

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | chemosensory behavior (GO:0007635) | 9.37482613 |
| 2 | spermatid nucleus differentiation (GO:0007289) | 5.74024128 |
| 3 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 5.46295247 |
| 4 | mitochondrial DNA metabolic process (GO:0032042) | 4.89524408 |
| 5 | detection of chemical stimulus involved in sensory perception of taste (GO:0050912) | 4.75438423 |
| 6 | retinal rod cell development (GO:0046548) | 4.49528094 |
| 7 | tRNA aminoacylation for protein translation (GO:0006418) | 4.48821851 |
| 8 | amino acid activation (GO:0043038) | 4.40426524 |
| 9 | tRNA aminoacylation (GO:0043039) | 4.40426524 |
| 10 | nuclear pore complex assembly (GO:0051292) | 4.26440349 |
| 11 | mitochondrial DNA replication (GO:0006264) | 4.19975846 |
| 12 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 4.18810985 |
| 13 | L-serine metabolic process (GO:0006563) | 4.06382411 |
| 14 | glucose 6-phosphate metabolic process (GO:0051156) | 4.06232843 |
| 15 | retinal cone cell development (GO:0046549) | 4.05557132 |
| 16 | mitotic sister chromatid cohesion (GO:0007064) | 4.04283306 |
| 17 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.98607798 |
| 18 | DNA strand elongation (GO:0022616) | 3.79132524 |
| 19 | sensory perception of taste (GO:0050909) | 3.78014188 |
| 20 | negative regulation of DNA recombination (GO:0045910) | 3.77882972 |
| 21 | ER overload response (GO:0006983) | 3.76970144 |
| 22 | succinate metabolic process (GO:0006105) | 3.76729995 |
| 23 | regulation of mitotic spindle organization (GO:0060236) | 3.74171644 |
| 24 | chromatin remodeling at centromere (GO:0031055) | 3.72338356 |
| 25 | CENP-A containing nucleosome assembly (GO:0034080) | 3.67188013 |
| 26 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 3.66028473 |
| 27 | acrosome assembly (GO:0001675) | 3.63565915 |
| 28 | gluconeogenesis (GO:0006094) | 3.61249563 |
| 29 | nuclear pore organization (GO:0006999) | 3.59422698 |
| 30 | histone mRNA catabolic process (GO:0071044) | 3.59060674 |
| 31 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.57980938 |
| 32 | spindle checkpoint (GO:0031577) | 3.57175886 |
| 33 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.55547588 |
| 34 | negative regulation of sister chromatid segregation (GO:0033046) | 3.55547588 |
| 35 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.55547588 |
| 36 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.55547588 |
| 37 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.55547588 |
| 38 | glycolytic process (GO:0006096) | 3.54351735 |
| 39 | protein localization to kinetochore (GO:0034501) | 3.54292675 |
| 40 | mitotic spindle checkpoint (GO:0071174) | 3.54127098 |
| 41 | hexose biosynthetic process (GO:0019319) | 3.49493976 |
| 42 | cullin deneddylation (GO:0010388) | 3.46977546 |
| 43 | negative regulation of chromosome segregation (GO:0051985) | 3.46149192 |
| 44 | DNA strand renaturation (GO:0000733) | 3.44997982 |
| 45 | regulation of centriole replication (GO:0046599) | 3.44159929 |
| 46 | telomere maintenance via recombination (GO:0000722) | 3.43446990 |
| 47 | histone exchange (GO:0043486) | 3.41394180 |
| 48 | DNA replication checkpoint (GO:0000076) | 3.40547509 |
| 49 | non-recombinational repair (GO:0000726) | 3.39672670 |
| 50 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.39672670 |
| 51 | inner cell mass cell proliferation (GO:0001833) | 3.36532039 |
| 52 | mitotic G2/M transition checkpoint (GO:0044818) | 3.31767308 |
| 53 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.31269890 |
| 54 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.31269890 |
| 55 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.27209896 |
| 56 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.27209896 |
| 57 | protein K11-linked deubiquitination (GO:0035871) | 3.27140587 |
| 58 | DNA ligation (GO:0006266) | 3.25036624 |
| 59 | mitotic recombination (GO:0006312) | 3.24362567 |
| 60 | mitotic nuclear envelope disassembly (GO:0007077) | 3.24230062 |
| 61 | monosaccharide biosynthetic process (GO:0046364) | 3.23615187 |
| 62 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.21488376 |
| 63 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.21488376 |
| 64 | regulation of sister chromatid segregation (GO:0033045) | 3.21488376 |
