TAF9P3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of meiosis I (GO:0060631)9.52461828
2regulation of Golgi to plasma membrane protein transport (GO:0042996)9.31670423
3monoubiquitinated protein deubiquitination (GO:0035520)7.15699345
4positive regulation of G-protein coupled receptor protein signaling pathway (GO:0045745)6.43129427
5negative regulation of meiosis (GO:0045835)6.04765944
6somatic diversification of immune receptors via somatic mutation (GO:0002566)5.30102454
7somatic hypermutation of immunoglobulin genes (GO:0016446)5.30102454
8embryonic viscerocranium morphogenesis (GO:0048703)5.15022481
9glucosamine-containing compound catabolic process (GO:1901072)4.98412326
10response to xenobiotic stimulus (GO:0009410)4.94248356
11segment specification (GO:0007379)4.86962249
12spermatid nucleus differentiation (GO:0007289)4.79275882
13regulation of cellular senescence (GO:2000772)4.67273238
14fusion of sperm to egg plasma membrane (GO:0007342)4.49101945
15forebrain morphogenesis (GO:0048853)4.48146357
16embryonic heart tube development (GO:0035050)4.46855773
17negative regulation of meiotic cell cycle (GO:0051447)4.44485858
18response to nitrosative stress (GO:0051409)4.36317625
19establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.09140680
20mitochondrion transport along microtubule (GO:0047497)4.09140680
21DNA deamination (GO:0045006)3.93111281
22regulation of platelet aggregation (GO:0090330)3.85063478
23positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.71196924
24mitotic sister chromatid cohesion (GO:0007064)3.68712819
25mannosylation (GO:0097502)3.65506420
26regulation of rhodopsin mediated signaling pathway (GO:0022400)3.64951516
27oogenesis (GO:0048477)3.64172278
28protein targeting to Golgi (GO:0000042)3.51531801
29thyroid gland development (GO:0030878)3.50962969
30interkinetic nuclear migration (GO:0022027)3.50412288
31retrograde transport, vesicle recycling within Golgi (GO:0000301)3.49133316
32negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)3.47346810
33neural tube formation (GO:0001841)3.43902150
34establishment of mitochondrion localization (GO:0051654)3.39884302
35regulation of acrosome reaction (GO:0060046)3.39581934
36positive regulation of interleukin-1 beta secretion (GO:0050718)3.34549708
37positive regulation of guanylate cyclase activity (GO:0031284)3.32834322
38protein-cofactor linkage (GO:0018065)3.32389143
39rhodopsin mediated signaling pathway (GO:0016056)3.30344367
40protein K63-linked deubiquitination (GO:0070536)3.30188375
41positive regulation of interleukin-17 production (GO:0032740)3.29208402
42establishment of protein localization to Golgi (GO:0072600)3.29054443
43plasma membrane fusion (GO:0045026)3.27276359
44phosphatidylinositol acyl-chain remodeling (GO:0036149)3.26707691
45cysteine metabolic process (GO:0006534)3.23900423
46amino sugar catabolic process (GO:0046348)3.22676265
47negative regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045736)3.21368228
48poly(A)+ mRNA export from nucleus (GO:0016973)3.20260227
49positive regulation of interleukin-4 production (GO:0032753)3.17489344
50mucosal-associated lymphoid tissue development (GO:0048537)3.17364244
51Peyers patch development (GO:0048541)3.17364244
52embryonic camera-type eye development (GO:0031076)3.17301721
53ribosomal small subunit assembly (GO:0000028)3.16505931
54spinal cord association neuron differentiation (GO:0021527)3.16124588
55regulation of helicase activity (GO:0051095)3.15787830
56sister chromatid cohesion (GO:0007062)3.15269491
57positive regulation of interleukin-1 secretion (GO:0050716)3.13018386
58histone deubiquitination (GO:0016578)3.11551399
