Rank | Gene Set | Z-score |
---|---|---|
1 | muscle filament sliding (GO:0030049) | 9.01084570 |
2 | actin-myosin filament sliding (GO:0033275) | 9.01084570 |
3 | regulation of skeletal muscle contraction (GO:0014819) | 7.99670878 |
4 | actin-mediated cell contraction (GO:0070252) | 7.51981714 |
5 | sarcomere organization (GO:0045214) | 6.90158920 |
6 | plasma membrane repair (GO:0001778) | 6.69650469 |
7 | skeletal muscle contraction (GO:0003009) | 6.26588046 |
8 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 6.12164567 |
9 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 6.09052873 |
10 | myofibril assembly (GO:0030239) | 6.07414478 |
11 | actin filament-based movement (GO:0030048) | 5.83207215 |
12 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 5.71968484 |
13 | cardiac myofibril assembly (GO:0055003) | 5.59698510 |
14 | skeletal muscle adaptation (GO:0043501) | 5.45436763 |
15 | carnitine shuttle (GO:0006853) | 5.33065944 |
16 | striated muscle contraction (GO:0006941) | 5.20763801 |
17 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 5.18715545 |
18 | production of molecular mediator involved in inflammatory response (GO:0002532) | 5.06516181 |
19 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 4.97139622 |
20 | actomyosin structure organization (GO:0031032) | 4.91190881 |
21 | fatty acid transmembrane transport (GO:1902001) | 4.83839647 |
22 | cardiac muscle contraction (GO:0060048) | 4.70701146 |
23 | creatine metabolic process (GO:0006600) | 4.61929129 |
24 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 4.55139774 |
25 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 4.53051892 |
26 | regulation of translation, ncRNA-mediated (GO:0045974) | 4.53051892 |
27 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 4.53051892 |
28 | regulation of relaxation of muscle (GO:1901077) | 4.52807284 |
29 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 4.51664626 |
30 | regulation of cell communication by electrical coupling (GO:0010649) | 4.50589624 |
31 | muscle contraction (GO:0006936) | 4.46893076 |
32 | cardiac muscle cell development (GO:0055013) | 4.42884713 |
33 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 4.31567423 |
34 | skeletal muscle tissue development (GO:0007519) | 4.30485555 |
35 | striated muscle atrophy (GO:0014891) | 4.22574838 |
36 | tricarboxylic acid cycle (GO:0006099) | 4.20448228 |
37 | cardiac cell development (GO:0055006) | 4.18603550 |
38 | muscle system process (GO:0003012) | 4.08325839 |
39 | response to inactivity (GO:0014854) | 4.07741363 |
40 | regulation of sequestering of triglyceride (GO:0010889) | 4.05122395 |
41 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 4.03918792 |
42 | skeletal muscle fiber development (GO:0048741) | 4.03834337 |
43 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 4.03785389 |
44 | carnitine transmembrane transport (GO:1902603) | 3.99703934 |
45 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 3.85151633 |
46 | regulation of actin filament-based movement (GO:1903115) | 3.84880615 |
47 | motile cilium assembly (GO:0044458) | 3.79207970 |
48 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.78735815 |
49 | striated muscle adaptation (GO:0014888) | 3.77555896 |
50 | muscle fiber development (GO:0048747) | 3.77078215 |
51 | glycogen catabolic process (GO:0005980) | 3.67939608 |
52 | muscle cell fate commitment (GO:0042693) | 3.65830690 |
53 | regulation of striated muscle contraction (GO:0006942) | 3.63766737 |
54 | carnitine transport (GO:0015879) | 3.60181006 |
55 | amino-acid betaine transport (GO:0015838) | 3.60181006 |
56 | cell migration involved in heart development (GO:0060973) | 3.58693681 |
57 | muscle atrophy (GO:0014889) | 3.58414747 |
58 | ventricular cardiac muscle cell action potential (GO:0086005) | 3.56147493 |
59 | muscle tissue morphogenesis (GO:0060415) | 3.52256640 |
60 | cardiac muscle hypertrophy (GO:0003300) | 3.49122531 |
61 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 3.47938685 |
62 | cardiac muscle tissue morphogenesis (GO:0055008) | 3.47750836 |
63 | myotube cell development (GO:0014904) | 3.47164628 |
64 | striated muscle hypertrophy (GO:0014897) | 3.46207865 |
65 | regulation of cofactor metabolic process (GO:0051193) | 3.44398721 |
66 | regulation of coenzyme metabolic process (GO:0051196) | 3.44398721 |
67 | glucan catabolic process (GO:0009251) | 3.44156456 |
68 | striated muscle cell development (GO:0055002) | 3.40547562 |
69 | glycogen biosynthetic process (GO:0005978) | 3.35794800 |
70 | glucan biosynthetic process (GO:0009250) | 3.35794800 |
71 | myoblast fusion (GO:0007520) | 3.34412499 |
72 | striated muscle tissue development (GO:0014706) | 3.29293513 |
73 | nerve growth factor signaling pathway (GO:0038180) | 3.28675023 |
74 | skeletal muscle tissue regeneration (GO:0043403) | 3.27258263 |
75 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.25295357 |
76 | response to muscle activity (GO:0014850) | 3.23763893 |
77 | positive regulation of myotube differentiation (GO:0010831) | 3.23741421 |
78 | positive regulation of myoblast differentiation (GO:0045663) | 3.23722249 |
79 | macroautophagy (GO:0016236) | 3.20177590 |
80 | regulation of membrane repolarization (GO:0060306) | 3.20041916 |
81 | cellular polysaccharide catabolic process (GO:0044247) | 3.18868565 |
82 | regulation of muscle adaptation (GO:0043502) | 3.18840004 |
83 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.18743951 |
84 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 3.17514593 |
