Rank | Gene Set | Z-score |
---|---|---|
1 | locomotory exploration behavior (GO:0035641) | 6.48439263 |
2 | synaptic vesicle maturation (GO:0016188) | 6.47507683 |
3 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 6.42291644 |
4 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 6.16837799 |
5 | vocalization behavior (GO:0071625) | 5.84067517 |
6 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.65393161 |
7 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 5.61685550 |
8 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 5.37113672 |
9 | regulation of glutamate receptor signaling pathway (GO:1900449) | 5.27105196 |
10 | synaptic vesicle exocytosis (GO:0016079) | 5.25652882 |
11 | glutamate secretion (GO:0014047) | 5.23970790 |
12 | exploration behavior (GO:0035640) | 4.93723542 |
13 | protein localization to synapse (GO:0035418) | 4.93659771 |
14 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.92897095 |
15 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.88000737 |
16 | dendritic spine morphogenesis (GO:0060997) | 4.83940196 |
17 | layer formation in cerebral cortex (GO:0021819) | 4.80465372 |
18 | regulation of synapse structural plasticity (GO:0051823) | 4.68417684 |
19 | * regulation of neuronal synaptic plasticity (GO:0048168) | 4.65669648 |
20 | * regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.49647472 |
21 | synaptic transmission, glutamatergic (GO:0035249) | 4.38327615 |
22 | neuron cell-cell adhesion (GO:0007158) | 4.37291664 |
23 | regulation of synaptic vesicle transport (GO:1902803) | 4.33454415 |
24 | neurotransmitter secretion (GO:0007269) | 4.29839632 |
25 | neurotransmitter-gated ion channel clustering (GO:0072578) | 4.26283705 |
26 | cerebellar granule cell differentiation (GO:0021707) | 4.19759741 |
27 | glutamate receptor signaling pathway (GO:0007215) | 4.17283328 |
28 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.10795868 |
29 | long-term memory (GO:0007616) | 4.07944181 |
30 | positive regulation of membrane potential (GO:0045838) | 4.07500286 |
31 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 4.00764515 |
32 | neuronal action potential propagation (GO:0019227) | 4.00746063 |
33 | regulation of dendritic spine morphogenesis (GO:0061001) | 4.00013857 |
34 | neuron-neuron synaptic transmission (GO:0007270) | 3.92252951 |
35 | proline transport (GO:0015824) | 3.89971247 |
36 | positive regulation of synapse maturation (GO:0090129) | 3.80599382 |
37 | gamma-aminobutyric acid transport (GO:0015812) | 3.80154717 |
38 | regulation of postsynaptic membrane potential (GO:0060078) | 3.77907708 |
39 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.77526087 |
40 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.75912942 |
41 | neuromuscular process controlling balance (GO:0050885) | 3.74530908 |
42 | * regulation of synaptic plasticity (GO:0048167) | 3.71036777 |
43 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.69594593 |
44 | auditory behavior (GO:0031223) | 3.66053003 |
45 | cellular potassium ion homeostasis (GO:0030007) | 3.65290961 |
46 | sodium ion export (GO:0071436) | 3.60881886 |
47 | neuron recognition (GO:0008038) | 3.60431822 |
48 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 3.58988280 |
49 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.57713514 |
50 | dendritic spine organization (GO:0097061) | 3.57098147 |
51 | postsynaptic membrane organization (GO:0001941) | 3.50473436 |
52 | activation of protein kinase A activity (GO:0034199) | 3.49968680 |
53 | dendrite morphogenesis (GO:0048813) | 3.48436281 |
54 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.46672627 |
55 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.45885024 |
56 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.45207837 |
57 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.44736903 |
58 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.41964284 |
59 | axonal fasciculation (GO:0007413) | 3.41370886 |
60 | positive regulation of dendritic spine development (GO:0060999) | 3.41216673 |
61 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.39424981 |
62 | neurotransmitter transport (GO:0006836) | 3.37668741 |
63 | transmission of nerve impulse (GO:0019226) | 3.36371366 |
64 | regulation of dendritic spine development (GO:0060998) | 3.35530525 |
65 | response to auditory stimulus (GO:0010996) | 3.35520197 |
66 | long-term synaptic potentiation (GO:0060291) | 3.34639842 |
67 | regulation of neurotransmitter secretion (GO:0046928) | 3.33867250 |
68 | innervation (GO:0060384) | 3.33389447 |
69 | synaptic vesicle endocytosis (GO:0048488) | 3.33316908 |
70 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.32290422 |
71 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.29615238 |
72 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.28262563 |
73 | neuronal ion channel clustering (GO:0045161) | 3.27998977 |
74 | cell communication by electrical coupling (GO:0010644) | 3.26951718 |
75 | chemosensory behavior (GO:0007635) | 3.24952365 |
76 | positive regulation of neurotransmitter transport (GO:0051590) | 3.24785409 |
77 | prepulse inhibition (GO:0060134) | 3.22197606 |
78 | regulation of ARF protein signal transduction (GO:0032012) | 3.20680044 |
79 | regulation of vesicle fusion (GO:0031338) | 3.18851476 |
80 | behavioral defense response (GO:0002209) | 3.18327020 |
81 | behavioral fear response (GO:0001662) | 3.18327020 |
82 | membrane depolarization (GO:0051899) | 3.15736950 |
83 | regulation of neurotransmitter levels (GO:0001505) | 3.15468560 |
84 | amino acid import (GO:0043090) | 3.11364813 |
85 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.09944230 |
86 | regulation of neurotransmitter transport (GO:0051588) | 3.07355481 |
87 | glycine transport (GO:0015816) | 3.04982552 |
88 | regulation of ARF GTPase activity (GO:0032312) | 3.04655396 |
89 | social behavior (GO:0035176) | 3.03966127 |
90 | intraspecies interaction between organisms (GO:0051703) | 3.03966127 |
