SYT9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)7.18624931
2central nervous system myelination (GO:0022010)7.18624931
3* positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.53983768
4regulation of short-term neuronal synaptic plasticity (GO:0048172)5.49631892
5synaptic vesicle maturation (GO:0016188)5.17901390
6cerebral cortex neuron differentiation (GO:0021895)4.98944352
7response to pheromone (GO:0019236)4.80335246
8regulation of synaptic vesicle exocytosis (GO:2000300)4.59526726
9cell migration in hindbrain (GO:0021535)4.45701180
10proline transport (GO:0015824)4.37448331
11synaptic vesicle exocytosis (GO:0016079)4.35087889
12glutamate secretion (GO:0014047)4.32566272
13cellular potassium ion homeostasis (GO:0030007)4.32288553
14layer formation in cerebral cortex (GO:0021819)4.30031829
15regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.22977361
16negative regulation of oligodendrocyte differentiation (GO:0048715)4.13205230
17locomotory exploration behavior (GO:0035641)4.02084963
18cerebellar Purkinje cell differentiation (GO:0021702)4.00602197
19postsynaptic membrane organization (GO:0001941)3.98973279
20pyrimidine nucleobase catabolic process (GO:0006208)3.98113779
21membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.97809466
22neuromuscular process controlling posture (GO:0050884)3.97025082
23protein localization to synapse (GO:0035418)3.93401309
24positive regulation of synaptic transmission, GABAergic (GO:0032230)3.92793043
25neurotransmitter secretion (GO:0007269)3.90522886
26neurotransmitter-gated ion channel clustering (GO:0072578)3.88907125
27negative regulation of microtubule polymerization (GO:0031115)3.88435010
28negative regulation of astrocyte differentiation (GO:0048712)3.87858928
29detection of temperature stimulus involved in sensory perception of pain (GO:0050965)3.87202653
30detection of temperature stimulus involved in sensory perception (GO:0050961)3.87202653
31regulation of synaptic vesicle transport (GO:1902803)3.86302718
32detection of temperature stimulus (GO:0016048)3.85686284
33positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.76839589
34synaptic vesicle docking involved in exocytosis (GO:0016081)3.67633985
35mating behavior (GO:0007617)3.67169324
36neuronal action potential propagation (GO:0019227)3.64972016
37positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.64516243
38axon cargo transport (GO:0008088)3.60988970
39neuronal ion channel clustering (GO:0045161)3.58814670
40presynaptic membrane assembly (GO:0097105)3.56299815
41presynaptic membrane organization (GO:0097090)3.54948114
42neuron cell-cell adhesion (GO:0007158)3.54552574
43sodium ion export (GO:0071436)3.54155524
44membrane depolarization during action potential (GO:0086010)3.50445727
45innervation (GO:0060384)3.48524392
46cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.42872097
47vocalization behavior (GO:0071625)3.42715176
48regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.39992164
49auditory behavior (GO:0031223)3.38893303
50positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.38628123
51neuroblast proliferation (GO:0007405)3.38282897
52positive regulation of synapse maturation (GO:0090129)3.34236584
53neurotransmitter transport (GO:0006836)3.33171318
54adult walking behavior (GO:0007628)3.29564107
55vesicle transport along microtubule (GO:0047496)3.28888757
56establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.28467083
57mitochondrion transport along microtubule (GO:0047497)3.28467083
58gamma-aminobutyric acid transport (GO:0015812)3.28282524
59nucleobase catabolic process (GO:0046113)3.26374070
60potassium ion homeostasis (GO:0055075)3.25336878
61behavioral response to cocaine (GO:0048148)3.23844169
62synaptic vesicle endocytosis (GO:0048488)3.23366349
63cell differentiation in hindbrain (GO:0021533)3.21963913
64organelle transport along microtubule (GO:0072384)3.21791479
65negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.19798225
66regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.13728951
67synaptic transmission, glutamatergic (GO:0035249)3.13701459
68neuromuscular synaptic transmission (GO:0007274)3.13192858
69cerebellar granule cell differentiation (GO:0021707)3.11744476
70positive regulation of potassium ion transmembrane transport (GO:1901381)3.10969467
71exploration behavior (GO:0035640)3.10917497
72neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.10337908
73activation of protein kinase A activity (GO:0034199)3.08918561
74establishment of mitochondrion localization (GO:0051654)3.08643327
75behavioral response to ethanol (GO:0048149)3.07929314
76negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.07358746
77neuronal action potential (GO:0019228)3.06982937
78neuromuscular process controlling balance (GO:0050885)3.06976607
79cell communication by electrical coupling (GO:0010644)3.05989508
80regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.04312310
81neuron-neuron synaptic transmission (GO:0007270)3.02045991
82membrane repolarization (GO:0086009)3.01384740
83membrane hyperpolarization (GO:0060081)3.00095004