85 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.17374289 |
86 | muscle adaptation (GO:0043500) | 3.16098367 |
87 | cytidine metabolic process (GO:0046087) | 3.15488336 |
88 | cytidine catabolic process (GO:0006216) | 3.15488336 |
89 | cytidine deamination (GO:0009972) | 3.15488336 |
90 | heart contraction (GO:0060047) | 3.15444228 |
91 | heart process (GO:0003015) | 3.15444228 |
92 | positive regulation of cation channel activity (GO:2001259) | 3.13989769 |
93 | adult heart development (GO:0007512) | 3.12169646 |
94 | regulation of skeletal muscle cell differentiation (GO:2001014) | 3.11407751 |
95 | regulation of p38MAPK cascade (GO:1900744) | 3.11229016 |
96 | 2-oxoglutarate metabolic process (GO:0006103) | 3.09213886 |
97 | muscle tissue development (GO:0060537) | 3.08658351 |
98 | relaxation of muscle (GO:0090075) | 3.08386611 |
99 | regulation of sarcomere organization (GO:0060297) | 3.08031046 |
100 | valine metabolic process (GO:0006573) | 3.06564157 |
101 | muscle hypertrophy (GO:0014896) | 3.06434968 |
102 | lipid particle organization (GO:0034389) | 3.05001934 |
103 | regulation of myoblast differentiation (GO:0045661) | 3.02159793 |
104 | heart trabecula formation (GO:0060347) | 3.01799226 |
105 | regulation of muscle contraction (GO:0006937) | 3.00429544 |
106 | polysaccharide catabolic process (GO:0000272) | 2.99517210 |
107 | intracellular lipid transport (GO:0032365) | 2.93332485 |
108 | entrainment of circadian clock by photoperiod (GO:0043153) | 2.93125290 |
109 | NADH metabolic process (GO:0006734) | 2.92998832 |
110 | regulation of fatty acid oxidation (GO:0046320) | 2.92777326 |
111 | syncytium formation by plasma membrane fusion (GO:0000768) | 2.92146045 |
112 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 2.91182202 |
113 | muscle hypertrophy in response to stress (GO:0003299) | 2.91182202 |
114 | cardiac muscle adaptation (GO:0014887) | 2.91182202 |
115 | muscle cell development (GO:0055001) | 2.91081778 |
116 | regulation of muscle system process (GO:0090257) | 2.90064184 |
117 | regulation of calcium ion transmembrane transport (GO:1903169) | 2.89346932 |
118 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 2.89346932 |
119 | negative regulation of muscle hypertrophy (GO:0014741) | 2.88186157 |
120 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 2.87978849 |
121 | oxaloacetate metabolic process (GO:0006107) | 2.86250562 |
122 | muscle cell cellular homeostasis (GO:0046716) | 2.85473175 |
123 | negative regulation of protein localization to cell surface (GO:2000009) | 2.82900489 |
124 | regulation of the force of heart contraction (GO:0002026) | 2.82855640 |
125 | muscle organ development (GO:0007517) | 2.82621331 |
126 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 2.80974265 |
127 | muscle structure development (GO:0061061) | 2.80471900 |
128 | response to caffeine (GO:0031000) | 2.74736569 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 6.45686148 |
2 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 3.36668025 |
3 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.96520319 |
4 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 2.74635733 |
5 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 2.74635733 |
6 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.72743078 |
7 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.69986912 |
8 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.66523455 |
9 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.55446596 |
10 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.44381534 |
11 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.39046021 |
12 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.20299461 |
13 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.12597856 |
14 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 2.10335471 |
15 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.01998766 |
16 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.97171010 |
17 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.89999203 |
18 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.88014939 |
19 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.85217369 |
20 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.83546256 |
21 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.82923422 |
22 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.75756876 |
23 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.74840106 |
24 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.74776367 |
25 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.71577094 |
26 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.64757290 |
27 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.63147850 |
28 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.58369666 |
29 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.56553524 |
30 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.56237569 |
31 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.52109138 |
32 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.51041447 |
33 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.48812373 |
34 | CJUN_26792858_Chip-Seq_BT549_Human | 1.48097201 |
35 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.48047577 |
36 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.43549841 |
37 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.43509663 |
38 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.41681836 |
39 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.41518682 |
