TACC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)7.63628801
2muscle filament sliding (GO:0030049)7.15247039
3actin-myosin filament sliding (GO:0033275)7.15247039
4plasma membrane repair (GO:0001778)6.83733498
5negative regulation of potassium ion transmembrane transporter activity (GO:1901017)6.64105089
6cardiac myofibril assembly (GO:0055003)6.63520645
7regulation of skeletal muscle contraction (GO:0014819)6.51124595
8myofibril assembly (GO:0030239)6.45046899
9positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)6.43561603
10actin-mediated cell contraction (GO:0070252)6.00209509
11negative regulation of potassium ion transmembrane transport (GO:1901380)5.97212257
12sarcoplasmic reticulum calcium ion transport (GO:0070296)5.90531446
13regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)5.80929842
14cardiac muscle contraction (GO:0060048)5.43166350
15regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO5.34314464
16actomyosin structure organization (GO:0031032)5.09268615
17cardiac muscle cell development (GO:0055013)5.02616152
18regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)5.00476340
19striated muscle contraction (GO:0006941)4.98288270
20ventricular cardiac muscle cell action potential (GO:0086005)4.95382094
21carnitine shuttle (GO:0006853)4.88002847
22regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)4.80190960
23bundle of His cell to Purkinje myocyte communication (GO:0086069)4.76667876
24cardiac cell development (GO:0055006)4.75459168
25regulation of cell communication by electrical coupling (GO:0010649)4.70289325
26regulation of relaxation of muscle (GO:1901077)4.70193008
27tricarboxylic acid cycle (GO:0006099)4.70190493
28actin filament-based movement (GO:0030048)4.69503984
29regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.68003987
30regulation of actin filament-based movement (GO:1903115)4.64542239
31skeletal muscle contraction (GO:0003009)4.54055952
32cell communication involved in cardiac conduction (GO:0086065)4.31612835
33adult heart development (GO:0007512)4.29258876
34regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)4.24014247
35response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.22674573
36cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.21431061
37response to muscle activity (GO:0014850)4.20706659
38skeletal muscle adaptation (GO:0043501)4.17941264
39cardiac muscle hypertrophy (GO:0003300)4.17895511
40cardiac muscle tissue morphogenesis (GO:0055008)4.13901511
41fatty acid transmembrane transport (GO:1902001)4.13598428
42regulation of membrane repolarization (GO:0060306)4.09949910
43striated muscle hypertrophy (GO:0014897)4.05999324
44regulation of striated muscle contraction (GO:0006942)3.98528504
45regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.97312979
46regulation of acyl-CoA biosynthetic process (GO:0050812)3.88882829
47muscle tissue morphogenesis (GO:0060415)3.83945283
48desmosome organization (GO:0002934)3.82985503
49skeletal muscle fiber development (GO:0048741)3.81966644
50myotube cell development (GO:0014904)3.80444462
51cell communication by electrical coupling (GO:0010644)3.74600578
52ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.73541438
53positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.68539064
54muscle contraction (GO:0006936)3.65667927
55heart trabecula formation (GO:0060347)3.64873657
56regulation of sarcomere organization (GO:0060297)3.63365036
57carnitine transmembrane transport (GO:1902603)3.61934156
58cardiac muscle cell action potential (GO:0086001)3.59130009
59cardiac muscle cell action potential involved in contraction (GO:0086002)3.57456171
60regulation of coenzyme metabolic process (GO:0051196)3.55914646
61regulation of cofactor metabolic process (GO:0051193)3.55914646
62muscle hypertrophy (GO:0014896)3.46218866
63regulation of the force of heart contraction (GO:0002026)3.45421633
64creatine metabolic process (GO:0006600)3.39423563
65amino-acid betaine transport (GO:0015838)3.38742056
66carnitine transport (GO:0015879)3.38742056
67response to inactivity (GO:0014854)3.37916533
68striated muscle cell development (GO:0055002)3.37376975
69striated muscle adaptation (GO:0014888)3.35083773
70muscle system process (GO:0003012)3.34545037
71negative regulation of potassium ion transport (GO:0043267)3.34008554
72regulation of calcium ion transmembrane transporter activity (GO:1901019)3.31554523
73regulation of calcium ion transmembrane transport (GO:1903169)3.31554523
74striated muscle atrophy (GO:0014891)3.29265191
75regulation of heart rate (GO:0002027)3.28320630
76cardiac conduction (GO:0061337)3.26996222
77regulation of heart rate by cardiac conduction (GO:0086091)3.23066406