| 65 | L-alpha-amino acid transmembrane transport (GO:1902475) | 3.20979970 |
| 66 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.18414765 |
| 67 | aldehyde catabolic process (GO:0046185) | 3.18126361 |
| 68 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.16178693 |
| 69 | mitotic G2 DNA damage checkpoint (GO:0007095) | 3.15860027 |
| 70 | mitotic sister chromatid segregation (GO:0000070) | 3.15167649 |
| 71 | sister chromatid segregation (GO:0000819) | 3.13007523 |
| 72 | protein deneddylation (GO:0000338) | 3.12749306 |
| 73 | spindle assembly checkpoint (GO:0071173) | 3.12422781 |
| 74 | neural tube formation (GO:0001841) | 3.11556805 |
| 75 | regulation of spindle organization (GO:0090224) | 3.09925735 |
| 76 | DNA replication initiation (GO:0006270) | 3.09394451 |
| 77 | response to nitrosative stress (GO:0051409) | 3.08991566 |
| 78 | pore complex assembly (GO:0046931) | 3.08738828 |
| 79 | formation of translation preinitiation complex (GO:0001731) | 3.08223521 |
| 80 | DNA unwinding involved in DNA replication (GO:0006268) | 3.07314687 |
| 81 | histone H2A acetylation (GO:0043968) | 3.04656573 |
| 82 | membrane disassembly (GO:0030397) | 3.03259274 |
| 83 | nuclear envelope disassembly (GO:0051081) | 3.03259274 |
| 84 | DNA damage response, detection of DNA damage (GO:0042769) | 3.01707414 |
| 85 | poly(A)+ mRNA export from nucleus (GO:0016973) | 3.00645458 |
| 86 | mitotic spindle assembly checkpoint (GO:0007094) | 2.99782927 |
| 87 | nonmotile primary cilium assembly (GO:0035058) | 2.99228873 |
| 88 | endosome to pigment granule transport (GO:0043485) | 2.98584916 |
| 89 | endosome to melanosome transport (GO:0035646) | 2.98584916 |
| 90 | fructose metabolic process (GO:0006000) | 2.98222030 |
| 91 | maintenance of protein location in nucleus (GO:0051457) | 2.96753337 |
| 92 | replication fork processing (GO:0031297) | 2.95818368 |
| 93 | regulation of translational fidelity (GO:0006450) | 2.95340516 |
| 94 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.93669205 |
| 95 | IMP biosynthetic process (GO:0006188) | 2.93417745 |
| 96 | negative regulation of histone acetylation (GO:0035067) | 2.92948519 |
| 97 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.91677404 |
| 98 | DNA replication-independent nucleosome organization (GO:0034724) | 2.91677404 |
| 99 | DNA double-strand break processing (GO:0000729) | 2.89914274 |
| 100 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.86880620 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.00148469 |
| 2 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.04706317 |
| 3 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.73446221 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.66885582 |
| 5 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.19683243 |
| 6 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 3.10697291 |
| 7 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.96896138 |
| 8 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.94550862 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.94313580 |
| 10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.79109441 |
| 11 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.76546150 |
| 12 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.67753262 |
| 13 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.49393598 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.25433128 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.15196800 |
| 16 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.13824754 |
| 17 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.10020041 |
| 18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.08816648 |
| 19 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.97851937 |
| 20 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.93844393 |
| 21 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.92387894 |
| 22 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.91487300 |
| 23 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.90990034 |
| 24 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.89451738 |
| 25 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.82597683 |
| 26 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.82487402 |
| 27 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.80135648 |
| 28 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.75049260 |
