SYCP2L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1piRNA metabolic process (GO:0034587)7.30849226
2regulation of female gonad development (GO:2000194)6.82725856
3mitotic metaphase plate congression (GO:0007080)6.66283947
4attachment of spindle microtubules to kinetochore (GO:0008608)6.55113803
5nuclear pore organization (GO:0006999)6.54393712
6meiotic cell cycle (GO:0051321)5.93932240
7female gamete generation (GO:0007292)5.71175723
8metaphase plate congression (GO:0051310)5.65718085
9mitotic chromosome condensation (GO:0007076)5.56676912
10DNA methylation involved in gamete generation (GO:0043046)5.42447509
11protein localization to kinetochore (GO:0034501)5.17929108
12establishment of chromosome localization (GO:0051303)5.16724393
13negative regulation of retinoic acid receptor signaling pathway (GO:0048387)5.15494044
14regulation of meiosis (GO:0040020)4.95590711
15regulation of sister chromatid cohesion (GO:0007063)4.87877095
16histone H2A monoubiquitination (GO:0035518)4.87743236
17male meiosis (GO:0007140)4.85550542
18protein localization to chromosome, centromeric region (GO:0071459)4.81858998
19regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.80872358
20meiotic chromosome segregation (GO:0045132)4.74591037
21centriole replication (GO:0007099)4.71527167
22mitotic sister chromatid segregation (GO:0000070)4.68152065
23negative regulation of meiosis (GO:0045835)4.66871451
24notochord development (GO:0030903)4.58123217
25positive regulation of chromosome segregation (GO:0051984)4.48737524
26nuclear pore complex assembly (GO:0051292)4.42820669
27oocyte maturation (GO:0001556)4.41203838
28maturation of 5.8S rRNA (GO:0000460)4.40590944
29centriole assembly (GO:0098534)4.38038984
30regulation of exit from mitosis (GO:0007096)4.35094065
31kinetochore assembly (GO:0051382)4.28213087
32positive regulation of mitotic sister chromatid separation (GO:1901970)4.20416273
33positive regulation of mitotic metaphase/anaphase transition (GO:0045842)4.20416273
34positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)4.20416273
35kinetochore organization (GO:0051383)4.18446466
36synapsis (GO:0007129)4.17807343
37DNA damage induced protein phosphorylation (GO:0006975)4.17050761
38regulation of spindle organization (GO:0090224)4.16346293
39regulation of DNA methylation (GO:0044030)4.15271522
40positive regulation of histone H3-K4 methylation (GO:0051571)4.13559259
41chromosome segregation (GO:0007059)4.12718715
42regulation of meiosis I (GO:0060631)4.12396180
43protein localization to chromosome (GO:0034502)4.12333624
44regulation of mitotic spindle organization (GO:0060236)4.11951057
45regulation of transforming growth factor beta2 production (GO:0032909)4.10305115
46multicellular organism reproduction (GO:0032504)4.07671835
47regulation of acrosome reaction (GO:0060046)4.04573918
48regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.03945535
49mitotic nuclear envelope disassembly (GO:0007077)4.03862693
50CENP-A containing nucleosome assembly (GO:0034080)4.00452716
51glycerophospholipid catabolic process (GO:0046475)4.00104041
52regulation of histone H3-K9 methylation (GO:0051570)3.99583061
53regulation of retinoic acid receptor signaling pathway (GO:0048385)3.98300662
54regulation of meiotic cell cycle (GO:0051445)3.97308204
55histone H2A ubiquitination (GO:0033522)3.95507592
56DNA alkylation (GO:0006305)3.94769718
57DNA methylation (GO:0006306)3.94769718
58DNA topological change (GO:0006265)3.92884826
59female gonad development (GO:0008585)3.91525560
60negative regulation of hormone biosynthetic process (GO:0032353)3.89908420
61negative regulation of hormone metabolic process (GO:0032351)3.89908420
62spindle checkpoint (GO:0031577)3.89883350
63resolution of meiotic recombination intermediates (GO:0000712)3.83861948
64sister chromatid segregation (GO:0000819)3.83739414
65chromatin remodeling at centromere (GO:0031055)3.83653800
66membrane disassembly (GO:0030397)3.80664603
67nuclear envelope disassembly (GO:0051081)3.80664603
68monoubiquitinated protein deubiquitination (GO:0035520)3.80403073
69protein K6-linked ubiquitination (GO:0085020)3.80053602
70DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla3.76499968
71histone exchange (GO:0043486)3.75055390
72oogenesis (GO:0048477)3.72855745
73telomere maintenance via semi-conservative replication (GO:0032201)3.72117644
74mitotic sister chromatid cohesion (GO:0007064)3.68413370
75microtubule cytoskeleton organization involved in mitosis (GO:1902850)3.67450735
76DNA replication-independent nucleosome assembly (GO:0006336)3.64554573
77DNA replication-independent nucleosome organization (GO:0034724)3.64554573
78regulation of chromosome segregation (GO:0051983)3.64113404
79DNA damage response, signal transduction resulting in transcription (GO:0042772)3.60502024
80regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.56899081
81DNA strand elongation involved in DNA replication (GO:0006271)3.56761991
82nucleotide-excision repair, DNA gap filling (GO:0006297)3.56611942
83translesion synthesis (GO:0019985)3.51321878
84regulation of histone H3-K27 methylation (GO:0061085)3.49655645
85negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.47721210
86pore complex assembly (GO:0046931)3.47482799
87mitotic spindle checkpoint (GO:0071174)3.47439077
88gene silencing by RNA (GO:0031047)3.46150722
89DNA replication checkpoint (GO:0000076)3.45142590
90negative regulation of nuclear division (GO:0051784)3.44710344
91negative regulation of cell division (GO:0051782)3.44296010
92regulation of histone H3-K4 methylation (GO:0051569)3.43275566
93microtubule depolymerization (GO:0007019)3.42637075