59regulation of axon regeneration (GO:0048679)3.07536723
60regulation of neuron projection regeneration (GO:0070570)3.07536723
61hepatocyte differentiation (GO:0070365)3.06825028
62ribosomal large subunit biogenesis (GO:0042273)3.05794613
63definitive hemopoiesis (GO:0060216)3.04670311
64regulation of cell aging (GO:0090342)3.00633610
65regulation of interleukin-2 biosynthetic process (GO:0045076)2.99330062
66regulation of guanylate cyclase activity (GO:0031282)2.95311287
67fertilization (GO:0009566)2.93239469
68thrombin receptor signaling pathway (GO:0070493)2.92743208
69regulation of interleukin-1 beta secretion (GO:0050706)2.92531657
70C4-dicarboxylate transport (GO:0015740)2.91450763
71endothelium development (GO:0003158)2.90955416
72cytidine deamination (GO:0009972)2.89763152
73cytidine metabolic process (GO:0046087)2.89763152
74cytidine catabolic process (GO:0006216)2.89763152
75regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.88542271
76positive regulation of vasculogenesis (GO:2001214)2.87950798
77preassembly of GPI anchor in ER membrane (GO:0016254)2.81956252
78regulation of erythrocyte differentiation (GO:0045646)2.79417398
79nitric oxide metabolic process (GO:0046209)2.79274895
80GPI anchor biosynthetic process (GO:0006506)2.77590560
81regulation of mitochondrial translation (GO:0070129)2.76603533
82peptidyl-histidine modification (GO:0018202)2.70140668
83sperm-egg recognition (GO:0035036)2.69237750
84positive regulation of cAMP-mediated signaling (GO:0043950)2.68870266
85reciprocal meiotic recombination (GO:0007131)2.68718528
86reciprocal DNA recombination (GO:0035825)2.68718528
87attachment of spindle microtubules to kinetochore (GO:0008608)2.68295215
88apical protein localization (GO:0045176)2.67008375
89hematopoietic stem cell differentiation (GO:0060218)2.66812564
90positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.66459892
91determination of adult lifespan (GO:0008340)2.65426258
92positive regulation of myoblast differentiation (GO:0045663)2.65343819
93GPI anchor metabolic process (GO:0006505)2.65274576
94mature B cell differentiation (GO:0002335)2.65172359
95protein localization to Golgi apparatus (GO:0034067)2.64771785
96positive regulation of interleukin-1 beta production (GO:0032731)2.63551698
97mature B cell differentiation involved in immune response (GO:0002313)2.61468590
98protein targeting to lysosome (GO:0006622)2.60401871
99establishment of protein localization to vacuole (GO:0072666)2.60401871
100protein targeting to vacuole (GO:0006623)2.60401871

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IGF1R_20145208_ChIP-Seq_DFB_Human5.96733646
2BP1_19119308_ChIP-ChIP_Hs578T_Human4.93704335
3VDR_22108803_ChIP-Seq_LS180_Human4.50422619
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse4.45276720
5ZNF274_21170338_ChIP-Seq_K562_Hela4.02476959
6SCL_19346495_ChIP-Seq_HPC-7_Human3.65861897
7TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.48953911
8ELF1_17652178_ChIP-ChIP_JURKAT_Human3.32197813
9SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.78484349
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.48617506
11MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.48391181
12STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.35834480
13FOXP3_21729870_ChIP-Seq_TREG_Human2.32908911
14RBPJ_22232070_ChIP-Seq_NCS_Mouse2.21486634
15EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human2.18504597
16IRF1_19129219_ChIP-ChIP_H3396_Human2.17252866
17HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.14298090
18FOXA1_21572438_ChIP-Seq_LNCaP_Human2.14114818
19PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.09982092
