041
148epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.50721622
149terpenoid metabolic process (GO:0006721)2.49664111
150macroautophagy (GO:0016236)2.48916064
151defense response to Gram-negative bacterium (GO:0050829)2.46522540
152detection of visible light (GO:0009584)2.42634606
153S-adenosylmethionine metabolic process (GO:0046500)2.41686948
154positive regulation of calcium ion transport into cytosol (GO:0010524)2.40594001
155progesterone metabolic process (GO:0042448)2.37683170
156cellular response to follicle-stimulating hormone stimulus (GO:0071372)2.37473114
157embryonic foregut morphogenesis (GO:0048617)2.35433881
158negative regulation of receptor activity (GO:2000272)2.34702757
159regulation of epidermis development (GO:0045682)2.32927000
160intestinal cholesterol absorption (GO:0030299)18.0574965
161exocrine pancreas development (GO:0031017)16.3560456
162digestion (GO:0007586)13.9013425
163protein retention in ER lumen (GO:0006621)12.3391324
164maintenance of protein localization in endoplasmic reticulum (GO:0035437)11.5213053

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat8.49253291
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.28917002
3ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.05409419
4STAT6_21828071_ChIP-Seq_BEAS2B_Human3.63322220
5ERG_21242973_ChIP-ChIP_JURKAT_Human2.93714365
6IRF8_22096565_ChIP-ChIP_GC-B_Human2.89682573
7FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.88215721
8SOX2_27498859_Chip-Seq_STOMACH_Mouse2.68441873
9RXR_22158963_ChIP-Seq_LIVER_Mouse2.67152310
10* PPARA_22158963_ChIP-Seq_LIVER_Mouse2.55002773
11* GATA4_25053715_ChIP-Seq_YYC3_Human2.48831199
12ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.44205262
13LXR_22158963_ChIP-Seq_LIVER_Mouse2.24365140
14GATA6_25053715_ChIP-Seq_YYC3_Human2.23296749
15CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.22720863
16STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.17677994
17KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.14474483
18KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.14474483
19KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.14474483
20ESR1_21235772_ChIP-Seq_MCF-7_Human2.01838997
21ESR2_21235772_ChIP-Seq_MCF-7_Human1.99578541
22GATA1_22025678_ChIP-Seq_K562_Human1.90449806
23GATA1_26923725_Chip-Seq_HPCs_Mouse1.89033684
24PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.83406265
25TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.78634709
26NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.78216007
27CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.67961298
28PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.62211690
29HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.60889001
30E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.57436280
31TCF4_18268006_ChIP-ChIP_LS174T_Human1.53538750
32TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50926432
33PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.48269185
34FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.48255487
35ETV1_20927104_ChIP-Seq_GIST48_Human1.47789418
36SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.43657383
37HNFA_21074721_ChIP-Seq_CACO-2_Human1.43644299
38RARG_19884340_ChIP-ChIP_MEFs_Mouse1.41787692
39PHF8_20622853_ChIP-Seq_HELA_Human1.41291872
40PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.40868131
41CDX2_20551321_ChIP-Seq_CACO-2_Human1.40265279
42FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.39936938
43CREB1_26743006_Chip-Seq_LNCaP_Human1.37781844
44NFYA_21822215_ChIP-Seq_K562_Human1.37398649
45CHD1_26751641_Chip-Seq_LNCaP_Human1.36875092
46CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.35413046
47PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.34271789
48EGR1_19032775_ChIP-ChIP_M12_Human1.33186104
49GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.30899370
50CBX2_22325352_ChIP-Seq_293T-Rex_Human1.29631146
51SOX2_20726797_ChIP-Seq_SW620_Human1.29561750
52RBPJ_21746931_ChIP-Seq_IB4_Human1.29151915
53GATA6_21074721_ChIP-Seq_CACO-2_Human1.28783757
54NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.28347837
55SA1_27219007_Chip-Seq_ERYTHROID_Human1.27712423
56P63_26484246_Chip-Seq_KERATINOCYTES_Human1.27682589
57P68_20966046_ChIP-Seq_HELA_Human1.27632385
58ATF3_27146783_Chip-Seq_COLON_Human1.24015977
59CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.21457436
60SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.20893158
61PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.20745655
62SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.19523774
