TACSTD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1keratinization (GO:0031424)9.08255970
2hemidesmosome assembly (GO:0031581)8.39686365
3keratinocyte differentiation (GO:0030216)7.26035291
4multicellular organismal water homeostasis (GO:0050891)7.21881188
5interferon-gamma secretion (GO:0072643)7.06453195
6keratinocyte proliferation (GO:0043616)6.80121639
7hair cycle (GO:0042633)6.74778354
8molting cycle (GO:0042303)6.74778354
9sphingoid metabolic process (GO:0046519)6.42928612
10bundle of His cell to Purkinje myocyte communication (GO:0086069)6.35425134
11water homeostasis (GO:0030104)6.00684157
12epidermal cell differentiation (GO:0009913)5.79677200
13viral transcription (GO:0019083)5.35662433
14peptide cross-linking (GO:0018149)5.30028751
15sphingosine metabolic process (GO:0006670)5.27144892
16intermediate filament organization (GO:0045109)5.16762464
17diterpenoid biosynthetic process (GO:0016102)5.16427144
18epidermis development (GO:0008544)5.13283308
19translational termination (GO:0006415)5.06717333
20detection of bacterium (GO:0016045)4.99998238
21regulation of cell proliferation involved in kidney development (GO:1901722)4.87719815
22regulation of chemokine secretion (GO:0090196)4.82459273
23ribosomal small subunit biogenesis (GO:0042274)4.81833104
24keratinocyte development (GO:0003334)4.73641070
25diol metabolic process (GO:0034311)4.70330221
26epithelial cell differentiation involved in prostate gland development (GO:0060742)4.68202455
27axonemal dynein complex assembly (GO:0070286)4.46724903
28regulation of phospholipase A2 activity (GO:0032429)4.40510092
29glucosamine-containing compound catabolic process (GO:1901072)4.36368383
30dichotomous subdivision of an epithelial terminal unit (GO:0060600)4.33989091
31positive regulation of interleukin-8 secretion (GO:2000484)4.33656779
32detection of other organism (GO:0098543)4.29327339
33positive regulation of epidermal cell differentiation (GO:0045606)4.27492157
34ribosomal small subunit assembly (GO:0000028)4.21338176
35skin morphogenesis (GO:0043589)4.20159522
36SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.06995239
37negative regulation of cell fate specification (GO:0009996)4.03960799
38regulation of keratinocyte differentiation (GO:0045616)4.02814556
39protein targeting to ER (GO:0045047)3.99901582
40translational elongation (GO:0006414)3.99769813
41cotranslational protein targeting to membrane (GO:0006613)3.97566381
42viral life cycle (GO:0019058)3.95871068
43regulation of keratinocyte proliferation (GO:0010837)3.95619750
44regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.90627139
45polarized epithelial cell differentiation (GO:0030859)3.85841874
46establishment of protein localization to endoplasmic reticulum (GO:0072599)3.84917609
47positive regulation of keratinocyte differentiation (GO:0045618)3.78079072
48cellular protein complex disassembly (GO:0043624)3.77442552
49phospholipid scrambling (GO:0017121)3.74679213
50ectoderm development (GO:0007398)3.74303504
51protein localization to endoplasmic reticulum (GO:0070972)3.71806345
52regulation of interleukin-8 secretion (GO:2000482)3.66932201
53hypotonic response (GO:0006971)3.65217597
54nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.65110099
55maturation of SSU-rRNA (GO:0030490)3.64169952
56terpenoid biosynthetic process (GO:0016114)3.62995456
57gap junction assembly (GO:0016264)3.58092491
58surfactant homeostasis (GO:0043129)3.56946286
59positive regulation of chemokine secretion (GO:0090197)3.55752392
60regulation of transforming growth factor beta2 production (GO:0032909)3.55209500
61cyclooxygenase pathway (GO:0019371)3.53910741
62chemical homeostasis within a tissue (GO:0048875)3.51249831
63atrioventricular valve morphogenesis (GO:0003181)3.50169141
64regulation of hypersensitivity (GO:0002883)3.48259546
65negative regulation of keratinocyte proliferation (GO:0010839)3.42323712
66negative regulation of interleukin-2 production (GO:0032703)3.41685412
67positive regulation of Cdc42 GTPase activity (GO:0043089)3.41242450
68COPI coating of Golgi vesicle (GO:0048205)3.41033485
69Golgi transport vesicle coating (GO:0048200)3.41033485
70lateral sprouting from an epithelium (GO:0060601)3.38911272
71long-chain fatty acid biosynthetic process (GO:0042759)3.38584275
72negative regulation of interferon-gamma production (GO:0032689)3.37832313
73apical protein localization (GO:0045176)3.35152854
74ear development (GO:0043583)3.33182722
75negative regulation of cell fate commitment (GO:0010454)3.32214256
76regulation of epidermis development (GO:0045682)3.32153037
77eyelid development in camera-type eye (GO:0061029)3.26264827
78regulation of transforming growth factor beta1 production (GO:0032908)3.24296822
79establishment of apical/basal cell polarity (GO:0035089)3.24153441
80intermediate filament cytoskeleton organization (GO:0045104)3.23810826
81gland morphogenesis (GO:0022612)3.22875110
82cytoskeletal anchoring at plasma membrane (GO:0007016)3.22408864
83cardiac right ventricle morphogenesis (GO:0003215)3.21814360
84motile cilium assembly (GO:0044458)3.19591740
85face development (GO:0060324)3.17819754