91 | cell migration in hindbrain (GO:0021535) | 3.03785470 |
92 | * learning (GO:0007612) | 3.03371570 |
93 | membrane hyperpolarization (GO:0060081) | 3.02941121 |
94 | neuromuscular process (GO:0050905) | 3.02773333 |
95 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.02714460 |
96 | L-amino acid import (GO:0043092) | 3.02156694 |
97 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.01365363 |
98 | membrane depolarization during action potential (GO:0086010) | 3.01175270 |
99 | positive regulation of synaptic transmission (GO:0050806) | 2.99380831 |
100 | regulation of female receptivity (GO:0045924) | 2.98331397 |
101 | fear response (GO:0042596) | 2.95295805 |
102 | * regulation of synaptic transmission (GO:0050804) | 2.93677339 |
103 | synapse assembly (GO:0007416) | 2.92528751 |
104 | vesicle transport along microtubule (GO:0047496) | 2.92023533 |
105 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.91096002 |
106 | response to histamine (GO:0034776) | 2.88351868 |
107 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.85938884 |
108 | regulation of synapse maturation (GO:0090128) | 2.85830101 |
109 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.85282062 |
110 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.80152198 |
111 | histone H3-K36 demethylation (GO:0070544) | 2.78185580 |
112 | semaphorin-plexin signaling pathway (GO:0071526) | 2.76938828 |
113 | cell-cell junction maintenance (GO:0045217) | 2.75811762 |
114 | protein-DNA complex disassembly (GO:0032986) | 2.74569929 |
115 | nucleosome disassembly (GO:0006337) | 2.74569929 |
116 | negative regulation of histone methylation (GO:0031061) | 2.71740869 |
117 | regulation of histone H3-K27 methylation (GO:0061085) | 2.69733754 |
118 | convergent extension (GO:0060026) | 2.69503887 |
119 | cell differentiation in hindbrain (GO:0021533) | 2.69424839 |
120 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.68922102 |
121 | adherens junction assembly (GO:0034333) | 2.63937109 |
122 | negative regulation of dendrite morphogenesis (GO:0050774) | 2.54266053 |
123 | dopamine receptor signaling pathway (GO:0007212) | 2.50035731 |
124 | neural tube development (GO:0021915) | 2.49019524 |
125 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.48000948 |
126 | presynaptic membrane assembly (GO:0097105) | 2.47721906 |
127 | positive regulation of Rap GTPase activity (GO:0032854) | 2.46937432 |
128 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.46671988 |
129 | histone H3-K9 demethylation (GO:0033169) | 2.46316323 |
130 | positive regulation of gene expression, epigenetic (GO:0045815) | 2.45936113 |
131 | generation of neurons (GO:0048699) | 2.44767768 |
132 | pre-miRNA processing (GO:0031054) | 2.42136959 |
133 | establishment of nucleus localization (GO:0040023) | 2.40900770 |
134 | histone H4 deacetylation (GO:0070933) | 2.40449396 |
135 | positive regulation of dendrite development (GO:1900006) | 2.39380889 |
136 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.39102182 |
137 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.38804821 |
138 | histone lysine demethylation (GO:0070076) | 2.38217868 |
139 | signal complex assembly (GO:0007172) | 2.37340331 |
140 | positive regulation of dendrite morphogenesis (GO:0050775) | 2.37326815 |
141 | mannose metabolic process (GO:0006013) | 2.36760723 |
142 | cell-substrate adherens junction assembly (GO:0007045) | 2.36706103 |
143 | focal adhesion assembly (GO:0048041) | 2.36706103 |
144 | camera-type eye morphogenesis (GO:0048593) | 2.36243927 |
145 | protein targeting to plasma membrane (GO:0072661) | 2.33016200 |
146 | regulation of dendrite morphogenesis (GO:0048814) | 2.31872943 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.20894012 |
2 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.10967845 |
3 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.08014407 |
4 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.03772837 |
5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.97791786 |
6 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.86328283 |
7 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.83532838 |
8 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.79372981 |
9 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.79372981 |
10 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.75310619 |
11 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.71791424 |
12 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.68541356 |
13 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.57039610 |
14 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.54927826 |
15 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.53354726 |
16 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.51697971 |
17 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.49810856 |
18 | * KDM2B_26808549_Chip-Seq_DND41_Human | 2.44332173 |
19 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.43810546 |
20 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.40908505 |
21 | * MYC_22102868_ChIP-Seq_BL_Human | 2.34123410 |
22 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.33673577 |
23 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.32227898 |
24 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.31442839 |
25 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.30792634 |
26 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.30649699 |
27 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.27777199 |
28 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.24636055 |
29 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.24364409 |
30 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.19100978 |
31 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.16505288 |
32 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.15395621 |
33 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.14808446 |
34 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.08875306 |
35 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.07354860 |
