SYT17

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.49888793
2regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.27208848
3vocalization behavior (GO:0071625)5.26870962
4neuron cell-cell adhesion (GO:0007158)5.26702017
5synaptic vesicle exocytosis (GO:0016079)5.21572034
6glutamate secretion (GO:0014047)4.98147557
7dopamine transport (GO:0015872)4.97171413
8ionotropic glutamate receptor signaling pathway (GO:0035235)4.86685291
9regulation of glutamate receptor signaling pathway (GO:1900449)4.83443403
10protein localization to synapse (GO:0035418)4.64121021
11dopamine biosynthetic process (GO:0042416)4.62896490
12positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.57556609
13catecholamine transport (GO:0051937)4.44396924
14positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.43295164
15regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.41959922
16synaptic vesicle maturation (GO:0016188)4.38593012
17glutamate receptor signaling pathway (GO:0007215)4.36441904
18regulation of synaptic vesicle exocytosis (GO:2000300)4.24716270
19locomotory exploration behavior (GO:0035641)4.22328091
20synaptic transmission, glutamatergic (GO:0035249)4.17577124
21neuron-neuron synaptic transmission (GO:0007270)4.11803652
22exploration behavior (GO:0035640)4.08198835
23neurotransmitter secretion (GO:0007269)4.07815856
24regulation of long-term neuronal synaptic plasticity (GO:0048169)4.02898117
25regulation of neuronal synaptic plasticity (GO:0048168)4.00401086
26neuron recognition (GO:0008038)3.99777992
27regulation of synaptic vesicle transport (GO:1902803)3.87413992
28negative regulation of cytosolic calcium ion concentration (GO:0051481)3.81012485
29synaptic vesicle docking involved in exocytosis (GO:0016081)3.78506678
30regulation of excitatory postsynaptic membrane potential (GO:0060079)3.70236927
31neurotransmitter transport (GO:0006836)3.63051691
32regulation of vesicle fusion (GO:0031338)3.61975240
33dendritic spine morphogenesis (GO:0060997)3.61695192
34phenol-containing compound catabolic process (GO:0019336)3.61631882
35synaptic vesicle endocytosis (GO:0048488)3.60260651
36membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.59212540
37regulation of postsynaptic membrane potential (GO:0060078)3.56882838
38negative regulation of synaptic transmission, GABAergic (GO:0032229)3.56868339
39gamma-aminobutyric acid signaling pathway (GO:0007214)3.54469537
40neuronal action potential propagation (GO:0019227)3.53283277
41neurotransmitter-gated ion channel clustering (GO:0072578)3.51457998
42response to amphetamine (GO:0001975)3.51042214
43axonal fasciculation (GO:0007413)3.47981901
44postsynaptic membrane organization (GO:0001941)3.47954290
45positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.46152368
46regulation of neurotransmitter levels (GO:0001505)3.44230988
47long-term memory (GO:0007616)3.42617819
48regulation of dopamine metabolic process (GO:0042053)3.39633806
49regulation of catecholamine metabolic process (GO:0042069)3.39633806
50proline transport (GO:0015824)3.39450745
51nonmotile primary cilium assembly (GO:0035058)3.38940942
52gamma-aminobutyric acid transport (GO:0015812)3.37058038
53regulation of synapse structural plasticity (GO:0051823)3.35358653
54regulation of synaptic plasticity (GO:0048167)3.33644716
55presynaptic membrane assembly (GO:0097105)3.33229828
56long-term synaptic potentiation (GO:0060291)3.31634924
57behavioral response to nicotine (GO:0035095)3.29795825
58innervation (GO:0060384)3.29703783
59positive regulation of synapse assembly (GO:0051965)3.29600329
60cellular ketone body metabolic process (GO:0046950)3.29441996
61positive regulation of neurotransmitter transport (GO:0051590)3.29000734
62neuromuscular synaptic transmission (GO:0007274)3.27553840
63regulation of neurotransmitter secretion (GO:0046928)3.26904750
64response to histamine (GO:0034776)3.26837711
65positive regulation of neurotransmitter secretion (GO:0001956)3.26154160
66synaptic transmission, dopaminergic (GO:0001963)3.24761937
67pyrimidine nucleobase catabolic process (GO:0006208)3.24145911
68regulation of glutamate secretion (GO:0014048)3.20239112
69mating behavior (GO:0007617)3.19140454
70regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.19082029
71transmission of nerve impulse (GO:0019226)3.17066664
72G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.15877495
73nucleobase catabolic process (GO:0046113)3.14998613
74regulation of neurotransmitter transport (GO:0051588)3.14508343
75regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.14044484
76regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.13601574
77fear response (GO:0042596)3.11634784
78regulation of synaptic transmission, glutamatergic (GO:0051966)3.08686970
79catecholamine biosynthetic process (GO:0042423)3.08665312
80catechol-containing compound biosynthetic process (GO:0009713)3.08665312
81response to cocaine (GO:0042220)3.06944563
82membrane depolarization (GO:0051899)3.06682737
83G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.06332962
84reflex (GO:0060004)3.06105803
