TADA1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: TADA1L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)5.68788225
2central nervous system myelination (GO:0022010)5.68788225
3chaperone-mediated protein transport (GO:0072321)4.44094833
4histone H2A acetylation (GO:0043968)3.94795186
5proteasome assembly (GO:0043248)3.94096892
6L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.92908411
7DNA double-strand break processing (GO:0000729)3.92567114
8fatty acid elongation (GO:0030497)3.86115691
9mannosylation (GO:0097502)3.75829685
10respiratory chain complex IV assembly (GO:0008535)3.75480791
11DNA deamination (GO:0045006)3.66577562
12protein neddylation (GO:0045116)3.62078361
13protein deneddylation (GO:0000338)3.58455911
14transcription elongation from RNA polymerase III promoter (GO:0006385)3.54556595
15termination of RNA polymerase III transcription (GO:0006386)3.54556595
16presynaptic membrane organization (GO:0097090)3.50336229
17mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.49123512
18mitochondrial respiratory chain complex I assembly (GO:0032981)3.49123512
19NADH dehydrogenase complex assembly (GO:0010257)3.49123512
207-methylguanosine RNA capping (GO:0009452)3.40599398
21RNA capping (GO:0036260)3.40599398
22negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.33437608
237-methylguanosine mRNA capping (GO:0006370)3.29401570
24protein complex biogenesis (GO:0070271)3.28724237
25GPI anchor biosynthetic process (GO:0006506)3.26547769
26non-recombinational repair (GO:0000726)3.24529777
27double-strand break repair via nonhomologous end joining (GO:0006303)3.24529777
28deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.22871088
29cullin deneddylation (GO:0010388)3.20807099
30DNA damage response, detection of DNA damage (GO:0042769)3.16886233
31negative regulation of ligase activity (GO:0051352)3.11641209
32negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.11641209
33telomere maintenance via semi-conservative replication (GO:0032201)3.06489010
34negative regulation of DNA recombination (GO:0045910)3.06149682
35signal peptide processing (GO:0006465)3.05622378
36kinetochore assembly (GO:0051382)3.02948642
37kinetochore organization (GO:0051383)3.01665885
38nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.00907816
39DNA strand elongation involved in DNA replication (GO:0006271)3.00785049
40water-soluble vitamin biosynthetic process (GO:0042364)3.00077762
41pyrimidine nucleobase catabolic process (GO:0006208)3.00039351
42positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.99787531
43intraciliary transport (GO:0042073)2.99585085
44regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.99259953
45exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.99079157
46DNA strand elongation (GO:0022616)2.95774664
47histone exchange (GO:0043486)2.94590789
48iron-sulfur cluster assembly (GO:0016226)2.94351151
49metallo-sulfur cluster assembly (GO:0031163)2.94351151
50cytochrome complex assembly (GO:0017004)2.93810397
51positive regulation of mitotic sister chromatid separation (GO:1901970)2.91333953
52positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.91333953
53positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.91333953
54L-methionine salvage (GO:0071267)2.90981112
55L-methionine biosynthetic process (GO:0071265)2.90981112
56amino acid salvage (GO:0043102)2.90981112
57pseudouridine synthesis (GO:0001522)2.90771393
58regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.89835641
59regulation of mitotic spindle checkpoint (GO:1903504)2.89835641
60anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.88332497
61mitochondrial respiratory chain complex assembly (GO:0033108)2.86133023
62establishment of protein localization to mitochondrial membrane (GO:0090151)2.84766589
63DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.84111896
64regulation of sister chromatid cohesion (GO:0007063)2.81143244
65signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.80704652
66signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.80704652
67signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.80704652
68GPI anchor metabolic process (GO:0006505)2.80444237
69spindle checkpoint (GO:0031577)2.80080182
70intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.80027808
71signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.80027808
72regulation of cellular amino acid metabolic process (GO:0006521)2.77991311
73spliceosomal snRNP assembly (GO:0000387)2.77526576
74DNA replication initiation (GO:0006270)2.77371580
75mitotic spindle checkpoint (GO:0071174)2.76853927
76DNA replication-independent nucleosome assembly (GO:0006336)2.75860558
77DNA replication-independent nucleosome organization (GO:0034724)2.75860558
78somatic hypermutation of immunoglobulin genes (GO:0016446)2.75663478
79somatic diversification of immune receptors via somatic mutation (GO:0002566)2.75663478
80regulation of helicase activity (GO:0051095)2.75346043
81antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.75320370
82mast cell activation (GO:0045576)2.74451411
83metaphase plate congression (GO:0051310)2.74327323
84establishment of integrated proviral latency (GO:0075713)2.74020535
85protein localization to kinetochore (GO:0034501)2.73608226
86attachment of spindle microtubules to kinetochore (GO:0008608)2.73524207
87RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.71951176
88tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.71951176
89CENP-A containing nucleosome assembly (GO:0034080)2.71386959
90telomere maintenance via recombination (GO:0000722)2.70264601
91long-chain fatty acid biosynthetic process (GO:0042759)2.69971761
