TANC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.11027534
2vocalization behavior (GO:0071625)5.03242490
3regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.95832135
4neuron cell-cell adhesion (GO:0007158)4.94554114
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.89952893
6locomotory exploration behavior (GO:0035641)4.63930423
7synaptic vesicle exocytosis (GO:0016079)4.59128293
8synaptic vesicle maturation (GO:0016188)4.51520619
9protein localization to synapse (GO:0035418)4.51453848
10regulation of glutamate receptor signaling pathway (GO:1900449)4.50435371
11ionotropic glutamate receptor signaling pathway (GO:0035235)4.47102682
12positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.32546417
13regulation of synaptic vesicle exocytosis (GO:2000300)4.19501670
14glutamate secretion (GO:0014047)4.18084221
15regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.07312144
16glutamate receptor signaling pathway (GO:0007215)4.04988444
17synaptic vesicle docking involved in exocytosis (GO:0016081)3.97644971
18neuron recognition (GO:0008038)3.96295199
19neuronal action potential propagation (GO:0019227)3.88382049
20dendritic spine morphogenesis (GO:0060997)3.86686805
21exploration behavior (GO:0035640)3.85693288
22synaptic transmission, glutamatergic (GO:0035249)3.81627069
23regulation of long-term neuronal synaptic plasticity (GO:0048169)3.80491620
24regulation of neuronal synaptic plasticity (GO:0048168)3.74455921
25axonal fasciculation (GO:0007413)3.71871102
26regulation of synaptic vesicle transport (GO:1902803)3.69007994
27postsynaptic membrane organization (GO:0001941)3.67501699
28regulation of synapse structural plasticity (GO:0051823)3.66735552
29membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.66540238
30layer formation in cerebral cortex (GO:0021819)3.65500254
31neuron-neuron synaptic transmission (GO:0007270)3.63935880
32presynaptic membrane assembly (GO:0097105)3.63674853
33regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.58273310
34neurotransmitter secretion (GO:0007269)3.53769387
35regulation of excitatory postsynaptic membrane potential (GO:0060079)3.50564370
36regulation of axon extension involved in axon guidance (GO:0048841)3.50513871
37neurotransmitter-gated ion channel clustering (GO:0072578)3.49848485
38regulation of axon guidance (GO:1902667)3.44439139
39long-term memory (GO:0007616)3.40149933
40regulation of postsynaptic membrane potential (GO:0060078)3.40001350
41dendrite morphogenesis (GO:0048813)3.32219622
42presynaptic membrane organization (GO:0097090)3.29748823
43gamma-aminobutyric acid signaling pathway (GO:0007214)3.26488852
44proline transport (GO:0015824)3.26231269
45gamma-aminobutyric acid transport (GO:0015812)3.23397718
46regulation of synaptic transmission, glutamatergic (GO:0051966)3.22452112
47regulation of dendritic spine morphogenesis (GO:0061001)3.20661298
48positive regulation of membrane potential (GO:0045838)3.20110537
49negative regulation of synaptic transmission, GABAergic (GO:0032229)3.18657271
50response to auditory stimulus (GO:0010996)3.18288018
51synaptic vesicle endocytosis (GO:0048488)3.18124081
52transmission of nerve impulse (GO:0019226)3.17501731
53long-term synaptic potentiation (GO:0060291)3.15712081
54regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.14824810
55regulation of synaptic plasticity (GO:0048167)3.13457545
56cerebellar Purkinje cell differentiation (GO:0021702)3.09834392
57auditory behavior (GO:0031223)3.09591445
58positive regulation of synaptic transmission, GABAergic (GO:0032230)3.09003919
59regulation of neurotransmitter secretion (GO:0046928)3.05648896
60regulation of dendritic spine development (GO:0060998)3.03191535
61positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.01975921
62membrane depolarization (GO:0051899)3.01824506
63G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.00017664
64neurotransmitter transport (GO:0006836)2.99300074
65cellular potassium ion homeostasis (GO:0030007)2.94800812
66membrane hyperpolarization (GO:0060081)2.93858430
67negative regulation of axon guidance (GO:1902668)2.93728678
68synapse assembly (GO:0007416)2.93390126
69negative regulation of axon extension involved in axon guidance (GO:0048843)2.92584240
70startle response (GO:0001964)2.88900027
71neuromuscular process controlling balance (GO:0050885)2.88621043
72activation of protein kinase A activity (GO:0034199)2.88082025
73positive regulation of neurotransmitter secretion (GO:0001956)2.87623260
74regulation of vesicle fusion (GO:0031338)2.87391269
75G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.87230605
76membrane depolarization during action potential (GO:0086010)2.86668329
77learning (GO:0007612)2.86423499
78hemidesmosome assembly (GO:0031581)2.85860458
79negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.85707020
80positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.85550184
81cell migration in hindbrain (GO:0021535)2.85482332
82response to histamine (GO:0034776)2.83650047
83central nervous system projection neuron axonogenesis (GO:0021952)2.83366283
84positive regulation of synapse maturation (GO:0090129)2.83217624
85positive regulation of dendritic spine development (GO:0060999)2.80514753