20POU3F2_20337985_ChIP-ChIP_501MEL_Human2.00986290
21HTT_18923047_ChIP-ChIP_STHdh_Human1.99936709
22PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.99233823
23IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.98733877
24POU5F1_16153702_ChIP-ChIP_HESCs_Human1.94599970
25HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.83025196
26PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.79714921
27TP63_19390658_ChIP-ChIP_HaCaT_Human1.67984836
28ELK1_19687146_ChIP-ChIP_HELA_Human1.64322162
29IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.56531850
30TP53_22573176_ChIP-Seq_HFKS_Human1.56454931
31TAF15_26573619_Chip-Seq_HEK293_Human1.56077808
32ER_23166858_ChIP-Seq_MCF-7_Human1.52950305
33LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.52141440
34CTBP1_25329375_ChIP-Seq_LNCAP_Human1.43259817
35GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.40360920
36BMI1_23680149_ChIP-Seq_NPCS_Mouse1.39017790
37GATA3_21878914_ChIP-Seq_MCF-7_Human1.37139066
38GATA3_26560356_Chip-Seq_TH2_Human1.36734294
39NRF2_20460467_ChIP-Seq_MEFs_Mouse1.36550955
40NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.36550955
41GABP_17652178_ChIP-ChIP_JURKAT_Human1.35909325
42VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.35148042
43KLF5_20875108_ChIP-Seq_MESCs_Mouse1.29443977
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.28113371
45TAL1_26923725_Chip-Seq_HPCs_Mouse1.25955793
46SMRT_27268052_Chip-Seq_Bcells_Human1.25247780
47PIAS1_25552417_ChIP-Seq_VCAP_Human1.23416207
48RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.21935428
49RUNX2_22187159_ChIP-Seq_PCA_Human1.21104681
50CDX2_22108803_ChIP-Seq_LS180_Human1.20704095
51VDR_23849224_ChIP-Seq_CD4+_Human1.19515827
52FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.18262606
53FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.17543570
54E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.16497428
55KAP1_22055183_ChIP-Seq_ESCs_Mouse1.16272120
56EZH2_22144423_ChIP-Seq_EOC_Human1.15997548
57MYC_18940864_ChIP-ChIP_HL60_Human1.15208178
58FOXA1_27270436_Chip-Seq_PROSTATE_Human1.14700291
59FOXA1_25329375_ChIP-Seq_VCAP_Human1.14700291
60RUNX_20019798_ChIP-Seq_JUKART_Human1.13916882
61EST1_17652178_ChIP-ChIP_JURKAT_Human1.12599634
62PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.11090061
63MYB_26560356_Chip-Seq_TH2_Human1.09188998
64PRDM14_20953172_ChIP-Seq_ESCs_Human1.09138295
65TAF2_19829295_ChIP-Seq_ESCs_Human1.08697493
66MYC_19829295_ChIP-Seq_ESCs_Human1.08506235
67ETS1_20019798_ChIP-Seq_JURKAT_Human1.07403371
68TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07165483
69ZFP57_27257070_Chip-Seq_ESCs_Mouse1.05348864
70MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.00930283
71MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.00706546
72TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.99955511
73FOXH1_21741376_ChIP-Seq_ESCs_Human0.98545884
74NANOG_20526341_ChIP-Seq_ESCs_Human0.97222160
75NANOG_16153702_ChIP-ChIP_HESCs_Human0.96249705
76SOX2_19829295_ChIP-Seq_ESCs_Human0.95537657
77NANOG_19829295_ChIP-Seq_ESCs_Human0.95537657
78P300_19829295_ChIP-Seq_ESCs_Human0.94912819
79CBX2_27304074_Chip-Seq_ESCs_Mouse0.92065544
80JUN_21703547_ChIP-Seq_K562_Human0.91225275
81UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91082356
82MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.90371770
83GATA3_26560356_Chip-Seq_TH1_Human0.87364023
84SALL1_21062744_ChIP-ChIP_HESCs_Human0.86679826
85VDR_24787735_ChIP-Seq_THP-1_Human0.86438865
86RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.85292604
87SOX2_16153702_ChIP-ChIP_HESCs_Human0.82039701
88GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81441429