| 29 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.70166107 |
| 30 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.69164263 |
| 31 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.67944204 |
| 32 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.57523603 |
| 33 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.56247722 |
| 34 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.55483694 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.54684612 |
| 36 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.52668376 |
| 37 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.51444763 |
| 38 | GATA1_22025678_ChIP-Seq_K562_Human | 1.49795228 |
| 39 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.47214637 |
| 40 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.46974210 |
| 41 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.46643327 |
| 42 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.46043237 |
| 43 | VDR_22108803_ChIP-Seq_LS180_Human | 1.45174956 |
| 44 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.43244042 |
| 45 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.42875491 |
| 46 | EWS_26573619_Chip-Seq_HEK293_Human | 1.42660568 |
| 47 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.41181166 |
| 48 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.40712090 |
| 49 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.36571185 |
| 50 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.34699639 |
| 51 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.31290589 |
| 52 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.29156565 |
| 53 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.25575696 |
| 54 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.22172571 |
| 55 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.21454659 |
| 56 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.16070240 |
| 57 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.13511904 |
| 58 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.11969523 |
| 59 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.11271300 |
| 60 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.09921734 |
| 61 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.09610457 |
| 62 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.08915780 |
| 63 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.08802705 |
| 64 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.07960746 |
| 65 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.05028328 |
| 66 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.00391351 |
| 67 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.98446226 |
| 68 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.98426858 |
| 69 | FUS_26573619_Chip-Seq_HEK293_Human | 0.97723172 |
| 70 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.94020671 |
| 71 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.93820335 |
| 72 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.92406001 |
| 73 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.91513663 |
| 74 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.91495713 |
| 75 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.91020827 |
| 76 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.90659895 |
| 77 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.90164470 |
| 78 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.89760282 |
| 79 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.88532428 |
| 80 | P300_19829295_ChIP-Seq_ESCs_Human | 0.88507740 |
| 81 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.87791642 |
| 82 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.87686422 |
| 83 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.85580448 |
| 84 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.85267355 |
| 85 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.85250574 |
| 86 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.85170499 |
| 87 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.85066714 |
| 88 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.84663251 |
| 89 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.84391782 |
| 90 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.84287710 |
| 91 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.82722766 |
| 92 | STAT3_23295773_ChIP-Seq_U87_Human | 0.81795910 |