63LXR_22292898_ChIP-Seq_THP-1_Human1.17900618
64ZNF217_24962896_ChIP-Seq_MCF-7_Human1.17509481
65ESET_19884257_ChIP-Seq_ESCs_Mouse1.14825937
66BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.13810292
67NFYB_21822215_ChIP-Seq_K562_Human1.13016596
68JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.12585188
69TP63_22573176_ChIP-Seq_HFKS_Human1.11491620
70JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.10627639
71TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.10164309
72TAF2_19829295_ChIP-Seq_ESCs_Human1.07871029
73ERA_21632823_ChIP-Seq_H3396_Human1.07770135
74RUNX1_27514584_Chip-Seq_MCF-7_Human1.07509916
75FOXO3_23340844_ChIP-Seq_DLD1_Human1.07209225
76FOXH1_21741376_ChIP-Seq_ESCs_Human1.06558950
77FOXA1_25552417_ChIP-Seq_VCAP_Human1.06492518
78AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.05341853
79CLOCK_20551151_ChIP-Seq_293T_Human1.04145650
80AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.03422327
81SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.02715156
82SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02470142
83ERG_20517297_ChIP-Seq_VCAP_Human1.02352900
84TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.01991072
85TP63_17297297_ChIP-ChIP_HaCaT_Human1.01930185
86FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.01911658
87FOXA2_19822575_ChIP-Seq_HepG2_Human1.00503930
88ETS1_21867929_ChIP-Seq_TH2_Mouse1.00052896
89RACK7_27058665_Chip-Seq_MCF-7_Human0.99352817
90NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.97331667
91* FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.95714029
92IRF1_19129219_ChIP-ChIP_H3396_Human0.94915333
93OCT4_20526341_ChIP-Seq_ESCs_Human0.94745753
94P53_21459846_ChIP-Seq_SAOS-2_Human0.93806881
95ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93763161
96CTCF_20526341_ChIP-Seq_ESCs_Human0.93180266
97CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.92760418
98CDX2_19796622_ChIP-Seq_MESCs_Mouse0.92322799
99FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.92246839
100GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.91966284
101GATA3_24758297_ChIP-Seq_MCF-7_Human0.91675082
102BCOR_27268052_Chip-Seq_Bcells_Human0.91572134
103TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.90833140
104SA1_27219007_Chip-Seq_Bcells_Human0.90578214
105KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.89036439
106TBL1_22424771_ChIP-Seq_293T_Human0.87802837
107NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.87681176
108FOXP1_21924763_ChIP-Seq_HESCs_Human0.87117818
109ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.87111980
110GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.86898649
111DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.85589400
112SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.85142251
113RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.84920559
114CEBPB_22108803_ChIP-Seq_LS180_Human0.84870236
115KLF4_19829295_ChIP-Seq_ESCs_Human0.84255813
116CTCF_27219007_Chip-Seq_Bcells_Human0.83954235
117TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.82728012
118PPAR_26484153_Chip-Seq_NCI-H1993_Human0.81790209
119ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.81739371
120NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.81474063
121ELK4_26923725_Chip-Seq_MESODERM_Mouse0.80867379
122HTT_18923047_ChIP-ChIP_STHdh_Human0.79566343
123SALL4_18804426_ChIP-ChIP_XEN_Mouse0.79433240
124JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.79246604
125SOX3_22085726_ChIP-Seq_MUSCLE_Mouse0.78306219
126DNAJC2_21179169_ChIP-ChIP_NT2_Human0.77825652
127SOX2_21211035_ChIP-Seq_LN229_Human0.77734295
128CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77210166
129ZNF274_21170338_ChIP-Seq_K562_Hela0.76829931
130FOXM1_26456572_ChIP-Seq_MCF-7_Human0.76119968
131FLI1_21867929_ChIP-Seq_CD8_Mouse0.76108671
132PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.75015737
133SMAD4_21741376_ChIP-Seq_EPCs_Human0.72678929
134FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.72467519
135LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.71971580
136DPY_21335234_ChIP-Seq_ESCs_Mouse0.66523516
137PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.65291684
138SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.64839685
139CBP_21632823_ChIP-Seq_H3396_Human0.63924850
140CDX2_22108803_ChIP-Seq_LS180_Human0.61931767
141CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.61550580
142TP53_18474530_ChIP-ChIP_U2OS_Human0.59731336
143EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.59181849