78skeletal muscle tissue development (GO:0007519)3.21204178
79relaxation of cardiac muscle (GO:0055119)3.20230329
80positive regulation of cation channel activity (GO:2001259)3.18427493
81muscle atrophy (GO:0014889)3.14899699
82muscle fiber development (GO:0048747)3.13394532
83regulation of cardiac muscle contraction (GO:0055117)3.12261253
84muscle cell cellular homeostasis (GO:0046716)3.12206160
852-oxoglutarate metabolic process (GO:0006103)3.09668433
86NADH metabolic process (GO:0006734)3.08786371
87heart contraction (GO:0060047)3.08071693
88heart process (GO:0003015)3.08071693
89glycogen catabolic process (GO:0005980)3.05243129
90cardiac muscle adaptation (GO:0014887)3.02618219
91cardiac muscle hypertrophy in response to stress (GO:0014898)3.02618219
92muscle hypertrophy in response to stress (GO:0003299)3.02618219
93regulation of cardiac muscle cell contraction (GO:0086004)2.99442265
94regulation of cardioblast differentiation (GO:0051890)2.99305728
95regulation of heart contraction (GO:0008016)2.99159112
96myoblast fusion (GO:0007520)2.98852509
97positive regulation of heart contraction (GO:0045823)2.95243845
98detection of calcium ion (GO:0005513)2.94151384
99membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.93999541
100response to caffeine (GO:0031000)2.93749107
101regulation of sulfur metabolic process (GO:0042762)2.93477203
102muscle cell development (GO:0055001)2.91271499
103negative regulation of protein localization to cell surface (GO:2000009)2.89018819
104positive regulation of heart rate (GO:0010460)2.88166066
105glucan catabolic process (GO:0009251)2.85815020
106regulation of sequestering of triglyceride (GO:0010889)2.84308278
107regulation of ATP catabolic process (GO:1903289)2.83682336
108regulation of ATPase activity (GO:0043462)2.83682336
109positive regulation of sodium ion transport (GO:0010765)2.77606765
110muscle structure development (GO:0061061)2.77180138
111muscle organ development (GO:0007517)2.75024021
112regulation of sodium ion transmembrane transport (GO:1902305)2.74400902
113muscle adaptation (GO:0043500)2.71942830
114myotube differentiation (GO:0014902)2.67021058
115regulation of potassium ion transmembrane transporter activity (GO:1901016)2.66363445
116muscle cell fate commitment (GO:0042693)2.65689350
117positive regulation of ion transmembrane transporter activity (GO:0032414)2.64514191
118regulation of muscle system process (GO:0090257)2.63796107
119negative regulation of calcium ion transmembrane transport (GO:1903170)2.60024981
120negative regulation of calcium ion transmembrane transporter activity (GO:1901020)2.60024981

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.40399342
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.10041552
3EZH2_22144423_ChIP-Seq_EOC_Human3.09734891
4* EP300_21415370_ChIP-Seq_HL-1_Mouse2.92703064
5ESR1_20079471_ChIP-ChIP_T-47D_Human2.73921083
6ZNF263_19887448_ChIP-Seq_K562_Human2.72183679
7TP63_17297297_ChIP-ChIP_HaCaT_Human2.63025244
8* TBX20_22080862_ChIP-Seq_HEART_Mouse2.62578140
9* TBX20_22328084_ChIP-Seq_HEART_Mouse2.62578140
10ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.57014781
11ESR2_21235772_ChIP-Seq_MCF-7_Human2.11196884
12RARG_19884340_ChIP-ChIP_MEFs_Mouse2.10489532
13TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.04350203
14GBX2_23144817_ChIP-Seq_PC3_Human1.99007988
15* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.86126533
16VDR_22108803_ChIP-Seq_LS180_Human1.85165706
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.82680305
18STAT6_21828071_ChIP-Seq_BEAS2B_Human1.80593927
19MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.75593652
20EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.74632824
21GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.73786720
22CDX2_19796622_ChIP-Seq_MESCs_Mouse1.73213650
23RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.71628235
24DROSHA_22980978_ChIP-Seq_HELA_Human1.67685286
25* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.66250904
26ESR1_21235772_ChIP-Seq_MCF-7_Human1.62381702
27CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.59440048
28ZFP281_18757296_ChIP-ChIP_E14_Mouse1.59251556
29EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.58029185
30* NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.56834610
31PIAS1_25552417_ChIP-Seq_VCAP_Human1.53853067
32PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.49313899
33EZH2_18974828_ChIP-Seq_MESCs_Mouse1.46759012
34RNF2_18974828_ChIP-Seq_MESCs_Mouse1.46759012
35CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.46498812
36SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.44001446
37CLOCK_20551151_ChIP-Seq_293T_Human1.43522669
38KDM2B_26808549_Chip-Seq_K562_Human1.42684791