86primary alcohol catabolic process (GO:0034310)3.16640449
87asymmetric protein localization (GO:0008105)3.16415879
88tight junction assembly (GO:0070830)3.15228351
89protein localization to endosome (GO:0036010)3.15125234
90protein complex disassembly (GO:0043241)3.14248439
91regulation of epidermal cell differentiation (GO:0045604)3.13045511
92intermediate filament-based process (GO:0045103)3.12756066
93translational initiation (GO:0006413)3.11232374
94negative regulation of inflammatory response to antigenic stimulus (GO:0002862)3.10286073
95negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.05271837
96phosphatidylinositol acyl-chain remodeling (GO:0036149)3.02771317
97morphogenesis of embryonic epithelium (GO:0016331)3.02581648
98regulation of cardioblast differentiation (GO:0051890)3.00806177
99intestinal epithelial cell development (GO:0060576)2.98864293
100cilium or flagellum-dependent cell motility (GO:0001539)2.98432683
101regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.98379846
102regulation of natural killer cell differentiation (GO:0032823)2.97264501
103cell-cell junction assembly (GO:0007043)2.97180959
104prostanoid biosynthetic process (GO:0046457)2.95849834
105prostaglandin biosynthetic process (GO:0001516)2.95849834
106lung epithelium development (GO:0060428)2.94365284
107regulation of glomerular filtration (GO:0003093)2.92898988
108lipoxygenase pathway (GO:0019372)2.92293259
109phosphatidylserine acyl-chain remodeling (GO:0036150)2.91237235
110establishment of planar polarity (GO:0001736)2.89717664
111establishment of tissue polarity (GO:0007164)2.89717664
112semaphorin-plexin signaling pathway (GO:0071526)2.88947560
113activation of Rac GTPase activity (GO:0032863)2.88070627
114lung lobe morphogenesis (GO:0060463)2.87911698
115cell adhesion mediated by integrin (GO:0033627)2.87271355
116regulation of interleukin-13 production (GO:0032656)2.85804160
117fatty acid elongation (GO:0030497)2.85292667
118regulation of endothelial cell chemotaxis (GO:2001026)2.84773993
119macromolecular complex disassembly (GO:0032984)2.84176066
120protein targeting to membrane (GO:0006612)2.84094471
121one-carbon compound transport (GO:0019755)2.82917076
122ventricular cardiac muscle cell action potential (GO:0086005)2.82061078
123G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.82020011
124branching involved in mammary gland duct morphogenesis (GO:0060444)2.80640362
125Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.79592031
126ribosomal large subunit biogenesis (GO:0042273)2.78813580
127mammary gland epithelial cell proliferation (GO:0033598)2.78291494
128calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.77651429
129positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.75982278
130amyloid precursor protein metabolic process (GO:0042982)2.75549784
131negative regulation of T cell mediated immunity (GO:0002710)2.74928942
132positive regulation of vesicle fusion (GO:0031340)2.74471488
133cell-substrate junction assembly (GO:0007044)2.73949626
134negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.72821887
135endosome organization (GO:0007032)2.72704658
136regulation of transforming growth factor beta production (GO:0071634)2.72617013
137epithelial cell-cell adhesion (GO:0090136)2.72586337
138regulation of hair follicle development (GO:0051797)2.72368404
139cell junction organization (GO:0034330)2.72151154
140positive regulation of glomerulus development (GO:0090193)2.72066945
141negative regulation of chondrocyte differentiation (GO:0032331)2.71966587
142iron ion import (GO:0097286)2.71961985
143regulation of establishment of planar polarity (GO:0090175)2.71764315
144cell differentiation involved in embryonic placenta development (GO:0060706)2.70753978
145regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.69948270
146negative regulation of acute inflammatory response (GO:0002674)2.69719445
147cell junction assembly (GO:0034329)2.68754949
148planar cell polarity pathway involved in neural tube closure (GO:0090179)2.68417967
149retinoic acid metabolic process (GO:0042573)2.67335412
150positive regulation of epidermis development (GO:0045684)2.66681110
151wound healing, spreading of epidermal cells (GO:0035313)2.64381447
152phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.64013671
153epithelium development (GO:0060429)2.62923103
154positive regulation of interleukin-4 production (GO:0032753)2.62646339
155pyrimidine-containing compound transmembrane transport (GO:0072531)2.62467407
156cilium movement (GO:0003341)2.62060287
157cell-substrate adherens junction assembly (GO:0007045)2.61830353
158focal adhesion assembly (GO:0048041)2.61830353
159mammary gland epithelial cell differentiation (GO:0060644)2.56204372
160desmosome organization (GO:0002934)14.9242326
161establishment of skin barrier (GO:0061436)10.7653936
162regulation of water loss via skin (GO:0033561)10.2417286

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse7.44530383
2P63_26484246_Chip-Seq_KERATINOCYTES_Human2.99919861
3SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.93330862
4SOX9_24532713_ChIP-Seq_HFSC_Mouse2.84906764
5ESR1_21235772_ChIP-Seq_MCF-7_Human2.74605230