85negative regulation of neurotransmitter transport (GO:0051589)3.05665988
86synaptic transmission (GO:0007268)3.05624572
87behavioral fear response (GO:0001662)3.04698457
88behavioral defense response (GO:0002209)3.04698457
89positive regulation of membrane potential (GO:0045838)3.04324394
90establishment of synaptic vesicle localization (GO:0097480)3.03535649
91synaptic vesicle transport (GO:0048489)3.03535649
92epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.01173700
93opioid receptor signaling pathway (GO:0038003)3.00518270
94righting reflex (GO:0060013)2.99927578
95prepulse inhibition (GO:0060134)2.99665047
96mechanosensory behavior (GO:0007638)2.99294867
97presynaptic membrane organization (GO:0097090)2.98636534
98learning (GO:0007612)2.97970055
99dopamine metabolic process (GO:0042417)2.96305745
100regulation of dendritic spine morphogenesis (GO:0061001)2.95191085
101auditory behavior (GO:0031223)2.94769546
102positive regulation of synapse maturation (GO:0090129)2.94744926
103synapse assembly (GO:0007416)2.94662836
104primary amino compound metabolic process (GO:1901160)2.92939837
105regulation of synapse assembly (GO:0051963)2.92818012
106ketone body metabolic process (GO:1902224)2.92071321
107response to auditory stimulus (GO:0010996)2.91949904
108positive regulation of dendritic spine morphogenesis (GO:0061003)2.91795499
109positive regulation of meiosis (GO:0045836)2.91621932
110positive regulation of dendritic spine development (GO:0060999)2.91525424
111serotonin metabolic process (GO:0042428)2.91348845
112behavioral response to cocaine (GO:0048148)2.90956995
113detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.90871158
114regulation of respiratory gaseous exchange (GO:0043576)2.90864128
115startle response (GO:0001964)2.88993944
116cilium movement (GO:0003341)2.86403387
117epithelial cilium movement (GO:0003351)2.86323238
118regulation of neurotransmitter uptake (GO:0051580)2.83501804
119neuron fate determination (GO:0048664)2.82655061
120protein localization to cilium (GO:0061512)2.80056396
121dopaminergic neuron differentiation (GO:0071542)2.77774632
122indole-containing compound catabolic process (GO:0042436)2.77283919
123indolalkylamine catabolic process (GO:0046218)2.77283919
124tryptophan catabolic process (GO:0006569)2.77283919
125retinal ganglion cell axon guidance (GO:0031290)2.74544268
126nephron tubule morphogenesis (GO:0072078)2.74101144
127nephron epithelium morphogenesis (GO:0072088)2.74101144
128detection of light stimulus involved in sensory perception (GO:0050962)2.73804646
129detection of light stimulus involved in visual perception (GO:0050908)2.73804646
130axon ensheathment in central nervous system (GO:0032291)2.72995045
131central nervous system myelination (GO:0022010)2.72995045
132retinal cone cell development (GO:0046549)2.71683458
133positive regulation of meiotic cell cycle (GO:0051446)2.69986824
134indolalkylamine metabolic process (GO:0006586)2.69511630
135regulation of respiratory system process (GO:0044065)2.67836993
136regulation of calcium ion-dependent exocytosis (GO:0017158)2.66265566
137cochlea development (GO:0090102)2.64301579
138negative regulation of astrocyte differentiation (GO:0048712)2.59569651
139kidney morphogenesis (GO:0060993)2.59394534
140cilium organization (GO:0044782)2.58884350
141potassium ion transmembrane transport (GO:0071805)2.58637671
142cellular potassium ion transport (GO:0071804)2.58637671
143positive regulation of gastrulation (GO:2000543)2.58410706
144cilium assembly (GO:0042384)2.57070992
145regulation of action potential (GO:0098900)2.55147696
146membrane depolarization during action potential (GO:0086010)2.54494720
147behavioral response to ethanol (GO:0048149)2.54094643
148indole-containing compound metabolic process (GO:0042430)2.53427793
149neuronal action potential (GO:0019228)2.52694301
150glycerophospholipid catabolic process (GO:0046475)2.49592463
151C4-dicarboxylate transport (GO:0015740)2.44444860
152potassium ion transport (GO:0006813)2.41700285
153axoneme assembly (GO:0035082)2.40768474
154retina layer formation (GO:0010842)2.40586690
155intraciliary transport (GO:0042073)2.39841377
156renal tubule morphogenesis (GO:0061333)2.39608426
157urinary tract smooth muscle contraction (GO:0014848)2.38669191

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.61336703
2GBX2_23144817_ChIP-Seq_PC3_Human4.10478406
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.13831409
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.99799417
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.99280124
6SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.75187056
7SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.63304459
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.57078123
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.57078123
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.56829468
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.52087527
12* REST_21632747_ChIP-Seq_MESCs_Mouse2.44873242
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.44743000