39CBX2_27304074_Chip-Seq_ESCs_Mouse1.38602610
40WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.38433870
41TRIM28_21343339_ChIP-Seq_HEK293_Human1.37965054
42CTCF_27219007_Chip-Seq_Bcells_Human1.36111608
43* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.35733203
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.35663416
45KDM2B_26808549_Chip-Seq_SUP-B15_Human1.33573097
46PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.33155077
47SMAD4_21799915_ChIP-Seq_A2780_Human1.30755312
48ZFP57_27257070_Chip-Seq_ESCs_Mouse1.30500649
49SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.29030454
50EZH2_27294783_Chip-Seq_ESCs_Mouse1.28499436
51ISL1_27105846_Chip-Seq_CPCs_Mouse1.28248545
52ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.27674625
53NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.27123086
54MTF2_20144788_ChIP-Seq_MESCs_Mouse1.26761666
55EZH2_27304074_Chip-Seq_ESCs_Mouse1.26552213
56NR3C1_21868756_ChIP-Seq_MCF10A_Human1.25938293
57AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.24343241
58RUNX1_27514584_Chip-Seq_MCF-7_Human1.23261170
59IGF1R_20145208_ChIP-Seq_DFB_Human1.23226733
60* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.22431477
61* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.20719395
62* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.20054275
63* CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.19176488
64ZNF217_24962896_ChIP-Seq_MCF-7_Human1.19093211
65SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.18227433
66THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.17836896
67ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.17768683
68* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.15593302
69AR_21572438_ChIP-Seq_LNCaP_Human1.14679464
70* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.14223834
71SMAD3_21741376_ChIP-Seq_HESCs_Human1.14064865
72* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.14040289
73ZNF274_21170338_ChIP-Seq_K562_Hela1.13988856
74RACK7_27058665_Chip-Seq_MCF-7_Human1.13950778
75EED_16625203_ChIP-ChIP_MESCs_Mouse1.13928988
76* TP63_22573176_ChIP-Seq_HFKS_Human1.13329657
77RARB_27405468_Chip-Seq_BRAIN_Mouse1.13193390
78* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.11719724
79KDM2B_26808549_Chip-Seq_DND41_Human1.11667718
80AHR_22903824_ChIP-Seq_MCF-7_Human1.10905921
81EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.09580915
82LXR_22292898_ChIP-Seq_THP-1_Human1.09567774
83CREB1_26743006_Chip-Seq_LNCaP_Human1.09446764
84SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.08568233
85JARID2_20075857_ChIP-Seq_MESCs_Mouse1.08387284
86GATA4_21415370_ChIP-Seq_HL-1_Mouse1.07516979
87ATF3_27146783_Chip-Seq_COLON_Human1.07256027
88NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.06422330
89JARID2_20064375_ChIP-Seq_MESCs_Mouse1.05659088
90CTBP2_25329375_ChIP-Seq_LNCAP_Human1.04469566
91SMAD4_21741376_ChIP-Seq_HESCs_Human1.04447157
92UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.03854085
93TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.03843745
94* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.02571515
95KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.02406176
96P300_27058665_Chip-Seq_ZR-75-30cells_Human1.02238925
97FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.02189499
98TP53_20018659_ChIP-ChIP_R1E_Mouse1.02178720
99* TCF4_23295773_ChIP-Seq_U87_Human1.01945102
100RNF2_27304074_Chip-Seq_ESCs_Mouse1.01491394
101ERG_21242973_ChIP-ChIP_JURKAT_Human1.01490763
102AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.01252018
103RXR_22108803_ChIP-Seq_LS180_Human1.01107684
104* SOX2_21211035_ChIP-Seq_LN229_Gbm0.99988631
105ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.99957545
106HIF1A_21447827_ChIP-Seq_MCF-7_Human0.99941224
107SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.99750421
108DNAJC2_21179169_ChIP-ChIP_NT2_Human0.99521790
109SUZ12_27294783_Chip-Seq_ESCs_Mouse0.99186814
110* MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.99171695
111BMI1_23680149_ChIP-Seq_NPCS_Mouse0.98703375
112* STAT3_23295773_ChIP-Seq_U87_Human0.98539536
113ER_23166858_ChIP-Seq_MCF-7_Human0.98121236
114ZFP281_27345836_Chip-Seq_ESCs_Mouse0.97761422
115RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.97323797
116TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96854898
117TAF15_26573619_Chip-Seq_HEK293_Human0.96589024
118FOXM1_26456572_ChIP-Seq_MCF-7_Human0.96546784
119SMAD3_21741376_ChIP-Seq_EPCs_Human0.96037841
120ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.95414543
121* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.94892699
122FOXO3_23340844_ChIP-Seq_DLD1_Human0.94203072
123ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.93018006
124* TOP2B_26459242_ChIP-Seq_MCF-7_Human0.92487426
125CJUN_26792858_Chip-Seq_BT549_Human0.92415068
126AR_25329375_ChIP-Seq_VCAP_Human0.91776211
127TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.91505363
128* FOXA2_19822575_ChIP-Seq_HepG2_Human0.90314853
129SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.89711413
130* AR_19668381_ChIP-Seq_PC3_Human0.89592208
131RING1B_27294783_Chip-Seq_ESCs_Mouse0.89582702
132KLF5_20875108_ChIP-Seq_MESCs_Mouse0.89281811
133TCF4_18268006_ChIP-ChIP_LS174T_Human0.89000720
134* TP53_23651856_ChIP-Seq_MEFs_Mouse0.88889799
135NFIB_24661679_ChIP-Seq_LUNG_Mouse0.88735014
136ARNT_22903824_ChIP-Seq_MCF-7_Human0.88385954
137* CTNNB1_20460455_ChIP-Seq_HCT116_Human0.87245036
138IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.86744670
139CBP_20019798_ChIP-Seq_JUKART_Human0.86744670
140PCGF2_27294783_Chip-Seq_ESCs_Mouse0.86222405
141BCAT_22108803_ChIP-Seq_LS180_Human0.85172585
142REST_21632747_ChIP-Seq_MESCs_Mouse0.85103516
143SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.84600182
144SUZ12_27294783_Chip-Seq_NPCs_Mouse0.84308889
145KDM2B_26808549_Chip-Seq_JURKAT_Human0.83673635
146NRF2_20460467_ChIP-Seq_MEFs_Mouse0.82558909
147NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.82558909

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis6.02029829
2MP0003646_muscle_fatigue5.49489863
3MP0000751_myopathy5.28967862
4MP0004084_abnormal_cardiac_muscle4.41955595
5MP0000749_muscle_degeneration4.07482973
6MP0004215_abnormal_myocardial_fiber3.76070405
7MP0004036_abnormal_muscle_relaxation3.75526678
8MP0004145_abnormal_muscle_electrophysio3.66481501
9MP0005330_cardiomyopathy3.16690314
10MP0004087_abnormal_muscle_fiber3.08476334
11MP0000750_abnormal_muscle_regeneration2.80748651
12MP0002106_abnormal_muscle_physiology2.73037927
13MP0005620_abnormal_muscle_contractility2.71354229
14MP0002269_muscular_atrophy2.58242083
15MP0004130_abnormal_muscle_cell2.56439606
16MP0000747_muscle_weakness2.53050581
17MP0002972_abnormal_cardiac_muscle2.52735815
18MP0000759_abnormal_skeletal_muscle2.36315009
19MP0003137_abnormal_impulse_conducting2.29107794
20MP0005369_muscle_phenotype2.29046839
21MP0004484_altered_response_of2.23550677
22MP0008775_abnormal_heart_ventricle2.19726583
23MP0010630_abnormal_cardiac_muscle2.16282790
24MP0004233_abnormal_muscle_weight2.07062165
25MP0001544_abnormal_cardiovascular_syste2.01096166
26MP0005385_cardiovascular_system_phenoty2.01096166
27MP0006138_congestive_heart_failure1.94758092
28MP0003705_abnormal_hypodermis_morpholog1.68674139
29MP0004085_abnormal_heartbeat1.67234929
30MP0005666_abnormal_adipose_tissue1.62258438
31MP0002234_abnormal_pharynx_morphology1.51625976
32MP0004185_abnormal_adipocyte_glucose1.48288351
33MP0003221_abnormal_cardiomyocyte_apopto1.46484642
34MP0002127_abnormal_cardiovascular_syste1.45767557
35MP0002332_abnormal_exercise_endurance1.38779887
36MP0003828_pulmonary_edema1.35256875
37MP0002108_abnormal_muscle_morphology1.33652505
38MP0005275_abnormal_skin_tensile1.29009591
39MP0005670_abnormal_white_adipose1.28948748
40MP0004510_myositis1.23071094
41MP0005375_adipose_tissue_phenotype1.17101530
42MP0003950_abnormal_plasma_membrane1.16722518
43MP0000733_abnormal_muscle_development1.14689875
44MP0002909_abnormal_adrenal_gland1.14155971
45MP0002822_catalepsy1.12753874
46MP0005451_abnormal_body_composition1.11640376
47MP0006036_abnormal_mitochondrial_physio1.11548364
48MP0005187_abnormal_penis_morphology1.05687425
49MP0000579_abnormal_nail_morphology1.02711820
50MP0001984_abnormal_olfaction1.02658841
51MP0000266_abnormal_heart_morphology1.01193367
52MP0008961_abnormal_basal_metabolism0.99956010
53MP0001661_extended_life_span0.96733879
54MP0009780_abnormal_chondrocyte_physiolo0.96448371
55MP0006276_abnormal_autonomic_nervous0.95349256
56MP0003566_abnormal_cell_adhesion0.95065919
57MP0005623_abnormal_meninges_morphology0.93672592
58MP0002876_abnormal_thyroid_physiology0.86344164
59MP0003567_abnormal_fetal_cardiomyocyte0.86335904
60MP0000013_abnormal_adipose_tissue0.86095832
61MP0003879_abnormal_hair_cell0.84472326
62MP0002796_impaired_skin_barrier0.81770125
63MP0000566_synostosis0.81433336
64MP0000383_abnormal_hair_follicle0.79922648
65MP0003941_abnormal_skin_development0.77505930
66MP0004043_abnormal_pH_regulation0.77354798
67MP0004272_abnormal_basement_membrane0.76754970
68MP0010368_abnormal_lymphatic_system0.76594569
69MP0003283_abnormal_digestive_organ0.76539710
70MP0000003_abnormal_adipose_tissue0.75846937
71MP0003045_fibrosis0.71055549
72MP0002971_abnormal_brown_adipose0.68796137
73MP0005165_increased_susceptibility_to0.67728820
74MP0004270_analgesia0.66040930
75MP0001485_abnormal_pinna_reflex0.65876984
