TATDN1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.73380913
2ATP synthesis coupled proton transport (GO:0015986)6.61825656
3energy coupled proton transport, down electrochemical gradient (GO:0015985)6.61825656
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.59664726
5mitochondrial respiratory chain complex I assembly (GO:0032981)5.11962852
6NADH dehydrogenase complex assembly (GO:0010257)5.11962852
7mitochondrial respiratory chain complex I biogenesis (GO:0097031)5.11962852
8cullin deneddylation (GO:0010388)4.93527195
9transcription elongation from RNA polymerase III promoter (GO:0006385)4.92303752
10termination of RNA polymerase III transcription (GO:0006386)4.92303752
11protein complex biogenesis (GO:0070271)4.83813724
12proteasome assembly (GO:0043248)4.73087081
13respiratory electron transport chain (GO:0022904)4.71554909
14electron transport chain (GO:0022900)4.58939979
15mitochondrial respiratory chain complex assembly (GO:0033108)4.53487459
16peptidyl-histidine modification (GO:0018202)4.52940521
17protein deneddylation (GO:0000338)4.45248249
18chaperone-mediated protein transport (GO:0072321)4.26913451
19GTP biosynthetic process (GO:0006183)4.25569367
20regulation of mitochondrial translation (GO:0070129)4.16693923
21chromatin remodeling at centromere (GO:0031055)4.11358457
22CENP-A containing nucleosome assembly (GO:0034080)4.10276834
237-methylguanosine mRNA capping (GO:0006370)4.04326242
24protein neddylation (GO:0045116)4.04191287
25negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.01157705
267-methylguanosine RNA capping (GO:0009452)3.95459743
27RNA capping (GO:0036260)3.95459743
28signal peptide processing (GO:0006465)3.89593611
29ribosomal small subunit biogenesis (GO:0042274)3.85957773
30positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.82739343
31respiratory chain complex IV assembly (GO:0008535)3.77723843
32nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.77151641
33exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.73721607
34regulation of cellular amino acid metabolic process (GO:0006521)3.71721936
35RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.68642620
36tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.68642620
37protein targeting to mitochondrion (GO:0006626)3.68327025
38cotranslational protein targeting to membrane (GO:0006613)3.68158890
39transcription elongation from RNA polymerase I promoter (GO:0006362)3.67094632
40protein-cofactor linkage (GO:0018065)3.67043001
41DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.65404358
42signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.63970521
43intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.63970521
44signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.63904568
45signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.63904568
46signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.63904568
47SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.63131929
48guanosine-containing compound biosynthetic process (GO:1901070)3.62547540
49regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.62415516
50L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.60890555
51protein targeting to ER (GO:0045047)3.58355158
52establishment of protein localization to endoplasmic reticulum (GO:0072599)3.55798013
53antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.55585033
54cytochrome complex assembly (GO:0017004)3.55183528
55UTP biosynthetic process (GO:0006228)3.54977079
56negative regulation of ligase activity (GO:0051352)3.54194940
57negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.54194940
58translation (GO:0006412)3.53691840
59establishment of integrated proviral latency (GO:0075713)3.52903105
60histone exchange (GO:0043486)3.50968523
61regulation of mitotic spindle checkpoint (GO:1903504)3.49201922
62regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.49201922
63protein localization to endoplasmic reticulum (GO:0070972)3.48902043
64establishment of protein localization to mitochondrion (GO:0072655)3.46637984
65inner mitochondrial membrane organization (GO:0007007)3.43961341
66purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.42767537
67signal transduction involved in DNA damage checkpoint (GO:0072422)3.41775738
68signal transduction involved in DNA integrity checkpoint (GO:0072401)3.41775738
69antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.40710031
70purine nucleoside triphosphate biosynthetic process (GO:0009145)3.39645427
71termination of RNA polymerase I transcription (GO:0006363)3.38732330
72viral transcription (GO:0019083)3.38476193
73translational termination (GO:0006415)3.38415962
74signal transduction involved in cell cycle checkpoint (GO:0072395)3.38067207
75anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.37249857
76translational initiation (GO:0006413)3.37039540
77DNA replication checkpoint (GO:0000076)3.35501176
78DNA double-strand break processing (GO:0000729)3.31718174
79maturation of SSU-rRNA (GO:0030490)3.30806608