92C-terminal protein lipidation (GO:0006501)2.67952506
93negative regulation of mitotic sister chromatid separation (GO:2000816)2.67705983
94negative regulation of sister chromatid segregation (GO:0033046)2.67705983
95negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.67705983
96negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.67705983
97negative regulation of mitotic sister chromatid segregation (GO:0033048)2.67705983
98response to pheromone (GO:0019236)2.67061508
99regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.66956210
100regulation of mitotic metaphase/anaphase transition (GO:0030071)2.66956210
101purine nucleobase biosynthetic process (GO:0009113)2.66632560
102regulation of sister chromatid segregation (GO:0033045)2.66534293
103regulation of mitotic sister chromatid separation (GO:0010965)2.66534293
104regulation of mitotic sister chromatid segregation (GO:0033047)2.66534293
105viral mRNA export from host cell nucleus (GO:0046784)2.65980360
106histone mRNA metabolic process (GO:0008334)2.65778376
107nucleobase catabolic process (GO:0046113)2.64941996
108preassembly of GPI anchor in ER membrane (GO:0016254)2.64680601
109transcription-coupled nucleotide-excision repair (GO:0006283)2.64616044
110nonmotile primary cilium assembly (GO:0035058)2.64531761
111tRNA aminoacylation for protein translation (GO:0006418)2.63742671
112lactate metabolic process (GO:0006089)2.61722285
113L-serine metabolic process (GO:0006563)2.61482473
114positive regulation of protein homodimerization activity (GO:0090073)2.61414557
115amino acid activation (GO:0043038)2.61400558
116tRNA aminoacylation (GO:0043039)2.61400558
117DNA integration (GO:0015074)2.61348581
118platelet dense granule organization (GO:0060155)2.61257100
119DNA replication-dependent nucleosome organization (GO:0034723)2.61103602
120DNA replication-dependent nucleosome assembly (GO:0006335)2.61103602
121signal transduction involved in DNA integrity checkpoint (GO:0072401)2.60225073
122signal transduction involved in DNA damage checkpoint (GO:0072422)2.60225073
123negative regulation of chromosome segregation (GO:0051985)2.59768598
124IMP biosynthetic process (GO:0006188)2.59254367
125DNA catabolic process, exonucleolytic (GO:0000738)2.58504964
126signal transduction involved in cell cycle checkpoint (GO:0072395)2.58121263
127positive regulation of mitochondrial fission (GO:0090141)2.57432783
128mitochondrial RNA metabolic process (GO:0000959)2.57186696
129mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.57010305
130mitotic spindle assembly checkpoint (GO:0007094)2.55478862
131mitotic metaphase plate congression (GO:0007080)2.55064650
132replication fork processing (GO:0031297)2.54998261
133negative regulation of DNA-dependent DNA replication (GO:2000104)2.54810393
134resolution of meiotic recombination intermediates (GO:0000712)2.54282756
135deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.53818229
136isoprenoid biosynthetic process (GO:0008299)2.53557870
137DNA ligation (GO:0006266)2.53406412
138spindle assembly checkpoint (GO:0071173)2.52972248
139C-terminal protein amino acid modification (GO:0018410)2.52653925
140regulation of centriole replication (GO:0046599)2.52136579
141antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.52074982
142neurotransmitter uptake (GO:0001504)2.52058687
143branched-chain amino acid catabolic process (GO:0009083)2.51888910
144cholesterol biosynthetic process (GO:0006695)2.49810397
145maturation of 5.8S rRNA (GO:0000460)2.49746056
146negative regulation of neurotransmitter transport (GO:0051589)2.43708783
147negative regulation of transcription by competitive promoter binding (GO:0010944)2.42137684
148energy coupled proton transport, down electrochemical gradient (GO:0015985)2.41201118
149ATP synthesis coupled proton transport (GO:0015986)2.41201118
150mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.39991359
151prenylation (GO:0097354)2.39713585
152protein prenylation (GO:0018342)2.39713585
153protein targeting to mitochondrion (GO:0006626)2.39501096
154lymphoid progenitor cell differentiation (GO:0002320)2.39332298
155positive regulation of ligase activity (GO:0051351)2.39283097
156positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.37690771
157transcription elongation from RNA polymerase I promoter (GO:0006362)2.37643205
158positive regulation of granulocyte differentiation (GO:0030854)2.36814402
159presynaptic membrane assembly (GO:0097105)2.35588672
160pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.34478154
161chromatin remodeling at centromere (GO:0031055)2.33863030
162DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.33043086
163histone H2B ubiquitination (GO:0033523)2.32069462
164nucleotide-excision repair, DNA gap filling (GO:0006297)2.30857514
165mitotic recombination (GO:0006312)2.30719359
166tRNA processing (GO:0008033)2.30547987
167telomere maintenance via telomere lengthening (GO:0010833)2.30009775
168spermatid nucleus differentiation (GO:0007289)2.28777973
169dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.27918903

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.91097396
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.81246605
3NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.75393607
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.41834247
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.24651931
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.17604981
7E2F7_22180533_ChIP-Seq_HELA_Human3.10902585
8HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.89822336
9* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.84071946
10ELF1_17652178_ChIP-ChIP_JURKAT_Human2.77852011