84regulation of neurotransmitter secretion (GO:0046928)2.98555945
85regulation of vesicle fusion (GO:0031338)2.94484330
86long-term memory (GO:0007616)2.93451664
87regulation of long-term neuronal synaptic plasticity (GO:0048169)2.91857770
88dendrite morphogenesis (GO:0048813)2.89685547
89response to auditory stimulus (GO:0010996)2.89619042
90glycine transport (GO:0015816)2.89566478
91negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.88419459
92response to pain (GO:0048265)2.88117626
93ionotropic glutamate receptor signaling pathway (GO:0035235)2.88019156
94G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.87765647
95cell differentiation involved in metanephros development (GO:0072202)2.86676831
96dendritic spine organization (GO:0097061)2.85126741
97glutamate receptor signaling pathway (GO:0007215)2.84718790
98cochlea development (GO:0090102)2.82487443
99histone H2B ubiquitination (GO:0033523)2.82143442
100regulation of neurotransmitter levels (GO:0001505)2.81845912
101regulation of synaptic transmission, glutamatergic (GO:0051966)2.80183461
102cell communication involved in cardiac conduction (GO:0086065)2.79561058
103negative regulation of hormone biosynthetic process (GO:0032353)2.79232087
104L-amino acid import (GO:0043092)2.78847890
105regulation of neuronal synaptic plasticity (GO:0048168)2.78415593
106central nervous system projection neuron axonogenesis (GO:0021952)2.78176075
107regulation of clathrin-mediated endocytosis (GO:2000369)2.78166486
108synapse assembly (GO:0007416)2.76868489
109axonal fasciculation (GO:0007413)2.76445184
110gamma-aminobutyric acid signaling pathway (GO:0007214)2.75637197
111behavioral response to nicotine (GO:0035095)2.75322519
112* regulation of calcium ion-dependent exocytosis (GO:0017158)2.73796838
113regulation of glutamate receptor signaling pathway (GO:1900449)2.72701225
114regulation of neurotransmitter transport (GO:0051588)2.71587461
115neuromuscular process (GO:0050905)2.71072247
116negative regulation of synaptic transmission, GABAergic (GO:0032229)2.69757716
117phosphorelay signal transduction system (GO:0000160)2.69065770
118embryonic retina morphogenesis in camera-type eye (GO:0060059)2.69065770
119neuron recognition (GO:0008038)2.66785562
120transmission of nerve impulse (GO:0019226)2.65879481
121negative regulation of glial cell differentiation (GO:0045686)2.65487554
122regulation of glycogen (starch) synthase activity (GO:2000465)2.64733026
123neurofilament cytoskeleton organization (GO:0060052)2.64715860
124urinary tract smooth muscle contraction (GO:0014848)2.63880757
125regulation of postsynaptic membrane potential (GO:0060078)2.63852715
126mechanosensory behavior (GO:0007638)2.63574541
127regulation of respiratory system process (GO:0044065)2.63321663
128positive regulation of potassium ion transport (GO:0043268)2.62587435
129positive regulation of membrane potential (GO:0045838)2.61333612
130dendritic spine morphogenesis (GO:0060997)2.61198844
131cytoskeleton-dependent intracellular transport (GO:0030705)2.60527151
132dopamine receptor signaling pathway (GO:0007212)2.59237513
133retinal cone cell development (GO:0046549)2.59146451
134chemosensory behavior (GO:0007635)2.58861537
135microtubule-based transport (GO:0010970)2.58192189
136calcium ion-dependent exocytosis (GO:0017156)2.58163821
137synaptic transmission (GO:0007268)2.57937713
138righting reflex (GO:0060013)2.57272179
139startle response (GO:0001964)2.56282802
140long-chain fatty acid biosynthetic process (GO:0042759)2.56131774
141regulation of synapse structural plasticity (GO:0051823)2.54651332
142regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.53514143
143suckling behavior (GO:0001967)2.50555233
144microtubule severing (GO:0051013)2.48093616
145behavioral defense response (GO:0002209)2.47603929
146behavioral fear response (GO:0001662)2.47603929
147regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.45207614
148regulation of dopamine secretion (GO:0014059)2.44889115
149myelination (GO:0042552)2.43233923

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.00474186
2* REST_21632747_ChIP-Seq_MESCs_Mouse2.85167269
3NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.61734538
4ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.53921627
5EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.52510530
6* REST_18959480_ChIP-ChIP_MESCs_Mouse2.50911264
7GBX2_23144817_ChIP-Seq_PC3_Human2.28126342
8RARB_27405468_Chip-Seq_BRAIN_Mouse2.24588130
9SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.24377783
10SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.21548855
11SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.17329643
12CBX2_27304074_Chip-Seq_ESCs_Mouse2.16560146
13CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.15869301
14TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.09674870
15ERG_21242973_ChIP-ChIP_JURKAT_Human2.07302258
16JARID2_20064375_ChIP-Seq_MESCs_Mouse2.05044077
17KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.01118601
18KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.01118601
19KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.01118601