36 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.99456456 |
37 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.91901366 |
38 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.91136324 |
39 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.85095153 |
40 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.84562007 |
41 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.83935917 |
42 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.81383844 |
43 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.78022342 |
44 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.70324933 |
45 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.69722022 |
46 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.59446588 |
47 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.58356078 |
48 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.53074958 |
49 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.51141888 |
50 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.47693122 |
51 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.46716128 |
52 | P68_20966046_ChIP-Seq_HELA_Human | 1.45969100 |
53 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.44059285 |
54 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.43212982 |
55 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.42884485 |
56 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.39820670 |
57 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.38884839 |
58 | KDM2B_26808549_Chip-Seq_K562_Human | 1.37187491 |
59 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.36896063 |
60 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.36804252 |
61 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.34619098 |
62 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.33864623 |
63 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.32269702 |
64 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.31927382 |
65 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.31699552 |
66 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.30388030 |
67 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.29735265 |
68 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.28753444 |
69 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.27800956 |
70 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.26015439 |
71 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.25809315 |
72 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.25236686 |
73 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.25067784 |
74 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.24132588 |
75 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.23436800 |
76 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.23208246 |
77 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.23162444 |
78 | * AR_19668381_ChIP-Seq_PC3_Human | 1.22991130 |
79 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.22763108 |
80 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.22646793 |
81 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.22551177 |
82 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.16123186 |
83 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.15388734 |
84 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.14495750 |
85 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.13955062 |
86 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.12699027 |
87 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.10227621 |
88 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.09985912 |
89 | MAF_26560356_Chip-Seq_TH1_Human | 1.09844500 |
90 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.09838145 |
91 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.09808968 |
92 | STAT3_23295773_ChIP-Seq_U87_Human | 1.09471920 |
93 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.09214187 |
94 | UTX_26944678_Chip-Seq_JUKART_Human | 1.08572031 |
95 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.07834128 |
96 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.07323529 |
97 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.07038735 |
98 | AR_25329375_ChIP-Seq_VCAP_Human | 1.06982507 |
99 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.06306508 |
100 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.06237770 |
101 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.05567849 |
102 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.05331967 |
103 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.05033459 |
104 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.05033459 |
105 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.05033459 |
106 | P300_19829295_ChIP-Seq_ESCs_Human | 1.03722606 |
107 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.03491009 |
108 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.02552051 |
109 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.01279668 |
110 | MAF_26560356_Chip-Seq_TH2_Human | 0.99987409 |
111 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.99906174 |
112 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.99276642 |
113 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.99249284 |
114 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.98848868 |
115 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.98188909 |
116 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.98060691 |
117 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.97783828 |
118 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.97677059 |
119 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97551950 |
120 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.97425176 |
121 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.97278617 |
122 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.97092627 |
123 | TP53_16413492_ChIP-PET_HCT116_Human | 0.97092415 |
124 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.96838895 |