6STAT6_21828071_ChIP-Seq_BEAS2B_Human2.56699847
7TRIM28_21343339_ChIP-Seq_HEK293_Human2.43394402
8ZNF263_19887448_ChIP-Seq_K562_Human2.41468994
9* SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.34155846
10* SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.34155846
11ESR2_21235772_ChIP-Seq_MCF-7_Human2.22673878
12TP63_17297297_ChIP-ChIP_HaCaT_Human16.3284450
13FOXO3_23340844_ChIP-Seq_DLD1_Human1.96749927
14CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.88786106
15PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.64886788
16* SOX2_20726797_ChIP-Seq_SW620_Human1.64839684
17ZNF217_24962896_ChIP-Seq_MCF-7_Human1.55396431
18RARG_19884340_ChIP-ChIP_MEFs_Mouse1.51807041
19STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.51116100
20RUNX1_27514584_Chip-Seq_MCF-7_Human1.48357068
21CDX2_20551321_ChIP-Seq_CACO-2_Human1.48045894
22* TCF4_18268006_ChIP-ChIP_LS174T_Human1.36165768
23HIF1A_21447827_ChIP-Seq_MCF-7_Human1.34619148
24BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.33888827
25CJUN_26792858_Chip-Seq_BT549_Human1.33237446
26GATA4_25053715_ChIP-Seq_YYC3_Human1.32698064
27* TP63_23658742_ChIP-Seq_EP156T_Human1.32655547
28* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.31414798
29KLF5_25053715_ChIP-Seq_YYC3_Human1.30165067
30* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.29428229
31GATA1_22025678_ChIP-Seq_K562_Human1.27088421
32CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.26072244
33P300_27058665_Chip-Seq_ZR-75-30cells_Human1.25224125
34ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.21411096
35ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.20314124
36ATF3_27146783_Chip-Seq_COLON_Human1.20024781
37RACK7_27058665_Chip-Seq_MCF-7_Human1.19927894
38ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.18382857
39TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.15099802
40PPAR_26484153_Chip-Seq_NCI-H1993_Human1.12788063
41* TP63_22573176_ChIP-Seq_HFKS_Human1.12023284
42TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.10590780
43* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.10230662
44* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.09960451
45TP53_18474530_ChIP-ChIP_U2OS_Human1.07323538
46SMC4_20622854_ChIP-Seq_HELA_Human1.06093213
47CREB1_26743006_Chip-Seq_LNCaP_Human1.05095405
48FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.04944486
49SOX2_27498859_Chip-Seq_STOMACH_Mouse1.04037816
50GATA6_25053715_ChIP-Seq_YYC3_Human1.04000366
51RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.03982364
52* GATA3_24758297_ChIP-Seq_MCF-7_Human1.02111814
53CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.02095388
54TP53_20018659_ChIP-ChIP_R1E_Mouse1.00627631
55FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.00269391
56* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.99300597
57SRY_22984422_ChIP-ChIP_TESTIS_Rat0.99200606
58* EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.98531111
59RXR_22108803_ChIP-Seq_LS180_Human0.97807548
60ELF5_23300383_ChIP-Seq_T47D_Human0.97668512
61AR_21909140_ChIP-Seq_LNCAP_Human0.97583845
62* UBF1/2_26484160_Chip-Seq_HMECs_Human0.97050346
63PPARA_22158963_ChIP-Seq_LIVER_Mouse0.97045244
64AHR_22903824_ChIP-Seq_MCF-7_Human0.95774086
65KDM2B_26808549_Chip-Seq_SUP-B15_Human0.95316103
66RXR_22158963_ChIP-Seq_LIVER_Mouse0.94090150
67* CHD1_26751641_Chip-Seq_LNCaP_Human0.93552030
68NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.93266678
69ESR1_20079471_ChIP-ChIP_T-47D_Human0.92710663
70KDM2B_26808549_Chip-Seq_K562_Human0.92434312
71ESR1_15608294_ChIP-ChIP_MCF-7_Human0.92311299
72* ERG_21242973_ChIP-ChIP_JURKAT_Human0.91749335
73* GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.91687777
74FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.91622271
75NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.90156838
76TBX20_22080862_ChIP-Seq_HEART_Mouse0.90123270
77TBX20_22328084_ChIP-Seq_HEART_Mouse0.90123270
78PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.89722335
79KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.88735515
80NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.87454671
81EGR1_19032775_ChIP-ChIP_M12_Human0.84685748
82KLF4_18555785_ChIP-Seq_MESCs_Mouse0.83538861
83STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.81514476
84TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.81115643
85AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.81003774
86JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.80380730
87* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.80229743
88GATA2_21666600_ChIP-Seq_HMVEC_Human0.79079752
89ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.78854258
90* CEBPB_22108803_ChIP-Seq_LS180_Human0.77430482
91KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.76760439
92WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.76335000
93LXR_22292898_ChIP-Seq_THP-1_Human0.75240571
94FOXM1_26456572_ChIP-Seq_MCF-7_Human0.75177032
95THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.74689322
96JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.74435871
97TET1_21490601_ChIP-Seq_MESCs_Mouse0.74125863
98* SA1_27219007_Chip-Seq_ERYTHROID_Human0.73999640
