Rank | Gene Set | Z-score |
---|---|---|
1 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 8.23712594 |
2 | regulation of penile erection (GO:0060405) | 6.85537938 |
3 | vocalization behavior (GO:0071625) | 6.28121446 |
4 | cellular potassium ion homeostasis (GO:0030007) | 6.23796454 |
5 | sodium ion export (GO:0071436) | 5.94907331 |
6 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 5.91904263 |
7 | neuron cell-cell adhesion (GO:0007158) | 5.68379496 |
8 | startle response (GO:0001964) | 5.54966145 |
9 | locomotory exploration behavior (GO:0035641) | 5.23428775 |
10 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.14089782 |
11 | neurotransmitter-gated ion channel clustering (GO:0072578) | 5.13690434 |
12 | L-amino acid import (GO:0043092) | 4.95009430 |
13 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 4.84600041 |
14 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.84551612 |
15 | succinate metabolic process (GO:0006105) | 4.84287695 |
16 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 4.83408753 |
17 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 4.58788868 |
18 | presynaptic membrane assembly (GO:0097105) | 4.55056094 |
19 | neurotransmitter secretion (GO:0007269) | 4.54776911 |
20 | synaptic vesicle exocytosis (GO:0016079) | 4.53516777 |
21 | amino acid import (GO:0043090) | 4.39996048 |
22 | neuron-neuron synaptic transmission (GO:0007270) | 4.38731273 |
23 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.37373333 |
24 | potassium ion homeostasis (GO:0055075) | 4.31589105 |
25 | negative regulation of dendrite morphogenesis (GO:0050774) | 4.30021125 |
26 | negative regulation of catecholamine secretion (GO:0033604) | 4.29605253 |
27 | gamma-aminobutyric acid transport (GO:0015812) | 4.25358299 |
28 | exploration behavior (GO:0035640) | 4.22057055 |
29 | positive regulation of synapse maturation (GO:0090129) | 4.19412797 |
30 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.16965624 |
31 | neuronal action potential propagation (GO:0019227) | 4.14788874 |
32 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 4.13210711 |
33 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 4.12034236 |
34 | potassium ion import (GO:0010107) | 4.11731901 |
35 | transferrin transport (GO:0033572) | 4.09874441 |
36 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.08318326 |
37 | regulation of neurotransmitter secretion (GO:0046928) | 4.07125014 |
38 | ATP hydrolysis coupled proton transport (GO:0015991) | 4.07069999 |
39 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 4.07069999 |
40 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.06667289 |
41 | positive regulation of membrane potential (GO:0045838) | 4.04729151 |
42 | long-term synaptic potentiation (GO:0060291) | 4.04416399 |
43 | neuronal ion channel clustering (GO:0045161) | 4.03570611 |
44 | regulation of voltage-gated calcium channel activity (GO:1901385) | 4.00273911 |
45 | central nervous system myelination (GO:0022010) | 3.99721795 |
46 | axon ensheathment in central nervous system (GO:0032291) | 3.99721795 |
47 | presynaptic membrane organization (GO:0097090) | 3.99250996 |
48 | glutamate receptor signaling pathway (GO:0007215) | 3.92110696 |
49 | protein localization to synapse (GO:0035418) | 3.91894905 |
50 | cell communication by electrical coupling (GO:0010644) | 3.90899243 |
51 | synaptic transmission, glutamatergic (GO:0035249) | 3.90167049 |
52 | postsynaptic membrane organization (GO:0001941) | 3.87815354 |
53 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.87102180 |
54 | cellular sodium ion homeostasis (GO:0006883) | 3.86081660 |
55 | trivalent inorganic cation transport (GO:0072512) | 3.85160723 |
56 | ferric iron transport (GO:0015682) | 3.85160723 |
57 | synaptic vesicle endocytosis (GO:0048488) | 3.83872528 |
58 | regulation of synapse maturation (GO:0090128) | 3.83090234 |
59 | neurotransmitter uptake (GO:0001504) | 3.82953728 |
60 | neuromuscular process controlling balance (GO:0050885) | 3.82595785 |
61 | behavioral defense response (GO:0002209) | 3.82352529 |
62 | behavioral fear response (GO:0001662) | 3.82352529 |
63 | regulation of female receptivity (GO:0045924) | 3.80250836 |
64 | layer formation in cerebral cortex (GO:0021819) | 3.79479796 |
65 | positive regulation of dendritic spine development (GO:0060999) | 3.79451391 |
66 | female mating behavior (GO:0060180) | 3.79392703 |
67 | dendritic spine morphogenesis (GO:0060997) | 3.77853355 |
68 | negative regulation of amine transport (GO:0051953) | 3.70033746 |
69 | membrane depolarization during action potential (GO:0086010) | 3.69919147 |
70 | regulation of neurotransmitter transport (GO:0051588) | 3.69604706 |
71 | regulation of vesicle fusion (GO:0031338) | 3.67671467 |
72 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.67515855 |
73 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.65493703 |
74 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.63874008 |
75 | positive regulation of synapse assembly (GO:0051965) | 3.62788949 |
76 | cellular response to ammonium ion (GO:0071242) | 3.61322737 |
77 | neurotransmitter biosynthetic process (GO:0042136) | 3.60175742 |
78 | auditory behavior (GO:0031223) | 3.59688831 |
79 | regulation of synaptic vesicle transport (GO:1902803) | 3.57521008 |
80 | cerebellar granule cell differentiation (GO:0021707) | 3.54249869 |
81 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.54062497 |
82 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.53157755 |
83 | positive regulation of neurotransmitter transport (GO:0051590) | 3.52901454 |
84 | membrane depolarization (GO:0051899) | 3.50282664 |