144P300_19829295_ChIP-Seq_ESCs_Human0.58892232
145CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.58679201
146HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.56692717
147PIAS1_25552417_ChIP-Seq_VCAP_Human0.56488377
148CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.56269148
149TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.55812645
150PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.55773489
151HNF4A_19822575_ChIP-Seq_HepG2_Human0.55488857
152SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.54864909
153SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.54864909
154CJUN_26792858_Chip-Seq_BT549_Human0.54192893
155AR_20517297_ChIP-Seq_VCAP_Human0.52498595
156P53_22127205_ChIP-Seq_FIBROBLAST_Human0.52296045
157P300_27268052_Chip-Seq_Bcells_Human0.52181108
158CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.52042026

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005083_abnormal_biliary_tract9.33141209
2MP0001666_abnormal_nutrient_absorption9.22206663
3MP0005365_abnormal_bile_salt6.58398997
4MP0005220_abnormal_exocrine_pancreas6.48718355
5MP0003868_abnormal_feces_composition5.07643293
6MP0005084_abnormal_gallbladder_morpholo4.98814512
7MP0005085_abnormal_gallbladder_physiolo3.44535128
8MP0003959_abnormal_lean_body2.56853600
9MP0001664_abnormal_digestion2.54461464
10* MP0002693_abnormal_pancreas_physiology2.35785303
11MP0002138_abnormal_hepatobiliary_system2.32568676
12MP0002139_abnormal_hepatobiliary_system2.23473995
13MP0003705_abnormal_hypodermis_morpholog2.01970031
14MP0004264_abnormal_extraembryonic_tissu1.97021305
15MP0001944_abnormal_pancreas_morphology1.90854966
16MP0010234_abnormal_vibrissa_follicle1.70060793
17MP0005448_abnormal_energy_balance1.63860842
18MP0008995_early_reproductive_senescence1.47942135
19MP0004233_abnormal_muscle_weight1.46369096
20MP0003638_abnormal_response/metabolism_1.43457554
21MP0003252_abnormal_bile_duct1.42673186
22MP0002277_abnormal_respiratory_mucosa1.37019832
23MP0003828_pulmonary_edema1.35659486
24MP0002118_abnormal_lipid_homeostasis1.33664003
25MP0008004_abnormal_stomach_pH1.27486555
26MP0005165_increased_susceptibility_to1.27345760
27MP0005332_abnormal_amino_acid1.24232205
28MP0005451_abnormal_body_composition1.19892700
29MP0002928_abnormal_bile_duct1.18083394
30MP0001502_abnormal_circadian_rhythm1.10834934
31MP0003195_calcinosis1.08946414
32MP0002078_abnormal_glucose_homeostasis1.02467408
33MP0000470_abnormal_stomach_morphology1.02294240
34MP0003283_abnormal_digestive_organ1.02126369
35MP0001873_stomach_inflammation0.98179358
36MP0000003_abnormal_adipose_tissue0.96488513
37MP0000490_abnormal_crypts_of0.96215128
38MP0009643_abnormal_urine_homeostasis0.93603958
39MP0005408_hypopigmentation0.89590821
40MP0003123_paternal_imprinting0.84308068
41MP0001501_abnormal_sleep_pattern0.79994124
42MP0001663_abnormal_digestive_system0.79530836
43MP0009384_cardiac_valve_regurgitation0.78456071
44MP0002132_abnormal_respiratory_system0.77548456
45MP0003953_abnormal_hormone_level0.77027534
46MP0005535_abnormal_body_temperature0.77022171
47MP0003011_delayed_dark_adaptation0.76115571
48MP0005058_abnormal_lysosome_morphology0.75264191
49MP0003806_abnormal_nucleotide_metabolis0.73217733
50MP0006054_spinal_hemorrhage0.71091925
51MP0002970_abnormal_white_adipose0.70803527
52MP0003045_fibrosis0.70631806
53MP0003300_gastrointestinal_ulcer0.69615274
54MP0000613_abnormal_salivary_gland0.69586801
55MP0008789_abnormal_olfactory_epithelium0.69348111
56MP0008438_abnormal_cutaneous_collagen0.68842222
57MP0005381_digestive/alimentary_phenotyp0.67279280
58MP0008961_abnormal_basal_metabolism0.65213729
59MP0003186_abnormal_redox_activity0.58996795
60MP0005452_abnormal_adipose_tissue0.58933342
61MP0006036_abnormal_mitochondrial_physio0.58734890
62MP0010329_abnormal_lipoprotein_level0.58493333
63MP0001764_abnormal_homeostasis0.57130325
64MP0000598_abnormal_liver_morphology0.56766905
65MP0000609_abnormal_liver_physiology0.51894227
66MP0009765_abnormal_xenobiotic_induced0.51594062
67MP0003879_abnormal_hair_cell0.50602856
68MP0005499_abnormal_olfactory_system0.49833843
69MP0005394_taste/olfaction_phenotype0.49833843
70MP0002098_abnormal_vibrissa_morphology0.49623372
71MP0001731_abnormal_postnatal_growth0.47816261
72MP0009780_abnormal_chondrocyte_physiolo0.47234739
73MP0002796_impaired_skin_barrier0.47040431
74MP0004043_abnormal_pH_regulation0.46588799
75MP0005375_adipose_tissue_phenotype0.44489401
76MP0005360_urolithiasis0.44115783
77MP0002089_abnormal_postnatal_growth/wei0.43939222