125 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.96390563 |
126 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.96376165 |
127 | TCF4_23295773_ChIP-Seq_U87_Human | 0.96254789 |
128 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.96127163 |
129 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.95409342 |
130 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.95075614 |
131 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.94015193 |
132 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.93913707 |
133 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.92982194 |
134 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.92450902 |
135 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.91088197 |
136 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.90917184 |
137 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.90741458 |
138 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.90529163 |
139 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.90399147 |
140 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.89468051 |
141 | RXR_22108803_ChIP-Seq_LS180_Human | 0.89074077 |
142 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.85316614 |
143 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.84597847 |
144 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.84411698 |
145 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.84411698 |
146 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.83645526 |
147 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.83634629 |
148 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.83439840 |
149 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.82423518 |
150 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.82341549 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * MP0004859_abnormal_synaptic_plasticity | 7.28694853 |
2 | MP0003880_abnormal_central_pattern | 4.45817645 |
3 | * MP0003635_abnormal_synaptic_transmissio | 4.35808985 |
4 | MP0004270_analgesia | 3.98272264 |
5 | * MP0002063_abnormal_learning/memory/cond | 3.49679019 |
6 | MP0009745_abnormal_behavioral_response | 3.43487279 |
7 | MP0002822_catalepsy | 3.15239743 |
8 | MP0002064_seizures | 3.10420929 |
9 | MP0005423_abnormal_somatic_nervous | 2.98316279 |
10 | MP0002572_abnormal_emotion/affect_behav | 2.83081890 |
11 | MP0009046_muscle_twitch | 2.81343764 |
12 | MP0003705_abnormal_hypodermis_morpholog | 2.73441371 |
13 | MP0001968_abnormal_touch/_nociception | 2.73002234 |
14 | MP0001486_abnormal_startle_reflex | 2.60970579 |
15 | MP0002734_abnormal_mechanical_nocicepti | 2.53817297 |
16 | MP0002272_abnormal_nervous_system | 2.40115223 |
17 | MP0009780_abnormal_chondrocyte_physiolo | 2.37689023 |
18 | MP0001348_abnormal_lacrimal_gland | 2.15476099 |
19 | MP0001501_abnormal_sleep_pattern | 2.10252458 |
20 | MP0002249_abnormal_larynx_morphology | 2.03732907 |
21 | MP0004858_abnormal_nervous_system | 2.01886226 |
22 | MP0005076_abnormal_cell_differentiation | 2.01289737 |
23 | MP0009278_abnormal_bone_marrow | 1.97046118 |
24 | MP0000778_abnormal_nervous_system | 1.96718718 |
25 | MP0001849_ear_inflammation | 1.95052286 |
26 | MP0001440_abnormal_grooming_behavior | 1.94668312 |
27 | MP0002735_abnormal_chemical_nociception | 1.91106570 |
28 | MP0008569_lethality_at_weaning | 1.89891783 |
29 | * MP0004811_abnormal_neuron_physiology | 1.89761777 |
30 | MP0002733_abnormal_thermal_nociception | 1.89579964 |
31 | MP0002736_abnormal_nociception_after | 1.89257055 |
32 | MP0002909_abnormal_adrenal_gland | 1.84445269 |
33 | MP0001970_abnormal_pain_threshold | 1.82266254 |
34 | MP0002557_abnormal_social/conspecific_i | 1.80272297 |
35 | MP0002184_abnormal_innervation | 1.75266669 |
36 | MP0002067_abnormal_sensory_capabilities | 1.73104642 |
37 | MP0003329_amyloid_beta_deposits | 1.66564510 |
38 | MP0003879_abnormal_hair_cell | 1.65916607 |
39 | MP0004885_abnormal_endolymph | 1.64238309 |
40 | MP0004924_abnormal_behavior | 1.63206135 |
41 | MP0005386_behavior/neurological_phenoty | 1.63206135 |
42 | MP0000955_abnormal_spinal_cord | 1.62599145 |
43 | MP0005646_abnormal_pituitary_gland | 1.61966435 |
44 | MP0003787_abnormal_imprinting | 1.47086911 |
45 | * MP0002882_abnormal_neuron_morphology | 1.44904725 |
46 | MP0000566_synostosis | 1.44289896 |
47 | MP0009672_abnormal_birth_weight | 1.42165422 |
48 | * MP0002066_abnormal_motor_capabilities/c | 1.38569048 |
49 | MP0001984_abnormal_olfaction | 1.37884680 |
50 | MP0003633_abnormal_nervous_system | 1.36517978 |
51 | MP0002089_abnormal_postnatal_growth/wei | 1.34753652 |
52 | MP0000569_abnormal_digit_pigmentation | 1.34479767 |
53 | MP0005377_hearing/vestibular/ear_phenot | 1.33618760 |
54 | MP0003878_abnormal_ear_physiology | 1.33618760 |
55 | MP0003283_abnormal_digestive_organ | 1.27471852 |
56 | * MP0002152_abnormal_brain_morphology | 1.21498095 |
57 | MP0005645_abnormal_hypothalamus_physiol | 1.19806335 |
58 | MP0000428_abnormal_craniofacial_morphol | 1.19620958 |
59 | MP0003123_paternal_imprinting | 1.18043613 |
60 | MP0001502_abnormal_circadian_rhythm | 1.12965265 |
61 | MP0003631_nervous_system_phenotype | 1.12552423 |
62 | MP0008961_abnormal_basal_metabolism | 1.10937615 |
63 | MP0003122_maternal_imprinting | 1.10809653 |
64 | MP0003115_abnormal_respiratory_system | 1.10391810 |
65 | MP0001346_abnormal_lacrimal_gland | 1.07272028 |
66 | MP0003279_aneurysm | 1.07106407 |
67 | MP0006276_abnormal_autonomic_nervous | 1.05658287 |
68 | MP0003075_altered_response_to | 1.05372989 |
69 | MP0003938_abnormal_ear_development | 1.05038236 |
70 | MP0000537_abnormal_urethra_morphology | 1.02808043 |
71 | MP0002116_abnormal_craniofacial_bone | 1.00350643 |
72 | MP0001529_abnormal_vocalization | 0.99739862 |
73 | MP0001177_atelectasis | 0.99514633 |
74 | MP0002396_abnormal_hematopoietic_system | 0.98342085 |
75 | MP0003091_abnormal_cell_migration | 0.96499907 |
76 | MP0001905_abnormal_dopamine_level | 0.95739244 |
77 | MP0000751_myopathy | 0.94423333 |
78 | MP0000678_abnormal_parathyroid_gland | 0.94367003 |