80establishment of protein localization to mitochondrial membrane (GO:0090151)3.29369037
81positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.28954395
82establishment of viral latency (GO:0019043)3.28561707
83transcription-coupled nucleotide-excision repair (GO:0006283)3.27727993
84pseudouridine synthesis (GO:0001522)3.27532134
85maturation of 5.8S rRNA (GO:0000460)3.25117605
86protein localization to mitochondrion (GO:0070585)3.23658543
87water-soluble vitamin biosynthetic process (GO:0042364)3.23344251
88amino acid salvage (GO:0043102)3.21410272
89L-methionine salvage (GO:0071267)3.21410272
90L-methionine biosynthetic process (GO:0071265)3.21410272
91oxidative phosphorylation (GO:0006119)3.20651708
92cellular component biogenesis (GO:0044085)3.19816097
93ATP biosynthetic process (GO:0006754)3.19109871
94transcription from RNA polymerase I promoter (GO:0006360)3.18177943
95spliceosomal snRNP assembly (GO:0000387)3.17896090
96UTP metabolic process (GO:0046051)3.16935265
97rRNA methylation (GO:0031167)3.16562952
98positive regulation of ligase activity (GO:0051351)3.15766490
99dopamine transport (GO:0015872)3.13248895
100histone mRNA metabolic process (GO:0008334)3.11650540
101cellular protein complex disassembly (GO:0043624)3.07460145
102mannosylation (GO:0097502)3.06985126
103nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.06625063
104DNA damage response, detection of DNA damage (GO:0042769)3.05690253
105negative regulation of DNA-dependent DNA replication (GO:2000104)3.05354740
106purine nucleobase biosynthetic process (GO:0009113)3.05100312
107DNA replication-independent nucleosome organization (GO:0034724)3.03823471
108DNA replication-independent nucleosome assembly (GO:0006336)3.03823471
109ribosomal small subunit assembly (GO:0000028)3.03731760
110replication fork processing (GO:0031297)3.03590367
111CTP biosynthetic process (GO:0006241)3.03195762
112CTP metabolic process (GO:0046036)3.03195762
113viral life cycle (GO:0019058)3.01471831
114ribonucleoside triphosphate biosynthetic process (GO:0009201)3.01252807
115transcription initiation from RNA polymerase I promoter (GO:0006361)3.01058915
116ribosomal large subunit biogenesis (GO:0042273)2.98244983
117rRNA modification (GO:0000154)2.96695196
118de novo posttranslational protein folding (GO:0051084)2.96154609
119regulation of cellular amine metabolic process (GO:0033238)2.95792849
120ribonucleoprotein complex biogenesis (GO:0022613)2.93317033
121organelle disassembly (GO:1903008)2.91720869
122translational elongation (GO:0006414)2.91541001
123rRNA processing (GO:0006364)2.90829194
124de novo protein folding (GO:0006458)2.90156401
125positive regulation of mitochondrial fission (GO:0090141)2.87420299
126intracellular protein transmembrane import (GO:0044743)2.87178937
127protein K6-linked ubiquitination (GO:0085020)2.85714092
128antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.85221398
129hydrogen ion transmembrane transport (GO:1902600)2.84061923
130rRNA metabolic process (GO:0016072)2.83047652
131DNA catabolic process, exonucleolytic (GO:0000738)2.76624389
132mitotic metaphase plate congression (GO:0007080)2.76232243
133spliceosomal complex assembly (GO:0000245)2.72361889

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human5.39497268
2* GABP_17652178_ChIP-ChIP_JURKAT_Human4.54411035
3EST1_17652178_ChIP-ChIP_JURKAT_Human4.33255206
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.80668908
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.64547850
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.61541891
7CREB1_15753290_ChIP-ChIP_HEK293T_Human3.40327604
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.31842990
9MYC_18555785_ChIP-Seq_MESCs_Mouse3.26034465
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.22304846
11PDX1_19855005_ChIP-ChIP_MIN6_Mouse3.17270144
12ELF1_17652178_ChIP-ChIP_JURKAT_Human3.16110971
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.12048731
14CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.09132922
15CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.04442853
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.90639120
17ELK1_19687146_ChIP-ChIP_HELA_Human2.75677927
18VDR_23849224_ChIP-Seq_CD4+_Human2.68831997
19* SRF_21415370_ChIP-Seq_HL-1_Mouse2.60381634
20EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.44076796
21RBPJ_22232070_ChIP-Seq_NCS_Mouse2.43488566
22DCP1A_22483619_ChIP-Seq_HELA_Human2.34383541
23MYC_18358816_ChIP-ChIP_MESCs_Mouse2.31333358
24MYC_19030024_ChIP-ChIP_MESCs_Mouse2.23428453
25FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.17412172
26FOXP3_21729870_ChIP-Seq_TREG_Human2.12178167
27HOXB4_20404135_ChIP-ChIP_EML_Mouse2.02282610
28THAP11_20581084_ChIP-Seq_MESCs_Mouse1.99122052
29* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.94809235
30* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.92652854
31PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.91092520
32HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.86767193