94DNA strand elongation (GO:0022616)3.42408019
95negative regulation of histone methylation (GO:0031061)3.42353130
96negative regulation of DNA-templated transcription, elongation (GO:0032785)3.41726122
97negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.41726122
98DNA double-strand break processing (GO:0000729)3.39213906
99mitotic recombination (GO:0006312)3.38492896
100regulation of mitotic metaphase/anaphase transition (GO:0030071)3.38329124
101telomere maintenance via recombination (GO:0000722)3.37270987
102regulation of hypersensitivity (GO:0002883)3.36535140
103replication fork processing (GO:0031297)3.32430226
104negative regulation of meiotic cell cycle (GO:0051447)3.31566711
105regulation of double-strand break repair via homologous recombination (GO:0010569)3.28556253
106mitotic G2/M transition checkpoint (GO:0044818)3.27911200
107negative regulation of DNA-dependent DNA replication (GO:2000104)3.26831412
108postreplication repair (GO:0006301)3.26078808
109negative regulation of chromosome segregation (GO:0051985)3.25664329
110DNA replication initiation (GO:0006270)3.25458628
111microtubule anchoring (GO:0034453)3.24627945
112regulation of mitotic sister chromatid segregation (GO:0033047)3.24440883
113regulation of sister chromatid segregation (GO:0033045)3.24440883
114regulation of mitotic sister chromatid separation (GO:0010965)3.24440883
115negative regulation of mitotic sister chromatid separation (GO:2000816)3.23245876
116negative regulation of mitotic sister chromatid segregation (GO:0033048)3.23245876
117negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.23245876
118negative regulation of sister chromatid segregation (GO:0033046)3.23245876
119negative regulation of mitosis (GO:0045839)3.22440710
120mitotic spindle assembly checkpoint (GO:0007094)3.22387454
121spindle assembly checkpoint (GO:0071173)3.19770969
122negative regulation of translation, ncRNA-mediated (GO:0040033)3.19034874
123regulation of translation, ncRNA-mediated (GO:0045974)3.19034874
124negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.19034874
125sister chromatid cohesion (GO:0007062)3.18881943
126interkinetic nuclear migration (GO:0022027)3.18086636
127negative regulation of reproductive process (GO:2000242)3.17357058
128regulation of centrosome cycle (GO:0046605)3.15255887
129type B pancreatic cell development (GO:0003323)3.14982450
130negative regulation of smooth muscle cell differentiation (GO:0051151)3.14473356
131positive regulation of histone methylation (GO:0031062)3.14311852
132regulation of RNA export from nucleus (GO:0046831)3.13996423
133regulation of centriole replication (GO:0046599)3.13610088
134DNA catabolic process, exonucleolytic (GO:0000738)3.11415883
135maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.10530546
136DNA replication-dependent nucleosome assembly (GO:0006335)3.09713291
137DNA replication-dependent nucleosome organization (GO:0034723)3.09713291
138chromosome organization involved in meiosis (GO:0070192)3.08365980
139regulation of DNA endoreduplication (GO:0032875)2.99287952
140somatic hypermutation of immunoglobulin genes (GO:0016446)2.99172569
141somatic diversification of immune receptors via somatic mutation (GO:0002566)2.99172569
142regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.96990843
143regulation of mitotic spindle checkpoint (GO:1903504)2.96990843
144meiotic cell cycle process (GO:1903046)2.96728234
145mismatch repair (GO:0006298)2.95554071

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.27614257
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.99299760
3SALL1_21062744_ChIP-ChIP_HESCs_Human4.37639417
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.13131061
5AR_21909140_ChIP-Seq_LNCAP_Human3.77256665
6EZH2_22144423_ChIP-Seq_EOC_Human3.64398224
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.51307315
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.34480235
9E2F4_17652178_ChIP-ChIP_JURKAT_Human3.23366961
10MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.00709619
11KAP1_22055183_ChIP-Seq_ESCs_Mouse2.94935754
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.82234268
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.57994274
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.41355675
15HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.37385300
16SMAD_19615063_ChIP-ChIP_OVARY_Human2.35103272
17RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.29459707
18NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.28601493
19ELK1_19687146_ChIP-ChIP_HELA_Human2.27963182
20MYC_18555785_ChIP-Seq_MESCs_Mouse2.26594726
21TP63_19390658_ChIP-ChIP_HaCaT_Human2.26219466
22KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.10253578
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.08419553
24GATA1_26923725_Chip-Seq_HPCs_Mouse2.03582920
25PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.99457875
26HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.97849927
27CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.96351553
28FLI1_27457419_Chip-Seq_LIVER_Mouse1.91118781
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.85150292
30SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.84783251
31ETS1_20019798_ChIP-Seq_JURKAT_Human1.84064471
32HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.82558691
33E2F1_21310950_ChIP-Seq_MCF-7_Human1.81910134
34VDR_23849224_ChIP-Seq_CD4+_Human1.76868299
35FOXP3_21729870_ChIP-Seq_TREG_Human1.76284010
36TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.74632978
37PADI4_21655091_ChIP-ChIP_MCF-7_Human1.74245661
38FUS_26573619_Chip-Seq_HEK293_Human1.68659935
39MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.67749487
40JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.63177910
41SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.61975286
42MYC_19030024_ChIP-ChIP_MESCs_Mouse1.60232101
43RBPJ_22232070_ChIP-Seq_NCS_Mouse1.60019918
44PCGF2_27294783_Chip-Seq_ESCs_Mouse1.59891268
45ZNF274_21170338_ChIP-Seq_K562_Hela1.58345482
46MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.57080481
47POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.56782566
48HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.56254585
49TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.54920457
50YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.54314684
51AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.53868348
52CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.53063299
53FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.52087738
54MYC_19079543_ChIP-ChIP_MESCs_Mouse1.50776413
55RUNX1_26923725_Chip-Seq_HPCs_Mouse1.47032044
56POU3F2_20337985_ChIP-ChIP_501MEL_Human1.45771209
57EWS_26573619_Chip-Seq_HEK293_Human1.45518575
58FOXM1_26456572_ChIP-Seq_MCF-7_Human1.45510380
59THAP11_20581084_ChIP-Seq_MESCs_Mouse1.44386570
60TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.44157225
61MYC_18358816_ChIP-ChIP_MESCs_Mouse1.41771819
62MYC_18940864_ChIP-ChIP_HL60_Human1.41663165
63SUZ12_27294783_Chip-Seq_NPCs_Mouse1.38922405
64NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.38917330
65MYCN_18555785_ChIP-Seq_MESCs_Mouse1.38716980
66TAF15_26573619_Chip-Seq_HEK293_Human1.37865309
67RNF2_27304074_Chip-Seq_NSC_Mouse1.35152835
68* TTF2_22483619_ChIP-Seq_HELA_Human1.35010466
69MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.31635305
70CDX2_22108803_ChIP-Seq_LS180_Human1.30632109
71HOXB4_20404135_ChIP-ChIP_EML_Mouse1.28611876
72NFE2_27457419_Chip-Seq_LIVER_Mouse1.27829967
73DCP1A_22483619_ChIP-Seq_HELA_Human1.27022662
74NANOG_18555785_Chip-Seq_ESCs_Mouse1.25750354
75SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.25532686
76ESR1_20079471_ChIP-ChIP_T-47D_Human1.23990555
77NELFA_20434984_ChIP-Seq_ESCs_Mouse1.22977304
78TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.21472887
79LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.21371793
80CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.20859703
81EZH2_27294783_Chip-Seq_NPCs_Mouse1.20783816
82TCF3_18692474_ChIP-Seq_MESCs_Mouse1.19354779
83GABP_19822575_ChIP-Seq_HepG2_Human1.17833255
84STAT1_17558387_ChIP-Seq_HELA_Human1.16883899
85KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.16566379
86KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.16566379
87KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.16566379
88ELK4_26923725_Chip-Seq_MESODERM_Mouse1.15673814
89STAT3_23295773_ChIP-Seq_U87_Human1.14995043
90CTBP2_25329375_ChIP-Seq_LNCAP_Human1.13117682
91STAT6_21828071_ChIP-Seq_BEAS2B_Human1.12566885
92BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.12447527
93STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.12288913
94IGF1R_20145208_ChIP-Seq_DFB_Human1.11442566
95MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.10117112
96PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.09327339
97RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.08704568
98POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.07190866
99EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.05330352
100CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.05050290
101WT1_19549856_ChIP-ChIP_CCG9911_Human1.04735727
102TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.03903888
103AR_21572438_ChIP-Seq_LNCaP_Human1.03449434
104STAT3_18555785_Chip-Seq_ESCs_Mouse1.02283300
105E2F1_18555785_ChIP-Seq_MESCs_Mouse1.01390847
106NANOG_18555785_ChIP-Seq_MESCs_Mouse1.01141918
107P300_19829295_ChIP-Seq_ESCs_Human1.01020352
108IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.00340155
109CBP_20019798_ChIP-Seq_JUKART_Human1.00340155
110FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.00309840
111NANOG_21062744_ChIP-ChIP_HESCs_Human1.00282892
112BP1_19119308_ChIP-ChIP_Hs578T_Human1.00081544
113AUTS2_25519132_ChIP-Seq_293T-REX_Human1.00073330
114GF1B_26923725_Chip-Seq_HPCs_Mouse0.99941615
115CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.99512412
116NFYA_21822215_ChIP-Seq_K562_Human0.99241570
117KDM5A_27292631_Chip-Seq_BREAST_Human0.99168219
118ZNF217_24962896_ChIP-Seq_MCF-7_Human0.99046655
119EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.98826820
120TBL1_22424771_ChIP-Seq_293T_Human0.97935516
121E2F1_18555785_Chip-Seq_ESCs_Mouse0.97859802
122CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97791974
123GATA3_21867929_ChIP-Seq_TH1_Mouse0.97684723
124UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.97411495
125SRF_21415370_ChIP-Seq_HL-1_Mouse0.96968710
126MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.96790893
127KLF4_18555785_Chip-Seq_ESCs_Mouse0.96352289
128ETV1_20927104_ChIP-Seq_GIST48_Human0.95963895
129NMYC_18555785_Chip-Seq_ESCs_Mouse0.95712454
130SOX2_18555785_Chip-Seq_ESCs_Mouse0.95375258
131SALL4_18804426_ChIP-ChIP_XEN_Mouse0.95279178
132IRF1_19129219_ChIP-ChIP_H3396_Human0.95047366
133OCT4_18555785_Chip-Seq_ESCs_Mouse0.94125525
134ESRRB_18555785_Chip-Seq_ESCs_Mouse0.93947937
135XRN2_22483619_ChIP-Seq_HELA_Human0.93765409
136E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.93149402
137ELF1_17652178_ChIP-ChIP_JURKAT_Human0.92661497
138CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.91991282
139VDR_22108803_ChIP-Seq_LS180_Human0.91402926
140CTBP1_25329375_ChIP-Seq_LNCAP_Human0.91378430
141PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.90796427
142CTCF_18555785_Chip-Seq_ESCs_Mouse0.90456646
143EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.90311559
144HNFA_21074721_ChIP-Seq_CACO-2_Human0.89679385
145PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.88956880
146EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.88954362
147POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.88725344
148ZFX_18555785_Chip-Seq_ESCs_Mouse0.88421092
149TBX3_20139965_ChIP-Seq_ESCs_Mouse0.88208463
150NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.88181812
151SUZ12_18555785_Chip-Seq_ESCs_Mouse0.87462692
152KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.87380302
153POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.86940821
154TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86940821
155TBX3_20139965_ChIP-Seq_MESCs_Mouse0.86430571
156STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.85263483
157TCF3_18692474_ChIP-Seq_MEFs_Mouse0.85152432
158ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.85028260
159ER_23166858_ChIP-Seq_MCF-7_Human0.84372344
160CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.81825051
161ZFP57_27257070_Chip-Seq_ESCs_Mouse0.81697134
162SMAD4_21799915_ChIP-Seq_A2780_Human0.81686402
163TCF4_23295773_ChIP-Seq_U87_Human0.81129631
164GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.80557003
165PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.79307449
166KLF5_20875108_ChIP-Seq_MESCs_Mouse0.77186064
167* TOP2B_26459242_ChIP-Seq_MCF-7_Human0.75905247
168GBX2_23144817_ChIP-Seq_PC3_Human0.75827492

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003718_maternal_effect6.03457024
2MP0005451_abnormal_body_composition4.45393576
3MP0003693_abnormal_embryo_hatching4.27963339
4MP0010094_abnormal_chromosome_stability3.78487160
5MP0008877_abnormal_DNA_methylation3.73938720
6MP0002102_abnormal_ear_morphology3.37122393
7MP0008789_abnormal_olfactory_epithelium3.32645781
8MP0003787_abnormal_imprinting3.20773832
9MP0003646_muscle_fatigue3.19598359
10MP0003077_abnormal_cell_cycle3.14732498
11MP0003111_abnormal_nucleus_morphology2.92275004
12MP0000579_abnormal_nail_morphology2.88935494
13MP0004957_abnormal_blastocyst_morpholog2.71197164
14MP0005499_abnormal_olfactory_system2.70443092
15MP0005394_taste/olfaction_phenotype2.70443092
16MP0005395_other_phenotype2.61589010
17MP0001119_abnormal_female_reproductive2.56616601
18MP0005408_hypopigmentation2.51578519
19MP0003699_abnormal_female_reproductive2.48359713
20MP0006292_abnormal_olfactory_placode2.35663765
21MP0003121_genomic_imprinting2.24469014
22MP0001929_abnormal_gametogenesis2.09288654
23MP0000653_abnormal_sex_gland1.94581329
24MP0008057_abnormal_DNA_replication1.91687578
25MP0002938_white_spotting1.90653239
26MP0002210_abnormal_sex_determination1.89969693
27MP0000383_abnormal_hair_follicle1.89915290
28MP0003123_paternal_imprinting1.88025400
29MP0003315_abnormal_perineum_morphology1.87224640
30MP0008932_abnormal_embryonic_tissue1.84370393
31MP0003937_abnormal_limbs/digits/tail_de1.77540180
32MP0008995_early_reproductive_senescence1.76920886
33MP0002877_abnormal_melanocyte_morpholog1.75783129
34MP0002249_abnormal_larynx_morphology1.74564349
35MP0003941_abnormal_skin_development1.71766930
36MP0008007_abnormal_cellular_replicative1.70163524
37MP0002653_abnormal_ependyma_morphology1.69566267
38MP0000566_synostosis1.68341218
39MP0000372_irregular_coat_pigmentation1.67769060
40MP0001293_anophthalmia1.63779564
41MP0004264_abnormal_extraembryonic_tissu1.63481449
42MP0003786_premature_aging1.62686605
43MP0001529_abnormal_vocalization1.61907130
44MP0000350_abnormal_cell_proliferation1.56912575
45MP0010678_abnormal_skin_adnexa1.55956245
46MP0008058_abnormal_DNA_repair1.41932091
47MP0001730_embryonic_growth_arrest1.38689809
48MP0002085_abnormal_embryonic_tissue1.38593354
49MP0002234_abnormal_pharynx_morphology1.36789070
50MP0004147_increased_porphyrin_level1.36187840
51MP0010030_abnormal_orbit_morphology1.34883011
52MP0002161_abnormal_fertility/fecundity1.33758597
53MP0006276_abnormal_autonomic_nervous1.32058432
54MP0003136_yellow_coat_color1.31973590
55MP0003950_abnormal_plasma_membrane1.30319078
56MP0000427_abnormal_hair_cycle1.29121318
57MP0001145_abnormal_male_reproductive1.28352745
58MP0000678_abnormal_parathyroid_gland1.26268005
59MP0000631_abnormal_neuroendocrine_gland1.25470951
60MP0000462_abnormal_digestive_system1.22801818
61MP0002084_abnormal_developmental_patter1.20301787
62MP0005171_absent_coat_pigmentation1.16821807
63MP0001672_abnormal_embryogenesis/_devel1.16404432
64MP0005380_embryogenesis_phenotype1.16404432
65MP0009384_cardiac_valve_regurgitation1.16172661
66MP0005410_abnormal_fertilization1.14244001
67MP0001697_abnormal_embryo_size1.13863703
68MP0005646_abnormal_pituitary_gland1.12502522
69MP0003453_abnormal_keratinocyte_physiol1.11675075
70MP0002295_abnormal_pulmonary_circulatio1.09003173
71MP0000639_abnormal_adrenal_gland1.05632466
72MP0003755_abnormal_palate_morphology1.03292950
73MP0000049_abnormal_middle_ear1.01922294
74MP0004145_abnormal_muscle_electrophysio0.99314184
75MP0004185_abnormal_adipocyte_glucose0.96780105
76MP0003890_abnormal_embryonic-extraembry0.96764589
77MP0003119_abnormal_digestive_system0.94016479
78MP0000432_abnormal_head_morphology0.93543444
79MP0001346_abnormal_lacrimal_gland0.92613162
80MP0003385_abnormal_body_wall0.92463694
81MP0002019_abnormal_tumor_incidence0.92456460
82MP0005551_abnormal_eye_electrophysiolog0.92423697
83MP0002160_abnormal_reproductive_system0.90332901
84MP0001851_eye_inflammation0.89847445
85MP0009697_abnormal_copulation0.87388360
86MP0005187_abnormal_penis_morphology0.86697376