85 | response to histamine (GO:0034776) | 3.49359439 |
86 | regulation of ARF protein signal transduction (GO:0032012) | 3.49069143 |
87 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.48796151 |
88 | neurotransmitter transport (GO:0006836) | 3.48391371 |
89 | glutamate secretion (GO:0014047) | 3.48078747 |
90 | regulation of synaptic transmission, GABAergic (GO:0032228) | 3.47677702 |
91 | prostate gland growth (GO:0060736) | 3.44882939 |
92 | synaptic vesicle maturation (GO:0016188) | 3.44693322 |
93 | synaptic transmission, dopaminergic (GO:0001963) | 3.44679644 |
94 | regulation of action potential (GO:0098900) | 3.41592642 |
95 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 3.39726642 |
96 | negative regulation of norepinephrine secretion (GO:0010700) | 3.38982628 |
97 | long-term memory (GO:0007616) | 3.38824850 |
98 | acidic amino acid transport (GO:0015800) | 3.38687706 |
99 | regulation of dendritic spine development (GO:0060998) | 3.37207726 |
100 | response to cocaine (GO:0042220) | 3.37198424 |
101 | fear response (GO:0042596) | 3.36667240 |
102 | negative regulation of dendrite development (GO:2000171) | 3.36511286 |
103 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.36148850 |
104 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.34100801 |
105 | cell communication involved in cardiac conduction (GO:0086065) | 3.33836845 |
106 | aggressive behavior (GO:0002118) | 3.33174498 |
107 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.28122850 |
108 | regulation of synaptic transmission (GO:0050804) | 3.27947687 |
109 | neuromuscular process controlling posture (GO:0050884) | 3.27782166 |
110 | detection of calcium ion (GO:0005513) | 3.27742336 |
111 | transmission of nerve impulse (GO:0019226) | 3.26709719 |
112 | regulation of neurotransmitter levels (GO:0001505) | 3.24495486 |
113 | regulation of glutamate secretion (GO:0014048) | 3.24031141 |
114 | synaptic vesicle transport (GO:0048489) | 3.20281595 |
115 | establishment of synaptic vesicle localization (GO:0097480) | 3.20281595 |
116 | striatum development (GO:0021756) | 3.19295594 |
117 | regulation of dopamine secretion (GO:0014059) | 3.18694067 |
118 | phenylpropanoid metabolic process (GO:0009698) | 3.16082368 |
119 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.15972370 |
120 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 3.12556243 |
121 | neuromuscular process (GO:0050905) | 3.12151069 |
122 | synapse assembly (GO:0007416) | 3.11349145 |
123 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.09051423 |
124 | dendritic spine organization (GO:0097061) | 3.07655563 |
125 | response to auditory stimulus (GO:0010996) | 3.07340497 |
126 | dicarboxylic acid catabolic process (GO:0043649) | 3.05517324 |
127 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.05306476 |
128 | vesicle docking involved in exocytosis (GO:0006904) | 3.04025906 |
129 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.03253779 |
130 | synaptic transmission (GO:0007268) | 3.03019907 |
131 | protein-cofactor linkage (GO:0018065) | 3.02396092 |
132 | L-glutamate transport (GO:0015813) | 3.00797234 |
133 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.00392043 |
134 | positive regulation of synaptic transmission (GO:0050806) | 3.00179407 |
135 | multicellular organismal reproductive behavior (GO:0033057) | 2.99906652 |
136 | positive regulation of action potential (GO:0045760) | 2.98283939 |
137 | regulation of sensory perception (GO:0051931) | 2.97552318 |
138 | regulation of sensory perception of pain (GO:0051930) | 2.97552318 |
139 | neuromuscular synaptic transmission (GO:0007274) | 2.97374813 |
140 | learning (GO:0007612) | 2.96560225 |
141 | phagosome maturation (GO:0090382) | 2.94260381 |
142 | regulation of synaptic plasticity (GO:0048167) | 2.94237622 |
143 | neuron recognition (GO:0008038) | 2.93631334 |
144 | proline transport (GO:0015824) | 2.93188559 |
145 | serotonin receptor signaling pathway (GO:0007210) | 2.93080622 |
146 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 2.92513590 |
147 | regulation of postsynaptic membrane potential (GO:0060078) | 2.91609142 |
148 | regulation of synapse structural plasticity (GO:0051823) | 2.90984185 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.43286816 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 4.43715665 |
3 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.35959826 |
4 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.07786840 |
5 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.07708972 |
6 | * TAF15_26573619_Chip-Seq_HEK293_Human | 2.95892099 |
7 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.93219949 |
8 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.91620884 |
9 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.64080420 |
10 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.48729317 |
11 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.46837016 |
12 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.46395302 |
13 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.46292605 |
14 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.45035623 |
15 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.43801287 |
16 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.42844956 |
17 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.42485575 |
18 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.42485575 |
19 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.37403208 |
20 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.37339744 |
21 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.24898238 |