| 93 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.81680871 |
| 94 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.80235448 |
| 95 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.78863229 |
| 96 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.78595566 |
| 97 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.78224864 |
| 98 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.77930293 |
| 99 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.76581668 |
| 100 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.76091027 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008057_abnormal_DNA_replication | 5.80602041 |
| 2 | MP0008007_abnormal_cellular_replicative | 4.58704821 |
| 3 | MP0010094_abnormal_chromosome_stability | 4.15804303 |
| 4 | MP0008058_abnormal_DNA_repair | 3.49054621 |
| 5 | MP0003077_abnormal_cell_cycle | 3.15272841 |
| 6 | MP0003111_abnormal_nucleus_morphology | 3.03082039 |
| 7 | MP0002009_preneoplasia | 2.76578036 |
| 8 | MP0003195_calcinosis | 2.50402764 |
| 9 | MP0009697_abnormal_copulation | 2.49506911 |
| 10 | MP0004957_abnormal_blastocyst_morpholog | 2.45522836 |
| 11 | MP0003786_premature_aging | 2.32939140 |
| 12 | MP0008932_abnormal_embryonic_tissue | 2.26432819 |
| 13 | MP0003656_abnormal_erythrocyte_physiolo | 2.24935574 |
| 14 | MP0001529_abnormal_vocalization | 2.19283519 |
| 15 | MP0006292_abnormal_olfactory_placode | 2.16142919 |
| 16 | MP0004147_increased_porphyrin_level | 2.09051896 |
| 17 | MP0003693_abnormal_embryo_hatching | 2.08488541 |
| 18 | MP0003122_maternal_imprinting | 1.86691803 |
| 19 | MP0003567_abnormal_fetal_cardiomyocyte | 1.84298660 |
| 20 | MP0000566_synostosis | 1.82329705 |
| 21 | MP0000579_abnormal_nail_morphology | 1.76007624 |
| 22 | MP0000647_abnormal_sebaceous_gland | 1.75876421 |
| 23 | MP0002938_white_spotting | 1.73427607 |
| 24 | MP0006035_abnormal_mitochondrial_morpho | 1.65479527 |
| 25 | MP0010307_abnormal_tumor_latency | 1.61666475 |
| 26 | MP0002132_abnormal_respiratory_system | 1.48969830 |
| 27 | MP0002090_abnormal_vision | 1.45192176 |
| 28 | MP0001764_abnormal_homeostasis | 1.41433699 |
| 29 | MP0001697_abnormal_embryo_size | 1.39757070 |
| 30 | MP0004264_abnormal_extraembryonic_tissu | 1.34153487 |
| 31 | MP0000427_abnormal_hair_cycle | 1.33510631 |
| 32 | MP0003252_abnormal_bile_duct | 1.33284104 |
| 33 | MP0005451_abnormal_body_composition | 1.32740523 |
| 34 | MP0010352_gastrointestinal_tract_polyps | 1.29721447 |
| 35 | MP0001929_abnormal_gametogenesis | 1.29628879 |
| 36 | MP0001672_abnormal_embryogenesis/_devel | 1.27657330 |
| 37 | MP0005380_embryogenesis_phenotype | 1.27657330 |
| 38 | MP0010329_abnormal_lipoprotein_level | 1.26948565 |
| 39 | MP0002751_abnormal_autonomic_nervous | 1.24164216 |
| 40 | MP0005174_abnormal_tail_pigmentation | 1.22987305 |
| 41 | MP0003937_abnormal_limbs/digits/tail_de | 1.22257151 |
| 42 | MP0003984_embryonic_growth_retardation | 1.14134412 |
| 43 | MP0008877_abnormal_DNA_methylation | 1.14121817 |
| 44 | MP0001324_abnormal_eye_pigmentation | 1.12322811 |
| 45 | MP0002088_abnormal_embryonic_growth/wei | 1.12173861 |
| 46 | MP0009703_decreased_birth_body | 1.09144128 |
| 47 | MP0002095_abnormal_skin_pigmentation | 1.08376739 |
| 48 | MP0005394_taste/olfaction_phenotype | 1.07849699 |
| 49 | MP0005499_abnormal_olfactory_system | 1.07849699 |
| 50 | MP0002080_prenatal_lethality | 1.07669164 |
| 51 | MP0000350_abnormal_cell_proliferation | 1.06495916 |
| 52 | MP0008789_abnormal_olfactory_epithelium | 1.05843441 |
| 53 | MP0001293_anophthalmia | 1.03835366 |
| 54 | MP0001730_embryonic_growth_arrest | 1.02979315 |
| 55 | MP0004197_abnormal_fetal_growth/weight/ | 1.02763772 |
| 56 | MP0003183_abnormal_peptide_metabolism | 1.01687802 |
| 57 | MP0003941_abnormal_skin_development | 1.00019800 |
| 58 | MP0002084_abnormal_developmental_patter | 0.98207774 |
| 59 | MP0005266_abnormal_metabolism | 0.97588453 |
| 60 | MP0005408_hypopigmentation | 0.91715581 |
| 61 | MP0005171_absent_coat_pigmentation | 0.91135629 |
| 62 | MP0009672_abnormal_birth_weight | 0.90621013 |
| 63 | MP0002160_abnormal_reproductive_system | 0.88887562 |
| 64 | MP0005253_abnormal_eye_physiology | 0.87640463 |
| 65 | MP0005310_abnormal_salivary_gland | 0.84483061 |
| 66 | MP0003806_abnormal_nucleotide_metabolis | 0.83809131 |
| 67 | MP0002086_abnormal_extraembryonic_tissu | 0.82656817 |
| 68 | MP0003121_genomic_imprinting | 0.80906606 |
| 69 | MP0000358_abnormal_cell_content/ | 0.80741311 |
| 70 | MP0001661_extended_life_span | 0.80370649 |
| 71 | MP0003698_abnormal_male_reproductive | 0.79672344 |
| 72 | MP0002928_abnormal_bile_duct | 0.79122310 |
| 73 | MP0002085_abnormal_embryonic_tissue | 0.78654837 |
| 74 | MP0003221_abnormal_cardiomyocyte_apopto | 0.77719378 |
| 75 | MP0000653_abnormal_sex_gland | 0.77554247 |
| 76 | MP0002697_abnormal_eye_size | 0.77119845 |
| 77 | MP0004134_abnormal_chest_morphology | 0.76708902 |
| 78 | MP0008872_abnormal_physiological_respon | 0.74375325 |
| 79 | MP0002111_abnormal_tail_morphology | 0.74100366 |
| 80 | MP0009780_abnormal_chondrocyte_physiolo | 0.73242527 |
| 81 | MP0002127_abnormal_cardiovascular_syste | 0.72657969 |
| 82 | MP0005376_homeostasis/metabolism_phenot | 0.71962579 |
| 83 | MP0000313_abnormal_cell_death | 0.71666305 |
| 84 | MP0000383_abnormal_hair_follicle | 0.70686466 |
| 85 | MP0002210_abnormal_sex_determination | 0.70432614 |
| 86 | MP0002075_abnormal_coat/hair_pigmentati | 0.70262008 |
| 87 | MP0000015_abnormal_ear_pigmentation | 0.70192965 |
| 88 | MP0000569_abnormal_digit_pigmentation | 0.69468503 |
| 89 | MP0005551_abnormal_eye_electrophysiolog | 0.68173529 |
| 90 | MP0001145_abnormal_male_reproductive | 0.68096043 |
| 91 | MP0006072_abnormal_retinal_apoptosis | 0.67263503 |
| 92 | MP0002233_abnormal_nose_morphology | 0.67236596 |
| 93 | MP0010678_abnormal_skin_adnexa | 0.66410316 |
| 94 | MP0003890_abnormal_embryonic-extraembry | 0.66262110 |
| 95 | MP0002168_other_aberrant_phenotype | 0.66244342 |
| 96 | MP0003878_abnormal_ear_physiology | 0.64561195 |
| 97 | MP0005377_hearing/vestibular/ear_phenot | 0.64561195 |
| 98 | MP0005332_abnormal_amino_acid | 0.63252615 |
| 99 | MP0001286_abnormal_eye_development | 0.63055077 |
| 100 | MP0003283_abnormal_digestive_organ | 0.62652314 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Cholecystitis (HP:0001082) | 9.46916053 |
| 2 | Abnormal gallbladder physiology (HP:0012438) | 9.46916053 |
| 3 | Hypoplastic pelvis (HP:0008839) | 6.06660633 |
| 4 | Stenosis of the external auditory canal (HP:0000402) | 3.48883217 |
| 5 | Abnormal gallbladder morphology (HP:0012437) | 3.47233635 |
| 6 | Cholelithiasis (HP:0001081) | 3.39219070 |
| 7 | Neonatal respiratory distress (HP:0002643) | 3.32562077 |
| 8 | Abnormality of glycolysis (HP:0004366) | 3.31817315 |
| 9 | Rhabdomyosarcoma (HP:0002859) | 3.29039100 |
| 10 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.20118794 |
| 11 | Poor eye contact (HP:0000817) | 3.19831106 |
| 12 | Impaired proprioception (HP:0010831) | 3.12920988 |
| 13 | Colon cancer (HP:0003003) | 2.98874135 |
| 14 | Testicular atrophy (HP:0000029) | 2.90814905 |
| 15 | Postnatal microcephaly (HP:0005484) | 2.88541236 |
| 16 | Delayed puberty (HP:0000823) | 2.86410471 |
| 17 | Abnormality of chromosome stability (HP:0003220) | 2.84768289 |
| 18 | Prolonged partial thromboplastin time (HP:0003645) | 2.80935729 |
| 19 | Impaired social interactions (HP:0000735) | 2.72746323 |
| 20 | Abnormal social behavior (HP:0012433) | 2.72746323 |
| 21 | Abnormality of the metopic suture (HP:0005556) | 2.57873928 |
| 22 | Overlapping toe (HP:0001845) | 2.57838917 |
| 23 | Facial hemangioma (HP:0000329) | 2.56836773 |
| 24 | Chromsome breakage (HP:0040012) | 2.53758562 |
| 25 | Insidious onset (HP:0003587) | 2.47283496 |
| 26 | Termporal pattern (HP:0011008) | 2.47283496 |
| 27 | Homocystinuria (HP:0002156) | 2.46740642 |
| 28 | Abnormality of homocysteine metabolism (HP:0010919) | 2.46740642 |
| 29 | Abnormal lung lobation (HP:0002101) | 2.46107211 |
| 30 | Sloping forehead (HP:0000340) | 2.39477238 |
| 31 | Duodenal stenosis (HP:0100867) | 2.37945216 |
| 32 | Small intestinal stenosis (HP:0012848) | 2.37945216 |
| 33 | Meckel diverticulum (HP:0002245) | 2.34620877 |
| 34 | Abnormality of macular pigmentation (HP:0008002) | 2.32784844 |
| 35 | Increased density of long bones (HP:0006392) | 2.32613249 |
| 36 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.31568169 |
| 37 | Neoplasm of striated muscle (HP:0009728) | 2.24203359 |
| 38 | Neoplasm of the colon (HP:0100273) | 2.22871101 |
| 39 | 11 pairs of ribs (HP:0000878) | 2.22748596 |
| 40 | Megaloblastic anemia (HP:0001889) | 2.22189626 |
| 41 | Adrenal hypoplasia (HP:0000835) | 2.21675340 |