11ZNF274_21170338_ChIP-Seq_K562_Hela2.74778583
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.63154555
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.57098017
14PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.38085642
15HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.35949095
16THAP11_20581084_ChIP-Seq_MESCs_Mouse2.34527091
17SRF_21415370_ChIP-Seq_HL-1_Mouse2.31917383
18E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.29454029
19VDR_23849224_ChIP-Seq_CD4+_Human2.25616633
20SALL1_21062744_ChIP-ChIP_HESCs_Human2.23344565
21CREB1_15753290_ChIP-ChIP_HEK293T_Human2.21891688
22SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.19516960
23FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.15348964
24IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.12109903
25FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.10060754
26CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.07557988
27HOXB4_20404135_ChIP-ChIP_EML_Mouse1.98238348
28MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.95848850
29* FOXP3_21729870_ChIP-Seq_TREG_Human1.92197754
30SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.91903702
31MYC_18358816_ChIP-ChIP_MESCs_Mouse1.85829256
32TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.77131924
33* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.76599115
34MYC_18555785_ChIP-Seq_MESCs_Mouse1.75449775
35GBX2_23144817_ChIP-Seq_PC3_Human1.74578438
36IRF8_21731497_ChIP-ChIP_J774_Mouse1.70719364
37GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.66780259
38EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.66082399
39KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.62896029
40E2F4_17652178_ChIP-ChIP_JURKAT_Human1.61401625
41CTBP2_25329375_ChIP-Seq_LNCAP_Human1.60310193
42DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.59161224
43P300_19829295_ChIP-Seq_ESCs_Human1.58345266
44ELK1_19687146_ChIP-ChIP_HELA_Human1.58186578
45GABP_19822575_ChIP-Seq_HepG2_Human1.55720247
46NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.55228512
47DCP1A_22483619_ChIP-Seq_HELA_Human1.52741150
48YY1_21170310_ChIP-Seq_MESCs_Mouse1.51442832
49GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.50891868
50YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.49994058
51TAF15_26573619_Chip-Seq_HEK293_Human1.47841292
52MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.46884362
53ZFP57_27257070_Chip-Seq_ESCs_Mouse1.43589887
54LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.41874595
55MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.39440612
56* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.39050594
57FOXM1_23109430_ChIP-Seq_U2OS_Human1.38619587
58MYC_19030024_ChIP-ChIP_MESCs_Mouse1.36016848
59E2F1_18555785_ChIP-Seq_MESCs_Mouse1.34768251
60ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.32569702
61CTBP1_25329375_ChIP-Seq_LNCAP_Human1.30913697
62TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.30098127
63SCL_19346495_ChIP-Seq_HPC-7_Human1.29192815
64XRN2_22483619_ChIP-Seq_HELA_Human1.28909199
65* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.28440002
66IRF1_19129219_ChIP-ChIP_H3396_Human1.27495886
67SPI1_23547873_ChIP-Seq_NB4_Human1.27299186
68GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.25099308
69PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.23589910
70CIITA_25753668_ChIP-Seq_RAJI_Human1.21804116
71CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.20289365
72SOX2_16153702_ChIP-ChIP_HESCs_Human1.19588306
73POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.19423069
74TTF2_22483619_ChIP-Seq_HELA_Human1.15832592
75E2F1_21310950_ChIP-Seq_MCF-7_Human1.15646434
76RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.15317382
77CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.14897189
78POU3F2_20337985_ChIP-ChIP_501MEL_Human1.13347524
79NANOG_16153702_ChIP-ChIP_HESCs_Human1.13168763
80MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.12881489
81EWS_26573619_Chip-Seq_HEK293_Human1.12729028
82CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.12576339
83RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.11378328
84MYC_18940864_ChIP-ChIP_HL60_Human1.09957495
85FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.08776642
86EZH2_22144423_ChIP-Seq_EOC_Human1.07713434
87STAT4_19710469_ChIP-ChIP_TH1__Mouse1.05853205
88RNF2_27304074_Chip-Seq_NSC_Mouse1.05191665
89MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.02423599
90PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.02263110
91PCGF2_27294783_Chip-Seq_ESCs_Mouse1.02223396
92OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01175092
93GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.00229720
94UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.00172816
95TP53_22573176_ChIP-Seq_HFKS_Human0.99027159
96CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.98960548
97MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.98924842
98* IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.98648175
99* CBP_20019798_ChIP-Seq_JUKART_Human0.98648175
100NELFA_20434984_ChIP-Seq_ESCs_Mouse0.97637334
101POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.96372987
102RBPJ_22232070_ChIP-Seq_NCS_Mouse0.95014146
103ER_23166858_ChIP-Seq_MCF-7_Human0.94106812
104* KLF5_20875108_ChIP-Seq_MESCs_Mouse0.93430605
105FLI1_27457419_Chip-Seq_LIVER_Mouse0.93218601
106FUS_26573619_Chip-Seq_HEK293_Human0.93142611
107FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.92914661
108LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.92422440
109HTT_18923047_ChIP-ChIP_STHdh_Human0.91634498
110AR_21909140_ChIP-Seq_LNCAP_Human0.91424137
111FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90951014
112* EZH2_27294783_Chip-Seq_NPCs_Mouse0.90147467
113SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.89343161
114BP1_19119308_ChIP-ChIP_Hs578T_Human0.88336624
115TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88309905
116POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.88309905
117PADI4_21655091_ChIP-ChIP_MCF-7_Human0.87765787
118MYC_19079543_ChIP-ChIP_MESCs_Mouse0.86010538
119* STAT3_18555785_Chip-Seq_ESCs_Mouse0.84948879
120AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.84828596
121IGF1R_20145208_ChIP-Seq_DFB_Human0.84608914
122VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.82497414
123NOTCH1_21737748_ChIP-Seq_TLL_Human0.82373314
124* NFE2_27457419_Chip-Seq_LIVER_Mouse0.81984535
125LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.81586139
126* SUZ12_27294783_Chip-Seq_NPCs_Mouse0.81301298
127VDR_22108803_ChIP-Seq_LS180_Human0.80356092
128* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.79958564
129SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.79843591
130IRF8_22096565_ChIP-ChIP_GC-B_Human0.78895475
131FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.78885063
132* SUZ12_18555785_Chip-Seq_ESCs_Mouse0.78400686
133MYCN_18555785_ChIP-Seq_MESCs_Mouse0.78157092
134POU5F1_16153702_ChIP-ChIP_HESCs_Human0.78029537
135CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.77424321
136* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.77195289
137E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.77146193
138* RUNX1_27457419_Chip-Seq_LIVER_Mouse0.76772868

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001529_abnormal_vocalization3.51365527
2MP0003880_abnormal_central_pattern3.27485611
3MP0001905_abnormal_dopamine_level2.70745942
4MP0005423_abnormal_somatic_nervous2.62264500
5MP0008057_abnormal_DNA_replication2.57532508
6MP0003122_maternal_imprinting2.43029791
7MP0008789_abnormal_olfactory_epithelium2.30172415
8MP0005671_abnormal_response_to2.29444464
9MP0002822_catalepsy2.27041038
10MP0005394_taste/olfaction_phenotype2.21202793
11MP0005499_abnormal_olfactory_system2.21202793
12MP0004142_abnormal_muscle_tone2.18401059
13MP0000920_abnormal_myelination2.16051272
14MP0006292_abnormal_olfactory_placode2.13066023
15MP0000566_synostosis2.05737553
16MP0002396_abnormal_hematopoietic_system2.05666914
17MP0008260_abnormal_autophagy1.99836504
18MP0005075_abnormal_melanosome_morpholog1.91881492
19MP0001835_abnormal_antigen_presentation1.89536831
20MP0008058_abnormal_DNA_repair1.88859351
21MP0006072_abnormal_retinal_apoptosis1.87844719
22MP0001986_abnormal_taste_sensitivity1.87547208
23MP0003763_abnormal_thymus_physiology1.78290564
24MP0005646_abnormal_pituitary_gland1.78130857
25MP0003718_maternal_effect1.74872370
26MP0001293_anophthalmia1.73808434
27MP0009785_altered_susceptibility_to1.66661623
28MP0004147_increased_porphyrin_level1.66123005
29MP0009697_abnormal_copulation1.64415881
30MP0004859_abnormal_synaptic_plasticity1.63733288
31MP0010094_abnormal_chromosome_stability1.63711108
32MP0002272_abnormal_nervous_system1.61748557
33MP0003787_abnormal_imprinting1.61374740
34MP0002736_abnormal_nociception_after1.55536981
35MP0008877_abnormal_DNA_methylation1.54798480
36MP0009333_abnormal_splenocyte_physiolog1.53650321
37MP0005253_abnormal_eye_physiology1.50471602
38MP0003183_abnormal_peptide_metabolism1.49874472
39MP0002064_seizures1.49844785
40MP0002234_abnormal_pharynx_morphology1.44392746
41MP0000015_abnormal_ear_pigmentation1.43691019
42MP0004134_abnormal_chest_morphology1.42745012
43MP0001486_abnormal_startle_reflex1.38369972
44MP0000685_abnormal_immune_system1.37353640
45MP0005367_renal/urinary_system_phenotyp1.36413153
46MP0000516_abnormal_urinary_system1.36413153
47MP0003635_abnormal_synaptic_transmissio1.36017490
48MP0003656_abnormal_erythrocyte_physiolo1.35586413
49MP0009745_abnormal_behavioral_response1.34260390
50MP0002572_abnormal_emotion/affect_behav1.33366268
51MP0008995_early_reproductive_senescence1.32331307
52MP0002638_abnormal_pupillary_reflex1.31465066
53MP0001188_hyperpigmentation1.31239351
54MP0002148_abnormal_hypersensitivity_rea1.31140142
55MP0001968_abnormal_touch/_nociception1.31007283
56MP0002420_abnormal_adaptive_immunity1.30532486
57MP0005171_absent_coat_pigmentation1.29724463
58MP0002723_abnormal_immune_serum1.29261340
59MP0002398_abnormal_bone_marrow1.28060478
60MP0002938_white_spotting1.28034142
61MP0002102_abnormal_ear_morphology1.27859449
62MP0001819_abnormal_immune_cell1.27672825
63MP0009046_muscle_twitch1.24749002
64MP0005551_abnormal_eye_electrophysiolog1.23426956
65MP0005645_abnormal_hypothalamus_physiol1.23139624
66MP0003890_abnormal_embryonic-extraembry1.22872072
67MP0001800_abnormal_humoral_immune1.22727876
68MP0003693_abnormal_embryo_hatching1.22258456
69MP0001764_abnormal_homeostasis1.21968588
70MP0000372_irregular_coat_pigmentation1.21815578
71MP0004270_analgesia1.21396724
72MP0002876_abnormal_thyroid_physiology1.21137921
73MP0003937_abnormal_limbs/digits/tail_de1.20116721
74MP0005000_abnormal_immune_tolerance1.19320475
75MP0002095_abnormal_skin_pigmentation1.17213810
76MP0005025_abnormal_response_to1.17175716
77MP0005187_abnormal_penis_morphology1.16711335
78MP0000778_abnormal_nervous_system1.16360918
79MP0003077_abnormal_cell_cycle1.16202189
80MP0001929_abnormal_gametogenesis1.16151971
81MP0002452_abnormal_antigen_presenting1.13788652
82MP0003786_premature_aging1.13139377
83MP0000716_abnormal_immune_system1.11816664
84MP0002734_abnormal_mechanical_nocicepti1.11663661
85MP0006276_abnormal_autonomic_nervous1.11522374
86MP0005058_abnormal_lysosome_morphology1.11369172
87MP0000465_gastrointestinal_hemorrhage1.11330786