79 | * MP0002069_abnormal_eating/drinking_beha | 0.93591202 |
80 | MP0001188_hyperpigmentation | 0.93316593 |
81 | MP0008872_abnormal_physiological_respon | 0.92862832 |
82 | MP0002081_perinatal_lethality | 0.92232193 |
83 | MP0008874_decreased_physiological_sensi | 0.91133404 |
84 | MP0010030_abnormal_orbit_morphology | 0.91034154 |
85 | MP0003942_abnormal_urinary_system | 0.89010047 |
86 | MP0000631_abnormal_neuroendocrine_gland | 0.87514159 |
87 | MP0000534_abnormal_ureter_morphology | 0.87261092 |
88 | MP0004142_abnormal_muscle_tone | 0.86690708 |
89 | MP0003385_abnormal_body_wall | 0.86238396 |
90 | MP0005394_taste/olfaction_phenotype | 0.86074463 |
91 | MP0005499_abnormal_olfactory_system | 0.86074463 |
92 | MP0004085_abnormal_heartbeat | 0.85402941 |
93 | MP0005623_abnormal_meninges_morphology | 0.82432339 |
94 | MP0003119_abnormal_digestive_system | 0.82246350 |
95 | MP0004145_abnormal_muscle_electrophysio | 0.82219663 |
96 | MP0002229_neurodegeneration | 0.81712296 |
97 | MP0004130_abnormal_muscle_cell | 0.81427523 |
98 | MP0009703_decreased_birth_body | 0.81377420 |
99 | MP0003634_abnormal_glial_cell | 0.81008907 |
100 | MP0005503_abnormal_tendon_morphology | 0.80978317 |
101 | * MP0010768_mortality/aging | 0.77470625 |
102 | MP0005409_darkened_coat_color | 0.76870884 |
103 | MP0003690_abnormal_glial_cell | 0.76610397 |
104 | MP0003632_abnormal_nervous_system | 0.75379875 |
105 | MP0005167_abnormal_blood-brain_barrier | 0.75155953 |
106 | MP0003861_abnormal_nervous_system | 0.74567853 |
107 | MP0004133_heterotaxia | 0.72914025 |
108 | MP0002009_preneoplasia | 0.72697467 |
109 | MP0002932_abnormal_joint_morphology | 0.72587902 |
110 | MP0000579_abnormal_nail_morphology | 0.72118474 |
111 | MP0001963_abnormal_hearing_physiology | 0.72003484 |
112 | MP0005551_abnormal_eye_electrophysiolog | 0.71827682 |
113 | MP0002090_abnormal_vision | 0.70789584 |
114 | MP0005187_abnormal_penis_morphology | 0.70578683 |
115 | MP0004185_abnormal_adipocyte_glucose | 0.70417956 |
116 | MP0002752_abnormal_somatic_nervous | 0.69571110 |
117 | MP0004233_abnormal_muscle_weight | 0.69409053 |
118 | MP0000013_abnormal_adipose_tissue | 0.69406235 |
119 | MP0000432_abnormal_head_morphology | 0.69343406 |
120 | MP0005535_abnormal_body_temperature | 0.69063263 |
121 | MP0000733_abnormal_muscle_development | 0.68987804 |
122 | MP0002114_abnormal_axial_skeleton | 0.68049871 |
123 | MP0003137_abnormal_impulse_conducting | 0.67458671 |
124 | MP0002925_abnormal_cardiovascular_devel | 0.67198552 |
125 | MP0000920_abnormal_myelination | 0.67154411 |
126 | MP0004742_abnormal_vestibular_system | 0.67084829 |
127 | MP0002234_abnormal_pharynx_morphology | 0.66073596 |
128 | MP0004510_myositis | 0.65357503 |
129 | MP0003172_abnormal_lysosome_physiology | 0.64549477 |
130 | MP0002653_abnormal_ependyma_morphology | 0.61525821 |
131 | MP0001299_abnormal_eye_distance/ | 0.61173421 |
132 | MP0000604_amyloidosis | 0.60635556 |
133 | MP0001485_abnormal_pinna_reflex | 0.58289044 |
134 | MP0004484_altered_response_of | 0.57920501 |
135 | MP0001943_abnormal_respiration | 0.57525226 |
136 | MP0010386_abnormal_urinary_bladder | 0.57502729 |
137 | * MP0010769_abnormal_survival | 0.57046625 |
138 | MP0001664_abnormal_digestion | 0.55806876 |
139 | MP0004215_abnormal_myocardial_fiber | 0.55025578 |
140 | * MP0002082_postnatal_lethality | 0.53519411 |
141 | * MP0010770_preweaning_lethality | 0.53519411 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Myokymia (HP:0002411) | 7.26169163 |
2 | Focal motor seizures (HP:0011153) | 7.09792079 |
3 | Focal seizures (HP:0007359) | 5.61201610 |
4 | Visual hallucinations (HP:0002367) | 4.98689832 |
5 | Progressive cerebellar ataxia (HP:0002073) | 4.11305772 |
6 | Action tremor (HP:0002345) | 3.82588680 |
7 | * Epileptic encephalopathy (HP:0200134) | 3.75824520 |
8 | Febrile seizures (HP:0002373) | 3.73898657 |
9 | Broad-based gait (HP:0002136) | 3.59953463 |
10 | Atonic seizures (HP:0010819) | 3.58443425 |
11 | Absence seizures (HP:0002121) | 3.57005049 |
12 | Poor eye contact (HP:0000817) | 3.55161704 |
13 | Generalized tonic-clonic seizures (HP:0002069) | 3.52364909 |
14 | Papilledema (HP:0001085) | 3.52005147 |
15 | Supranuclear gaze palsy (HP:0000605) | 3.51222494 |
16 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.50838666 |
17 | Ankle clonus (HP:0011448) | 3.50344621 |
18 | Dialeptic seizures (HP:0011146) | 3.28142342 |
19 | Turricephaly (HP:0000262) | 3.28018319 |
20 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.27738669 |
21 | Depression (HP:0000716) | 3.24957640 |
22 | Shallow orbits (HP:0000586) | 3.21199921 |
23 | Impaired social interactions (HP:0000735) | 3.19219098 |
24 | Abnormal social behavior (HP:0012433) | 3.19219098 |
25 | Genetic anticipation (HP:0003743) | 3.16254080 |
26 | Gaze-evoked nystagmus (HP:0000640) | 3.13662405 |
27 | Mutism (HP:0002300) | 3.11599721 |
28 | Abnormality of the lower motor neuron (HP:0002366) | 3.06544680 |
29 | Bronchomalacia (HP:0002780) | 3.03917192 |
30 | Dysdiadochokinesis (HP:0002075) | 3.03150669 |
31 | Postural instability (HP:0002172) | 2.98494481 |
32 | Dysmetria (HP:0001310) | 2.91276376 |
33 | Abnormality of the fingertips (HP:0001211) | 2.90963058 |
34 | Broad metatarsal (HP:0001783) | 2.87290155 |
35 | Anxiety (HP:0000739) | 2.86747839 |
36 | Amblyopia (HP:0000646) | 2.86454084 |
37 | Hyperventilation (HP:0002883) | 2.76585647 |
38 | Megalencephaly (HP:0001355) | 2.76397972 |
39 | Abnormal eating behavior (HP:0100738) | 2.74170447 |
40 | Impaired smooth pursuit (HP:0007772) | 2.73173762 |
41 | Drooling (HP:0002307) | 2.72997747 |
42 | Excessive salivation (HP:0003781) | 2.72997747 |
43 | Stereotypic behavior (HP:0000733) | 2.70614296 |
44 | Obstructive sleep apnea (HP:0002870) | 2.69473979 |
45 | Urinary urgency (HP:0000012) | 2.66301150 |
46 | Truncal ataxia (HP:0002078) | 2.66106153 |
47 | Hemiparesis (HP:0001269) | 2.63605596 |
48 | Annular pancreas (HP:0001734) | 2.61033231 |
49 | Broad face (HP:0000283) | 2.54577697 |