86regulation of neurotransmitter transport (GO:0051588)2.80220025
87behavioral defense response (GO:0002209)2.79570977
88behavioral fear response (GO:0001662)2.79570977
89negative regulation of keratinocyte proliferation (GO:0010839)2.77250417
90positive regulation of neurotransmitter transport (GO:0051590)2.77218913
91regulation of synaptic transmission, GABAergic (GO:0032228)2.74962033
92mechanosensory behavior (GO:0007638)2.74550544
93desmosome organization (GO:0002934)2.74415141
94central nervous system neuron axonogenesis (GO:0021955)2.72022608
95dendritic spine organization (GO:0097061)2.70783541
96innervation (GO:0060384)2.70052493
97vesicle transport along microtubule (GO:0047496)2.69684272
98regulation of neurotransmitter levels (GO:0001505)2.69269319
99positive regulation of synapse assembly (GO:0051965)2.69054045
100fear response (GO:0042596)2.68496200
101L-amino acid import (GO:0043092)2.68241300
102synapse organization (GO:0050808)2.67996571
103positive regulation of synaptic transmission (GO:0050806)2.67564388
104regulation of respiratory system process (GO:0044065)2.65593044
105regulation of synaptic transmission (GO:0050804)2.65227378
106neuronal ion channel clustering (GO:0045161)2.64183597
107adult walking behavior (GO:0007628)2.63091509
108dendrite development (GO:0016358)2.61734973
109apical protein localization (GO:0045176)2.59618168
110sodium ion export (GO:0071436)2.55556873
111axon extension involved in axon guidance (GO:0048846)2.54158617
112neuron projection extension involved in neuron projection guidance (GO:1902284)2.54158617
113axon extension (GO:0048675)2.53342693
114urinary tract smooth muscle contraction (GO:0014848)2.45482401
115pericardium development (GO:0060039)2.42561569
116fibroblast migration (GO:0010761)2.41273792
117positive regulation of action potential (GO:0045760)2.39913532
118neuron projection extension (GO:1990138)2.39441997
119cytoskeletal anchoring at plasma membrane (GO:0007016)2.39421418
120cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.35270008
121positive regulation of dendrite morphogenesis (GO:0050775)2.34983342
122negative chemotaxis (GO:0050919)2.34599457
123cranial nerve morphogenesis (GO:0021602)2.34387230
124ganglion development (GO:0061548)2.33389235
125membrane assembly (GO:0071709)2.31285018
126embryonic foregut morphogenesis (GO:0048617)2.28323865
127cranial nerve structural organization (GO:0021604)2.27923190
128positive regulation of axon extension (GO:0045773)2.27281692
129myelination in peripheral nervous system (GO:0022011)2.26907226
130peripheral nervous system axon ensheathment (GO:0032292)2.26907226
131cytoplasmic mRNA processing body assembly (GO:0033962)2.24723381
132cell communication involved in cardiac conduction (GO:0086065)2.21659952
133anatomical structure arrangement (GO:0048532)2.21569001
134artery development (GO:0060840)2.20764299
135establishment of nucleus localization (GO:0040023)2.20682757
136asymmetric protein localization (GO:0008105)2.20646153
137sympathetic nervous system development (GO:0048485)2.19912803
138regulation of synapse assembly (GO:0051963)2.17498631
139dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.17025002
140lymphangiogenesis (GO:0001946)2.16971487
141cerebral cortex radially oriented cell migration (GO:0021799)2.16194211
142facial nerve structural organization (GO:0021612)2.15853289
143regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.12977972
144endocardial cushion development (GO:0003197)2.12294863
145regulation of axon extension (GO:0030516)2.10949882
146organelle transport along microtubule (GO:0072384)2.09875630
147dermatan sulfate biosynthetic process (GO:0030208)2.09550561
148cell communication by electrical coupling (GO:0010644)2.08115003
149smooth muscle tissue development (GO:0048745)2.07872163
150negative regulation of axon extension (GO:0030517)2.06813547
151regulation of NFAT protein import into nucleus (GO:0051532)2.06640256
152negative regulation of protein localization to cell surface (GO:2000009)2.06346592
153positive regulation of dendrite development (GO:1900006)2.04088764
154cell adhesion mediated by integrin (GO:0033627)2.03910484
155developmental cell growth (GO:0048588)2.03116049
156semaphorin-plexin signaling pathway (GO:0071526)2.02753859
157limb development (GO:0060173)2.02683436
158appendage development (GO:0048736)2.02683436
159camera-type eye morphogenesis (GO:0048593)2.02408887
160negative regulation of dendrite development (GO:2000171)2.02218025
161embryonic retina morphogenesis in camera-type eye (GO:0060059)2.00754977
162pyrimidine nucleobase catabolic process (GO:0006208)1.98975982

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.51534067
2GBX2_23144817_ChIP-Seq_PC3_Human3.86793110
3JARID2_20064375_ChIP-Seq_MESCs_Mouse2.92172624
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.90551887
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.78821806
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.52372209
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.52372209
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.49706340
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.45015472
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.40244732