87MP0010368_abnormal_lymphatic_system0.85169711
88MP0002095_abnormal_skin_pigmentation0.83499764
89MP0001905_abnormal_dopamine_level0.81762298
90MP0005253_abnormal_eye_physiology0.81025933
91MP0002098_abnormal_vibrissa_morphology0.80950534
92MP0001915_intracranial_hemorrhage0.80607347
93MP0000490_abnormal_crypts_of0.79986471
94MP0002282_abnormal_trachea_morphology0.79627482
95MP0005248_abnormal_Harderian_gland0.79424863
96MP0002932_abnormal_joint_morphology0.78550289
97MP0003186_abnormal_redox_activity0.77264732
98MP0002177_abnormal_outer_ear0.76924103
99MP0001919_abnormal_reproductive_system0.76653651
100MP0003938_abnormal_ear_development0.75735982
101MP0004197_abnormal_fetal_growth/weight/0.74312207
102MP0003567_abnormal_fetal_cardiomyocyte0.74057735
103MP0000647_abnormal_sebaceous_gland0.73689759
104MP0003984_embryonic_growth_retardation0.72581848
105MP0009250_abnormal_appendicular_skeleto0.72527466
106MP0005389_reproductive_system_phenotype0.72493491
107MP0002086_abnormal_extraembryonic_tissu0.72013957
108MP0001849_ear_inflammation0.71754662
109MP0000627_abnormal_mammary_gland0.71012324
110MP0003698_abnormal_male_reproductive0.70814863
111MP0006035_abnormal_mitochondrial_morpho0.70288966
112MP0002751_abnormal_autonomic_nervous0.70103910
113MP0000377_abnormal_hair_follicle0.69740285
114MP0001216_abnormal_epidermal_layer0.69290966
115MP0002396_abnormal_hematopoietic_system0.68975942
116MP0003195_calcinosis0.68513479
117MP0002088_abnormal_embryonic_growth/wei0.67975300
118MP0001286_abnormal_eye_development0.67724323
119MP0010307_abnormal_tumor_latency0.66613663
120MP0006036_abnormal_mitochondrial_physio0.66256448
121MP0002111_abnormal_tail_morphology0.66077681
122MP0005621_abnormal_cell_physiology0.65663008
123MP0005397_hematopoietic_system_phenotyp0.65277243
124MP0001545_abnormal_hematopoietic_system0.65277243
125MP0002233_abnormal_nose_morphology0.64780211
126MP0000516_abnormal_urinary_system0.64723425
127MP0005367_renal/urinary_system_phenotyp0.64723425
128MP0003880_abnormal_central_pattern0.64502780
129MP0003935_abnormal_craniofacial_develop0.64120949
130MP0000767_abnormal_smooth_muscle0.62945023
131MP0001764_abnormal_homeostasis0.62769740
132MP0001485_abnormal_pinna_reflex0.62462053
133MP0000613_abnormal_salivary_gland0.62329635
134MP0005647_abnormal_sex_gland0.62174825
135MP0003936_abnormal_reproductive_system0.61778512
136MP0004133_heterotaxia0.61130198
137MP0002163_abnormal_gland_morphology0.60430204
138MP0002109_abnormal_limb_morphology0.59926522
139MP0002116_abnormal_craniofacial_bone0.59675325
140MP0003705_abnormal_hypodermis_morpholog0.59563568
141MP0006072_abnormal_retinal_apoptosis0.58823102
142MP0002080_prenatal_lethality0.58615113
143MP0005310_abnormal_salivary_gland0.58608114
144MP0000313_abnormal_cell_death0.57192155
145MP0003861_abnormal_nervous_system0.54227236
146MP0003566_abnormal_cell_adhesion0.53589193

Predicted human phenotypes

RankGene SetZ-score
1Male infertility (HP:0003251)6.94612263
2Papillary thyroid carcinoma (HP:0002895)5.39456936
3Chromsome breakage (HP:0040012)5.17799751
4Chromosomal breakage induced by crosslinking agents (HP:0003221)4.71645985
5Abnormality of the labia minora (HP:0012880)4.70582083
6Birth length less than 3rd percentile (HP:0003561)4.49934588
7Cortical dysplasia (HP:0002539)4.34914088
8Adrenal hypoplasia (HP:0000835)4.32823235
9Breast hypoplasia (HP:0003187)4.10529383
10Shawl scrotum (HP:0000049)3.96925925
11Abnormal gallbladder physiology (HP:0012438)3.87573602
12Cholecystitis (HP:0001082)3.87573602
13Premature ovarian failure (HP:0008209)3.79458824
14Lip pit (HP:0100267)3.75576024
15Patellar aplasia (HP:0006443)3.71712702
16Facial hemangioma (HP:0000329)3.59235656
17Aplasia/Hypoplasia of the patella (HP:0006498)3.36215847
18Aplasia/Hypoplasia of the sternum (HP:0006714)3.27689506
19Abnormality of chromosome segregation (HP:0002916)3.24626178
20Flat capital femoral epiphysis (HP:0003370)3.23887641
21Acute myeloid leukemia (HP:0004808)3.07539414
22Secondary amenorrhea (HP:0000869)2.96427785
23Abnormality of chromosome stability (HP:0003220)2.91014895
24Abnormality of the fingertips (HP:0001211)2.87487709
25Oligodactyly (hands) (HP:0001180)2.82578004
26Abnormality of the preputium (HP:0100587)2.82414528
27Thyroid carcinoma (HP:0002890)2.82172657
28Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.80350866
29Rhabdomyosarcoma (HP:0002859)2.75187906
30Sandal gap (HP:0001852)2.70162474
31Hypergonadotropic hypogonadism (HP:0000815)2.68280016
32Capillary hemangiomas (HP:0005306)2.68188604
33Aplasia/Hypoplasia of the breasts (HP:0010311)2.66873526
34Breast aplasia (HP:0100783)2.65112918
35Oligodactyly (HP:0012165)2.62613002
36Aplasia/Hypoplasia of the uvula (HP:0010293)2.57786020
37Ectopic kidney (HP:0000086)2.54947103
38Arterial tortuosity (HP:0005116)2.50758080
39Infertility (HP:0000789)2.49951962
40Midline defect of the nose (HP:0004122)2.48513239
41Small intestinal stenosis (HP:0012848)2.47894689
42Duodenal stenosis (HP:0100867)2.47894689
43Supernumerary spleens (HP:0009799)2.46221191
44Absent radius (HP:0003974)2.45916437
45Absent septum pellucidum (HP:0001331)2.45799952
46Abdominal situs inversus (HP:0003363)2.45059931
47Abnormality of abdominal situs (HP:0011620)2.45059931
48Abnormality of cochlea (HP:0000375)2.44909524
49Reticulocytopenia (HP:0001896)2.43965865
50Pulmonary fibrosis (HP:0002206)2.43927800
51Triphalangeal thumb (HP:0001199)2.39781117
52Median cleft lip (HP:0000161)2.38362033
53Septo-optic dysplasia (HP:0100842)2.38356994
54Meckel diverticulum (HP:0002245)2.36217466
55Insulin-resistant diabetes mellitus (HP:0000831)2.35576686