40 | GATA1_22025678_ChIP-Seq_K562_Human | 1.41433782 |
41 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.35935367 |
42 | VDR_22108803_ChIP-Seq_LS180_Human | 1.34777868 |
43 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.33652245 |
44 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.32601048 |
45 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.31838159 |
46 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.29292581 |
47 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.28860367 |
48 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.27908431 |
49 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.27579617 |
50 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.25206879 |
51 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.23937300 |
52 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.23899612 |
53 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.23439842 |
54 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.23057152 |
55 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.19606958 |
56 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.19534831 |
57 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.19475456 |
58 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.19097680 |
59 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.15492058 |
60 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.14120011 |
61 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.14043257 |
62 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.13259943 |
63 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.13096186 |
64 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 1.13060349 |
65 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.12961038 |
66 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.12137219 |
67 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.11942321 |
68 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.10500010 |
69 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.08655453 |
70 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.08127070 |
71 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.05209296 |
72 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.04897001 |
73 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.04620655 |
74 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.04355108 |
75 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.04041292 |
76 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.04030522 |
77 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.03337255 |
78 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.03337255 |
79 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.03153551 |
80 | TP53_16413492_ChIP-PET_HCT116_Human | 1.02866556 |
81 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.02853613 |
82 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.02683508 |
83 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.02335250 |
84 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.02227680 |
85 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.02150468 |
86 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.01128019 |
87 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.01116964 |
88 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.00938624 |
89 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.00870253 |
90 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.00865227 |
91 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.00136775 |
92 | KDM2B_26808549_Chip-Seq_K562_Human | 0.99867937 |
93 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.99699193 |
94 | * NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.99627972 |
95 | * NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.99627972 |
96 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.98499520 |
97 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.97849675 |
98 | * ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.97670633 |
99 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.97346268 |
100 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.96340534 |
101 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.96336113 |
102 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.96237484 |
103 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.95987726 |
104 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.95468650 |
105 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.94361832 |
106 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.94160576 |
107 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.94151655 |
108 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.93921489 |
109 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.93844689 |
110 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.93592612 |
111 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.92789950 |
112 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.92302823 |
113 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.91873890 |
114 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.90474990 |
115 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.90327563 |
116 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 0.90258645 |
117 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.90222053 |
118 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.89609655 |
119 | * PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.89121630 |
120 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.89117612 |
