Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.11027534 |
2 | vocalization behavior (GO:0071625) | 5.03242490 |
3 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.95832135 |
4 | neuron cell-cell adhesion (GO:0007158) | 4.94554114 |
5 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.89952893 |
6 | locomotory exploration behavior (GO:0035641) | 4.63930423 |
7 | synaptic vesicle exocytosis (GO:0016079) | 4.59128293 |
8 | synaptic vesicle maturation (GO:0016188) | 4.51520619 |
9 | protein localization to synapse (GO:0035418) | 4.51453848 |
10 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.50435371 |
11 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.47102682 |
12 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.32546417 |
13 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.19501670 |
14 | glutamate secretion (GO:0014047) | 4.18084221 |
15 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.07312144 |
16 | glutamate receptor signaling pathway (GO:0007215) | 4.04988444 |
17 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.97644971 |
18 | neuron recognition (GO:0008038) | 3.96295199 |
19 | neuronal action potential propagation (GO:0019227) | 3.88382049 |
20 | dendritic spine morphogenesis (GO:0060997) | 3.86686805 |
21 | exploration behavior (GO:0035640) | 3.85693288 |
22 | synaptic transmission, glutamatergic (GO:0035249) | 3.81627069 |
23 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.80491620 |
24 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.74455921 |
25 | axonal fasciculation (GO:0007413) | 3.71871102 |
26 | regulation of synaptic vesicle transport (GO:1902803) | 3.69007994 |
27 | postsynaptic membrane organization (GO:0001941) | 3.67501699 |
28 | regulation of synapse structural plasticity (GO:0051823) | 3.66735552 |
29 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.66540238 |
30 | layer formation in cerebral cortex (GO:0021819) | 3.65500254 |
31 | neuron-neuron synaptic transmission (GO:0007270) | 3.63935880 |
32 | presynaptic membrane assembly (GO:0097105) | 3.63674853 |
33 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.58273310 |
34 | neurotransmitter secretion (GO:0007269) | 3.53769387 |
35 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.50564370 |
36 | regulation of axon extension involved in axon guidance (GO:0048841) | 3.50513871 |
37 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.49848485 |
38 | regulation of axon guidance (GO:1902667) | 3.44439139 |
39 | long-term memory (GO:0007616) | 3.40149933 |
40 | regulation of postsynaptic membrane potential (GO:0060078) | 3.40001350 |
41 | dendrite morphogenesis (GO:0048813) | 3.32219622 |
42 | presynaptic membrane organization (GO:0097090) | 3.29748823 |
43 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.26488852 |
44 | proline transport (GO:0015824) | 3.26231269 |
45 | gamma-aminobutyric acid transport (GO:0015812) | 3.23397718 |
46 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.22452112 |
47 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.20661298 |
48 | positive regulation of membrane potential (GO:0045838) | 3.20110537 |
49 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.18657271 |
50 | response to auditory stimulus (GO:0010996) | 3.18288018 |
51 | synaptic vesicle endocytosis (GO:0048488) | 3.18124081 |
52 | transmission of nerve impulse (GO:0019226) | 3.17501731 |
53 | long-term synaptic potentiation (GO:0060291) | 3.15712081 |
54 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.14824810 |
55 | regulation of synaptic plasticity (GO:0048167) | 3.13457545 |
56 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.09834392 |
57 | auditory behavior (GO:0031223) | 3.09591445 |
58 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.09003919 |
59 | regulation of neurotransmitter secretion (GO:0046928) | 3.05648896 |
60 | regulation of dendritic spine development (GO:0060998) | 3.03191535 |
61 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.01975921 |
62 | membrane depolarization (GO:0051899) | 3.01824506 |
63 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.00017664 |
64 | neurotransmitter transport (GO:0006836) | 2.99300074 |
65 | cellular potassium ion homeostasis (GO:0030007) | 2.94800812 |
66 | membrane hyperpolarization (GO:0060081) | 2.93858430 |
67 | negative regulation of axon guidance (GO:1902668) | 2.93728678 |
68 | synapse assembly (GO:0007416) | 2.93390126 |
69 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.92584240 |
70 | startle response (GO:0001964) | 2.88900027 |
71 | neuromuscular process controlling balance (GO:0050885) | 2.88621043 |
72 | activation of protein kinase A activity (GO:0034199) | 2.88082025 |
73 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.87623260 |
74 | regulation of vesicle fusion (GO:0031338) | 2.87391269 |
75 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.87230605 |
76 | membrane depolarization during action potential (GO:0086010) | 2.86668329 |
77 | learning (GO:0007612) | 2.86423499 |
78 | hemidesmosome assembly (GO:0031581) | 2.85860458 |
79 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.85707020 |
80 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.85550184 |
81 | cell migration in hindbrain (GO:0021535) | 2.85482332 |
82 | response to histamine (GO:0034776) | 2.83650047 |
83 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.83366283 |
84 | positive regulation of synapse maturation (GO:0090129) | 2.83217624 |
85 | positive regulation of dendritic spine development (GO:0060999) | 2.80514753 |
86 | regulation of neurotransmitter transport (GO:0051588) | 2.80220025 |
87 | behavioral defense response (GO:0002209) | 2.79570977 |
88 | behavioral fear response (GO:0001662) | 2.79570977 |
89 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.77250417 |
90 | positive regulation of neurotransmitter transport (GO:0051590) | 2.77218913 |
91 | regulation of synaptic transmission, GABAergic (GO:0032228) | 2.74962033 |
92 | mechanosensory behavior (GO:0007638) | 2.74550544 |