99* GATA6_21074721_ChIP-Seq_CACO-2_Human0.73744719
100TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.73432224
101TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.69621009
102FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.68771132
103AR_21572438_ChIP-Seq_LNCaP_Human0.68521853
104TP53_22127205_ChIP-Seq_IMR90_Human0.68499098
105ARNT_22903824_ChIP-Seq_MCF-7_Human0.67013668
106STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.66092985
107CLOCK_20551151_ChIP-Seq_293T_Human0.66023121
108TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.64090844
109ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.63787182
110SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.63532149
111SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.62935916
112CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.62353415
113HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.60621414
114BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.59644581
115BCAT_22108803_ChIP-Seq_LS180_Human0.58442474
116* P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.57483386
117TCF4_22108803_ChIP-Seq_LS180_Human0.55734247
118ELK3_25401928_ChIP-Seq_HUVEC_Human0.55517719
119* CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.54815459
120VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.54116284
121SMAD3_21741376_ChIP-Seq_HESCs_Human0.54075252
122NANOG_18692474_ChIP-Seq_MEFs_Mouse0.53877999
123CTCF_27219007_Chip-Seq_Bcells_Human0.52809877
124* RBPJ_21746931_ChIP-Seq_IB4_Human0.52152544
125BCOR_27268052_Chip-Seq_Bcells_Human0.51460387
126TCF7_22412390_ChIP-Seq_EML_Mouse0.50239139
127CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.50085714
128PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.49722662
129TCF3_18692474_ChIP-Seq_MEFs_Mouse0.49706036
130* SUZ12_27294783_Chip-Seq_ESCs_Mouse0.49333936
131BMI1_23680149_ChIP-Seq_NPCS_Mouse0.48180923
132MYB_21317192_ChIP-Seq_ERMYB_Mouse0.48138057
133ELK1_22589737_ChIP-Seq_MCF10A_Human0.48086525

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier7.24656886
2MP0010234_abnormal_vibrissa_follicle5.75195759
3MP0003941_abnormal_skin_development5.33385379
4MP0005275_abnormal_skin_tensile4.52807998
5MP0005501_abnormal_skin_physiology4.41415521
6MP0004381_abnormal_hair_follicle4.05688988
7MP0000383_abnormal_hair_follicle3.74965926
8MP0010678_abnormal_skin_adnexa3.56466795
9MP0002254_reproductive_system_inflammat3.41119336
10MP0002060_abnormal_skin_morphology3.39360123
11MP0001216_abnormal_epidermal_layer3.37170700
12MP0002098_abnormal_vibrissa_morphology3.30082068
13MP0000579_abnormal_nail_morphology3.09343078
14MP0003453_abnormal_keratinocyte_physiol3.04044259
15MP0010771_integument_phenotype2.90363197
16MP0000566_synostosis2.85472930
17MP0000647_abnormal_sebaceous_gland2.59271198
18MP0002009_preneoplasia2.48651171
19MP0000467_abnormal_esophagus_morphology2.47394589
20MP0000377_abnormal_hair_follicle2.45741049
21MP0009780_abnormal_chondrocyte_physiolo2.33046221
22MP0004947_skin_inflammation2.31277038
23MP0000762_abnormal_tongue_morphology1.93174432
24MP0003566_abnormal_cell_adhesion1.92706392
25MP0000427_abnormal_hair_cycle1.92370742
26MP0001346_abnormal_lacrimal_gland1.91579051
27MP0005451_abnormal_body_composition1.87868942
28MP0009379_abnormal_foot_pigmentation1.86224215
29MP0009931_abnormal_skin_appearance1.69339143
30MP0001191_abnormal_skin_condition1.59490155
31MP0005083_abnormal_biliary_tract1.57220304
32MP0003705_abnormal_hypodermis_morpholog1.44058226
33MP0000367_abnormal_coat/_hair1.37501034
34MP0000678_abnormal_parathyroid_gland1.35723017
35MP0002234_abnormal_pharynx_morphology1.34160817
36MP0001851_eye_inflammation1.30038767
37MP0004782_abnormal_surfactant_physiolog1.26064488
38MP0001243_abnormal_dermal_layer1.25099590
39MP0010352_gastrointestinal_tract_polyps1.23998490
40MP0008875_abnormal_xenobiotic_pharmacok1.12659193
41MP0004185_abnormal_adipocyte_glucose1.10615414
42MP0000465_gastrointestinal_hemorrhage1.10525296
43MP0002006_tumorigenesis1.06674326
44MP0002166_altered_tumor_susceptibility1.06425287
45MP0000537_abnormal_urethra_morphology1.06285001
46MP0004043_abnormal_pH_regulation1.04598814
47MP0001340_abnormal_eyelid_morphology1.01293581
48MP0003950_abnormal_plasma_membrane0.95741833
49MP0004264_abnormal_extraembryonic_tissu0.95674192
50MP0002877_abnormal_melanocyte_morpholog0.95131423
51MP0003191_abnormal_cellular_cholesterol0.94907874
52MP0009053_abnormal_anal_canal0.93747872
53MP0003878_abnormal_ear_physiology0.93669977
54MP0005377_hearing/vestibular/ear_phenot0.93669977
55MP0005023_abnormal_wound_healing0.90414310
56MP0000627_abnormal_mammary_gland0.89664699
57MP0010030_abnormal_orbit_morphology0.87827039
58MP0003315_abnormal_perineum_morphology0.82590864
59MP0005075_abnormal_melanosome_morpholog0.81658394
60MP0003045_fibrosis0.78540942
61MP0008004_abnormal_stomach_pH0.77571632
62MP0003136_yellow_coat_color0.76214926
63MP0002277_abnormal_respiratory_mucosa0.71366182
64MP0008260_abnormal_autophagy0.70554638
65MP0001765_abnormal_ion_homeostasis0.70213874
66MP0003011_delayed_dark_adaptation0.69458122
67MP0003436_decreased_susceptibility_to0.69139861
68MP0005076_abnormal_cell_differentiation0.67434777