121 | GATA1_19941826_ChIP-Seq_K562_Human | 0.88515820 |
122 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.88057913 |
123 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.87715102 |
124 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.87700448 |
125 | STAT3_23295773_ChIP-Seq_U87_Human | 0.87560533 |
126 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.87512144 |
127 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.87345200 |
128 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.87288518 |
129 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.85630540 |
130 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.85161609 |
131 | * TP63_22573176_ChIP-Seq_HFKS_Human | 0.84795368 |
132 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.84544831 |
133 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.83455962 |
134 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.83431269 |
135 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.82601125 |
136 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.82433216 |
137 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.82119157 |
138 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.81664005 |
139 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.81664005 |
140 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.81061491 |
141 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.80346546 |
142 | * ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.79659982 |
143 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.78994921 |
144 | RXR_22108803_ChIP-Seq_LS180_Human | 0.78956534 |
145 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.78601997 |
146 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.77539959 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002837_dystrophic_cardiac_calcinosis | 5.49753697 |
2 | MP0000751_myopathy | 5.28387742 |
3 | MP0003646_muscle_fatigue | 4.81359617 |
4 | MP0000749_muscle_degeneration | 4.65505442 |
5 | MP0004145_abnormal_muscle_electrophysio | 4.19390856 |
6 | MP0004036_abnormal_muscle_relaxation | 3.92567392 |
7 | MP0004084_abnormal_cardiac_muscle | 3.61704823 |
8 | MP0004130_abnormal_muscle_cell | 3.34885415 |
9 | MP0004087_abnormal_muscle_fiber | 3.18205382 |
10 | MP0000750_abnormal_muscle_regeneration | 3.09199795 |
11 | MP0002106_abnormal_muscle_physiology | 3.03549089 |
12 | MP0005620_abnormal_muscle_contractility | 2.97227867 |
13 | MP0004215_abnormal_myocardial_fiber | 2.96297817 |
14 | MP0005330_cardiomyopathy | 2.88006417 |
15 | MP0000747_muscle_weakness | 2.76351969 |
16 | MP0000759_abnormal_skeletal_muscle | 2.69881895 |
17 | MP0005369_muscle_phenotype | 2.53003167 |
18 | MP0002269_muscular_atrophy | 2.50320147 |
19 | MP0005670_abnormal_white_adipose | 2.45976930 |
20 | MP0005666_abnormal_adipose_tissue | 2.38739483 |
21 | MP0008438_abnormal_cutaneous_collagen | 2.34179496 |
22 | MP0002972_abnormal_cardiac_muscle | 2.21337656 |
23 | MP0004185_abnormal_adipocyte_glucose | 2.10971847 |
24 | MP0008775_abnormal_heart_ventricle | 1.93449321 |
25 | MP0010630_abnormal_cardiac_muscle | 1.91997164 |
26 | MP0002254_reproductive_system_inflammat | 1.88941662 |
27 | MP0005375_adipose_tissue_phenotype | 1.87981629 |
28 | MP0005275_abnormal_skin_tensile | 1.85342831 |
29 | MP0000013_abnormal_adipose_tissue | 1.84961441 |
30 | MP0004484_altered_response_of | 1.81006772 |
31 | MP0001544_abnormal_cardiovascular_syste | 1.80450621 |
32 | MP0005385_cardiovascular_system_phenoty | 1.80450621 |
33 | MP0004233_abnormal_muscle_weight | 1.77897281 |
34 | MP0000733_abnormal_muscle_development | 1.74063242 |
35 | MP0004510_myositis | 1.70206196 |
36 | MP0006138_congestive_heart_failure | 1.66003570 |
37 | MP0002108_abnormal_muscle_morphology | 1.60399291 |
38 | MP0002332_abnormal_exercise_endurance | 1.57365481 |
39 | MP0003950_abnormal_plasma_membrane | 1.56962865 |
40 | MP0003137_abnormal_impulse_conducting | 1.54680106 |
41 | MP0003705_abnormal_hypodermis_morpholog | 1.53079140 |
42 | MP0004270_analgesia | 1.52211899 |
43 | MP0003828_pulmonary_edema | 1.46694468 |
44 | MP0001661_extended_life_span | 1.45091335 |
45 | MP0002971_abnormal_brown_adipose | 1.42663914 |
46 | MP0000003_abnormal_adipose_tissue | 1.37658320 |
47 | MP0003221_abnormal_cardiomyocyte_apopto | 1.19235257 |
48 | MP0006036_abnormal_mitochondrial_physio | 1.17603303 |
49 | MP0001849_ear_inflammation | 1.12584842 |
50 | MP0005451_abnormal_body_composition | 1.10694147 |
51 | MP0003566_abnormal_cell_adhesion | 1.06066841 |
52 | MP0004085_abnormal_heartbeat | 1.05621486 |
53 | MP0003045_fibrosis | 1.02446248 |
54 | MP0000343_altered_response_to | 0.98807511 |
55 | MP0008789_abnormal_olfactory_epithelium | 0.94867794 |
56 | MP0004272_abnormal_basement_membrane | 0.94283773 |
57 | MP0002127_abnormal_cardiovascular_syste | 0.93080440 |
58 | MP0002166_altered_tumor_susceptibility | 0.91356202 |
59 | MP0003279_aneurysm | 0.90375577 |
60 | MP0000230_abnormal_systemic_arterial | 0.87935712 |
61 | MP0009384_cardiac_valve_regurgitation | 0.87450955 |
62 | MP0001879_abnormal_lymphatic_vessel | 0.85540137 |
63 | MP0009115_abnormal_fat_cell | 0.84628973 |
64 | MP0000266_abnormal_heart_morphology | 0.83383791 |
65 | MP0005334_abnormal_fat_pad | 0.81093857 |
66 | MP0001958_emphysema | 0.80698333 |
67 | MP0000462_abnormal_digestive_system | 0.75366663 |
68 | MP0010030_abnormal_orbit_morphology | 0.75316563 |
69 | MP0003879_abnormal_hair_cell | 0.72001744 |
70 | MP0000767_abnormal_smooth_muscle | 0.67106620 |
71 | MP0004134_abnormal_chest_morphology | 0.66852431 |