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.37763444
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.33208412
16CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.31526919
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.31116462
18ZFP57_27257070_Chip-Seq_ESCs_Mouse2.21877155
19TAF15_26573619_Chip-Seq_HEK293_Human2.17396367
20IGF1R_20145208_ChIP-Seq_DFB_Human2.13959758
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.12951201
22* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.10047982
23IKZF1_21737484_ChIP-ChIP_HCT116_Human2.09963361
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.09749519
25DROSHA_22980978_ChIP-Seq_HELA_Human2.09684332
26HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.08064046
27* EZH2_27294783_Chip-Seq_ESCs_Mouse2.06538691
28CTBP2_25329375_ChIP-Seq_LNCAP_Human1.97675422
29CTBP1_25329375_ChIP-Seq_LNCAP_Human1.96101567
30TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.91849785
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.88427450
32* REST_18959480_ChIP-ChIP_MESCs_Mouse1.87371467
33RARB_27405468_Chip-Seq_BRAIN_Mouse1.87058709
34P300_19829295_ChIP-Seq_ESCs_Human1.86144290
35SMAD4_21799915_ChIP-Seq_A2780_Human1.83754308
36BMI1_23680149_ChIP-Seq_NPCS_Mouse1.79756842
37SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.71693273
38GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.71050936
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.67824838
40CBX2_27304074_Chip-Seq_ESCs_Mouse1.61385453
41PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.58152957
42POU3F2_20337985_ChIP-ChIP_501MEL_Human1.55538246
43BCAT_22108803_ChIP-Seq_LS180_Human1.53818100
44ZNF274_21170338_ChIP-Seq_K562_Hela1.53630210
45FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.53619983
46* NR3C1_23031785_ChIP-Seq_PC12_Mouse1.52623074
47AR_21572438_ChIP-Seq_LNCaP_Human1.48953538
48VDR_22108803_ChIP-Seq_LS180_Human1.47178396
49PIAS1_25552417_ChIP-Seq_VCAP_Human1.46653019
50AR_25329375_ChIP-Seq_VCAP_Human1.44314993
51TOP2B_26459242_ChIP-Seq_MCF-7_Human1.42988613
52RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.41696066
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.37625975
54MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.36394788
55RNF2_27304074_Chip-Seq_NSC_Mouse1.35928654
56ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.35212522
57SMAD_19615063_ChIP-ChIP_OVARY_Human1.34744880
58SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34401644
59CBP_20019798_ChIP-Seq_JUKART_Human1.33432460
60IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.33432460
61FUS_26573619_Chip-Seq_HEK293_Human1.31668023
62CDX2_19796622_ChIP-Seq_MESCs_Mouse1.27000772
63ERG_21242973_ChIP-ChIP_JURKAT_Human1.24645817
64CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24573621
65OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24143442
66TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.23672236
67UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.23297374
68SOX2_21211035_ChIP-Seq_LN229_Gbm1.22893496
69STAT3_23295773_ChIP-Seq_U87_Human1.20778547
70SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.17508888
71POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.17160221
72TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17160221
73PCGF2_27294783_Chip-Seq_NPCs_Mouse1.16479864
74MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.15937950
75TCF4_22108803_ChIP-Seq_LS180_Human1.15846004
76AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.15338810
77* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.14492302
78PRDM14_20953172_ChIP-Seq_ESCs_Human1.13851008
79NANOG_18555785_Chip-Seq_ESCs_Mouse1.13842825
80TP53_16413492_ChIP-PET_HCT116_Human1.13318491
81* RING1B_27294783_Chip-Seq_ESCs_Mouse1.13043077
82RUNX2_22187159_ChIP-Seq_PCA_Human1.12353880
83NFE2_27457419_Chip-Seq_LIVER_Mouse1.11879043
84TCF4_23295773_ChIP-Seq_U87_Human1.09656754
85AR_19668381_ChIP-Seq_PC3_Human1.09241958
86TP53_18474530_ChIP-ChIP_U2OS_Human1.09083038
87NR3C1_21868756_ChIP-Seq_MCF10A_Human1.08322532
88TP53_22573176_ChIP-Seq_HFKS_Human1.08025173
89SOX2_19829295_ChIP-Seq_ESCs_Human1.07151478
90NANOG_19829295_ChIP-Seq_ESCs_Human1.07151478
91EWS_26573619_Chip-Seq_HEK293_Human1.06257617
92JUN_21703547_ChIP-Seq_K562_Human1.05356789
93ER_23166858_ChIP-Seq_MCF-7_Human1.05099772
94* SMAD4_21741376_ChIP-Seq_EPCs_Human1.03540109
95EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.03482655
96EZH2_27294783_Chip-Seq_NPCs_Mouse1.03282390
97LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03115791
98KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.02725223
99KLF5_20875108_ChIP-Seq_MESCs_Mouse1.02345628
100CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.01600189
101EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.99854184
102ARNT_22903824_ChIP-Seq_MCF-7_Human0.98942497
103E2F1_18555785_Chip-Seq_ESCs_Mouse0.98652275
104TAL1_26923725_Chip-Seq_HPCs_Mouse0.98337322
105PCGF2_27294783_Chip-Seq_ESCs_Mouse0.97535773
106AHR_22903824_ChIP-Seq_MCF-7_Human0.95178430