20JARID2_20075857_ChIP-Seq_MESCs_Mouse1.99519156
21RNF2_18974828_ChIP-Seq_MESCs_Mouse1.95433656
22EZH2_18974828_ChIP-Seq_MESCs_Mouse1.95433656
23SALL1_21062744_ChIP-ChIP_HESCs_Human1.92965993
24ZNF263_19887448_ChIP-Seq_K562_Human1.92648127
25SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.89611602
26GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.88732808
27DROSHA_22980978_ChIP-Seq_HELA_Human1.87681542
28SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.85108072
29ZFP281_18757296_ChIP-ChIP_E14_Mouse1.83355097
30NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.82801265
31MTF2_20144788_ChIP-Seq_MESCs_Mouse1.80731928
32* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.78185767
33ZFP57_27257070_Chip-Seq_ESCs_Mouse1.73530349
34SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.72560828
35EZH2_27304074_Chip-Seq_ESCs_Mouse1.71774442
36TAF15_26573619_Chip-Seq_HEK293_Human1.68696823
37RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.65573872
38CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.64691599
39MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.64056247
40SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.60027383
41EZH2_27294783_Chip-Seq_ESCs_Mouse1.59773943
42ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.59181232
43PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.58995415
44ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.58138797
45P300_19829295_ChIP-Seq_ESCs_Human1.56684239
46SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.55761362
47RNF2_27304074_Chip-Seq_ESCs_Mouse1.54443049
48TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.53240597
49POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.50619254
50TOP2B_26459242_ChIP-Seq_MCF-7_Human1.47035441
51SUZ12_27294783_Chip-Seq_ESCs_Mouse1.46884809
52BMI1_23680149_ChIP-Seq_NPCS_Mouse1.45384776
53KDM2B_26808549_Chip-Seq_K562_Human1.45064152
54SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.44493636
55IKZF1_21737484_ChIP-ChIP_HCT116_Human1.44089712
56RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.44058980
57SMAD3_21741376_ChIP-Seq_EPCs_Human1.43882506
58TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42300827
59EED_16625203_ChIP-ChIP_MESCs_Mouse1.42249275
60CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.41822492
61SMAD4_21799915_ChIP-Seq_A2780_Human1.41759758
62FUS_26573619_Chip-Seq_HEK293_Human1.39834519
63NR3C1_23031785_ChIP-Seq_PC12_Mouse1.38567103
64TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38413881
65POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.38413881
66PIAS1_25552417_ChIP-Seq_VCAP_Human1.37603501
67AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.37451249
68* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.37155086
69ZNF274_21170338_ChIP-Seq_K562_Hela1.36464034
70ESR1_15608294_ChIP-ChIP_MCF-7_Human1.36421322
71CTBP2_25329375_ChIP-Seq_LNCAP_Human1.36308644
72ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.36173931
73POU3F2_20337985_ChIP-ChIP_501MEL_Human1.32207496
74ZFP281_27345836_Chip-Seq_ESCs_Mouse1.30702268
75MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.29017510
76NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.28000764
77SOX2_21211035_ChIP-Seq_LN229_Gbm1.26749263
78* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.26606286
79SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.26099859
80GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26020054
81* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.25412428
82LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23682437
83AR_19668381_ChIP-Seq_PC3_Human1.23339248
84NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.23200211
85RBPJ_22232070_ChIP-Seq_NCS_Mouse1.22798935
86RING1B_27294783_Chip-Seq_NPCs_Mouse1.22766069
87RNF2_27304074_Chip-Seq_NSC_Mouse1.22653357
88* STAT3_23295773_ChIP-Seq_U87_Human1.21649186
89CDX2_19796622_ChIP-Seq_MESCs_Mouse1.20430768
90RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.20187879
91TBX3_20139965_ChIP-Seq_MESCs_Mouse1.19828665
92TBX3_20139965_ChIP-Seq_ESCs_Mouse1.18195667
93STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.17489765
94IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.16789520
95CBP_20019798_ChIP-Seq_JUKART_Human1.16789520
96EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.16212847
97HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.14714401
98YAP1_20516196_ChIP-Seq_MESCs_Mouse1.14294038
99CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13917123
100GATA1_26923725_Chip-Seq_HPCs_Mouse1.13880385
101UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.12653334
102NR3C1_21868756_ChIP-Seq_MCF10A_Human1.12584105
103POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.12468925
104AR_25329375_ChIP-Seq_VCAP_Human1.11963575
105SMAD3_21741376_ChIP-Seq_ESCs_Human1.11906725
106TET1_21490601_ChIP-Seq_MESCs_Mouse1.11259614
107EP300_21415370_ChIP-Seq_HL-1_Mouse1.10768557
108* POU5F1_16518401_ChIP-PET_MESCs_Mouse1.10485549
109CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.09513523
110RUNX2_22187159_ChIP-Seq_PCA_Human1.08710212
111OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.08416632
112SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.07021861
113CTCF_27219007_Chip-Seq_Bcells_Human1.06820508
114RING1B_27294783_Chip-Seq_ESCs_Mouse1.05126641
115AR_21572438_ChIP-Seq_LNCaP_Human1.04555897
116PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.03636623
117SMAD4_21741376_ChIP-Seq_HESCs_Human1.03140766
118TCF3_18692474_ChIP-Seq_MESCs_Mouse1.02515305
119TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.02018035
120TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.01380655
121JUN_21703547_ChIP-Seq_K562_Human1.00559539
122SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.99309565
123MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99100719
124NANOG_18555785_Chip-Seq_ESCs_Mouse0.98923762
125TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.98627352
126DNAJC2_21179169_ChIP-ChIP_NT2_Human0.98568618
127PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.98162346
128P53_22127205_ChIP-Seq_FIBROBLAST_Human0.97594724
129CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.97453621
130DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.97396681
131TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.97199552
132* NANOG_16518401_ChIP-PET_MESCs_Mouse0.96554941
133TP53_16413492_ChIP-PET_HCT116_Human0.95710524
134POU5F1_16153702_ChIP-ChIP_HESCs_Human0.95285926
135TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.95188936
136WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.94807772
137VDR_22108803_ChIP-Seq_LS180_Human0.94275086
138* TCF4_23295773_ChIP-Seq_U87_Human0.94031879
139CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.93921944
140* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.93800110
141ZNF217_24962896_ChIP-Seq_MCF-7_Human0.93201259
142IGF1R_20145208_ChIP-Seq_DFB_Human0.92761500
143* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.91213022
144FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.89898771
145OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.89233113

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004270_analgesia3.81689647
2MP0001968_abnormal_touch/_nociception3.72595727
3MP0004859_abnormal_synaptic_plasticity3.68786073
4MP0002735_abnormal_chemical_nociception3.55570843
5MP0002734_abnormal_mechanical_nocicepti3.22990097
6MP0003635_abnormal_synaptic_transmissio2.86143434
7MP0002733_abnormal_thermal_nociception2.84988182
8MP0002736_abnormal_nociception_after2.73351347
9MP0009046_muscle_twitch2.59424106
10MP0005423_abnormal_somatic_nervous2.51743259
11MP0003880_abnormal_central_pattern2.48343056
12MP0004858_abnormal_nervous_system2.47708453
13MP0001970_abnormal_pain_threshold2.47148684
14MP0006276_abnormal_autonomic_nervous2.44261681
15MP0002272_abnormal_nervous_system2.34821511
16MP0003136_yellow_coat_color2.32909118
17MP0006072_abnormal_retinal_apoptosis2.32872757
18MP0002184_abnormal_innervation2.16983902
19MP0002063_abnormal_learning/memory/cond2.16550851
20MP0009745_abnormal_behavioral_response2.16118182
21MP0002064_seizures2.11346786
22MP0005551_abnormal_eye_electrophysiolog2.05696659
23MP0010386_abnormal_urinary_bladder2.00020458
24MP0002572_abnormal_emotion/affect_behav1.99024778
25MP0002067_abnormal_sensory_capabilities1.97010308
26MP0002638_abnormal_pupillary_reflex1.86340216
27MP0001440_abnormal_grooming_behavior1.79906285
28MP0002139_abnormal_hepatobiliary_system1.78773252
29MP0000566_synostosis1.73013975
30MP0003283_abnormal_digestive_organ1.72177472
31MP0002909_abnormal_adrenal_gland1.71175793
32MP0005253_abnormal_eye_physiology1.69325424
33MP0000955_abnormal_spinal_cord1.69139944
34MP0000778_abnormal_nervous_system1.60373200
35MP0001986_abnormal_taste_sensitivity1.59931371
36MP0001486_abnormal_startle_reflex1.58991360
37MP0003787_abnormal_imprinting1.56443864
38MP0004811_abnormal_neuron_physiology1.55601270
39MP0004885_abnormal_endolymph1.53696721
40MP0002882_abnormal_neuron_morphology1.50658898
41MP0004924_abnormal_behavior1.50118445
42MP0005386_behavior/neurological_phenoty1.50118445
43MP0003122_maternal_imprinting1.48514109
44MP0002822_catalepsy1.48374568
45MP0008569_lethality_at_weaning1.46099365
46MP0004145_abnormal_muscle_electrophysio1.42399804
47MP0002557_abnormal_social/conspecific_i1.41461499
48MP0001984_abnormal_olfaction1.41407474
49MP0001529_abnormal_vocalization1.40407598
50MP0005645_abnormal_hypothalamus_physiol1.39822109
51MP0002653_abnormal_ependyma_morphology1.38690323
52MP0008877_abnormal_DNA_methylation1.37413600
53MP0001485_abnormal_pinna_reflex1.36697275
54MP0002229_neurodegeneration1.36622078
55MP0003690_abnormal_glial_cell1.35704806
56MP0002234_abnormal_pharynx_morphology1.35028521
57MP0001501_abnormal_sleep_pattern1.33344138
58MP0001293_anophthalmia1.29753022
59MP0003123_paternal_imprinting1.29626826
60MP0002751_abnormal_autonomic_nervous1.29592443
61MP0005394_taste/olfaction_phenotype1.26070049
62MP0005499_abnormal_olfactory_system1.26070049
63MP0005646_abnormal_pituitary_gland1.21918384
64MP0002752_abnormal_somatic_nervous1.18049537
65MP0002066_abnormal_motor_capabilities/c1.17980068