| 42 | Progressive external ophthalmoplegia (HP:0000590) | 2.20800514 |
| 43 | Entropion (HP:0000621) | 2.17759527 |
| 44 | Ulnar claw (HP:0001178) | 2.16622375 |
| 45 | Abnormality of the ileum (HP:0001549) | 2.15484102 |
| 46 | Abnormality of the preputium (HP:0100587) | 2.12562094 |
| 47 | Decreased testicular size (HP:0008734) | 2.10910020 |
| 48 | Delayed epiphyseal ossification (HP:0002663) | 2.10710562 |
| 49 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.10506587 |
| 50 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.10506587 |
| 51 | Abnormality of the duodenum (HP:0002246) | 2.10118920 |
| 52 | Abnormality of the gallbladder (HP:0005264) | 2.09822570 |
| 53 | Abnormality of the carotid arteries (HP:0005344) | 2.09119100 |
| 54 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.07425225 |
| 55 | Proximal amyotrophy (HP:0007126) | 2.04465613 |
| 56 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.02889330 |
| 57 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.02889330 |
| 58 | Hyperventilation (HP:0002883) | 2.02884564 |
| 59 | Prominent metopic ridge (HP:0005487) | 2.02396002 |
| 60 | Global brain atrophy (HP:0002283) | 1.98510555 |
| 61 | Dyschromatopsia (HP:0007641) | 1.98087984 |
| 62 | Oligodactyly (HP:0012165) | 1.96707782 |
| 63 | Embryonal renal neoplasm (HP:0011794) | 1.96665547 |
| 64 | Poor coordination (HP:0002370) | 1.96574714 |
| 65 | Abnormality of chromosome segregation (HP:0002916) | 1.96037946 |
| 66 | Medulloblastoma (HP:0002885) | 1.93348556 |
| 67 | Rib fusion (HP:0000902) | 1.92439530 |
| 68 | Congenital primary aphakia (HP:0007707) | 1.92388861 |
| 69 | Nephrogenic diabetes insipidus (HP:0009806) | 1.89390937 |
| 70 | Shoulder girdle muscle weakness (HP:0003547) | 1.88891618 |
| 71 | Pelvic girdle muscle weakness (HP:0003749) | 1.88577848 |
| 72 | Supernumerary spleens (HP:0009799) | 1.88480825 |
| 73 | Ectopic kidney (HP:0000086) | 1.87428364 |
| 74 | Acute hepatic failure (HP:0006554) | 1.87005188 |
| 75 | Diastasis recti (HP:0001540) | 1.86481089 |
| 76 | Abnormality of methionine metabolism (HP:0010901) | 1.85514490 |
| 77 | Hypobetalipoproteinemia (HP:0003563) | 1.84532998 |
| 78 | Poikiloderma (HP:0001029) | 1.83754530 |
| 79 | Upper limb muscle weakness (HP:0003484) | 1.83221493 |
| 80 | Oligodactyly (hands) (HP:0001180) | 1.83046987 |
| 81 | Anhidrosis (HP:0000970) | 1.82067711 |
| 82 | Chorioretinal coloboma (HP:0000567) | 1.79934177 |
| 83 | Duplicated collecting system (HP:0000081) | 1.79152719 |
| 84 | Hypogonadotrophic hypogonadism (HP:0000044) | 1.78744675 |
| 85 | Progressive inability to walk (HP:0002505) | 1.77604847 |
| 86 | Cone-rod dystrophy (HP:0000548) | 1.77012966 |
| 87 | Myelodysplasia (HP:0002863) | 1.76891873 |
| 88 | Abnormality of the intrinsic pathway (HP:0010989) | 1.76407669 |
| 89 | Gait imbalance (HP:0002141) | 1.76189144 |
| 90 | Hypoplastic female external genitalia (HP:0012815) | 1.75375154 |
| 91 | Hyperglycemia (HP:0003074) | 1.69964270 |
| 92 | Genital tract atresia (HP:0001827) | 1.69677202 |
| 93 | Retinal atrophy (HP:0001105) | 1.69351725 |
| 94 | Clubbing of toes (HP:0100760) | 1.69099708 |
| 95 | Progressive sensorineural hearing impairment (HP:0000408) | 1.68214068 |
| 96 | Labial hypoplasia (HP:0000066) | 1.66884411 |
| 97 | Vaginal atresia (HP:0000148) | 1.65184971 |
| 98 | Progressive hearing impairment (HP:0001730) | 1.63772393 |
| 99 | Missing ribs (HP:0000921) | 1.63127258 |
| 100 | Hypopigmentation of the fundus (HP:0007894) | 1.63103989 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EIF2AK1 | 4.74197311 |
| 2 | BUB1 | 4.64412559 |
| 3 | TTK | 3.18911390 |
| 4 | MKNK2 | 3.11127068 |
| 5 | PASK | 2.94734632 |
| 6 | TSSK6 | 2.79304484 |
| 7 | TAOK3 | 2.70506953 |
| 8 | MKNK1 | 2.66103309 |
| 9 | NEK9 | 2.36576302 |
| 10 | WNK3 | 2.34617296 |
| 11 | EIF2AK3 | 2.18543663 |
| 12 | BRD4 | 2.15154535 |
| 13 | PLK4 | 2.15123583 |
| 14 | FRK | 2.09523963 |
| 15 | PLK3 | 2.08623566 |
| 16 | NEK1 | 1.97798509 |
| 17 | STK16 | 1.82200155 |
| 18 | NUAK1 | 1.79355046 |
| 19 | WEE1 | 1.79050124 |
| 20 | PLK1 | 1.76375411 |
| 21 | TNIK | 1.64190466 |
| 22 | STK39 | 1.59587844 |
| 23 | TRIM28 | 1.54916832 |
| 24 | BRSK2 | 1.49738903 |
| 25 | NLK | 1.40521361 |
| 26 | ATR | 1.39950356 |
| 27 | PDK2 | 1.33735563 |
| 28 | PLK2 | 1.33642834 |
| 29 | ZAK | 1.30464126 |
| 30 | PBK | 1.22858412 |
| 31 | FGFR2 | 1.22375599 |
| 32 | TRPM7 | 1.22268594 |
| 33 | ERBB3 | 1.21910262 |
| 34 | WNK4 | 1.12147412 |
| 35 | CDC7 | 1.10042859 |
| 36 | PIK3CA | 1.02421245 |
| 37 | CHEK1 | 0.98477990 |
| 38 | NEK2 | 0.98218398 |
| 39 | BCR | 0.96463881 |
| 40 | BRSK1 | 0.96312601 |
| 41 | ATM | 0.94443138 |
| 42 | FGFR1 | 0.93684701 |
| 43 | CASK | 0.88223893 |
| 44 | SRPK1 | 0.86830840 |
| 45 | RPS6KB1 | 0.85206107 |
| 46 | IRAK4 | 0.80766519 |
| 47 | AURKB | 0.80246116 |
| 48 | EIF2AK2 | 0.78061225 |
| 49 | OXSR1 | 0.74958353 |
| 50 | TGFBR1 | 0.73696417 |
| 51 | BMPR1B | 0.73412803 |
| 52 | IRAK2 | 0.72785260 |
| 53 | CDK12 | 0.72276428 |
| 54 | BMX | 0.71853291 |
| 55 | MARK1 | 0.68150776 |
| 56 | NEK6 | 0.67800611 |
| 57 | MST4 | 0.65303627 |
| 58 | MAP3K4 | 0.65244420 |
| 59 | MAP3K2 | 0.64752850 |
| 60 | MAP3K7 | 0.62775692 |
| 61 | YES1 | 0.62166300 |
| 62 | SIK2 | 0.61853888 |
| 63 | STK3 | 0.61567579 |
| 64 | CDK2 | 0.60630094 |
| 65 | CSNK1E | 0.59083145 |
| 66 | CDK1 | 0.58705318 |
| 67 | WNK1 | 0.57599667 |
| 68 | VRK1 | 0.56619395 |
| 69 | MELK | 0.55051596 |
| 70 | FGFR3 | 0.53027209 |
| 71 | IRAK1 | 0.51612921 |
| 72 | PRKDC | 0.51571178 |
| 73 | CAMK1D | 0.50979634 |
| 74 | SIK3 | 0.49930088 |
| 75 | CSNK1G1 | 0.47955515 |
| 76 | MTOR | 0.46310677 |
| 77 | CSNK2A2 | 0.41823893 |
| 78 | ERBB4 | 0.40561898 |
| 79 | CHEK2 | 0.39246561 |
| 80 | LATS1 | 0.39227071 |
| 81 | TNK2 | 0.37611828 |
| 82 | TEC | 0.32766913 |
| 83 | STK11 | 0.32028578 |
| 84 | DYRK1A | 0.31811147 |
| 85 | TAF1 | 0.30660088 |
| 86 | MAPK14 | 0.30358892 |
| 87 | PRKCG | 0.30295325 |
| 88 | FER | 0.30055778 |
| 89 | CLK1 | 0.29855113 |
| 90 | PRKAA1 | 0.29681002 |
| 91 | SGK1 | 0.28796923 |
| 92 | AKT1 | 0.28629940 |
| 93 | IGF1R | 0.28585535 |
| 94 | RPS6KB2 | 0.27403717 |
| 95 | DAPK1 | 0.27223487 |
| 96 | NTRK2 | 0.25673478 |
| 97 | ADRBK2 | 0.25658640 |
| 98 | SGK2 | 0.25619245 |
| 99 | CSNK2A1 | 0.24987307 |
| 100 | PAK3 | 0.24187196 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 4.66518028 |
| 2 | DNA replication_Homo sapiens_hsa03030 | 3.19803266 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 3.17031171 |
| 4 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 3.02258006 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.92895945 |
| 6 | Base excision repair_Homo sapiens_hsa03410 | 2.62039343 |
| 7 | RNA degradation_Homo sapiens_hsa03018 | 2.60677352 |
| 8 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.55188540 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.53794890 |
| 10 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.45136801 |
| 11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.38153438 |
| 12 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 2.37053782 |
| 13 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 2.25343519 |
| 14 | Taste transduction_Homo sapiens_hsa04742 | 2.24797830 |
| 15 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.22726502 |
| 16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.18786770 |
| 17 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 2.12685145 |
| 18 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.11291896 |
| 19 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.10636701 |
| 20 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.08677196 |
| 21 | RNA transport_Homo sapiens_hsa03013 | 2.06216765 |
| 22 | Carbon metabolism_Homo sapiens_hsa01200 | 1.88894014 |
| 23 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.84442999 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.83021228 |
| 25 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.74956408 |
| 26 | Homologous recombination_Homo sapiens_hsa03440 | 1.72813883 |
| 27 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.70045780 |
| 28 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.65057321 |
| 29 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.63125127 |
| 30 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.39306700 |
| 31 | Spliceosome_Homo sapiens_hsa03040 | 1.37262822 |
| 32 | Cell cycle_Homo sapiens_hsa04110 | 1.32678454 |
| 33 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.29697711 |
| 34 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.25375436 |
| 35 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.22004523 |
| 36 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.17995801 |