56Aplasia involving forearm bones (HP:0009822)2.31368866
57Absent forearm bone (HP:0003953)2.31368866
58Short thumb (HP:0009778)2.31159480
59Pancreatic fibrosis (HP:0100732)2.27444012
60Hypoplasia of the pons (HP:0012110)2.26999886
61Vascular tortuosity (HP:0004948)2.25309740
62Nephroblastoma (Wilms tumor) (HP:0002667)2.21716412
63Abnormality of the pons (HP:0007361)2.21080220
64Abnormality of the septum pellucidum (HP:0007375)2.20022618
65Abnormality of the ileum (HP:0001549)2.19302535
66Sparse lateral eyebrow (HP:0005338)2.18441163
67Clubbing of toes (HP:0100760)2.17231543
68Myelodysplasia (HP:0002863)2.16818253
69Sloping forehead (HP:0000340)2.13987321
70Cystic hygroma (HP:0000476)2.13265407
71Pancreatic cysts (HP:0001737)2.12870173
72Abnormality of midbrain morphology (HP:0002418)2.12785311
73Molar tooth sign on MRI (HP:0002419)2.12785311
74Prostate neoplasm (HP:0100787)2.10980483
75Colon cancer (HP:0003003)2.10131395
76Depressed nasal tip (HP:0000437)2.08385201
77Wrist flexion contracture (HP:0001239)2.04634405
78Impulsivity (HP:0100710)2.04377990
79Medulloblastoma (HP:0002885)2.03883057
80Bifid tongue (HP:0010297)2.03574871
81Homocystinuria (HP:0002156)2.03359245
82Abnormality of homocysteine metabolism (HP:0010919)2.03359245
83Increased nuchal translucency (HP:0010880)2.03168915
84Abnormal lung lobation (HP:0002101)2.02759279
85Embryonal renal neoplasm (HP:0011794)2.01733633
86Neoplasm of the adrenal cortex (HP:0100641)2.01627497
87Primary amenorrhea (HP:0000786)2.00740911
88Abnormality of lateral ventricle (HP:0030047)2.00499991
89Absent thumb (HP:0009777)1.96396433
90Aplasia/Hypoplasia of the tibia (HP:0005772)1.92599075
91Methylmalonic acidemia (HP:0002912)1.92194898
92Transitional cell carcinoma of the bladder (HP:0006740)1.91330578
93Abnormality of sulfur amino acid metabolism (HP:0004339)1.91058459
94Abnormality of the duodenum (HP:0002246)1.90772350
95Preaxial hand polydactyly (HP:0001177)1.90478093
96Abnormality of DNA repair (HP:0003254)1.90263293
97Amniotic constriction ring (HP:0009775)1.90228283
98Abnormality of placental membranes (HP:0011409)1.90228283
99Combined immunodeficiency (HP:0005387)1.90110651
100Abnormality of the labia (HP:0000058)1.90078295
101Glioma (HP:0009733)1.89998877
102Neoplasm of striated muscle (HP:0009728)1.89648613
103Neoplasm of the oral cavity (HP:0100649)1.89327247
104Abnormality of the proximal phalanges of the hand (HP:0009834)1.89176446
105Ependymoma (HP:0002888)1.88542487
106Aplasia/Hypoplasia of the tongue (HP:0010295)1.88293272
107Bladder neoplasm (HP:0009725)1.87249554
108Bladder carcinoma (HP:0002862)1.87249554
109Horseshoe kidney (HP:0000085)1.87061564
110Gonadotropin excess (HP:0000837)1.85684756
111Arteriovenous malformation (HP:0100026)1.85541464
112Genital tract atresia (HP:0001827)1.85128871
113Milia (HP:0001056)1.84854107
114Blepharitis (HP:0000498)1.83685557
115Short tibia (HP:0005736)1.83241510
116Abnormality of the carotid arteries (HP:0005344)1.82788854
117Abnormality of the labia majora (HP:0012881)1.82722343
118Medial flaring of the eyebrow (HP:0010747)1.81794459
119Aplasia involving bones of the extremities (HP:0009825)1.81619051
120Aplasia involving bones of the upper limbs (HP:0009823)1.81619051
121Aplasia of the phalanges of the hand (HP:0009802)1.81619051
122Uterine leiomyosarcoma (HP:0002891)1.81289313
123Leiomyosarcoma (HP:0100243)1.81289313
124Microtia (HP:0008551)1.79183096
125Hypoplastic labia majora (HP:0000059)1.79106738
126Aplasia/Hypoplasia of the earlobes (HP:0009906)1.78737987
127Morphological abnormality of the inner ear (HP:0011390)1.78485350
128Spondylolisthesis (HP:0003302)1.77617385
129Duplicated collecting system (HP:0000081)1.76706198
130Aganglionic megacolon (HP:0002251)1.76520699
131Dyschromatopsia (HP:0007641)1.76374496
132Short middle phalanx of the 5th finger (HP:0004220)1.76114417
133Hypoplasia of the fovea (HP:0007750)1.76035245
134Aplasia/Hypoplasia of the fovea (HP:0008060)1.76035245
135Limb hypertonia (HP:0002509)1.75693394
136Astrocytoma (HP:0009592)1.75580252
137Abnormality of the astrocytes (HP:0100707)1.75580252
138Optic nerve hypoplasia (HP:0000609)1.75298181
139Cafe-au-lait spot (HP:0000957)1.74876403
140Rib fusion (HP:0000902)1.74798359
141Sclerocornea (HP:0000647)1.74452380
142Oculomotor apraxia (HP:0000657)1.74359007
143Congenital primary aphakia (HP:0007707)1.72748133
144Choanal atresia (HP:0000453)1.72584182
145Small hand (HP:0200055)1.72199332
146Chin dimple (HP:0010751)1.72000476
147Bicornuate uterus (HP:0000813)1.71486710
148Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.70954087
149Volvulus (HP:0002580)1.70889748
150Abnormality of the epiphysis of the femoral head (HP:0010574)1.70759866
151Duplication of thumb phalanx (HP:0009942)1.70456339
152Sensory axonal neuropathy (HP:0003390)1.70114027
153Abnormal biliary tract physiology (HP:0012439)1.69680181
154Bile duct proliferation (HP:0001408)1.69680181
155Sparse scalp hair (HP:0002209)1.69590273
156Postaxial foot polydactyly (HP:0001830)1.69358017
157Intestinal atresia (HP:0011100)1.68581138
158Abnormality of the parathyroid morphology (HP:0011766)1.67728226
159Poor coordination (HP:0002370)1.67129527
160Stenosis of the external auditory canal (HP:0000402)1.66757756

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS14.66038680
2MAP3K64.15629707
3TTK3.87687908
4STK38L3.81870033
5LATS23.71180134
6MUSK3.70202907
7PLK43.61988420
8ERBB43.45134676
9CDC73.13533836
10BRAF2.74248586
11ZAK2.72695700
12TAOK32.69668051
13VRK22.66425816
14WNK32.25141424
15TNIK2.12419130
16EEF2K2.11715008
17KSR22.11411080
18CHEK22.04689472
19SRPK12.04263180
20STK101.98912936
21MAP3K91.96982252
22MST41.89541143