50 | Pointed chin (HP:0000307) | 2.50154478 |
51 | Hemiplegia (HP:0002301) | 2.49561961 |
52 | Spastic gait (HP:0002064) | 2.48133552 |
53 | Insomnia (HP:0100785) | 2.44561187 |
54 | Intention tremor (HP:0002080) | 2.43185481 |
55 | Epileptiform EEG discharges (HP:0011182) | 2.41477649 |
56 | Abnormality of binocular vision (HP:0011514) | 2.39876549 |
57 | Diplopia (HP:0000651) | 2.39876549 |
58 | Cerebral inclusion bodies (HP:0100314) | 2.39072213 |
59 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.38325813 |
60 | Bradykinesia (HP:0002067) | 2.37693830 |
61 | Trigonocephaly (HP:0000243) | 2.36974509 |
62 | Impaired vibratory sensation (HP:0002495) | 2.35901981 |
63 | Urethral obstruction (HP:0000796) | 2.35640519 |
64 | Neurofibrillary tangles (HP:0002185) | 2.30833504 |
65 | EEG with generalized epileptiform discharges (HP:0011198) | 2.29845996 |
66 | Dysmetric saccades (HP:0000641) | 2.24769582 |
67 | Absent speech (HP:0001344) | 2.23221671 |
68 | Hypsarrhythmia (HP:0002521) | 2.22998924 |
69 | Ventricular fibrillation (HP:0001663) | 2.22145707 |
70 | Abnormality of the aortic arch (HP:0012303) | 2.21833113 |
71 | * Torticollis (HP:0000473) | 2.20163860 |
72 | Ankyloglossia (HP:0010296) | 2.17771411 |
73 | Insidious onset (HP:0003587) | 2.17149414 |
74 | Termporal pattern (HP:0011008) | 2.17149414 |
75 | Amyotrophic lateral sclerosis (HP:0007354) | 2.16635441 |
76 | Abnormality of the corticospinal tract (HP:0002492) | 2.16612493 |
77 | Lower limb muscle weakness (HP:0007340) | 2.16388822 |
78 | Scanning speech (HP:0002168) | 2.15669261 |
79 | Lower limb amyotrophy (HP:0007210) | 2.15381964 |
80 | * Focal dystonia (HP:0004373) | 2.13861203 |
81 | Progressive inability to walk (HP:0002505) | 2.12140081 |
82 | Arnold-Chiari malformation (HP:0002308) | 2.08830603 |
83 | Cerebral aneurysm (HP:0004944) | 2.07699888 |
84 | Tracheomalacia (HP:0002779) | 2.00147743 |
85 | Inappropriate behavior (HP:0000719) | 1.99806256 |
86 | Bundle branch block (HP:0011710) | 1.99656112 |
87 | Peripheral hypomyelination (HP:0007182) | 1.98923034 |
88 | Broad thumb (HP:0011304) | 1.98568335 |
89 | Vertebral arch anomaly (HP:0008438) | 1.98046265 |
90 | Long eyelashes (HP:0000527) | 1.97733568 |
91 | Broad palm (HP:0001169) | 1.97542122 |
92 | Agitation (HP:0000713) | 1.96885806 |
93 | Status epilepticus (HP:0002133) | 1.96879983 |
94 | Ulnar bowing (HP:0003031) | 1.95712774 |
95 | Distal upper limb amyotrophy (HP:0007149) | 1.95459969 |
96 | Upper limb amyotrophy (HP:0009129) | 1.95459969 |
97 | Disproportionate tall stature (HP:0001519) | 1.94993644 |
98 | Bowel incontinence (HP:0002607) | 1.94435601 |
99 | Fetal akinesia sequence (HP:0001989) | 1.93905669 |
100 | Narrow palate (HP:0000189) | 1.93242134 |
101 | Limb dystonia (HP:0002451) | 1.91953774 |
102 | Precocious puberty (HP:0000826) | 1.90933856 |
103 | Thin ribs (HP:0000883) | 1.90866924 |
104 | Long palpebral fissure (HP:0000637) | 1.90697066 |
105 | Broad phalanges of the hand (HP:0009768) | 1.90229456 |
106 | Generalized myoclonic seizures (HP:0002123) | 1.89767529 |
107 | Broad finger (HP:0001500) | 1.89002354 |
108 | Incomplete penetrance (HP:0003829) | 1.88535090 |
109 | Atelectasis (HP:0100750) | 1.88289879 |
110 | Apathy (HP:0000741) | 1.88077576 |
111 | Metaphyseal cupping (HP:0003021) | 1.85897591 |
112 | Clonus (HP:0002169) | 1.85886456 |
113 | Abnormal EKG (HP:0003115) | 1.83506897 |
114 | Renovascular hypertension (HP:0100817) | 1.83221750 |
115 | Supernumerary ribs (HP:0005815) | 1.82157974 |
116 | Lower limb asymmetry (HP:0100559) | 1.81791379 |
117 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.80530112 |
118 | Inability to walk (HP:0002540) | 1.79844471 |
119 | Protrusio acetabuli (HP:0003179) | 1.79608946 |
120 | Spinal canal stenosis (HP:0003416) | 1.79232780 |
121 | Obsessive-compulsive behavior (HP:0000722) | 1.79166796 |
122 | Intellectual disability, profound (HP:0002187) | 1.78225959 |
123 | Abnormality of salivation (HP:0100755) | 1.77314600 |
124 | Deep palmar crease (HP:0006191) | 1.77174135 |
125 | Gait ataxia (HP:0002066) | 1.76947292 |
126 | Overriding aorta (HP:0002623) | 1.76854198 |
127 | Polyphagia (HP:0002591) | 1.76096132 |
128 | Aqueductal stenosis (HP:0002410) | 1.75056964 |
129 | Neuronal loss in central nervous system (HP:0002529) | 1.74426788 |
130 | Aplasia involving bones of the extremities (HP:0009825) | 1.73003501 |
131 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.73003501 |
132 | Aplasia of the phalanges of the hand (HP:0009802) | 1.73003501 |
133 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.73002297 |
134 | Short 4th metacarpal (HP:0010044) | 1.73002297 |
135 | Macroorchidism (HP:0000053) | 1.72909020 |
136 | Choanal stenosis (HP:0000452) | 1.72761857 |
137 | Rapidly progressive (HP:0003678) | 1.71712976 |
138 | Broad long bones (HP:0005622) | 1.71098793 |
139 | Hyperacusis (HP:0010780) | 1.70336093 |
140 | Hypoventilation (HP:0002791) | 1.70316042 |
141 | Hand muscle atrophy (HP:0009130) | 1.69922911 |
142 | Abnormality of the columella (HP:0009929) | 1.69541601 |
143 | Genu recurvatum (HP:0002816) | 1.69434582 |
144 | Broad phalanx (HP:0006009) | 1.69374561 |
145 | Sleep apnea (HP:0010535) | 1.69034562 |
146 | * Craniofacial dystonia (HP:0012179) | 1.69004358 |
147 | Mild short stature (HP:0003502) | 1.68531681 |
148 | Deeply set eye (HP:0000490) | 1.68248360 |
149 | Resting tremor (HP:0002322) | 1.68245234 |
150 | Abnormal large intestine physiology (HP:0012700) | 1.66954211 |
151 | Vitreoretinal degeneration (HP:0000655) | 1.66082029 |
152 | Bell-shaped thorax (HP:0001591) | 1.66038270 |
153 | Neoplasm of the heart (HP:0100544) | 1.66019104 |
154 | Spina bifida occulta (HP:0003298) | 1.64827973 |
155 | Heterotopia (HP:0002282) | 1.64773433 |
156 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.62652822 |
157 | Dislocated radial head (HP:0003083) | 1.62565723 |
158 | Elfin facies (HP:0004428) | 1.62114029 |
159 | Bowel diverticulosis (HP:0005222) | 1.60411992 |