| 37 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.16009637 |
| 38 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.12452147 |
| 39 | Lysine degradation_Homo sapiens_hsa00310 | 1.03914115 |
| 40 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.03302489 |
| 41 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.01404002 |
| 42 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.98532096 |
| 43 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.94180019 |
| 44 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.93568256 |
| 45 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.89455032 |
| 46 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.87676282 |
| 47 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.84334054 |
| 48 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.82896370 |
| 49 | RNA polymerase_Homo sapiens_hsa03020 | 0.79962766 |
| 50 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.76681979 |
| 51 | Galactose metabolism_Homo sapiens_hsa00052 | 0.76166287 |
| 52 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.75194071 |
| 53 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.70301080 |
| 54 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.70202684 |
| 55 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.69516734 |
| 56 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.68464093 |
| 57 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.67942721 |
| 58 | Proteasome_Homo sapiens_hsa03050 | 0.67739741 |
| 59 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.66715286 |
| 60 | Purine metabolism_Homo sapiens_hsa00230 | 0.64583223 |
| 61 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.63191141 |
| 62 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.61492917 |
| 63 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.58760629 |
| 64 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.54468857 |
| 65 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.54341922 |
| 66 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.52579394 |
| 67 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.46105722 |
| 68 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.45352393 |
| 69 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.44947218 |
| 70 | Legionellosis_Homo sapiens_hsa05134 | 0.44893537 |
| 71 | Adherens junction_Homo sapiens_hsa04520 | 0.43773958 |
| 72 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.40814789 |
| 73 | Olfactory transduction_Homo sapiens_hsa04740 | 0.40232896 |
| 74 | Thyroid cancer_Homo sapiens_hsa05216 | 0.39823286 |
| 75 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.39384005 |
| 76 | Peroxisome_Homo sapiens_hsa04146 | 0.38170024 |
| 77 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.36803511 |
| 78 | Nicotine addiction_Homo sapiens_hsa05033 | 0.31472409 |
| 79 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.30528723 |
| 80 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.28066248 |
| 81 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.27575967 |
| 82 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.25168685 |
| 83 | Metabolic pathways_Homo sapiens_hsa01100 | 0.24099304 |
| 84 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.23553991 |
| 85 | ABC transporters_Homo sapiens_hsa02010 | 0.21508655 |
| 86 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.20825164 |
| 87 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.19682544 |
| 88 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.18070094 |
| 89 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.17517614 |
| 90 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.14879683 |
| 91 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.14657026 |
| 92 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.13679213 |
| 93 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.12690999 |
| 94 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.12327734 |
| 95 | GABAergic synapse_Homo sapiens_hsa04727 | 0.09585535 |
| 96 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.09323084 |
| 97 | Mineral absorption_Homo sapiens_hsa04978 | 0.08639898 |
| 98 | Histidine metabolism_Homo sapiens_hsa00340 | 0.06952250 |
| 99 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.06401049 |
| 100 | Morphine addiction_Homo sapiens_hsa05032 | 0.05700361 |