78MP0005319_abnormal_enzyme/_coenzyme0.43439706
79MP0000750_abnormal_muscle_regeneration0.42661225
80MP0006138_congestive_heart_failure0.42125764
81MP0000858_altered_metastatic_potential0.41882997
82MP0002060_abnormal_skin_morphology0.41684423
83MP0002876_abnormal_thyroid_physiology0.40934646
84MP0005187_abnormal_penis_morphology0.39133285
85MP0002127_abnormal_cardiovascular_syste0.37748245
86MP0002163_abnormal_gland_morphology0.37518055
87MP0002160_abnormal_reproductive_system0.37127189
88MP0004185_abnormal_adipocyte_glucose0.37022298
89MP0008770_decreased_survivor_rate0.36476898
90MP0003795_abnormal_bone_structure0.35759539
91MP0010352_gastrointestinal_tract_polyps0.35606538
92MP0005636_abnormal_mineral_homeostasis0.35454023
93MP0000383_abnormal_hair_follicle0.34968467
94MP0000377_abnormal_hair_follicle0.34862527
95MP0002896_abnormal_bone_mineralization0.34663476
96MP0001765_abnormal_ion_homeostasis0.33531472
97MP0001756_abnormal_urination0.33233307
98MP0000367_abnormal_coat/_hair0.32284796
99MP0005334_abnormal_fat_pad0.32178017
100* MP0001845_abnormal_inflammatory_respons0.31980331
101MP0003221_abnormal_cardiomyocyte_apopto0.31222158
102MP0009642_abnormal_blood_homeostasis0.31151486
103MP0000639_abnormal_adrenal_gland0.30718887
104MP0000371_diluted_coat_color0.29332490
105MP0003329_amyloid_beta_deposits0.28715266
106MP0001542_abnormal_bone_strength0.28448302
107MP0002069_abnormal_eating/drinking_beha0.28284680
108MP0001661_extended_life_span0.28170392
109MP0003656_abnormal_erythrocyte_physiolo0.28122400
110MP0003183_abnormal_peptide_metabolism0.28116077
111MP0010678_abnormal_skin_adnexa0.27837912
112MP0003950_abnormal_plasma_membrane0.27679125
113MP0005646_abnormal_pituitary_gland0.27216338
114MP0000647_abnormal_sebaceous_gland0.27121239
115MP0008872_abnormal_physiological_respon0.27008362
116MP0005076_abnormal_cell_differentiation0.26150019
117MP0003943_abnormal_hepatobiliary_system0.26087534
118MP0002168_other_aberrant_phenotype0.26044614
119MP0001348_abnormal_lacrimal_gland0.25510626
120MP0003786_premature_aging0.24762596
121MP0005647_abnormal_sex_gland0.24684266
122MP0000462_abnormal_digestive_system0.24476926
123MP0009840_abnormal_foam_cell0.23672731
124MP0000432_abnormal_head_morphology0.23614183
125MP0010368_abnormal_lymphatic_system0.23337182
126MP0003567_abnormal_fetal_cardiomyocyte0.23244916
127MP0000013_abnormal_adipose_tissue0.23221523
128MP0008875_abnormal_xenobiotic_pharmacok0.22715904
129MP0009333_abnormal_splenocyte_physiolog0.22689000
130MP0000467_abnormal_esophagus_morphology0.22626126
131MP0001145_abnormal_male_reproductive0.22601327
132MP0010386_abnormal_urinary_bladder0.22251932
133MP0001784_abnormal_fluid_regulation0.21842132
134MP0009703_decreased_birth_body0.21078279
135MP0004924_abnormal_behavior0.20985226
136MP0003956_abnormal_body_size0.19594039
137MP0005410_abnormal_fertilization0.17555986
138MP0004019_abnormal_vitamin_homeostasis0.16398560
139MP0005388_respiratory_system_phenotype0.16274929
140MP0002133_abnormal_respiratory_system0.16274929
141MP0000538_abnormal_urinary_bladder0.16050458
142MP0005389_reproductive_system_phenotype0.16003871
143MP0002009_preneoplasia0.15492047
144MP0001851_eye_inflammation0.15227484

Predicted human phenotypes

RankGene SetZ-score
1Steatorrhea (HP:0002570)8.40505097
2Fat malabsorption (HP:0002630)7.00962244
3Gout (HP:0001997)6.74390145
4Short chin (HP:0000331)5.71045624
5Decreased subcutaneous fat (HP:0001002)5.60567711
6Exocrine pancreatic insufficiency (HP:0001738)5.16823950
7Abnormality of subcutaneous fat tissue (HP:0001001)5.07758934
8Type I diabetes mellitus (HP:0100651)4.94570142
9Abnormal pancreas size (HP:0012094)4.50525775
10Abnormality of the intrinsic pathway (HP:0010989)4.47112926
11Maternal diabetes (HP:0009800)4.43627555
12Male infertility (HP:0003251)4.24377153
13Hypoplasia of the pons (HP:0012110)4.19311828
14Sex reversal (HP:0012245)4.00427063
15Abnormal sex determination (HP:0012244)4.00427063
16Abnormality of the pons (HP:0007361)3.91623710
17Gonadal dysgenesis (HP:0000133)3.91161996
18Abnormality of aromatic amino acid family metabolism (HP:0004338)3.86171354
19Pancreatitis (HP:0001733)3.74967234
20Abnormality of the pleura (HP:0002103)3.67313840
21Premature skin wrinkling (HP:0100678)3.66588512
22Ketosis (HP:0001946)3.59668706
23Tubulointerstitial fibrosis (HP:0005576)3.56761732
24Ketoacidosis (HP:0001993)3.56595573
25Joint stiffness (HP:0001387)3.51320029
26Cortical dysplasia (HP:0002539)3.39516745
27Carpal bone hypoplasia (HP:0001498)3.33261992
28Tubulointerstitial nephritis (HP:0001970)3.32090733