22 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.24062581 |
23 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.23495080 |
24 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.10353295 |
25 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.07609053 |
26 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.07215377 |
27 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 2.04854251 |
28 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.98661220 |
29 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.94682193 |
30 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.93372993 |
31 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.91429196 |
32 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.89067362 |
33 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.87494291 |
34 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.84101596 |
35 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.83142724 |
36 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.77554263 |
37 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.76281933 |
38 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.73077625 |
39 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.72295998 |
40 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.71480445 |
41 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.68954791 |
42 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.66333373 |
43 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.65979152 |
44 | FUS_26573619_Chip-Seq_HEK293_Human | 1.65798687 |
45 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.62294694 |
46 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.61745973 |
47 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.59585955 |
48 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.54039992 |
49 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.52374302 |
50 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.52036023 |
51 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.51974864 |
52 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.51799097 |
53 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.50951522 |
54 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.47720277 |
55 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.47069832 |
56 | AR_25329375_ChIP-Seq_VCAP_Human | 1.45270593 |
57 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.43669099 |
58 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.43425173 |
59 | VDR_22108803_ChIP-Seq_LS180_Human | 1.41964260 |
60 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.41675861 |
61 | * ER_23166858_ChIP-Seq_MCF-7_Human | 1.41225390 |
62 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.40841950 |
63 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.36550143 |
64 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.31268025 |
65 | KDM2B_26808549_Chip-Seq_K562_Human | 1.29473907 |
66 | * CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.29229851 |
67 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.28335143 |
68 | STAT3_23295773_ChIP-Seq_U87_Human | 1.27894910 |
69 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.25752030 |
70 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.25015340 |
71 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.23948267 |
72 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.22971738 |
73 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.22427649 |
74 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.22144986 |
75 | JUN_21703547_ChIP-Seq_K562_Human | 1.20458311 |
76 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.20137185 |
77 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.19688712 |
78 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.19261791 |
79 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.18763591 |
80 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.17766950 |
81 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.17488670 |
82 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.14439981 |
83 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.13760455 |
84 | * CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.13656963 |
85 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.13221012 |
86 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.12818821 |
87 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.12567892 |
88 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.11371286 |
89 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.10839828 |
90 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.10171371 |
91 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.09751827 |
92 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.09574583 |
93 | AR_19668381_ChIP-Seq_PC3_Human | 1.07556328 |
94 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.07009718 |
95 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.06834365 |
96 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.06286239 |
97 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.05893904 |
98 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.04934244 |
99 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.03909103 |
100 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.02952507 |
101 | KDM2B_26808549_Chip-Seq_REH_Human | 1.02383775 |
102 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.99965617 |
103 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.98690555 |
104 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.98654484 |
105 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.98045518 |
106 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.97823829 |