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.38533703
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.34718543
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.27703968
14* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.23589026
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.23458905
16DROSHA_22980978_ChIP-Seq_HELA_Human2.20660849
17GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.19073893
18REST_21632747_ChIP-Seq_MESCs_Mouse2.18162520
19RNF2_27304074_Chip-Seq_ESCs_Mouse2.04809952
20AR_21572438_ChIP-Seq_LNCaP_Human2.03692512
21ESR1_20079471_ChIP-ChIP_T-47D_Human2.03522646
22TAF15_26573619_Chip-Seq_HEK293_Human2.02020621
23* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.00922932
24EZH2_27294783_Chip-Seq_ESCs_Mouse2.00309605
25RARB_27405468_Chip-Seq_BRAIN_Mouse1.92782622
26SALL1_21062744_ChIP-ChIP_HESCs_Human1.90148024
27CTBP2_25329375_ChIP-Seq_LNCAP_Human1.88255433
28ZFP57_27257070_Chip-Seq_ESCs_Mouse1.79762747
29CTBP1_25329375_ChIP-Seq_LNCAP_Human1.76074855
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.75035014
31* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.72563194
32* SMAD4_21799915_ChIP-Seq_A2780_Human1.71858110
33ESR1_21235772_ChIP-Seq_MCF-7_Human1.70991760
34PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.69915270
35ESR2_21235772_ChIP-Seq_MCF-7_Human1.62049932
36IKZF1_21737484_ChIP-ChIP_HCT116_Human1.61742908
37CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.61097759
38SMAD_19615063_ChIP-ChIP_OVARY_Human1.60355670
39REST_18959480_ChIP-ChIP_MESCs_Mouse1.60203577
40* P300_19829295_ChIP-Seq_ESCs_Human1.56947737
41EP300_21415370_ChIP-Seq_HL-1_Mouse1.54805220
42RBPJ_22232070_ChIP-Seq_NCS_Mouse1.51433675
43CBX2_27304074_Chip-Seq_ESCs_Mouse1.49735487
44GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48886878
45CDX2_19796622_ChIP-Seq_MESCs_Mouse1.47992482
46CJUN_26792858_Chip-Seq_BT549_Human1.47712270
47TRIM28_21343339_ChIP-Seq_HEK293_Human1.47596697
48* SMAD3_21741376_ChIP-Seq_EPCs_Human1.47387019
49PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.46896983
50NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.46540975
51CTNNB1_20460455_ChIP-Seq_HCT116_Human1.45793307
52PIAS1_25552417_ChIP-Seq_VCAP_Human1.45317361
53* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.44581983
54* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.42715084
55RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.40472687
56BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.39106513
57* CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.37845130
58BMI1_23680149_ChIP-Seq_NPCS_Mouse1.37477317
59POU3F2_20337985_ChIP-ChIP_501MEL_Human1.37087542
60TOP2B_26459242_ChIP-Seq_MCF-7_Human1.36950826
61* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36348902
62ARNT_22903824_ChIP-Seq_MCF-7_Human1.35845461
63* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35072593
64IGF1R_20145208_ChIP-Seq_DFB_Human1.35009057
65AHR_22903824_ChIP-Seq_MCF-7_Human1.34793110
66ZNF274_21170338_ChIP-Seq_K562_Hela1.34032884
67SOX2_21211035_ChIP-Seq_LN229_Gbm1.31862060
68TP63_17297297_ChIP-ChIP_HaCaT_Human1.31137872
69* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.30054032
70* STAT3_23295773_ChIP-Seq_U87_Human1.29992227
71AR_25329375_ChIP-Seq_VCAP_Human1.29838030
72NR3C1_23031785_ChIP-Seq_PC12_Mouse1.29509140
73TP53_16413492_ChIP-PET_HCT116_Human1.29211666
74AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.26481145
75MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.23090707
76EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.22588334
77TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.21273784
78* RNF2_27304074_Chip-Seq_NSC_Mouse1.21138009
79EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.20552657
80ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.19067125
81FUS_26573619_Chip-Seq_HEK293_Human1.17714398
82* NRF2_20460467_ChIP-Seq_MEFs_Mouse1.16868126
83* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.16868126
84* TCF4_23295773_ChIP-Seq_U87_Human1.16164083
85* RING1B_27294783_Chip-Seq_ESCs_Mouse1.16034669
86* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.15876483
87* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.14463537
88VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.14413862
89ERG_21242973_ChIP-ChIP_JURKAT_Human1.13971015
90AR_19668381_ChIP-Seq_PC3_Human1.13763623
91P53_22127205_ChIP-Seq_FIBROBLAST_Human1.13261435
92NR3C1_21868756_ChIP-Seq_MCF10A_Human1.13143465
93SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.12558058
94UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.12113739
95RING1B_27294783_Chip-Seq_NPCs_Mouse1.10622113
96RUNX2_22187159_ChIP-Seq_PCA_Human1.10493618
97* BRD4_25478319_ChIP-Seq_HGPS_Human1.10335304
98* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.09240923
99STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.08862268
100* TP53_18474530_ChIP-ChIP_U2OS_Human1.08446984
101ISL1_27105846_Chip-Seq_CPCs_Mouse1.08018025
102POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.07560598
103TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07560598
104TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.06033334
105* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.05665405
106RXR_22108803_ChIP-Seq_LS180_Human1.05570841
107ER_23166858_ChIP-Seq_MCF-7_Human1.05514350
108PRDM14_20953172_ChIP-Seq_ESCs_Human1.05268215
109LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05054115
110CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04742455
111TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03308662
112MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01433743
113NANOG_18555785_Chip-Seq_ESCs_Mouse1.00840382
114SMAD3_21741376_ChIP-Seq_HESCs_Human0.98945227
115ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.98629495
116SMAD4_21741376_ChIP-Seq_HESCs_Human0.95869536
117TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.95110187
118* SMAD3_21741376_ChIP-Seq_ESCs_Human0.92810718
119VDR_22108803_ChIP-Seq_LS180_Human0.92001084
120WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.90356491
121TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.89932562
122JUN_21703547_ChIP-Seq_K562_Human0.88409547
123MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.88160248

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.78140728
2MP0003880_abnormal_central_pattern4.87182210
3MP0003635_abnormal_synaptic_transmissio3.89990520
4MP0004270_analgesia3.80848234
5MP0009745_abnormal_behavioral_response3.18305597
6MP0002063_abnormal_learning/memory/cond3.15820788
7MP0002064_seizures2.97887310
8MP0001968_abnormal_touch/_nociception2.93024532
9MP0009046_muscle_twitch2.77966042
10MP0002572_abnormal_emotion/affect_behav2.74032601
11MP0005423_abnormal_somatic_nervous2.73660255
12MP0001486_abnormal_startle_reflex2.64631624
13MP0002734_abnormal_mechanical_nocicepti2.57764149
14MP0002272_abnormal_nervous_system2.39732452
15MP0002736_abnormal_nociception_after2.22310324
16MP0002735_abnormal_chemical_nociception2.21301081
17MP0000778_abnormal_nervous_system2.16762402
18MP0002822_catalepsy2.15055837
19MP0001501_abnormal_sleep_pattern2.11231507
20MP0001440_abnormal_grooming_behavior2.04782907
21MP0002067_abnormal_sensory_capabilities1.97204970
22MP0002733_abnormal_thermal_nociception1.91216198
23MP0002557_abnormal_social/conspecific_i1.90153526
24MP0000579_abnormal_nail_morphology1.89370049
25MP0009780_abnormal_chondrocyte_physiolo1.88645465
26MP0001970_abnormal_pain_threshold1.88464320
27MP0002184_abnormal_innervation1.86972048
28MP0003787_abnormal_imprinting1.86184652
29MP0000534_abnormal_ureter_morphology1.80930771
30MP0000383_abnormal_hair_follicle1.79970214
31MP0000569_abnormal_digit_pigmentation1.77725667
32MP0001984_abnormal_olfaction1.76248129
33MP0001188_hyperpigmentation1.73277623
34MP0005646_abnormal_pituitary_gland1.68310451
35MP0006276_abnormal_autonomic_nervous1.63952291
36MP0005645_abnormal_hypothalamus_physiol1.61685761
37MP0004924_abnormal_behavior1.61502813
38MP0005386_behavior/neurological_phenoty1.61502813
39MP0010678_abnormal_skin_adnexa1.61395584
40MP0004811_abnormal_neuron_physiology1.60611538
41MP0004858_abnormal_nervous_system1.59796554
42MP0008569_lethality_at_weaning1.58266580
43MP0003942_abnormal_urinary_system1.56820630
44MP0004272_abnormal_basement_membrane1.53337657
45MP0003879_abnormal_hair_cell1.51816515
46MP0008438_abnormal_cutaneous_collagen1.50454704
47MP0005275_abnormal_skin_tensile1.47754660
48MP0000955_abnormal_spinal_cord1.44745343
49MP0004885_abnormal_endolymph1.44383165
50MP0000427_abnormal_hair_cycle1.44106292
51MP0002882_abnormal_neuron_morphology1.43551475
52MP0003122_maternal_imprinting1.42596504
53MP0005503_abnormal_tendon_morphology1.40415538
54MP0003705_abnormal_hypodermis_morpholog1.40016662
55MP0002909_abnormal_adrenal_gland1.35212075
56MP0000537_abnormal_urethra_morphology1.33283512
57MP0002066_abnormal_motor_capabilities/c1.32438257
58MP0003329_amyloid_beta_deposits1.30903833
59MP0004742_abnormal_vestibular_system1.28765906
60MP0004233_abnormal_muscle_weight1.28160263
61MP0005187_abnormal_penis_morphology1.26981294
62MP0005409_darkened_coat_color1.26804068
63MP0003633_abnormal_nervous_system1.25498139
64MP0001502_abnormal_circadian_rhythm1.23440453
65MP0005248_abnormal_Harderian_gland1.22735016
66MP0000538_abnormal_urinary_bladder1.21388695
67MP0004142_abnormal_muscle_tone1.18758673
68MP0000462_abnormal_digestive_system1.17047215
69MP0001529_abnormal_vocalization1.16548406
70MP0005257_abnormal_intraocular_pressure1.14552179
71MP0004145_abnormal_muscle_electrophysio1.14256731
72MP0002152_abnormal_brain_morphology1.13708066
73MP0001905_abnormal_dopamine_level1.13673899
74MP0003755_abnormal_palate_morphology1.13362851
75MP0003283_abnormal_digestive_organ1.11721616
76MP0001958_emphysema1.10196838
77MP0009250_abnormal_appendicular_skeleto1.09681169
78MP0009384_cardiac_valve_regurgitation1.05370338
79MP0003935_abnormal_craniofacial_develop1.05315200
80MP0003937_abnormal_limbs/digits/tail_de1.04618093
81MP0003631_nervous_system_phenotype1.04145669
82MP0000631_abnormal_neuroendocrine_gland1.02288050
83MP0002751_abnormal_autonomic_nervous1.01541661
84MP0001963_abnormal_hearing_physiology1.01235815
85MP0010386_abnormal_urinary_bladder0.99535350
86MP0002896_abnormal_bone_mineralization0.98338185
87MP0000751_myopathy0.97516501
88MP0005076_abnormal_cell_differentiation0.95852978
89MP0000762_abnormal_tongue_morphology0.95783406