107P53_22387025_ChIP-Seq_ESCs_Mouse0.95165491
108YAP1_20516196_ChIP-Seq_MESCs_Mouse0.95015350
109P53_22127205_ChIP-Seq_FIBROBLAST_Human0.94055706
110CMYC_18555785_Chip-Seq_ESCs_Mouse0.93091254
111FLI1_27457419_Chip-Seq_LIVER_Mouse0.92886949
112RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.92160801
113ZNF217_24962896_ChIP-Seq_MCF-7_Human0.92107512
114MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91873361
115MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.90947148
116TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90892082
117BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.90785097
118SMAD4_21741376_ChIP-Seq_HESCs_Human0.90725921
119SUZ12_27294783_Chip-Seq_NPCs_Mouse0.89916711

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.18529761
2MP0003880_abnormal_central_pattern5.58089830
3MP0003635_abnormal_synaptic_transmissio3.95439679
4MP0009745_abnormal_behavioral_response3.44917093
5MP0002063_abnormal_learning/memory/cond3.24627443
6MP0002822_catalepsy3.20909254
7MP0002064_seizures3.05827312
8MP0006276_abnormal_autonomic_nervous2.91669438
9MP0002572_abnormal_emotion/affect_behav2.79216765
10MP0001968_abnormal_touch/_nociception2.77011582
11MP0004270_analgesia2.74838753
12MP0009046_muscle_twitch2.69297314
13MP0001905_abnormal_dopamine_level2.68733299
14MP0001501_abnormal_sleep_pattern2.63801509
15MP0002735_abnormal_chemical_nociception2.48358485
16MP0002736_abnormal_nociception_after2.47079445
17MP0002272_abnormal_nervous_system2.39560412
18MP0001440_abnormal_grooming_behavior2.39407334
19MP0005423_abnormal_somatic_nervous2.32706164
20MP0000566_synostosis2.32472333
21MP0001486_abnormal_startle_reflex2.32012974
22MP0001529_abnormal_vocalization2.30465992
23MP0002734_abnormal_mechanical_nocicepti2.20309555
24MP0005646_abnormal_pituitary_gland2.08574300
25MP0003195_calcinosis2.07170292
26MP0001188_hyperpigmentation2.03226822
27MP0008877_abnormal_DNA_methylation1.94277033
28MP0000778_abnormal_nervous_system1.91706509
29MP0002733_abnormal_thermal_nociception1.91488521
30MP0002184_abnormal_innervation1.90210580
31MP0002067_abnormal_sensory_capabilities1.88477117
32MP0001970_abnormal_pain_threshold1.84752071
33MP0003122_maternal_imprinting1.84515574
34MP0006072_abnormal_retinal_apoptosis1.81124430
35MP0005386_behavior/neurological_phenoty1.76466846
36MP0004924_abnormal_behavior1.76466846
37MP0005645_abnormal_hypothalamus_physiol1.74642905
38MP0002557_abnormal_social/conspecific_i1.74038599
39MP0005084_abnormal_gallbladder_morpholo1.67050851
40MP0003283_abnormal_digestive_organ1.64629550
41MP0002653_abnormal_ependyma_morphology1.63375599
42MP0010386_abnormal_urinary_bladder1.63055032
43MP0004043_abnormal_pH_regulation1.59999529
44MP0003787_abnormal_imprinting1.54718516
45MP0004133_heterotaxia1.50548381
46MP0004811_abnormal_neuron_physiology1.48276542
47MP0003136_yellow_coat_color1.47510856
48MP0003011_delayed_dark_adaptation1.44958881
49MP0001984_abnormal_olfaction1.44788413
50MP0002938_white_spotting1.44278134
51MP0004858_abnormal_nervous_system1.43704902
52MP0001485_abnormal_pinna_reflex1.42541762
53MP0002638_abnormal_pupillary_reflex1.40507989
54MP0002876_abnormal_thyroid_physiology1.39544950
55MP0002909_abnormal_adrenal_gland1.39074001
56MP0000955_abnormal_spinal_cord1.38343195
57MP0001502_abnormal_circadian_rhythm1.36861166
58MP0008875_abnormal_xenobiotic_pharmacok1.35953691
59MP0005253_abnormal_eye_physiology1.34054383
60MP0008569_lethality_at_weaning1.33529386
61MP0002882_abnormal_neuron_morphology1.30967759
62MP0002139_abnormal_hepatobiliary_system1.30074386
63MP0005409_darkened_coat_color1.29711814
64MP0002066_abnormal_motor_capabilities/c1.29494854
65MP0003329_amyloid_beta_deposits1.28621893
66MP0008961_abnormal_basal_metabolism1.26302981
67MP0008872_abnormal_physiological_respon1.22592276
68MP0001944_abnormal_pancreas_morphology1.18524921
69MP0001986_abnormal_taste_sensitivity1.16612652
70MP0003879_abnormal_hair_cell1.13968769
71MP0002928_abnormal_bile_duct1.13895580
72MP0003631_nervous_system_phenotype1.11358727
73MP0006292_abnormal_olfactory_placode1.10411900
74MP0003633_abnormal_nervous_system1.07703597
75MP0004142_abnormal_muscle_tone1.02590095
76MP0001664_abnormal_digestion1.02383599
77MP0005171_absent_coat_pigmentation1.02015567
78MP0003632_abnormal_nervous_system1.00691312
79MP0009780_abnormal_chondrocyte_physiolo0.99816574
80MP0005535_abnormal_body_temperature0.98382338
81MP0002837_dystrophic_cardiac_calcinosis0.98047411
82MP0005448_abnormal_energy_balance0.97633032
83MP0002152_abnormal_brain_morphology0.97592441
84MP0002102_abnormal_ear_morphology0.95041087
85MP0002069_abnormal_eating/drinking_beha0.93391754
86MP0002751_abnormal_autonomic_nervous0.91635101
87MP0000751_myopathy0.88430353
88MP0001963_abnormal_hearing_physiology0.88362484
89MP0005551_abnormal_eye_electrophysiolog0.87858177
90MP0000631_abnormal_neuroendocrine_gland0.86911299
91MP0000383_abnormal_hair_follicle0.85005718
92MP0003890_abnormal_embryonic-extraembry0.84619969
93MP0002693_abnormal_pancreas_physiology0.84295394
94MP0005195_abnormal_posterior_eye0.84148226