89TCF4_23295773_ChIP-Seq_U87_Human0.81068295
90ESET_19884257_ChIP-Seq_ESCs_Mouse0.80831298
91AR_20517297_ChIP-Seq_VCAP_Human0.80379387
92CTBP2_25329375_ChIP-Seq_LNCAP_Human0.80360876
93GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.80313283
94ERG_20517297_ChIP-Seq_VCAP_Human0.79873273
95AR_21909140_ChIP-Seq_LNCAP_Human0.78698411
96TP53_16413492_ChIP-PET_HCT116_Human0.78470643
97EZH2_27294783_Chip-Seq_NPCs_Mouse0.78463427
98LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.76176214
99GBX2_23144817_ChIP-Seq_PC3_Human0.75747604
100GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75671049

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002102_abnormal_ear_morphology9.43532068
2MP0005670_abnormal_white_adipose4.55802768
3MP0005379_endocrine/exocrine_gland_phen3.89696722
4MP0003183_abnormal_peptide_metabolism3.78852398
5MP0002653_abnormal_ependyma_morphology3.12557085
6MP0006292_abnormal_olfactory_placode3.03487044
7MP0005666_abnormal_adipose_tissue2.37664005
8MP0003878_abnormal_ear_physiology2.19221935
9MP0005377_hearing/vestibular/ear_phenot2.19221935
10MP0002234_abnormal_pharynx_morphology2.04920108
11MP0000681_abnormal_thyroid_gland1.99151410
12MP0005645_abnormal_hypothalamus_physiol1.94485459
13MP0000678_abnormal_parathyroid_gland1.92711758
14MP0003567_abnormal_fetal_cardiomyocyte1.91459749
15MP0001529_abnormal_vocalization1.90732783
16MP0000383_abnormal_hair_follicle1.90539827
17MP0010352_gastrointestinal_tract_polyps1.85415436
18MP0001661_extended_life_span1.82466771
19MP0004147_increased_porphyrin_level1.74480719
20MP0002132_abnormal_respiratory_system1.68041434
21MP0002928_abnormal_bile_duct1.68013261
22MP0004215_abnormal_myocardial_fiber1.64817035
23MP0005409_darkened_coat_color1.60847525
24MP0008058_abnormal_DNA_repair1.60571767
25MP0005084_abnormal_gallbladder_morpholo1.56709119
26MP0001270_distended_abdomen1.51013090
27MP0004130_abnormal_muscle_cell1.46764888
28MP0000569_abnormal_digit_pigmentation1.46588158
29MP0006072_abnormal_retinal_apoptosis1.46256125
30MP0003123_paternal_imprinting1.42437757
31MP0004185_abnormal_adipocyte_glucose1.41672396
32MP0008875_abnormal_xenobiotic_pharmacok1.41537791
33MP0008961_abnormal_basal_metabolism1.39825175
34MP0001664_abnormal_digestion1.37574711
35MP0005253_abnormal_eye_physiology1.29768577
36MP0005464_abnormal_platelet_physiology1.29350557
37MP0000613_abnormal_salivary_gland1.26078125
38MP0002163_abnormal_gland_morphology1.19093235
39MP0004134_abnormal_chest_morphology1.17719768
40MP0003195_calcinosis1.16260198
41MP0003011_delayed_dark_adaptation1.14724944
42MP0001502_abnormal_circadian_rhythm1.14086990
43MP0000015_abnormal_ear_pigmentation1.09834630
44MP0002837_dystrophic_cardiac_calcinosis1.08236608
45MP0001348_abnormal_lacrimal_gland1.06423771
46MP0001293_anophthalmia1.04957464
47MP0003111_abnormal_nucleus_morphology1.04374462
48MP0002127_abnormal_cardiovascular_syste1.02384218
49MP0004808_abnormal_hematopoietic_stem0.98926426
50MP0008872_abnormal_physiological_respon0.98566228
51MP0001486_abnormal_startle_reflex0.97037385
52MP0005551_abnormal_eye_electrophysiolog0.96890233
53MP0005647_abnormal_sex_gland0.96831230
54MP0003763_abnormal_thymus_physiology0.95616578
55MP0004264_abnormal_extraembryonic_tissu0.94590231
56MP0005397_hematopoietic_system_phenotyp0.94344732
57MP0001545_abnormal_hematopoietic_system0.94344732
58MP0001324_abnormal_eye_pigmentation0.93097514
59MP0002249_abnormal_larynx_morphology0.92405463
60MP0009333_abnormal_splenocyte_physiolog0.91019587
61MP0006276_abnormal_autonomic_nervous0.88353700
62MP0006054_spinal_hemorrhage0.88285872
63MP0001879_abnormal_lymphatic_vessel0.86827275