160 | Mitral valve prolapse (HP:0001634) | 1.60254525 |
161 | Mitral regurgitation (HP:0001653) | 1.59938222 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA4 | 4.71068579 |
2 | NTRK3 | 4.42866040 |
3 | MAP3K9 | 3.91377219 |
4 | MARK1 | 3.52830820 |
5 | CDK12 | 3.42862087 |
6 | TRIB3 | 3.20514723 |
7 | DAPK2 | 2.78799785 |
8 | PRKD3 | 2.76269993 |
9 | MINK1 | 2.69148532 |
10 | MAP3K4 | 2.67523456 |
11 | MAP3K10 | 2.66510211 |
12 | PAK6 | 2.49254447 |
13 | EEF2K | 2.32822951 |
14 | NTRK2 | 2.26539949 |
15 | KSR2 | 2.19547528 |
16 | SMG1 | 2.13084303 |
17 | CAMKK1 | 2.11255510 |
18 | MAP2K7 | 2.10245637 |
19 | SIK1 | 1.82889914 |
20 | NTRK1 | 1.81955916 |
21 | KSR1 | 1.81448987 |
22 | DAPK1 | 1.78455075 |
23 | FGFR4 | 1.71827317 |
24 | MAPK15 | 1.67381276 |
25 | CDK5 | 1.62877692 |
26 | SIK2 | 1.59188222 |
27 | MAP2K4 | 1.57015793 |
28 | BRD4 | 1.55438913 |
29 | CAMK1D | 1.48275190 |
30 | TNIK | 1.46787272 |
31 | STK38 | 1.46724591 |
32 | RIPK4 | 1.43225833 |
33 | TAOK1 | 1.42885522 |
34 | TYRO3 | 1.36574462 |
35 | PRPF4B | 1.33063955 |
36 | FES | 1.25436473 |
37 | MAPK13 | 1.25383285 |
38 | MAP3K2 | 1.21685772 |
39 | LATS2 | 1.21028883 |
40 | PLK2 | 1.20658094 |
41 | PNCK | 1.19409928 |
42 | PRKCG | 1.18052525 |
43 | UHMK1 | 1.14479955 |
44 | GRK5 | 1.10747455 |
45 | MAP3K12 | 1.10524047 |
46 | CASK | 1.10111933 |
47 | MTOR | 1.08533982 |
48 | CAMK1 | 1.07831919 |
49 | STK11 | 1.04171299 |
50 | CDK19 | 1.03033124 |
51 | PHKG2 | 1.02639715 |
52 | PHKG1 | 1.02639715 |
53 | ALK | 0.95715695 |
54 | PRKCH | 0.93370386 |
55 | CDK18 | 0.93016073 |
56 | CDK15 | 0.92310756 |
57 | MARK2 | 0.91824223 |
58 | MAP3K13 | 0.90523827 |
59 | HIPK2 | 0.88709233 |
60 | BMX | 0.88606544 |
61 | RAF1 | 0.87709145 |
62 | ARAF | 0.87623049 |
63 | RIPK1 | 0.87014541 |
64 | CDK14 | 0.86429866 |
65 | CAMKK2 | 0.86210539 |
66 | RET | 0.84792989 |
67 | CDK11A | 0.81323600 |
68 | PAK3 | 0.80731358 |
69 | PKN2 | 0.80274847 |
70 | PTK2B | 0.79778546 |
71 | FGFR3 | 0.79010206 |
72 | * CAMK2A | 0.78290411 |
73 | MAPK12 | 0.77024190 |
74 | CAMK1G | 0.75755892 |
75 | WNK1 | 0.75552353 |
76 | SGK223 | 0.72556385 |
77 | SGK494 | 0.72556385 |
78 | SGK1 | 0.71359714 |
79 | CAMK2B | 0.70153913 |
80 | MAP4K1 | 0.70077516 |
81 | ERN1 | 0.69810388 |
82 | DYRK1A | 0.68370681 |
83 | PDK1 | 0.68344509 |
84 | SIK3 | 0.68149332 |
85 | SGK3 | 0.67344576 |
86 | DMPK | 0.66863804 |
87 | CSNK1G2 | 0.66384158 |
88 | MAPK7 | 0.65053375 |
89 | PDGFRB | 0.63710228 |
90 | SGK2 | 0.63505745 |
91 | PTK6 | 0.63427747 |
92 | LMTK2 | 0.62232925 |
93 | RPS6KL1 | 0.60765953 |
94 | RPS6KC1 | 0.60765953 |
95 | CDC42BPA | 0.60079776 |
96 | PASK | 0.58197503 |
97 | PDPK1 | 0.57715927 |
98 | PRKCZ | 0.57004029 |
99 | MAP3K7 | 0.56725908 |
100 | ICK | 0.56093895 |
101 | CAMK4 | 0.56075718 |
102 | MAP3K1 | 0.55517237 |
103 | RPS6KA3 | 0.54678338 |
104 | FYN | 0.50976508 |
105 | DYRK1B | 0.50282369 |
106 | ERBB2 | 0.50017582 |
107 | DDR2 | 0.50009033 |
108 | PINK1 | 0.48879401 |
109 | EPHB1 | 0.48690442 |
110 | MAPK10 | 0.46991459 |
111 | NEK6 | 0.46703513 |
112 | BRSK1 | 0.46384648 |
113 | GSK3B | 0.45131895 |
114 | TTN | 0.44386482 |
115 | RPS6KA6 | 0.42596482 |
116 | PDGFRA | 0.42203251 |
117 | CDK4 | 0.41774301 |
118 | MAP2K2 | 0.41501991 |
119 | DAPK3 | 0.41216185 |
120 | SCYL2 | 0.41172499 |
121 | RPS6KA2 | 0.41156506 |
122 | PRKD2 | 0.39367128 |
123 | TNK2 | 0.38768229 |
124 | BMPR2 | 0.37845276 |
125 | ZAP70 | 0.37409812 |
126 | PRKCE | 0.36859423 |
127 | PTK2 | 0.35575847 |
128 | NEK1 | 0.35480671 |
129 | CDK2 | 0.34064352 |
130 | PAK2 | 0.33176271 |
131 | FGFR2 | 0.32485498 |
132 | FER | 0.31807483 |
133 | PRKCB | 0.31764725 |
134 | MAP2K1 | 0.31506604 |
135 | FGR | 0.31345903 |
136 | MAP3K6 | 0.30968083 |
137 | MAPK8 | 0.29784955 |
138 | OXSR1 | 0.29654154 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.36364398 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.90532077 |
3 | Olfactory transduction_Homo sapiens_hsa04740 | 2.80950106 |
4 | Circadian entrainment_Homo sapiens_hsa04713 | 2.74978569 |
5 | Long-term potentiation_Homo sapiens_hsa04720 | 2.71764892 |
6 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.60132049 |
7 | GABAergic synapse_Homo sapiens_hsa04727 | 2.52373562 |
8 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.50493984 |
9 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.45606141 |
10 | Morphine addiction_Homo sapiens_hsa05032 | 2.38970270 |
11 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.23119875 |
12 | Salivary secretion_Homo sapiens_hsa04970 | 2.16075564 |
13 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.14638011 |
14 | Insulin secretion_Homo sapiens_hsa04911 | 2.04771485 |
15 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.97270511 |
16 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.96923909 |
17 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.94306252 |
18 | Cocaine addiction_Homo sapiens_hsa05030 | 1.74459449 |
19 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.74017195 |
20 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.72969905 |
21 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.71732273 |
22 | Renin secretion_Homo sapiens_hsa04924 | 1.65839807 |
23 | Long-term depression_Homo sapiens_hsa04730 | 1.60375954 |
24 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.57657984 |
25 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.51647525 |
26 | Taste transduction_Homo sapiens_hsa04742 | 1.48872733 |
27 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.47067259 |
28 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.43975107 |
29 | Gap junction_Homo sapiens_hsa04540 | 1.39940671 |
30 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.38482331 |
31 | Glioma_Homo sapiens_hsa05214 | 1.37045445 |
32 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.35943525 |
33 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.33948746 |
34 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.33877649 |