69MP0003091_abnormal_cell_migration0.66252708
70MP0005367_renal/urinary_system_phenotyp0.66224382
71MP0000516_abnormal_urinary_system0.66224382
72MP0004272_abnormal_basement_membrane0.65656938
73MP0004019_abnormal_vitamin_homeostasis0.65396515
74MP0001849_ear_inflammation0.64925148
75MP0002177_abnormal_outer_ear0.63344078
76MP0003763_abnormal_thymus_physiology0.62590874
77MP0000462_abnormal_digestive_system0.62147784
78MP0009384_cardiac_valve_regurgitation0.60239987
79MP0002896_abnormal_bone_mineralization0.60224962
80MP0008789_abnormal_olfactory_epithelium0.59262325
81MP0002148_abnormal_hypersensitivity_rea0.59192459
82MP0002095_abnormal_skin_pigmentation0.57356674
83MP0002249_abnormal_larynx_morphology0.57113555
84MP0002132_abnormal_respiratory_system0.56764655
85MP0005164_abnormal_response_to0.56706496
86MP0001958_emphysema0.56257635
87MP0001666_abnormal_nutrient_absorption0.54602774
88MP0002168_other_aberrant_phenotype0.54314673
89MP0005409_darkened_coat_color0.53783941
90MP0001784_abnormal_fluid_regulation0.53419256
91MP0003300_gastrointestinal_ulcer0.52443313
92MP0000470_abnormal_stomach_morphology0.51698986
93MP0002282_abnormal_trachea_morphology0.51241885
94MP0005623_abnormal_meninges_morphology0.50919476
95MP0000613_abnormal_salivary_gland0.48812499
96MP0002089_abnormal_postnatal_growth/wei0.48562115
97MP0005666_abnormal_adipose_tissue0.48207207
98MP0006138_congestive_heart_failure0.47586059
99MP0003638_abnormal_response/metabolism_0.46840983
100MP0001853_heart_inflammation0.46494752
101MP0002233_abnormal_nose_morphology0.44654246
102MP0003828_pulmonary_edema0.44547444
103MP0001727_abnormal_embryo_implantation0.44357092
104MP0010155_abnormal_intestine_physiology0.44015150
105MP0000538_abnormal_urinary_bladder0.44001682
106MP0005165_increased_susceptibility_to0.43393367
107MP0005248_abnormal_Harderian_gland0.43351547
108MP0009643_abnormal_urine_homeostasis0.43176187
109MP0006054_spinal_hemorrhage0.41992859
110MP0005621_abnormal_cell_physiology0.41631265
111MP0005375_adipose_tissue_phenotype0.41355478
112MP0003724_increased_susceptibility_to0.40802150
113MP0002111_abnormal_tail_morphology0.40228021
114MP0005508_abnormal_skeleton_morphology0.39934670
115MP0005408_hypopigmentation0.39174343
116MP0009840_abnormal_foam_cell0.38929885
117MP0004883_abnormal_blood_vessel0.38568844
118MP0005257_abnormal_intraocular_pressure0.38508468
119MP0003755_abnormal_palate_morphology0.38263551
120MP0001873_stomach_inflammation0.31086878
121MP0003936_abnormal_reproductive_system0.30572806
122MP0000685_abnormal_immune_system0.30341829
123MP0005390_skeleton_phenotype0.29899111
124MP0001881_abnormal_mammary_gland0.29184195
125MP0001545_abnormal_hematopoietic_system0.29111273
126MP0005397_hematopoietic_system_phenotyp0.29111273
127MP0002136_abnormal_kidney_physiology0.28803302
128MP0000858_altered_metastatic_potential0.28613816
129MP0000432_abnormal_head_morphology0.28354344
130MP0000477_abnormal_intestine_morphology0.27140688
131MP0005025_abnormal_response_to0.25666387
132MP0003938_abnormal_ear_development0.24253345
133MP0003448_altered_tumor_morphology0.24172838

Predicted human phenotypes

RankGene SetZ-score
1Hypotrichosis (HP:0001006)7.54540100
2Onycholysis (HP:0001806)6.64500028
3Lip pit (HP:0100267)6.37410706
4Parakeratosis (HP:0001036)6.30630969
5Plantar hyperkeratosis (HP:0007556)6.22175938
6Woolly hair (HP:0002224)6.01802043
7Congenital ichthyosiform erythroderma (HP:0007431)5.94098092
8Right ventricular cardiomyopathy (HP:0011663)5.91957961
9Fragile nails (HP:0001808)5.89918469
10Increased IgE level (HP:0003212)5.66388001
11Congenital nonbullous ichthyosiform erythroderma (HP:0007479)5.63690320
12Milia (HP:0001056)5.40277880
13Palmoplantar hyperkeratosis (HP:0000972)5.26313067
14Palmar hyperkeratosis (HP:0010765)4.95466623
15Erythema (HP:0010783)4.91676202
16Abnormality of nail color (HP:0100643)4.72938093
17Pili torti (HP:0003777)4.46426574
18Erythroderma (HP:0001019)4.36853170
19Abnormal blistering of the skin (HP:0008066)4.13091563
20Nail dystrophy (HP:0008404)4.09512651
21Popliteal pterygium (HP:0009756)3.92624900
22Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.90255592
23Ectropion (HP:0000656)3.81949598
24Chronic bronchitis (HP:0004469)3.75622374
25Corneal erosion (HP:0200020)3.74846429
26Sparse eyelashes (HP:0000653)3.69485261
27Thick nail (HP:0001805)3.64599139
28Natal tooth (HP:0000695)3.43289607
29Atrophic scars (HP:0001075)3.40034815
30Abnormality of the axillary hair (HP:0100134)3.39912075
31Abnormality of secondary sexual hair (HP:0009888)3.39912075
32Abnormality of cells of the erythroid lineage (HP:0012130)3.37362894
33Sparse scalp hair (HP:0002209)3.33872434
34Reticulocytopenia (HP:0001896)3.33472001
35Hypohidrosis (HP:0000966)3.32040140
36Acanthosis nigricans (HP:0000956)3.27861502
37Curly hair (HP:0002212)3.25858175
38Selective tooth agenesis (HP:0001592)3.17564493
39Advanced eruption of teeth (HP:0006288)3.16088406
40Hyperactive renin-angiotensin system (HP:0000841)3.15733276
41Gangrene (HP:0100758)3.07674739
42Abnormal respiratory motile cilium physiology (HP:0012261)3.06213167
43Pruritus (HP:0000989)3.05007651