76MP0001299_abnormal_eye_distance/0.65448529
77MP0005266_abnormal_metabolism0.65348889
78MP0000343_altered_response_to0.64862250
79MP0002638_abnormal_pupillary_reflex0.64845950
80MP0004858_abnormal_nervous_system0.64095413
81MP0002734_abnormal_mechanical_nocicepti0.62803722
82MP0005423_abnormal_somatic_nervous0.62771138
83MP0000762_abnormal_tongue_morphology0.62729058
84MP0010234_abnormal_vibrissa_follicle0.61297368
85MP0005083_abnormal_biliary_tract0.60196920
86MP0002128_abnormal_blood_circulation0.59970053
87MP0006035_abnormal_mitochondrial_morpho0.59621388
88MP0003279_aneurysm0.59084772
89MP0000230_abnormal_systemic_arterial0.58622627
90MP0002896_abnormal_bone_mineralization0.57241595
91MP0002653_abnormal_ependyma_morphology0.53287949
92MP0002272_abnormal_nervous_system0.53131461
93MP0004924_abnormal_behavior0.52624522
94MP0005386_behavior/neurological_phenoty0.52624522
95MP0001502_abnormal_circadian_rhythm0.51619598
96MP0008438_abnormal_cutaneous_collagen0.50483386
97MP0002925_abnormal_cardiovascular_devel0.49503183
98MP0010678_abnormal_skin_adnexa0.49366301
99MP0002078_abnormal_glucose_homeostasis0.48954097
100MP0003011_delayed_dark_adaptation0.48853272
101MP0005646_abnormal_pituitary_gland0.46948597
102MP0004859_abnormal_synaptic_plasticity0.46811063
103MP0001440_abnormal_grooming_behavior0.45214310
104MP0004142_abnormal_muscle_tone0.44835911
105MP0002249_abnormal_larynx_morphology0.44782935
106MP0009384_cardiac_valve_regurgitation0.44739309
107MP0001849_ear_inflammation0.44681713
108MP0005409_darkened_coat_color0.43927786
109MP0002877_abnormal_melanocyte_morpholog0.43095796
110MP0005551_abnormal_eye_electrophysiolog0.42177090
111MP0001486_abnormal_startle_reflex0.41940223
112MP0005167_abnormal_blood-brain_barrier0.39948961
113MP0003385_abnormal_body_wall0.39570738
114MP0001784_abnormal_fluid_regulation0.38640723
115MP0008789_abnormal_olfactory_epithelium0.36815242
116MP0000767_abnormal_smooth_muscle0.36715219
117MP0009745_abnormal_behavioral_response0.36683999
118MP0008569_lethality_at_weaning0.36566737
119MP0005076_abnormal_cell_differentiation0.36521448
120MP0002184_abnormal_innervation0.36502083
121MP0004885_abnormal_endolymph0.36125846
122MP0009250_abnormal_appendicular_skeleto0.35490005
123MP0010030_abnormal_orbit_morphology0.33466562
124MP0003119_abnormal_digestive_system0.32328059
125MP0003935_abnormal_craniofacial_develop0.32241842
126MP0000467_abnormal_esophagus_morphology0.31889805
127MP0003948_abnormal_gas_homeostasis0.31247449
128MP0000537_abnormal_urethra_morphology0.31140005
129MP0006072_abnormal_retinal_apoptosis0.30762105
130MP0005503_abnormal_tendon_morphology0.30538588
131MP0005334_abnormal_fat_pad0.30506473
132MP0001879_abnormal_lymphatic_vessel0.30480270
133MP0000534_abnormal_ureter_morphology0.30129544
134MP0003984_embryonic_growth_retardation0.29526201

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)6.72585058
2Exercise-induced myalgia (HP:0003738)6.62901641
3Exercise-induced muscle cramps (HP:0003710)6.15533184
4Calf muscle hypertrophy (HP:0008981)6.14316709
5Muscle fiber splitting (HP:0003555)5.96847983
6Muscle hypertrophy of the lower extremities (HP:0008968)5.92496993
7Ventricular tachycardia (HP:0004756)5.52118367
8Hyporeflexia of lower limbs (HP:0002600)5.40201233
9Abnormality of the calf musculature (HP:0001430)5.05443224
10Muscle fiber inclusion bodies (HP:0100299)4.96599034
11Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)4.85781033
12Right ventricular cardiomyopathy (HP:0011663)4.73798519
13Type 1 muscle fiber predominance (HP:0003803)4.73089232
14Increased connective tissue (HP:0009025)4.72430089
15Myoglobinuria (HP:0002913)4.68038162
16Difficulty running (HP:0009046)4.54819958
17Atrial fibrillation (HP:0005110)4.35721186
18EMG: myopathic abnormalities (HP:0003458)4.35676923
19Subaortic stenosis (HP:0001682)4.22733575
20Abnormality of the left ventricular outflow tract (HP:0011103)4.22733575
21Nemaline bodies (HP:0003798)4.12490219
22Primary atrial arrhythmia (HP:0001692)4.10562604
23Supraventricular tachycardia (HP:0004755)3.91938961
24Lipoatrophy (HP:0100578)3.89101678
25Bundle branch block (HP:0011710)3.88527435
26Supraventricular arrhythmia (HP:0005115)3.86276807
27Myotonia (HP:0002486)3.76711396
28Syncope (HP:0001279)3.64160638
29Distal arthrogryposis (HP:0005684)3.50595005
30Difficulty climbing stairs (HP:0003551)3.50490930
31Rhabdomyolysis (HP:0003201)3.47531587
32Asymmetric septal hypertrophy (HP:0001670)3.39505134
33Prolonged QT interval (HP:0001657)3.29191724
34Dilated cardiomyopathy (HP:0001644)3.28151209
35Ventricular arrhythmia (HP:0004308)3.25061831
36Increased variability in muscle fiber diameter (HP:0003557)3.22158709