66MP0003890_abnormal_embryonic-extraembry1.13588176
67MP0001502_abnormal_circadian_rhythm1.12477195
68MP0004142_abnormal_muscle_tone1.08950225
69MP0002152_abnormal_brain_morphology1.08714675
70MP0003329_amyloid_beta_deposits1.04081190
71MP0001299_abnormal_eye_distance/1.00042845
72MP0003633_abnormal_nervous_system0.99288620
73MP0005187_abnormal_penis_morphology0.97504676
74MP0002938_white_spotting0.96272554
75MP0003121_genomic_imprinting0.95701790
76MP0000372_irregular_coat_pigmentation0.95280457
77MP0003942_abnormal_urinary_system0.93992345
78MP0000631_abnormal_neuroendocrine_gland0.92763255
79MP0003011_delayed_dark_adaptation0.92051092
80MP0000013_abnormal_adipose_tissue0.91060613
81MP0000026_abnormal_inner_ear0.90650282
82MP0003632_abnormal_nervous_system0.90196457
83MP0004233_abnormal_muscle_weight0.90066200
84MP0003631_nervous_system_phenotype0.89746202
85MP0002102_abnormal_ear_morphology0.89002221
86MP0003879_abnormal_hair_cell0.88740343
87MP0003634_abnormal_glial_cell0.88446318
88MP0003861_abnormal_nervous_system0.88255950
89MP0003137_abnormal_impulse_conducting0.86224176
90MP0000049_abnormal_middle_ear0.85944077
91MP0000534_abnormal_ureter_morphology0.84073620
92MP0002928_abnormal_bile_duct0.84014178
93MP0001188_hyperpigmentation0.82827426
94MP0008789_abnormal_olfactory_epithelium0.82092815
95MP0000920_abnormal_myelination0.81771466
96MP0003183_abnormal_peptide_metabolism0.81109929
97MP0002090_abnormal_vision0.80350814
98MP0009780_abnormal_chondrocyte_physiolo0.79986887
99MP0004215_abnormal_myocardial_fiber0.79578349
100MP0008872_abnormal_physiological_respon0.77356786
101MP0002697_abnormal_eye_size0.77229778
102MP0004133_heterotaxia0.77147571
103MP0005365_abnormal_bile_salt0.76652665
104MP0005085_abnormal_gallbladder_physiolo0.76405301
105MP0003878_abnormal_ear_physiology0.75068126
106MP0005377_hearing/vestibular/ear_phenot0.75068126
107MP0010234_abnormal_vibrissa_follicle0.74609818
108MP0004742_abnormal_vestibular_system0.74460544
109MP0005195_abnormal_posterior_eye0.72364157
110MP0005623_abnormal_meninges_morphology0.70428471
111MP0003119_abnormal_digestive_system0.70255563
112MP0008961_abnormal_basal_metabolism0.69135714
113MP0000569_abnormal_digit_pigmentation0.68908754
114MP0002877_abnormal_melanocyte_morpholog0.67942982
115MP0005391_vision/eye_phenotype0.67561229
116MP0001348_abnormal_lacrimal_gland0.66354020
117MP0005171_absent_coat_pigmentation0.65743879
118MP0002069_abnormal_eating/drinking_beha0.64002450
119MP0001963_abnormal_hearing_physiology0.63331600
120MP0001905_abnormal_dopamine_level0.63007286
121MP0000747_muscle_weakness0.61249085
122MP0003698_abnormal_male_reproductive0.60126038
123MP0006292_abnormal_olfactory_placode0.58197234

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.01298855
2Visual hallucinations (HP:0002367)4.36370873
3Action tremor (HP:0002345)4.35871609
4Progressive cerebellar ataxia (HP:0002073)3.95597082
5Focal seizures (HP:0007359)3.81276221
6Hyperventilation (HP:0002883)3.78820907
7Focal motor seizures (HP:0011153)3.39471453
8Abnormality of the lower motor neuron (HP:0002366)3.36820534
9Atonic seizures (HP:0010819)3.36431786
10Congenital stationary night blindness (HP:0007642)3.32448884
11Absence seizures (HP:0002121)3.23231516
12Termporal pattern (HP:0011008)3.08085657
13Insidious onset (HP:0003587)3.08085657
14Ankle clonus (HP:0011448)3.06318415
15Febrile seizures (HP:0002373)2.99250543
16Epileptic encephalopathy (HP:0200134)2.95870091
17Tubulointerstitial nephritis (HP:0001970)2.94337289
18Dialeptic seizures (HP:0011146)2.84240841
19Pheochromocytoma (HP:0002666)2.82737109
20Cutaneous finger syndactyly (HP:0010554)2.82239756
21Neurofibrillary tangles (HP:0002185)2.75606312
22Ulnar claw (HP:0001178)2.71316374
23Generalized tonic-clonic seizures (HP:0002069)2.66940751
24Degeneration of the lateral corticospinal tracts (HP:0002314)2.66794478
25Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.66794478
26Supranuclear gaze palsy (HP:0000605)2.66411723
27Abnormality of the corticospinal tract (HP:0002492)2.66097489
28Agitation (HP:0000713)2.63738501
29Septo-optic dysplasia (HP:0100842)2.59978631
30Central scotoma (HP:0000603)2.59496604
31Truncal ataxia (HP:0002078)2.55674844
32Abnormality of pain sensation (HP:0010832)2.51333660
33Impaired pain sensation (HP:0007328)2.51333660
34Depression (HP:0000716)2.49445864
35Dysdiadochokinesis (HP:0002075)2.48386770
36Postural tremor (HP:0002174)2.48175629
37Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.47092623
38Midline defect of the nose (HP:0004122)2.40594234
39Urinary bladder sphincter dysfunction (HP:0002839)2.40077715
40Dysautonomia (HP:0002459)2.39715518
41Anophthalmia (HP:0000528)2.39418962
42Limb dystonia (HP:0002451)2.39343636
43Genetic anticipation (HP:0003743)2.35736406
44Neuroendocrine neoplasm (HP:0100634)2.34023860
45Abnormality of the astrocytes (HP:0100707)2.33966599
46Astrocytoma (HP:0009592)2.33966599
47Gaze-evoked nystagmus (HP:0000640)2.32902772
48Cutaneous syndactyly (HP:0012725)2.32173209
49Bony spicule pigmentary retinopathy (HP:0007737)2.29589943
50Morphological abnormality of the middle ear (HP:0008609)2.26190542