29Abnormality of endocrine pancreas physiology (HP:0012093)3.29254478
30Abnormality of the pancreatic islet cells (HP:0006476)3.29254478
31Hypoglycemic coma (HP:0001325)3.28799266
32Tetraparesis (HP:0002273)3.27359994
33Hyperglycinemia (HP:0002154)3.21734074
34Hypoproteinemia (HP:0003075)3.18938279
35Anal atresia (HP:0002023)3.11108174
36Hyperuricemia (HP:0002149)3.10560151
37Increased purine levels (HP:0004368)3.10560151
38Abnormal tarsal ossification (HP:0008369)3.00906797
39Long foot (HP:0001833)2.94748327
40Abnormal ventriculo-arterial connection (HP:0011563)2.90822549
41Transposition of the great arteries (HP:0001669)2.90822549
42Abnormal connection of the cardiac segments (HP:0011545)2.90822549
43Hypoplastic left heart (HP:0004383)2.90651677
44Hypoglycemic seizures (HP:0002173)2.89557910
45Mesangial abnormality (HP:0001966)2.80103517
46Testicular neoplasm (HP:0010788)2.79946137
47Late onset (HP:0003584)2.77052450
48Hyperglycinuria (HP:0003108)2.76953311
49Abnormality of sulfur amino acid metabolism (HP:0004339)2.75846204
50Vascular calcification (HP:0004934)2.75826499
51Abnormality of the common coagulation pathway (HP:0010990)2.71271287
52Preauricular pit (HP:0004467)2.70049643
53Periauricular skin pits (HP:0100277)2.70049643
54Ventricular fibrillation (HP:0001663)2.68201461
55Abnormal protein glycosylation (HP:0012346)2.64166221
56Abnormal glycosylation (HP:0012345)2.64166221
57Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.64166221
58Abnormal protein N-linked glycosylation (HP:0012347)2.64166221
59Hyperinsulinemic hypoglycemia (HP:0000825)2.62391302
60Abnormality of serine family amino acid metabolism (HP:0010894)2.55455034
61Abnormality of glycine metabolism (HP:0010895)2.55455034
62Abnormality of the nasal septum (HP:0000419)2.52883885
63Prenatal maternal abnormality (HP:0002686)2.52696798
64Popliteal pterygium (HP:0009756)2.52229615
65Progressive muscle weakness (HP:0003323)2.49912880
66Optic nerve hypoplasia (HP:0000609)2.46196072
67Fatigue (HP:0012378)2.42069904
68Genetic anticipation (HP:0003743)2.41813612
69Cardiovascular calcification (HP:0011915)2.38387375
70Esophageal varix (HP:0002040)2.37761068
71Diaphragmatic weakness (HP:0009113)2.35625344
72Vacuolated lymphocytes (HP:0001922)2.30538028
73Pectus carinatum (HP:0000768)2.29432234
74Congenital glaucoma (HP:0001087)2.28553371
75Hypoplastic heart (HP:0001961)2.27607965
76Dysostosis multiplex (HP:0000943)2.26676185
77Right ventricular cardiomyopathy (HP:0011663)2.24885786
78Hypoplasia of the odontoid process (HP:0003311)2.24422222
79Skin pits (HP:0100276)2.23321468
80Acute hepatic failure (HP:0006554)2.22496413
81Small epiphyses (HP:0010585)2.17863174
82Hyperglycemia (HP:0003074)2.17444234
83Abnormal foot bone ossification (HP:0010675)2.14822467
84Hypoplasia of the uterus (HP:0000013)2.14240282
85Abnormality of the renal cortex (HP:0011035)2.13788655
86Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.13130296
87Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.11830247
88Urethral obstruction (HP:0000796)2.11587331
89Ileus (HP:0002595)2.08649041
90Symptomatic seizures (HP:0011145)2.07384371
91Flat acetabular roof (HP:0003180)2.06647060
92Abnormality of purine metabolism (HP:0004352)2.06576029
93Methylmalonic aciduria (HP:0012120)2.01967350
94Cortical visual impairment (HP:0100704)2.01831534
95Abnormality of methionine metabolism (HP:0010901)2.01626406
96Myocardial infarction (HP:0001658)1.99357828
97Reduced antithrombin III activity (HP:0001976)1.98610179
98Tubulointerstitial abnormality (HP:0001969)1.98386997
99Ankyloglossia (HP:0010296)1.97307152
100Flattened epiphyses (HP:0003071)1.97209419
101Barrel-shaped chest (HP:0001552)1.96781328
102Prolonged QT interval (HP:0001657)1.96273920
103Homocystinuria (HP:0002156)1.95836222
104Abnormality of homocysteine metabolism (HP:0010919)1.95836222
105Type II lissencephaly (HP:0007260)1.93638172
106Renal salt wasting (HP:0000127)1.92853252
107Conjugated hyperbilirubinemia (HP:0002908)1.91752355
108Tubular atrophy (HP:0000092)1.91354754
109Male pseudohermaphroditism (HP:0000037)1.90699150
110Type I transferrin isoform profile (HP:0003642)1.89905131
111Limb hypertonia (HP:0002509)1.89625810
112Beaking of vertebral bodies (HP:0004568)1.86983370
113Dicarboxylic aciduria (HP:0003215)1.86858841
114Abnormality of dicarboxylic acid metabolism (HP:0010995)1.86858841
115Hydroxyprolinuria (HP:0003080)1.84616145
116Abnormality of proline metabolism (HP:0010907)1.84616145
117Abnormal hemoglobin (HP:0011902)1.83651202
118Opisthotonus (HP:0002179)1.83477540