64MP0001919_abnormal_reproductive_system0.86693873
65MP0010678_abnormal_skin_adnexa0.86403826
66MP0003656_abnormal_erythrocyte_physiolo0.84917356
67MP0003632_abnormal_nervous_system0.83642618
68MP0000049_abnormal_middle_ear0.81801648
69MP0001764_abnormal_homeostasis0.81019170
70MP0000762_abnormal_tongue_morphology0.77683449
71MP0008789_abnormal_olfactory_epithelium0.77378088
72MP0003943_abnormal_hepatobiliary_system0.77318853
73MP0003880_abnormal_central_pattern0.76246796
74MP0000778_abnormal_nervous_system0.75441277
75MP0001727_abnormal_embryo_implantation0.72835486
76MP0005391_vision/eye_phenotype0.71145649
77MP0000566_synostosis0.68468117
78MP0003698_abnormal_male_reproductive0.67710779
79MP0000653_abnormal_sex_gland0.64625149
80MP0002095_abnormal_skin_pigmentation0.64330908
81MP0003935_abnormal_craniofacial_develop0.63239513
82MP0000631_abnormal_neuroendocrine_gland0.61725686
83MP0000490_abnormal_crypts_of0.58433028
84MP0002210_abnormal_sex_determination0.58418726
85MP0000427_abnormal_hair_cycle0.58415983
86MP0001929_abnormal_gametogenesis0.57745286
87MP0002932_abnormal_joint_morphology0.57739294
88MP0003252_abnormal_bile_duct0.57058565
89MP0005075_abnormal_melanosome_morpholog0.56192422
90MP0001145_abnormal_male_reproductive0.56076814
91MP0005389_reproductive_system_phenotype0.55942774
92MP0005375_adipose_tissue_phenotype0.53885599
93MP0001119_abnormal_female_reproductive0.53811105
94MP0004484_altered_response_of0.53749912
95MP0002177_abnormal_outer_ear0.53458278
96MP0003300_gastrointestinal_ulcer0.51603387
97MP0002114_abnormal_axial_skeleton0.50771952
98MP0000689_abnormal_spleen_morphology0.50690436
99MP0002638_abnormal_pupillary_reflex0.50116866
100MP0004043_abnormal_pH_regulation0.49720276

Predicted human phenotypes

RankGene SetZ-score
1Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.67323363
2Degeneration of the lateral corticospinal tracts (HP:0002314)4.67323363
3Abnormality of the 4th metacarpal (HP:0010012)4.29808348
4Central scotoma (HP:0000603)4.14592874
5Amyotrophic lateral sclerosis (HP:0007354)3.86355859
6Stomach cancer (HP:0012126)3.85658120
7Mixed hearing impairment (HP:0000410)3.81806594
8Absent rod-and cone-mediated responses on ERG (HP:0007688)3.78485453
9Abnormality of the corticospinal tract (HP:0002492)3.75761525
10Papillary thyroid carcinoma (HP:0002895)3.67581976
11Rhabdomyosarcoma (HP:0002859)3.64490675
12Colon cancer (HP:0003003)3.55773264
13Abnormality of the parathyroid morphology (HP:0011766)3.50038328
14Basal cell carcinoma (HP:0002671)3.44004955
15Decreased central vision (HP:0007663)3.39273221
16Biliary tract neoplasm (HP:0100574)3.35994557
17Nonimmune hydrops fetalis (HP:0001790)3.30804075
18Carpal bone hypoplasia (HP:0001498)3.28613026
19Ependymoma (HP:0002888)3.12304888
20Abnormality of macular pigmentation (HP:0008002)3.05062431
21Rimmed vacuoles (HP:0003805)3.01397589
22Neoplasm of the rectum (HP:0100743)3.01340205
23Neoplasm of striated muscle (HP:0009728)2.93496022
24Stenosis of the external auditory canal (HP:0000402)2.92191800
25Medulloblastoma (HP:0002885)2.79626513
26Anterior segment dysgenesis (HP:0007700)2.64276548
27Agnosia (HP:0010524)2.63449537
28Abnormality of the prostate (HP:0008775)2.62164622
29Thrombocytosis (HP:0001894)2.58045270
30Scotoma (HP:0000575)2.55746720
31Neoplasm of the small intestine (HP:0100833)2.46832905
32Nephroblastoma (Wilms tumor) (HP:0002667)2.43247091
33Abnormal rod and cone electroretinograms (HP:0008323)2.41026209
34Attenuation of retinal blood vessels (HP:0007843)2.40346989
35Chronic obstructive pulmonary disease (HP:0006510)2.37878509
36Obstructive lung disease (HP:0006536)2.37878509