72 | MP0008961_abnormal_basal_metabolism | 0.66338153 |
73 | MP0002896_abnormal_bone_mineralization | 0.65755288 |
74 | MP0002009_preneoplasia | 0.65412971 |
75 | MP0004883_abnormal_blood_vessel | 0.63248146 |
76 | MP0004147_increased_porphyrin_level | 0.62449623 |
77 | MP0002234_abnormal_pharynx_morphology | 0.62060821 |
78 | MP0002138_abnormal_hepatobiliary_system | 0.61808264 |
79 | MP0005266_abnormal_metabolism | 0.61169348 |
80 | MP0005623_abnormal_meninges_morphology | 0.61066235 |
81 | MP0004858_abnormal_nervous_system | 0.60629845 |
82 | MP0010386_abnormal_urinary_bladder | 0.60343306 |
83 | MP0005503_abnormal_tendon_morphology | 0.59886182 |
84 | MP0010368_abnormal_lymphatic_system | 0.59149624 |
85 | MP0002128_abnormal_blood_circulation | 0.58845462 |
86 | MP0000534_abnormal_ureter_morphology | 0.58687632 |
87 | MP0002909_abnormal_adrenal_gland | 0.58611860 |
88 | MP0009250_abnormal_appendicular_skeleto | 0.58484591 |
89 | MP0003959_abnormal_lean_body | 0.56319641 |
90 | MP0002877_abnormal_melanocyte_morpholog | 0.56228287 |
91 | MP0009780_abnormal_chondrocyte_physiolo | 0.55711417 |
92 | MP0003567_abnormal_fetal_cardiomyocyte | 0.55673765 |
93 | MP0003385_abnormal_body_wall | 0.55095557 |
94 | MP0001664_abnormal_digestion | 0.54777639 |
95 | MP0002168_other_aberrant_phenotype | 0.54618513 |
96 | MP0000538_abnormal_urinary_bladder | 0.53994166 |
97 | MP0000049_abnormal_middle_ear | 0.53191217 |
98 | MP0001542_abnormal_bone_strength | 0.52475496 |
99 | MP0005165_increased_susceptibility_to | 0.50954009 |
100 | MP0002078_abnormal_glucose_homeostasis | 0.50587950 |
101 | MP0001529_abnormal_vocalization | 0.50092886 |
102 | MP0000762_abnormal_tongue_morphology | 0.49879959 |
103 | MP0001756_abnormal_urination | 0.49325315 |
104 | MP0003948_abnormal_gas_homeostasis | 0.49251078 |
105 | MP0002006_tumorigenesis | 0.48928735 |
106 | MP0005164_abnormal_response_to | 0.47440035 |
107 | MP0001485_abnormal_pinna_reflex | 0.47417766 |
108 | MP0005535_abnormal_body_temperature | 0.45830037 |
109 | MP0001784_abnormal_fluid_regulation | 0.45671630 |
110 | MP0003091_abnormal_cell_migration | 0.45609383 |
111 | MP0002114_abnormal_axial_skeleton | 0.45416595 |
112 | MP0002970_abnormal_white_adipose | 0.45322910 |
113 | MP0004043_abnormal_pH_regulation | 0.45300445 |
114 | MP0003941_abnormal_skin_development | 0.44949319 |
115 | MP0003011_delayed_dark_adaptation | 0.43619835 |
116 | MP0002876_abnormal_thyroid_physiology | 0.43034512 |
117 | MP0002933_joint_inflammation | 0.42964763 |
118 | MP0001299_abnormal_eye_distance/ | 0.42450643 |
119 | MP0000249_abnormal_blood_vessel | 0.42159303 |
120 | MP0002133_abnormal_respiratory_system | 0.41890213 |
121 | MP0005388_respiratory_system_phenotype | 0.41890213 |
122 | MP0000516_abnormal_urinary_system | 0.41807701 |
123 | MP0005367_renal/urinary_system_phenotyp | 0.41807701 |
124 | MP0006035_abnormal_mitochondrial_morpho | 0.41447890 |
125 | MP0005452_abnormal_adipose_tissue | 0.41202057 |
126 | MP0001270_distended_abdomen | 0.41075811 |
127 | MP0001614_abnormal_blood_vessel | 0.40070112 |
128 | MP0002060_abnormal_skin_morphology | 0.39945589 |
129 | MP0005319_abnormal_enzyme/_coenzyme | 0.39876810 |
130 | MP0005023_abnormal_wound_healing | 0.38645402 |
131 | MP0006276_abnormal_autonomic_nervous | 0.38532879 |
132 | MP0002925_abnormal_cardiovascular_devel | 0.38172596 |
133 | MP0001348_abnormal_lacrimal_gland | 0.37241467 |
134 | MP0002118_abnormal_lipid_homeostasis | 0.37036263 |
135 | MP0005595_abnormal_vascular_smooth | 0.36648829 |
136 | MP0003191_abnormal_cellular_cholesterol | 0.36375291 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Muscle fiber inclusion bodies (HP:0100299) | 7.46292319 |
2 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 7.18233684 |
3 | Type 1 muscle fiber predominance (HP:0003803) | 7.00887738 |
4 | Exercise-induced myalgia (HP:0003738) | 6.91833005 |
5 | Nemaline bodies (HP:0003798) | 6.64769739 |
6 | Exercise-induced muscle cramps (HP:0003710) | 6.20685782 |
7 | Muscle hypertrophy of the lower extremities (HP:0008968) | 5.97006499 |
8 | Calf muscle hypertrophy (HP:0008981) | 5.91654602 |
9 | Muscle fiber splitting (HP:0003555) | 5.89359074 |
10 | Hyporeflexia of lower limbs (HP:0002600) | 5.53209060 |
11 | Distal arthrogryposis (HP:0005684) | 5.10174421 |
12 | Sudden death (HP:0001699) | 5.09657206 |
13 | Difficulty running (HP:0009046) | 5.04607125 |
14 | Increased connective tissue (HP:0009025) | 4.95171021 |
15 | Abnormality of the calf musculature (HP:0001430) | 4.72695597 |
16 | Myoglobinuria (HP:0002913) | 4.66214598 |
17 | Myopathic facies (HP:0002058) | 4.64846987 |
18 | Round ear (HP:0100830) | 4.43752460 |
19 | EMG: myopathic abnormalities (HP:0003458) | 4.43417885 |
20 | Ulnar deviation of the wrist (HP:0003049) | 4.04921495 |
21 | Ventricular tachycardia (HP:0004756) | 3.98999395 |
22 | Abnormality of skeletal muscle fiber size (HP:0012084) | 3.89674271 |
23 | Myotonia (HP:0002486) | 3.86207380 |
24 | Abnormality of the left ventricular outflow tract (HP:0011103) | 3.80382739 |
25 | Subaortic stenosis (HP:0001682) | 3.80382739 |
26 | Increased variability in muscle fiber diameter (HP:0003557) | 3.78255846 |
27 | Rhabdomyolysis (HP:0003201) | 3.69087145 |
28 | Facial diplegia (HP:0001349) | 3.67364919 |
29 | Right ventricular cardiomyopathy (HP:0011663) | 3.58334265 |
30 | Lipoatrophy (HP:0100578) | 3.54024676 |
31 | Neck muscle weakness (HP:0000467) | 3.51360113 |
32 | Popliteal pterygium (HP:0009756) | 3.50664079 |
33 | Muscle stiffness (HP:0003552) | 3.50288009 |