37Myopathic facies (HP:0002058)3.15384146
38Abnormality of skeletal muscle fiber size (HP:0012084)3.09343644
39Muscle stiffness (HP:0003552)3.05475906
40Palpitations (HP:0001962)3.04642315
41Ventricular fibrillation (HP:0001663)3.04600136
42Round ear (HP:0100830)3.04404243
43Heart block (HP:0012722)2.98357529
44Hypoplastic ischia (HP:0003175)2.93857720
45Abnormal atrioventricular conduction (HP:0005150)2.88637341
46Neck muscle weakness (HP:0000467)2.86188877
47Distal lower limb muscle weakness (HP:0009053)2.82528375
48Mildly elevated creatine phosphokinase (HP:0008180)2.80337363
49Fetal akinesia sequence (HP:0001989)2.72787001
50Malignant hyperthermia (HP:0002047)2.69550751
51Atrioventricular block (HP:0001678)2.68119008
52Rimmed vacuoles (HP:0003805)2.64117475
53Areflexia of lower limbs (HP:0002522)2.60809667
54Ulnar deviation of the wrist (HP:0003049)2.59162331
55Abnormality of the ischium (HP:0003174)2.57594009
56Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.56177410
57Limb-girdle muscle atrophy (HP:0003797)2.51168469
58EMG: neuropathic changes (HP:0003445)2.49491345
59Abnormal EKG (HP:0003115)2.37665941
60Scapular winging (HP:0003691)2.31874557
61Bulbar palsy (HP:0001283)2.29394472
62Proximal amyotrophy (HP:0007126)2.28191527
63Ketoacidosis (HP:0001993)2.26547530
64Distal lower limb amyotrophy (HP:0008944)2.25756411
65Muscular dystrophy (HP:0003560)2.23811065
66Frequent falls (HP:0002359)2.17256092
67Hip contracture (HP:0003273)2.16213881
68Palmoplantar keratoderma (HP:0000982)2.14460999
69Testicular atrophy (HP:0000029)2.10849139
70Left ventricular hypertrophy (HP:0001712)2.10585983
71Spinal rigidity (HP:0003306)2.09713598
72Popliteal pterygium (HP:0009756)2.09303467
73Absent phalangeal crease (HP:0006109)2.04115728
74Generalized muscle weakness (HP:0003324)1.97633567
75Abnormality of the foot musculature (HP:0001436)1.96267857
76Limb-girdle muscle weakness (HP:0003325)1.95764172
77Dysmetric saccades (HP:0000641)1.95595795
78Waddling gait (HP:0002515)1.94223025
79Gowers sign (HP:0003391)1.91867435
80Foot dorsiflexor weakness (HP:0009027)1.91793157
81Weak cry (HP:0001612)1.91248748
82Facial diplegia (HP:0001349)1.89149960
83Hamartoma of the eye (HP:0010568)1.87787451
84Calcaneovalgus deformity (HP:0001848)1.86392103
85Lower limb amyotrophy (HP:0007210)1.81586340
86Nonprogressive disorder (HP:0003680)1.81289288
87Broad metatarsal (HP:0001783)1.81049773
88Hyperglycemia (HP:0003074)1.78078963
89Hyperkalemia (HP:0002153)1.77661425
90Conjunctival hamartoma (HP:0100780)1.76611606
91Abnormal ciliary motility (HP:0012262)1.76545144
92Aplasia of the musculature (HP:0100854)1.74406457
93Abnormality of the shoulder girdle musculature (HP:0001435)1.71592609
94Steppage gait (HP:0003376)1.71491357
95Absent/shortened dynein arms (HP:0200106)1.70768582
96Dynein arm defect of respiratory motile cilia (HP:0012255)1.70768582
97Deformed tarsal bones (HP:0008119)1.67799994
98Abnormality of potassium homeostasis (HP:0011042)1.67246587
99Insulin-resistant diabetes mellitus (HP:0000831)1.67203744
100Hypoglycemic coma (HP:0001325)1.66188266
101Abnormal respiratory epithelium morphology (HP:0012253)1.65744698
102Abnormal respiratory motile cilium morphology (HP:0005938)1.65744698
103Abnormality of the neuromuscular junction (HP:0003398)1.64850521
104Fatigable weakness (HP:0003473)1.64850521
105Large for gestational age (HP:0001520)1.64245140
106Abnormal finger flexion creases (HP:0006143)1.62729318
107Abnormal respiratory motile cilium physiology (HP:0012261)1.61652057
108Abnormality of the pubic bones (HP:0003172)1.61129175
109Limited hip movement (HP:0008800)1.60182793
110Hyperinsulinemic hypoglycemia (HP:0000825)1.59993672
111Lymphangioma (HP:0100764)1.56537991
112Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.56262041
113Shoulder girdle muscle weakness (HP:0003547)1.55932465
114Sudden cardiac death (HP:0001645)1.55252712
115Centrally nucleated skeletal muscle fibers (HP:0003687)1.54797349
116Oligomenorrhea (HP:0000876)1.54008461
117Central scotoma (HP:0000603)1.52859203
118Rapidly progressive (HP:0003678)1.51964416
119Respiratory insufficiency due to muscle weakness (HP:0002747)1.46805365

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN5.48573896
2OBSCN5.32252717
3PHKG14.23278551
4PHKG24.23278551
5TRIB32.84828419
6LMTK22.83247386
7DMPK2.69503498
8PDK32.43864966
9PDK42.43864966
10NEK12.37187712
11PKN22.12271651
12PINK11.96065591
13LATS11.94607218
14MYLK1.83098243
15PIK3CA1.77786477
16FRK1.74777427
17MUSK1.61254091
18ICK1.59553202
19LATS21.50516301
20NME11.49628239
21RIPK11.44389146
22BCKDK1.43519717
23MAP3K71.41410190
24PDK21.36612012
25PDGFRA1.35232258
26TIE11.29720506
27PAK31.28066561
28MAPK151.25781573