88MP0003172_abnormal_lysosome_physiology1.10759822
89MP0003567_abnormal_fetal_cardiomyocyte1.10270320
90MP0004133_heterotaxia1.09742079
91MP0006035_abnormal_mitochondrial_morpho1.09444053
92MP0001502_abnormal_circadian_rhythm1.08894978
93MP0002063_abnormal_learning/memory/cond1.08477305
94MP0002419_abnormal_innate_immunity1.08138045
95MP0000631_abnormal_neuroendocrine_gland1.08080720
96MP0002210_abnormal_sex_determination1.07308628
97MP0004742_abnormal_vestibular_system1.05649880
98MP0001286_abnormal_eye_development1.05296603
99MP0001485_abnormal_pinna_reflex1.04441875
100MP0002067_abnormal_sensory_capabilities1.04199080
101MP0000689_abnormal_spleen_morphology1.03741696
102MP0008007_abnormal_cellular_replicative1.01715213
103MP0002163_abnormal_gland_morphology1.01027418
104MP0000049_abnormal_middle_ear1.00802560
105MP0002837_dystrophic_cardiac_calcinosis1.00173273
106MP0002233_abnormal_nose_morphology1.00140506
107MP0001984_abnormal_olfaction1.00060734
108MP0005386_behavior/neurological_phenoty0.99615984
109MP0004924_abnormal_behavior0.99615984
110MP0003119_abnormal_digestive_system0.99024811
111MP0002429_abnormal_blood_cell0.97757235
112MP0003111_abnormal_nucleus_morphology0.96433609
113MP0000653_abnormal_sex_gland0.96261456
114MP0005248_abnormal_Harderian_gland0.95856103
115MP0003315_abnormal_perineum_morphology0.95765279
116MP0003221_abnormal_cardiomyocyte_apopto0.93354581
117MP0002557_abnormal_social/conspecific_i0.93075653
118MP0003136_yellow_coat_color0.92725814
119MP0001145_abnormal_male_reproductive0.92618443
120MP0005409_darkened_coat_color0.91764500
121MP0005389_reproductive_system_phenotype0.91698669
122MP0004957_abnormal_blastocyst_morpholog0.91631063
123MP0005379_endocrine/exocrine_gland_phen0.91075626
124MP0006036_abnormal_mitochondrial_physio0.90850857
125MP0001919_abnormal_reproductive_system0.90850553
126MP0005391_vision/eye_phenotype0.90836261
127MP0001970_abnormal_pain_threshold0.90619407
128MP0003724_increased_susceptibility_to0.90027697
129MP0003698_abnormal_male_reproductive0.90010973
130MP0002229_neurodegeneration0.89838111
131MP0005084_abnormal_gallbladder_morpholo0.89685198
132MP0005387_immune_system_phenotype0.89473141
133MP0001790_abnormal_immune_system0.89473141
134MP0002090_abnormal_vision0.88916590
135MP0002735_abnormal_chemical_nociception0.88795175
136MP0002751_abnormal_autonomic_nervous0.88349497
137MP0008932_abnormal_embryonic_tissue0.87908182
138MP0000681_abnormal_thyroid_gland0.87575832
139MP0002722_abnormal_immune_system0.85556065
140MP0001963_abnormal_hearing_physiology0.85478536
141MP0005410_abnormal_fertilization0.85416497
142MP0002184_abnormal_innervation0.85178481
143MP0003121_genomic_imprinting0.84667287
144MP0005310_abnormal_salivary_gland0.84385343
145MP0000647_abnormal_sebaceous_gland0.83014695
146MP0004215_abnormal_myocardial_fiber0.82906804
147MP0002160_abnormal_reproductive_system0.81763117
148MP0003195_calcinosis0.81548398
149MP0003011_delayed_dark_adaptation0.80697756
150MP0002752_abnormal_somatic_nervous0.80643454
151MP0001119_abnormal_female_reproductive0.79530936
152MP0000427_abnormal_hair_cycle0.76762310
153MP0005195_abnormal_posterior_eye0.76633903

Predicted human phenotypes

RankGene SetZ-score
1Degeneration of anterior horn cells (HP:0002398)3.48306405
2Abnormality of the anterior horn cell (HP:0006802)3.48306405
3Hepatocellular necrosis (HP:0001404)3.42938847
43-Methylglutaconic aciduria (HP:0003535)3.39417686
5Cerebral hypomyelination (HP:0006808)3.31770204
6Mitochondrial inheritance (HP:0001427)3.31354101
7Renal Fanconi syndrome (HP:0001994)3.30816870
8Abnormality of glycolysis (HP:0004366)3.25731890
9Increased serum pyruvate (HP:0003542)3.25731890
10Abnormality of the labia minora (HP:0012880)3.21539620
11Colon cancer (HP:0003003)3.19797127
12Birth length less than 3rd percentile (HP:0003561)3.16612514
13Acute necrotizing encephalopathy (HP:0006965)3.16282262
14Increased hepatocellular lipid droplets (HP:0006565)3.06405609
15Hyperglycinemia (HP:0002154)3.02100131
16Abnormal mitochondria in muscle tissue (HP:0008316)2.94711377
17Increased CSF lactate (HP:0002490)2.84815556
18Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.82615904
19Abnormality of alanine metabolism (HP:0010916)2.82615904
20Hyperalaninemia (HP:0003348)2.82615904
21Type I transferrin isoform profile (HP:0003642)2.78481385
22Type 2 muscle fiber atrophy (HP:0003554)2.77226830
23Retinal dysplasia (HP:0007973)2.70147210
24Hepatic necrosis (HP:0002605)2.69108923
25Abnormal hair whorl (HP:0010721)2.63501615
26Elevated erythrocyte sedimentation rate (HP:0003565)2.58201364
27Tubulointerstitial nephritis (HP:0001970)2.53942762
28Hypothermia (HP:0002045)2.52987765
29Increased serum lactate (HP:0002151)2.50938012
30CNS hypomyelination (HP:0003429)2.50890487
31Aplastic anemia (HP:0001915)2.50419800
32Cerebral edema (HP:0002181)2.48612792
33Lipid accumulation in hepatocytes (HP:0006561)2.47578026
34Methylmalonic aciduria (HP:0012120)2.46798496
35Genital tract atresia (HP:0001827)2.43802880
36True hermaphroditism (HP:0010459)2.42957256
37Vaginal atresia (HP:0000148)2.42695282
38Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.41967476
39Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.41913895
40Progressive macrocephaly (HP:0004481)2.37844276
41Atrophy/Degeneration involving motor neurons (HP:0007373)2.37478104
42Leukodystrophy (HP:0002415)2.37364333
43Muscle fiber atrophy (HP:0100295)2.36928313
44Petechiae (HP:0000967)2.34677248
45Abnormal lung lobation (HP:0002101)2.34014629
46Reduced antithrombin III activity (HP:0001976)2.33963834
47IgM deficiency (HP:0002850)2.32469269
48Acute encephalopathy (HP:0006846)2.29289921
49Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.28720309
50Abnormal protein N-linked glycosylation (HP:0012347)2.28720309
51Abnormal protein glycosylation (HP:0012346)2.28720309
52Abnormal glycosylation (HP:0012345)2.28720309
53Pancreatic cysts (HP:0001737)2.27478956
54Patchy hypopigmentation of hair (HP:0011365)2.27396292
55Volvulus (HP:0002580)2.24022617
56Medial flaring of the eyebrow (HP:0010747)2.22400906
57IgG deficiency (HP:0004315)2.21858443
58Abnormality of the heme biosynthetic pathway (HP:0010472)2.21562283
59Poor suck (HP:0002033)2.19055146
60Myositis (HP:0100614)2.18313714
61Decreased testicular size (HP:0008734)2.15792204
62Abnormality of serum amino acid levels (HP:0003112)2.15681822
63Poor coordination (HP:0002370)2.13827016
64Exertional dyspnea (HP:0002875)2.13541767
65Amyotrophic lateral sclerosis (HP:0007354)2.13373765
66Septate vagina (HP:0001153)2.11895205
67Chronic otitis media (HP:0000389)2.10396997
68Septo-optic dysplasia (HP:0100842)2.08913385
69Thyroid-stimulating hormone excess (HP:0002925)2.08844134
70Optic neuritis (HP:0100653)2.08637348
71Retrobulbar optic neuritis (HP:0100654)2.08637348
72Degeneration of the lateral corticospinal tracts (HP:0002314)2.08099902
73Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.08099902
74Hepatosplenomegaly (HP:0001433)2.07779375
75Abnormality of chromosome stability (HP:0003220)2.06006369
76Increased intramyocellular lipid droplets (HP:0012240)2.05868003
77Abnormality of DNA repair (HP:0003254)2.05706727
78Abnormality of B cell number (HP:0010975)2.05172193
79B lymphocytopenia (HP:0010976)2.05172193
80Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.04666962
81Decreased activity of mitochondrial respiratory chain (HP:0008972)2.04666962
82Chromsome breakage (HP:0040012)2.04415091
83Parakeratosis (HP:0001036)2.04370040
84Pancreatic fibrosis (HP:0100732)2.03400983
85Meckel diverticulum (HP:0002245)2.02729427
86Intestinal atresia (HP:0011100)2.01466199
87Abnormality of serine family amino acid metabolism (HP:0010894)2.01102389
88Abnormality of glycine metabolism (HP:0010895)2.01102389
89White forelock (HP:0002211)2.00692987
90Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.00301024
91Hypoplasia of the capital femoral epiphysis (HP:0003090)1.99978308
92Nephrogenic diabetes insipidus (HP:0009806)1.99919128
93Medulloblastoma (HP:0002885)1.99591887
94Abnormality of the ileum (HP:0001549)1.99401125
95Abnormality of methionine metabolism (HP:0010901)1.98153458
96Lactic acidosis (HP:0003128)1.97510824
97Optic disc pallor (HP:0000543)1.96361201
98Lissencephaly (HP:0001339)1.96296331
99Aplasia/Hypoplasia of the uvula (HP:0010293)1.96186819
100Abnormality of renal resorption (HP:0011038)1.94066691
101Prolonged neonatal jaundice (HP:0006579)1.93975362
102Cortical dysplasia (HP:0002539)1.93355582
103Specific learning disability (HP:0001328)1.92716002
104Respiratory difficulties (HP:0002880)1.92503232
105Gait imbalance (HP:0002141)1.92005566
106Focal motor seizures (HP:0011153)1.91940051
107Gonadotropin excess (HP:0000837)1.91456896
108Nephronophthisis (HP:0000090)1.90350393
109Abnormality of the renal collecting system (HP:0004742)1.90170352
110Abnormality of midbrain morphology (HP:0002418)1.89859581
111Molar tooth sign on MRI (HP:0002419)1.89859581
112Methylmalonic acidemia (HP:0002912)1.89287457
113Absent rod-and cone-mediated responses on ERG (HP:0007688)1.89166879
114Congenital primary aphakia (HP:0007707)1.87827179
115Hyperinsulinemic hypoglycemia (HP:0000825)1.87723208
116Optic nerve hypoplasia (HP:0000609)1.86606248
117Neutropenia (HP:0001875)1.85913374
118Pancytopenia (HP:0001876)1.84783074
119Pendular nystagmus (HP:0012043)1.83341900
120Recurrent abscess formation (HP:0002722)1.82283032
121Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.81376242
122Poor speech (HP:0002465)1.81224626
123Broad foot (HP:0001769)1.81133266
124Postaxial hand polydactyly (HP:0001162)1.80588401
125Hypoplastic pelvis (HP:0008839)1.79252408
126Abnormality of aspartate family amino acid metabolism (HP:0010899)1.78359009
127Irregular epiphyses (HP:0010582)1.78339534
128Panhypogammaglobulinemia (HP:0003139)1.77999530
129Abnormality of the metopic suture (HP:0005556)1.77024522
130Abnormality of vitamin B metabolism (HP:0004340)1.76781606
131Oral leukoplakia (HP:0002745)1.76297831
132Abnormal number of erythroid precursors (HP:0012131)1.75559924
133Abnormality of the vitamin B12 metabolism (HP:0004341)1.75483978
134Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.75407486
135Sloping forehead (HP:0000340)1.75042924
136Duplicated collecting system (HP:0000081)1.74832656
137Chromosomal breakage induced by crosslinking agents (HP:0003221)1.74774988
138Respiratory failure (HP:0002878)1.72995719
139Purpura (HP:0000979)1.71507901
140Type II lissencephaly (HP:0007260)1.71163426
141Severe visual impairment (HP:0001141)1.71014123
142Absent epiphyses (HP:0010577)1.70963509
143Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.70963509
144Exercise intolerance (HP:0003546)1.70812758
145Postaxial foot polydactyly (HP:0001830)1.70524345
146Abolished electroretinogram (ERG) (HP:0000550)1.70084873
147Esotropia (HP:0000565)1.69840454
148Neuroendocrine neoplasm (HP:0100634)1.69660788
149Hypoplasia of the thymus (HP:0000778)1.68888006
150Large for gestational age (HP:0001520)1.68780985
151Duodenal stenosis (HP:0100867)1.68760272
152Small intestinal stenosis (HP:0012848)1.68760272
153Postnatal microcephaly (HP:0005484)1.68353028
154Neoplasm of the adrenal gland (HP:0100631)1.68045317
155Lethargy (HP:0001254)1.66956507
156Ependymoma (HP:0002888)1.66736370
157Aplasia/Hypoplasia of the tongue (HP:0010295)1.66251335