35 | Axon guidance_Homo sapiens_hsa04360 | 1.27865285 |
36 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.26833756 |
37 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.25621371 |
38 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.25172621 |
39 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.24827207 |
40 | Melanogenesis_Homo sapiens_hsa04916 | 1.18160981 |
41 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.16047779 |
42 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.15992740 |
43 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.10416099 |
44 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.10168164 |
45 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.02449449 |
46 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.01904119 |
47 | Adherens junction_Homo sapiens_hsa04520 | 1.01532344 |
48 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.99736314 |
49 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.96702882 |
50 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.94754988 |
51 | Thyroid cancer_Homo sapiens_hsa05216 | 0.94575307 |
52 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.94023931 |
53 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.93891182 |
54 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.91857987 |
55 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.90713593 |
56 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.90431923 |
57 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.89736695 |
58 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.85880652 |
59 | Prostate cancer_Homo sapiens_hsa05215 | 0.84657639 |
60 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.84299612 |
61 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.84016050 |
62 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.83509055 |
63 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.82505110 |
64 | Lysine degradation_Homo sapiens_hsa00310 | 0.81705815 |
65 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.80836252 |
66 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.79898824 |
67 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.79790218 |
68 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.79602476 |
69 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.79028811 |
70 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.78890147 |
71 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.78252616 |
72 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.77529113 |
73 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.76892559 |
74 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.75850726 |
75 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.75806567 |
76 | Focal adhesion_Homo sapiens_hsa04510 | 0.74935970 |
77 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.74912863 |
78 | Phototransduction_Homo sapiens_hsa04744 | 0.72619134 |
79 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.72549439 |
80 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.71725987 |
81 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.71466550 |
82 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.69947839 |
83 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.69126697 |
84 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.69036016 |
85 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.66909304 |
86 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.66276729 |
87 | Endometrial cancer_Homo sapiens_hsa05213 | 0.65724466 |
88 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.64953901 |
89 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.64487084 |
90 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.62891848 |
91 | * Ras signaling pathway_Homo sapiens_hsa04014 | 0.61322656 |
92 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.61186500 |
93 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.61165284 |
94 | Amoebiasis_Homo sapiens_hsa05146 | 0.60487480 |
95 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.60467243 |
96 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.58976146 |
97 | Pathways in cancer_Homo sapiens_hsa05200 | 0.56683821 |
98 | Endocytosis_Homo sapiens_hsa04144 | 0.55902286 |
99 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.55412014 |
100 | Alcoholism_Homo sapiens_hsa05034 | 0.55218872 |
101 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.52936010 |
102 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.52900006 |
103 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.52891795 |
104 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.52636334 |
105 | Bile secretion_Homo sapiens_hsa04976 | 0.49096063 |
106 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.47350039 |
107 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.46987072 |
108 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.46440929 |
109 | Circadian rhythm_Homo sapiens_hsa04710 | 0.45826295 |
110 | Prion diseases_Homo sapiens_hsa05020 | 0.44402964 |
111 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.44027130 |
112 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.43726299 |
113 | Colorectal cancer_Homo sapiens_hsa05210 | 0.42188870 |
114 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.41446322 |
115 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.39867542 |
116 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.39476245 |
117 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.38278561 |
118 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.37860071 |
119 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.35222127 |
120 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.35096984 |
121 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.33649704 |
122 | Platelet activation_Homo sapiens_hsa04611 | 0.31207646 |
123 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.29791342 |
124 | Tight junction_Homo sapiens_hsa04530 | 0.28967399 |
125 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.28560241 |