29MAPKAPK31.19330678
30STK241.13430548
31STK38L1.12629129
32STK381.07923485
33EPHA31.01718098
34PIK3CG0.99872287
35PRKAA10.98454669
36INSRR0.97928493
37PRKD10.97695303
38FER0.97041897
39MAP3K30.96833580
40AKT30.95040006
41CDC42BPA0.94190032
42EPHA20.93984384
43PRKD30.93238157
44MAPK120.90834707
45MAP2K40.90580618
46MAP2K30.89214015
47ROCK10.88014139
48WNK40.87601806
49CAMK2D0.85984948
50DDR20.84679223
51LIMK10.82804183
52SGK20.82734961
53TAOK10.82644742
54SIK10.79855814
55SGK2230.77881037
56SGK4940.77881037
57PRKAA20.77102838
58PTK60.76033580
59STK390.74930477
60MAPK130.74929074
61ILK0.73105254
62EPHB20.72126774
63MST1R0.71650077
64PAK60.69340101
65MAP3K50.66775485
66CASK0.65718323
67MTOR0.60673155
68MET0.59993769
69BMPR1B0.59700300
70MAP3K40.59470912
71AKT20.58927127
72WNK10.57322761
73GRK10.56695828
74ZAK0.56682763
75KSR20.56315449
76OXSR10.54736111
77GRK70.54269402
78CAMK40.54020562
79ERBB30.53431739
80DAPK20.53061286
81MARK10.51645629
82CAMK2B0.50426002
83MAP3K90.50055508
84MAP3K10.48499958
85CAMK1G0.48437250
86RET0.46871001
87MAPK40.46534384
88TRPM70.46485977
89CAMK2A0.46463656
90RPS6KA20.45480358
91TYRO30.45070481
92MAPK70.44506200
93ROCK20.43896143
94DYRK1B0.43593429
95CAMK1D0.41922048
96SGK30.40916996
97SGK10.39456386
98MAP2K60.39078136
99EPHB10.38330846
100PRKACB0.37956349
101EEF2K0.37574035
102NLK0.37209744
103PRKCH0.36709958
104PKN10.35450508
105PTK20.35239436
106PRKACA0.33996088
107MAP2K10.33906092
108CAMK2G0.33603568
109RPS6KA30.33006733
110PRKACG0.32956885
111CCNB10.32752619
112NEK90.30975984
113MAP3K60.30968891
114STK110.30723157
115NTRK30.30546217
116KSR10.30440080
117PTK2B0.30439022
118RPS6KA60.30145481
119ERN10.30110616
120FGFR10.29264477
121WNK30.29065451
122CAMK10.28673923
123MAPK110.28063547
124RPS6KB10.27977879
125ADRBK10.27667822
126RPS6KA10.26949666
127PDGFRB0.26811209
128PRKD20.26752462
129MARK20.26556763
130CDK120.25905509
131PRKCE0.24608256
132RPS6KB20.24587864
133PDPK10.23539954
134PRKG10.21795510

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000204.56643620
22-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.57098840
3Dilated cardiomyopathy_Homo sapiens_hsa054143.55017142
4Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.52018334
5Cardiac muscle contraction_Homo sapiens_hsa042603.46363483
6Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.92983029
7Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.84573847
8Propanoate metabolism_Homo sapiens_hsa006402.30596283
9Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.99107044
10Fatty acid degradation_Homo sapiens_hsa000711.97222886
11Carbon metabolism_Homo sapiens_hsa012001.78804536
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.59982639
13Fatty acid metabolism_Homo sapiens_hsa012121.55017138
14Parkinsons disease_Homo sapiens_hsa050121.43527003
15Glucagon signaling pathway_Homo sapiens_hsa049221.41019207
16Viral myocarditis_Homo sapiens_hsa054161.40764982
17Histidine metabolism_Homo sapiens_hsa003401.40302053
18Insulin resistance_Homo sapiens_hsa049311.36896710
19Insulin signaling pathway_Homo sapiens_hsa049101.34348322
20Linoleic acid metabolism_Homo sapiens_hsa005911.30429625
21Oxidative phosphorylation_Homo sapiens_hsa001901.29024769
22Alzheimers disease_Homo sapiens_hsa050101.28453590
23cGMP-PKG signaling pathway_Homo sapiens_hsa040221.25342819
24Oxytocin signaling pathway_Homo sapiens_hsa049211.22365231
25Pyruvate metabolism_Homo sapiens_hsa006201.21013701
26alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.18570373
27Tight junction_Homo sapiens_hsa045301.18241444
28Nitrogen metabolism_Homo sapiens_hsa009101.14006187
29Focal adhesion_Homo sapiens_hsa045101.13350571
30Starch and sucrose metabolism_Homo sapiens_hsa005001.10856961
31Butanoate metabolism_Homo sapiens_hsa006501.10208857
32Calcium signaling pathway_Homo sapiens_hsa040201.09432360
33Insulin secretion_Homo sapiens_hsa049111.07331997
34Gastric acid secretion_Homo sapiens_hsa049711.06202898
35AMPK signaling pathway_Homo sapiens_hsa041521.05713021
36Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.04468853
37Adipocytokine signaling pathway_Homo sapiens_hsa049201.03510979
38ABC transporters_Homo sapiens_hsa020101.02950477
39Type II diabetes mellitus_Homo sapiens_hsa049301.02665488
40Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.00973410
41Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.99479152
42Adherens junction_Homo sapiens_hsa045200.98590682
43Circadian rhythm_Homo sapiens_hsa047100.98455896
44Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.97459747
45GnRH signaling pathway_Homo sapiens_hsa049120.96416611
46Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.93687459
47Phototransduction_Homo sapiens_hsa047440.93637911
48ECM-receptor interaction_Homo sapiens_hsa045120.92510656
49Lysine degradation_Homo sapiens_hsa003100.91210767
50Vascular smooth muscle contraction_Homo sapiens_hsa042700.88738155
51Dorso-ventral axis formation_Homo sapiens_hsa043200.86747547
52Thyroid hormone signaling pathway_Homo sapiens_hsa049190.86132962
53Biosynthesis of amino acids_Homo sapiens_hsa012300.85161235
54PPAR signaling pathway_Homo sapiens_hsa033200.84769400
55Renin secretion_Homo sapiens_hsa049240.84433522
56Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.83451754
57Huntingtons disease_Homo sapiens_hsa050160.83397898
58Arginine biosynthesis_Homo sapiens_hsa002200.82920014
59Longevity regulating pathway - mammal_Homo sapiens_hsa042110.82538083
60Tyrosine metabolism_Homo sapiens_hsa003500.82462351
61Circadian entrainment_Homo sapiens_hsa047130.79643133
62Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.77957167
63mTOR signaling pathway_Homo sapiens_hsa041500.76386072
64Aldosterone synthesis and secretion_Homo sapiens_hsa049250.75733764
65Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.74721714
66Central carbon metabolism in cancer_Homo sapiens_hsa052300.73861792
67Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.72966006
68Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.69829390
69Gap junction_Homo sapiens_hsa045400.68668627
70cAMP signaling pathway_Homo sapiens_hsa040240.68377967
71Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.67349332
72Glutamatergic synapse_Homo sapiens_hsa047240.65513212
73Basal cell carcinoma_Homo sapiens_hsa052170.65064189
74Serotonergic synapse_Homo sapiens_hsa047260.64515341
75Long-term potentiation_Homo sapiens_hsa047200.64412948
76Proteoglycans in cancer_Homo sapiens_hsa052050.64376521
77Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.63108781
78Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.62770217
79Long-term depression_Homo sapiens_hsa047300.61500139
80Salivary secretion_Homo sapiens_hsa049700.61299716
81Hippo signaling pathway_Homo sapiens_hsa043900.60368934
82HIF-1 signaling pathway_Homo sapiens_hsa040660.60186331
83Fatty acid biosynthesis_Homo sapiens_hsa000610.60116787
84Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.60084429
85Tryptophan metabolism_Homo sapiens_hsa003800.59602216
86Steroid hormone biosynthesis_Homo sapiens_hsa001400.58477752
87Nicotine addiction_Homo sapiens_hsa050330.58114317
88Estrogen signaling pathway_Homo sapiens_hsa049150.58022341
89Endometrial cancer_Homo sapiens_hsa052130.57484264
90VEGF signaling pathway_Homo sapiens_hsa043700.57252779
91Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.57064016
92Chemical carcinogenesis_Homo sapiens_hsa052040.56732838
93GABAergic synapse_Homo sapiens_hsa047270.55909322
94Renal cell carcinoma_Homo sapiens_hsa052110.55227196
95Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.54696720
96Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.54340942
97Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.54177104
98Cholinergic synapse_Homo sapiens_hsa047250.54149011
99Olfactory transduction_Homo sapiens_hsa047400.52815601
100Arginine and proline metabolism_Homo sapiens_hsa003300.52544722
101Melanogenesis_Homo sapiens_hsa049160.52476780
102Amoebiasis_Homo sapiens_hsa051460.52447846
103Galactose metabolism_Homo sapiens_hsa000520.51816072
104Protein digestion and absorption_Homo sapiens_hsa049740.51768027
105Peroxisome_Homo sapiens_hsa041460.51579452
106Bile secretion_Homo sapiens_hsa049760.51082387
107Morphine addiction_Homo sapiens_hsa050320.50363759
108Pancreatic secretion_Homo sapiens_hsa049720.49109148
109Regulation of actin cytoskeleton_Homo sapiens_hsa048100.48996258
110Fructose and mannose metabolism_Homo sapiens_hsa000510.48408070
111Hedgehog signaling pathway_Homo sapiens_hsa043400.46515457
112Phenylalanine metabolism_Homo sapiens_hsa003600.46447748
113Taste transduction_Homo sapiens_hsa047420.45077226
114Glioma_Homo sapiens_hsa052140.44945667
115Retinol metabolism_Homo sapiens_hsa008300.44803614
116Ether lipid metabolism_Homo sapiens_hsa005650.43900088
117beta-Alanine metabolism_Homo sapiens_hsa004100.43071619
118Ovarian steroidogenesis_Homo sapiens_hsa049130.39785155
119FoxO signaling pathway_Homo sapiens_hsa040680.38892074
120Amphetamine addiction_Homo sapiens_hsa050310.37822893
121MAPK signaling pathway_Homo sapiens_hsa040100.37769540
122Fatty acid elongation_Homo sapiens_hsa000620.36727083
123Axon guidance_Homo sapiens_hsa043600.35260530
124Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.35199172
125Dopaminergic synapse_Homo sapiens_hsa047280.33772508
126Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.33398949

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