37Retinal dysplasia (HP:0007973)2.35808380
38Dyskinesia (HP:0100660)2.34697878
39Embryonal renal neoplasm (HP:0011794)2.30946670
40Impaired vibration sensation in the lower limbs (HP:0002166)2.26121148
41Neoplasm of the colon (HP:0100273)2.22676973
42Erythema (HP:0010783)2.20044689
43Astrocytoma (HP:0009592)2.19637627
44Abnormality of the astrocytes (HP:0100707)2.19637627
45Deformed sella turcica (HP:0002681)2.15478947
46Abnormality of the nasal septum (HP:0000419)2.15348907
47Neoplasm of the thyroid gland (HP:0100031)2.13392712
48Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.13387576
49Agitation (HP:0000713)2.08888320
50Neoplasm of the tracheobronchial system (HP:0100552)2.08859700
51Athetosis (HP:0002305)2.07694260
52Glioma (HP:0009733)2.07014819
53Rectal fistula (HP:0100590)2.05284810
54Rectovaginal fistula (HP:0000143)2.05284810
55Renal cell carcinoma (HP:0005584)2.04898769
56Type I transferrin isoform profile (HP:0003642)2.04365388
57Seborrheic dermatitis (HP:0001051)2.02686032
58Adenoma sebaceum (HP:0009720)2.02043040
59Angiofibromas (HP:0010615)2.02043040
60Agammaglobulinemia (HP:0004432)2.01915739
61Abolished electroretinogram (ERG) (HP:0000550)2.01814512
62Megalencephaly (HP:0001355)1.99345354
63Alveolar cell carcinoma (HP:0006519)1.98994005
64Constricted visual fields (HP:0001133)1.98082753
65Neoplasm of the pancreas (HP:0002894)1.97938116
66Abnormality of the lower motor neuron (HP:0002366)1.97279690
67Molar tooth sign on MRI (HP:0002419)1.94748410
68Abnormality of midbrain morphology (HP:0002418)1.94748410
69Embryonal neoplasm (HP:0002898)1.94082225
70Prostate neoplasm (HP:0100787)1.91713057
71Back pain (HP:0003418)1.89147066
72Panhypogammaglobulinemia (HP:0003139)1.88401202
73Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.85477752
74Decreased activity of mitochondrial respiratory chain (HP:0008972)1.85477752
75Abnormal biliary tract morphology (HP:0012440)1.84581779
76Broad palm (HP:0001169)1.83886807
77Nephronophthisis (HP:0000090)1.83577162
78Abnormal hemoglobin (HP:0011902)1.82866217
79Poor eye contact (HP:0000817)1.81826937
80Neoplasm of the oral cavity (HP:0100649)1.80727690
81Hypercortisolism (HP:0001578)1.79972357
82Type II lissencephaly (HP:0007260)1.75057125
83Aplasia/Hypoplasia of the sacrum (HP:0008517)1.74496511
84Tented upper lip vermilion (HP:0010804)1.72957550
85Neonatal respiratory distress (HP:0002643)1.72263769
86Reticulocytopenia (HP:0001896)1.71691711
87Gastrointestinal inflammation (HP:0004386)1.71370984
88Thickened calvaria (HP:0002684)1.70176231
89Atrophy/Degeneration involving motor neurons (HP:0007373)1.69525626
90Severe muscular hypotonia (HP:0006829)1.68392120
91Volvulus (HP:0002580)1.67775083
92Thyroid carcinoma (HP:0002890)1.66263284
93Polydipsia (HP:0001959)1.65741897
94Abnormal drinking behavior (HP:0030082)1.65741897
95Breast carcinoma (HP:0003002)1.65348919
96Abnormality of B cell number (HP:0010975)1.63146684
97Encephalitis (HP:0002383)1.62263310
98Aplasia/Hypoplasia of the thymus (HP:0010515)1.62064933
99Amaurosis fugax (HP:0100576)1.61219373
100Microvesicular hepatic steatosis (HP:0001414)1.60204283

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NUAK16.85084250
2PRKG24.49461351
3LATS14.38127509
4MAP2K33.41479095
5MAP3K63.38142072
6TXK2.54535806
7NME22.54519249
8JAK32.30782844
9BRD42.26298278
10PLK42.10016459
11PINK12.05130532
12MAP2K41.98749679
13SMG11.98324223
14PRKCQ1.97992734
15STK161.88719603
16PBK1.85443136
17MAP4K11.83672940
18STK241.82301984
19ACVR1B1.79085329
20MAP3K71.70281161
21STK31.67679468
22TNK21.55196805
23PIK3CA1.50102281
24MAP2K61.49161348
25DMPK1.46563862
26CDK31.40070289
27CDK191.37607264
28RAF11.32918476
29PIK3CG1.32679267