51Double outlet right ventricle (HP:0001719)2.25782685
52Congenital malformation of the right heart (HP:0011723)2.25782685
53Amyotrophic lateral sclerosis (HP:0007354)2.25646089
54Orthostatic hypotension (HP:0001278)2.25410257
55Gait imbalance (HP:0002141)2.24368307
56Vaginal atresia (HP:0000148)2.24286682
57Impaired smooth pursuit (HP:0007772)2.24245791
58Abnormal biliary tract physiology (HP:0012439)2.23191480
59Bile duct proliferation (HP:0001408)2.23191480
60Horizontal nystagmus (HP:0000666)2.23066430
61Hypercortisolism (HP:0001578)2.22109497
62Hypoventilation (HP:0002791)2.21089800
63Spastic gait (HP:0002064)2.20134588
64Genital tract atresia (HP:0001827)2.20074924
65Failure to thrive in infancy (HP:0001531)2.20060022
66Abnormal eating behavior (HP:0100738)2.18264101
67Hypothermia (HP:0002045)2.17390225
68EEG with generalized epileptiform discharges (HP:0011198)2.16916110
69Cerebral inclusion bodies (HP:0100314)2.16188019
70Optic nerve hypoplasia (HP:0000609)2.15771040
71Polyphagia (HP:0002591)2.15440543
72Morphological abnormality of the pyramidal tract (HP:0002062)2.15040659
73Amblyopia (HP:0000646)2.13750768
74Macroorchidism (HP:0000053)2.12846273
75Abnormal autonomic nervous system physiology (HP:0012332)2.12601153
76Abnormality of macular pigmentation (HP:0008002)2.12414661
77Abnormality of ocular smooth pursuit (HP:0000617)2.11175533
78Ependymoma (HP:0002888)2.11152022
79Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.10886472
80Menstrual irregularities (HP:0000858)2.09859526
81Abnormality of the labia minora (HP:0012880)2.09696871
82Myelomeningocele (HP:0002475)2.08717512
83Clonus (HP:0002169)2.08134952
84Broad distal phalanx of finger (HP:0009836)2.07511858
85Insomnia (HP:0100785)2.06842893
86Epileptiform EEG discharges (HP:0011182)2.06796985
87Scotoma (HP:0000575)2.06613395
88Poor eye contact (HP:0000817)2.06438276
89Lower limb muscle weakness (HP:0007340)2.05479442
90Papilledema (HP:0001085)2.03465203
91Urinary urgency (HP:0000012)2.01404669
92Dysmetria (HP:0001310)2.00464941
93Hand muscle atrophy (HP:0009130)2.00334544
94Mutism (HP:0002300)1.98333855
95Abnormality of calcium-phosphate metabolism (HP:0100530)1.98055388
96Anxiety (HP:0000739)1.97025082
97Maternal diabetes (HP:0009800)1.96844791
98True hermaphroditism (HP:0010459)1.96704146
99Neoplasm of the peripheral nervous system (HP:0100007)1.95979725
100Hypsarrhythmia (HP:0002521)1.95844350
101Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.93172987
102Bicornuate uterus (HP:0000813)1.93002212
103Aqueductal stenosis (HP:0002410)1.92217732
104Hemiparesis (HP:0001269)1.89979375
105Ventricular fibrillation (HP:0001663)1.89943839
106Impaired vibration sensation in the lower limbs (HP:0002166)1.89900163
107Status epilepticus (HP:0002133)1.89870476
108Renal hypoplasia (HP:0000089)1.89548453
109Abnormal social behavior (HP:0012433)1.88825687
110Impaired social interactions (HP:0000735)1.88825687
111Excessive salivation (HP:0003781)1.88479883
112Drooling (HP:0002307)1.88479883
113Pancreatic fibrosis (HP:0100732)1.88264389
114Dyschromatopsia (HP:0007641)1.87275860
115Dysmetric saccades (HP:0000641)1.87196777
116Myotonia (HP:0002486)1.85762843
117Postural instability (HP:0002172)1.84214902
118Scanning speech (HP:0002168)1.82956030
119Congenital primary aphakia (HP:0007707)1.80938869
120Tetraplegia (HP:0002445)1.80791233
121Broad-based gait (HP:0002136)1.80333343
122Abnormal rod and cone electroretinograms (HP:0008323)1.79978397
123Thyroid carcinoma (HP:0002890)1.79015461
124Apathy (HP:0000741)1.78824867
125Esophageal atresia (HP:0002032)1.78742695
126Neuroblastoma (HP:0003006)1.78006070
127Primitive neuroectodermal tumor (HP:0030065)1.78006070
128Neuroblastic tumors (HP:0004376)1.78006070
129Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.78006070
130Medial flaring of the eyebrow (HP:0010747)1.76180680
131Hemiplegia (HP:0002301)1.75315718
132Supernumerary spleens (HP:0009799)1.73641186
133Nephronophthisis (HP:0000090)1.73616260
134Hammertoe (HP:0001765)1.73271884
135Intention tremor (HP:0002080)1.72878274
136Type II diabetes mellitus (HP:0005978)1.71076727
137Specific learning disability (HP:0001328)1.70657459
138Cortical dysplasia (HP:0002539)1.69831252
139Absent septum pellucidum (HP:0001331)1.69108320
140Testicular neoplasm (HP:0010788)1.69104450
141Anencephaly (HP:0002323)1.68249126
142Generalized myoclonic seizures (HP:0002123)1.66332153
143Impulsivity (HP:0100710)1.65341169
144Torticollis (HP:0000473)1.64450113
145Turricephaly (HP:0000262)1.63940747
146Abnormality of dentin (HP:0010299)1.63673364
147Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.63058490
148Poor coordination (HP:0002370)1.59054581
149Pancreatic cysts (HP:0001737)1.58123632
150Diminished motivation (HP:0000745)1.56730665
151Large for gestational age (HP:0001520)1.56315460
152Nephrogenic diabetes insipidus (HP:0009806)1.55094197
153Choanal stenosis (HP:0000452)1.54122681
154Enlarged penis (HP:0000040)1.51753544
155Morphological abnormality of the inner ear (HP:0011390)1.51650947

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K94.55077394