34 | Calcaneovalgus deformity (HP:0001848) | 3.40776713 |
35 | Difficulty climbing stairs (HP:0003551) | 3.33397973 |
36 | Asymmetric septal hypertrophy (HP:0001670) | 3.27267378 |
37 | Deformed tarsal bones (HP:0008119) | 3.11410903 |
38 | Atrial fibrillation (HP:0005110) | 3.08110458 |
39 | Mildly elevated creatine phosphokinase (HP:0008180) | 3.07917755 |
40 | Absent phalangeal crease (HP:0006109) | 3.06392824 |
41 | Fetal akinesia sequence (HP:0001989) | 3.02495564 |
42 | Frequent falls (HP:0002359) | 2.95513268 |
43 | Type 2 muscle fiber atrophy (HP:0003554) | 2.94392747 |
44 | Primary atrial arrhythmia (HP:0001692) | 2.86104905 |
45 | Scapular winging (HP:0003691) | 2.84600938 |
46 | Rimmed vacuoles (HP:0003805) | 2.82422506 |
47 | Dilated cardiomyopathy (HP:0001644) | 2.81034362 |
48 | Supraventricular tachycardia (HP:0004755) | 2.71672029 |
49 | Supraventricular arrhythmia (HP:0005115) | 2.69967936 |
50 | Spinal rigidity (HP:0003306) | 2.68946179 |
51 | Aortic aneurysm (HP:0004942) | 2.66114909 |
52 | Areflexia of lower limbs (HP:0002522) | 2.64559410 |
53 | Distal lower limb muscle weakness (HP:0009053) | 2.62845482 |
54 | Bundle branch block (HP:0011710) | 2.59292945 |
55 | Muscle fiber atrophy (HP:0100295) | 2.57778964 |
56 | Prolonged QT interval (HP:0001657) | 2.53635825 |
57 | Palpitations (HP:0001962) | 2.53425643 |
58 | Abnormal finger flexion creases (HP:0006143) | 2.46936792 |
59 | Proximal amyotrophy (HP:0007126) | 2.46701170 |
60 | Malignant hyperthermia (HP:0002047) | 2.46297767 |
61 | Gowers sign (HP:0003391) | 2.42056747 |
62 | Slender build (HP:0001533) | 2.39254632 |
63 | Infantile muscular hypotonia (HP:0008947) | 2.37902160 |
64 | Ventricular arrhythmia (HP:0004308) | 2.32865837 |
65 | EMG: neuropathic changes (HP:0003445) | 2.29446318 |
66 | Generalized muscle weakness (HP:0003324) | 2.29045615 |
67 | Bulbar palsy (HP:0001283) | 2.28681024 |
68 | Syncope (HP:0001279) | 2.27458900 |
69 | Abnormality of the calcaneus (HP:0008364) | 2.27446302 |
70 | Fatigable weakness (HP:0003473) | 2.27107413 |
71 | Abnormality of the neuromuscular junction (HP:0003398) | 2.27107413 |
72 | Muscular dystrophy (HP:0003560) | 2.25776049 |
73 | Hypoplastic ischia (HP:0003175) | 2.25321190 |
74 | Nonprogressive disorder (HP:0003680) | 2.24165947 |
75 | Aortic dissection (HP:0002647) | 2.24061319 |
76 | Limb-girdle muscle atrophy (HP:0003797) | 2.22758760 |
77 | Hip contracture (HP:0003273) | 2.22064779 |
78 | Heart block (HP:0012722) | 2.21784241 |
79 | Distal lower limb amyotrophy (HP:0008944) | 2.20746392 |
80 | Broad metatarsal (HP:0001783) | 2.19842025 |
81 | Aplasia of the musculature (HP:0100854) | 2.18951427 |
82 | Increased density of long bones (HP:0006392) | 2.15682974 |
83 | Testicular atrophy (HP:0000029) | 2.15571692 |
84 | Amniotic constriction ring (HP:0009775) | 2.15214986 |
85 | Abnormality of placental membranes (HP:0011409) | 2.15214986 |
86 | Abnormal atrioventricular conduction (HP:0005150) | 2.13467287 |
87 | Waddling gait (HP:0002515) | 2.11523264 |
88 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.10958629 |
89 | Abnormality of the shoulder girdle musculature (HP:0001435) | 2.06619286 |
90 | Limited hip movement (HP:0008800) | 2.06041554 |
91 | Protrusio acetabuli (HP:0003179) | 2.05042344 |
92 | Left ventricular hypertrophy (HP:0001712) | 2.04552055 |
93 | Limb-girdle muscle weakness (HP:0003325) | 2.03673174 |
94 | Atrioventricular block (HP:0001678) | 2.03450143 |
95 | Hyperkalemia (HP:0002153) | 1.98239285 |
96 | Respiratory insufficiency due to muscle weakness (HP:0002747) | 1.97094523 |
97 | Abnormality of the ischium (HP:0003174) | 1.96573924 |
98 | Oligomenorrhea (HP:0000876) | 1.96004452 |
99 | Cerebral aneurysm (HP:0004944) | 1.90075799 |
100 | Weak cry (HP:0001612) | 1.82438031 |
101 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.82092219 |
102 | Tarsal synostosis (HP:0008368) | 1.81588999 |
103 | Ankle contracture (HP:0006466) | 1.80804708 |
104 | Easy fatigability (HP:0003388) | 1.79507028 |
105 | Abnormal EKG (HP:0003115) | 1.75379800 |
106 | Aortic regurgitation (HP:0001659) | 1.71609099 |
107 | Vascular tortuosity (HP:0004948) | 1.69854778 |
108 | Lower limb amyotrophy (HP:0007210) | 1.68699479 |
109 | Foot dorsiflexor weakness (HP:0009027) | 1.68429051 |
110 | Long clavicles (HP:0000890) | 1.68408762 |
111 | Abnormality of the foot musculature (HP:0001436) | 1.67256948 |
112 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.66954990 |
113 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.66954990 |
114 | Progressive muscle weakness (HP:0003323) | 1.66726417 |
115 | Pelvic girdle muscle weakness (HP:0003749) | 1.66348469 |
116 | Neoplasm of the heart (HP:0100544) | 1.64678211 |
117 | Ventricular fibrillation (HP:0001663) | 1.64325516 |
118 | Aneurysm (HP:0002617) | 1.61675962 |
119 | Shoulder girdle muscle weakness (HP:0003547) | 1.61252550 |
120 | Ulnar deviation of finger (HP:0009465) | 1.60062602 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TTN | 6.80241200 |
2 | OBSCN | 6.54513420 |
3 | PHKG1 | 3.79284208 |
4 | PHKG2 | 3.79284208 |
5 | MYLK | 3.76162454 |
6 | DMPK | 3.12733104 |
7 | TRIB3 | 2.93173068 |
8 | PIK3CG | 2.80812140 |
9 | LMTK2 | 2.29688018 |
10 | PDK3 | 2.08754814 |
11 | PDK4 | 2.08754814 |
12 | PIK3CA | 2.06421719 |
13 | BCKDK | 1.68612962 |
14 | NME1 | 1.67637387 |
15 | CCNB1 | 1.66194443 |
16 | MAP3K7 | 1.57600266 |
17 | MAP2K3 | 1.57046087 |
18 | AKT3 | 1.56272753 |
19 | RIPK1 | 1.51493670 |
20 | PDK2 | 1.47628310 |