119Paraparesis (HP:0002385)1.81071547
120Absent eyebrow (HP:0002223)1.81045074
121Large for gestational age (HP:0001520)1.80154271
122Large hands (HP:0001176)1.80007729
123Abnormal biliary tract morphology (HP:0012440)1.78118933
124Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.77883089
125Abnormality of the odontoid process (HP:0003310)1.77573434
126Acute encephalopathy (HP:0006846)1.76724596
127Abnormality of aspartate family amino acid metabolism (HP:0010899)1.76134060
128Severe short stature (HP:0003510)1.75716643
129Abdominal distention (HP:0003270)1.74839769
130Facial shape deformation (HP:0011334)1.72584301
131Potter facies (HP:0002009)1.72584301
132Hyperammonemia (HP:0001987)1.72477300
133Hypsarrhythmia (HP:0002521)1.72453990
134Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.72416803
135Progressive sensorineural hearing impairment (HP:0000408)1.70578705
136Glossoptosis (HP:0000162)1.70170396
137Lower limb hyperreflexia (HP:0002395)1.68852095
138Portal hypertension (HP:0001409)1.68548118
139Abnormality of male internal genitalia (HP:0000022)1.68348601
140Enlarged kidneys (HP:0000105)1.67650734
141Absent eyelashes (HP:0000561)1.66938253
142Gowers sign (HP:0003391)1.64914317
143Germ cell neoplasia (HP:0100728)1.64866960
144Progressive cerebellar ataxia (HP:0002073)1.63743955
145Anal stenosis (HP:0002025)1.61739991
146Axonal loss (HP:0003447)1.61644710
147Congenital malformation of the right heart (HP:0011723)1.60595308
148Double outlet right ventricle (HP:0001719)1.60595308
149Chronic hepatic failure (HP:0100626)1.58980501
150Hypoplastic labia majora (HP:0000059)1.58286231
151Insulin-resistant diabetes mellitus (HP:0000831)1.57081022
152Abnormality of the hepatic vasculature (HP:0006707)1.51478483
153Abnormality of the distal phalanges of the toes (HP:0010182)1.50277042
154Primary adrenal insufficiency (HP:0008207)1.47009300
155Depressed nasal tip (HP:0000437)1.46691798
156Abnormality of the labia majora (HP:0012881)1.42502790
157Abnormality of urine glucose concentration (HP:0011016)1.42278652
158Glycosuria (HP:0003076)1.42278652
159Abdominal pain (HP:0002027)1.41672468
160Abnormality of the aortic arch (HP:0012303)1.40121691
161Papillary thyroid carcinoma (HP:0002895)1.38142102
162Cerebellar dysplasia (HP:0007033)1.37927059
163Vertebral compression fractures (HP:0002953)1.35120043
164Rectal prolapse (HP:0002035)1.34141161
165Abnormality of glutamine family amino acid metabolism (HP:0010902)1.29485286
166Aplasia/Hypoplasia of the scapulae (HP:0006713)1.28919205
167Hypoplastic scapulae (HP:0000882)1.28919205
168Cone-rod dystrophy (HP:0000548)1.28427476
169Infertility (HP:0000789)1.26718209
170Dry hair (HP:0011359)1.26076067

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK9.49463089
2ERN15.49748330
3EPHA25.27718829
4EIF2AK34.52759110
5MAP2K24.25949374
6TRIB33.07541602
7INSRR2.88901805
8PKN22.74471047
9FRK2.73800416
10MAPKAPK32.05941796
11IRAK31.93690624
12ZAP701.87894879
13TAOK31.83540052
14MAPK151.77765226
15NTRK31.76192085
16MAP2K11.73335846
17NME11.72109576
18GRK11.53398179
19SCYL21.53210708
20NME21.51939814
21PAK21.47214898
22WNK41.41070958
23SGK21.30736198
24SGK31.29146074
25PIK3CA1.22986510
26RPS6KB21.18428336
27NLK1.16358153
28PTK61.15228084
29PIK3CG1.13619378
30DYRK1A1.10991658
31FLT31.10711924
32CDK191.10195127
33PDGFRB1.05785129
34MAP3K21.03753997
35MST41.01991799
36EEF2K0.98130945
37SGK2230.90472292
38SGK4940.90472292
39PRKG20.89643000
40AKT30.89280280
41SIK10.88452856
42TAOK20.87979717
43CAMKK10.87540696
44TAOK10.87047186
45LATS10.86140417
46MST1R0.84893839
47PDK20.83751220
48OXSR10.77530415
49MAP2K60.76845382
50CAMKK20.75993967
51MAP3K50.72705935
52MAPK70.71492063
53IRAK20.71062537
54PRKCI0.70344645
55MELK0.70258839
56DYRK1B0.67004185
57MTOR0.65151012
58ERBB40.63994283
59DAPK20.63486015
60BMPR1B0.61672180
61ICK0.58858269
62BRSK20.58162152
63RIPK10.56072743
64RET0.55524581
65MARK20.55414005
66STK380.55410416
67MET0.54754511
68MAP3K10.54121137
69MUSK0.53522205
70CDK80.53415682
71PRKCE0.52686965
72PDPK10.52660591
73STK390.52380772
74KSR20.51745650
75CHUK0.51413479
76EPHB10.48461249
77IRAK40.48440396
78FER0.48224393
79PRKAA20.47878626
80LRRK20.47757089
81PRKCH0.47710497
82PRKCZ0.47329334
83RPS6KB10.47272010
84RPS6KA20.44895296
85NTRK10.40547460
86PDK10.38695836
87CAMK40.38379537
88CDK40.38280085
89FGFR40.37653829
90MAP3K90.37589201
91IRAK10.37200892
92PINK10.37194699
93PRKD30.36517880
94PTK20.36186148
95PAK30.35678196
96MAPK120.35628431
97MAP3K120.35534366
98NEK60.32526561
99EPHA30.32217236
100PIM10.31037776
101PDGFRA0.30855371
102MAPK30.30735119