107 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95269272 |
108 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.95150371 |
109 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.94105235 |
110 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.93961007 |
111 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.92447795 |
112 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.92345374 |
113 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.91569316 |
114 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.91569316 |
115 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.91108118 |
116 | * FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.90074273 |
117 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.89173587 |
118 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.88959806 |
119 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.88139857 |
120 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.88068663 |
121 | * MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.87848314 |
122 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.87051658 |
123 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.86318888 |
124 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.85256689 |
125 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.85041475 |
126 | DPY_21335234_ChIP-Seq_ESCs_Mouse | 0.84181525 |
127 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.81153751 |
128 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.78573244 |
129 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.78098555 |
130 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.77565263 |
131 | * POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.77517020 |
132 | * TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.77517020 |
133 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.77113087 |
134 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.76152713 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002822_catalepsy | 5.33840711 |
2 | MP0004859_abnormal_synaptic_plasticity | 4.48946385 |
3 | MP0009745_abnormal_behavioral_response | 3.54906080 |
4 | MP0003635_abnormal_synaptic_transmissio | 3.52579256 |
5 | MP0009046_muscle_twitch | 3.39137668 |
6 | MP0003880_abnormal_central_pattern | 3.37533385 |
7 | MP0002064_seizures | 3.29694381 |
8 | MP0002735_abnormal_chemical_nociception | 3.22536655 |
9 | MP0001968_abnormal_touch/_nociception | 3.14230781 |
10 | MP0002063_abnormal_learning/memory/cond | 2.96564155 |
11 | MP0009780_abnormal_chondrocyte_physiolo | 2.85418831 |
12 | MP0002736_abnormal_nociception_after | 2.83697195 |
13 | MP0002272_abnormal_nervous_system | 2.79976761 |
14 | MP0002572_abnormal_emotion/affect_behav | 2.69941194 |
15 | MP0002734_abnormal_mechanical_nocicepti | 2.61336697 |
16 | MP0003787_abnormal_imprinting | 2.61198840 |
17 | MP0005646_abnormal_pituitary_gland | 2.57545748 |
18 | MP0004270_analgesia | 2.42337855 |
19 | MP0001501_abnormal_sleep_pattern | 2.33031859 |
20 | MP0001188_hyperpigmentation | 2.23088890 |
21 | MP0002876_abnormal_thyroid_physiology | 2.19594338 |
22 | MP0003122_maternal_imprinting | 2.15686825 |
23 | MP0002837_dystrophic_cardiac_calcinosis | 2.13069732 |
24 | MP0001486_abnormal_startle_reflex | 2.08005304 |
25 | MP0001970_abnormal_pain_threshold | 2.03978570 |
26 | MP0003183_abnormal_peptide_metabolism | 2.00468090 |
27 | MP0002067_abnormal_sensory_capabilities | 1.97609272 |
28 | MP0005423_abnormal_somatic_nervous | 1.96933181 |
29 | MP0002733_abnormal_thermal_nociception | 1.95254592 |
30 | MP0001986_abnormal_taste_sensitivity | 1.86230831 |
31 | MP0003690_abnormal_glial_cell | 1.77098227 |
32 | MP0006276_abnormal_autonomic_nervous | 1.74127303 |
33 | MP0002184_abnormal_innervation | 1.72979069 |
34 | MP0004142_abnormal_muscle_tone | 1.70250972 |
35 | MP0008260_abnormal_autophagy | 1.65901117 |
36 | MP0000920_abnormal_myelination | 1.63964185 |
37 | MP0003879_abnormal_hair_cell | 1.63013339 |
38 | MP0002557_abnormal_social/conspecific_i | 1.60823333 |
39 | MP0001529_abnormal_vocalization | 1.59278421 |
40 | MP0000013_abnormal_adipose_tissue | 1.50456621 |
41 | MP0003329_amyloid_beta_deposits | 1.48030141 |
42 | MP0001440_abnormal_grooming_behavior | 1.48024640 |
43 | MP0005386_behavior/neurological_phenoty | 1.46188709 |
44 | MP0004924_abnormal_behavior | 1.46188709 |
45 | MP0008877_abnormal_DNA_methylation | 1.33374302 |
46 | MP0008569_lethality_at_weaning | 1.30732405 |
47 | MP0004811_abnormal_neuron_physiology | 1.29799412 |
48 | MP0002909_abnormal_adrenal_gland | 1.28937162 |
49 | MP0002066_abnormal_motor_capabilities/c | 1.27952393 |
50 | MP0001984_abnormal_olfaction | 1.25681918 |
51 | MP0002882_abnormal_neuron_morphology | 1.20622242 |
52 | MP0005171_absent_coat_pigmentation | 1.14345950 |
53 | MP0000955_abnormal_spinal_cord | 1.12955605 |
54 | MP0001270_distended_abdomen | 1.11875571 |
55 | MP0001905_abnormal_dopamine_level | 1.11092188 |
56 | MP0004885_abnormal_endolymph | 1.10618959 |
57 | MP0000778_abnormal_nervous_system | 1.08813722 |
58 | MP0010386_abnormal_urinary_bladder | 1.07601799 |
59 | MP0005551_abnormal_eye_electrophysiolog | 1.07159744 |
60 | MP0004085_abnormal_heartbeat | 0.99146188 |
61 | MP0005645_abnormal_hypothalamus_physiol | 0.98926694 |
62 | MP0003638_abnormal_response/metabolism_ | 0.98300451 |
63 | MP0002069_abnormal_eating/drinking_beha | 0.96159370 |
64 | MP0003121_genomic_imprinting | 0.95520477 |
65 | MP0004858_abnormal_nervous_system | 0.89514446 |
66 | MP0001963_abnormal_hearing_physiology | 0.89115068 |
67 | MP0003633_abnormal_nervous_system | 0.88606816 |
68 | MP0003631_nervous_system_phenotype | 0.88051963 |