93 | desmosome organization (GO:0002934) | 2.74415141 |
94 | central nervous system neuron axonogenesis (GO:0021955) | 2.72022608 |
95 | dendritic spine organization (GO:0097061) | 2.70783541 |
96 | innervation (GO:0060384) | 2.70052493 |
97 | vesicle transport along microtubule (GO:0047496) | 2.69684272 |
98 | regulation of neurotransmitter levels (GO:0001505) | 2.69269319 |
99 | positive regulation of synapse assembly (GO:0051965) | 2.69054045 |
100 | fear response (GO:0042596) | 2.68496200 |
101 | L-amino acid import (GO:0043092) | 2.68241300 |
102 | synapse organization (GO:0050808) | 2.67996571 |
103 | positive regulation of synaptic transmission (GO:0050806) | 2.67564388 |
104 | regulation of respiratory system process (GO:0044065) | 2.65593044 |
105 | regulation of synaptic transmission (GO:0050804) | 2.65227378 |
106 | neuronal ion channel clustering (GO:0045161) | 2.64183597 |
107 | adult walking behavior (GO:0007628) | 2.63091509 |
108 | dendrite development (GO:0016358) | 2.61734973 |
109 | apical protein localization (GO:0045176) | 2.59618168 |
110 | sodium ion export (GO:0071436) | 2.55556873 |
111 | axon extension involved in axon guidance (GO:0048846) | 2.54158617 |
112 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.54158617 |
113 | axon extension (GO:0048675) | 2.53342693 |
114 | urinary tract smooth muscle contraction (GO:0014848) | 2.45482401 |
115 | pericardium development (GO:0060039) | 2.42561569 |
116 | fibroblast migration (GO:0010761) | 2.41273792 |
117 | positive regulation of action potential (GO:0045760) | 2.39913532 |
118 | neuron projection extension (GO:1990138) | 2.39441997 |
119 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.39421418 |
120 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.35270008 |
121 | positive regulation of dendrite morphogenesis (GO:0050775) | 2.34983342 |
122 | negative chemotaxis (GO:0050919) | 2.34599457 |
123 | cranial nerve morphogenesis (GO:0021602) | 2.34387230 |
124 | ganglion development (GO:0061548) | 2.33389235 |
125 | membrane assembly (GO:0071709) | 2.31285018 |
126 | embryonic foregut morphogenesis (GO:0048617) | 2.28323865 |
127 | cranial nerve structural organization (GO:0021604) | 2.27923190 |
128 | positive regulation of axon extension (GO:0045773) | 2.27281692 |
129 | myelination in peripheral nervous system (GO:0022011) | 2.26907226 |
130 | peripheral nervous system axon ensheathment (GO:0032292) | 2.26907226 |
131 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.24723381 |
132 | cell communication involved in cardiac conduction (GO:0086065) | 2.21659952 |
133 | anatomical structure arrangement (GO:0048532) | 2.21569001 |
134 | artery development (GO:0060840) | 2.20764299 |
135 | establishment of nucleus localization (GO:0040023) | 2.20682757 |
136 | asymmetric protein localization (GO:0008105) | 2.20646153 |
137 | sympathetic nervous system development (GO:0048485) | 2.19912803 |
138 | regulation of synapse assembly (GO:0051963) | 2.17498631 |
139 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.17025002 |
140 | lymphangiogenesis (GO:0001946) | 2.16971487 |
141 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.16194211 |
142 | facial nerve structural organization (GO:0021612) | 2.15853289 |
143 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.12977972 |
144 | endocardial cushion development (GO:0003197) | 2.12294863 |
145 | regulation of axon extension (GO:0030516) | 2.10949882 |
146 | organelle transport along microtubule (GO:0072384) | 2.09875630 |
147 | dermatan sulfate biosynthetic process (GO:0030208) | 2.09550561 |
148 | cell communication by electrical coupling (GO:0010644) | 2.08115003 |
149 | smooth muscle tissue development (GO:0048745) | 2.07872163 |
150 | negative regulation of axon extension (GO:0030517) | 2.06813547 |
151 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.06640256 |
152 | negative regulation of protein localization to cell surface (GO:2000009) | 2.06346592 |
153 | positive regulation of dendrite development (GO:1900006) | 2.04088764 |
154 | cell adhesion mediated by integrin (GO:0033627) | 2.03910484 |
155 | developmental cell growth (GO:0048588) | 2.03116049 |
156 | semaphorin-plexin signaling pathway (GO:0071526) | 2.02753859 |
157 | limb development (GO:0060173) | 2.02683436 |
158 | appendage development (GO:0048736) | 2.02683436 |
159 | camera-type eye morphogenesis (GO:0048593) | 2.02408887 |
160 | negative regulation of dendrite development (GO:2000171) | 2.02218025 |
161 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 2.00754977 |
162 | pyrimidine nucleobase catabolic process (GO:0006208) | 1.98975982 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.51534067 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.86793110 |
3 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.92172624 |
4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.90551887 |
5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.78821806 |
6 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.52372209 |
7 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.52372209 |
8 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.49706340 |
9 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.45015472 |
10 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.40244732 |
11 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.38533703 |
12 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.34718543 |
13 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.27703968 |
14 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.23589026 |
15 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.23458905 |
16 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.20660849 |
17 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.19073893 |
18 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.18162520 |
19 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.04809952 |
20 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.03692512 |
21 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.03522646 |
22 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.02020621 |
23 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.00922932 |
24 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.00309605 |
25 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.92782622 |
26 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.90148024 |
27 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.88255433 |
28 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.79762747 |
29 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.76074855 |
30 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.75035014 |
31 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.72563194 |
32 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.71858110 |
33 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.70991760 |
34 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.69915270 |
35 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.62049932 |
36 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.61742908 |
37 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.61097759 |
38 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.60355670 |
39 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.60203577 |
40 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.56947737 |
41 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.54805220 |
42 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.51433675 |
43 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.49735487 |
44 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.48886878 |
45 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.47992482 |
46 | CJUN_26792858_Chip-Seq_BT549_Human | 1.47712270 |
47 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.47596697 |
48 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.47387019 |
49 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.46896983 |
50 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.46540975 |
51 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.45793307 |
52 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.45317361 |
53 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.44581983 |
54 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.42715084 |
55 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.40472687 |
56 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.39106513 |
57 | * CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.37845130 |
58 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.37477317 |
59 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.37087542 |
60 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.36950826 |
61 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.36348902 |
62 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.35845461 |
63 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.35072593 |
64 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.35009057 |
65 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.34793110 |
66 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.34032884 |
67 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.31862060 |
68 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.31137872 |
69 | * FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.30054032 |
70 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.29992227 |
71 | AR_25329375_ChIP-Seq_VCAP_Human | 1.29838030 |
72 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.29509140 |
73 | TP53_16413492_ChIP-PET_HCT116_Human | 1.29211666 |
74 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.26481145 |
75 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.23090707 |
76 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.22588334 |
77 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.21273784 |
78 | * RNF2_27304074_Chip-Seq_NSC_Mouse | 1.21138009 |
79 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.20552657 |
80 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.19067125 |
81 | FUS_26573619_Chip-Seq_HEK293_Human | 1.17714398 |
82 | * NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.16868126 |
83 | * NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.16868126 |
84 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.16164083 |
85 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.16034669 |
86 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.15876483 |
87 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.14463537 |
88 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.14413862 |
89 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.13971015 |
90 | AR_19668381_ChIP-Seq_PC3_Human | 1.13763623 |
91 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.13261435 |
92 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.13143465 |
93 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.12558058 |
94 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.12113739 |
95 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.10622113 |
96 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.10493618 |
97 | * BRD4_25478319_ChIP-Seq_HGPS_Human | 1.10335304 |
98 | * STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.09240923 |
99 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.08862268 |
100 | * TP53_18474530_ChIP-ChIP_U2OS_Human | 1.08446984 |
101 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.08018025 |
102 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.07560598 |
103 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07560598 |
104 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.06033334 |
105 | * YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.05665405 |
106 | RXR_22108803_ChIP-Seq_LS180_Human | 1.05570841 |
107 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.05514350 |
108 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.05268215 |
109 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.05054115 |
110 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.04742455 |
111 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03308662 |
112 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.01433743 |
113 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.00840382 |
114 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.98945227 |
115 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.98629495 |
116 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.95869536 |
117 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.95110187 |
118 | * SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.92810718 |
119 | VDR_22108803_ChIP-Seq_LS180_Human | 0.92001084 |
120 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.90356491 |
121 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.89932562 |
122 | JUN_21703547_ChIP-Seq_K562_Human | 0.88409547 |
123 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.88160248 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.78140728 |
2 | MP0003880_abnormal_central_pattern | 4.87182210 |
3 | MP0003635_abnormal_synaptic_transmissio | 3.89990520 |
4 | MP0004270_analgesia | 3.80848234 |
5 | MP0009745_abnormal_behavioral_response | 3.18305597 |
6 | MP0002063_abnormal_learning/memory/cond | 3.15820788 |
7 | MP0002064_seizures | 2.97887310 |
8 | MP0001968_abnormal_touch/_nociception | 2.93024532 |
9 | MP0009046_muscle_twitch | 2.77966042 |
10 | MP0002572_abnormal_emotion/affect_behav | 2.74032601 |
11 | MP0005423_abnormal_somatic_nervous | 2.73660255 |
12 | MP0001486_abnormal_startle_reflex | 2.64631624 |
13 | MP0002734_abnormal_mechanical_nocicepti | 2.57764149 |
14 | MP0002272_abnormal_nervous_system | 2.39732452 |
15 | MP0002736_abnormal_nociception_after | 2.22310324 |
16 | MP0002735_abnormal_chemical_nociception | 2.21301081 |
17 | MP0000778_abnormal_nervous_system | 2.16762402 |
18 | MP0002822_catalepsy | 2.15055837 |
19 | MP0001501_abnormal_sleep_pattern | 2.11231507 |
20 | MP0001440_abnormal_grooming_behavior | 2.04782907 |
21 | MP0002067_abnormal_sensory_capabilities | 1.97204970 |
22 | MP0002733_abnormal_thermal_nociception | 1.91216198 |
23 | MP0002557_abnormal_social/conspecific_i | 1.90153526 |
24 | MP0000579_abnormal_nail_morphology | 1.89370049 |
25 | MP0009780_abnormal_chondrocyte_physiolo | 1.88645465 |
26 | MP0001970_abnormal_pain_threshold | 1.88464320 |
27 | MP0002184_abnormal_innervation | 1.86972048 |
28 | MP0003787_abnormal_imprinting | 1.86184652 |
29 | MP0000534_abnormal_ureter_morphology | 1.80930771 |
30 | MP0000383_abnormal_hair_follicle | 1.79970214 |
31 | MP0000569_abnormal_digit_pigmentation | 1.77725667 |
32 | MP0001984_abnormal_olfaction | 1.76248129 |
33 | MP0001188_hyperpigmentation | 1.73277623 |
34 | MP0005646_abnormal_pituitary_gland | 1.68310451 |
35 | MP0006276_abnormal_autonomic_nervous | 1.63952291 |
36 | MP0005645_abnormal_hypothalamus_physiol | 1.61685761 |
37 | MP0004924_abnormal_behavior | 1.61502813 |
38 | MP0005386_behavior/neurological_phenoty | 1.61502813 |
39 | MP0010678_abnormal_skin_adnexa | 1.61395584 |
40 | MP0004811_abnormal_neuron_physiology | 1.60611538 |
41 | MP0004858_abnormal_nervous_system | 1.59796554 |
42 | MP0008569_lethality_at_weaning | 1.58266580 |
43 | MP0003942_abnormal_urinary_system | 1.56820630 |
44 | MP0004272_abnormal_basement_membrane | 1.53337657 |
45 | MP0003879_abnormal_hair_cell | 1.51816515 |
46 | MP0008438_abnormal_cutaneous_collagen | 1.50454704 |
47 | MP0005275_abnormal_skin_tensile | 1.47754660 |
48 | MP0000955_abnormal_spinal_cord | 1.44745343 |
49 | MP0004885_abnormal_endolymph | 1.44383165 |
50 | MP0000427_abnormal_hair_cycle | 1.44106292 |
51 | MP0002882_abnormal_neuron_morphology | 1.43551475 |
52 | MP0003122_maternal_imprinting | 1.42596504 |
53 | MP0005503_abnormal_tendon_morphology | 1.40415538 |
54 | MP0003705_abnormal_hypodermis_morpholog | 1.40016662 |
55 | MP0002909_abnormal_adrenal_gland | 1.35212075 |
56 | MP0000537_abnormal_urethra_morphology | 1.33283512 |
57 | MP0002066_abnormal_motor_capabilities/c | 1.32438257 |
58 | MP0003329_amyloid_beta_deposits | 1.30903833 |
59 | MP0004742_abnormal_vestibular_system | 1.28765906 |
60 | MP0004233_abnormal_muscle_weight | 1.28160263 |
61 | MP0005187_abnormal_penis_morphology | 1.26981294 |
62 | MP0005409_darkened_coat_color | 1.26804068 |
63 | MP0003633_abnormal_nervous_system | 1.25498139 |
64 | MP0001502_abnormal_circadian_rhythm | 1.23440453 |
65 | MP0005248_abnormal_Harderian_gland | 1.22735016 |
66 | MP0000538_abnormal_urinary_bladder | 1.21388695 |
67 | MP0004142_abnormal_muscle_tone | 1.18758673 |
68 | MP0000462_abnormal_digestive_system | 1.17047215 |
69 | MP0001529_abnormal_vocalization | 1.16548406 |
70 | MP0005257_abnormal_intraocular_pressure | 1.14552179 |
71 | MP0004145_abnormal_muscle_electrophysio | 1.14256731 |
72 | MP0002152_abnormal_brain_morphology | 1.13708066 |
73 | MP0001905_abnormal_dopamine_level | 1.13673899 |
74 | MP0003755_abnormal_palate_morphology | 1.13362851 |
75 | MP0003283_abnormal_digestive_organ | 1.11721616 |
76 | MP0001958_emphysema | 1.10196838 |
77 | MP0009250_abnormal_appendicular_skeleto | 1.09681169 |
78 | MP0009384_cardiac_valve_regurgitation | 1.05370338 |
79 | MP0003935_abnormal_craniofacial_develop | 1.05315200 |
80 | MP0003937_abnormal_limbs/digits/tail_de | 1.04618093 |
81 | MP0003631_nervous_system_phenotype | 1.04145669 |
82 | MP0000631_abnormal_neuroendocrine_gland | 1.02288050 |
83 | MP0002751_abnormal_autonomic_nervous | 1.01541661 |
84 | MP0001963_abnormal_hearing_physiology | 1.01235815 |
85 | MP0010386_abnormal_urinary_bladder | 0.99535350 |
86 | MP0002896_abnormal_bone_mineralization | 0.98338185 |
87 | MP0000751_myopathy | 0.97516501 |
88 | MP0005076_abnormal_cell_differentiation | 0.95852978 |
89 | MP0000762_abnormal_tongue_morphology | 0.95783406 |
90 | MP0001177_atelectasis | 0.95498257 |
91 | MP0002229_neurodegeneration | 0.94644516 |
92 | MP0002234_abnormal_pharynx_morphology | 0.93217828 |
93 | MP0003385_abnormal_body_wall | 0.93159466 |
94 | MP0001879_abnormal_lymphatic_vessel | 0.91823133 |
95 | MP0009053_abnormal_anal_canal | 0.91636368 |
96 | MP0000920_abnormal_myelination | 0.91129274 |
97 | MP0003690_abnormal_glial_cell | 0.90614197 |
98 | MP0005551_abnormal_eye_electrophysiolog | 0.90491460 |
99 | MP0003634_abnormal_glial_cell | 0.90396371 |
100 | MP0010368_abnormal_lymphatic_system | 0.88882808 |
101 | MP0003950_abnormal_plasma_membrane | 0.88749008 |
102 | MP0003890_abnormal_embryonic-extraembry | 0.88358379 |
103 | MP0003091_abnormal_cell_migration | 0.87659691 |
104 | MP0002069_abnormal_eating/drinking_beha | 0.87510948 |
105 | MP0004085_abnormal_heartbeat | 0.86572111 |
106 | MP0002752_abnormal_somatic_nervous | 0.86172475 |
107 | MP0002116_abnormal_craniofacial_bone | 0.85983797 |
108 | MP0003115_abnormal_respiratory_system | 0.85685347 |
109 | MP0004134_abnormal_chest_morphology | 0.84817673 |
110 | MP0002108_abnormal_muscle_morphology | 0.83418690 |
111 | MP0001299_abnormal_eye_distance/ | 0.83209322 |
112 | MP0000428_abnormal_craniofacial_morphol | 0.83164072 |
113 | MP0000013_abnormal_adipose_tissue | 0.82072218 |
114 | MP0001485_abnormal_pinna_reflex | 0.81465454 |
115 | MP0005499_abnormal_olfactory_system | 0.79889508 |
116 | MP0005394_taste/olfaction_phenotype | 0.79889508 |
117 | MP0000003_abnormal_adipose_tissue | 0.79372183 |
118 | MP0004484_altered_response_of | 0.78896388 |
119 | MP0000733_abnormal_muscle_development | 0.76013729 |
120 | MP0002081_perinatal_lethality | 0.75723878 |
121 | MP0008874_decreased_physiological_sensi | 0.75426538 |
122 | MP0000432_abnormal_head_morphology | 0.73927954 |
123 | MP0001664_abnormal_digestion | 0.73533192 |
124 | MP0005171_absent_coat_pigmentation | 0.73327002 |
125 | MP0002249_abnormal_larynx_morphology | 0.73294081 |
126 | MP0000647_abnormal_sebaceous_gland | 0.73054159 |
127 | MP0008872_abnormal_physiological_respon | 0.72457477 |
128 | MP0002102_abnormal_ear_morphology | 0.70879435 |
129 | MP0003045_fibrosis | 0.70450753 |
130 | MP0002090_abnormal_vision | 0.68982232 |
131 | MP0003632_abnormal_nervous_system | 0.68386799 |
132 | MP0002638_abnormal_pupillary_reflex | 0.68121243 |
133 | MP0003172_abnormal_lysosome_physiology | 0.67971929 |
134 | MP0000026_abnormal_inner_ear | 0.66384664 |
135 | MP0003861_abnormal_nervous_system | 0.65447953 |
136 | MP0004510_myositis | 0.64716594 |
137 | MP0001943_abnormal_respiration | 0.64697923 |
138 | MP0008961_abnormal_basal_metabolism | 0.63867799 |
139 | MP0000015_abnormal_ear_pigmentation | 0.63226822 |
140 | MP0003121_genomic_imprinting | 0.62736753 |
141 | MP0005623_abnormal_meninges_morphology | 0.62614513 |
142 | MP0003137_abnormal_impulse_conducting | 0.61836803 |
143 | MP0005535_abnormal_body_temperature | 0.60204138 |
144 | MP0002082_postnatal_lethality | 0.54153698 |
145 | MP0010770_preweaning_lethality | 0.54153698 |
146 | MP0002876_abnormal_thyroid_physiology | 0.53657183 |
147 | MP0004215_abnormal_myocardial_fiber | 0.52762880 |
148 | MP0010769_abnormal_survival | 0.52200241 |
149 | MP0003075_altered_response_to | 0.52081953 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 7.11566779 |
2 | Focal seizures (HP:0007359) | 5.38615175 |
3 | Myokymia (HP:0002411) | 5.30597482 |
4 | Epileptic encephalopathy (HP:0200134) | 4.68724147 |
5 | Febrile seizures (HP:0002373) | 4.33032506 |
6 | Atonic seizures (HP:0010819) | 4.13484234 |
7 | Visual hallucinations (HP:0002367) | 3.98569538 |
8 | Progressive cerebellar ataxia (HP:0002073) | 3.96206451 |
9 | Broad-based gait (HP:0002136) | 3.76707845 |
10 | Hyperventilation (HP:0002883) | 3.61309539 |
11 | Absence seizures (HP:0002121) | 3.58248488 |
12 | Generalized tonic-clonic seizures (HP:0002069) | 3.48784065 |
13 | Action tremor (HP:0002345) | 3.40071898 |
14 | Supranuclear gaze palsy (HP:0000605) | 3.38834696 |
15 | Dialeptic seizures (HP:0011146) | 3.37621516 |
16 | Mutism (HP:0002300) | 3.33613416 |
17 | Drooling (HP:0002307) | 3.20665775 |
18 | Excessive salivation (HP:0003781) | 3.20665775 |
19 | Gaze-evoked nystagmus (HP:0000640) | 3.16022391 |
20 | Truncal ataxia (HP:0002078) | 2.97774945 |
21 | Genetic anticipation (HP:0003743) | 2.94233592 |
22 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.92535193 |
23 | Ankle clonus (HP:0011448) | 2.84926346 |
24 | Poor eye contact (HP:0000817) | 2.80420055 |
25 | Amblyopia (HP:0000646) | 2.77666378 |
26 | Absent frontal sinuses (HP:0002688) | 2.74159651 |
27 | Dysdiadochokinesis (HP:0002075) | 2.70402053 |
28 | Absent speech (HP:0001344) | 2.67020566 |
29 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.65406491 |
30 | Abnormal eating behavior (HP:0100738) | 2.65351680 |
31 | Neurofibrillary tangles (HP:0002185) | 2.62582431 |
32 | Dysmetria (HP:0001310) | 2.58274082 |
33 | Postural instability (HP:0002172) | 2.56357933 |
34 | Depression (HP:0000716) | 2.52664822 |
35 | Impaired social interactions (HP:0000735) | 2.48914713 |
36 | Abnormal social behavior (HP:0012433) | 2.48914713 |
37 | Termporal pattern (HP:0011008) | 2.48512665 |
38 | Insidious onset (HP:0003587) | 2.48512665 |
39 | Atrophic scars (HP:0001075) | 2.48073828 |
40 | Abnormality of the corticospinal tract (HP:0002492) | 2.44934378 |
41 | Hemiparesis (HP:0001269) | 2.44817410 |
42 | Exotropia (HP:0000577) | 2.44634142 |
43 | Polyphagia (HP:0002591) | 2.43433043 |
44 | Cerebral inclusion bodies (HP:0100314) | 2.42800575 |
45 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 2.40520559 |
46 | Obstructive sleep apnea (HP:0002870) | 2.40098044 |
47 | Macroorchidism (HP:0000053) | 2.38286167 |
48 | Anxiety (HP:0000739) | 2.38142585 |
49 | Papilledema (HP:0001085) | 2.37286036 |
50 | Diplopia (HP:0000651) | 2.36116120 |
51 | Abnormality of binocular vision (HP:0011514) | 2.36116120 |
52 | Stereotypic behavior (HP:0000733) | 2.34617219 |
53 | Limb dystonia (HP:0002451) | 2.30833757 |
54 | Urinary urgency (HP:0000012) | 2.27391623 |
55 | Scanning speech (HP:0002168) | 2.26431903 |
56 | Inappropriate behavior (HP:0000719) | 2.25205511 |
57 | Epileptiform EEG discharges (HP:0011182) | 2.24230034 |
58 | Progressive inability to walk (HP:0002505) | 2.24054638 |
59 | Abnormality of salivation (HP:0100755) | 2.22811749 |
60 | Inability to walk (HP:0002540) | 2.22311424 |
61 | Heterotopia (HP:0002282) | 2.20236151 |
62 | Impaired smooth pursuit (HP:0007772) | 2.19523410 |
63 | Fetal akinesia sequence (HP:0001989) | 2.15110558 |
64 | Blue irides (HP:0000635) | 2.13394514 |
65 | Broad face (HP:0000283) | 2.12340227 |
66 | Widely spaced teeth (HP:0000687) | 2.11744365 |
67 | Torticollis (HP:0000473) | 2.11212278 |
68 | Spastic gait (HP:0002064) | 2.11075382 |
69 | Vascular tortuosity (HP:0004948) | 2.10434840 |
70 | Papillary thyroid carcinoma (HP:0002895) | 2.10406191 |
71 | EEG with generalized epileptiform discharges (HP:0011198) | 2.10072173 |
72 | Protruding tongue (HP:0010808) | 2.03267529 |
73 | Abnormality of the ischium (HP:0003174) | 2.02581623 |
74 | Aqueductal stenosis (HP:0002410) | 2.02423024 |
75 | Hemiplegia (HP:0002301) | 2.01798823 |
76 | Sleep apnea (HP:0010535) | 1.99589897 |
77 | Bradykinesia (HP:0002067) | 1.98871022 |
78 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.98583694 |
79 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.98583694 |
80 | Agitation (HP:0000713) | 1.97530517 |
81 | Abnormality of the frontal sinuses (HP:0002687) | 1.97066773 |
82 | Absent/shortened dynein arms (HP:0200106) | 1.95847639 |
83 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.95847639 |
84 | Hypsarrhythmia (HP:0002521) | 1.92561173 |
85 | Lower limb muscle weakness (HP:0007340) | 1.92472432 |
86 | Gait imbalance (HP:0002141) | 1.90746924 |
87 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 1.90508663 |
88 | Neuronal loss in central nervous system (HP:0002529) | 1.90340113 |
89 | Open mouth (HP:0000194) | 1.88316405 |
90 | Focal dystonia (HP:0004373) | 1.88007570 |
91 | Short nail (HP:0001799) | 1.86619446 |
92 | Shawl scrotum (HP:0000049) | 1.85574786 |
93 | Morphological abnormality of the middle ear (HP:0008609) | 1.85187830 |
94 | Megalencephaly (HP:0001355) | 1.85077584 |
95 | Impaired vibratory sensation (HP:0002495) | 1.84615403 |
96 | Generalized hypopigmentation of hair (HP:0011358) | 1.84084394 |
97 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.83206863 |
98 | Clumsiness (HP:0002312) | 1.83110122 |
99 | Lower limb amyotrophy (HP:0007210) | 1.81203704 |
100 | Shallow orbits (HP:0000586) | 1.79397254 |
101 | Generalized myoclonic seizures (HP:0002123) | 1.78830681 |
102 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.78219111 |
103 | Aplasia of the phalanges of the hand (HP:0009802) | 1.78219111 |
104 | Aplasia involving bones of the extremities (HP:0009825) | 1.78219111 |
105 | Intention tremor (HP:0002080) | 1.78153426 |
106 | Hypoplastic ischia (HP:0003175) | 1.76878158 |
107 | Lower limb asymmetry (HP:0100559) | 1.75930463 |
108 | Specific learning disability (HP:0001328) | 1.75921790 |
109 | Gastroesophageal reflux (HP:0002020) | 1.75433968 |
110 | Abnormal hair whorl (HP:0010721) | 1.74933513 |
111 | Thickened helices (HP:0000391) | 1.74665029 |
112 | Abnormal ciliary motility (HP:0012262) | 1.74609007 |
113 | Increased number of teeth (HP:0011069) | 1.74574823 |
114 | Dysmetric saccades (HP:0000641) | 1.73396458 |
115 | Status epilepticus (HP:0002133) | 1.73146506 |
116 | Hypoventilation (HP:0002791) | 1.71350412 |
117 | Arterial tortuosity (HP:0005116) | 1.71063364 |
118 | Retinal dysplasia (HP:0007973) | 1.70707829 |
119 | Bronchomalacia (HP:0002780) | 1.69989610 |
120 | Microglossia (HP:0000171) | 1.69412398 |
121 | Overgrowth (HP:0001548) | 1.66599203 |
122 | Aortic dissection (HP:0002647) | 1.61808859 |
123 | Tented upper lip vermilion (HP:0010804) | 1.60357501 |
124 | Aortic aneurysm (HP:0004942) | 1.60112363 |
125 | Tibial bowing (HP:0002982) | 1.59043495 |
126 | Laryngomalacia (HP:0001601) | 1.58565038 |
127 | Pulmonic stenosis (HP:0001642) | 1.57652909 |
128 | Hypoplastic nipples (HP:0002557) | 1.56473346 |
129 | Buphthalmos (HP:0000557) | 1.56446588 |
130 | Cubitus valgus (HP:0002967) | 1.56136934 |
131 | Spondylolisthesis (HP:0003302) | 1.55153027 |
132 | Hypoplastic labia majora (HP:0000059) | 1.54671909 |
133 | Bell-shaped thorax (HP:0001591) | 1.54563858 |
134 | Hypopigmentation of the fundus (HP:0007894) | 1.52198283 |
135 | Midline defect of the nose (HP:0004122) | 1.51675405 |
136 | Hyperacusis (HP:0010780) | 1.50527677 |
137 | Abnormality of the nasal septum (HP:0000419) | 1.50364447 |
138 | Milia (HP:0001056) | 1.50303956 |
139 | Abnormality of the astrocytes (HP:0100707) | 1.49781907 |
140 | Astrocytoma (HP:0009592) | 1.49781907 |
141 | Ulnar bowing (HP:0003031) | 1.49591416 |
142 | Tracheomalacia (HP:0002779) | 1.49266942 |
143 | Cutaneous finger syndactyly (HP:0010554) | 1.49026141 |
144 | Abnormality of the epiphyses of the phalanges of the hand (HP:0005920) | 1.47589064 |
145 | Abnormality of the sella turcica (HP:0002679) | 1.47579962 |
146 | Abnormality of the labia majora (HP:0012881) | 1.47553921 |
147 | Narrow palate (HP:0000189) | 1.46304455 |
148 | Asymmetry of the thorax (HP:0001555) | 1.45523303 |
149 | Wormian bones (HP:0002645) | 1.45238373 |
150 | Round face (HP:0000311) | 1.45202045 |
151 | Germ cell neoplasia (HP:0100728) | 1.45141787 |
152 | Abnormality of dentin (HP:0010299) | 1.44488293 |
153 | Long toe (HP:0010511) | 1.43923103 |
154 | Neoplasm of the heart (HP:0100544) | 1.43602915 |
155 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.43442750 |
156 | Short 4th metacarpal (HP:0010044) | 1.43442750 |
157 | Vertebral arch anomaly (HP:0008438) | 1.43371853 |
158 | Protrusio acetabuli (HP:0003179) | 1.42808124 |
159 | Relative macrocephaly (HP:0004482) | 1.42773841 |
160 | Coronal craniosynostosis (HP:0004440) | 1.42466361 |
161 | Bradycardia (HP:0001662) | 1.42400352 |
162 | Limited hip movement (HP:0008800) | 1.42233589 |
163 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.42068334 |
164 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.41300176 |
165 | Aplasia of the musculature (HP:0100854) | 1.41282040 |
166 | Short chin (HP:0000331) | 1.41216793 |
167 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.41183941 |
168 | Cerebellar dysplasia (HP:0007033) | 1.41069751 |
169 | Complete atrioventricular canal defect (HP:0001674) | 1.40563798 |
170 | Abnormality of the 2nd finger (HP:0004100) | 1.38777782 |
171 | Septate vagina (HP:0001153) | 1.37862268 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NTRK3 | 4.04289127 |
2 | EPHA4 | 3.99539181 |
3 | MARK1 | 3.62376487 |
4 | FRK | 3.27292620 |
5 | MAP3K9 | 3.24567812 |
6 | CASK | 2.98362170 |
7 | MAP3K4 | 2.97585257 |
8 | MAP2K7 | 2.72905310 |
9 | MINK1 | 2.27438360 |
10 | NTRK2 | 2.16965263 |
11 | RIPK4 | 2.13820549 |
12 | DAPK2 | 1.99685221 |
13 | TNIK | 1.91082307 |
14 | PIK3CA | 1.88940825 |
15 | MAPK13 | 1.87690929 |
16 | PNCK | 1.82389798 |
17 | PAK6 | 1.81101534 |
18 | MAP2K4 | 1.78876637 |
19 | PKN2 | 1.76207491 |
20 | SIK2 | 1.70740000 |
21 | MAP3K12 | 1.67455257 |
22 | PDGFRA | 1.60917817 |
23 | CDK12 | 1.60025688 |
24 | PTK2 | 1.56969135 |
25 | PLK2 | 1.50460962 |
26 | NTRK1 | 1.49361680 |
27 | CAMK1G | 1.46075141 |
28 | SIK1 | 1.43837876 |
29 | MET | 1.42693381 |
30 | CDK5 | 1.42401277 |
31 | KSR1 | 1.40445065 |
32 | CAMKK1 | 1.36774581 |
33 | LATS1 | 1.26608710 |
34 | KSR2 | 1.26411531 |
35 | EPHB2 | 1.24780798 |
36 | GRK5 | 1.21791979 |
37 | PRKD3 | 1.21552999 |
38 | OXSR1 | 1.15742640 |
39 | FES | 1.13170292 |
40 | BRD4 | 1.12954561 |
41 | GRK7 | 1.12699131 |
42 | CAMKK2 | 1.12533275 |
43 | PHKG2 | 1.09608124 |
44 | PHKG1 | 1.09608124 |
45 | CDK19 | 1.09579348 |
46 | SGK494 | 1.08696158 |
47 | SGK223 | 1.08696158 |
48 | RPS6KA2 | 1.08168978 |
49 | MTOR | 1.07942835 |
50 | DAPK1 | 1.07678492 |
51 | PDGFRB | 1.03313808 |
52 | SGK2 | 1.03125945 |
53 | CAMK2A | 1.02066765 |
54 | EPHA2 | 1.01625872 |
55 | UHMK1 | 0.99499236 |
56 | CAMK1 | 0.97080363 |
57 | BMPR2 | 0.95465954 |
58 | PRKCG | 0.94980148 |
59 | PRPF4B | 0.93403185 |
60 | MARK2 | 0.91547408 |
61 | MST1R | 0.90737042 |
62 | DDR2 | 0.90130992 |
63 | TRIB3 | 0.89676050 |
64 | STK38L | 0.88032871 |
65 | MAP3K7 | 0.86338960 |
66 | STK11 | 0.86333089 |
67 | STK38 | 0.86069997 |
68 | CAMK2B | 0.85677523 |
69 | CSNK1A1L | 0.85223317 |
70 | ICK | 0.84771220 |
71 | PINK1 | 0.83852431 |
72 | SIK3 | 0.83708705 |
73 | PRKD2 | 0.81176030 |
74 | CSNK1G2 | 0.79955155 |
75 | SGK1 | 0.78621445 |
76 | DYRK1A | 0.77564940 |
77 | MAP3K2 | 0.76530074 |
78 | ROCK1 | 0.76332275 |
79 | MAP3K13 | 0.75966605 |
80 | RET | 0.73887195 |
81 | MUSK | 0.73174128 |
82 | SGK3 | 0.73140507 |
83 | RIPK1 | 0.73138023 |
84 | PTK2B | 0.72971421 |
85 | CDK3 | 0.71583550 |
86 | STK39 | 0.71186522 |
87 | PRKCE | 0.70195097 |
88 | LATS2 | 0.69612267 |
89 | CDK18 | 0.69329410 |
90 | PKN1 | 0.69023259 |
91 | LMTK2 | 0.68679853 |
92 | WNK3 | 0.68173964 |
93 | TRPM7 | 0.68044474 |
94 | AKT3 | 0.67506492 |
95 | PAK3 | 0.65957635 |
96 | SCYL2 | 0.65949566 |
97 | CDK15 | 0.65696378 |
98 | WNK1 | 0.65305837 |
99 | CDK14 | 0.65026301 |
100 | TYRO3 | 0.62819938 |
101 | CAMK1D | 0.62668771 |
102 | BMPR1B | 0.61555073 |
103 | MAPK12 | 0.60839555 |
104 | FER | 0.59332904 |
105 | MAP2K1 | 0.58648399 |
106 | MYLK | 0.58181822 |
107 | CAMK4 | 0.57463453 |
108 | NEK6 | 0.57162562 |
109 | MAP3K6 | 0.56905138 |
110 | CDK11A | 0.56222913 |
111 | MAPK15 | 0.54999435 |
112 | FGR | 0.54238882 |
113 | FGFR2 | 0.53583758 |
114 | ROCK2 | 0.53493041 |
115 | PRKCH | 0.53332094 |
116 | CCNB1 | 0.52690395 |
117 | MAPKAPK3 | 0.52672087 |
118 | DMPK | 0.52479824 |
119 | PRKCZ | 0.52039188 |
120 | CAMK2G | 0.51124255 |
121 | TAOK1 | 0.50350142 |
122 | MELK | 0.50076588 |
123 | PDPK1 | 0.49789359 |
124 | CDC42BPA | 0.48781770 |
125 | EPHB1 | 0.47000930 |
126 | PDK1 | 0.46924587 |
127 | RPS6KB1 | 0.46685501 |
128 | FYN | 0.46291445 |
129 | ERBB3 | 0.46045248 |
130 | WNK4 | 0.44742065 |
131 | MAPK10 | 0.43620305 |
132 | RAF1 | 0.43602493 |
133 | MAPKAPK5 | 0.43497237 |
134 | RPS6KA3 | 0.42906500 |
135 | PRKAA1 | 0.42569344 |
136 | BCR | 0.42561048 |
137 | ARAF | 0.41748611 |
138 | CAMK2D | 0.41517803 |
139 | CSNK1D | 0.41150315 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.52052812 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.67080726 |
3 | Olfactory transduction_Homo sapiens_hsa04740 | 2.60395600 |
4 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.55904329 |
5 | Circadian entrainment_Homo sapiens_hsa04713 | 2.49071617 |
6 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.43758747 |
7 | GABAergic synapse_Homo sapiens_hsa04727 | 2.39944086 |
8 | Morphine addiction_Homo sapiens_hsa05032 | 2.37092445 |
9 | Long-term potentiation_Homo sapiens_hsa04720 | 2.35912139 |
10 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.23248049 |
11 | Salivary secretion_Homo sapiens_hsa04970 | 2.10560018 |
12 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.01867146 |
13 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.86315878 |
14 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.82693805 |
15 | Renin secretion_Homo sapiens_hsa04924 | 1.80467981 |
16 | Insulin secretion_Homo sapiens_hsa04911 | 1.80283184 |
17 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.78861779 |
18 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.76939445 |
19 | Taste transduction_Homo sapiens_hsa04742 | 1.75221517 |
20 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.68173005 |
21 | Long-term depression_Homo sapiens_hsa04730 | 1.68091855 |
22 | Cocaine addiction_Homo sapiens_hsa05030 | 1.62977568 |
23 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.61541162 |
24 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.55635150 |
25 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.50393182 |
26 | Axon guidance_Homo sapiens_hsa04360 | 1.47118694 |
27 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.42287417 |
28 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.41109757 |
29 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.38618621 |
30 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.34594058 |
31 | Gap junction_Homo sapiens_hsa04540 | 1.32930276 |
32 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.32642639 |
33 | Adherens junction_Homo sapiens_hsa04520 | 1.32171821 |
34 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.30469467 |
35 | Focal adhesion_Homo sapiens_hsa04510 | 1.28874051 |
36 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.26291520 |
37 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.26079920 |
38 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.25016124 |
39 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.22276508 |
40 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.15335779 |
41 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.13983310 |
42 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.13715449 |
43 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.12494301 |
44 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.10520584 |
45 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.10407734 |
46 | Tight junction_Homo sapiens_hsa04530 | 1.09684481 |
47 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.08731092 |
48 | Glioma_Homo sapiens_hsa05214 | 1.06728341 |
49 | Melanogenesis_Homo sapiens_hsa04916 | 1.06028402 |
50 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.00330539 |
51 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.96117149 |
52 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.95797156 |
53 | Phototransduction_Homo sapiens_hsa04744 | 0.94985334 |
54 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.94328665 |
55 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.94161730 |
56 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.93579409 |
57 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.92756625 |
58 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.91295361 |
59 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.90549081 |
60 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.86208899 |
61 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.85778325 |
62 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.84413491 |
63 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.83609335 |
64 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.81331748 |
65 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.80984154 |
66 | Lysine degradation_Homo sapiens_hsa00310 | 0.78812838 |
67 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.77719054 |
68 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.77658387 |
69 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.77502200 |
70 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.76582896 |
71 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.75903661 |
72 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.74841848 |
73 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.74190058 |
74 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.72551663 |
75 | Bile secretion_Homo sapiens_hsa04976 | 0.70152326 |
76 | Prostate cancer_Homo sapiens_hsa05215 | 0.70039513 |
77 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.68529500 |
78 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.68504558 |
79 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.68328494 |
80 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.67546846 |
81 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.66206725 |
82 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.65052147 |
83 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.64361273 |
84 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.64331669 |
85 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.63876235 |
86 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.63512887 |
87 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.63295968 |
88 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.61676725 |
89 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.60555148 |
90 | Amoebiasis_Homo sapiens_hsa05146 | 0.60518501 |
91 | Pathways in cancer_Homo sapiens_hsa05200 | 0.60127556 |
92 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.58823273 |
93 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.58231451 |
94 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.57400339 |
95 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.57374606 |
96 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.56590978 |
97 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.56513907 |
98 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.55745845 |
99 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.55647443 |
100 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.53668221 |
101 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.53228443 |
102 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.53050463 |
103 | Endometrial cancer_Homo sapiens_hsa05213 | 0.51315984 |
104 | Circadian rhythm_Homo sapiens_hsa04710 | 0.50431647 |
105 | Prion diseases_Homo sapiens_hsa05020 | 0.50418778 |
106 | Endocytosis_Homo sapiens_hsa04144 | 0.50342299 |
107 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.47467394 |
108 | Colorectal cancer_Homo sapiens_hsa05210 | 0.47204195 |
109 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.45913945 |
110 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.45871978 |
111 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.45373207 |
112 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.43839928 |
113 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.43163978 |
114 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.42293656 |
115 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.40914612 |
116 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.40401139 |
117 | Alcoholism_Homo sapiens_hsa05034 | 0.39644713 |
118 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.39249213 |
119 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.39066328 |
120 | Platelet activation_Homo sapiens_hsa04611 | 0.38278921 |
121 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.37549663 |
122 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.37233346 |
123 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.35416322 |
124 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.34134444 |
125 | Melanoma_Homo sapiens_hsa05218 | 0.31549906 |