2NTRK13.57069812
3NTRK33.55682482
4MARK13.47864326
5STK393.06111034
6KSR22.92168457
7MAP3K42.90640271
8MINK12.57313773
9WNK42.56575086
10TNIK2.55261472
11EPHA42.45301780
12GRK52.34513642
13PAK62.28136082
14MAP3K22.24079711
15LATS22.17727698
16NEK12.09882039
17PNCK2.02702677
18PHKG21.69381297
19PHKG11.69381297
20MAP2K71.68179693
21MAP2K41.66588648
22NTRK21.64950558
23CDK191.64493858
24UHMK11.59792863
25SCYL21.58949779
26PRKD31.55806745
27MAPK151.48397420
28STK381.44954715
29DAPK21.44679091
30RET1.38274957
31BCR1.34973840
32ALK1.25166222
33CDK121.22555922
34CAMKK11.20430225
35WNK11.20089703
36ARAF1.20014826
37CAMK11.10631625
38CDK51.07648409
39MATK1.07481386
40TYRO31.06276070
41PKN11.05803640
42MAPK131.04848551
43KSR11.04764018
44RIPK11.03597353
45SGK2231.01838384
46SGK4941.01838384
47LMTK20.99319715
48CSNK1G20.98206651
49LIMK10.95496785
50WNK30.94903033
51CDK140.93096531
52CDC42BPA0.92770869
53MAP3K120.92281395
54CAMKK20.92148450
55AKT30.91822626
56FER0.89695257
57CAMK2B0.88936629
58TRIB30.88206499
59PRKCG0.86500378
60DAPK10.83301166
61PAK30.81688131
62CDK150.81358581
63HIPK20.80258380
64CDK180.79620691
65MOS0.78706030
66MAP3K10.78672494
67PINK10.77803824
68NEK60.76708895
69DYRK20.76166429
70BMPR1B0.74563641
71CAMK40.74241596
72ICK0.74146216
73SGK20.73213685
74CDK11A0.71035791
75FGFR20.70249486
76MAPK100.67988265
77EPHB20.67764154
78STK110.67336363
79RPS6KA20.67232599
80PLK20.67176679
81OXSR10.66745777
82CDC70.65635630
83SGK30.65427417
84DYRK1B0.65040529
85CSNK1E0.64274850
86CSNK1G30.63673876
87MKNK20.62869017
88PRKCE0.62160200
89MAP2K10.61321902
90DYRK1A0.60674482
91SIK20.56930320
92BRSK10.55688701
93CASK0.53809880
94CDK30.53587806
95PDGFRA0.51815891
96INSRR0.51392410
97ADRBK10.51217329
98PTK20.48829875
99CAMK2A0.46943591
100MAPKAPK50.46834308
101OBSCN0.46397778
102GSK3B0.46294773
103PRKCZ0.46221735
104PRKCH0.46142471
105RPS6KA30.45857406
106CAMK1G0.45323975
107WEE10.45170552
108VRK10.43664278
109CAMK2G0.43102610
110RPS6KB10.41949727
111ROCK20.41763537
112CAMK2D0.41376256
113MARK20.41142131
114PRKG10.40766538
115PRKAA10.40292758
116MAP3K70.39969465
117PRKACA0.39719474
118TAOK10.39278764
119MAPK80.38515446
120PLK30.38437264
121BRAF0.38374852
122TSSK60.38223234
123AURKA0.38012689
124CSNK1G10.37950823
125MARK30.37816495
126PRKACB0.37262965
127ERBB20.35768492
128PRKDC0.35193932
129CSNK1D0.34695882
130CSNK1A1L0.34474579
131SGK10.33480459
132MAPK90.32802061
133CDK20.32227672
134PRKCI0.31465020

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.58300823
2Nicotine addiction_Homo sapiens_hsa050333.04120974
3Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.94446677
4GABAergic synapse_Homo sapiens_hsa047272.57067818
5Phototransduction_Homo sapiens_hsa047442.52073741
6Insulin secretion_Homo sapiens_hsa049112.29134857
7Long-term potentiation_Homo sapiens_hsa047202.27021814
8Circadian entrainment_Homo sapiens_hsa047132.25506383
9Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.24468548
10Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.22453293
11Glutamatergic synapse_Homo sapiens_hsa047242.18849762
12Dopaminergic synapse_Homo sapiens_hsa047282.17483245
13Olfactory transduction_Homo sapiens_hsa047402.13325249
14Taste transduction_Homo sapiens_hsa047422.07663230
15Morphine addiction_Homo sapiens_hsa050321.98987159
16Amphetamine addiction_Homo sapiens_hsa050311.92517774
17Cholinergic synapse_Homo sapiens_hsa047251.87964306
18Long-term depression_Homo sapiens_hsa047301.85665811
19Vitamin B6 metabolism_Homo sapiens_hsa007501.77890600
20Salivary secretion_Homo sapiens_hsa049701.75750252
21Serotonergic synapse_Homo sapiens_hsa047261.71642329
22Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.62672229
23Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.58943192
24Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.56071049
25GnRH signaling pathway_Homo sapiens_hsa049121.51608555
26Gastric acid secretion_Homo sapiens_hsa049711.50606407
27Aldosterone synthesis and secretion_Homo sapiens_hsa049251.48676218
28Oocyte meiosis_Homo sapiens_hsa041141.45190530
29Type II diabetes mellitus_Homo sapiens_hsa049301.43633434
30Gap junction_Homo sapiens_hsa045401.43348274
31Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.39372410
32Estrogen signaling pathway_Homo sapiens_hsa049151.38957838
33Cocaine addiction_Homo sapiens_hsa050301.38769649
34Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.36729112
35Primary bile acid biosynthesis_Homo sapiens_hsa001201.36196934
36Phosphatidylinositol signaling system_Homo sapiens_hsa040701.35978744
37Renin secretion_Homo sapiens_hsa049241.31525209
38Dorso-ventral axis formation_Homo sapiens_hsa043201.27433930
39Histidine metabolism_Homo sapiens_hsa003401.25759646
40Butanoate metabolism_Homo sapiens_hsa006501.24599714
41Propanoate metabolism_Homo sapiens_hsa006401.24088864
42Oxytocin signaling pathway_Homo sapiens_hsa049211.23870911
43Melanogenesis_Homo sapiens_hsa049161.20579693
44Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.19876255
45mTOR signaling pathway_Homo sapiens_hsa041501.19645005
46beta-Alanine metabolism_Homo sapiens_hsa004101.13874170
47Collecting duct acid secretion_Homo sapiens_hsa049661.13718765
48Caffeine metabolism_Homo sapiens_hsa002321.10738266
49Vibrio cholerae infection_Homo sapiens_hsa051101.02408563
50Glioma_Homo sapiens_hsa052141.01529313
51Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.99093094
52Arginine and proline metabolism_Homo sapiens_hsa003300.98679744
53Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.98638896
54Calcium signaling pathway_Homo sapiens_hsa040200.98231427
55Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.98222263
56cAMP signaling pathway_Homo sapiens_hsa040240.97440587
57Thyroid hormone synthesis_Homo sapiens_hsa049180.96194379
58Phospholipase D signaling pathway_Homo sapiens_hsa040720.94343965
59ErbB signaling pathway_Homo sapiens_hsa040120.93687765
60Thyroid cancer_Homo sapiens_hsa052160.86442613
61Thyroid hormone signaling pathway_Homo sapiens_hsa049190.86221964
62cGMP-PKG signaling pathway_Homo sapiens_hsa040220.86138056
63Axon guidance_Homo sapiens_hsa043600.85489767
64Pancreatic secretion_Homo sapiens_hsa049720.85310151
65Endometrial cancer_Homo sapiens_hsa052130.84981116
66Alcoholism_Homo sapiens_hsa050340.84159618
67Central carbon metabolism in cancer_Homo sapiens_hsa052300.82583301
68Cardiac muscle contraction_Homo sapiens_hsa042600.82160596
69Carbohydrate digestion and absorption_Homo sapiens_hsa049730.82125211
70Neurotrophin signaling pathway_Homo sapiens_hsa047220.79880043
71Vascular smooth muscle contraction_Homo sapiens_hsa042700.79778146
72Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.79138743
73Circadian rhythm_Homo sapiens_hsa047100.77724116
74Choline metabolism in cancer_Homo sapiens_hsa052310.77630617
75Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.75556199
76Hedgehog signaling pathway_Homo sapiens_hsa043400.72718375
77Steroid biosynthesis_Homo sapiens_hsa001000.72181232
78Colorectal cancer_Homo sapiens_hsa052100.71717286
79Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.71607072
80Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.69883502
81Insulin signaling pathway_Homo sapiens_hsa049100.69321956
82Maturity onset diabetes of the young_Homo sapiens_hsa049500.68936441
83Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.68935905
84Inositol phosphate metabolism_Homo sapiens_hsa005620.68771945
85Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.67595463
86TGF-beta signaling pathway_Homo sapiens_hsa043500.66557273
87Phenylalanine metabolism_Homo sapiens_hsa003600.65782645
88Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.65495856
89Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.63738556
90Glucagon signaling pathway_Homo sapiens_hsa049220.63271176
91VEGF signaling pathway_Homo sapiens_hsa043700.63056210
92MAPK signaling pathway_Homo sapiens_hsa040100.63028108
93Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.61540043
94Wnt signaling pathway_Homo sapiens_hsa043100.60305072
95mRNA surveillance pathway_Homo sapiens_hsa030150.59342552
96Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.58889730
97Bile secretion_Homo sapiens_hsa049760.58071246
98Retinol metabolism_Homo sapiens_hsa008300.57692187
99Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.57095094
100Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.55847051
101Longevity regulating pathway - mammal_Homo sapiens_hsa042110.55418385
102Hippo signaling pathway_Homo sapiens_hsa043900.54354614
103Renal cell carcinoma_Homo sapiens_hsa052110.52778874
104Folate biosynthesis_Homo sapiens_hsa007900.51986997
105Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.50471902
106Prolactin signaling pathway_Homo sapiens_hsa049170.49881229
107Arginine biosynthesis_Homo sapiens_hsa002200.49507141
108AMPK signaling pathway_Homo sapiens_hsa041520.48829925
109Regulation of autophagy_Homo sapiens_hsa041400.48492655
110Tight junction_Homo sapiens_hsa045300.48235708
111Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.47573037
112Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.47181611
113Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.46619498
114Glycerophospholipid metabolism_Homo sapiens_hsa005640.45988190
115Sphingolipid signaling pathway_Homo sapiens_hsa040710.45777388
116Steroid hormone biosynthesis_Homo sapiens_hsa001400.44823198
117Endocytosis_Homo sapiens_hsa041440.44186252
118Melanoma_Homo sapiens_hsa052180.43232804
119Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.43139226
120Basal cell carcinoma_Homo sapiens_hsa052170.42553206
121Ras signaling pathway_Homo sapiens_hsa040140.41717269
122Non-small cell lung cancer_Homo sapiens_hsa052230.41268649
123Rap1 signaling pathway_Homo sapiens_hsa040150.40471498
124Prion diseases_Homo sapiens_hsa050200.38946280
125Dilated cardiomyopathy_Homo sapiens_hsa054140.34308354
126Ovarian steroidogenesis_Homo sapiens_hsa049130.31727259
127Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.30719659
128Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.30084474
129Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.29509745
130Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.28195979

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