103TRPM70.30019811
104ROCK10.29539657
105PDK30.29057081
106PDK40.29057081
107PRKACB0.28659001
108CSNK1G10.28441515
109SGK10.27435074
110MAP3K70.27362448
111IKBKE0.26759320
112JAK20.26521521
113LMTK20.26424675
114PRKACA0.25490744
115EIF2AK20.24840626
116RPS6KA10.24704375
117PASK0.24421003
118MAP3K30.23570019
119TSSK60.22952397
120DDR20.22935224
121ILK0.22814533
122TESK10.22721765
123HIPK20.21911503
124CDK120.21575674
125PRKD10.20697605
126IKBKB0.20300217
127ABL10.20089347
128ROCK20.19855033
129BRD40.19834036
130PRKACG0.18718179
131PIM20.18666403
132MAPK140.18183281
133MAP3K80.17987837
134BRAF0.17399012
135CAMK1D0.17263641
136DYRK20.17105682
137IGF1R0.17079162
138TBK10.16395221
139JAK10.16312539
140MAPK10.14393515
141CSNK1A10.12287778
142MAPK110.11562592
143PRKAA10.11166487
144CSNK1E0.11144827
145GSK3A0.10838947
146STK160.09808888
147MATK0.08638864
148EGFR0.08453760
149DAPK30.07755081
150EIF2AK10.07188669

Predicted pathways (KEGG)

RankGene SetZ-score
1Pancreatic secretion_Homo sapiens_hsa049728.37045555
2Fat digestion and absorption_Homo sapiens_hsa049755.95087785
3Protein digestion and absorption_Homo sapiens_hsa049745.54798128
4Maturity onset diabetes of the young_Homo sapiens_hsa049503.53462615
5Protein export_Homo sapiens_hsa030603.40266952
6Folate biosynthesis_Homo sapiens_hsa007902.94719298
7Glycerolipid metabolism_Homo sapiens_hsa005612.93411391
8Cyanoamino acid metabolism_Homo sapiens_hsa004602.52562537
9Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.38516125
10Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.24727437
11Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.13543142
12Vitamin digestion and absorption_Homo sapiens_hsa049771.94885415
13Steroid biosynthesis_Homo sapiens_hsa001001.81705848
14Propanoate metabolism_Homo sapiens_hsa006401.68540700
15Renin-angiotensin system_Homo sapiens_hsa046141.55695375
16Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.37521678
17alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.24402262
18Linoleic acid metabolism_Homo sapiens_hsa005911.20164450
19Sulfur metabolism_Homo sapiens_hsa009201.12048508
20Circadian rhythm_Homo sapiens_hsa047101.10593063
21Arginine and proline metabolism_Homo sapiens_hsa003301.08538183
22Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.04776260
23N-Glycan biosynthesis_Homo sapiens_hsa005100.98345267
242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.96828227
25Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.96611768
26Starch and sucrose metabolism_Homo sapiens_hsa005000.89598943
27Biosynthesis of amino acids_Homo sapiens_hsa012300.87351094
28Other glycan degradation_Homo sapiens_hsa005110.85125814
29Carbohydrate digestion and absorption_Homo sapiens_hsa049730.83205210
30Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.82691904
31Selenocompound metabolism_Homo sapiens_hsa004500.81823930
32Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.81339809
33Cysteine and methionine metabolism_Homo sapiens_hsa002700.79611774
34Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.73129207
35Insulin secretion_Homo sapiens_hsa049110.72683608
36Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.71616223
37Influenza A_Homo sapiens_hsa051640.70887296
38Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.70423424
39Vibrio cholerae infection_Homo sapiens_hsa051100.63662815
40Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.58482557
41Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.58171524
42Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.58066012
43One carbon pool by folate_Homo sapiens_hsa006700.57801690
44Notch signaling pathway_Homo sapiens_hsa043300.57053474
45Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.55771178
46Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.55394869
47Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.54094410
48beta-Alanine metabolism_Homo sapiens_hsa004100.52916221
49Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.49854597
50Primary bile acid biosynthesis_Homo sapiens_hsa001200.49422340
51Fructose and mannose metabolism_Homo sapiens_hsa000510.49364603
52Fatty acid degradation_Homo sapiens_hsa000710.47916549
53Pentose and glucuronate interconversions_Homo sapiens_hsa000400.47258693
54Pyruvate metabolism_Homo sapiens_hsa006200.43990998
55Vitamin B6 metabolism_Homo sapiens_hsa007500.43986310
56Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.42946027
57Arachidonic acid metabolism_Homo sapiens_hsa005900.42726577
58Sulfur relay system_Homo sapiens_hsa041220.42584495