95MP0004742_abnormal_vestibular_system0.84056744
96MP0003938_abnormal_ear_development0.83376821
97MP0005394_taste/olfaction_phenotype0.82963029
98MP0005499_abnormal_olfactory_system0.82963029
99MP0000427_abnormal_hair_cycle0.82287768
100MP0002138_abnormal_hepatobiliary_system0.81897731
101MP0002752_abnormal_somatic_nervous0.81828138
102MP0000538_abnormal_urinary_bladder0.81149253
103MP0000569_abnormal_digit_pigmentation0.80969031
104MP0005085_abnormal_gallbladder_physiolo0.80791506
105MP0005377_hearing/vestibular/ear_phenot0.79750247
106MP0003878_abnormal_ear_physiology0.79750247
107MP0004145_abnormal_muscle_electrophysio0.74114485
108MP0002229_neurodegeneration0.73717900
109MP0004484_altered_response_of0.73533282
110MP0004085_abnormal_heartbeat0.72654778
111MP0008874_decreased_physiological_sensi0.70972042
112MP0004510_myositis0.70898932
113MP0002090_abnormal_vision0.67911254
114MP0001177_atelectasis0.67731513
115MP0000026_abnormal_inner_ear0.66248095
116MP0003121_genomic_imprinting0.63698613
117MP0002163_abnormal_gland_morphology0.62556205
118MP0004885_abnormal_endolymph0.62555974
119MP0001299_abnormal_eye_distance/0.56668124
120MP0000681_abnormal_thyroid_gland0.56550884
121MP0003634_abnormal_glial_cell0.54869336
122MP0005379_endocrine/exocrine_gland_phen0.54533576
123MP0005248_abnormal_Harderian_gland0.53774353
124MP0004215_abnormal_myocardial_fiber0.51318367
125MP0003123_paternal_imprinting0.50641679
126MP0000015_abnormal_ear_pigmentation0.50083544
127MP0001943_abnormal_respiration0.50049295
128MP0008260_abnormal_autophagy0.47414509
129MP0001346_abnormal_lacrimal_gland0.46232985
130MP0002234_abnormal_pharynx_morphology0.46161316
131MP0010770_preweaning_lethality0.45763123

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.17874234
2Myokymia (HP:0002411)6.53073748
3Limb dystonia (HP:0002451)5.74842153
4Focal seizures (HP:0007359)5.53598494
5Visual hallucinations (HP:0002367)5.25733927
6Epileptic encephalopathy (HP:0200134)4.84861325
7Febrile seizures (HP:0002373)4.77605492
8Hypothermia (HP:0002045)4.40846751
9Progressive cerebellar ataxia (HP:0002073)4.36248623
10Atonic seizures (HP:0010819)4.27903778
11Nephronophthisis (HP:0000090)3.89161409
12Hyperventilation (HP:0002883)3.86401517
13Generalized tonic-clonic seizures (HP:0002069)3.86212089
14Absence seizures (HP:0002121)3.72626653
15Pancreatic cysts (HP:0001737)3.62649952
16Dialeptic seizures (HP:0011146)3.60267237
17Broad-based gait (HP:0002136)3.54488607
18Molar tooth sign on MRI (HP:0002419)3.53809494
19Abnormality of midbrain morphology (HP:0002418)3.53809494
20Pancreatic fibrosis (HP:0100732)3.43052566
21Amblyopia (HP:0000646)3.42999132
22True hermaphroditism (HP:0010459)3.40831822
23Abnormality of the renal medulla (HP:0100957)3.21341752
24Progressive inability to walk (HP:0002505)3.11453727
25Gaze-evoked nystagmus (HP:0000640)3.01528880
26Action tremor (HP:0002345)3.00918048
27Pheochromocytoma (HP:0002666)2.97206940
28Exotropia (HP:0000577)2.95177571
29Congenital stationary night blindness (HP:0007642)2.91309241
30Truncal ataxia (HP:0002078)2.89244496
31Anxiety (HP:0000739)2.86268942
32Poor eye contact (HP:0000817)2.83631458
33Depression (HP:0000716)2.83061120
34Failure to thrive in infancy (HP:0001531)2.81410474
35Type II lissencephaly (HP:0007260)2.78865832
36Dysdiadochokinesis (HP:0002075)2.74852748
37Absent speech (HP:0001344)2.74435624
38Tubular atrophy (HP:0000092)2.74189310
39Inability to walk (HP:0002540)2.72838321
40Drooling (HP:0002307)2.72609462
41Excessive salivation (HP:0003781)2.72609462
42Delusions (HP:0000746)2.67076039
43Abnormality of the renal cortex (HP:0011035)2.62502195
44Polydipsia (HP:0001959)2.60578835
45Abnormal drinking behavior (HP:0030082)2.60578835
46Dysmetria (HP:0001310)2.57847603
47Neuroendocrine neoplasm (HP:0100634)2.55086392
48Epileptiform EEG discharges (HP:0011182)2.54196643
49Hypoventilation (HP:0002791)2.52702020
50Abnormal hair whorl (HP:0010721)2.50905401
51Abnormal eating behavior (HP:0100738)2.50537090
52Abnormal respiratory motile cilium physiology (HP:0012261)2.49738854
53Supranuclear gaze palsy (HP:0000605)2.48845700
54Cerebral inclusion bodies (HP:0100314)2.48352875
55Polyuria (HP:0000103)2.46180504
56Large for gestational age (HP:0001520)2.45554587
57Abnormal respiratory epithelium morphology (HP:0012253)2.44995577
58Abnormal respiratory motile cilium morphology (HP:0005938)2.44995577
59Chronic hepatic failure (HP:0100626)2.34470110
60EEG with generalized epileptiform discharges (HP:0011198)2.34193070
61Protruding tongue (HP:0010808)2.32633815
62Mutism (HP:0002300)2.32379739
63Impaired social interactions (HP:0000735)2.31105777
64Abnormal social behavior (HP:0012433)2.31105777
65Diplopia (HP:0000651)2.30838441
66Abnormality of binocular vision (HP:0011514)2.30838441
67Cystic liver disease (HP:0006706)2.29513710
68Bradykinesia (HP:0002067)2.27792608
69Polyphagia (HP:0002591)2.27767793
70Gait imbalance (HP:0002141)2.27644965
71Fetal akinesia sequence (HP:0001989)2.26058479
72Intestinal atresia (HP:0011100)2.19880505
73Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.18806355