23CCNB11.89225556
24MELK1.80753323
25TAOK11.77933185
26WEE11.72846890
27STK31.72591886
28RAF11.67178934
29MOS1.66627713
30MAPKAPK31.66286432
31MKNK11.64042859
32MKNK21.63969907
33PLK11.60201149
34MAP3K131.54213606
35DMPK1.53153399
36BMPR21.48149886
37EIF2AK31.42203015
38NEK91.38593022
39CDK91.37768493
40PNCK1.37520456
41NEK21.28019958
42BRD41.26512685
43MAP3K81.17222122
44NME11.17010666
45TRIM281.16850927
46ACVR1B1.14119828
47AURKB1.12560016
48NTRK31.11761168
49STK241.08028350
50BRSK11.07312513
51TRPM71.06680322
52PAK61.06478428
53TESK21.04994035
54CLK11.04031950
55VRK11.03540345
56STK161.02004736
57STK381.01340969
58KSR11.01031734
59PBK1.00421644
60CDK120.99039681
61PLK30.97251092
62TYRO30.96417291
63CDK80.94410321
64ARAF0.93030446
65MAPKAPK50.84573257
66CHEK10.80006119
67PRKD30.79067119
68MAP3K40.78306191
69ATM0.78278350
70NUAK10.78242498
71NLK0.73336642
72RPS6KB20.71803772
73DYRK20.71708629
74MAPK130.70421258
75CSNK1G10.68491359
76AURKA0.66992783
77STK390.66405519
78MAP4K20.65906838
79CDK30.65455082
80CAMK1G0.65218227
81BUB10.64157424
82DYRK30.62061104
83PLK20.61633902
84RPS6KA40.59302293
85PKN10.57667858
86PRKAA10.56338727
87TSSK60.55429883
88PRKCI0.55387536
89CSNK2A20.54844148
90CDK40.54825865
91PRKAA20.54412861
92CSNK2A10.54300874
93ABL20.53375876
94RET0.53026091
95FLT30.53007729
96PDK20.52949272
97MARK30.52930053
98NEK60.52860849
99WNK40.51690086
100BCR0.50583230
101EIF2AK10.49917179
102ATR0.46972239
103CDK70.46945346
104CDK10.46817670
105CDK20.46006660
106PRKACB0.45897883
107ERBB30.45070009
108PIM10.42168361
109MARK20.41861971
110TGFBR10.41515104
111MAP3K50.40202427
112PRKDC0.40137642
113CSNK1G30.39711733
114EPHA40.39698399
115INSRR0.38500411
116CDK60.37001133
117ILK0.36317395
118MET0.35890491
119FGFR10.35747507
120CSNK1G20.35186852
121EIF2AK20.35025798
122TEC0.34751224
123CSNK1D0.34665374
124CSNK1A1L0.34049357
125PRKD20.33461114
126ABL10.32882407
127STK40.32579230
128RIPK40.31491184
129NTRK20.30977637
130MAP2K70.27550764
131AKT10.24741831
132CHUK0.24486774
133BMPR1B0.24331275
134MST1R0.23588334
135BRSK20.22636006
136NEK10.22410945
137FRK0.21463354
138MAPK100.21287659
139MAPK140.21052227
140GSK3B0.19350923
141CSNK1E0.18216198
142MAPK10.17879444
143JAK30.16124421
144MAP2K40.16111845

Predicted pathways (KEGG)

RankGene SetZ-score
1Cell cycle_Homo sapiens_hsa041104.36430472
2RNA degradation_Homo sapiens_hsa030183.70037467
3Basal transcription factors_Homo sapiens_hsa030223.69844152
4Ovarian steroidogenesis_Homo sapiens_hsa049132.97957270
5Fanconi anemia pathway_Homo sapiens_hsa034602.89233661
6Non-homologous end-joining_Homo sapiens_hsa034502.86032727
7Homologous recombination_Homo sapiens_hsa034402.82930294
8Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.63019573
9p53 signaling pathway_Homo sapiens_hsa041152.54090407
10Linoleic acid metabolism_Homo sapiens_hsa005912.40421710
11alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.39972577
12Ether lipid metabolism_Homo sapiens_hsa005652.23251562
13Vitamin B6 metabolism_Homo sapiens_hsa007502.10310704
14RNA transport_Homo sapiens_hsa030132.07025974
15Oocyte meiosis_Homo sapiens_hsa041142.05373932
16Pancreatic cancer_Homo sapiens_hsa052122.03870844
17Progesterone-mediated oocyte maturation_Homo sapiens_hsa049142.02496184
18Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.98291901
19Circadian rhythm_Homo sapiens_hsa047101.89226841
20TGF-beta signaling pathway_Homo sapiens_hsa043501.88568188
21Dorso-ventral axis formation_Homo sapiens_hsa043201.87768808
22DNA replication_Homo sapiens_hsa030301.82596297
23MicroRNAs in cancer_Homo sapiens_hsa052061.75645497
24Mismatch repair_Homo sapiens_hsa034301.74763741
25Ribosome_Homo sapiens_hsa030101.74596561
26Thyroid cancer_Homo sapiens_hsa052161.73726265
27Protein export_Homo sapiens_hsa030601.70488599
28Steroid biosynthesis_Homo sapiens_hsa001001.69973207
29Propanoate metabolism_Homo sapiens_hsa006401.55877053
30Parkinsons disease_Homo sapiens_hsa050121.53847835
31Huntingtons disease_Homo sapiens_hsa050161.50947889
32Oxidative phosphorylation_Homo sapiens_hsa001901.50615663
33Base excision repair_Homo sapiens_hsa034101.50192029
34Olfactory transduction_Homo sapiens_hsa047401.48549537
35Colorectal cancer_Homo sapiens_hsa052101.37030711
36Proteasome_Homo sapiens_hsa030501.29883763
37RNA polymerase_Homo sapiens_hsa030201.29362598
38Adherens junction_Homo sapiens_hsa045201.26246416
39Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.22227372
40Choline metabolism in cancer_Homo sapiens_hsa052311.21073228
41Caffeine metabolism_Homo sapiens_hsa002321.20344894
42Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.17383483
43Hippo signaling pathway_Homo sapiens_hsa043901.16826202
44Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.15094192
45GnRH signaling pathway_Homo sapiens_hsa049121.14958561
46Nucleotide excision repair_Homo sapiens_hsa034201.13394045
47Pyruvate metabolism_Homo sapiens_hsa006201.08079005
48Prolactin signaling pathway_Homo sapiens_hsa049171.07373421
49Selenocompound metabolism_Homo sapiens_hsa004501.05168023
50Small cell lung cancer_Homo sapiens_hsa052221.03267847
51Renal cell carcinoma_Homo sapiens_hsa052110.99250880
52Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.97114551
53FoxO signaling pathway_Homo sapiens_hsa040680.96929333
54Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.95762751
55Endometrial cancer_Homo sapiens_hsa052130.91108249
56Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.90211640
57Phototransduction_Homo sapiens_hsa047440.87314491
58Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.85833494
59HTLV-I infection_Homo sapiens_hsa051660.85066516