158Abnormality of the duodenum (HP:0002246)1.66117656
159Polyphagia (HP:0002591)1.64527006
160Sclerocornea (HP:0000647)1.63453794

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK163.82066508
2TNIK3.79222262
3TRIM283.29311809
4WNK33.16039648
5CDK192.68074713
6CASK2.65218233
7ACVR1B2.64535046
8MAP4K22.59227534
9BUB12.42251000
10NEK12.41980381
11TXK2.38554508
12BMPR1B2.11430165
13MAP2K72.10224104
14PRPF4B2.08978830
15NUAK12.02245967
16CCNB12.01703414
17EIF2AK32.00957069
18MAP3K41.99737517
19MUSK1.97663856
20MAP3K121.94614303
21BCKDK1.89713600
22ERBB31.87632380
23FRK1.83680192
24CDK81.78226824
25TTK1.77896561
26MKNK11.73606329
27OXSR11.70305678
28BRSK21.68518042
29EIF2AK11.68463852
30WEE11.54742057
31MAPKAPK51.48974884
32KIT1.48758568
33VRK21.48374704
34CSNK1G31.46407682
35VRK11.43916831
36TSSK61.36997106
37TEC1.35898665
38MST41.33776330
39CAMKK21.29500036
40ARAF1.28496909
41IRAK41.24247003
42BCR1.23129734
43PLK11.20532960
44SIK31.15418883
45BTK1.15354822
46EPHA31.11971343
47DAPK11.11175505
48NME21.10128193
49FES1.05693930
50PINK11.05099137
51MAP4K11.05058018
52CLK11.05005757
53ADRBK21.04749723
54CSNK1G21.03806641
55BRSK11.03552026
56STK38L1.01968764
57CSNK1A1L1.01565956
58BMPR20.99648655
59MKNK20.99244018
60SRPK10.97391622
61PLK40.96892796
62CSNK1G10.96375149
63MAPK130.95635269
64CDK30.92510809
65DYRK20.91998119
66TESK20.90737684
67TAOK20.89803109
68GRK10.88750205
69EIF2AK20.87467838
70STK390.86941761
71CSF1R0.86737962
72UHMK10.85466675
73PAK30.85268511
74CDC70.85254643
75MINK10.83174780
76SYK0.80664428
77RPS6KA40.80012755
78PKN10.79261449
79RAF10.78487634
80BRAF0.78344486
81IKBKE0.75567525
82LYN0.74910284
83PIM20.73305832
84PBK0.73280213
85TAF10.72716842
86YES10.71753215
87PRKCG0.68218886
88PASK0.68124330
89ZAP700.65005001
90ITK0.64825035
91ATM0.63063156
92DYRK30.60052814
93AURKB0.58772186
94EPHA40.58669330
95CAMK2B0.58149093
96ATR0.57355612
97FGFR20.56507787
98PDK20.55205175
99LCK0.54976870
100TGFBR10.53937427
101PRKCE0.53562507
102PLK20.53339885
103TBK10.51552052
104RPS6KA50.49778269
105NLK0.49284622
106BRD40.48982998
107CDK180.47724621
108SGK4940.46598074
109SGK2230.46598074
110CSNK2A10.45326148
111ROCK20.45201906
112CHEK10.45085282
113NTRK20.44424909
114TAOK10.44405367
115IRAK20.42745299
116CSNK2A20.42440196
117NME10.42308555
118CSNK1A10.41868690
119CDK150.41862049
120CSNK1E0.41148814
121CDK11A0.40072624
122TNK20.40066759
123MARK10.39753852
124PRKCQ0.39633372
125NEK60.37750964
126INSRR0.37314015
127STK30.36904568
128AURKA0.36228362
129MAP3K140.35383655
130ZAK0.35206677
131FLT30.34909006
132GRK70.34244230
133IRAK10.34145612
134PLK30.33698666
135CHEK20.33275708
136MAP3K50.33255036
137DYRK1A0.33149217
138CDK10.31216353
139CAMK2A0.30618496
140CDK140.30185839
141CDK60.28208663
142CSNK1D0.27496741
143CDK20.27491215
144FGFR10.26471839
145PRKACA0.25445215
146PRKDC0.25073477

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030503.51275454
2DNA replication_Homo sapiens_hsa030303.50610954
3RNA polymerase_Homo sapiens_hsa030203.08806489
4Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.03204298
5Protein export_Homo sapiens_hsa030602.83455828
6Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.58395822
7Nucleotide excision repair_Homo sapiens_hsa034202.41717273
8Propanoate metabolism_Homo sapiens_hsa006402.33931133
9Homologous recombination_Homo sapiens_hsa034402.33047092
10Oxidative phosphorylation_Homo sapiens_hsa001902.28362161
11Base excision repair_Homo sapiens_hsa034102.27331609
12Vitamin B6 metabolism_Homo sapiens_hsa007502.10707609
13Mismatch repair_Homo sapiens_hsa034302.08644966
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.08512070
15Pyrimidine metabolism_Homo sapiens_hsa002402.06221817
16Parkinsons disease_Homo sapiens_hsa050121.99805202
17Basal transcription factors_Homo sapiens_hsa030221.99008049
18Fatty acid elongation_Homo sapiens_hsa000621.96626031
19Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.96268516
20Butanoate metabolism_Homo sapiens_hsa006501.90201308
21Ribosome_Homo sapiens_hsa030101.79282350
22SNARE interactions in vesicular transport_Homo sapiens_hsa041301.78397231
23Spliceosome_Homo sapiens_hsa030401.75535800
24Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.67924908
25Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.64422606
26Primary immunodeficiency_Homo sapiens_hsa053401.61198473
27Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.57040053
28Steroid biosynthesis_Homo sapiens_hsa001001.56931029
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.55479845
30Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.49512058
31Purine metabolism_Homo sapiens_hsa002301.47063033
32RNA degradation_Homo sapiens_hsa030181.45209912
33Non-homologous end-joining_Homo sapiens_hsa034501.39158263
34Cell cycle_Homo sapiens_hsa041101.37723384
35Allograft rejection_Homo sapiens_hsa053301.37699121
36Alzheimers disease_Homo sapiens_hsa050101.36319745
37Autoimmune thyroid disease_Homo sapiens_hsa053201.35217343
38Huntingtons disease_Homo sapiens_hsa050161.33628949
39Ether lipid metabolism_Homo sapiens_hsa005651.33001772
40Pyruvate metabolism_Homo sapiens_hsa006201.32551123
41Graft-versus-host disease_Homo sapiens_hsa053321.28513403
422-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.27217510
43Fanconi anemia pathway_Homo sapiens_hsa034601.26312539
44One carbon pool by folate_Homo sapiens_hsa006701.25972448
45Selenocompound metabolism_Homo sapiens_hsa004501.25658788
46Peroxisome_Homo sapiens_hsa041461.21359720
47Regulation of autophagy_Homo sapiens_hsa041401.18435764
48RNA transport_Homo sapiens_hsa030131.07679094
49Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.04034449