69 | MP0001485_abnormal_pinna_reflex | 0.87712907 |
70 | MP0002229_neurodegeneration | 0.87706334 |
71 | MP0001177_atelectasis | 0.86283429 |
72 | MP0004147_increased_porphyrin_level | 0.85022904 |
73 | MP0003123_paternal_imprinting | 0.84639385 |
74 | MP0001346_abnormal_lacrimal_gland | 0.84521280 |
75 | MP0000751_myopathy | 0.83611260 |
76 | MP0004043_abnormal_pH_regulation | 0.82148600 |
77 | MP0003632_abnormal_nervous_system | 0.81945501 |
78 | MP0001664_abnormal_digestion | 0.81294909 |
79 | MP0008874_decreased_physiological_sensi | 0.80948205 |
80 | MP0003938_abnormal_ear_development | 0.79954532 |
81 | MP0001348_abnormal_lacrimal_gland | 0.79150400 |
82 | MP0002152_abnormal_brain_morphology | 0.78558492 |
83 | MP0005167_abnormal_blood-brain_barrier | 0.78260167 |
84 | MP0002752_abnormal_somatic_nervous | 0.75417600 |
85 | MP0004215_abnormal_myocardial_fiber | 0.75269693 |
86 | MP0002163_abnormal_gland_morphology | 0.74619448 |
87 | MP0005379_endocrine/exocrine_gland_phen | 0.74471106 |
88 | MP0003075_altered_response_to | 0.73566514 |
89 | MP0008872_abnormal_physiological_respon | 0.72879339 |
90 | MP0002638_abnormal_pupillary_reflex | 0.72321184 |
91 | MP0002108_abnormal_muscle_morphology | 0.71964029 |
92 | MP0004233_abnormal_muscle_weight | 0.71859716 |
93 | MP0000681_abnormal_thyroid_gland | 0.70555009 |
94 | MP0002332_abnormal_exercise_endurance | 0.69638006 |
95 | MP0000604_amyloidosis | 0.69047085 |
96 | MP0004742_abnormal_vestibular_system | 0.66852013 |
97 | MP0003137_abnormal_impulse_conducting | 0.64716602 |
98 | MP0004782_abnormal_surfactant_physiolog | 0.64324398 |
99 | MP0003634_abnormal_glial_cell | 0.64262316 |
100 | MP0000631_abnormal_neuroendocrine_gland | 0.63638665 |
101 | MP0003646_muscle_fatigue | 0.63350889 |
102 | MP0001502_abnormal_circadian_rhythm | 0.61552869 |
103 | MP0001542_abnormal_bone_strength | 0.61326467 |
104 | MP0000026_abnormal_inner_ear | 0.59808974 |
105 | MP0005448_abnormal_energy_balance | 0.58648480 |
106 | MP0005535_abnormal_body_temperature | 0.58553520 |
107 | MP0003718_maternal_effect | 0.58466790 |
108 | MP0005623_abnormal_meninges_morphology | 0.58220390 |
109 | MP0010769_abnormal_survival | 0.56929948 |
110 | MP0001943_abnormal_respiration | 0.55589518 |
111 | MP0002090_abnormal_vision | 0.54996095 |
112 | MP0005187_abnormal_penis_morphology | 0.54923701 |
113 | MP0000569_abnormal_digit_pigmentation | 0.54868968 |
114 | MP0010770_preweaning_lethality | 0.53694650 |
115 | MP0002082_postnatal_lethality | 0.53694650 |
116 | MP0010768_mortality/aging | 0.53646856 |
117 | MP0003956_abnormal_body_size | 0.49869402 |
118 | MP0003861_abnormal_nervous_system | 0.47756929 |
119 | MP0000579_abnormal_nail_morphology | 0.44995018 |
120 | MP0004130_abnormal_muscle_cell | 0.44576265 |
121 | MP0003172_abnormal_lysosome_physiology | 0.42740984 |
122 | MP0002873_normal_phenotype | 0.41702301 |
123 | MP0002169_no_abnormal_phenotype | 0.39907496 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 7.57837966 |
2 | Atonic seizures (HP:0010819) | 6.27275979 |
3 | Hyperventilation (HP:0002883) | 6.16822432 |
4 | Febrile seizures (HP:0002373) | 5.62849251 |
5 | Epileptic encephalopathy (HP:0200134) | 5.27940711 |
6 | Supranuclear gaze palsy (HP:0000605) | 5.04650691 |
7 | Focal seizures (HP:0007359) | 4.94614570 |
8 | Myokymia (HP:0002411) | 4.41352845 |
9 | Ankle clonus (HP:0011448) | 4.37589831 |
10 | Absence seizures (HP:0002121) | 4.24844491 |
11 | Neurofibrillary tangles (HP:0002185) | 4.02061411 |
12 | Dialeptic seizures (HP:0011146) | 4.01690845 |
13 | Spastic gait (HP:0002064) | 4.00366606 |
14 | Abnormal hair whorl (HP:0010721) | 3.94936831 |
15 | Cerebral hypomyelination (HP:0006808) | 3.73742068 |
16 | Mutism (HP:0002300) | 3.72609931 |
17 | Papilledema (HP:0001085) | 3.65947429 |
18 | Poor suck (HP:0002033) | 3.65924182 |
19 | Generalized tonic-clonic seizures (HP:0002069) | 3.52526513 |
20 | Hemiplegia (HP:0002301) | 3.46216281 |
21 | Progressive cerebellar ataxia (HP:0002073) | 3.45714544 |
22 | Progressive inability to walk (HP:0002505) | 3.41358892 |
23 | Pheochromocytoma (HP:0002666) | 3.39488984 |
24 | Failure to thrive in infancy (HP:0001531) | 3.35905952 |
25 | Annular pancreas (HP:0001734) | 3.31129379 |
26 | Polyphagia (HP:0002591) | 3.28187822 |
27 | Oligomenorrhea (HP:0000876) | 3.24618625 |
28 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.24531144 |
29 | Broad-based gait (HP:0002136) | 3.23622083 |
30 | Cerebral inclusion bodies (HP:0100314) | 3.23353079 |
31 | Hyperthyroidism (HP:0000836) | 3.22374474 |
32 | Neuroendocrine neoplasm (HP:0100634) | 3.21855202 |
33 | Intention tremor (HP:0002080) | 3.20161473 |
34 | Tetraplegia (HP:0002445) | 3.18894337 |
35 | Status epilepticus (HP:0002133) | 3.16699931 |
36 | Gaze-evoked nystagmus (HP:0000640) | 3.16697077 |
37 | Hemiparesis (HP:0001269) | 3.15854033 |
38 | Visual hallucinations (HP:0002367) | 3.14749321 |
39 | Obstructive sleep apnea (HP:0002870) | 3.06372829 |
40 | Resting tremor (HP:0002322) | 3.05848870 |
41 | Focal dystonia (HP:0004373) | 3.04124005 |
42 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.96044946 |
43 | Urinary urgency (HP:0000012) | 2.92614156 |
44 | Acute necrotizing encephalopathy (HP:0006965) | 2.91651743 |
45 | Abnormality of the corticospinal tract (HP:0002492) | 2.87715787 |
46 | Delusions (HP:0000746) | 2.83974450 |
47 | Gait imbalance (HP:0002141) | 2.83222265 |
48 | Lower limb muscle weakness (HP:0007340) | 2.81711797 |
49 | Craniofacial dystonia (HP:0012179) | 2.81538292 |
50 | Abnormality of the labia minora (HP:0012880) | 2.80661708 |
51 | Peripheral hypomyelination (HP:0007182) | 2.76442203 |
52 | Abnormal eating behavior (HP:0100738) | 2.75772848 |
53 | Blue irides (HP:0000635) | 2.71818400 |
54 | Medial flaring of the eyebrow (HP:0010747) | 2.71126418 |
55 | Epileptiform EEG discharges (HP:0011182) | 2.65218600 |
56 | Apathy (HP:0000741) | 2.65125891 |
57 | Impaired social interactions (HP:0000735) | 2.65011769 |
58 | Abnormal social behavior (HP:0012433) | 2.65011769 |
59 | Progressive macrocephaly (HP:0004481) | 2.64893486 |
60 | Congenital primary aphakia (HP:0007707) | 2.64467235 |
61 | Excessive salivation (HP:0003781) | 2.62926046 |
62 | Drooling (HP:0002307) | 2.62926046 |
63 | Impaired smooth pursuit (HP:0007772) | 2.62156856 |
64 | Truncal ataxia (HP:0002078) | 2.61415331 |
65 | Protruding tongue (HP:0010808) | 2.58727071 |
66 | Sensory axonal neuropathy (HP:0003390) | 2.55875108 |
67 | Dysdiadochokinesis (HP:0002075) | 2.53960064 |
68 | EEG with generalized epileptiform discharges (HP:0011198) | 2.53525894 |
69 | Split foot (HP:0001839) | 2.52615490 |
70 | Absent speech (HP:0001344) | 2.52471198 |
71 | Clonus (HP:0002169) | 2.50142829 |
72 | Narrow nasal bridge (HP:0000446) | 2.49794376 |
73 | Nephrogenic diabetes insipidus (HP:0009806) | 2.49180466 |
74 | Hypsarrhythmia (HP:0002521) | 2.46726051 |
75 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.46423396 |
76 | Inability to walk (HP:0002540) | 2.41137844 |
77 | Rigidity (HP:0002063) | 2.36549361 |
78 | Esotropia (HP:0000565) | 2.36118954 |
79 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.35963972 |
80 | Diplopia (HP:0000651) | 2.35239314 |
81 | Abnormality of binocular vision (HP:0011514) | 2.35239314 |
82 | Diminished motivation (HP:0000745) | 2.35056016 |
83 | Hypothermia (HP:0002045) | 2.34351377 |
84 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.34187906 |
85 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.34187906 |
86 | Specific learning disability (HP:0001328) | 2.34081766 |
87 | Neoplasm of the peripheral nervous system (HP:0100007) | 2.34020594 |
88 | Spastic tetraparesis (HP:0001285) | 2.31282360 |
89 | CNS hypomyelination (HP:0003429) | 2.30425740 |
90 | Poor eye contact (HP:0000817) | 2.29262335 |
91 | Generalized hypotonia (HP:0001290) | 2.28257132 |
92 | Anxiety (HP:0000739) | 2.27906570 |
93 | Thyroid-stimulating hormone excess (HP:0002925) | 2.24357057 |
94 | Acute encephalopathy (HP:0006846) | 2.23746044 |
95 | Thickened helices (HP:0000391) | 2.22937735 |
96 | Stereotypic behavior (HP:0000733) | 2.22213604 |
97 | Depression (HP:0000716) | 2.20746040 |
98 | Cholecystitis (HP:0001082) | 2.20376048 |
99 | Abnormal gallbladder physiology (HP:0012438) | 2.20376048 |
100 | Rapidly progressive (HP:0003678) | 2.19883052 |
101 | Choreoathetosis (HP:0001266) | 2.18702483 |
102 | Growth hormone deficiency (HP:0000824) | 2.17581575 |
103 | Sleep apnea (HP:0010535) | 2.17033100 |
104 | Amblyopia (HP:0000646) | 2.15378651 |
105 | Incomplete penetrance (HP:0003829) | 2.14833648 |
106 | Genital tract atresia (HP:0001827) | 2.13784936 |
107 | Impaired pain sensation (HP:0007328) | 2.13647829 |
108 | Abnormality of pain sensation (HP:0010832) | 2.13647829 |
109 | Ventricular fibrillation (HP:0001663) | 2.13268292 |
110 | Vaginal atresia (HP:0000148) | 2.11501377 |
111 | Postural instability (HP:0002172) | 2.09584787 |
112 | Insomnia (HP:0100785) | 2.09006914 |
113 | Dysmetric saccades (HP:0000641) | 2.06964512 |
114 | Mitochondrial inheritance (HP:0001427) | 2.06412326 |
115 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.04614741 |
116 | Limb dystonia (HP:0002451) | 2.04379074 |
117 | Increased circulating renin level (HP:0000848) | 2.04164002 |
118 | Abnormality of saccadic eye movements (HP:0000570) | 2.02948920 |
119 | Gait ataxia (HP:0002066) | 2.01284225 |
120 | Action tremor (HP:0002345) | 2.01000855 |
121 | Akinesia (HP:0002304) | 1.99238153 |
122 | Bradykinesia (HP:0002067) | 1.96954542 |
123 | Dysmetria (HP:0001310) | 1.96126371 |
124 | Fetal akinesia sequence (HP:0001989) | 1.94772075 |
125 | Amyotrophic lateral sclerosis (HP:0007354) | 1.91925079 |
126 | Abnormality of the vocal cords (HP:0008777) | 1.91282031 |
127 | Bundle branch block (HP:0011710) | 1.91128880 |
128 | Megalencephaly (HP:0001355) | 1.88314901 |
129 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.88061319 |
130 | Spastic diplegia (HP:0001264) | 1.87665092 |
131 | Memory impairment (HP:0002354) | 1.87123321 |
132 | Lower limb asymmetry (HP:0100559) | 1.85273655 |
133 | Psychosis (HP:0000709) | 1.85168474 |
134 | Neuronal loss in central nervous system (HP:0002529) | 1.84271387 |
135 | Spastic tetraplegia (HP:0002510) | 1.82977881 |
136 | Optic disc pallor (HP:0000543) | 1.82489022 |
137 | Hip dysplasia (HP:0001385) | 1.80688278 |
138 | Abnormality of salivation (HP:0100755) | 1.79730503 |
139 | Postural tremor (HP:0002174) | 1.78949958 |
140 | Torticollis (HP:0000473) | 1.78805181 |
141 | Poor coordination (HP:0002370) | 1.78132084 |
142 | Fair hair (HP:0002286) | 1.77504428 |
143 | Hypoventilation (HP:0002791) | 1.77348941 |
144 | Labial hypoplasia (HP:0000066) | 1.77204724 |
145 | Impaired vibratory sensation (HP:0002495) | 1.75901915 |
146 | Genetic anticipation (HP:0003743) | 1.75500109 |
147 | Abnormality of the lower motor neuron (HP:0002366) | 1.74112006 |
148 | Scanning speech (HP:0002168) | 1.73008661 |
149 | Unsteady gait (HP:0002317) | 1.72772088 |
150 | Increased CSF lactate (HP:0002490) | 1.71689270 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CASK | 6.65390903 |
2 | NTRK3 | 4.51576389 |
3 | AKT3 | 3.57362402 |
4 | TSSK6 | 3.05219445 |
5 | MAP3K12 | 2.94198334 |
6 | MAP2K7 | 2.80477316 |