60Butanoate metabolism_Homo sapiens_hsa006500.84238703
61Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.83514392
62mRNA surveillance pathway_Homo sapiens_hsa030150.82444113
63Ras signaling pathway_Homo sapiens_hsa040140.80549043
64Fatty acid elongation_Homo sapiens_hsa000620.80291956
65Cysteine and methionine metabolism_Homo sapiens_hsa002700.77410997
66Basal cell carcinoma_Homo sapiens_hsa052170.76371092
67Alzheimers disease_Homo sapiens_hsa050100.74907285
68VEGF signaling pathway_Homo sapiens_hsa043700.72686892
69Lysine degradation_Homo sapiens_hsa003100.70931688
70Arachidonic acid metabolism_Homo sapiens_hsa005900.70693456
71Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.69941296
72Prostate cancer_Homo sapiens_hsa052150.68860916
73Bladder cancer_Homo sapiens_hsa052190.68327789
74Folate biosynthesis_Homo sapiens_hsa007900.67390348
75Glycerophospholipid metabolism_Homo sapiens_hsa005640.65809496
76Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.65778605
77Thyroid hormone signaling pathway_Homo sapiens_hsa049190.64114402
78Tight junction_Homo sapiens_hsa045300.63816418
79Nicotine addiction_Homo sapiens_hsa050330.62435499
80Phospholipase D signaling pathway_Homo sapiens_hsa040720.62286582
81Pathways in cancer_Homo sapiens_hsa052000.61234695
82Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.60524075
83One carbon pool by folate_Homo sapiens_hsa006700.60080904
84Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.59762793
85Long-term depression_Homo sapiens_hsa047300.59293429
86Transcriptional misregulation in cancer_Homo sapiens_hsa052020.59193228
87Viral carcinogenesis_Homo sapiens_hsa052030.58842613
88Non-small cell lung cancer_Homo sapiens_hsa052230.58241044
89ErbB signaling pathway_Homo sapiens_hsa040120.58097396
90Herpes simplex infection_Homo sapiens_hsa051680.57663049
91Glutathione metabolism_Homo sapiens_hsa004800.57377785
92Chronic myeloid leukemia_Homo sapiens_hsa052200.57199835
93Nitrogen metabolism_Homo sapiens_hsa009100.56728503
94Pyrimidine metabolism_Homo sapiens_hsa002400.55899675
95Longevity regulating pathway - mammal_Homo sapiens_hsa042110.55250273
96Estrogen signaling pathway_Homo sapiens_hsa049150.54873011
97Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.53814684
98Notch signaling pathway_Homo sapiens_hsa043300.53730252
99Metabolic pathways_Homo sapiens_hsa011000.53555009
100Hedgehog signaling pathway_Homo sapiens_hsa043400.53344003
101Cardiac muscle contraction_Homo sapiens_hsa042600.52536476
102Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52258495
103Purine metabolism_Homo sapiens_hsa002300.51826644
104Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.49618042
105mTOR signaling pathway_Homo sapiens_hsa041500.49455209
106Taste transduction_Homo sapiens_hsa047420.48590260
107Hepatitis B_Homo sapiens_hsa051610.47130993
108Melanoma_Homo sapiens_hsa052180.46650434
109Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.45229365
110Inositol phosphate metabolism_Homo sapiens_hsa005620.44337337
111Amoebiasis_Homo sapiens_hsa051460.42071390
112Sphingolipid metabolism_Homo sapiens_hsa006000.41154499
113Regulation of autophagy_Homo sapiens_hsa041400.40674234
114Fatty acid metabolism_Homo sapiens_hsa012120.40650646
115Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.40618036
116Vascular smooth muscle contraction_Homo sapiens_hsa042700.39447252
117Wnt signaling pathway_Homo sapiens_hsa043100.39444149
118Regulation of actin cytoskeleton_Homo sapiens_hsa048100.39380164
119Jak-STAT signaling pathway_Homo sapiens_hsa046300.37998181
120Serotonergic synapse_Homo sapiens_hsa047260.37971362
121GABAergic synapse_Homo sapiens_hsa047270.37459492
122MAPK signaling pathway_Homo sapiens_hsa040100.36217378
123Other glycan degradation_Homo sapiens_hsa005110.35092720
124Epstein-Barr virus infection_Homo sapiens_hsa051690.33653633
125Carbon metabolism_Homo sapiens_hsa012000.33312640
126Sphingolipid signaling pathway_Homo sapiens_hsa040710.33121823
127Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.29994270
128Rap1 signaling pathway_Homo sapiens_hsa040150.28706608
129Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.28514525
130NOD-like receptor signaling pathway_Homo sapiens_hsa046210.27266908
131Toxoplasmosis_Homo sapiens_hsa051450.26977407
132Spliceosome_Homo sapiens_hsa030400.26715082
133Sulfur metabolism_Homo sapiens_hsa009200.26485876
134Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.25859013
135Glioma_Homo sapiens_hsa052140.25837356
136Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.25740436
137Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.25215585
138Biosynthesis of amino acids_Homo sapiens_hsa012300.23944795
139Maturity onset diabetes of the young_Homo sapiens_hsa049500.23688619
1402-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.22795691
141TNF signaling pathway_Homo sapiens_hsa046680.22765425
142Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.20902283
143Phosphatidylinositol signaling system_Homo sapiens_hsa040700.20773211
144Peroxisome_Homo sapiens_hsa041460.19987432
145Proteoglycans in cancer_Homo sapiens_hsa052050.19222485
146Alcoholism_Homo sapiens_hsa050340.14901592
147Morphine addiction_Homo sapiens_hsa050320.14855998
148N-Glycan biosynthesis_Homo sapiens_hsa005100.13991675
149Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.10944280
150Arginine and proline metabolism_Homo sapiens_hsa003300.08635130
151ABC transporters_Homo sapiens_hsa020100.07851778
152Collecting duct acid secretion_Homo sapiens_hsa049660.06236343
153Fatty acid biosynthesis_Homo sapiens_hsa000610.05332331

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