21 | PRKAA2 | 1.45209376 |
22 | PINK1 | 1.42238933 |
23 | MUSK | 1.36698489 |
24 | PKN2 | 1.36563055 |
25 | LIMK1 | 1.36098846 |
26 | NEK1 | 1.28360755 |
27 | VRK2 | 1.15273356 |
28 | MAPK12 | 1.14508369 |
29 | MARK1 | 1.09187846 |
30 | SIK1 | 1.07744722 |
31 | PDGFRA | 1.04012494 |
32 | MAPKAPK3 | 1.03996444 |
33 | INSRR | 1.02105731 |
34 | CAMK1D | 1.00463012 |
35 | TIE1 | 0.94593833 |
36 | STK24 | 0.92606691 |
37 | PRKAA1 | 0.91841182 |
38 | ILK | 0.91384686 |
39 | TRPM7 | 0.90688279 |
40 | LATS1 | 0.89874331 |
41 | NEK9 | 0.88250604 |
42 | EPHB1 | 0.87077624 |
43 | ROCK1 | 0.85303505 |
44 | CAMK1G | 0.81064605 |
45 | MAP3K3 | 0.80376470 |
46 | MAPK7 | 0.78552376 |
47 | IRAK3 | 0.76240912 |
48 | ZAK | 0.75787702 |
49 | CDC42BPA | 0.74679060 |
50 | PAK2 | 0.73103759 |
51 | PTK6 | 0.72897246 |
52 | PKN1 | 0.70479500 |
53 | JAK1 | 0.68881133 |
54 | TGFBR2 | 0.66502702 |
55 | FLT3 | 0.65726766 |
56 | MAPK4 | 0.64862947 |
57 | NLK | 0.64364167 |
58 | PAK3 | 0.63769263 |
59 | MARK2 | 0.62971085 |
60 | PRKD1 | 0.62746839 |
61 | SGK2 | 0.62459081 |
62 | EPHB2 | 0.62209099 |
63 | MOS | 0.57561726 |
64 | FGFR3 | 0.57417138 |
65 | MELK | 0.55359739 |
66 | TYK2 | 0.54719163 |
67 | PTK2B | 0.53845133 |
68 | CAMK2G | 0.53673401 |
69 | DDR2 | 0.53613707 |
70 | MAP2K4 | 0.53265317 |
71 | STK38L | 0.51032330 |
72 | CAMK2B | 0.50957220 |
73 | CAMK4 | 0.50900521 |
74 | FER | 0.50167638 |
75 | PTK2 | 0.49647464 |
76 | CAMK2D | 0.48251864 |
77 | AKT2 | 0.44818225 |
78 | ERN1 | 0.42650683 |
79 | JAK3 | 0.41294605 |
80 | CDK8 | 0.39638077 |
81 | GRK7 | 0.39570677 |
82 | ROCK2 | 0.39491853 |
83 | CAMK2A | 0.38947743 |
84 | ICK | 0.38822014 |
85 | RET | 0.38374104 |
86 | FGFR4 | 0.37856527 |
87 | MAP2K1 | 0.37564916 |
88 | EPHA3 | 0.37326757 |
89 | MTOR | 0.36554366 |
90 | SGK1 | 0.35910024 |
91 | PRKD2 | 0.35337422 |
92 | SGK223 | 0.34561535 |
93 | SGK494 | 0.34561535 |
94 | MAP3K14 | 0.33941864 |
95 | MST1R | 0.33915428 |
96 | RPS6KA3 | 0.33855117 |
97 | RPS6KA2 | 0.33626341 |
98 | PDPK1 | 0.33611009 |
99 | MAP2K6 | 0.32923465 |
100 | EEF2K | 0.32777682 |
101 | WNK1 | 0.31108377 |
102 | RPS6KB1 | 0.30729801 |
103 | PRKACB | 0.30567281 |
104 | MAP3K10 | 0.30370644 |
105 | STK39 | 0.29763194 |
106 | SGK3 | 0.29761164 |
107 | DAPK3 | 0.29401867 |
108 | MAPK11 | 0.29287606 |
109 | STK38 | 0.29268608 |
110 | JAK2 | 0.28684024 |
111 | FRK | 0.28639546 |
112 | MAP3K5 | 0.28636064 |
113 | PRKACA | 0.28434996 |
114 | MAP3K6 | 0.27133169 |
115 | LATS2 | 0.26160597 |
116 | PRKACG | 0.25138720 |
117 | GSK3A | 0.24199367 |
118 | MAP3K13 | 0.24010174 |
119 | PDGFRB | 0.23995352 |
120 | STK3 | 0.23846554 |
121 | PRKD3 | 0.23643551 |
122 | RPS6KC1 | 0.22767654 |
123 | RPS6KL1 | 0.22767654 |
124 | MAPKAPK2 | 0.22309462 |
125 | PRKCH | 0.21629904 |
126 | RPS6KA1 | 0.21538251 |
127 | TBK1 | 0.21229613 |
128 | PRKG1 | 0.20993088 |
129 | CAMK1 | 0.20434207 |
130 | RPS6KA6 | 0.18161553 |
131 | CDK9 | 0.17708794 |
132 | STK11 | 0.15494681 |
133 | PRKCE | 0.14456606 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 4.37421042 |
2 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 3.88561701 |
3 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 3.73375811 |
4 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.20536860 |
5 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 3.12296683 |
6 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 3.09145189 |
7 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.63939522 |
8 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.19567234 |
9 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.94158226 |
10 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.93592699 |
11 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.86258205 |
12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.78570463 |
13 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.77477757 |
14 | Insulin resistance_Homo sapiens_hsa04931 | 1.77141059 |
15 | Viral myocarditis_Homo sapiens_hsa05416 | 1.70627463 |
16 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.69776866 |
17 | Carbon metabolism_Homo sapiens_hsa01200 | 1.67610770 |
18 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.65181302 |
19 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.64769967 |
20 | Focal adhesion_Homo sapiens_hsa04510 | 1.55965013 |
21 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.55488799 |
22 | AMPK signaling pathway_Homo sapiens_hsa04152 | 1.50492653 |
23 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.47635648 |
24 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.39386085 |
25 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.39280798 |
26 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.38098521 |
27 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.35011851 |
28 | Long-term potentiation_Homo sapiens_hsa04720 | 1.30349898 |
29 | Parkinsons disease_Homo sapiens_hsa05012 | 1.30342546 |
30 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.30287339 |
31 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.30144096 |
32 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.23965915 |
33 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.17034219 |
34 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.13688201 |
35 | Tight junction_Homo sapiens_hsa04530 | 1.12519679 |
36 | Alzheimers disease_Homo sapiens_hsa05010 | 1.09649981 |
37 | Renin secretion_Homo sapiens_hsa04924 | 1.09031580 |
38 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.07301247 |
39 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.01470955 |