74Hypsarrhythmia (HP:0002521)2.16663179
75Attenuation of retinal blood vessels (HP:0007843)2.15578262
76Oligodactyly (hands) (HP:0001180)2.15552636
77Orthostatic hypotension (HP:0001278)2.12303938
78Hemiparesis (HP:0001269)2.11961943
79Congenital sensorineural hearing impairment (HP:0008527)2.11576106
80Incomplete penetrance (HP:0003829)2.11407611
81Abnormality of the labia minora (HP:0012880)2.10568450
82Hypomagnesemia (HP:0002917)2.08831595
83Nephrogenic diabetes insipidus (HP:0009806)2.07142572
84Abnormal urine output (HP:0012590)2.04808017
85Medial flaring of the eyebrow (HP:0010747)2.04610065
86Rhinitis (HP:0012384)2.03476127
87Congenital hepatic fibrosis (HP:0002612)2.03364954
88Impaired vibration sensation in the lower limbs (HP:0002166)2.02923634
89Abnormality of salivation (HP:0100755)2.01927377
90Palpebral edema (HP:0100540)2.01183509
91Concave nail (HP:0001598)1.99778886
92Congenital primary aphakia (HP:0007707)1.99770258
93Genital tract atresia (HP:0001827)1.99555216
94Abnormal autonomic nervous system physiology (HP:0012332)1.98190272
95Blue irides (HP:0000635)1.97280596
96Retinal dysplasia (HP:0007973)1.96730564
97Dynein arm defect of respiratory motile cilia (HP:0012255)1.95450684
98Absent/shortened dynein arms (HP:0200106)1.95450684
99Decreased central vision (HP:0007663)1.94332012
100Lissencephaly (HP:0001339)1.94113643
101Gastroesophageal reflux (HP:0002020)1.94015210
102Abnormal rod and cone electroretinograms (HP:0008323)1.93872335
103Ankle clonus (HP:0011448)1.93303613
104Vaginal atresia (HP:0000148)1.92757005
105Aplasia/Hypoplasia of the tongue (HP:0010295)1.92522886
106Cerebellar dysplasia (HP:0007033)1.91001465
107Severe muscular hypotonia (HP:0006829)1.90608040
108Sclerocornea (HP:0000647)1.90476451
109Abnormal ciliary motility (HP:0012262)1.90316565
110Agitation (HP:0000713)1.90065296
111Focal dystonia (HP:0004373)1.88922521
112Impaired smooth pursuit (HP:0007772)1.88727343
113Torticollis (HP:0000473)1.88597272
114Poor coordination (HP:0002370)1.87849129
115Dyskinesia (HP:0100660)1.87792757
116Stereotypic behavior (HP:0000733)1.87750517
117Postaxial hand polydactyly (HP:0001162)1.86219595
118Esotropia (HP:0000565)1.85832143
119Urinary bladder sphincter dysfunction (HP:0002839)1.84381963
120Abnormality of renal excretion (HP:0011036)1.83555837
121Postural instability (HP:0002172)1.83341235
122Male pseudohermaphroditism (HP:0000037)1.83306210
123Abnormality of aromatic amino acid family metabolism (HP:0004338)1.82190822
124Aplasia/Hypoplasia of the tibia (HP:0005772)1.81920189
125Delayed gross motor development (HP:0002194)1.80914861
126Bony spicule pigmentary retinopathy (HP:0007737)1.79306972
127Gastrointestinal atresia (HP:0002589)1.78989730
128Optic nerve hypoplasia (HP:0000609)1.78540108
129Specific learning disability (HP:0001328)1.78458980
130Ketoacidosis (HP:0001993)1.77793468
131Abnormal EKG (HP:0003115)1.77367343
132Glycosuria (HP:0003076)1.77275546
133Abnormality of urine glucose concentration (HP:0011016)1.77275546
134Gait ataxia (HP:0002066)1.76878971
135Abnormality of renal resorption (HP:0011038)1.76100582
136Heterochromia iridis (HP:0001100)1.75282248
137Syncope (HP:0001279)1.75261264
138Delayed CNS myelination (HP:0002188)1.74757592
139Abnormality of ocular smooth pursuit (HP:0000617)1.74312024
140Anencephaly (HP:0002323)1.74257794
141Fair hair (HP:0002286)1.73823099
142Neurofibrillary tangles (HP:0002185)1.73657509
143Psychosis (HP:0000709)1.72914672
144Furrowed tongue (HP:0000221)1.72797992
145Aplasia/Hypoplasia of the lens (HP:0008063)1.72356325
146Progressive macrocephaly (HP:0004481)1.72221617
147Muscular hypotonia of the trunk (HP:0008936)1.71248096
148Rigidity (HP:0002063)1.69787245
149Status epilepticus (HP:0002133)1.69772573
150Tubulointerstitial abnormality (HP:0001969)1.69099989
151Narrow nasal bridge (HP:0000446)1.67159918
152Abnormality of calcium-phosphate metabolism (HP:0100530)1.66729923
153Bradycardia (HP:0001662)1.66494929
154Abnormality of the lower motor neuron (HP:0002366)1.66148661
155Generalized myoclonic seizures (HP:0002123)1.66006906
156Aplasia/Hypoplasia of the brainstem (HP:0007362)1.65924761
157Hypoplasia of the brainstem (HP:0002365)1.65924761
158Poor suck (HP:0002033)1.64415226

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.88701662
2FRK4.56441642
3PRPF4B4.48966043
4EPHA43.85385455
5MAP3K93.33465187
6MAP3K123.11422829
7MAP2K72.71395398
8MINK12.57853828
9MAP3K42.52597507
10CASK2.49940733
11GRK52.22765906
12PLK22.21261699
13MARK12.18377349
14FGFR22.12848182
15SIK32.11420056
16TAOK22.05732142
17RIPK42.02863985
18GRK12.02781518
19DAPK21.98080327
20ARAF1.92969601
21DAPK11.87256208
22KSR11.79456345
23MAP2K41.68283426
24MAP4K21.66923041
25NTRK21.62904241
26PTK2B1.50584927
27ZAK1.49084359
28WNK41.43608593
29STK38L1.42129246
30PNCK1.41887100
31TNIK1.38217321
32UHMK11.36193711
33STK391.35031744
34MAP3K131.34693914
35MAPK131.34200265
36CDK51.29040512
37NTRK11.27836997
38CAMK2A1.26999037
39KSR21.26712829
40GRK71.26191658
41PRKCG1.23622256
42TLK11.22027431
43PAK61.19174344
44MAP2K61.18240155
45BMPR21.13855515