59Glutathione metabolism_Homo sapiens_hsa004800.40566198
60Regulation of autophagy_Homo sapiens_hsa041400.40127225
61Tryptophan metabolism_Homo sapiens_hsa003800.37477554
62Legionellosis_Homo sapiens_hsa051340.36485066
63Steroid hormone biosynthesis_Homo sapiens_hsa001400.34363885
64Metabolic pathways_Homo sapiens_hsa011000.33840858
65Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.33744890
66Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.30621808
67Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.30332492
68Carbon metabolism_Homo sapiens_hsa012000.30326871
69Alzheimers disease_Homo sapiens_hsa050100.29958971
70Lysosome_Homo sapiens_hsa041420.29903688
71Ether lipid metabolism_Homo sapiens_hsa005650.29491799
72Parkinsons disease_Homo sapiens_hsa050120.27769529
73Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.27367295
74Arginine biosynthesis_Homo sapiens_hsa002200.27066522
75Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.25469431
76Vascular smooth muscle contraction_Homo sapiens_hsa042700.22681644
77Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.21410518
78Jak-STAT signaling pathway_Homo sapiens_hsa046300.18762442
79Endometrial cancer_Homo sapiens_hsa052130.17949780
80Glycerophospholipid metabolism_Homo sapiens_hsa005640.17840256
81Butanoate metabolism_Homo sapiens_hsa006500.16689070
82Hepatitis C_Homo sapiens_hsa051600.14091770
83VEGF signaling pathway_Homo sapiens_hsa043700.14016564
84Phototransduction_Homo sapiens_hsa047440.13795951
85SNARE interactions in vesicular transport_Homo sapiens_hsa041300.12805480
86Fatty acid metabolism_Homo sapiens_hsa012120.12110464
87Oxidative phosphorylation_Homo sapiens_hsa001900.11306055
88Nitrogen metabolism_Homo sapiens_hsa009100.10736753
89Bile secretion_Homo sapiens_hsa049760.10096107
90Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.08461669
91Galactose metabolism_Homo sapiens_hsa000520.08389804
92Calcium signaling pathway_Homo sapiens_hsa040200.08362976
93Insulin resistance_Homo sapiens_hsa049310.08140844
94Mineral absorption_Homo sapiens_hsa049780.07636987
95Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.07149472
96Adherens junction_Homo sapiens_hsa045200.06831318
97Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.06820259
98Histidine metabolism_Homo sapiens_hsa003400.06675465
99Retinol metabolism_Homo sapiens_hsa008300.06435082
100Chemical carcinogenesis_Homo sapiens_hsa052040.06419700
101Prostate cancer_Homo sapiens_hsa052150.05816359
102mTOR signaling pathway_Homo sapiens_hsa041500.05684955
103Complement and coagulation cascades_Homo sapiens_hsa046100.05503974
104Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.05008828
105Epstein-Barr virus infection_Homo sapiens_hsa051690.04887685
106Longevity regulating pathway - mammal_Homo sapiens_hsa042110.04383132
107Ribosome_Homo sapiens_hsa030100.04014944
108Peroxisome_Homo sapiens_hsa041460.03271189
109Thyroid hormone synthesis_Homo sapiens_hsa049180.02772558
110Ras signaling pathway_Homo sapiens_hsa040140.01822329
111Viral carcinogenesis_Homo sapiens_hsa052030.01772649
112Cocaine addiction_Homo sapiens_hsa050300.01554285
113TGF-beta signaling pathway_Homo sapiens_hsa043500.00551168
114Sphingolipid metabolism_Homo sapiens_hsa006000.00547592
115Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960-0.1372641
116Estrogen signaling pathway_Homo sapiens_hsa04915-0.1328713
117MAPK signaling pathway_Homo sapiens_hsa04010-0.1282437
118Inositol phosphate metabolism_Homo sapiens_hsa00562-0.1138507
119Thyroid hormone signaling pathway_Homo sapiens_hsa04919-0.1129340
120Thyroid cancer_Homo sapiens_hsa05216-0.1050190
121Hippo signaling pathway_Homo sapiens_hsa04390-0.1044655
122Aldosterone synthesis and secretion_Homo sapiens_hsa04925-0.0906270
123TNF signaling pathway_Homo sapiens_hsa04668-0.0731538
124Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0573522
125ErbB signaling pathway_Homo sapiens_hsa04012-0.0539156
126Lysine degradation_Homo sapiens_hsa00310-0.0500013
127Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040-0.0495156
128Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760-0.0378424
129FoxO signaling pathway_Homo sapiens_hsa04068-0.0285946
130ABC transporters_Homo sapiens_hsa02010-0.0265331
131Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.0205901
132Tight junction_Homo sapiens_hsa04530-0.0139971
133Type I diabetes mellitus_Homo sapiens_hsa04940-0.0095531
134Bladder cancer_Homo sapiens_hsa05219-0.0018478
135Toxoplasmosis_Homo sapiens_hsa05145-0.0002715

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