7 | PRPF4B | 2.62313632 |
8 | EPHA4 | 2.59935674 |
9 | MAP3K4 | 2.32475232 |
10 | PLK2 | 2.12693522 |
11 | ERBB4 | 2.07448968 |
12 | PRKD3 | 1.96616194 |
13 | SIK3 | 1.87181774 |
14 | LATS2 | 1.77736688 |
15 | NTRK2 | 1.75586222 |
16 | GRK5 | 1.72229287 |
17 | MUSK | 1.71332183 |
18 | MINK1 | 1.68881693 |
19 | PRKCG | 1.56576240 |
20 | MAP2K4 | 1.50628800 |
21 | MAP3K9 | 1.48771161 |
22 | SGK2 | 1.48485953 |
23 | PDK3 | 1.45669349 |
24 | PDK4 | 1.45669349 |
25 | DAPK1 | 1.44081326 |
26 | RIPK1 | 1.41168256 |
27 | SGK494 | 1.40276341 |
28 | SGK223 | 1.40276341 |
29 | MARK1 | 1.35367723 |
30 | ADRBK2 | 1.34436205 |
31 | PRKCE | 1.34204445 |
32 | BRAF | 1.22159804 |
33 | TNIK | 1.22020442 |
34 | CDK8 | 1.14970151 |
35 | PAK3 | 1.11316091 |
36 | CCNB1 | 1.09888629 |
37 | CAMK2A | 1.09701206 |
38 | TYRO3 | 1.06995736 |
39 | DAPK2 | 1.06875072 |
40 | MAPK13 | 1.05081700 |
41 | CDK5 | 1.04984403 |
42 | CDK11A | 1.03621579 |
43 | PDK2 | 0.99962218 |
44 | BCR | 0.98879480 |
45 | OXSR1 | 0.98836296 |
46 | MAP3K13 | 0.98171419 |
47 | SGK3 | 0.97698810 |
48 | ALK | 0.93890175 |
49 | CAMK2B | 0.93219341 |
50 | RIPK4 | 0.92658974 |
51 | UHMK1 | 0.90332148 |
52 | FES | 0.89149638 |
53 | YES1 | 0.86640802 |
54 | NTRK1 | 0.85673152 |
55 | PINK1 | 0.82946513 |
56 | CAMK4 | 0.82597732 |
57 | MARK2 | 0.81878837 |
58 | MAPK12 | 0.81740479 |
59 | STK11 | 0.79911086 |
60 | PAK6 | 0.78299946 |
61 | MATK | 0.78186985 |
62 | CDK19 | 0.78110699 |
63 | PKN1 | 0.77318381 |
64 | SIK2 | 0.77050592 |
65 | PRKCH | 0.76399250 |
66 | CAMK2G | 0.75428507 |
67 | MYLK | 0.74765894 |
68 | WNK1 | 0.74197909 |
69 | CAMK2D | 0.73325532 |
70 | ARAF | 0.71976457 |
71 | TNK2 | 0.69710336 |
72 | MAPK10 | 0.67964888 |
73 | WNK3 | 0.65997197 |
74 | PDK1 | 0.63156456 |
75 | PHKG1 | 0.61287268 |
76 | PHKG2 | 0.61287268 |
77 | NME1 | 0.61178017 |
78 | RAF1 | 0.60149336 |
79 | BMPR2 | 0.58966680 |
80 | CAMKK2 | 0.57140176 |
81 | KSR1 | 0.56914305 |
82 | PTK2B | 0.56082335 |
83 | FER | 0.55988048 |
84 | CDK14 | 0.55125735 |
85 | MKNK2 | 0.54685874 |
86 | SGK1 | 0.53068263 |
87 | CDK18 | 0.51245907 |
88 | PRKCZ | 0.51091360 |
89 | BRSK1 | 0.50896678 |
90 | FGFR2 | 0.49868012 |
91 | CAMK1 | 0.49630958 |
92 | PRKACA | 0.49316100 |
93 | PDPK1 | 0.49244048 |
94 | PRKCB | 0.48538679 |
95 | DAPK3 | 0.48063096 |
96 | DYRK1A | 0.45592340 |
97 | CSNK1G2 | 0.44800111 |
98 | LIMK1 | 0.44186972 |
99 | MAP2K1 | 0.43975393 |
100 | CDK3 | 0.42583335 |
101 | CDK15 | 0.42139724 |
102 | RPS6KA3 | 0.41520352 |
103 | RPS6KB1 | 0.40837976 |
104 | SCYL2 | 0.39738780 |
105 | ADRBK1 | 0.39439221 |
106 | PRKACB | 0.39419869 |
107 | ROCK2 | 0.38388547 |
108 | PNCK | 0.38386450 |
109 | NEK6 | 0.37829676 |
110 | BMPR1B | 0.37305429 |
111 | PRKCA | 0.36930089 |
112 | CSNK1G3 | 0.36466693 |
113 | MAP3K11 | 0.36163843 |
114 | MAP3K2 | 0.34489697 |
115 | FYN | 0.34230786 |
116 | CAMKK1 | 0.34090282 |
117 | KSR2 | 0.33275551 |
118 | RET | 0.33250254 |
119 | PRKG1 | 0.32960285 |
120 | STK39 | 0.32842358 |
121 | STK38 | 0.32462708 |
122 | MAP3K1 | 0.31998012 |
123 | PRKACG | 0.30934272 |
124 | LMTK2 | 0.29556103 |
125 | STK16 | 0.29399591 |
126 | CSNK1E | 0.25103330 |
127 | MAPK8 | 0.24334517 |
128 | CSNK1D | 0.24188626 |
129 | IRAK2 | 0.23951242 |
130 | SRC | 0.22427057 |
131 | TESK1 | 0.21972728 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 4.36530926 |
2 | Nicotine addiction_Homo sapiens_hsa05033 | 4.08429259 |
3 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 4.01961895 |
4 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 3.90347331 |
5 | GABAergic synapse_Homo sapiens_hsa04727 | 2.94211328 |
6 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.72824053 |
7 | Morphine addiction_Homo sapiens_hsa05032 | 2.47646257 |
8 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.37300261 |
9 | Olfactory transduction_Homo sapiens_hsa04740 | 2.15664364 |
10 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.15502789 |
11 | Long-term depression_Homo sapiens_hsa04730 | 2.08696624 |
12 | Circadian entrainment_Homo sapiens_hsa04713 | 2.08519557 |
13 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.95721385 |
14 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.93814492 |
15 | Taste transduction_Homo sapiens_hsa04742 | 1.93005653 |
16 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.88921798 |
17 | Long-term potentiation_Homo sapiens_hsa04720 | 1.82962011 |
18 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.68041127 |
19 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.65965927 |
20 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.65647845 |
21 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.59124883 |
22 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.58623160 |
23 | Salivary secretion_Homo sapiens_hsa04970 | 1.52183588 |
24 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.52132155 |
25 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.48723964 |
26 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.43308337 |
27 | Insulin secretion_Homo sapiens_hsa04911 | 1.43093243 |
28 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.41992002 |
29 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.40885923 |
30 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.36163992 |
31 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.31659476 |
32 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.31637199 |
33 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.18345280 |
34 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.10191614 |
35 | Phagosome_Homo sapiens_hsa04145 | 1.09703953 |
36 | Phototransduction_Homo sapiens_hsa04744 | 1.07533914 |