44Absent eyelashes (HP:0000561)2.99860857
45Abnormal number of erythroid precursors (HP:0012131)2.96444628
46Abnormal respiratory epithelium morphology (HP:0012253)2.95771432
47Abnormal respiratory motile cilium morphology (HP:0005938)2.95771432
48Distal lower limb muscle weakness (HP:0009053)2.95727434
49Rhinitis (HP:0012384)2.93761956
50Oligodontia (HP:0000677)2.91124855
51Ventricular tachycardia (HP:0004756)2.89538002
52Hypoplastic labia majora (HP:0000059)2.88896177
53Abnormality of the salivary glands (HP:0010286)2.88382249
54Abnormality of the dental root (HP:0006486)2.87175252
55Taurodontia (HP:0000679)2.87175252
56Abnormality of permanent molar morphology (HP:0011071)2.87175252
57Alopecia of scalp (HP:0002293)2.85076631
58Oral leukoplakia (HP:0002745)2.82899307
59Abnormal ciliary motility (HP:0012262)2.79470130
60Ridged nail (HP:0001807)2.78782022
61Conjunctival hamartoma (HP:0100780)2.77886888
62Palmoplantar keratoderma (HP:0000982)2.76277112
63Absent/shortened dynein arms (HP:0200106)2.72910301
64Dynein arm defect of respiratory motile cilia (HP:0012255)2.72910301
65Abnormal hair laboratory examination (HP:0003328)2.70055292
66Abnormality of molar morphology (HP:0011070)2.65448182
67Abnormality of molar (HP:0011077)2.65448182
68Pterygium (HP:0001059)2.63870098
69Nasal polyposis (HP:0100582)2.63261525
70Abnormality of the labia majora (HP:0012881)2.61490098
71Blepharitis (HP:0000498)2.57959723
72Abnormal hemoglobin (HP:0011902)2.57618496
73Abnormality of the dental pulp (HP:0006479)2.52315537
74Hyporeflexia of lower limbs (HP:0002600)2.51919740
75Hypoplasia of dental enamel (HP:0006297)2.47854898
76Aplasia cutis congenita (HP:0001057)2.47542542
77Dehydration (HP:0001944)2.44396066
78Pustule (HP:0200039)2.40432580
79Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)2.38012096
80Bronchiectasis (HP:0002110)2.36822426
81Malnutrition (HP:0004395)2.31723088
82Concave nail (HP:0001598)2.31466470
83Abnormality of the gastric mucosa (HP:0004295)2.30038718
84Anhidrosis (HP:0000970)2.28352617
85Congenital, generalized hypertrichosis (HP:0004540)2.27711691
86Short nail (HP:0001799)2.26320650
87Ankyloglossia (HP:0010296)2.23864846
88Macrocytic anemia (HP:0001972)2.18200367
89Abnormality of the neuromuscular junction (HP:0003398)2.14586531
90Fatigable weakness (HP:0003473)2.14586531
91Abnormality of the nasal mucosa (HP:0000433)2.14212484
92Hypodontia (HP:0000668)2.09998002
93Renal salt wasting (HP:0000127)2.04859330
94Conical tooth (HP:0000698)2.01118542
95Dry skin (HP:0000958)2.00972800
96Flat acetabular roof (HP:0003180)1.99960684
97Down-sloping shoulders (HP:0200021)1.98205518
98Skin ulcer (HP:0200042)1.97005276
99Nasolacrimal duct obstruction (HP:0000579)1.95396820
100Pallor (HP:0000980)1.93085773
101Brittle hair (HP:0002299)1.92934211
102Septate vagina (HP:0001153)1.91603669
103Vascular calcification (HP:0004934)1.91069819
104Abnormality of the distal phalanges of the toes (HP:0010182)1.89416363
105Stenosis of the external auditory canal (HP:0000402)1.88781416
106Hypoplasia of the uterus (HP:0000013)1.88451302
107Aplasia/hypoplasia of the uterus (HP:0008684)1.88291373
108Areflexia of lower limbs (HP:0002522)1.88223477
109Dry hair (HP:0011359)1.80455270
110Hypergammaglobulinemia (HP:0010702)1.78591539
111Labial hypoplasia (HP:0000066)1.77726773
112Esophageal atresia (HP:0002032)1.76427963
113Fragile skin (HP:0001030)1.75469585
114Skin pits (HP:0100276)1.75453243
115Broad face (HP:0000283)1.73651757
116Interstitial pulmonary disease (HP:0006530)1.73610190
117Hypoparathyroidism (HP:0000829)1.73462709
118Severe Myopia (HP:0011003)1.73389571
119Abnormality of oral frenula (HP:0000190)1.72943510
120Arterial tortuosity (HP:0005116)1.72057341
121Absent eyebrow (HP:0002223)1.71317363
122Bifid scrotum (HP:0000048)1.71035153
123Anonychia (HP:0001798)1.69769016
124Hyperhidrosis (HP:0000975)1.69233332
125Male infertility (HP:0003251)1.68834710
126Polygenic inheritance (HP:0010982)1.67776560
127Carious teeth (HP:0000670)1.67711159
128Bronchitis (HP:0012387)1.67382284
129Lack of skin elasticity (HP:0100679)1.66419856
130Amelogenesis imperfecta (HP:0000705)1.66093257
131Absent hair (HP:0002298)1.65830859
132Hypoplastic female external genitalia (HP:0012815)1.62455931
133Ulnar claw (HP:0001178)1.61341015
134Aplasia involving bones of the extremities (HP:0009825)1.59491020
135Aplasia involving bones of the upper limbs (HP:0009823)1.59491020
136Aplasia of the phalanges of the hand (HP:0009802)1.59491020
137Trismus (HP:0000211)1.58134712
138Malignant hyperthermia (HP:0002047)1.49769963

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST45.53373442
2MAPKAPK34.72404333
3MAP3K34.72070217
4MST1R4.38017752
5EPHA24.28877579
6RPS6KB23.22443224
7FER3.05547141
8MAP3K22.60273551
9SIK12.44622936
10TRPM72.44263729
11MAPKAPK52.20508234
12EPHB22.18931957
13PIM22.17734342
14LRRK22.02505242
15SMG12.00120075
16ERBB31.91977662
17STK101.87430605
18LATS11.80788113
19LMTK21.68500110
20MAP3K61.50714772
21MAP3K91.48251805
22TGFBR21.39468782
23MAP2K31.37492950
24PAK41.34874246
25MAP3K141.29041626
26EPHA31.25639073
27LATS21.24341559
28EEF2K1.22580266
29MAP3K11.19988167
30PKN21.17045977
31GRK11.16507113
32TAOK11.14027103