30MAPK71.26973079
31INSRR1.21916382
32NEK21.20162579
33ICK1.16873135
34MATK1.12403736
35WNK31.08926793
36MAP3K51.07848611
37SYK1.04804897
38CDK70.98687316
39ADRBK20.94329117
40STK110.87526178
41ZAK0.84196628
42LCK0.71725678
43TAF10.70750935
44STK380.70616390
45BUB10.70306042
46TBK10.68809610
47STK38L0.66378782
48MAPKAPK30.64245675
49SCYL20.60446890
50PRPF4B0.59178742
51VRK20.58741239
52KDR0.57208654
53RET0.57026235
54NEK10.54037477
55ZAP700.53687656
56CCNB10.53144848
57EPHA40.52917850
58PDGFRB0.52862209
59CAMKK10.48619533
60MAP3K40.46757074
61MINK10.45531005
62EGFR0.45505862
63CLK10.43734690
64ILK0.43028739
65PLK10.42956851
66IKBKB0.41258543
67ADRBK10.39837532
68FYN0.39747195
69BTK0.38606026
70PAK20.38032686
71UHMK10.37843673
72RPS6KB20.36637284
73CDK80.36031923
74ERBB30.34276577
75PRKCD0.33927442
76PRKG10.32028679
77IKBKE0.31982274
78CSK0.31557078
79PRKCE0.31555098
80PRKCA0.29704091
81PRKACA0.29398294
82MAP3K20.27446462
83MAP4K20.26819831
84ITK0.25690403
85TAOK30.24970551
86CSNK1G10.24849075
87GRK10.23833776
88MELK0.23272560
89TEC0.22915861
90CSNK1G30.22396262
91AKT20.22326154
92CAMK2D0.21809354
93PRKACG0.20036926
94AURKB0.19784546
95PAK60.19082981
96VRK10.19018662
97PRKCG0.18521585
98CAMKK20.17049147
99CAMK10.17038155
100PIM10.16320923

Predicted pathways (KEGG)

RankGene SetZ-score
1Long-term depression_Homo sapiens_hsa047302.72847094
2Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.70849066
3Phototransduction_Homo sapiens_hsa047442.67779596
4NOD-like receptor signaling pathway_Homo sapiens_hsa046212.51655763
5Platelet activation_Homo sapiens_hsa046112.40820171
6Mismatch repair_Homo sapiens_hsa034302.29190294
7Ribosome_Homo sapiens_hsa030102.25731026
8Regulation of lipolysis in adipocytes_Homo sapiens_hsa049232.15217901
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.14308391
10Serotonergic synapse_Homo sapiens_hsa047262.06944518
11Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.94304712
12Renin secretion_Homo sapiens_hsa049241.90333837
13Olfactory transduction_Homo sapiens_hsa047401.86373999
14RNA polymerase_Homo sapiens_hsa030201.84730592
15Linoleic acid metabolism_Homo sapiens_hsa005911.77849551
16Propanoate metabolism_Homo sapiens_hsa006401.75061039
17Salivary secretion_Homo sapiens_hsa049701.74816176
18Ether lipid metabolism_Homo sapiens_hsa005651.72831612
19Taste transduction_Homo sapiens_hsa047421.69002119
20Primary immunodeficiency_Homo sapiens_hsa053401.57415699
21Fanconi anemia pathway_Homo sapiens_hsa034601.48082074
22alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.38888920
23Sulfur metabolism_Homo sapiens_hsa009201.38841808
24Intestinal immune network for IgA production_Homo sapiens_hsa046721.33649822
25T cell receptor signaling pathway_Homo sapiens_hsa046601.30847000
26Circadian entrainment_Homo sapiens_hsa047131.30416677
27Pyrimidine metabolism_Homo sapiens_hsa002401.27891061
28Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.26886220
29Lysosome_Homo sapiens_hsa041421.19071178
30Cysteine and methionine metabolism_Homo sapiens_hsa002701.17540928
31Steroid hormone biosynthesis_Homo sapiens_hsa001401.16956411
32Glycosaminoglycan degradation_Homo sapiens_hsa005311.08262098
33Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.07939628
34Asthma_Homo sapiens_hsa053101.06837233
35Sphingolipid signaling pathway_Homo sapiens_hsa040711.06197780
36SNARE interactions in vesicular transport_Homo sapiens_hsa041301.06184762
37Basal transcription factors_Homo sapiens_hsa030221.03203841
38Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.02800260
39Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.01769113
40Ovarian steroidogenesis_Homo sapiens_hsa049131.00774860
41RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.00379059
42Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.00238760
43Arachidonic acid metabolism_Homo sapiens_hsa005900.95780359
44Autoimmune thyroid disease_Homo sapiens_hsa053200.95301587
45Base excision repair_Homo sapiens_hsa034100.94612781
46Glycerophospholipid metabolism_Homo sapiens_hsa005640.91780970
47Vascular smooth muscle contraction_Homo sapiens_hsa042700.90717982
48Dopaminergic synapse_Homo sapiens_hsa047280.90200147
49Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.90090913
50Pentose phosphate pathway_Homo sapiens_hsa000300.85279659
51Purine metabolism_Homo sapiens_hsa002300.85127580
52Oxytocin signaling pathway_Homo sapiens_hsa049210.83495641
53Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.83102465
54Chemical carcinogenesis_Homo sapiens_hsa052040.82908606
55Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.80712008
56Leishmaniasis_Homo sapiens_hsa051400.80317777
57Carbohydrate digestion and absorption_Homo sapiens_hsa049730.78758898
58Retinol metabolism_Homo sapiens_hsa008300.78352271
59Morphine addiction_Homo sapiens_hsa050320.77920828
60Glutamatergic synapse_Homo sapiens_hsa047240.76427596
61Melanoma_Homo sapiens_hsa052180.75981557
62Pentose and glucuronate interconversions_Homo sapiens_hsa000400.75215566
63Primary bile acid biosynthesis_Homo sapiens_hsa001200.74591881
64Transcriptional misregulation in cancer_Homo sapiens_hsa052020.72190396
65Pyruvate metabolism_Homo sapiens_hsa006200.71520656
66Measles_Homo sapiens_hsa051620.69279820
67Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.68829748
68Epstein-Barr virus infection_Homo sapiens_hsa051690.68733059
69Glycerolipid metabolism_Homo sapiens_hsa005610.68454517
70Colorectal cancer_Homo sapiens_hsa052100.66650126
71Sulfur relay system_Homo sapiens_hsa041220.66397027
72Graft-versus-host disease_Homo sapiens_hsa053320.65262745
73Hematopoietic cell lineage_Homo sapiens_hsa046400.63211485
74p53 signaling pathway_Homo sapiens_hsa041150.63185162
75beta-Alanine metabolism_Homo sapiens_hsa004100.62409353
76Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.61367142
77Non-homologous end-joining_Homo sapiens_hsa034500.61283155
78Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.61157307
79RNA degradation_Homo sapiens_hsa030180.60229695
80Allograft rejection_Homo sapiens_hsa053300.59820508
81Starch and sucrose metabolism_Homo sapiens_hsa005000.59720375
82cGMP-PKG signaling pathway_Homo sapiens_hsa040220.59093282
83Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.56550842
84VEGF signaling pathway_Homo sapiens_hsa043700.54808934
85Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.52600619
86Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.52328894
87Butanoate metabolism_Homo sapiens_hsa006500.52224606
88Glutathione metabolism_Homo sapiens_hsa004800.51836309
89Phospholipase D signaling pathway_Homo sapiens_hsa040720.51229796
90Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49939331
91Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49595470
92RNA transport_Homo sapiens_hsa030130.47423016
93N-Glycan biosynthesis_Homo sapiens_hsa005100.47061223
94Gap junction_Homo sapiens_hsa045400.47055220
95Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.46943215
96Nucleotide excision repair_Homo sapiens_hsa034200.46541720
97MAPK signaling pathway_Homo sapiens_hsa040100.46466089
98Maturity onset diabetes of the young_Homo sapiens_hsa049500.46381266
99Hepatitis C_Homo sapiens_hsa051600.46228399
100mRNA surveillance pathway_Homo sapiens_hsa030150.45677947

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »