

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | detection of molecule of bacterial origin (GO:0032490) | 7.48241689 |
| 2 | modulation by symbiont of host immune response (GO:0052553) | 7.14431368 |
| 3 | positive regulation by symbiont of host defense response (GO:0052509) | 7.14431368 |
| 4 | modulation by symbiont of host defense response (GO:0052031) | 7.14431368 |
| 5 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 7.14431368 |
| 6 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 7.14431368 |
| 7 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 7.14431368 |
| 8 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 6.85587443 |
| 9 | regulation of interferon-beta biosynthetic process (GO:0045357) | 5.80713214 |
| 10 | macrophage activation involved in immune response (GO:0002281) | 5.68284520 |
| 11 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 5.56810241 |
| 12 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.52823829 |
| 13 | microglial cell activation (GO:0001774) | 5.52102944 |
| 14 | detection of external biotic stimulus (GO:0098581) | 5.41504682 |
| 15 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.41105476 |
| 16 | negative regulation of cell killing (GO:0031342) | 5.39565678 |
| 17 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.39565678 |
| 18 | neutrophil activation involved in immune response (GO:0002283) | 5.27689145 |
| 19 | cellular extravasation (GO:0045123) | 5.13658954 |
| 20 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 5.06245840 |
| 21 | response to host immune response (GO:0052572) | 4.92077920 |
| 22 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.92077920 |
| 23 | leukocyte migration involved in inflammatory response (GO:0002523) | 4.85761940 |
| 24 | macrophage activation (GO:0042116) | 4.83555360 |
| 25 | detection of other organism (GO:0098543) | 4.80245321 |
| 26 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.70659863 |
| 27 | detection of biotic stimulus (GO:0009595) | 4.70087549 |
| 28 | neutrophil mediated immunity (GO:0002446) | 4.64767544 |
| 29 | neutrophil activation (GO:0042119) | 4.58152503 |
| 30 | response to peptidoglycan (GO:0032494) | 4.42076831 |
| 31 | response to host (GO:0075136) | 4.39326545 |
| 32 | response to host defenses (GO:0052200) | 4.39326545 |
| 33 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 4.39326545 |
| 34 | negative regulation of interleukin-12 production (GO:0032695) | 4.12295089 |
| 35 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.08061234 |
| 36 | production of molecular mediator involved in inflammatory response (GO:0002532) | 4.04476398 |
| 37 | response to interleukin-15 (GO:0070672) | 4.01177751 |
| 38 | granulocyte activation (GO:0036230) | 4.00602975 |
| 39 | regulation of gamma-delta T cell activation (GO:0046643) | 3.96248054 |
| 40 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.94524618 |
| 41 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.91682570 |
| 42 | myeloid leukocyte mediated immunity (GO:0002444) | 3.91373963 |
| 43 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.88114760 |
| 44 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.88017845 |
| 45 | detection of bacterium (GO:0016045) | 3.86256826 |
| 46 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.85386736 |
| 47 | respiratory burst (GO:0045730) | 3.85019085 |
| 48 | myeloid cell activation involved in immune response (GO:0002275) | 3.84604484 |
| 49 | leukocyte aggregation (GO:0070486) | 3.75819516 |
| 50 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.75620484 |
| 51 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.72672913 |
| 52 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.69026006 |
| 53 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.69026006 |
| 54 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.66204543 |
| 55 | cellular response to interleukin-15 (GO:0071350) | 3.60300082 |
| 56 | negative regulation of interleukin-1 production (GO:0032692) | 3.58338248 |
| 57 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.56618345 |
| 58 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.51572562 |
| 59 | negative regulation of B cell mediated immunity (GO:0002713) | 3.51572562 |
| 60 | positive regulation of interferon-alpha production (GO:0032727) | 3.49959501 |
| 61 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.49567043 |
| 62 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.38835796 |
| 63 | negative regulation of interleukin-1 beta production (GO:0032691) | 3.38568054 |
| 64 | positive regulation of macrophage cytokine production (GO:0060907) | 3.36668649 |
| 65 | negative regulation of T cell mediated immunity (GO:0002710) | 3.34983473 |
| 66 | B cell receptor signaling pathway (GO:0050853) | 3.31082499 |
| 67 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.30753834 |
| 68 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.28519456 |
| 69 | dendritic cell migration (GO:0036336) | 3.25374867 |
| 70 | positive regulation of mast cell activation (GO:0033005) | 3.24719226 |
| 71 | I-kappaB phosphorylation (GO:0007252) | 3.21652706 |
| 72 | regulation of interferon-alpha production (GO:0032647) | 3.21236152 |
| 73 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.20910963 |
| 74 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.15993385 |
| 75 | regulation of mast cell degranulation (GO:0043304) | 3.14372401 |
| 76 | T-helper 1 type immune response (GO:0042088) | 3.13953519 |
| 77 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.13825312 |
| 78 | neutrophil chemotaxis (GO:0030593) | 3.13659346 |
| 79 | regulation of mast cell activation (GO:0033003) | 3.11649921 |
| 80 | regulation of macrophage cytokine production (GO:0010935) | 3.10467222 |
| 81 | defense response to protozoan (GO:0042832) | 3.08417242 |
| 82 | neutrophil migration (GO:1990266) | 3.05659157 |
| 83 | leukocyte degranulation (GO:0043299) | 3.01308288 |
| 84 | immunoglobulin mediated immune response (GO:0016064) | 3.00269443 |
| 85 | germinal center formation (GO:0002467) | 2.97489252 |
| 86 | myeloid leukocyte activation (GO:0002274) | 2.96175140 |
| 87 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.96043201 |
| 88 | negative regulation of interleukin-17 production (GO:0032700) | 2.94712662 |
| 89 | negative regulation of B cell proliferation (GO:0030889) | 2.93957581 |
| 90 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.92806034 |
| 91 | negative regulation of adaptive immune response (GO:0002820) | 2.92356407 |
| 92 | dendritic cell chemotaxis (GO:0002407) | 2.91211360 |
| 93 | regulation of regulatory T cell differentiation (GO:0045589) | 2.89590104 |
| 94 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.89251307 |
| 95 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.88507436 |
| 96 | activated T cell proliferation (GO:0050798) | 2.87928978 |
| 97 | pantothenate metabolic process (GO:0015939) | 2.83868993 |
| 98 | regulation of toll-like receptor signaling pathway (GO:0034121) | 2.82939947 |
| 99 | positive regulation of interferon-beta production (GO:0032728) | 2.80124582 |
| 100 | negative regulation of interleukin-6 production (GO:0032715) | 2.73508283 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.58201585 |
| 2 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.30030175 |
| 3 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.02756146 |
| 4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.84155661 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.51472798 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.46745081 |
| 7 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.15381827 |
| 8 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.98604519 |
| 9 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.73359512 |
| 10 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.67766083 |
| 11 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.62422390 |
| 12 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.51714619 |
| 13 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.48730323 |
| 14 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.43591930 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.40219286 |
| 16 | SPI1_23127762_ChIP-Seq_K562_Human | 2.39448974 |
| 17 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.38423241 |
| 18 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.29220729 |
| 19 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.23117794 |
| 20 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.13303432 |
| 21 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.12421087 |
| 22 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.99095322 |
| 23 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.93856046 |
| 24 | MYB_26560356_Chip-Seq_TH2_Human | 1.87452685 |
| 25 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.82815619 |
| 26 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.74376091 |
| 27 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.74355065 |
| 28 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.66474946 |
| 29 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.64247204 |
| 30 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.62444876 |
| 31 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.59105678 |
| 32 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.56626553 |
| 33 | MYB_26560356_Chip-Seq_TH1_Human | 1.56218815 |
| 34 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.55080039 |
| 35 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.48799499 |
| 36 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.48397699 |
| 37 | GATA1_22025678_ChIP-Seq_K562_Human | 1.48104926 |
| 38 | GATA3_26560356_Chip-Seq_TH2_Human | 1.47605191 |
| 39 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.44745618 |
| 40 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.44528210 |
| 41 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.40616260 |
| 42 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.36882868 |
| 43 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.34633898 |
| 44 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.34335802 |
| 45 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.32784445 |
| 46 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.32588362 |
| 47 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.31348416 |
| 48 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.30975914 |
| 49 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.30700402 |
| 50 | MAF_26560356_Chip-Seq_TH1_Human | 1.30647586 |
| 51 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.26159393 |
| 52 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.24009199 |
| 53 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.20873822 |
| 54 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20246902 |
| 55 | UTX_26944678_Chip-Seq_JUKART_Human | 1.19632808 |
| 56 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.17766413 |
| 57 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.15866357 |
| 58 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.15268293 |
| 59 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.09236529 |
| 60 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.04826567 |
| 61 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.04809558 |
| 62 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.04092336 |
| 63 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.02809397 |
| 64 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.98669373 |
| 65 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.98644059 |
| 66 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.98126238 |
| 67 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.97488614 |
| 68 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.96386594 |
| 69 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.96192296 |
| 70 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.96192296 |
| 71 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.95520395 |
| 72 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.93450943 |
| 73 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.92537364 |
| 74 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 0.91918599 |
| 75 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.89959066 |
| 76 | GATA2_19941826_ChIP-Seq_K562_Human | 0.89455445 |
| 77 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.89017593 |
| 78 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.88279988 |
| 79 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.86868116 |
| 80 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.86502690 |
| 81 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.85115115 |
| 82 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.85097044 |
| 83 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.82335016 |
| 84 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.81931944 |
| 85 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.80339185 |
| 86 | TP53_16413492_ChIP-PET_HCT116_Human | 0.80091993 |
| 87 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.79553734 |
| 88 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.79119295 |
| 89 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.78970939 |
| 90 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.77148422 |
| 91 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.76959324 |
| 92 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.76690855 |
| 93 | GATA1_19941826_ChIP-Seq_K562_Human | 0.75422534 |
| 94 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.75136019 |
| 95 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.74898957 |
| 96 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.74483472 |
| 97 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.73769686 |
| 98 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.73015523 |
| 99 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.73011227 |
| 100 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.72600635 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 6.94426317 |
| 2 | MP0003436_decreased_susceptibility_to | 3.57233480 |
| 3 | MP0000569_abnormal_digit_pigmentation | 3.44139866 |
| 4 | MP0003303_peritoneal_inflammation | 3.36926696 |
| 5 | MP0001835_abnormal_antigen_presentation | 3.26202837 |
| 6 | MP0002419_abnormal_innate_immunity | 2.89398006 |
| 7 | MP0008260_abnormal_autophagy | 2.63596319 |
| 8 | MP0001800_abnormal_humoral_immune | 2.52450956 |
| 9 | MP0000015_abnormal_ear_pigmentation | 2.51372757 |
| 10 | MP0009785_altered_susceptibility_to | 2.49341209 |
| 11 | MP0005025_abnormal_response_to | 2.46310502 |
| 12 | MP0005671_abnormal_response_to | 2.42206640 |
| 13 | MP0004381_abnormal_hair_follicle | 2.39424458 |
| 14 | MP0005000_abnormal_immune_tolerance | 2.36852152 |
| 15 | MP0000685_abnormal_immune_system | 2.28616856 |
| 16 | MP0002723_abnormal_immune_serum | 2.28576700 |
| 17 | MP0005464_abnormal_platelet_physiology | 2.26105631 |
| 18 | MP0003191_abnormal_cellular_cholesterol | 2.23446597 |
| 19 | MP0002420_abnormal_adaptive_immunity | 2.14151114 |
| 20 | MP0001819_abnormal_immune_cell | 2.11935064 |
| 21 | MP0002452_abnormal_antigen_presenting | 2.11682418 |
| 22 | MP0001790_abnormal_immune_system | 2.08297227 |
| 23 | MP0005387_immune_system_phenotype | 2.08297227 |
| 24 | MP0002132_abnormal_respiratory_system | 2.03135318 |
| 25 | MP0001533_abnormal_skeleton_physiology | 1.97421693 |
| 26 | MP0006082_CNS_inflammation | 1.89131649 |
| 27 | MP0002148_abnormal_hypersensitivity_rea | 1.89017681 |
| 28 | MP0000465_gastrointestinal_hemorrhage | 1.87970446 |
| 29 | MP0003828_pulmonary_edema | 1.86041332 |
| 30 | MP0003787_abnormal_imprinting | 1.85942443 |
| 31 | MP0009278_abnormal_bone_marrow | 1.75235783 |
| 32 | MP0009764_decreased_sensitivity_to | 1.71863106 |
| 33 | MP0002277_abnormal_respiratory_mucosa | 1.71409315 |
| 34 | MP0004883_abnormal_blood_vessel | 1.68135544 |
| 35 | MP0005174_abnormal_tail_pigmentation | 1.64962849 |
| 36 | MP0002405_respiratory_system_inflammati | 1.63965283 |
| 37 | MP0002396_abnormal_hematopoietic_system | 1.61679507 |
| 38 | MP0005075_abnormal_melanosome_morpholog | 1.60171042 |
| 39 | MP0000716_abnormal_immune_system | 1.58863811 |
| 40 | MP0005451_abnormal_body_composition | 1.57840398 |
| 41 | MP0002398_abnormal_bone_marrow | 1.56978981 |
| 42 | MP0001845_abnormal_inflammatory_respons | 1.53147119 |
| 43 | MP0003172_abnormal_lysosome_physiology | 1.49048898 |
| 44 | MP0003183_abnormal_peptide_metabolism | 1.47097626 |
| 45 | MP0003866_abnormal_defecation | 1.45612044 |
| 46 | MP0003300_gastrointestinal_ulcer | 1.45486173 |
| 47 | MP0001545_abnormal_hematopoietic_system | 1.40952952 |
| 48 | MP0005397_hematopoietic_system_phenotyp | 1.40952952 |
| 49 | MP0003763_abnormal_thymus_physiology | 1.35289951 |
| 50 | MP0003690_abnormal_glial_cell | 1.35031236 |
| 51 | MP0004130_abnormal_muscle_cell | 1.34439824 |
| 52 | MP0003075_altered_response_to | 1.31979569 |
| 53 | MP0005164_abnormal_response_to | 1.30437990 |
| 54 | MP0008877_abnormal_DNA_methylation | 1.29097308 |
| 55 | MP0002722_abnormal_immune_system | 1.28684940 |
| 56 | MP0000689_abnormal_spleen_morphology | 1.27846137 |
| 57 | MP0010155_abnormal_intestine_physiology | 1.25813614 |
| 58 | MP0004947_skin_inflammation | 1.20229759 |
| 59 | MP0002429_abnormal_blood_cell | 1.18383139 |
| 60 | MP0008469_abnormal_protein_level | 1.10486997 |
| 61 | MP0002166_altered_tumor_susceptibility | 1.07267321 |
| 62 | MP0000703_abnormal_thymus_morphology | 1.06050391 |
| 63 | MP0008004_abnormal_stomach_pH | 1.05903408 |
| 64 | MP0000858_altered_metastatic_potential | 1.03528402 |
| 65 | MP0002998_abnormal_bone_remodeling | 1.03196954 |
| 66 | MP0001851_eye_inflammation | 1.02975347 |
| 67 | MP0003045_fibrosis | 1.01226947 |
| 68 | MP0004484_altered_response_of | 1.00325545 |
| 69 | MP0005409_darkened_coat_color | 0.98250699 |
| 70 | MP0005408_hypopigmentation | 0.96003310 |
| 71 | MP0000371_diluted_coat_color | 0.95041633 |
| 72 | MP0002332_abnormal_exercise_endurance | 0.94427363 |
| 73 | MP0000372_irregular_coat_pigmentation | 0.92596369 |
| 74 | MP0005310_abnormal_salivary_gland | 0.92035592 |
| 75 | MP0003221_abnormal_cardiomyocyte_apopto | 0.87976061 |
| 76 | MP0005377_hearing/vestibular/ear_phenot | 0.86253972 |
| 77 | MP0003878_abnormal_ear_physiology | 0.86253972 |
| 78 | MP0002095_abnormal_skin_pigmentation | 0.84307757 |
| 79 | MP0005083_abnormal_biliary_tract | 0.82563795 |
| 80 | MP0003656_abnormal_erythrocyte_physiolo | 0.77506965 |
| 81 | MP0005166_decreased_susceptibility_to | 0.77236350 |
| 82 | MP0004808_abnormal_hematopoietic_stem | 0.76015709 |
| 83 | MP0000604_amyloidosis | 0.75263844 |
| 84 | MP0002928_abnormal_bile_duct | 0.74399482 |
| 85 | MP0003136_yellow_coat_color | 0.72554273 |
| 86 | MP0002006_tumorigenesis | 0.70638644 |
| 87 | MP0000920_abnormal_myelination | 0.69913039 |
| 88 | MP0008874_decreased_physiological_sensi | 0.69600712 |
| 89 | MP0003448_altered_tumor_morphology | 0.69063042 |
| 90 | MP0009763_increased_sensitivity_to | 0.68849057 |
| 91 | MP0004510_myositis | 0.67765951 |
| 92 | MP0001663_abnormal_digestive_system | 0.67694877 |
| 93 | MP0002102_abnormal_ear_morphology | 0.66390852 |
| 94 | MP0003252_abnormal_bile_duct | 0.65476069 |
| 95 | MP0000343_altered_response_to | 0.64963447 |
| 96 | MP0008057_abnormal_DNA_replication | 0.64762378 |
| 97 | MP0009333_abnormal_splenocyte_physiolog | 0.64600672 |
| 98 | MP0001324_abnormal_eye_pigmentation | 0.63911714 |
| 99 | MP0005248_abnormal_Harderian_gland | 0.63282724 |
| 100 | MP0005390_skeleton_phenotype | 0.60933640 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Orchitis (HP:0100796) | 6.30174593 |
| 2 | Optic neuritis (HP:0100653) | 6.24775747 |
| 3 | Retrobulbar optic neuritis (HP:0100654) | 6.24775747 |
| 4 | Eczematoid dermatitis (HP:0000976) | 6.09045997 |
| 5 | Recurrent bacterial skin infections (HP:0005406) | 6.07215384 |
| 6 | Myositis (HP:0100614) | 6.05033823 |
| 7 | Recurrent abscess formation (HP:0002722) | 5.99338743 |
| 8 | Stomatitis (HP:0010280) | 5.11031792 |
| 9 | Keratoconjunctivitis sicca (HP:0001097) | 4.63471226 |
| 10 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.62161837 |
| 11 | Abnormality of macrophages (HP:0004311) | 4.54566965 |
| 12 | Gastrointestinal infarctions (HP:0005244) | 4.54266422 |
| 13 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.40915347 |
| 14 | Keratoconjunctivitis (HP:0001096) | 4.29740835 |
| 15 | Recurrent fungal infections (HP:0002841) | 4.11326160 |
| 16 | Recurrent skin infections (HP:0001581) | 3.94278756 |
| 17 | Spontaneous hematomas (HP:0007420) | 3.89986040 |
| 18 | Peritonitis (HP:0002586) | 3.89275917 |
| 19 | Gingival bleeding (HP:0000225) | 3.80250953 |
| 20 | Encephalitis (HP:0002383) | 3.80096271 |
| 21 | Gingivitis (HP:0000230) | 3.75375236 |
| 22 | Recurrent cutaneous fungal infections (HP:0011370) | 3.67992544 |
| 23 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.67992544 |
| 24 | Meningitis (HP:0001287) | 3.61898830 |
| 25 | Arterial thrombosis (HP:0004420) | 3.57805314 |
| 26 | Mediastinal lymphadenopathy (HP:0100721) | 3.55230528 |
| 27 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.54456304 |
| 28 | Obstructive lung disease (HP:0006536) | 3.52685451 |
| 29 | Chronic obstructive pulmonary disease (HP:0006510) | 3.52685451 |
| 30 | T lymphocytopenia (HP:0005403) | 3.41339025 |
| 31 | Abnormality of T cell number (HP:0011839) | 3.38330439 |
| 32 | Prolonged bleeding time (HP:0003010) | 3.34622453 |
| 33 | Hemoptysis (HP:0002105) | 3.25114228 |
| 34 | Episodic fever (HP:0001954) | 3.21611754 |
| 35 | Chest pain (HP:0100749) | 3.19496068 |
| 36 | Vasculitis (HP:0002633) | 3.16647035 |
| 37 | Urticaria (HP:0001025) | 3.14954587 |
| 38 | Pulmonary embolism (HP:0002204) | 3.09094764 |
| 39 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 3.08024444 |
| 40 | Epistaxis (HP:0000421) | 2.98286527 |
| 41 | Gangrene (HP:0100758) | 2.96849218 |
| 42 | Anorexia (HP:0002039) | 2.92093695 |
| 43 | Leukocytosis (HP:0001974) | 2.71419636 |
| 44 | Abnormality of the endocardium (HP:0004306) | 2.68466578 |
| 45 | Pulmonary infiltrates (HP:0002113) | 2.66617431 |
| 46 | Increased IgE level (HP:0003212) | 2.59727236 |
| 47 | Abnormality of T cells (HP:0002843) | 2.56663734 |
| 48 | Cellulitis (HP:0100658) | 2.52021398 |
| 49 | Abnormality of the peritoneum (HP:0002585) | 2.51008825 |
| 50 | Subacute progressive viral hepatitis (HP:0006572) | 2.50058440 |
| 51 | Abnormality of the pleura (HP:0002103) | 2.48207369 |
| 52 | Papilledema (HP:0001085) | 2.40588957 |
| 53 | Hypochromic microcytic anemia (HP:0004840) | 2.40437625 |
| 54 | Amyloidosis (HP:0011034) | 2.36261853 |
| 55 | Keratitis (HP:0000491) | 2.33525640 |
| 56 | Aplasia/Hypoplasia of the macula (HP:0008059) | 2.33305977 |
| 57 | Vertigo (HP:0002321) | 2.31019914 |
| 58 | Hypochromic anemia (HP:0001931) | 2.30578991 |
| 59 | Acute hepatic failure (HP:0006554) | 2.26062998 |
| 60 | Cheilitis (HP:0100825) | 2.24468221 |
| 61 | Sepsis (HP:0100806) | 2.17811012 |
| 62 | Inflammation of the large intestine (HP:0002037) | 2.17025958 |
| 63 | Choroideremia (HP:0001139) | 2.15167799 |
| 64 | Petechiae (HP:0000967) | 2.14651974 |
| 65 | Glomerulopathy (HP:0100820) | 2.14099632 |
| 66 | Increased IgM level (HP:0003496) | 2.12982233 |
| 67 | Osteomyelitis (HP:0002754) | 2.12812136 |
| 68 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 2.12373493 |
| 69 | Granulocytopenia (HP:0001913) | 2.08978460 |
| 70 | Eosinophilia (HP:0001880) | 2.08567716 |
| 71 | Difficulty running (HP:0009046) | 2.05413040 |
| 72 | Postural instability (HP:0002172) | 2.03069024 |
| 73 | Ocular albinism (HP:0001107) | 2.01026653 |
| 74 | Abnormal platelet volume (HP:0011876) | 1.98554892 |
| 75 | Viral hepatitis (HP:0006562) | 1.97270286 |
| 76 | Thrombophlebitis (HP:0004418) | 1.94691142 |
| 77 | Gastrointestinal inflammation (HP:0004386) | 1.94060348 |
| 78 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.91859896 |
| 79 | Absent/shortened dynein arms (HP:0200106) | 1.91859896 |
| 80 | Abnormality of T cell physiology (HP:0011840) | 1.86456703 |
| 81 | Recurrent viral infections (HP:0004429) | 1.86093117 |
| 82 | Papillary thyroid carcinoma (HP:0002895) | 1.79693877 |
| 83 | Acne (HP:0001061) | 1.78615455 |
| 84 | Abnormality of the pericardium (HP:0001697) | 1.78583488 |
| 85 | Autoimmune hemolytic anemia (HP:0001890) | 1.78321510 |
| 86 | Neurodegeneration (HP:0002180) | 1.76663647 |
| 87 | Joint swelling (HP:0001386) | 1.76421161 |
| 88 | Microcytic anemia (HP:0001935) | 1.76127480 |
| 89 | Stomach cancer (HP:0012126) | 1.76009299 |
| 90 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.72842053 |
| 91 | Abnormality of eosinophils (HP:0001879) | 1.72459290 |
| 92 | Autoimmune thrombocytopenia (HP:0001973) | 1.72277942 |
| 93 | Resting tremor (HP:0002322) | 1.70882792 |
| 94 | Chronic otitis media (HP:0000389) | 1.70415099 |
| 95 | Polyneuropathy (HP:0001271) | 1.70261766 |
| 96 | Menorrhagia (HP:0000132) | 1.68761929 |
| 97 | Onion bulb formation (HP:0003383) | 1.67768430 |
| 98 | Skin ulcer (HP:0200042) | 1.66354922 |
| 99 | Recurrent pneumonia (HP:0006532) | 1.66344950 |
| 100 | Skin rash (HP:0000988) | 1.63928343 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.90583217 |
| 2 | IRAK4 | 3.55972679 |
| 3 | BLK | 3.55657728 |
| 4 | MAP2K3 | 2.89772020 |
| 5 | CSK | 2.68273763 |
| 6 | TYK2 | 2.39777045 |
| 7 | EPHB1 | 2.34491143 |
| 8 | FES | 2.26121477 |
| 9 | ZAP70 | 2.04219382 |
| 10 | MAP3K2 | 1.99330001 |
| 11 | GRK6 | 1.95886060 |
| 12 | MAP4K1 | 1.95796595 |
| 13 | IRAK1 | 1.88905472 |
| 14 | FGR | 1.85515476 |
| 15 | TXK | 1.85194533 |
| 16 | BTK | 1.84584617 |
| 17 | TNK2 | 1.83582061 |
| 18 | SIK2 | 1.82310799 |
| 19 | TAOK3 | 1.81376704 |
| 20 | JAK2 | 1.81172179 |
| 21 | HCK | 1.80451183 |
| 22 | KSR2 | 1.71505914 |
| 23 | SYK | 1.63393851 |
| 24 | YES1 | 1.62915991 |
| 25 | ERN1 | 1.61783138 |
| 26 | PIK3CG | 1.57676799 |
| 27 | MAP3K6 | 1.52844894 |
| 28 | FRK | 1.52546413 |
| 29 | IRAK2 | 1.50229322 |
| 30 | JAK3 | 1.47680054 |
| 31 | LYN | 1.41025720 |
| 32 | IKBKE | 1.39101708 |
| 33 | TAOK1 | 1.36305176 |
| 34 | MARK3 | 1.35923949 |
| 35 | MAP3K3 | 1.30021173 |
| 36 | JAK1 | 1.29150943 |
| 37 | MAP3K1 | 1.19857395 |
| 38 | PTK2B | 1.18578962 |
| 39 | BMPR2 | 1.13228187 |
| 40 | RAF1 | 1.11262144 |
| 41 | WNK1 | 1.10999182 |
| 42 | MAP2K4 | 1.09794016 |
| 43 | MATK | 1.08593913 |
| 44 | TEC | 1.04689229 |
| 45 | MAP3K11 | 1.01960578 |
| 46 | CDK19 | 0.97263242 |
| 47 | KSR1 | 0.95520068 |
| 48 | LCK | 0.95277969 |
| 49 | MAP3K14 | 0.91657081 |
| 50 | ITK | 0.89473974 |
| 51 | ACVR1B | 0.88354281 |
| 52 | FGFR3 | 0.86995965 |
| 53 | DAPK2 | 0.86506779 |
| 54 | SIK3 | 0.85891320 |
| 55 | MARK2 | 0.85609824 |
| 56 | LRRK2 | 0.82670619 |
| 57 | MAP3K5 | 0.82331374 |
| 58 | NTRK3 | 0.81446689 |
| 59 | SGK2 | 0.81038204 |
| 60 | TGFBR2 | 0.80978147 |
| 61 | CSF1R | 0.78491524 |
| 62 | EPHA3 | 0.77871746 |
| 63 | PRKCH | 0.77017967 |
| 64 | SGK3 | 0.75435182 |
| 65 | FYN | 0.74445709 |
| 66 | PDK1 | 0.73651603 |
| 67 | RET | 0.72754287 |
| 68 | STK11 | 0.71955373 |
| 69 | KIT | 0.71842788 |
| 70 | OXSR1 | 0.71449533 |
| 71 | PAK3 | 0.69558625 |
| 72 | MAP2K6 | 0.67666973 |
| 73 | PTK6 | 0.67229976 |
| 74 | STK38 | 0.65747797 |
| 75 | TBK1 | 0.64638297 |
| 76 | DYRK1B | 0.59354287 |
| 77 | DYRK3 | 0.55099985 |
| 78 | PDPK1 | 0.54503295 |
| 79 | PRKCZ | 0.51719081 |
| 80 | ERBB2 | 0.46971685 |
| 81 | CAMKK2 | 0.45528180 |
| 82 | MAP3K7 | 0.42986037 |
| 83 | NLK | 0.40618851 |
| 84 | SGK223 | 0.40341951 |
| 85 | SGK494 | 0.40341951 |
| 86 | PRKD2 | 0.40111999 |
| 87 | PRKD1 | 0.36828701 |
| 88 | EGFR | 0.35870119 |
| 89 | IKBKB | 0.35404149 |
| 90 | PRKCQ | 0.34677876 |
| 91 | PRPF4B | 0.34375414 |
| 92 | ADRBK1 | 0.33102479 |
| 93 | DYRK1A | 0.32564329 |
| 94 | STK10 | 0.32241443 |
| 95 | MAPKAPK2 | 0.31092637 |
| 96 | BCR | 0.31018461 |
| 97 | CAMK4 | 0.30252260 |
| 98 | SGK1 | 0.29521975 |
| 99 | DMPK | 0.28817356 |
| 100 | PIM1 | 0.28193027 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Leishmaniasis_Homo sapiens_hsa05140 | 2.94371637 |
| 2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.82702822 |
| 3 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.55527464 |
| 4 | Tuberculosis_Homo sapiens_hsa05152 | 2.30297562 |
| 5 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.26929440 |
| 6 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.24596194 |
| 7 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.21394862 |
| 8 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.16371648 |
| 9 | Legionellosis_Homo sapiens_hsa05134 | 2.00374956 |
| 10 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.93570134 |
| 11 | Measles_Homo sapiens_hsa05162 | 1.86678031 |
| 12 | Malaria_Homo sapiens_hsa05144 | 1.80235417 |
| 13 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.77508173 |
| 14 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.75884928 |
| 15 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.75210639 |
| 16 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.62759891 |
| 17 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.51332856 |
| 18 | Platelet activation_Homo sapiens_hsa04611 | 1.48552912 |
| 19 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.46092529 |
| 20 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.44878657 |
| 21 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.40213106 |
| 22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.39161161 |
| 23 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.38799702 |
| 24 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.38232813 |
| 25 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.38101932 |
| 26 | Phagosome_Homo sapiens_hsa04145 | 1.36268214 |
| 27 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.33611060 |
| 28 | Influenza A_Homo sapiens_hsa05164 | 1.31989128 |
| 29 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.31485540 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.29601262 |
| 31 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.28459897 |
| 32 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.24442223 |
| 33 | Hepatitis B_Homo sapiens_hsa05161 | 1.23990238 |
| 34 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.19200796 |
| 35 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.18203860 |
| 36 | Allograft rejection_Homo sapiens_hsa05330 | 1.17734671 |
| 37 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.11596986 |
| 38 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.09185608 |
| 39 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.08119341 |
| 40 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.03852820 |
| 41 | Salmonella infection_Homo sapiens_hsa05132 | 1.02431188 |
| 42 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.01988190 |
| 43 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.01493581 |
| 44 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.99734315 |
| 45 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.96242357 |
| 46 | Hepatitis C_Homo sapiens_hsa05160 | 0.95743359 |
| 47 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.94983693 |
| 48 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.94382903 |
| 49 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.90878553 |
| 50 | Apoptosis_Homo sapiens_hsa04210 | 0.89642352 |
| 51 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.87741489 |
| 52 | Pertussis_Homo sapiens_hsa05133 | 0.87108528 |
| 53 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.85773802 |
| 54 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.84380975 |
| 55 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.83216907 |
| 56 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.81010413 |
| 57 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.80059248 |
| 58 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.78920638 |
| 59 | Shigellosis_Homo sapiens_hsa05131 | 0.78085894 |
| 60 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.77879902 |
| 61 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.76951877 |
| 62 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.76423462 |
| 63 | Endometrial cancer_Homo sapiens_hsa05213 | 0.75362618 |
| 64 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.74298544 |
| 65 | Viral myocarditis_Homo sapiens_hsa05416 | 0.74066274 |
| 66 | Endocytosis_Homo sapiens_hsa04144 | 0.73551518 |
| 67 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.72170604 |
| 68 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.71206661 |
| 69 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.70890024 |
| 70 | Morphine addiction_Homo sapiens_hsa05032 | 0.70719056 |
| 71 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.69415317 |
| 72 | Prostate cancer_Homo sapiens_hsa05215 | 0.68932583 |
| 73 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.67817284 |
| 74 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.67190734 |
| 75 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.65955032 |
| 76 | Amoebiasis_Homo sapiens_hsa05146 | 0.64979131 |
| 77 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.63204986 |
| 78 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.61647020 |
| 79 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.61046447 |
| 80 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.60588037 |
| 81 | Insulin resistance_Homo sapiens_hsa04931 | 0.59268440 |
| 82 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.59097566 |
| 83 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.57922097 |
| 84 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.57687868 |
| 85 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.56803085 |
| 86 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.56619936 |
| 87 | Glioma_Homo sapiens_hsa05214 | 0.56189178 |
| 88 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.54378351 |
| 89 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.54208230 |
| 90 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.51574589 |
| 91 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.51526140 |
| 92 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.49695978 |
| 93 | Colorectal cancer_Homo sapiens_hsa05210 | 0.49560280 |
| 94 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.48601304 |
| 95 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.46095357 |
| 96 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.45765578 |
| 97 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.45380876 |
| 98 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.44779480 |
| 99 | Long-term potentiation_Homo sapiens_hsa04720 | 0.44010219 |
| 100 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.43392265 |