90MP0001177_atelectasis0.95498257
91MP0002229_neurodegeneration0.94644516
92MP0002234_abnormal_pharynx_morphology0.93217828
93MP0003385_abnormal_body_wall0.93159466
94MP0001879_abnormal_lymphatic_vessel0.91823133
95MP0009053_abnormal_anal_canal0.91636368
96MP0000920_abnormal_myelination0.91129274
97MP0003690_abnormal_glial_cell0.90614197
98MP0005551_abnormal_eye_electrophysiolog0.90491460
99MP0003634_abnormal_glial_cell0.90396371
100MP0010368_abnormal_lymphatic_system0.88882808
101MP0003950_abnormal_plasma_membrane0.88749008
102MP0003890_abnormal_embryonic-extraembry0.88358379
103MP0003091_abnormal_cell_migration0.87659691
104MP0002069_abnormal_eating/drinking_beha0.87510948
105MP0004085_abnormal_heartbeat0.86572111
106MP0002752_abnormal_somatic_nervous0.86172475
107MP0002116_abnormal_craniofacial_bone0.85983797
108MP0003115_abnormal_respiratory_system0.85685347
109MP0004134_abnormal_chest_morphology0.84817673
110MP0002108_abnormal_muscle_morphology0.83418690
111MP0001299_abnormal_eye_distance/0.83209322
112MP0000428_abnormal_craniofacial_morphol0.83164072
113MP0000013_abnormal_adipose_tissue0.82072218
114MP0001485_abnormal_pinna_reflex0.81465454
115MP0005394_taste/olfaction_phenotype0.79889508
116MP0005499_abnormal_olfactory_system0.79889508
117MP0000003_abnormal_adipose_tissue0.79372183
118MP0004484_altered_response_of0.78896388
119MP0000733_abnormal_muscle_development0.76013729
120MP0002081_perinatal_lethality0.75723878
121MP0008874_decreased_physiological_sensi0.75426538
122MP0000432_abnormal_head_morphology0.73927954
123MP0001664_abnormal_digestion0.73533192
124MP0005171_absent_coat_pigmentation0.73327002
125MP0002249_abnormal_larynx_morphology0.73294081
126MP0000647_abnormal_sebaceous_gland0.73054159
127MP0008872_abnormal_physiological_respon0.72457477
128MP0002102_abnormal_ear_morphology0.70879435
129MP0003045_fibrosis0.70450753
130MP0002090_abnormal_vision0.68982232
131MP0003632_abnormal_nervous_system0.68386799
132MP0002638_abnormal_pupillary_reflex0.68121243
133MP0003172_abnormal_lysosome_physiology0.67971929
134MP0000026_abnormal_inner_ear0.66384664
135MP0003861_abnormal_nervous_system0.65447953
136MP0004510_myositis0.64716594
137MP0001943_abnormal_respiration0.64697923
138MP0008961_abnormal_basal_metabolism0.63867799
139MP0000015_abnormal_ear_pigmentation0.63226822
140MP0003121_genomic_imprinting0.62736753
141MP0005623_abnormal_meninges_morphology0.62614513
142MP0003137_abnormal_impulse_conducting0.61836803
143MP0005535_abnormal_body_temperature0.60204138
144MP0010770_preweaning_lethality0.54153698
145MP0002082_postnatal_lethality0.54153698
146MP0002876_abnormal_thyroid_physiology0.53657183
147MP0004215_abnormal_myocardial_fiber0.52762880
148MP0010769_abnormal_survival0.52200241
149MP0003075_altered_response_to0.52081953

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.11566779
2Focal seizures (HP:0007359)5.38615175
3Myokymia (HP:0002411)5.30597482
4Epileptic encephalopathy (HP:0200134)4.68724147
5Febrile seizures (HP:0002373)4.33032506
6Atonic seizures (HP:0010819)4.13484234
7Visual hallucinations (HP:0002367)3.98569538
8Progressive cerebellar ataxia (HP:0002073)3.96206451
9Broad-based gait (HP:0002136)3.76707845
10Hyperventilation (HP:0002883)3.61309539
11Absence seizures (HP:0002121)3.58248488
12Generalized tonic-clonic seizures (HP:0002069)3.48784065
13Action tremor (HP:0002345)3.40071898
14Supranuclear gaze palsy (HP:0000605)3.38834696
15Dialeptic seizures (HP:0011146)3.37621516
16Mutism (HP:0002300)3.33613416
17Excessive salivation (HP:0003781)3.20665775
18Drooling (HP:0002307)3.20665775
19Gaze-evoked nystagmus (HP:0000640)3.16022391
20Truncal ataxia (HP:0002078)2.97774945
21Genetic anticipation (HP:0003743)2.94233592
22Urinary bladder sphincter dysfunction (HP:0002839)2.92535193
23Ankle clonus (HP:0011448)2.84926346
24Poor eye contact (HP:0000817)2.80420055
25Amblyopia (HP:0000646)2.77666378
26Absent frontal sinuses (HP:0002688)2.74159651
27Dysdiadochokinesis (HP:0002075)2.70402053
28Absent speech (HP:0001344)2.67020566
29Impaired vibration sensation in the lower limbs (HP:0002166)2.65406491
30Abnormal eating behavior (HP:0100738)2.65351680
31Neurofibrillary tangles (HP:0002185)2.62582431
32Dysmetria (HP:0001310)2.58274082
33Postural instability (HP:0002172)2.56357933
34Depression (HP:0000716)2.52664822
35Impaired social interactions (HP:0000735)2.48914713
36Abnormal social behavior (HP:0012433)2.48914713
37Termporal pattern (HP:0011008)2.48512665
38Insidious onset (HP:0003587)2.48512665
39Atrophic scars (HP:0001075)2.48073828
40Abnormality of the corticospinal tract (HP:0002492)2.44934378
41Hemiparesis (HP:0001269)2.44817410
42Exotropia (HP:0000577)2.44634142
43Polyphagia (HP:0002591)2.43433043
44Cerebral inclusion bodies (HP:0100314)2.42800575
45Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.40520559
46Obstructive sleep apnea (HP:0002870)2.40098044
47Macroorchidism (HP:0000053)2.38286167
48Anxiety (HP:0000739)2.38142585
49Papilledema (HP:0001085)2.37286036
50Abnormality of binocular vision (HP:0011514)2.36116120
51Diplopia (HP:0000651)2.36116120
52Stereotypic behavior (HP:0000733)2.34617219
53Limb dystonia (HP:0002451)2.30833757
54Urinary urgency (HP:0000012)2.27391623