33PADI4_21655091_ChIP-ChIP_MCF-7_Human1.86217662
34XRN2_22483619_ChIP-Seq_HELA_Human1.81743713
35YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.77461457
36MYC_19079543_ChIP-ChIP_MESCs_Mouse1.76127416
37TTF2_22483619_ChIP-Seq_HELA_Human1.72890683
38ELK1_22589737_ChIP-Seq_MCF10A_Human1.69594571
39FUS_26573619_Chip-Seq_HEK293_Human1.66585637
40* GABP_19822575_ChIP-Seq_HepG2_Human1.65709731
41MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.62617837
42ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.58231849
43* FOXM1_23109430_ChIP-Seq_U2OS_Human1.53725509
44POU3F2_20337985_ChIP-ChIP_501MEL_Human1.49819820
45IGF1R_20145208_ChIP-Seq_DFB_Human1.49267875
46TAF15_26573619_Chip-Seq_HEK293_Human1.48609687
47YY1_21170310_ChIP-Seq_MESCs_Mouse1.46658721
48VDR_22108803_ChIP-Seq_LS180_Human1.44501219
49NOTCH1_21737748_ChIP-Seq_TLL_Human1.44124006
50POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.43211737
51IRF1_19129219_ChIP-ChIP_H3396_Human1.42626750
52KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.31815299
53ERG_20887958_ChIP-Seq_HPC-7_Mouse1.31372926
54ZFP57_27257070_Chip-Seq_ESCs_Mouse1.28651788
55EWS_26573619_Chip-Seq_HEK293_Human1.28262203
56CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.27928630
57E2F4_17652178_ChIP-ChIP_JURKAT_Human1.27726378
58FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.27237342
59FLI1_27457419_Chip-Seq_LIVER_Mouse1.27119074
60CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.26920338
61SOX2_16153702_ChIP-ChIP_HESCs_Human1.23999779
62MYCN_18555785_ChIP-Seq_MESCs_Mouse1.23030900
63SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.22481985
64E2F1_21310950_ChIP-Seq_MCF-7_Human1.21466420
65CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.20220833
66CTBP1_25329375_ChIP-Seq_LNCAP_Human1.19061020
67NANOG_16153702_ChIP-ChIP_HESCs_Human1.18974210
68MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.17880145
69CTBP2_25329375_ChIP-Seq_LNCAP_Human1.15814027
70ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.15651960
71FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.15028944
72FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.15017641
73EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12907344
74TP53_22573176_ChIP-Seq_HFKS_Human1.12569871
75FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.11949425
76SOX17_20123909_ChIP-Seq_XEN_Mouse1.11084481
77GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08196680
78AR_21909140_ChIP-Seq_LNCAP_Human1.06696301
79PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.05890125
80PCGF2_27294783_Chip-Seq_ESCs_Mouse1.05810567
81MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.02786753
82BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.02529096
83CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.98422165
84* GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.98219032
85NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.98194332
86GBX2_23144817_ChIP-Seq_PC3_Human0.97491373
87TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.96649717
88POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.95823510
89HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.94543132
90SALL1_21062744_ChIP-ChIP_HESCs_Human0.93808821
91POU5F1_16153702_ChIP-ChIP_HESCs_Human0.93163394
92FOXA1_27270436_Chip-Seq_PROSTATE_Human0.93124128
93FOXA1_25329375_ChIP-Seq_VCAP_Human0.93124128
94ZNF274_21170338_ChIP-Seq_K562_Hela0.92245912
95TP63_19390658_ChIP-ChIP_HaCaT_Human0.92235822
96DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.90246605
97SOX2_18555785_ChIP-Seq_MESCs_Mouse0.89080592
98RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.89077172
99* ER_23166858_ChIP-Seq_MCF-7_Human0.88611519
100NANOG_19829295_ChIP-Seq_ESCs_Human0.88060614
101SOX2_19829295_ChIP-Seq_ESCs_Human0.88060614
102ZFX_18555785_ChIP-Seq_MESCs_Mouse0.87921476
103CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.87572000
104NFE2_27457419_Chip-Seq_LIVER_Mouse0.87042172
105SUZ12_27294783_Chip-Seq_NPCs_Mouse0.86508508
106MYC_18940864_ChIP-ChIP_HL60_Human0.86374932
107EZH2_27294783_Chip-Seq_NPCs_Mouse0.85197802
108PCGF2_27294783_Chip-Seq_NPCs_Mouse0.84513338
109TFEB_21752829_ChIP-Seq_HELA_Human0.84085888
110E2F7_22180533_ChIP-Seq_HELA_Human0.82810198
111REST_19997604_ChIP-ChIP_NEURONS_Mouse0.82675718
112CBP_20019798_ChIP-Seq_JUKART_Human0.81062326
113IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.81062326
114NANOG_18555785_ChIP-Seq_MESCs_Mouse0.80489824
115SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.78975072
116P300_19829295_ChIP-Seq_ESCs_Human0.78394632
117TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77076162
118CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.76029005
119MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.74985302
120SALL4_22934838_ChIP-ChIP_CD34+_Human0.74496491
121GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.74481026
122CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.73904433
123SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.73686263
124CIITA_25753668_ChIP-Seq_RAJI_Human0.73644895
125SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.73446408
126BMI1_23680149_ChIP-Seq_NPCS_Mouse0.73375888

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009697_abnormal_copulation5.08708990
2MP0001529_abnormal_vocalization3.65237234
3MP0008057_abnormal_DNA_replication3.46905240
4MP0003136_yellow_coat_color3.02788868
5MP0000372_irregular_coat_pigmentation2.83567529
6MP0009379_abnormal_foot_pigmentation2.73291976
7MP0002638_abnormal_pupillary_reflex2.73018575
8MP0001905_abnormal_dopamine_level2.64056638
9MP0003806_abnormal_nucleotide_metabolis2.62921964
10MP0001188_hyperpigmentation2.58987193
11MP0003656_abnormal_erythrocyte_physiolo2.27218503
12MP0006292_abnormal_olfactory_placode2.23462123
13MP0008058_abnormal_DNA_repair2.23142202
14MP0001764_abnormal_homeostasis2.22625343
15MP0004957_abnormal_blastocyst_morpholog2.22342904
16MP0006276_abnormal_autonomic_nervous2.20979445
17MP0006036_abnormal_mitochondrial_physio2.16976529
18MP0002102_abnormal_ear_morphology2.15479965
19MP0004145_abnormal_muscle_electrophysio2.14050859
20MP0010386_abnormal_urinary_bladder2.05539653
21MP0005409_darkened_coat_color2.03550355
22MP0003941_abnormal_skin_development1.94517261
23MP0003186_abnormal_redox_activity1.94245119
24MP0006035_abnormal_mitochondrial_morpho1.94099571
25MP0001293_anophthalmia1.90197818
26MP0002138_abnormal_hepatobiliary_system1.77012156
27MP0008932_abnormal_embryonic_tissue1.74847787
28MP0003693_abnormal_embryo_hatching1.72897982
29MP0006072_abnormal_retinal_apoptosis1.72026971
30MP0000749_muscle_degeneration1.70812596
31MP0000015_abnormal_ear_pigmentation1.67257157
32MP0008995_early_reproductive_senescence1.64195417
33MP0003718_maternal_effect1.60791546
34MP0003011_delayed_dark_adaptation1.56018004
35MP0004147_increased_porphyrin_level1.51095052
36MP0001984_abnormal_olfaction1.50568199
37MP0003122_maternal_imprinting1.44288324
38MP0001986_abnormal_taste_sensitivity1.42590279
39MP0005551_abnormal_eye_electrophysiolog1.40723674
40MP0003880_abnormal_central_pattern1.39271868
41MP0001485_abnormal_pinna_reflex1.38698104
42MP0005171_absent_coat_pigmentation1.36664705
43MP0002234_abnormal_pharynx_morphology1.30982026
44MP0002751_abnormal_autonomic_nervous1.30290544
45MP0010030_abnormal_orbit_morphology1.29058333
46MP0008789_abnormal_olfactory_epithelium1.28860657
47MP0002163_abnormal_gland_morphology1.28316440
48MP0003567_abnormal_fetal_cardiomyocyte1.27698950
49MP0002277_abnormal_respiratory_mucosa1.24363759
50MP0000631_abnormal_neuroendocrine_gland1.22805671
51MP0000569_abnormal_digit_pigmentation1.22151132
52MP0002938_white_spotting1.21794485
53MP0002210_abnormal_sex_determination1.21190844
54MP0003937_abnormal_limbs/digits/tail_de1.19855647
55MP0004142_abnormal_muscle_tone1.18376641
56MP0003787_abnormal_imprinting1.13924484
57MP0002184_abnormal_innervation1.13829576
58MP0001286_abnormal_eye_development1.13553451
59MP0004133_heterotaxia1.12929459
60MP0005084_abnormal_gallbladder_morpholo1.12192313
61MP0005423_abnormal_somatic_nervous1.11236931
62MP0005376_homeostasis/metabolism_phenot1.10624448
63MP0010094_abnormal_chromosome_stability1.10598380
64MP0005646_abnormal_pituitary_gland1.10000024
65MP0002837_dystrophic_cardiac_calcinosis1.09994455
66MP0008872_abnormal_physiological_respon1.09181235
67MP0001929_abnormal_gametogenesis1.08991797
68MP0003195_calcinosis1.08958001
69MP0002139_abnormal_hepatobiliary_system1.08534203
70MP0003119_abnormal_digestive_system1.04643359
71MP0002233_abnormal_nose_morphology1.03730977
72MP0008877_abnormal_DNA_methylation1.03176094
73MP0008875_abnormal_xenobiotic_pharmacok1.02492521
74MP0003786_premature_aging1.01782425
75MP0001145_abnormal_male_reproductive1.01731560
76MP0000653_abnormal_sex_gland1.00367434
77MP0008004_abnormal_stomach_pH0.99494128
78MP0001968_abnormal_touch/_nociception0.99266932
79MP0001542_abnormal_bone_strength0.97961343
80MP0005408_hypopigmentation0.96473451
81MP0002148_abnormal_hypersensitivity_rea0.95754102
82MP0005174_abnormal_tail_pigmentation0.95049447
83MP0002160_abnormal_reproductive_system0.92381537
84MP0002876_abnormal_thyroid_physiology0.91212700
85MP0003077_abnormal_cell_cycle0.91207917
86MP0005379_endocrine/exocrine_gland_phen0.91050333
87MP0004036_abnormal_muscle_relaxation0.90195894
88MP0005266_abnormal_metabolism0.90064044
89MP0004883_abnormal_blood_vessel0.89514275
90MP0000647_abnormal_sebaceous_gland0.88922975
91MP0005391_vision/eye_phenotype0.88298825
92MP0004742_abnormal_vestibular_system0.87980005
93MP0008260_abnormal_autophagy0.87957896
94MP0005058_abnormal_lysosome_morphology0.87303280
95MP0002697_abnormal_eye_size0.85931733
96MP0009046_muscle_twitch0.85401412
97MP0000566_synostosis0.85107637
98MP0004270_analgesia0.84353631
99MP0002272_abnormal_nervous_system0.82768879
100MP0003698_abnormal_male_reproductive0.82350810
101MP0000358_abnormal_cell_content/0.81766741
102MP0005389_reproductive_system_phenotype0.80896749
103MP0000049_abnormal_middle_ear0.80831489
104MP0003121_genomic_imprinting0.79980740
105MP0003111_abnormal_nucleus_morphology0.79951155
106MP0003137_abnormal_impulse_conducting0.79853478
107MP0005253_abnormal_eye_physiology0.79749029
108MP0003938_abnormal_ear_development0.79739816
109MP0005332_abnormal_amino_acid0.79675423
110MP0005195_abnormal_posterior_eye0.79582496
111MP0002736_abnormal_nociception_after0.78925267
112MP0000427_abnormal_hair_cycle0.78826994
113MP0001697_abnormal_embryo_size0.78639788
114MP0005394_taste/olfaction_phenotype0.77909778
115MP0005499_abnormal_olfactory_system0.77909778
116MP0000230_abnormal_systemic_arterial0.75828219
117MP0005075_abnormal_melanosome_morpholog0.75525484
118MP0001324_abnormal_eye_pigmentation0.74033946
119MP0003890_abnormal_embryonic-extraembry0.73646113
120MP0000516_abnormal_urinary_system0.72580554
121MP0005367_renal/urinary_system_phenotyp0.72580554
122MP0002090_abnormal_vision0.72354474
123MP0000920_abnormal_myelination0.70756727
124MP0002085_abnormal_embryonic_tissue0.70043919
125MP0002084_abnormal_developmental_patter0.69588695
126MP0008007_abnormal_cellular_replicative0.69089559
127MP0002752_abnormal_somatic_nervous0.69024401
128MP0001440_abnormal_grooming_behavior0.68890999
129MP0001664_abnormal_digestion0.68862018
130MP0005085_abnormal_gallbladder_physiolo0.68087724
131MP0003315_abnormal_perineum_morphology0.66969997
132MP0001501_abnormal_sleep_pattern0.66430307
133MP0004215_abnormal_myocardial_fiber0.65387450
134MP0004084_abnormal_cardiac_muscle0.65292393
135MP0002557_abnormal_social/conspecific_i0.64146308
136MP0000538_abnormal_urinary_bladder0.62865515
137MP0002734_abnormal_mechanical_nocicepti0.62655958
138MP0002177_abnormal_outer_ear0.62514387
139MP0005535_abnormal_body_temperature0.61866336
140MP0000778_abnormal_nervous_system0.60371803
141MP0006082_CNS_inflammation0.59640065
142MP0002095_abnormal_skin_pigmentation0.59522285
143MP0003950_abnormal_plasma_membrane0.58987471
144MP0009333_abnormal_splenocyte_physiolog0.58147551
145MP0002106_abnormal_muscle_physiology0.56897948
146MP0005645_abnormal_hypothalamus_physiol0.56289875
147MP0005164_abnormal_response_to0.55836030

Predicted human phenotypes

RankGene SetZ-score
1Renal Fanconi syndrome (HP:0001994)6.01592671
2Acute necrotizing encephalopathy (HP:0006965)5.71381682
3Mitochondrial inheritance (HP:0001427)5.22929408
4Abnormal mitochondria in muscle tissue (HP:0008316)4.98234748
5Hepatocellular necrosis (HP:0001404)4.66096582
6Acute encephalopathy (HP:0006846)4.65526687
7Progressive macrocephaly (HP:0004481)4.65042247
8Increased CSF lactate (HP:0002490)4.45500960
9Increased hepatocellular lipid droplets (HP:0006565)4.44317423
10Hepatic necrosis (HP:0002605)4.00342350
11Abnormality of renal resorption (HP:0011038)3.84836057
12Lipid accumulation in hepatocytes (HP:0006561)3.82206478
13Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.57832169
14Hypothermia (HP:0002045)3.39741432
15Osteomalacia (HP:0002749)3.31850108
16Parakeratosis (HP:0001036)3.31808526
17Birth length less than 3rd percentile (HP:0003561)3.30546766
18Cerebral edema (HP:0002181)3.28665552
19Congenital, generalized hypertrichosis (HP:0004540)3.14043767
20Colon cancer (HP:0003003)2.96695890
21Hyperphosphaturia (HP:0003109)2.96589458
22Abnormality of glycolysis (HP:0004366)2.93096855
23Increased serum pyruvate (HP:0003542)2.93096855
24Exercise intolerance (HP:0003546)2.91700416
25Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.87284787
263-Methylglutaconic aciduria (HP:0003535)2.87167868
27Respiratory failure (HP:0002878)2.84382277
28Neuroendocrine neoplasm (HP:0100634)2.83364262
29Abnormality of cells of the erythroid lineage (HP:0012130)2.81557784
30Increased serum lactate (HP:0002151)2.75809290
31Lactic acidosis (HP:0003128)2.74443021
32Leukodystrophy (HP:0002415)2.73052428
33Aplastic anemia (HP:0001915)2.72418991
34True hermaphroditism (HP:0010459)2.72203348
35Optic disc pallor (HP:0000543)2.71662971
36Meckel diverticulum (HP:0002245)2.70332054
37Exertional dyspnea (HP:0002875)2.69016942
38Abnormality of the labia minora (HP:0012880)2.67847598
39Pheochromocytoma (HP:0002666)2.63034124
40Microvesicular hepatic steatosis (HP:0001414)2.62662191
41Abnormality of the ileum (HP:0001549)2.60771330
42Aplasia/Hypoplasia of the uvula (HP:0010293)2.60408100
43Abnormal number of erythroid precursors (HP:0012131)2.59140272
44Chromosomal breakage induced by crosslinking agents (HP:0003221)2.58137672
45Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.56892028
46Abnormality of the heme biosynthetic pathway (HP:0010472)2.56831236
47Increased intramyocellular lipid droplets (HP:0012240)2.54806466
48Septo-optic dysplasia (HP:0100842)2.54178639
49Decreased activity of mitochondrial respiratory chain (HP:0008972)2.52621756
50Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.52621756
51Respiratory difficulties (HP:0002880)2.50506831
52Chromsome breakage (HP:0040012)2.49655258
53Nephronophthisis (HP:0000090)2.48578078
54Hypoplastic pelvis (HP:0008839)2.44718613
55Abnormality of dentin (HP:0010299)2.42443010
56Abnormality of the pons (HP:0007361)2.38710522
57Abnormal hair whorl (HP:0010721)2.34280199
58Abnormality of chromosome stability (HP:0003220)2.32812320
59Hypoplasia of the pons (HP:0012110)2.32412783
60Fibular aplasia (HP:0002990)2.28596550
61Abnormal urine phosphate concentration (HP:0012599)2.25502873
62Medial flaring of the eyebrow (HP:0010747)2.25482779
63Abnormality of methionine metabolism (HP:0010901)2.24312830
64Abnormality of aspartate family amino acid metabolism (HP:0010899)2.22190341
65Abnormality of the preputium (HP:0100587)2.21635213
66Absent thumb (HP:0009777)2.21172510
67X-linked dominant inheritance (HP:0001423)2.19879384
68Hyperglycinemia (HP:0002154)2.19750441
69Abnormality of serum amino acid levels (HP:0003112)2.17990692
70Autoamputation (HP:0001218)2.17655537
71Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.15941338
72Abnormality of alanine metabolism (HP:0010916)2.15723375
73Hyperalaninemia (HP:0003348)2.15723375
74Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.15723375
75Triphalangeal thumb (HP:0001199)2.15387329
76Aplasia/Hypoplasia of the fovea (HP:0008060)2.14243429
77Hypoplasia of the fovea (HP:0007750)2.14243429
78Proximal tubulopathy (HP:0000114)2.13534870
79Aplasia/hypoplasia of the uterus (HP:0008684)2.12657183
80Degeneration of anterior horn cells (HP:0002398)2.12363158
81Abnormality of the anterior horn cell (HP:0006802)2.12363158
82Renal tubular dysfunction (HP:0000124)2.05991969
83CNS demyelination (HP:0007305)2.05694277
84Macrocytic anemia (HP:0001972)2.03932206
85Cerebral hypomyelination (HP:0006808)2.02835884
86Congenital primary aphakia (HP:0007707)2.02760838
87Glycosuria (HP:0003076)1.99455037
88Abnormality of urine glucose concentration (HP:0011016)1.99455037
89Abnormality of the renal medulla (HP:0100957)1.99439951
90Nephrogenic diabetes insipidus (HP:0009806)1.99185633
91Gait imbalance (HP:0002141)1.99078423
92Hypoplastic left heart (HP:0004383)1.98248844
93Stenosis of the external auditory canal (HP:0000402)1.97911090
94Pallor (HP:0000980)1.97269764
95Sclerocornea (HP:0000647)1.95285221
96Pancreatic cysts (HP:0001737)1.95103870
97Abnormality of placental membranes (HP:0011409)1.95054437
98Amniotic constriction ring (HP:0009775)1.95054437
99Methylmalonic acidemia (HP:0002912)1.94002472
100Aplasia/Hypoplasia of the lens (HP:0008063)1.91264510
101Small intestinal stenosis (HP:0012848)1.91087117
102Duodenal stenosis (HP:0100867)1.91087117
103Absent septum pellucidum (HP:0001331)1.91007655
104Pendular nystagmus (HP:0012043)1.90926066
105Intestinal atresia (HP:0011100)1.90115043
106Abnormal protein glycosylation (HP:0012346)1.89670406
107Abnormal glycosylation (HP:0012345)1.89670406
108Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.89670406
109Abnormal protein N-linked glycosylation (HP:0012347)1.89670406
110Increased muscle lipid content (HP:0009058)1.89570142
111Split foot (HP:0001839)1.89230504
112Lethargy (HP:0001254)1.88976511
113Hyperglycinuria (HP:0003108)1.87821790
114Methylmalonic aciduria (HP:0012120)1.87410067
115Abnormal lung lobation (HP:0002101)1.87277319
116Oral leukoplakia (HP:0002745)1.86170406
117Irregular epiphyses (HP:0010582)1.85936705
118Reticulocytopenia (HP:0001896)1.83571827
119Aplasia/Hypoplasia of the tongue (HP:0010295)1.82301672
120Abnormality of the duodenum (HP:0002246)1.81640255
121Volvulus (HP:0002580)1.80420037
122Reduced antithrombin III activity (HP:0001976)1.80251066
123Sloping forehead (HP:0000340)1.78014200
124Optic nerve hypoplasia (HP:0000609)1.76374011
125Carpal bone hypoplasia (HP:0001498)1.76115465
126Abnormality of aromatic amino acid family metabolism (HP:0004338)1.75206438
127Postnatal microcephaly (HP:0005484)1.75002150
128Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.74267210
129Broad face (HP:0000283)1.73705970
130Opisthotonus (HP:0002179)1.73589435
131Duplicated collecting system (HP:0000081)1.71644293
132Abnormality of the renal cortex (HP:0011035)1.70506871
133Septate vagina (HP:0001153)1.69927663
134Congenital ichthyosiform erythroderma (HP:0007431)1.69584481
135Abnormal pupillary function (HP:0007686)1.69354708
136Long clavicles (HP:0000890)1.69271408
137Abnormality of the septum pellucidum (HP:0007375)1.69172781
138Male pseudohermaphroditism (HP:0000037)1.69047590
139Abnormality of glycine metabolism (HP:0010895)1.68316344
140Emotional lability (HP:0000712)1.68135578
141Rough bone trabeculation (HP:0100670)1.67669434
142Hypoplastic heart (HP:0001961)1.67095731
143Type I transferrin isoform profile (HP:0003642)1.66789848
144Pancreatic fibrosis (HP:0100732)1.60801963
145Congenital sensorineural hearing impairment (HP:0008527)1.58944833
146Aplasia/Hypoplasia of the sacrum (HP:0008517)1.56870060
147Abnormality of midbrain morphology (HP:0002418)1.53970119
148Molar tooth sign on MRI (HP:0002419)1.53970119
149Rectal fistula (HP:0100590)1.47845445
150Rectovaginal fistula (HP:0000143)1.47845445

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.13484772
2NME23.53578807
3VRK23.38226672
4BUB13.11954136
5ACVR1B2.96853259
6EIF2AK32.69659060
7SRPK12.54409387
8NME12.47016286
9ZAK2.44291354
10TRIM282.34599398
11PIK3CG2.28039911
12EIF2AK12.27666244
13PBK2.23771044
14MST42.22832617
15VRK12.22724627
16WNK32.20877763
17NUAK12.20677323
18NEK12.17593044
19BCR2.14068890
20MAP4K22.05052113
21BRSK22.04729841
22GRK71.91275207
23TTK1.83246978
24MAP3K121.75458021
25TAF11.70845658
26WEE11.58899791
27PLK31.53433536
28CASK1.50538544
29ERBB31.45894706
30DYRK21.40198418
31PLK21.40189659
32TRPM71.39094040
33ARAF1.36625187
34PIM21.33711503
35GRK11.31027860
36MKNK11.24428337
37MUSK1.22840151
38BRSK11.18006341
39EIF2AK21.15372779
40PLK41.15271484
41OBSCN1.14796473
42ADRBK21.11969335
43SIK31.06007358
44DYRK31.03116176
45BRAF0.99561636
46GRK50.98828006
47MAPKAPK50.98673157
48WNK40.97840142
49MYLK0.97133300
50NEK20.96468275
51BMPR20.93732667
52MAP2K70.93495076
53CDK190.91471336
54LIMK10.91313835
55TNIK0.91197290
56AKT30.90246476
57BMPR1B0.88462057
58MAPK130.85302756
59TGFBR10.84632300
60STK38L0.84043309
61PINK10.83864034
62MAP3K40.82729109
63ATR0.81504151
64CSNK1G30.80022318
65CHEK20.78384752
66CAMK2B0.74388250
67FGR0.74327905
68OXSR10.74300885
69STK30.70618890
70CSNK2A10.69726563
71MKNK20.68993752
72MAPK150.68059319
73PDK20.68006560
74TSSK60.67943821
75AURKA0.67745924
76CSNK2A20.67719626
77PNCK0.67116142
78PLK10.64680542
79INSRR0.60934165
80CAMK2D0.60786836
81AURKB0.60059325
82RPS6KA50.58953300
83CDK80.58187285
84IRAK40.57403527
85NTRK30.57149874
86CCNB10.56025094
87STK390.55419134
88CDK30.55191433
89FRK0.54294023
90ATM0.53815429
91CSNK1G10.53198513
92PIK3CA0.53065228
93BCKDK0.51889115
94TXK0.51383818
95DYRK1A0.51102351
96PASK0.50059944
97TESK20.49343599
98CSNK1G20.46090500
99CSNK1E0.45148366
100PRPF4B0.44558471
101PAK30.43639835
102PTK2B0.43393764
103CAMK2G0.42905857
104YES10.42164177
105FLT30.42004829
106PRKCG0.41971740
107PRKG20.41835665
108PRKCI0.41734113
109TIE10.39968908
110STK40.39815315
111CDC70.39651540
112FGFR10.39393925
113PRKCE0.38773612
114RPS6KA40.38703512
115ADRBK10.38463332
116TEC0.37303805
117FGFR20.36974287
118NEK60.36569294
119MAP2K20.36523273
120CHEK10.36181150
121MAP3K110.36107291
122TAOK30.35274565
123ERBB40.34569895
124CDK140.33717004
125CDK180.33155568
126TLK10.32620735
127MOS0.30760550
128PRKACA0.29888907
129PHKG10.27959390
130PHKG20.27959390
131CSNK1A10.27697552
132CDK10.27334086
133ALK0.25283306
134RPS6KB20.24763843
135ILK0.24417512

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.66698543
2Oxidative phosphorylation_Homo sapiens_hsa001904.50173383
3Protein export_Homo sapiens_hsa030604.05376687
4Ribosome_Homo sapiens_hsa030104.04984236
5RNA polymerase_Homo sapiens_hsa030203.89111176
6Parkinsons disease_Homo sapiens_hsa050123.77593521
7Alzheimers disease_Homo sapiens_hsa050102.69328665
8Huntingtons disease_Homo sapiens_hsa050162.61960563
9Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.43583925
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.41111853
11Pyrimidine metabolism_Homo sapiens_hsa002402.21018596
12Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.17211187
13Steroid biosynthesis_Homo sapiens_hsa001001.86384553
14Spliceosome_Homo sapiens_hsa030401.85996370
15Nucleotide excision repair_Homo sapiens_hsa034201.83347279
16SNARE interactions in vesicular transport_Homo sapiens_hsa041301.65369161
17Non-homologous end-joining_Homo sapiens_hsa034501.64016133
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.58300387
19Folate biosynthesis_Homo sapiens_hsa007901.55873434
20Homologous recombination_Homo sapiens_hsa034401.52336255
21Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.48684223
22Basal transcription factors_Homo sapiens_hsa030221.45561574
23DNA replication_Homo sapiens_hsa030301.42195550
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.42078064
25Collecting duct acid secretion_Homo sapiens_hsa049661.41916286
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.41879938
27RNA transport_Homo sapiens_hsa030131.39229509
28Vitamin B6 metabolism_Homo sapiens_hsa007501.37055571
29Fatty acid elongation_Homo sapiens_hsa000621.36317213
30Purine metabolism_Homo sapiens_hsa002301.33589177
31Selenocompound metabolism_Homo sapiens_hsa004501.24387152
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.23680879
33Vibrio cholerae infection_Homo sapiens_hsa051101.23011345
34Cardiac muscle contraction_Homo sapiens_hsa042601.17504895
35RNA degradation_Homo sapiens_hsa030181.17099367
36Mismatch repair_Homo sapiens_hsa034301.16744490
37Butanoate metabolism_Homo sapiens_hsa006501.11713713
38Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.11302508
39Base excision repair_Homo sapiens_hsa034101.04696246
40Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.97478869
41Rheumatoid arthritis_Homo sapiens_hsa053230.93803432
42Sulfur metabolism_Homo sapiens_hsa009200.93108759
43Tyrosine metabolism_Homo sapiens_hsa003500.91124101
44Metabolic pathways_Homo sapiens_hsa011000.88298777
45Maturity onset diabetes of the young_Homo sapiens_hsa049500.88163393
46Tryptophan metabolism_Homo sapiens_hsa003800.86026859
47Nitrogen metabolism_Homo sapiens_hsa009100.83031589
48Epstein-Barr virus infection_Homo sapiens_hsa051690.82063922
49Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.80393187
50Ether lipid metabolism_Homo sapiens_hsa005650.78808024
51Pyruvate metabolism_Homo sapiens_hsa006200.77203523
52Phagosome_Homo sapiens_hsa041450.77086998
53Glutathione metabolism_Homo sapiens_hsa004800.76915605
54Cysteine and methionine metabolism_Homo sapiens_hsa002700.76551159
55Regulation of autophagy_Homo sapiens_hsa041400.75912364
56Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.72248115
57Phenylalanine metabolism_Homo sapiens_hsa003600.72079898
58Arachidonic acid metabolism_Homo sapiens_hsa005900.70569751
59Sphingolipid metabolism_Homo sapiens_hsa006000.70448150
60Sulfur relay system_Homo sapiens_hsa041220.68718616
61Asthma_Homo sapiens_hsa053100.66777684
62Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.64717462
63Peroxisome_Homo sapiens_hsa041460.62254871
64Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.60829540
65Pentose and glucuronate interconversions_Homo sapiens_hsa000400.59630018
66Oocyte meiosis_Homo sapiens_hsa041140.58334424
67Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.57565532
68Caffeine metabolism_Homo sapiens_hsa002320.57051354
69Cell cycle_Homo sapiens_hsa041100.54733752
70Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.54456957
71beta-Alanine metabolism_Homo sapiens_hsa004100.54059970
72Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52696448
73Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.52658548
74Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.51160047
75Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.50891392
76Arginine and proline metabolism_Homo sapiens_hsa003300.50636878
77Primary bile acid biosynthesis_Homo sapiens_hsa001200.50051781
78Retinol metabolism_Homo sapiens_hsa008300.49000395
79p53 signaling pathway_Homo sapiens_hsa041150.47855597
80Drug metabolism - other enzymes_Homo sapiens_hsa009830.47268803
81Linoleic acid metabolism_Homo sapiens_hsa005910.46590684
82Fatty acid degradation_Homo sapiens_hsa000710.44090225
83Serotonergic synapse_Homo sapiens_hsa047260.43451150
84One carbon pool by folate_Homo sapiens_hsa006700.43344641
85Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.42891304
86Systemic lupus erythematosus_Homo sapiens_hsa053220.42398337
87mRNA surveillance pathway_Homo sapiens_hsa030150.41998032
88Fanconi anemia pathway_Homo sapiens_hsa034600.41682375
89Allograft rejection_Homo sapiens_hsa053300.40647558
90Other glycan degradation_Homo sapiens_hsa005110.39392992
91Legionellosis_Homo sapiens_hsa051340.39077694
92Histidine metabolism_Homo sapiens_hsa003400.38149529
93Olfactory transduction_Homo sapiens_hsa047400.37922330
94N-Glycan biosynthesis_Homo sapiens_hsa005100.37635284
95Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.37629630
96Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.37627005
97Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36808051
982-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.36026070
99Taste transduction_Homo sapiens_hsa047420.35953046
100Carbon metabolism_Homo sapiens_hsa012000.35868506
101Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.35199823
102Fatty acid metabolism_Homo sapiens_hsa012120.34737602
103Nicotine addiction_Homo sapiens_hsa050330.32170935
104Basal cell carcinoma_Homo sapiens_hsa052170.32127060
105Propanoate metabolism_Homo sapiens_hsa006400.30372265
106alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.28458019
107Hedgehog signaling pathway_Homo sapiens_hsa043400.28149159
108Chemical carcinogenesis_Homo sapiens_hsa052040.27984610
109Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.27688646
110TGF-beta signaling pathway_Homo sapiens_hsa043500.27506830
111Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.27452850
112Biosynthesis of amino acids_Homo sapiens_hsa012300.27217175
113Alcoholism_Homo sapiens_hsa050340.25616904
114Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.25281103
115Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.23860097
116Vitamin digestion and absorption_Homo sapiens_hsa049770.23432725
117Type I diabetes mellitus_Homo sapiens_hsa049400.23002197
118Pentose phosphate pathway_Homo sapiens_hsa000300.22478561
119Fat digestion and absorption_Homo sapiens_hsa049750.20034349
120Steroid hormone biosynthesis_Homo sapiens_hsa001400.19241229
121Synaptic vesicle cycle_Homo sapiens_hsa047210.16276510
122Autoimmune thyroid disease_Homo sapiens_hsa053200.12641912
123Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.11885349
124Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.11791984
125Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.10226497
126Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.09643141
127Malaria_Homo sapiens_hsa051440.09495631
128GABAergic synapse_Homo sapiens_hsa047270.09218766
129Phototransduction_Homo sapiens_hsa047440.08770189

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