50Biosynthesis of amino acids_Homo sapiens_hsa012301.03096506
51Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.01453362
52Carbon metabolism_Homo sapiens_hsa012001.01295328
53Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.98656472
54Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.98587811
55Nicotine addiction_Homo sapiens_hsa050330.97741097
56Collecting duct acid secretion_Homo sapiens_hsa049660.92742960
57Maturity onset diabetes of the young_Homo sapiens_hsa049500.91537563
58Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.91481456
59Rheumatoid arthritis_Homo sapiens_hsa053230.90625789
60Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.90224146
61Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.89678363
62Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.89436528
63Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.86757585
64Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.85912305
65Intestinal immune network for IgA production_Homo sapiens_hsa046720.83574901
66Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.83035669
67Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.82471264
68Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.82454516
69beta-Alanine metabolism_Homo sapiens_hsa004100.82316041
70Other glycan degradation_Homo sapiens_hsa005110.82234366
71Hematopoietic cell lineage_Homo sapiens_hsa046400.80362057
72Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.80216817
73Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.76481333
74Caffeine metabolism_Homo sapiens_hsa002320.76020377
75Fatty acid metabolism_Homo sapiens_hsa012120.75732822
76N-Glycan biosynthesis_Homo sapiens_hsa005100.74990301
77Epstein-Barr virus infection_Homo sapiens_hsa051690.73668523
78Shigellosis_Homo sapiens_hsa051310.72301722
79Taste transduction_Homo sapiens_hsa047420.70194837
80Serotonergic synapse_Homo sapiens_hsa047260.69900122
81Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.68556992
82Measles_Homo sapiens_hsa051620.67536296
83Herpes simplex infection_Homo sapiens_hsa051680.67294222
84Arachidonic acid metabolism_Homo sapiens_hsa005900.65768380
85Pentose and glucuronate interconversions_Homo sapiens_hsa000400.64964382
86Type I diabetes mellitus_Homo sapiens_hsa049400.64687488
87Sphingolipid metabolism_Homo sapiens_hsa006000.64377857
88Tryptophan metabolism_Homo sapiens_hsa003800.64199720
89mRNA surveillance pathway_Homo sapiens_hsa030150.62767502
90Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.62127000
91Antigen processing and presentation_Homo sapiens_hsa046120.61678351
92Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.59832379
93Glutamatergic synapse_Homo sapiens_hsa047240.58091486
94Folate biosynthesis_Homo sapiens_hsa007900.57723533
95Vibrio cholerae infection_Homo sapiens_hsa051100.56805797
96p53 signaling pathway_Homo sapiens_hsa041150.56592885
97Arginine and proline metabolism_Homo sapiens_hsa003300.56327342
98Morphine addiction_Homo sapiens_hsa050320.56327001
99Primary bile acid biosynthesis_Homo sapiens_hsa001200.56059090
100Fatty acid degradation_Homo sapiens_hsa000710.55189572
101Phototransduction_Homo sapiens_hsa047440.53252044
102RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.52767159
103Metabolic pathways_Homo sapiens_hsa011000.52100497
104Olfactory transduction_Homo sapiens_hsa047400.51312787
105Asthma_Homo sapiens_hsa053100.51156257
106GABAergic synapse_Homo sapiens_hsa047270.50086333
107Sulfur metabolism_Homo sapiens_hsa009200.49819940
108Phagosome_Homo sapiens_hsa041450.48071480
109Retinol metabolism_Homo sapiens_hsa008300.46300355
110Alcoholism_Homo sapiens_hsa050340.44525657
111Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.44489758
112Glutathione metabolism_Homo sapiens_hsa004800.44179596
113Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.44134998
114Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.44092623
115Synaptic vesicle cycle_Homo sapiens_hsa047210.44041100
116Cardiac muscle contraction_Homo sapiens_hsa042600.43488159
117NF-kappa B signaling pathway_Homo sapiens_hsa040640.41769159
118T cell receptor signaling pathway_Homo sapiens_hsa046600.39808778
119Linoleic acid metabolism_Homo sapiens_hsa005910.39482377
120Circadian rhythm_Homo sapiens_hsa047100.38937456
121Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.37513705
122Legionellosis_Homo sapiens_hsa051340.37500676
123Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37391095
124Hedgehog signaling pathway_Homo sapiens_hsa043400.37227703
125Cysteine and methionine metabolism_Homo sapiens_hsa002700.37202677
126Circadian entrainment_Homo sapiens_hsa047130.36489642
127Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.36360457
128Malaria_Homo sapiens_hsa051440.35869381
129Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.34449501
130Pentose phosphate pathway_Homo sapiens_hsa000300.33992798
131Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.33166672
132Dopaminergic synapse_Homo sapiens_hsa047280.33044338
133Nitrogen metabolism_Homo sapiens_hsa009100.33035037
134Tyrosine metabolism_Homo sapiens_hsa003500.31087048
135Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.29500941
136Systemic lupus erythematosus_Homo sapiens_hsa053220.27596303
137Phenylalanine metabolism_Homo sapiens_hsa003600.27090106
138Lysine degradation_Homo sapiens_hsa003100.26597624
139Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.26339705
140Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.23690148
141Sulfur relay system_Homo sapiens_hsa041220.23539631
142Ovarian steroidogenesis_Homo sapiens_hsa049130.23175629
143Oocyte meiosis_Homo sapiens_hsa041140.22617248

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »