TARSL2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1behavioral response to nicotine (GO:0035095)4.67975948
2mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.57011272
3mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.31342057
4deoxyribonucleoside diphosphate metabolic process (GO:0009186)4.15761083
5actin-myosin filament sliding (GO:0033275)4.14961588
6muscle filament sliding (GO:0030049)4.14961588
7energy coupled proton transport, down electrochemical gradient (GO:0015985)3.95395407
8ATP synthesis coupled proton transport (GO:0015986)3.95395407
9interkinetic nuclear migration (GO:0022027)3.94180675
10L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.93914399
11respiratory electron transport chain (GO:0022904)3.87071222
12regulation of relaxation of muscle (GO:1901077)3.80159660
13deoxyribonucleotide biosynthetic process (GO:0009263)3.78792071
14electron transport chain (GO:0022900)3.74811115
15proteasome assembly (GO:0043248)3.68766415
16cellular ketone body metabolic process (GO:0046950)3.67770912
17neuronal action potential propagation (GO:0019227)3.55669679
18gamma-aminobutyric acid transport (GO:0015812)3.50677218
19regulation of mitochondrial translation (GO:0070129)3.49735359
20amino acid salvage (GO:0043102)3.48869337
21L-methionine salvage (GO:0071267)3.48869337
22L-methionine biosynthetic process (GO:0071265)3.48869337
23negative regulation of cytosolic calcium ion concentration (GO:0051481)3.47001717
24regulation of cell communication by electrical coupling (GO:0010649)3.43194917
25termination of RNA polymerase III transcription (GO:0006386)3.42906153
26transcription elongation from RNA polymerase III promoter (GO:0006385)3.42906153
27protein-cofactor linkage (GO:0018065)3.40608510
28regulation of skeletal muscle contraction (GO:0014819)3.38758342
29axon ensheathment in central nervous system (GO:0032291)3.38066100
30central nervous system myelination (GO:0022010)3.38066100
31actin-mediated cell contraction (GO:0070252)3.36913042
32mitochondrial DNA replication (GO:0006264)3.34704658
33protein polyglutamylation (GO:0018095)3.32490859
34DNA replication checkpoint (GO:0000076)3.29407160
35chaperone-mediated protein transport (GO:0072321)3.27975498
36pyrimidine nucleobase catabolic process (GO:0006208)3.27273455
37regulation of nuclear cell cycle DNA replication (GO:0033262)3.21228738
38sensory perception of smell (GO:0007608)3.18774846
39ketone body metabolic process (GO:1902224)3.14920776
40detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.12109918
41deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.10755038
42CENP-A containing nucleosome assembly (GO:0034080)3.10721816
43positive regulation of phosphoprotein phosphatase activity (GO:0032516)3.07574732
44neurotransmitter-gated ion channel clustering (GO:0072578)3.06172596
45telomere maintenance via semi-conservative replication (GO:0032201)3.05998378
46positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.05905499
47G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.04056276
48chromatin remodeling at centromere (GO:0031055)3.03430605
49membrane depolarization during action potential (GO:0086010)3.00847383
50retinal cone cell development (GO:0046549)2.97583474
51sarcomere organization (GO:0045214)2.96655433
52cell wall macromolecule catabolic process (GO:0016998)2.96581058
537-methylguanosine mRNA capping (GO:0006370)2.95781943
54presynaptic membrane assembly (GO:0097105)2.93238091
55RNA capping (GO:0036260)2.93159010
567-methylguanosine RNA capping (GO:0009452)2.93159010
57myofibril assembly (GO:0030239)2.92892473
58long-chain fatty acid biosynthetic process (GO:0042759)2.92387751
59DNA deamination (GO:0045006)2.89712146
60centriole replication (GO:0007099)2.89336884
61positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.85041452
62rRNA modification (GO:0000154)2.84886565
63presynaptic membrane organization (GO:0097090)2.82556982
64regulation of cellular respiration (GO:0043457)2.82369049
65cyclic nucleotide catabolic process (GO:0009214)2.82314316
66nonmotile primary cilium assembly (GO:0035058)2.81524985
67glutamate receptor signaling pathway (GO:0007215)2.80250744
68neuron cell-cell adhesion (GO:0007158)2.79670662
69dendritic spine morphogenesis (GO:0060997)2.79225136
70vocalization behavior (GO:0071625)2.78608719
71sarcoplasmic reticulum calcium ion transport (GO:0070296)2.78540960
72negative regulation of translation, ncRNA-mediated (GO:0040033)2.78284687
73regulation of translation, ncRNA-mediated (GO:0045974)2.78284687
74negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.78284687
75negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254)2.77805639
76protein complex biogenesis (GO:0070271)2.77793949
77DNA-dependent DNA replication (GO:0006261)2.77776387
78cAMP catabolic process (GO:0006198)2.75571652
79ribosome assembly (GO:0042255)2.75140158
80striated muscle contraction (GO:0006941)2.74565756
81regulation of actin filament-based movement (GO:1903115)2.73434561
82quinone biosynthetic process (GO:1901663)2.73332118
83ubiquinone biosynthetic process (GO:0006744)2.73332118
84negative regulation of DNA-dependent DNA replication (GO:2000104)2.70467418
85regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.68620354
86negative regulation of synaptic transmission, GABAergic (GO:0032229)2.67099754
87regulation of hexokinase activity (GO:1903299)2.66605124
88regulation of glucokinase activity (GO:0033131)2.66605124
89telomere maintenance via recombination (GO:0000722)2.66454845
90regulation of membrane repolarization (GO:0060306)2.65429394
91protein import into peroxisome matrix (GO:0016558)2.65224640
92detection of calcium ion (GO:0005513)2.64918629
93protein localization to synapse (GO:0035418)2.64658344
94glycerophospholipid catabolic process (GO:0046475)2.64323622
95respiratory chain complex IV assembly (GO:0008535)2.64308581
96cell wall macromolecule metabolic process (GO:0044036)2.63259848
97ubiquinone metabolic process (GO:0006743)2.63259566
98mitochondrial respiratory chain complex I assembly (GO:0032981)2.62353986
99NADH dehydrogenase complex assembly (GO:0010257)2.62353986
100mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.62353986
101iron-sulfur cluster assembly (GO:0016226)2.61862498
102metallo-sulfur cluster assembly (GO:0031163)2.61862498
103nucleobase catabolic process (GO:0046113)2.61249419
104forebrain morphogenesis (GO:0048853)2.60361651
105postsynaptic membrane organization (GO:0001941)2.59113640
106negative regulation of response to food (GO:0032096)2.58887590
107negative regulation of appetite (GO:0032099)2.58887590
108methionine biosynthetic process (GO:0009086)2.57557821
109mitochondrial respiratory chain complex assembly (GO:0033108)2.56135897
110regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.55670748
111tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.55614218
112RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.55614218
113histone exchange (GO:0043486)2.55468097
114epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.55059767
115regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.54726734
116regulation of oxidative phosphorylation (GO:0002082)2.53384139
117synaptic transmission, cholinergic (GO:0007271)2.53151680
118otic vesicle formation (GO:0030916)2.53146265
119regulation of acyl-CoA biosynthetic process (GO:0050812)2.53144681
120DNA strand elongation involved in DNA replication (GO:0006271)2.52385611
121auditory receptor cell stereocilium organization (GO:0060088)2.52056787
122fucose catabolic process (GO:0019317)2.51512217
123L-fucose metabolic process (GO:0042354)2.51512217
124L-fucose catabolic process (GO:0042355)2.51512217
125neuronal action potential (GO:0019228)2.51343842
126protein K11-linked deubiquitination (GO:0035871)2.50152235
127neuromuscular synaptic transmission (GO:0007274)2.50121966
128response to pheromone (GO:0019236)2.49742151
129positive regulation of potassium ion transmembrane transport (GO:1901381)2.49734360
130cardiac myofibril assembly (GO:0055003)2.49230803
131response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.49063866
132cardiac muscle contraction (GO:0060048)2.49052804
133substantia nigra development (GO:0021762)2.48688695
134cytochrome complex assembly (GO:0017004)2.48252633
135regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.47786866
136auditory behavior (GO:0031223)2.47420109
137synaptic vesicle exocytosis (GO:0016079)2.47337240
138action potential (GO:0001508)2.47289416
139regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.46421892
140oxidative phosphorylation (GO:0006119)2.46264563
141membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.45207477
142behavioral response to ethanol (GO:0048149)2.45065715
143transcription from RNA polymerase I promoter (GO:0006360)2.44941188
144proline transport (GO:0015824)2.44504496
145regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.43344375
146DNA double-strand break processing (GO:0000729)2.42915654
147gamma-aminobutyric acid signaling pathway (GO:0007214)2.41294816
148centriole assembly (GO:0098534)2.41271413
149establishment of mitochondrion localization (GO:0051654)2.40677208
150DNA strand elongation (GO:0022616)2.39851263
151regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253)2.39838722
152response to inactivity (GO:0014854)2.39594883
153cullin deneddylation (GO:0010388)2.39286636
154establishment of protein localization to Golgi (GO:0072600)2.38472585
155ionotropic glutamate receptor signaling pathway (GO:0035235)2.38232887
156GPI anchor biosynthetic process (GO:0006506)2.37742275
157positive regulation of meiosis (GO:0045836)2.37414503
158transmission of nerve impulse (GO:0019226)2.36676402
159establishment of protein localization to mitochondrial membrane (GO:0090151)2.36566083
160transcription-coupled nucleotide-excision repair (GO:0006283)2.36215407
161regulation of cilium movement (GO:0003352)2.35811487
162skeletal muscle contraction (GO:0003009)2.35688841
163microtubule polymerization or depolymerization (GO:0031109)2.35680721
164C4-dicarboxylate transport (GO:0015740)2.35629589
165telomere maintenance via telomere lengthening (GO:0010833)2.35552823
166synaptic transmission, glutamatergic (GO:0035249)2.35368521
167transcription elongation from RNA polymerase I promoter (GO:0006362)2.34962137
168mitotic recombination (GO:0006312)2.34714960
169regulation of collateral sprouting (GO:0048670)2.34657615
170DNA synthesis involved in DNA repair (GO:0000731)2.34169610
171hydrogen ion transmembrane transport (GO:1902600)2.33999971
172nucleus localization (GO:0051647)2.33980108
173negative regulation of neurotransmitter secretion (GO:0046929)2.32988245
174parental behavior (GO:0060746)2.32825728
175mitotic metaphase plate congression (GO:0007080)2.32427272
176preassembly of GPI anchor in ER membrane (GO:0016254)2.32161121
177kinetochore assembly (GO:0051382)2.32000240
178histone H2B ubiquitination (GO:0033523)2.31984284
179protein targeting to mitochondrion (GO:0006626)2.31707870
180pyrimidine ribonucleoside catabolic process (GO:0046133)2.30467720
181relaxation of muscle (GO:0090075)2.28350737
182water-soluble vitamin biosynthetic process (GO:0042364)2.28063103
183regulation of female receptivity (GO:0045924)2.27746428

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.10157625
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.06002212
3E2F7_22180533_ChIP-Seq_HELA_Human3.52976093
4EZH2_22144423_ChIP-Seq_EOC_Human3.34847430
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.13292016
6GABP_17652178_ChIP-ChIP_JURKAT_Human2.94943664
7GBX2_23144817_ChIP-Seq_PC3_Human2.92874693
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.66752803
9ZNF274_21170338_ChIP-Seq_K562_Hela2.65817716
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.59770928
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.53246592
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.42189816
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.36516333
14HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.30974868
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.28076814
16E2F4_17652178_ChIP-ChIP_JURKAT_Human2.15011356
17NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.13838786
18FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.07907278
19TAF15_26573619_Chip-Seq_HEK293_Human1.95009617
20CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.91492830
21THAP11_20581084_ChIP-Seq_MESCs_Mouse1.91061769
22HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.90905765
23HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.77909248
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.77555310
25FLI1_27457419_Chip-Seq_LIVER_Mouse1.75004043
26PCGF2_27294783_Chip-Seq_ESCs_Mouse1.74876175
27CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.74140021
28RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.73068740
29SMAD4_21799915_ChIP-Seq_A2780_Human1.72694635
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.71025429
31FUS_26573619_Chip-Seq_HEK293_Human1.66464473
32MYC_18555785_ChIP-Seq_MESCs_Mouse1.63161957
33POU3F2_20337985_ChIP-ChIP_501MEL_Human1.60251011
34SALL1_21062744_ChIP-ChIP_HESCs_Human1.59618485
35SRF_21415370_ChIP-Seq_HL-1_Mouse1.57667872
36VDR_23849224_ChIP-Seq_CD4+_Human1.57472517
37YY1_21170310_ChIP-Seq_MESCs_Mouse1.57153554
38AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.56380466
39PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.56207785
40PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.55461529
41CBP_20019798_ChIP-Seq_JUKART_Human1.55389654
42IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.55389654
43YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.53281076
44CTBP1_25329375_ChIP-Seq_LNCAP_Human1.51258098
45STAT3_23295773_ChIP-Seq_U87_Human1.50892636
46* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.50414114
47PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.49524451
48SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.49445913
49CBX2_27304074_Chip-Seq_ESCs_Mouse1.49119497
50MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.48925507
51ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.47093076
52PIAS1_25552417_ChIP-Seq_VCAP_Human1.46856826
53TCF4_23295773_ChIP-Seq_U87_Human1.44335100
54NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.43788289
55ELF1_17652178_ChIP-ChIP_JURKAT_Human1.43344580
56EZH2_27304074_Chip-Seq_ESCs_Mouse1.40851753
57TOP2B_26459242_ChIP-Seq_MCF-7_Human1.40829546
58OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40745444
59SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40565728
60ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.38691487
61TP53_22573176_ChIP-Seq_HFKS_Human1.38537867
62* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.38100601
63SUZ12_27294783_Chip-Seq_NPCs_Mouse1.37691134
64MYC_19030024_ChIP-ChIP_MESCs_Mouse1.35725787
65AR_25329375_ChIP-Seq_VCAP_Human1.34946847
66AR_21572438_ChIP-Seq_LNCaP_Human1.34933714
67FLI1_21867929_ChIP-Seq_TH2_Mouse1.33567251
68MYC_18358816_ChIP-ChIP_MESCs_Mouse1.33111453
69REST_21632747_ChIP-Seq_MESCs_Mouse1.33095031
70RNF2_27304074_Chip-Seq_NSC_Mouse1.32549694
71ER_23166858_ChIP-Seq_MCF-7_Human1.32325932
72PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.30202854
73PADI4_21655091_ChIP-ChIP_MCF-7_Human1.28224491
74CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.27658193
75CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.27504027
76SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.26749395
77NFE2_27457419_Chip-Seq_LIVER_Mouse1.26684216
78GATA1_26923725_Chip-Seq_HPCs_Mouse1.25314361
79CRX_20693478_ChIP-Seq_RETINA_Mouse1.25096025
80ELK1_19687146_ChIP-ChIP_HELA_Human1.24305549
81NANOG_19829295_ChIP-Seq_ESCs_Human1.23223330
82SOX2_19829295_ChIP-Seq_ESCs_Human1.23223330
83REST_18959480_ChIP-ChIP_MESCs_Mouse1.23155908
84TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.22689062
85POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.22229911
86TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22229911
87FOXP3_21729870_ChIP-Seq_TREG_Human1.22154770
88OCT4_21477851_ChIP-Seq_ESCs_Mouse1.22102732
89FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.19528769
90* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.18318692
91DROSHA_22980978_ChIP-Seq_HELA_Human1.18062368
92EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.17679042
93EZH2_27294783_Chip-Seq_ESCs_Mouse1.17177204
94SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.15426937
95TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.15261004
96PRDM14_20953172_ChIP-Seq_ESCs_Human1.15210309
97SUZ12_18555785_Chip-Seq_ESCs_Mouse1.14295757
98PCGF2_27294783_Chip-Seq_NPCs_Mouse1.14252027
99BCAT_22108803_ChIP-Seq_LS180_Human1.14008627
100KLF5_20875108_ChIP-Seq_MESCs_Mouse1.13938519
101ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.13780107
102P300_18555785_Chip-Seq_ESCs_Mouse1.13457664
103JARID2_20075857_ChIP-Seq_MESCs_Mouse1.13324138
104NR3C1_21868756_ChIP-Seq_MCF10A_Human1.12765860
105EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.12684228
106SMAD4_21741376_ChIP-Seq_EPCs_Human1.12436113
107SOX2_21211035_ChIP-Seq_LN229_Gbm1.12268774
108RUNX1_27457419_Chip-Seq_LIVER_Mouse1.12031483
109TP53_16413492_ChIP-PET_HCT116_Human1.11815272
110FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.11723644
111TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.11369509
112BMI1_23680149_ChIP-Seq_NPCS_Mouse1.11111723
113CDX2_19796622_ChIP-Seq_MESCs_Mouse1.10638197
114TAL1_26923725_Chip-Seq_HPCs_Mouse1.10635882
115SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.09878932
116E2F1_18555785_Chip-Seq_ESCs_Mouse1.09762885
117RUNX2_22187159_ChIP-Seq_PCA_Human1.09123584
118SOX2_18555785_Chip-Seq_ESCs_Mouse1.08967889
119MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.08175482
120EED_16625203_ChIP-ChIP_MESCs_Mouse1.07164532
121FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.07051796
122STAT3_18555785_Chip-Seq_ESCs_Mouse1.06301862
123DCP1A_22483619_ChIP-Seq_HELA_Human1.06224461
124MTF2_20144788_ChIP-Seq_MESCs_Mouse1.04909132
125P53_22387025_ChIP-Seq_ESCs_Mouse1.04366358
126MYCN_18555785_ChIP-Seq_MESCs_Mouse1.03834401
127* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.03331374
128GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.03142824
129VDR_22108803_ChIP-Seq_LS180_Human1.02881608
130CTBP2_25329375_ChIP-Seq_LNCAP_Human1.02726331
131TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02178543
132EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.02059163
133SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.01495173
134LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01390129
135IRF1_19129219_ChIP-ChIP_H3396_Human1.01285822
136HTT_18923047_ChIP-ChIP_STHdh_Human1.01236109
137SMAD1_18555785_Chip-Seq_ESCs_Mouse1.01174607
138NANOG_18555785_Chip-Seq_ESCs_Mouse1.00996946
139* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.00829656
140NMYC_18555785_Chip-Seq_ESCs_Mouse1.00666715
141ZFX_18555785_Chip-Seq_ESCs_Mouse0.98509497
142JARID2_20064375_ChIP-Seq_MESCs_Mouse0.98030188
143* E2F1_18555785_ChIP-Seq_MESCs_Mouse0.97942064
144KLF4_18555785_Chip-Seq_ESCs_Mouse0.97887433
145MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.97755521
146CMYC_18555785_Chip-Seq_ESCs_Mouse0.96884907
147CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.94604589
148EZH2_27294783_Chip-Seq_NPCs_Mouse0.94511530
149RARB_27405468_Chip-Seq_BRAIN_Mouse0.93920521
150TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.93660535
151EWS_26573619_Chip-Seq_HEK293_Human0.92814363
152MYC_19079543_ChIP-ChIP_MESCs_Mouse0.92764417
153OCT4_18555785_Chip-Seq_ESCs_Mouse0.92241945
154IGF1R_20145208_ChIP-Seq_DFB_Human0.92118507
155SOX9_26525672_Chip-Seq_HEART_Mouse0.90474193
156SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.87946634
157NELFA_20434984_ChIP-Seq_ESCs_Mouse0.87274642
158GABP_19822575_ChIP-Seq_HepG2_Human0.86397161
159CTCF_18555785_Chip-Seq_ESCs_Mouse0.85625131
160P300_19829295_ChIP-Seq_ESCs_Human0.84997053
161GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.84324571
162SMAD3_21741376_ChIP-Seq_EPCs_Human0.83697672

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.45619161
2MP0004859_abnormal_synaptic_plasticity2.89674337
3MP0004145_abnormal_muscle_electrophysio2.73052273
4MP0004270_analgesia2.69310245
5MP0008877_abnormal_DNA_methylation2.55677816
6MP0001188_hyperpigmentation2.51028756
7MP0001984_abnormal_olfaction2.37156311
8MP0004142_abnormal_muscle_tone2.35599826
9MP0003635_abnormal_synaptic_transmissio2.24644447
10MP0003646_muscle_fatigue2.23533952
11MP0001486_abnormal_startle_reflex2.17382615
12MP0002272_abnormal_nervous_system2.12695608
13MP0006292_abnormal_olfactory_placode2.10342161
14MP0009745_abnormal_behavioral_response2.04743470
15MP0000749_muscle_degeneration1.99756173
16MP0009046_muscle_twitch1.99082204
17MP0004130_abnormal_muscle_cell1.96521879
18MP0002837_dystrophic_cardiac_calcinosis1.93490072
19MP0002734_abnormal_mechanical_nocicepti1.85172124
20MP0000566_synostosis1.85051370
21MP0004215_abnormal_myocardial_fiber1.84410592
22MP0001529_abnormal_vocalization1.84227817
23MP0006036_abnormal_mitochondrial_physio1.82126267
24MP0002064_seizures1.80358003
25MP0008057_abnormal_DNA_replication1.78056266
26MP0001485_abnormal_pinna_reflex1.77517374
27MP0002638_abnormal_pupillary_reflex1.73196658
28MP0003806_abnormal_nucleotide_metabolis1.72082033
29MP0008058_abnormal_DNA_repair1.70675754
30MP0002063_abnormal_learning/memory/cond1.70050871
31MP0000751_myopathy1.69720545
32MP0001905_abnormal_dopamine_level1.66099644
33MP0002102_abnormal_ear_morphology1.65406185
34MP0000920_abnormal_myelination1.64027535
35MP0004147_increased_porphyrin_level1.63459729
36MP0005423_abnormal_somatic_nervous1.63218043
37MP0003011_delayed_dark_adaptation1.57544572
38MP0005645_abnormal_hypothalamus_physiol1.56354448
39MP0002572_abnormal_emotion/affect_behav1.54194179
40MP0003111_abnormal_nucleus_morphology1.52813511
41MP0006035_abnormal_mitochondrial_morpho1.52789299
42MP0002163_abnormal_gland_morphology1.52479733
43MP0001501_abnormal_sleep_pattern1.51182691
44MP0002876_abnormal_thyroid_physiology1.50602236
45MP0003718_maternal_effect1.50311651
46MP0010094_abnormal_chromosome_stability1.49328497
47MP0002269_muscular_atrophy1.48468650
48MP0000569_abnormal_digit_pigmentation1.48362120
49MP0004036_abnormal_muscle_relaxation1.45386215
50MP0000747_muscle_weakness1.40095495
51MP0006072_abnormal_retinal_apoptosis1.39432951
52MP0003787_abnormal_imprinting1.37312170
53MP0003136_yellow_coat_color1.36201242
54MP0002822_catalepsy1.34285768
55MP0002067_abnormal_sensory_capabilities1.33332153
56MP0005330_cardiomyopathy1.33024122
57MP0003221_abnormal_cardiomyocyte_apopto1.32940200
58MP0003137_abnormal_impulse_conducting1.31967904
59MP0004043_abnormal_pH_regulation1.30466451
60MP0004924_abnormal_behavior1.30211409
61MP0005386_behavior/neurological_phenoty1.30211409
62MP0002229_neurodegeneration1.30198527
63MP0005171_absent_coat_pigmentation1.28565189
64MP0005253_abnormal_eye_physiology1.27528950
65MP0002928_abnormal_bile_duct1.26123855
66MP0008872_abnormal_physiological_respon1.24973224
67MP0002184_abnormal_innervation1.24620963
68MP0005084_abnormal_gallbladder_morpholo1.22030804
69MP0003693_abnormal_embryo_hatching1.21830107
70MP0001440_abnormal_grooming_behavior1.20867963
71MP0002106_abnormal_muscle_physiology1.20375640
72MP0002160_abnormal_reproductive_system1.20308010
73MP0001968_abnormal_touch/_nociception1.20203437
74MP0002733_abnormal_thermal_nociception1.19099739
75MP0004742_abnormal_vestibular_system1.18509098
76MP0000778_abnormal_nervous_system1.18399976
77MP0005499_abnormal_olfactory_system1.18320929
78MP0005394_taste/olfaction_phenotype1.18320929
79MP0002735_abnormal_chemical_nociception1.17609216
80MP0005620_abnormal_muscle_contractility1.15635667
81MP0005451_abnormal_body_composition1.13865721
82MP0008775_abnormal_heart_ventricle1.13262928
83MP0000955_abnormal_spinal_cord1.13154670
84MP0002882_abnormal_neuron_morphology1.12641987
85MP0004885_abnormal_endolymph1.10367213
86MP0002752_abnormal_somatic_nervous1.08826792
87MP0002066_abnormal_motor_capabilities/c1.08164569
88MP0005646_abnormal_pituitary_gland1.07990862
89MP0010386_abnormal_urinary_bladder1.07768274
90MP0000631_abnormal_neuroendocrine_gland1.05976191
91MP0005369_muscle_phenotype1.05622026
92MP0005551_abnormal_eye_electrophysiolog1.04774073
93MP0002972_abnormal_cardiac_muscle1.04231987
94MP0008789_abnormal_olfactory_epithelium1.03892980
95MP0006276_abnormal_autonomic_nervous1.03426044
96MP0004484_altered_response_of1.02349059
97MP0003656_abnormal_erythrocyte_physiolo1.01627144
98MP0001970_abnormal_pain_threshold1.00981194
99MP0002557_abnormal_social/conspecific_i1.00594941
100MP0000759_abnormal_skeletal_muscle1.00326101
101MP0003329_amyloid_beta_deposits1.00173339
102MP0001986_abnormal_taste_sensitivity0.99671504
103MP0000372_irregular_coat_pigmentation0.97765804
104MP0004087_abnormal_muscle_fiber0.97410141
105MP0000013_abnormal_adipose_tissue0.96156242
106MP0001502_abnormal_circadian_rhythm0.95635049
107MP0003195_calcinosis0.95498560
108MP0008995_early_reproductive_senescence0.95494315
109MP0005409_darkened_coat_color0.94712261
110MP0001963_abnormal_hearing_physiology0.94224801
111MP0003879_abnormal_hair_cell0.93223654
112MP0009379_abnormal_foot_pigmentation0.92497590
113MP0003698_abnormal_male_reproductive0.91981779
114MP0003077_abnormal_cell_cycle0.89680209
115MP0002332_abnormal_exercise_endurance0.89620673
116MP0008932_abnormal_embryonic_tissue0.88839816
117MP0003786_premature_aging0.88539295
118MP0002210_abnormal_sex_determination0.88440480
119MP0008569_lethality_at_weaning0.88151007
120MP0004811_abnormal_neuron_physiology0.86803543
121MP0004085_abnormal_heartbeat0.85986706
122MP0001544_abnormal_cardiovascular_syste0.84492708
123MP0005385_cardiovascular_system_phenoty0.84492708
124MP0002127_abnormal_cardiovascular_syste0.84374523
125MP0002938_white_spotting0.83378515
126MP0002736_abnormal_nociception_after0.82740176
127MP0005174_abnormal_tail_pigmentation0.82510657
128MP0004084_abnormal_cardiac_muscle0.81069076
129MP0000230_abnormal_systemic_arterial0.80414002
130MP0005266_abnormal_metabolism0.80143406
131MP0001929_abnormal_gametogenesis0.79726684
132MP0008260_abnormal_autophagy0.79056653
133MP0002234_abnormal_pharynx_morphology0.76699916

Predicted human phenotypes

RankGene SetZ-score
1Progressive external ophthalmoplegia (HP:0000590)4.44680553
2Acute necrotizing encephalopathy (HP:0006965)4.06365484
3Type II lissencephaly (HP:0007260)3.76337866
4Abnormal mitochondria in muscle tissue (HP:0008316)3.70704335
5Focal motor seizures (HP:0011153)3.68933981
6Cerebral hypomyelination (HP:0006808)3.67672594
7Hepatocellular necrosis (HP:0001404)3.39954498
8Progressive macrocephaly (HP:0004481)3.38480830
9Mitochondrial inheritance (HP:0001427)3.35942359
10Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.32754489
11Acute encephalopathy (HP:0006846)3.29026461
12Bundle branch block (HP:0011710)3.23174067
13Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.20727162
14Abnormality of alanine metabolism (HP:0010916)3.20727162
15Hyperalaninemia (HP:0003348)3.20727162
16Increased CSF lactate (HP:0002490)3.18009924
17Muscle fiber inclusion bodies (HP:0100299)3.14889884
18Nemaline bodies (HP:0003798)3.12243329
19Chromosomal breakage induced by crosslinking agents (HP:0003221)3.10767051
20Exercise-induced myalgia (HP:0003738)3.10673325
21Muscle hypertrophy of the lower extremities (HP:0008968)3.09234094
22Pancreatic cysts (HP:0001737)3.09002441
23Hepatic necrosis (HP:0002605)3.03618811
24Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)3.03185067
25Type 1 muscle fiber predominance (HP:0003803)2.95725208
26Molar tooth sign on MRI (HP:0002419)2.88070192
27Abnormality of midbrain morphology (HP:0002418)2.88070192
28Exercise intolerance (HP:0003546)2.87513121
29Fetal akinesia sequence (HP:0001989)2.84437845
30Abnormality of the renal cortex (HP:0011035)2.82427499
31Increased serum lactate (HP:0002151)2.79926592
32Duplicated collecting system (HP:0000081)2.78508541
33External ophthalmoplegia (HP:0000544)2.76399169
34Chromsome breakage (HP:0040012)2.76189939
35Calf muscle hypertrophy (HP:0008981)2.74807814
36Pancreatic fibrosis (HP:0100732)2.73480506
37Epileptic encephalopathy (HP:0200134)2.67546414
38Renal cortical cysts (HP:0000803)2.64965050
393-Methylglutaconic aciduria (HP:0003535)2.64367489
40Increased serum pyruvate (HP:0003542)2.61909936
41Abnormality of glycolysis (HP:0004366)2.61909936
42Atonic seizures (HP:0010819)2.57602274
43Febrile seizures (HP:0002373)2.56034229
44Absent phalangeal crease (HP:0006109)2.55937366
45Lactic acidosis (HP:0003128)2.55041358
46Nephronophthisis (HP:0000090)2.54455234
47Broad-based gait (HP:0002136)2.54303245
48Hyporeflexia of lower limbs (HP:0002600)2.52738691
49Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.48900108
50Degeneration of the lateral corticospinal tracts (HP:0002314)2.48900108
51Abnormality of the renal collecting system (HP:0004742)2.47788405
52Cerebellar dysplasia (HP:0007033)2.47637991
53Left ventricular hypertrophy (HP:0001712)2.47092542
54Optic disc pallor (HP:0000543)2.43106832
55Birth length less than 3rd percentile (HP:0003561)2.42159994
56Congenital primary aphakia (HP:0007707)2.41033046
57Aplasia/Hypoplasia of the tibia (HP:0005772)2.39179185
58Myotonia (HP:0002486)2.37927795
59Unsteady gait (HP:0002317)2.36253186
60Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.35493650
61Myokymia (HP:0002411)2.34981680
62Distal arthrogryposis (HP:0005684)2.32868487
63Abnormal drinking behavior (HP:0030082)2.32615024
64Polydipsia (HP:0001959)2.32615024
65Leukodystrophy (HP:0002415)2.30964130
66Cerebral edema (HP:0002181)2.28729780
67True hermaphroditism (HP:0010459)2.26357993
68Nephrogenic diabetes insipidus (HP:0009806)2.26247689
69Progressive muscle weakness (HP:0003323)2.24384419
70Short tibia (HP:0005736)2.23950363
71Exercise-induced muscle cramps (HP:0003710)2.23321473
72Pachygyria (HP:0001302)2.20222808
73Absence seizures (HP:0002121)2.20133424
74Congenital stationary night blindness (HP:0007642)2.16386111
75Respiratory failure (HP:0002878)2.13703408
76Ketoacidosis (HP:0001993)2.13324722
77Abnormal finger flexion creases (HP:0006143)2.11104507
78Abnormality of the renal medulla (HP:0100957)2.11067197
79Breast hypoplasia (HP:0003187)2.09943922
80Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.09098554
81Decreased activity of mitochondrial respiratory chain (HP:0008972)2.09098554
82Syncope (HP:0001279)2.08979547
83Type 2 muscle fiber atrophy (HP:0003554)2.07255742
84Ketosis (HP:0001946)2.06837858
85Abnormality of the heme biosynthetic pathway (HP:0010472)2.05798314
86Muscle fiber splitting (HP:0003555)2.05415168
87Genital tract atresia (HP:0001827)2.05140459
88Abnormality of the corticospinal tract (HP:0002492)2.04518851
89Heart block (HP:0012722)2.02984347
90Dialeptic seizures (HP:0011146)2.02935154
91Frequent falls (HP:0002359)2.02306495
92Lissencephaly (HP:0001339)2.01990481
93Prolonged QT interval (HP:0001657)2.01118823
94Delusions (HP:0000746)1.98336930
95Vaginal atresia (HP:0000148)1.97267932
96Gaze-evoked nystagmus (HP:0000640)1.97062173
97Generalized tonic-clonic seizures (HP:0002069)1.96225988
98Chronic hepatic failure (HP:0100626)1.95218599
99Progressive cerebellar ataxia (HP:0002073)1.93944313
100Poor coordination (HP:0002370)1.92416536
101Increased hepatocellular lipid droplets (HP:0006565)1.91461200
102Rimmed vacuoles (HP:0003805)1.91249089
103Sudden death (HP:0001699)1.89506545
104Abnormality of the calf musculature (HP:0001430)1.89026021
105Microvesicular hepatic steatosis (HP:0001414)1.89014268
106Drooling (HP:0002307)1.87246492
107Anterior segment dysgenesis (HP:0007700)1.86647174
108CNS hypomyelination (HP:0003429)1.86190937
109Methylmalonic acidemia (HP:0002912)1.83469960
110Inability to walk (HP:0002540)1.83381424
111Focal seizures (HP:0007359)1.83210874
112Retinal dysplasia (HP:0007973)1.83031557
113Hemiparesis (HP:0001269)1.82639232
114Atrial fibrillation (HP:0005110)1.81975808
115Spastic gait (HP:0002064)1.81301015
116Poor eye contact (HP:0000817)1.81223717
117CNS demyelination (HP:0007305)1.81186965
118Abnormality of chromosome stability (HP:0003220)1.80454200
119Proximal tubulopathy (HP:0000114)1.80140742
120Increased intramyocellular lipid droplets (HP:0012240)1.79940165
121Aplasia/Hypoplasia of the earlobes (HP:0009906)1.79118772
122Absent speech (HP:0001344)1.78281376
123Hyperglycinemia (HP:0002154)1.77876951
124Athetosis (HP:0002305)1.77185888
125Optic nerve hypoplasia (HP:0000609)1.75968279
126Stomach cancer (HP:0012126)1.75507121
127Muscle stiffness (HP:0003552)1.75248913
128Cortical visual impairment (HP:0100704)1.74364284
129Hyperventilation (HP:0002883)1.73995435
130Absent/shortened dynein arms (HP:0200106)1.73682716
131Dynein arm defect of respiratory motile cilia (HP:0012255)1.73682716
132Primary atrial arrhythmia (HP:0001692)1.73594204
133Gait imbalance (HP:0002141)1.72991217
134Abnormality of the preputium (HP:0100587)1.72980505
135Visual hallucinations (HP:0002367)1.71772215
136Myopathic facies (HP:0002058)1.71597020
137Lipid accumulation in hepatocytes (HP:0006561)1.70283975
138Anxiety (HP:0000739)1.70202110
139Hyperkalemia (HP:0002153)1.70037256
140Abnormality of the septum pellucidum (HP:0007375)1.69850522
141Status epilepticus (HP:0002133)1.69845288
142Increased muscle lipid content (HP:0009058)1.69747126
143Central scotoma (HP:0000603)1.68678446
144Palpitations (HP:0001962)1.68153754
145Abnormal EKG (HP:0003115)1.67590417
146Meckel diverticulum (HP:0002245)1.67540673
147Myoglobinuria (HP:0002913)1.67119359
148Protruding tongue (HP:0010808)1.66769899
149Dysmetria (HP:0001310)1.66611893
150Abnormality of the left ventricular outflow tract (HP:0011103)1.66570896
151Subaortic stenosis (HP:0001682)1.66570896
152Polyuria (HP:0000103)1.66358088
153Aplasia/Hypoplasia involving the musculature (HP:0001460)1.66306402
154EMG: myopathic abnormalities (HP:0003458)1.65817106
155Parakeratosis (HP:0001036)1.65536627
156Medial flaring of the eyebrow (HP:0010747)1.65143920
157Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.64686715

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK13.81063978
2STK163.79904795
3IRAK33.67202007
4FRK2.90606291
5PLK42.85232707
6ZAK2.78801726
7TAOK32.73916533
8TIE12.70461005
9CDK192.64516524
10MAP2K72.61806516
11TXK2.47428277
12EIF2AK12.38942579
13PRPF4B2.20010458
14PNCK2.19619684
15MAP3K42.17292759
16ADRBK22.01419981
17PHKG21.99277539
18PHKG11.99277539
19EPHA41.89353029
20PINK11.87680016
21STK391.83837830
22OBSCN1.83396781
23NME11.78133105
24BUB11.74518328
25OXSR11.73908620
26IRAK21.72220906
27BMPR1B1.70950334
28TNIK1.68630300
29NEK61.64713884
30IRAK11.63887702
31NTRK21.62087410
32PAK31.60987635
33MAP3K61.60777912
34BCKDK1.60082533
35MAP4K21.59495958
36MAP3K131.58734588
37IRAK41.58187782
38CASK1.41933964
39SRPK11.38197538
40WEE11.37508261
41TTK1.36913087
42WNK31.30123183
43MAP2K41.29586845
44PIK3CA1.28538075
45NEK11.25797323
46CDC71.25786916
47PLK21.22506311
48TEC1.21034492
49EIF2AK31.16919290
50GRK11.14401890
51CAMK2B1.12098300
52CAMK2D1.09695704
53MINK11.03165172
54NTRK31.02857901
55AKT31.01526031
56CAMK2G0.99367668
57WNK40.98690107
58NUAK10.93676452
59PBK0.92695326
60BCR0.91661267
61PLK30.91295047
62FGFR20.88634342
63BRSK20.87409522
64PKN10.87102315
65CHEK20.85155330
66TRIM280.80730438
67PLK10.80454749
68PRKCG0.77485331
69CSNK1A1L0.75358965
70TSSK60.74550068
71DMPK0.74426871
72BRAF0.72047021
73DYRK20.71767845
74BRSK10.71265628
75CCNB10.70827303
76CSNK1G30.70718900
77SGK20.69763781
78CAMK10.69082449
79PIK3CG0.68812545
80PRKCQ0.67602057
81MKNK20.67408916
82PDK40.66877658
83PDK30.66877658
84ARAF0.66329081
85CAMK2A0.65703529
86BMPR20.64982989
87PRKAA10.64534147
88CLK10.63877747
89PRKCI0.63835839
90EPHA30.62548632
91STK240.62374594
92CDK30.61594416
93AURKA0.57918841
94MAPKAPK30.57803320
95PRKACA0.57754308
96ADRBK10.57400932
97ERBB30.57217908
98TTN0.57111783
99EIF2AK20.57028674
100MAP3K90.57012297
101PRKG10.56958012
102CDK11A0.56795976
103SGK10.56542503
104MAPK120.55086504
105CDK150.54550948
106CAMKK20.54244456
107CDK180.54004049
108MUSK0.53484428
109CSNK1G20.52922982
110DYRK1A0.52343658
111CDK140.52076334
112CDK50.51447269
113STK38L0.51059876
114STK110.51014765
115LIMK10.50766184
116MAPK130.50380227
117GRK50.48931686
118VRK10.47673943
119SIK20.47454612
120ATR0.46608498
121ROCK20.46531759
122MAP3K70.46083405
123BRD40.43894613
124UHMK10.43675075
125CDC42BPA0.42687407
126DYRK30.42125469
127ABL20.42103287
128MKNK10.41850637
129DAPK20.41128803
130MAP3K120.40876240
131GRK70.40268938
132PRKAA20.40007886
133PRKCE0.39706020
134RPS6KA30.39027807
135RAF10.38816487
136DAPK10.37268550
137MAPK150.37096542
138CSNK1G10.36200785
139CAMK40.36158694
140MAP2K10.35820008
141INSRR0.33594048
142CAMKK10.33288609
143CHEK10.33086548
144TLK10.32063846
145CSNK1D0.31977324
146PRKACB0.31543945
147PRKACG0.31325689
148MAP2K20.30593451
149ATM0.30454820
150ITK0.30244556
151PDK20.30074884
152PRKCA0.30022666
153SGK30.29986251
154SGK4940.29786848
155SGK2230.29786848
156PAK60.29460370

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001903.85975620
2Parkinsons disease_Homo sapiens_hsa050123.46344810
3DNA replication_Homo sapiens_hsa030302.95993980
4RNA polymerase_Homo sapiens_hsa030202.93277403
5Alzheimers disease_Homo sapiens_hsa050102.66403657
6Proteasome_Homo sapiens_hsa030502.65981260
7Huntingtons disease_Homo sapiens_hsa050162.61416439
8Olfactory transduction_Homo sapiens_hsa047402.57827184
9Cardiac muscle contraction_Homo sapiens_hsa042602.34908434
10Mismatch repair_Homo sapiens_hsa034302.30758933
11Fanconi anemia pathway_Homo sapiens_hsa034602.23720665
12Nitrogen metabolism_Homo sapiens_hsa009102.18447303
13Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.17298925
14Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.13038613
15Homologous recombination_Homo sapiens_hsa034402.08816484
16Nicotine addiction_Homo sapiens_hsa050332.05284329
17Pyrimidine metabolism_Homo sapiens_hsa002401.81362883
18Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.77801568
19Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.75295941
20Purine metabolism_Homo sapiens_hsa002301.67933717
21Vitamin B6 metabolism_Homo sapiens_hsa007501.64303113
22Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.64201094
23Synaptic vesicle cycle_Homo sapiens_hsa047211.63862655
24Phototransduction_Homo sapiens_hsa047441.60729344
25Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.55697196
26Fatty acid elongation_Homo sapiens_hsa000621.54653781
27Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.53522893
28Nucleotide excision repair_Homo sapiens_hsa034201.51764206
29Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.48187655
30alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.47948309
31Basal transcription factors_Homo sapiens_hsa030221.47884969
32Morphine addiction_Homo sapiens_hsa050321.38246149
33GABAergic synapse_Homo sapiens_hsa047271.33033790
34Collecting duct acid secretion_Homo sapiens_hsa049661.21565333
35Tryptophan metabolism_Homo sapiens_hsa003801.20435560
36Circadian entrainment_Homo sapiens_hsa047131.17335690
37Glutamatergic synapse_Homo sapiens_hsa047241.15458280
38Cocaine addiction_Homo sapiens_hsa050301.13829746
39Oocyte meiosis_Homo sapiens_hsa041141.12200967
40Maturity onset diabetes of the young_Homo sapiens_hsa049501.11211088
41Spliceosome_Homo sapiens_hsa030401.10045773
42Selenocompound metabolism_Homo sapiens_hsa004501.02975864
43Taste transduction_Homo sapiens_hsa047421.00566477
44Peroxisome_Homo sapiens_hsa041460.99490198
45Amphetamine addiction_Homo sapiens_hsa050310.99428722
46Calcium signaling pathway_Homo sapiens_hsa040200.98234851
47Butanoate metabolism_Homo sapiens_hsa006500.98001184
48Propanoate metabolism_Homo sapiens_hsa006400.97992854
49Cell cycle_Homo sapiens_hsa041100.97893482
50Serotonergic synapse_Homo sapiens_hsa047260.96671048
51Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.96394579
52Dopaminergic synapse_Homo sapiens_hsa047280.94238646
53RNA transport_Homo sapiens_hsa030130.92869205
54Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.90803265
55Long-term potentiation_Homo sapiens_hsa047200.90297727
56Cysteine and methionine metabolism_Homo sapiens_hsa002700.89946200
57RNA degradation_Homo sapiens_hsa030180.89075737
58Non-homologous end-joining_Homo sapiens_hsa034500.88887328
59Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.88014503
60Ether lipid metabolism_Homo sapiens_hsa005650.87998110
61Ribosome_Homo sapiens_hsa030100.86746447
62cGMP-PKG signaling pathway_Homo sapiens_hsa040220.86493588
63Aldosterone synthesis and secretion_Homo sapiens_hsa049250.85902292
64Protein export_Homo sapiens_hsa030600.85589106
65SNARE interactions in vesicular transport_Homo sapiens_hsa041300.84702080
66* Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.82349620
67Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.81894163
68Arginine and proline metabolism_Homo sapiens_hsa003300.81593990
69beta-Alanine metabolism_Homo sapiens_hsa004100.79450483
70Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.77977557
712-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.77763478
72Metabolic pathways_Homo sapiens_hsa011000.77659105
73Fatty acid metabolism_Homo sapiens_hsa012120.76937142
74Glutathione metabolism_Homo sapiens_hsa004800.75415604
75ABC transporters_Homo sapiens_hsa020100.74639146
76Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.71862414
77Base excision repair_Homo sapiens_hsa034100.70610153
78Cholinergic synapse_Homo sapiens_hsa047250.70232446
79Insulin secretion_Homo sapiens_hsa049110.70010038
80Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.68054050
81Glucagon signaling pathway_Homo sapiens_hsa049220.67759727
82Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.66078484
83Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.65904282
84Ovarian steroidogenesis_Homo sapiens_hsa049130.65414497
85Oxytocin signaling pathway_Homo sapiens_hsa049210.64238403
86Regulation of autophagy_Homo sapiens_hsa041400.63399966
87Fatty acid biosynthesis_Homo sapiens_hsa000610.62847428
88Carbon metabolism_Homo sapiens_hsa012000.59747927
89Vibrio cholerae infection_Homo sapiens_hsa051100.59372085
90Dorso-ventral axis formation_Homo sapiens_hsa043200.58682710
91Arachidonic acid metabolism_Homo sapiens_hsa005900.58670170
92Pancreatic secretion_Homo sapiens_hsa049720.58463693
93Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.58413127
94Pyruvate metabolism_Homo sapiens_hsa006200.57897404
95mRNA surveillance pathway_Homo sapiens_hsa030150.57270988
96Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.56327191
97Primary bile acid biosynthesis_Homo sapiens_hsa001200.55229045
98Alcoholism_Homo sapiens_hsa050340.55118845
99Dilated cardiomyopathy_Homo sapiens_hsa054140.54915391
100Linoleic acid metabolism_Homo sapiens_hsa005910.53722963
101Salivary secretion_Homo sapiens_hsa049700.53173280
102Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52598524
103Steroid biosynthesis_Homo sapiens_hsa001000.51253529
104Sphingolipid metabolism_Homo sapiens_hsa006000.49661453
105Histidine metabolism_Homo sapiens_hsa003400.49054826
106Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.48600580
107Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.48578082
108Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.45728160
109Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.45567975
110Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.45042826
111Systemic lupus erythematosus_Homo sapiens_hsa053220.44153502
112Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.42719132
113Renin secretion_Homo sapiens_hsa049240.42563602
114Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.42431417
115Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.42287800
116Fatty acid degradation_Homo sapiens_hsa000710.41518877
117Thyroid hormone synthesis_Homo sapiens_hsa049180.41403405
118One carbon pool by folate_Homo sapiens_hsa006700.39728684
119Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.39522325
120Ras signaling pathway_Homo sapiens_hsa040140.38591285
121Cyanoamino acid metabolism_Homo sapiens_hsa004600.37471210
122Vascular smooth muscle contraction_Homo sapiens_hsa042700.37298715
123Gastric acid secretion_Homo sapiens_hsa049710.37125299
124MAPK signaling pathway_Homo sapiens_hsa040100.37115830
125Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.36570956
126Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.36493221
127Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.36071970
128Circadian rhythm_Homo sapiens_hsa047100.34931328
129Steroid hormone biosynthesis_Homo sapiens_hsa001400.34177933
130Gap junction_Homo sapiens_hsa045400.33775701
131Epstein-Barr virus infection_Homo sapiens_hsa051690.33450320
132cAMP signaling pathway_Homo sapiens_hsa040240.33415461
133Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.32327226
134Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.31946827
135Long-term depression_Homo sapiens_hsa047300.31707263

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