33STK241.10942059
34MAP3K111.10828768
35TESK11.08709696
36MAP2K21.07940735
37PTK61.07732384
38MET1.06561315
39MAP2K61.03703830
40ERN10.99706311
41FGFR40.98359413
42MAPK150.96605771
43BLK0.95791639
44STK380.93093284
45NEK60.92187606
46PIK3CG0.91971921
47IKBKE0.91536480
48RIPK40.90048376
49FGFR20.89528698
50MAPKAPK20.88549339
51SIK30.88438284
52MAP3K120.87872900
53PBK0.85136315
54NTRK10.84156964
55DMPK0.84002397
56EPHB10.83190297
57DYRK1B0.82760562
58ARAF0.82111466
59IRAK30.81888584
60RPS6KA40.81219010
61FGFR30.81056160
62TYK20.80026919
63STK38L0.77486349
64CDK60.75520113
65RIPK10.72203086
66IKBKB0.71932732
67TNK20.69474230
68CDK120.68427895
69ICK0.67980480
70RPS6KA20.66610482
71DYRK30.65804423
72TGFBR10.65712860
73BCR0.65699841
74MTOR0.61358666
75ERBB20.61131612
76MYLK0.60770973
77PTK20.56839615
78MATK0.56808071
79PRKCI0.56787196
80PDGFRA0.56752611
81CDK190.56403952
82NME20.55642881
83NLK0.55430453
84MAP3K130.53116359
85ITK0.52208001
86GRK70.51619130
87SCYL20.50698305
88TBK10.50200854
89EIF2AK10.50177505
90MAP3K70.49394470
91TEC0.48337396
92BTK0.47169432
93PDGFRB0.46900781
94EIF2AK20.45985452
95CHUK0.44379419
96FGFR10.43750567
97ILK0.42683002
98PRKD20.42212851
99CDK30.39849136
100RPS6KA10.38639661
101CDC42BPA0.37716229
102BMX0.35564461
103MARK20.35354957
104PRKD10.34574566
105PRKCE0.33740775
106CAMK2G0.32650673
107TAOK20.32055574
108HCK0.31706080
109ABL20.31705032
110RPS6KA50.31577214
111GRK60.30128439
112MAP2K10.30022008
113SGK30.30005176
114TTN0.30000224
115BMPR1B0.29739222
116ABL10.29692985
117RET0.29643006
118TIE10.29598388
119CDK80.29256953
120MUSK0.28925798
121MAPK40.28605734
122TRIB30.28232999
123OXSR10.28199587
124RPS6KC10.28111433
125RPS6KL10.28111433
126ZAP700.27941689
127MKNK10.27881522
128ROCK20.26889766
129PRKCD0.26002522
130NME10.25852583
131ERBB40.25659834
132NEK90.24827935
133LIMK10.24639638
134JAK20.24506311
135MAP3K50.24377482
136STK30.24232029
137RPS6KA60.23720047
138ADRBK10.23613984
139HIPK20.23524284
140PIK3CA0.23099552
141GSK3A0.22144348
142IRAK10.21835945
143ROCK10.20889993
144CDK70.18953105
145PDPK10.18925949
146RPS6KB10.18713985

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.87261848
2Cyanoamino acid metabolism_Homo sapiens_hsa004603.95009593
3Sphingolipid metabolism_Homo sapiens_hsa006003.46115205
4Arachidonic acid metabolism_Homo sapiens_hsa005902.69204462
5Linoleic acid metabolism_Homo sapiens_hsa005912.58523165
6alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.49094193
7Pathogenic Escherichia coli infection_Homo sapiens_hsa051302.43509719
8Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.24795164
9Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.20756039
10Phenylalanine metabolism_Homo sapiens_hsa003602.05692934
11Histidine metabolism_Homo sapiens_hsa003402.05466112
12Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.01474377
13Basal cell carcinoma_Homo sapiens_hsa052171.95163387
14Chemical carcinogenesis_Homo sapiens_hsa052041.88281696
15Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.74282191
16ECM-receptor interaction_Homo sapiens_hsa045121.73121316
17Tight junction_Homo sapiens_hsa045301.55649424
18p53 signaling pathway_Homo sapiens_hsa041151.53479697
19Leukocyte transendothelial migration_Homo sapiens_hsa046701.52500048
20Bladder cancer_Homo sapiens_hsa052191.52402305
21Adherens junction_Homo sapiens_hsa045201.50637932
22Retinol metabolism_Homo sapiens_hsa008301.48748761
23Fatty acid elongation_Homo sapiens_hsa000621.47848799
24Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.43699701
25Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.43552398
26Ether lipid metabolism_Homo sapiens_hsa005651.42145780
27Glutathione metabolism_Homo sapiens_hsa004801.39235610
28Hippo signaling pathway_Homo sapiens_hsa043901.37228100
29Pancreatic cancer_Homo sapiens_hsa052121.34446449
30Chronic myeloid leukemia_Homo sapiens_hsa052201.33619876
31Hedgehog signaling pathway_Homo sapiens_hsa043401.23822921
32Small cell lung cancer_Homo sapiens_hsa052221.22523291
33Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.22226687
34Proteoglycans in cancer_Homo sapiens_hsa052051.21497548
35Renal cell carcinoma_Homo sapiens_hsa052111.19597566
36Thyroid cancer_Homo sapiens_hsa052161.16945230
37VEGF signaling pathway_Homo sapiens_hsa043701.16451322
38Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.15614429
39Hepatitis C_Homo sapiens_hsa051601.15386185
40Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.13032556
41Vibrio cholerae infection_Homo sapiens_hsa051101.11997480
42Amoebiasis_Homo sapiens_hsa051461.10317745
43Toxoplasmosis_Homo sapiens_hsa051451.08999146
44Central carbon metabolism in cancer_Homo sapiens_hsa052301.08994313
45Tyrosine metabolism_Homo sapiens_hsa003501.07060722
46Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.06988204
47Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.06358804
48Endocytosis_Homo sapiens_hsa041441.06321997
49Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.05046593
50Jak-STAT signaling pathway_Homo sapiens_hsa046301.00152404
51Fructose and mannose metabolism_Homo sapiens_hsa000510.98684944
52Choline metabolism in cancer_Homo sapiens_hsa052310.98550473