37 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.06202260 |
38 | Cocaine addiction_Homo sapiens_hsa05030 | 1.05938818 |
39 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.05117804 |
40 | Parkinsons disease_Homo sapiens_hsa05012 | 1.02594122 |
41 | Renin secretion_Homo sapiens_hsa04924 | 1.00836306 |
42 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.00641892 |
43 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.99387354 |
44 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.96333085 |
45 | Alzheimers disease_Homo sapiens_hsa05010 | 0.95701339 |
46 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.95311060 |
47 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.89651769 |
48 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.86594107 |
49 | Bile secretion_Homo sapiens_hsa04976 | 0.86094412 |
50 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.81501761 |
51 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.80992227 |
52 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.74933178 |
53 | Glioma_Homo sapiens_hsa05214 | 0.73149533 |
54 | Gap junction_Homo sapiens_hsa04540 | 0.72780888 |
55 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.71591409 |
56 | Prion diseases_Homo sapiens_hsa05020 | 0.69612163 |
57 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.67813054 |
58 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.67255987 |
59 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.66108979 |
60 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.63588265 |
61 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.62488008 |
62 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.61276920 |
63 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.60377684 |
64 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.60148380 |
65 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.59034662 |
66 | Melanoma_Homo sapiens_hsa05218 | 0.57719158 |
67 | Circadian rhythm_Homo sapiens_hsa04710 | 0.57717718 |
68 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.57625443 |
69 | Huntingtons disease_Homo sapiens_hsa05016 | 0.57268806 |
70 | Axon guidance_Homo sapiens_hsa04360 | 0.56285223 |
71 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.55647853 |
72 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.55452682 |
73 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.54886813 |
74 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.54699588 |
75 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.54222564 |
76 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.52951125 |
77 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.52813570 |
78 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.52011698 |
79 | Melanogenesis_Homo sapiens_hsa04916 | 0.48175396 |
80 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.47442562 |
81 | Alcoholism_Homo sapiens_hsa05034 | 0.45901580 |
82 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.45389988 |
83 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.42243447 |
84 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.41979314 |
85 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.41822061 |
86 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.41034427 |
87 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.40686385 |
88 | Mineral absorption_Homo sapiens_hsa04978 | 0.40071307 |
89 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.39892246 |
90 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.39863171 |
91 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.38885239 |
92 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.38041322 |
93 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.35877289 |
94 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.34483921 |
95 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.34044578 |
96 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.33656140 |
97 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.32968475 |
98 | Histidine metabolism_Homo sapiens_hsa00340 | 0.32525743 |
99 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.31856832 |
100 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.31692012 |
101 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.31172879 |
102 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.30417789 |
103 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.27948425 |
104 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.26606144 |
105 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.26508026 |
106 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.26417445 |
107 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.26076936 |
108 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.24547535 |
109 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.21904569 |
110 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.21412500 |
111 | Tight junction_Homo sapiens_hsa04530 | 0.19960578 |
112 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.19196875 |
113 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.18185736 |
114 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.17893143 |
115 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.17733501 |
116 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.16701339 |
117 | Endocytosis_Homo sapiens_hsa04144 | 0.15813610 |
118 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.15802735 |
119 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.15153870 |
120 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.14426443 |
121 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.13155587 |
122 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.11714506 |