55Scanning speech (HP:0002168)2.26431903
56Inappropriate behavior (HP:0000719)2.25205511
57Epileptiform EEG discharges (HP:0011182)2.24230034
58Progressive inability to walk (HP:0002505)2.24054638
59Abnormality of salivation (HP:0100755)2.22811749
60Inability to walk (HP:0002540)2.22311424
61Heterotopia (HP:0002282)2.20236151
62Impaired smooth pursuit (HP:0007772)2.19523410
63Fetal akinesia sequence (HP:0001989)2.15110558
64Blue irides (HP:0000635)2.13394514
65Broad face (HP:0000283)2.12340227
66Widely spaced teeth (HP:0000687)2.11744365
67Torticollis (HP:0000473)2.11212278
68Spastic gait (HP:0002064)2.11075382
69Vascular tortuosity (HP:0004948)2.10434840
70Papillary thyroid carcinoma (HP:0002895)2.10406191
71EEG with generalized epileptiform discharges (HP:0011198)2.10072173
72Protruding tongue (HP:0010808)2.03267529
73Abnormality of the ischium (HP:0003174)2.02581623
74Aqueductal stenosis (HP:0002410)2.02423024
75Hemiplegia (HP:0002301)2.01798823
76Sleep apnea (HP:0010535)1.99589897
77Bradykinesia (HP:0002067)1.98871022
78Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.98583694
79Degeneration of the lateral corticospinal tracts (HP:0002314)1.98583694
80Agitation (HP:0000713)1.97530517
81Abnormality of the frontal sinuses (HP:0002687)1.97066773
82Dynein arm defect of respiratory motile cilia (HP:0012255)1.95847639
83Absent/shortened dynein arms (HP:0200106)1.95847639
84Hypsarrhythmia (HP:0002521)1.92561173
85Lower limb muscle weakness (HP:0007340)1.92472432
86Gait imbalance (HP:0002141)1.90746924
87Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.90508663
88Neuronal loss in central nervous system (HP:0002529)1.90340113
89Open mouth (HP:0000194)1.88316405
90Focal dystonia (HP:0004373)1.88007570
91Short nail (HP:0001799)1.86619446
92Shawl scrotum (HP:0000049)1.85574786
93Morphological abnormality of the middle ear (HP:0008609)1.85187830
94Megalencephaly (HP:0001355)1.85077584
95Impaired vibratory sensation (HP:0002495)1.84615403
96Generalized hypopigmentation of hair (HP:0011358)1.84084394
97Abnormality of ocular smooth pursuit (HP:0000617)1.83206863
98Clumsiness (HP:0002312)1.83110122
99Lower limb amyotrophy (HP:0007210)1.81203704
100Shallow orbits (HP:0000586)1.79397254
101Generalized myoclonic seizures (HP:0002123)1.78830681
102Aplasia involving bones of the extremities (HP:0009825)1.78219111
103Aplasia involving bones of the upper limbs (HP:0009823)1.78219111
104Aplasia of the phalanges of the hand (HP:0009802)1.78219111
105Intention tremor (HP:0002080)1.78153426
106Hypoplastic ischia (HP:0003175)1.76878158
107Lower limb asymmetry (HP:0100559)1.75930463
108Specific learning disability (HP:0001328)1.75921790
109Gastroesophageal reflux (HP:0002020)1.75433968
110Abnormal hair whorl (HP:0010721)1.74933513
111Thickened helices (HP:0000391)1.74665029
112Abnormal ciliary motility (HP:0012262)1.74609007
113Increased number of teeth (HP:0011069)1.74574823
114Dysmetric saccades (HP:0000641)1.73396458
115Status epilepticus (HP:0002133)1.73146506
116Hypoventilation (HP:0002791)1.71350412
117Arterial tortuosity (HP:0005116)1.71063364
118Retinal dysplasia (HP:0007973)1.70707829
119Bronchomalacia (HP:0002780)1.69989610
120Microglossia (HP:0000171)1.69412398
121Overgrowth (HP:0001548)1.66599203
122Aortic dissection (HP:0002647)1.61808859
123Tented upper lip vermilion (HP:0010804)1.60357501
124Aortic aneurysm (HP:0004942)1.60112363
125Tibial bowing (HP:0002982)1.59043495
126Laryngomalacia (HP:0001601)1.58565038
127Pulmonic stenosis (HP:0001642)1.57652909
128Hypoplastic nipples (HP:0002557)1.56473346
129Buphthalmos (HP:0000557)1.56446588
130Cubitus valgus (HP:0002967)1.56136934
131Spondylolisthesis (HP:0003302)1.55153027
132Hypoplastic labia majora (HP:0000059)1.54671909
133Bell-shaped thorax (HP:0001591)1.54563858
134Hypopigmentation of the fundus (HP:0007894)1.52198283
135Midline defect of the nose (HP:0004122)1.51675405
136Hyperacusis (HP:0010780)1.50527677
137Abnormality of the nasal septum (HP:0000419)1.50364447
138Milia (HP:0001056)1.50303956
139Astrocytoma (HP:0009592)1.49781907
140Abnormality of the astrocytes (HP:0100707)1.49781907
141Ulnar bowing (HP:0003031)1.49591416
142Tracheomalacia (HP:0002779)1.49266942
143Cutaneous finger syndactyly (HP:0010554)1.49026141
144Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.47589064
145Abnormality of the sella turcica (HP:0002679)1.47579962
146Abnormality of the labia majora (HP:0012881)1.47553921
147Narrow palate (HP:0000189)1.46304455
148Asymmetry of the thorax (HP:0001555)1.45523303
149Wormian bones (HP:0002645)1.45238373
150Round face (HP:0000311)1.45202045
151Germ cell neoplasia (HP:0100728)1.45141787
152Abnormality of dentin (HP:0010299)1.44488293
153Long toe (HP:0010511)1.43923103
154Neoplasm of the heart (HP:0100544)1.43602915
155Short 4th metacarpal (HP:0010044)1.43442750
156Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.43442750
157Vertebral arch anomaly (HP:0008438)1.43371853
158Protrusio acetabuli (HP:0003179)1.42808124
159Relative macrocephaly (HP:0004482)1.42773841
160Coronal craniosynostosis (HP:0004440)1.42466361
161Bradycardia (HP:0001662)1.42400352
162Limited hip movement (HP:0008800)1.42233589
163Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.42068334