40 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.99936910 |
41 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.98652507 |
42 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.92666437 |
43 | Circadian rhythm_Homo sapiens_hsa04710 | 0.91945710 |
44 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.91443527 |
45 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.90026133 |
46 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.88665321 |
47 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.85967725 |
48 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.85829625 |
49 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.84590555 |
50 | Amoebiasis_Homo sapiens_hsa05146 | 0.81878930 |
51 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.78694467 |
52 | Adherens junction_Homo sapiens_hsa04520 | 0.75514722 |
53 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.71221256 |
54 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.68802767 |
55 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.68627084 |
56 | Histidine metabolism_Homo sapiens_hsa00340 | 0.68290928 |
57 | Gap junction_Homo sapiens_hsa04540 | 0.66362355 |
58 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.66294457 |
59 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.65339620 |
60 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.65139084 |
61 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.64478010 |
62 | Platelet activation_Homo sapiens_hsa04611 | 0.63754023 |
63 | GABAergic synapse_Homo sapiens_hsa04727 | 0.60616004 |
64 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.60158727 |
65 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.59950896 |
66 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.59831804 |
67 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.59554873 |
68 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.58511906 |
69 | Galactose metabolism_Homo sapiens_hsa00052 | 0.57861504 |
70 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.57567710 |
71 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.56389589 |
72 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.55244927 |
73 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.53436100 |
74 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.53128791 |
75 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.52858449 |
76 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.52594556 |
77 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.52580358 |
78 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.50592547 |
79 | Long-term depression_Homo sapiens_hsa04730 | 0.50342661 |
80 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.50337316 |
81 | Huntingtons disease_Homo sapiens_hsa05016 | 0.49529364 |
82 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.48157018 |
83 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.47064368 |
84 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.43711060 |
85 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.43597241 |
86 | Glioma_Homo sapiens_hsa05214 | 0.43024373 |
87 | Lysine degradation_Homo sapiens_hsa00310 | 0.41793111 |
88 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.41621225 |
89 | Melanoma_Homo sapiens_hsa05218 | 0.40691639 |
90 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.39494768 |
91 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.37001903 |
92 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.36886136 |
93 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.36031146 |
94 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.35924599 |
95 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.35303767 |
96 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.33870328 |
97 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.33763872 |
98 | Insulin secretion_Homo sapiens_hsa04911 | 0.32680595 |
99 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.32479037 |
100 | Salivary secretion_Homo sapiens_hsa04970 | 0.30327711 |
101 | Olfactory transduction_Homo sapiens_hsa04740 | 0.29552080 |
102 | Axon guidance_Homo sapiens_hsa04360 | 0.29063194 |
103 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.28927992 |
104 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.27344017 |
105 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.26859337 |
106 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.26492109 |
107 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.26031859 |
108 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.25990440 |
109 | Circadian entrainment_Homo sapiens_hsa04713 | 0.23671476 |
110 | Leishmaniasis_Homo sapiens_hsa05140 | 0.22566928 |
111 | ABC transporters_Homo sapiens_hsa02010 | 0.22435634 |
112 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.21806682 |
113 | Melanogenesis_Homo sapiens_hsa04916 | 0.21629815 |
114 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.21582213 |
115 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.21464765 |
116 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.20148402 |
117 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.19552659 |
118 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.18736880 |
119 | Pathways in cancer_Homo sapiens_hsa05200 | 0.18547140 |
120 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.17685794 |
121 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.17543562 |
122 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.17520184 |
123 | Bile secretion_Homo sapiens_hsa04976 | 0.17404279 |