53Sphingolipid signaling pathway_Homo sapiens_hsa040710.97256942
54Pertussis_Homo sapiens_hsa051330.94567555
55MicroRNAs in cancer_Homo sapiens_hsa052060.92992267
56Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.91919328
57Galactose metabolism_Homo sapiens_hsa000520.91182915
58Pentose phosphate pathway_Homo sapiens_hsa000300.89671842
59Melanogenesis_Homo sapiens_hsa049160.89634332
60Lysosome_Homo sapiens_hsa041420.89383464
61Steroid biosynthesis_Homo sapiens_hsa001000.89011607
62Platelet activation_Homo sapiens_hsa046110.81879460
63NOD-like receptor signaling pathway_Homo sapiens_hsa046210.81459122
64Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.81386643
65ABC transporters_Homo sapiens_hsa020100.81180158
66Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.80755564
67Axon guidance_Homo sapiens_hsa043600.79387008
68Mineral absorption_Homo sapiens_hsa049780.78000183
69Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.77778195
70Hematopoietic cell lineage_Homo sapiens_hsa046400.77685200
71Insulin signaling pathway_Homo sapiens_hsa049100.77392301
72Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.77354012
73Glioma_Homo sapiens_hsa052140.74846913
74Caffeine metabolism_Homo sapiens_hsa002320.73991462
75Acute myeloid leukemia_Homo sapiens_hsa052210.73221968
76GnRH signaling pathway_Homo sapiens_hsa049120.72613844
77Thyroid hormone signaling pathway_Homo sapiens_hsa049190.71684217
78Phosphatidylinositol signaling system_Homo sapiens_hsa040700.71259773
79TGF-beta signaling pathway_Homo sapiens_hsa043500.68816932
80Transcriptional misregulation in cancer_Homo sapiens_hsa052020.68776789
81TNF signaling pathway_Homo sapiens_hsa046680.68139053
82Non-small cell lung cancer_Homo sapiens_hsa052230.66939008
83Estrogen signaling pathway_Homo sapiens_hsa049150.65877390
84Insulin resistance_Homo sapiens_hsa049310.65632331
85Glycosaminoglycan degradation_Homo sapiens_hsa005310.65473762
86AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.64482749
87Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.62811362
88Vitamin digestion and absorption_Homo sapiens_hsa049770.62457589
89beta-Alanine metabolism_Homo sapiens_hsa004100.62447004
90Neurotrophin signaling pathway_Homo sapiens_hsa047220.60952501
91Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.60664197
92Pathways in cancer_Homo sapiens_hsa052000.60623406
93Leishmaniasis_Homo sapiens_hsa051400.57763636
94Staphylococcus aureus infection_Homo sapiens_hsa051500.57102414
95Pancreatic secretion_Homo sapiens_hsa049720.55908244
96Wnt signaling pathway_Homo sapiens_hsa043100.55735147
97Salmonella infection_Homo sapiens_hsa051320.54695422
98N-Glycan biosynthesis_Homo sapiens_hsa005100.51992817
99Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.51150714
100Notch signaling pathway_Homo sapiens_hsa043300.50922325
101Prolactin signaling pathway_Homo sapiens_hsa049170.50387722
102Apoptosis_Homo sapiens_hsa042100.49476636
103Protein digestion and absorption_Homo sapiens_hsa049740.49122972
104AMPK signaling pathway_Homo sapiens_hsa041520.48525177
105Rap1 signaling pathway_Homo sapiens_hsa040150.48232750
106Phototransduction_Homo sapiens_hsa047440.48126405
107Pentose and glucuronate interconversions_Homo sapiens_hsa000400.47438383
108Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.47391987
109HTLV-I infection_Homo sapiens_hsa051660.46796912
110Focal adhesion_Homo sapiens_hsa045100.46724816
111Ras signaling pathway_Homo sapiens_hsa040140.46339556
112Endometrial cancer_Homo sapiens_hsa052130.46047784
113Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.45701050
114Glycerophospholipid metabolism_Homo sapiens_hsa005640.45618486
115Renin secretion_Homo sapiens_hsa049240.45334672
116Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.45221602
117Osteoclast differentiation_Homo sapiens_hsa043800.44277079
118Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.42399295
119mTOR signaling pathway_Homo sapiens_hsa041500.41606508
120Other glycan degradation_Homo sapiens_hsa005110.41469679
121Antigen processing and presentation_Homo sapiens_hsa046120.39647121
122Toll-like receptor signaling pathway_Homo sapiens_hsa046200.39421737
123Gastric acid secretion_Homo sapiens_hsa049710.39102647
124Melanoma_Homo sapiens_hsa052180.38160331
125Influenza A_Homo sapiens_hsa051640.37247228
126ErbB signaling pathway_Homo sapiens_hsa040120.37183526
127Dorso-ventral axis formation_Homo sapiens_hsa043200.37092135
128Legionellosis_Homo sapiens_hsa051340.36923229
129Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.33606051
130Collecting duct acid secretion_Homo sapiens_hsa049660.31909786
131Malaria_Homo sapiens_hsa051440.31703851
132Ovarian steroidogenesis_Homo sapiens_hsa049130.31373008
133Folate biosynthesis_Homo sapiens_hsa007900.30816949
134Prostate cancer_Homo sapiens_hsa052150.30253354
135Regulation of actin cytoskeleton_Homo sapiens_hsa048100.29558119
136Steroid hormone biosynthesis_Homo sapiens_hsa001400.29465242
137Inositol phosphate metabolism_Homo sapiens_hsa005620.28866599
138Shigellosis_Homo sapiens_hsa051310.28336644
139Circadian rhythm_Homo sapiens_hsa047100.27441344

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