46CAMK2B1.13373078
47FGR1.13209061
48BCR1.11493375
49MAPK151.06347950
50PINK11.06315585
51NME11.03883709
52FES1.03188075
53TRIM280.99850784
54MKNK20.98589248
55MAPKAPK50.98137251
56CSNK1G20.97946791
57MST40.95575195
58DYRK20.95243312
59CDK180.94604870
60ACVR1B0.93356834
61CSNK1G30.85236269
62SIK20.83259714
63TGFBR10.82053967
64CDK150.82024820
65DYRK1A0.80281723
66EPHA30.80124124
67ADRBK20.79964051
68STK30.78945579
69EPHB20.78024328
70CDK140.75889832
71PKN10.74146582
72CAMK10.73267358
73CAMKK10.72698017
74CAMK2D0.71236709
75LATS20.70163283
76CDK11A0.70116129
77PRKCE0.68442384
78NUAK10.68303850
79PAK30.66300948
80OXSR10.62292172
81FER0.62229782
82CDK190.61454536
83MUSK0.59724034
84GRK60.59491892
85STK380.58724892
86CAMK2G0.57004420
87CAMK1G0.56750494
88CCNB10.55851956
89RAF10.55134488
90WNK30.53912053
91SGK4940.53442871
92SGK2230.53442871
93ERBB30.52753778
94CAMKK20.52625454
95PRKD30.52389578
96TIE10.52162799
97PRKG10.51504578
98ERBB20.51455781
99CSNK1G10.51118363
100ADRBK10.50898201
101BRAF0.47969605
102PHKG10.47363091
103PHKG20.47363091
104CSNK1A1L0.45949916
105MAP2K10.45744405
106AKT30.45482132
107SGK10.45395715
108MAP3K20.44467201
109CDK30.43061663
110MAPKAPK30.42927445
111SGK20.42767319
112TNK20.41528315
113CSNK1D0.40514539
114TAOK30.40353875
115MOS0.38973355
116PRKAA10.38189090
117ROCK10.38156989
118MAP3K10.37056279
119PRKACB0.35817562
120STK110.34452138
121PRKCZ0.34443620
122RET0.34111037
123TYRO30.34094455
124PASK0.33345579
125MAPK70.33115046
126BMPR1B0.32609011
127PRKACA0.32241370
128INSRR0.31408920
129SYK0.31060429
130YES10.30054969
131NEK60.28868060
132RPS6KA30.27449353
133PRKCH0.26833921
134CSNK1A10.26742855
135PRKCA0.26169137
136TSSK60.25635954

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.30621516
2Synaptic vesicle cycle_Homo sapiens_hsa047213.60310948
3Amphetamine addiction_Homo sapiens_hsa050312.93469852
4Maturity onset diabetes of the young_Homo sapiens_hsa049502.93262666
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.82804352
6Circadian entrainment_Homo sapiens_hsa047132.63569344
7Long-term potentiation_Homo sapiens_hsa047202.59174776
8Glutamatergic synapse_Homo sapiens_hsa047242.59139663
9GABAergic synapse_Homo sapiens_hsa047272.55495871
10Olfactory transduction_Homo sapiens_hsa047402.54594204
11Collecting duct acid secretion_Homo sapiens_hsa049662.47450617
12Morphine addiction_Homo sapiens_hsa050322.41905792
13Dopaminergic synapse_Homo sapiens_hsa047282.39963740
14Serotonergic synapse_Homo sapiens_hsa047262.23026800
15Cocaine addiction_Homo sapiens_hsa050302.22777444
16Butanoate metabolism_Homo sapiens_hsa006502.18313835
17Taste transduction_Homo sapiens_hsa047422.11307343
18Salivary secretion_Homo sapiens_hsa049702.02129814
19Cholinergic synapse_Homo sapiens_hsa047251.99957966
20Linoleic acid metabolism_Homo sapiens_hsa005911.93313019
21Insulin secretion_Homo sapiens_hsa049111.86404110
22Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.80795678
23Calcium signaling pathway_Homo sapiens_hsa040201.75650147
24Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.69463345
25Long-term depression_Homo sapiens_hsa047301.69192691
26Renin secretion_Homo sapiens_hsa049241.65039968
27Caffeine metabolism_Homo sapiens_hsa002321.62626570
28Gastric acid secretion_Homo sapiens_hsa049711.60514824
29Oxytocin signaling pathway_Homo sapiens_hsa049211.58659697
30alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.58247222
31Oxidative phosphorylation_Homo sapiens_hsa001901.55954606
32Tryptophan metabolism_Homo sapiens_hsa003801.55615415
33Vibrio cholerae infection_Homo sapiens_hsa051101.51586456
34Aldosterone synthesis and secretion_Homo sapiens_hsa049251.49880607
35Primary bile acid biosynthesis_Homo sapiens_hsa001201.41427847
36GnRH signaling pathway_Homo sapiens_hsa049121.39582702
37Protein export_Homo sapiens_hsa030601.38448045
38Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.35430505
39Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.30111886
40Parkinsons disease_Homo sapiens_hsa050121.29271790
41Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.28487309
42Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.26786531
43Alzheimers disease_Homo sapiens_hsa050101.22849107
44Gap junction_Homo sapiens_hsa045401.21287702
45Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.19914841
46Axon guidance_Homo sapiens_hsa043601.19846825
47Cardiac muscle contraction_Homo sapiens_hsa042601.19772393
48Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.19542309
49Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.19466309
50beta-Alanine metabolism_Homo sapiens_hsa004101.13450276
51Ether lipid metabolism_Homo sapiens_hsa005651.11295321
52Phototransduction_Homo sapiens_hsa047441.08668216
53Nitrogen metabolism_Homo sapiens_hsa009101.08591919
54cAMP signaling pathway_Homo sapiens_hsa040241.07028526
55Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.05148287
56Bile secretion_Homo sapiens_hsa049761.04984222
57Histidine metabolism_Homo sapiens_hsa003401.03480462
58Chemical carcinogenesis_Homo sapiens_hsa052041.02183955
59Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.00335102
60Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.00199684
61ABC transporters_Homo sapiens_hsa020100.98273384
62Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.97892799
63Folate biosynthesis_Homo sapiens_hsa007900.97599024
64Retinol metabolism_Homo sapiens_hsa008300.97275666
65Steroid hormone biosynthesis_Homo sapiens_hsa001400.97195650
66Phosphatidylinositol signaling system_Homo sapiens_hsa040700.97164447
67Rheumatoid arthritis_Homo sapiens_hsa053230.96401081
68Sulfur metabolism_Homo sapiens_hsa009200.93953015
69Melanogenesis_Homo sapiens_hsa049160.92551723
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.91976634
71cGMP-PKG signaling pathway_Homo sapiens_hsa040220.89228900
72African trypanosomiasis_Homo sapiens_hsa051430.88755262
73ErbB signaling pathway_Homo sapiens_hsa040120.88202636
74Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.86410329
75Peroxisome_Homo sapiens_hsa041460.85799312
76Estrogen signaling pathway_Homo sapiens_hsa049150.83507621
77Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.82804255
78Type II diabetes mellitus_Homo sapiens_hsa049300.82099308
79Selenocompound metabolism_Homo sapiens_hsa004500.78507952
80Propanoate metabolism_Homo sapiens_hsa006400.78303173
81Vascular smooth muscle contraction_Homo sapiens_hsa042700.77492673
82Huntingtons disease_Homo sapiens_hsa050160.76043851
83Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.74958849
84Hedgehog signaling pathway_Homo sapiens_hsa043400.74840040
85Glioma_Homo sapiens_hsa052140.73353507
86Arachidonic acid metabolism_Homo sapiens_hsa005900.70418225
87Pancreatic secretion_Homo sapiens_hsa049720.69929882
88Type I diabetes mellitus_Homo sapiens_hsa049400.67455155
89Pentose and glucuronate interconversions_Homo sapiens_hsa000400.64665409
90Basal transcription factors_Homo sapiens_hsa030220.64609673
91Alcoholism_Homo sapiens_hsa050340.62127179
92Dilated cardiomyopathy_Homo sapiens_hsa054140.61831282
93Prion diseases_Homo sapiens_hsa050200.61606694
94Dorso-ventral axis formation_Homo sapiens_hsa043200.61268393
95Phagosome_Homo sapiens_hsa041450.60397259
96Oocyte meiosis_Homo sapiens_hsa041140.59671776
97MAPK signaling pathway_Homo sapiens_hsa040100.58431163
98Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.57981793
99Phospholipase D signaling pathway_Homo sapiens_hsa040720.57970812
100Choline metabolism in cancer_Homo sapiens_hsa052310.57757680
101Ras signaling pathway_Homo sapiens_hsa040140.54876148
102Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.52933797
103Basal cell carcinoma_Homo sapiens_hsa052170.52580632
104Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52213835
105Thyroid hormone synthesis_Homo sapiens_hsa049180.51007941
106Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49875093
107Fatty acid elongation_Homo sapiens_hsa000620.49599650
108Inositol phosphate metabolism_Homo sapiens_hsa005620.47711585
109Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.47479333
110Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47222074
111Vitamin B6 metabolism_Homo sapiens_hsa007500.46302798
112Fat digestion and absorption_Homo sapiens_hsa049750.46105632
113SNARE interactions in vesicular transport_Homo sapiens_hsa041300.45899146
114Glucagon signaling pathway_Homo sapiens_hsa049220.45528893
115Rap1 signaling pathway_Homo sapiens_hsa040150.44843949
116Arginine and proline metabolism_Homo sapiens_hsa003300.44336782
117Wnt signaling pathway_Homo sapiens_hsa043100.44060017
118Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.42562797
119RNA polymerase_Homo sapiens_hsa030200.39893378
120Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.39396515
121VEGF signaling pathway_Homo sapiens_hsa043700.38853892
122Regulation of autophagy_Homo sapiens_hsa041400.38684065
123Steroid biosynthesis_Homo sapiens_hsa001000.35753114
124Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.35448876
125Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.34905387
126Phenylalanine metabolism_Homo sapiens_hsa003600.34659329
127Neurotrophin signaling pathway_Homo sapiens_hsa047220.34600544
128Sphingolipid signaling pathway_Homo sapiens_hsa040710.33025806
129Tyrosine metabolism_Homo sapiens_hsa003500.32658489
130Chemokine signaling pathway_Homo sapiens_hsa040620.28216459
131Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.27338869
132Circadian rhythm_Homo sapiens_hsa047100.27054769
133Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.25418709
134Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.25339617
135Ovarian steroidogenesis_Homo sapiens_hsa049130.24584850
136Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.23306709
137Tuberculosis_Homo sapiens_hsa051520.21085709
138Salmonella infection_Homo sapiens_hsa051320.19679416
139Endocytosis_Homo sapiens_hsa041440.19504842
140Thyroid hormone signaling pathway_Homo sapiens_hsa049190.18908736
141Mineral absorption_Homo sapiens_hsa049780.18906703
142Carbohydrate digestion and absorption_Homo sapiens_hsa049730.17917174

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