164Aplasia/Hypoplasia of the tibia (HP:0005772)1.41300176
165Aplasia of the musculature (HP:0100854)1.41282040
166Short chin (HP:0000331)1.41216793
167Abnormality of the distal phalanx of the thumb (HP:0009617)1.41183941
168Cerebellar dysplasia (HP:0007033)1.41069751
169Complete atrioventricular canal defect (HP:0001674)1.40563798
170Abnormality of the 2nd finger (HP:0004100)1.38777782
171Septate vagina (HP:0001153)1.37862268

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.04289127
2EPHA43.99539181
3MARK13.62376487
4FRK3.27292620
5MAP3K93.24567812
6CASK2.98362170
7MAP3K42.97585257
8MAP2K72.72905310
9MINK12.27438360
10NTRK22.16965263
11RIPK42.13820549
12DAPK21.99685221
13TNIK1.91082307
14PIK3CA1.88940825
15MAPK131.87690929
16PNCK1.82389798
17PAK61.81101534
18MAP2K41.78876637
19PKN21.76207491
20SIK21.70740000
21MAP3K121.67455257
22PDGFRA1.60917817
23CDK121.60025688
24PTK21.56969135
25PLK21.50460962
26NTRK11.49361680
27CAMK1G1.46075141
28SIK11.43837876
29MET1.42693381
30CDK51.42401277
31KSR11.40445065
32CAMKK11.36774581
33LATS11.26608710
34KSR21.26411531
35EPHB21.24780798
36GRK51.21791979
37PRKD31.21552999
38OXSR11.15742640
39FES1.13170292
40BRD41.12954561
41GRK71.12699131
42CAMKK21.12533275
43PHKG11.09608124
44PHKG21.09608124
45CDK191.09579348
46SGK4941.08696158
47SGK2231.08696158
48RPS6KA21.08168978
49MTOR1.07942835
50DAPK11.07678492
51PDGFRB1.03313808
52SGK21.03125945
53CAMK2A1.02066765
54EPHA21.01625872
55UHMK10.99499236
56CAMK10.97080363
57BMPR20.95465954
58PRKCG0.94980148
59PRPF4B0.93403185
60MARK20.91547408
61MST1R0.90737042
62DDR20.90130992
63TRIB30.89676050
64STK38L0.88032871
65MAP3K70.86338960
66STK110.86333089
67STK380.86069997
68CAMK2B0.85677523
69CSNK1A1L0.85223317
70ICK0.84771220
71PINK10.83852431
72SIK30.83708705
73PRKD20.81176030
74CSNK1G20.79955155
75SGK10.78621445
76DYRK1A0.77564940
77MAP3K20.76530074
78ROCK10.76332275
79MAP3K130.75966605
80RET0.73887195
81MUSK0.73174128
82SGK30.73140507
83RIPK10.73138023
84PTK2B0.72971421
85CDK30.71583550
86STK390.71186522
87PRKCE0.70195097
88LATS20.69612267
89CDK180.69329410
90PKN10.69023259
91LMTK20.68679853
92WNK30.68173964
93TRPM70.68044474
94AKT30.67506492
95PAK30.65957635
96SCYL20.65949566
97CDK150.65696378
98WNK10.65305837
99CDK140.65026301
100TYRO30.62819938
101CAMK1D0.62668771
102BMPR1B0.61555073
103MAPK120.60839555
104FER0.59332904
105MAP2K10.58648399
106MYLK0.58181822
107CAMK40.57463453
108NEK60.57162562
109MAP3K60.56905138
110CDK11A0.56222913
111MAPK150.54999435
112FGR0.54238882
113FGFR20.53583758
114ROCK20.53493041
115PRKCH0.53332094
116CCNB10.52690395
117MAPKAPK30.52672087
118DMPK0.52479824
119PRKCZ0.52039188
120CAMK2G0.51124255
121TAOK10.50350142
122MELK0.50076588
123PDPK10.49789359
124CDC42BPA0.48781770
125EPHB10.47000930
126PDK10.46924587
127RPS6KB10.46685501
128FYN0.46291445
129ERBB30.46045248
130WNK40.44742065
131MAPK100.43620305
132RAF10.43602493
133MAPKAPK50.43497237
134RPS6KA30.42906500
135PRKAA10.42569344
136BCR0.42561048
137ARAF0.41748611
138CAMK2D0.41517803
139CSNK1D0.41150315

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.52052812
2Synaptic vesicle cycle_Homo sapiens_hsa047212.67080726
3Olfactory transduction_Homo sapiens_hsa047402.60395600
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.55904329
5Circadian entrainment_Homo sapiens_hsa047132.49071617
6Glutamatergic synapse_Homo sapiens_hsa047242.43758747
7GABAergic synapse_Homo sapiens_hsa047272.39944086
8Morphine addiction_Homo sapiens_hsa050322.37092445
9Long-term potentiation_Homo sapiens_hsa047202.35912139
10Amphetamine addiction_Homo sapiens_hsa050312.23248049
11Salivary secretion_Homo sapiens_hsa049702.10560018
12Dopaminergic synapse_Homo sapiens_hsa047282.01867146
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.86315878
14Cholinergic synapse_Homo sapiens_hsa047251.82693805
15Renin secretion_Homo sapiens_hsa049241.80467981
16Insulin secretion_Homo sapiens_hsa049111.80283184
17Serotonergic synapse_Homo sapiens_hsa047261.78861779
18Gastric acid secretion_Homo sapiens_hsa049711.76939445
19Taste transduction_Homo sapiens_hsa047421.75221517
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.68173005
21Long-term depression_Homo sapiens_hsa047301.68091855
22Cocaine addiction_Homo sapiens_hsa050301.62977568
23Oxytocin signaling pathway_Homo sapiens_hsa049211.61541162
24Calcium signaling pathway_Homo sapiens_hsa040201.55635150
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.50393182
26Axon guidance_Homo sapiens_hsa043601.47118694
27GnRH signaling pathway_Homo sapiens_hsa049121.42287417
28Hippo signaling pathway_Homo sapiens_hsa043901.41109757
29Collecting duct acid secretion_Homo sapiens_hsa049661.38618621
30ECM-receptor interaction_Homo sapiens_hsa045121.34594058
31Gap junction_Homo sapiens_hsa045401.32930276
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.32642639
33Adherens junction_Homo sapiens_hsa045201.32171821
34cAMP signaling pathway_Homo sapiens_hsa040241.30469467
35Focal adhesion_Homo sapiens_hsa045101.28874051
36Hedgehog signaling pathway_Homo sapiens_hsa043401.26291520
37Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.26079920
38Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.25016124
39Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.22276508
40Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.15335779
41Estrogen signaling pathway_Homo sapiens_hsa049151.13983310
42ErbB signaling pathway_Homo sapiens_hsa040121.13715449
43Type II diabetes mellitus_Homo sapiens_hsa049301.12494301
44cGMP-PKG signaling pathway_Homo sapiens_hsa040221.10520584
45Phosphatidylinositol signaling system_Homo sapiens_hsa040701.10407734
46Tight junction_Homo sapiens_hsa045301.09684481
47TGF-beta signaling pathway_Homo sapiens_hsa043501.08731092
48Glioma_Homo sapiens_hsa052141.06728341
49Melanogenesis_Homo sapiens_hsa049161.06028402
50Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.00330539
51Proteoglycans in cancer_Homo sapiens_hsa052050.96117149
52Dorso-ventral axis formation_Homo sapiens_hsa043200.95797156
53Phototransduction_Homo sapiens_hsa047440.94985334
54Vascular smooth muscle contraction_Homo sapiens_hsa042700.94328665
55Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.94161730
56Vibrio cholerae infection_Homo sapiens_hsa051100.93579409
57MicroRNAs in cancer_Homo sapiens_hsa052060.92756625
58Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.91295361
59Dilated cardiomyopathy_Homo sapiens_hsa054140.90549081
60Basal cell carcinoma_Homo sapiens_hsa052170.86208899
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.85778325
62Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.84413491
63Pancreatic secretion_Homo sapiens_hsa049720.83609335
64MAPK signaling pathway_Homo sapiens_hsa040100.81331748
65Choline metabolism in cancer_Homo sapiens_hsa052310.80984154
66Lysine degradation_Homo sapiens_hsa003100.78812838
67Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.77719054
68AMPK signaling pathway_Homo sapiens_hsa041520.77658387
69Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.77502200
70Ras signaling pathway_Homo sapiens_hsa040140.76582896
71Cardiac muscle contraction_Homo sapiens_hsa042600.75903661
72Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.74841848
73Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.74190058
74Rap1 signaling pathway_Homo sapiens_hsa040150.72551663
75Bile secretion_Homo sapiens_hsa049760.70152326
76Prostate cancer_Homo sapiens_hsa052150.70039513
77AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.68529500
78Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.68504558
79Neurotrophin signaling pathway_Homo sapiens_hsa047220.68328494
80Prolactin signaling pathway_Homo sapiens_hsa049170.67546846
81Wnt signaling pathway_Homo sapiens_hsa043100.66206725
82Thyroid hormone synthesis_Homo sapiens_hsa049180.65052147
83FoxO signaling pathway_Homo sapiens_hsa040680.64361273
84Sphingolipid signaling pathway_Homo sapiens_hsa040710.64331669
85Renal cell carcinoma_Homo sapiens_hsa052110.63876235
86PI3K-Akt signaling pathway_Homo sapiens_hsa041510.63512887
87Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.63295968
88Chronic myeloid leukemia_Homo sapiens_hsa052200.61676725
89Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.60555148
90Amoebiasis_Homo sapiens_hsa051460.60518501
91Pathways in cancer_Homo sapiens_hsa052000.60127556
92Protein digestion and absorption_Homo sapiens_hsa049740.58823273
93Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.58231451
94Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.57400339
95Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.57374606
96Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.56590978
97Thyroid hormone signaling pathway_Homo sapiens_hsa049190.56513907
98VEGF signaling pathway_Homo sapiens_hsa043700.55745845
99Oocyte meiosis_Homo sapiens_hsa041140.55647443
100Inositol phosphate metabolism_Homo sapiens_hsa005620.53668221
101Ovarian steroidogenesis_Homo sapiens_hsa049130.53228443
102Carbohydrate digestion and absorption_Homo sapiens_hsa049730.53050463
103Endometrial cancer_Homo sapiens_hsa052130.51315984
104Circadian rhythm_Homo sapiens_hsa047100.50431647
105Prion diseases_Homo sapiens_hsa050200.50418778
106Endocytosis_Homo sapiens_hsa041440.50342299
107African trypanosomiasis_Homo sapiens_hsa051430.47467394
108Colorectal cancer_Homo sapiens_hsa052100.47204195
109Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.45913945
110Glucagon signaling pathway_Homo sapiens_hsa049220.45871978
111Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.45373207
112Chemokine signaling pathway_Homo sapiens_hsa040620.43839928
113Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43163978
114Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.42293656
115Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.40914612
116Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.40401139
117Alcoholism_Homo sapiens_hsa050340.39644713
118Regulation of actin cytoskeleton_Homo sapiens_hsa048100.39249213
119mTOR signaling pathway_Homo sapiens_hsa041500.39066328
120Platelet activation_Homo sapiens_hsa046110.38278921
121Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.37549663
122Non-small cell lung cancer_Homo sapiens_hsa052230.37233346
123Insulin signaling pathway_Homo sapiens_hsa049100.35416322
124Rheumatoid arthritis_Homo sapiens_hsa053230.34134444
125Melanoma_Homo sapiens_hsa052180.31549906

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