TATDN2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of erythrocyte differentiation (GO:0045647)4.75865740
2positive regulation of gamma-delta T cell activation (GO:0046645)3.85256369
3regulation of interleukin-12 biosynthetic process (GO:0045075)3.78783095
4modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.63305315
5modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.63305315
6positive regulation by organism of defense response of other organism involved in symbiotic interact3.63305315
7modulation by symbiont of host immune response (GO:0052553)3.63305315
8positive regulation by symbiont of host defense response (GO:0052509)3.63305315
9modulation by symbiont of host defense response (GO:0052031)3.63305315
10low-density lipoprotein particle clearance (GO:0034383)3.60522142
11regulation of gamma-delta T cell differentiation (GO:0045586)3.59722455
12response to peptidoglycan (GO:0032494)3.55543626
13nuclear pore complex assembly (GO:0051292)3.52620830
14negative regulation of cell killing (GO:0031342)3.50838775
15negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.50838775
16positive regulation of histone deacetylation (GO:0031065)3.42814813
17leukocyte aggregation (GO:0070486)3.41129451
18protein localization to endosome (GO:0036010)3.39724130
19regulation of gamma-delta T cell activation (GO:0046643)3.38435403
20regulation of histone H3-K27 methylation (GO:0061085)3.34955435
21positive thymic T cell selection (GO:0045059)3.33902764
22positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.30021009
23regulation of cholesterol storage (GO:0010885)3.27971122
24antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.24138372
25antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.24138372
26apoptotic cell clearance (GO:0043277)3.21938373
27antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.17378843
28regulation of interferon-beta biosynthetic process (GO:0045357)3.14268544
29detection of other organism (GO:0098543)3.09993097
30T cell selection (GO:0045058)3.05758947
31positive regulation of p38MAPK cascade (GO:1900745)3.04405432
32detection of bacterium (GO:0016045)3.03318870
33nuclear pore organization (GO:0006999)3.01947470
34positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.00780354
35NLS-bearing protein import into nucleus (GO:0006607)2.99139667
36antigen processing and presentation of endogenous antigen (GO:0019883)2.94348608
373-UTR-mediated mRNA stabilization (GO:0070935)2.89569335
38modulation by virus of host process (GO:0019054)2.89519470
39regulation of type I interferon-mediated signaling pathway (GO:0060338)2.88909677
40positive regulation of Cdc42 GTPase activity (GO:0043089)2.86551738
41positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.85083774
42cytoplasmic mRNA processing body assembly (GO:0033962)2.84507684
43positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.84282667
44B cell receptor signaling pathway (GO:0050853)2.84125893
45macrophage activation involved in immune response (GO:0002281)2.81765659
46embryonic process involved in female pregnancy (GO:0060136)2.81063001
47regulation of early endosome to late endosome transport (GO:2000641)2.81036951
48positive regulation of lipid storage (GO:0010884)2.79336829
49regulation of translational termination (GO:0006449)2.78479447
50lipopolysaccharide-mediated signaling pathway (GO:0031663)2.77900909
51regulation of defense response to virus by virus (GO:0050690)2.77869837
52growth hormone receptor signaling pathway (GO:0060396)2.76387293
53histone H3-K36 demethylation (GO:0070544)2.75117258
54cell adhesion mediated by integrin (GO:0033627)2.74268935
55regulation of leukocyte degranulation (GO:0043300)2.73878747
56pore complex assembly (GO:0046931)2.70682166
57JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.68249683
58response to laminar fluid shear stress (GO:0034616)2.66621489
59neutrophil activation involved in immune response (GO:0002283)2.66103130
60pre-miRNA processing (GO:0031054)2.65149711
61germinal center formation (GO:0002467)2.64302734
62regulation of T-helper 2 cell differentiation (GO:0045628)2.63407373
63barbed-end actin filament capping (GO:0051016)2.61993239
64regulation of NFAT protein import into nucleus (GO:0051532)2.61009537
65regulation of integrin activation (GO:0033623)2.58986377
66I-kappaB phosphorylation (GO:0007252)2.57935305
67regulation of cholesterol homeostasis (GO:2000188)2.57798499
68regulation of ARF protein signal transduction (GO:0032012)2.57572029
69response to interleukin-15 (GO:0070672)2.56885581
70cellular extravasation (GO:0045123)2.54222392
71negative regulation of interleukin-12 production (GO:0032695)2.54200792
72negative regulation of fatty acid transport (GO:2000192)2.54167878
73positive regulation of keratinocyte differentiation (GO:0045618)2.53414861
74regulation of membrane protein ectodomain proteolysis (GO:0051043)2.53292987
75detection of external biotic stimulus (GO:0098581)2.52850455
76mRNA stabilization (GO:0048255)2.51806141
77RNA stabilization (GO:0043489)2.51806141
78positive regulation of interferon-alpha production (GO:0032727)2.51630174
79signal complex assembly (GO:0007172)2.51415513
80response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.51181548
81response to host immune response (GO:0052572)2.51181548
82Golgi transport vesicle coating (GO:0048200)2.50712125
83COPI coating of Golgi vesicle (GO:0048205)2.50712125
84thymic T cell selection (GO:0045061)2.47618016
85maternal placenta development (GO:0001893)2.47429941
86peptidyl-lysine dimethylation (GO:0018027)2.47350329
87focal adhesion assembly (GO:0048041)2.46087828
88cell-substrate adherens junction assembly (GO:0007045)2.46087828
89regulation of fatty acid beta-oxidation (GO:0031998)2.45372101
90activation of Rac GTPase activity (GO:0032863)2.45162789
91positive regulation of Rap GTPase activity (GO:0032854)2.43202684
92heterochromatin organization (GO:0070828)2.42534693
93regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.42349912
94regulation of extracellular matrix disassembly (GO:0010715)2.41512358
95regulation of interferon-alpha production (GO:0032647)2.41056898
96regulation of myeloid leukocyte mediated immunity (GO:0002886)2.40892978
97tolerance induction (GO:0002507)2.40784100
98intracellular estrogen receptor signaling pathway (GO:0030520)2.40038490
99cortical actin cytoskeleton organization (GO:0030866)2.39408059
100positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.38823000
101negative regulation of leukocyte mediated immunity (GO:0002704)2.38305339
102pinocytosis (GO:0006907)2.37620202
103antigen processing and presentation via MHC class Ib (GO:0002475)2.37568923
104L-alpha-amino acid transmembrane transport (GO:1902475)2.36698841
105phospholipid homeostasis (GO:0055091)2.35716334
106negative regulation of toll-like receptor signaling pathway (GO:0034122)2.35559632
107regulation of translational fidelity (GO:0006450)2.35503490
108regulation of RNA export from nucleus (GO:0046831)2.35123320
109negative regulation of lipid transport (GO:0032369)2.34485201
110regulation of B cell receptor signaling pathway (GO:0050855)2.34075799
111regulation of mammary gland epithelial cell proliferation (GO:0033599)2.32628288
112regulation of p38MAPK cascade (GO:1900744)2.32245854
113positive regulation of protein deacetylation (GO:0090312)2.32232388
114regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.31807767
115type I interferon signaling pathway (GO:0060337)2.31641263
116cellular response to type I interferon (GO:0071357)2.31641263
117negative regulation of cell size (GO:0045792)2.31187542
118response to type I interferon (GO:0034340)2.30788696
119myeloid dendritic cell differentiation (GO:0043011)2.30745792
120regulation of mast cell degranulation (GO:0043304)2.30149715
121positive regulation of B cell differentiation (GO:0045579)2.30003461
122cell-substrate junction assembly (GO:0007044)2.29867944
123negative regulation of lymphocyte mediated immunity (GO:0002707)2.29682282
124regulation of regulated secretory pathway (GO:1903305)2.28939185
125positive T cell selection (GO:0043368)2.28434631
126T cell migration (GO:0072678)2.28273736
127immunoglobulin mediated immune response (GO:0016064)2.28093867
128epithelial cell differentiation involved in prostate gland development (GO:0060742)2.26864839
129cellular response to growth hormone stimulus (GO:0071378)2.26706129
130activation of JUN kinase activity (GO:0007257)2.26215778
131response to UV-C (GO:0010225)2.25775956
132stress fiber assembly (GO:0043149)2.23923309
133apoptotic process involved in morphogenesis (GO:0060561)2.22935880
134regulation of nucleobase-containing compound transport (GO:0032239)2.22806266
135negative thymic T cell selection (GO:0045060)2.21896036
136hepatocyte apoptotic process (GO:0097284)2.21575432
137modulation by symbiont of host cellular process (GO:0044068)2.20190993
138mannose metabolic process (GO:0006013)2.19676159
139positive regulation of fatty acid beta-oxidation (GO:0032000)2.17509200
140adherens junction assembly (GO:0034333)2.17263450
141embryonic placenta development (GO:0001892)2.16159778
142negative regulation of granulocyte differentiation (GO:0030853)2.15076481
143response to host (GO:0075136)2.14847468
144response to host defenses (GO:0052200)2.14847468
145response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.14847468
146negative regulation of lipid storage (GO:0010888)2.14819746
147dosage compensation (GO:0007549)2.14411594
148natural killer cell differentiation (GO:0001779)2.14062134
149regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.13992219
150modification by symbiont of host morphology or physiology (GO:0044003)2.13534297
151response to muramyl dipeptide (GO:0032495)2.13454233
152NIK/NF-kappaB signaling (GO:0038061)2.12967412
153negative T cell selection (GO:0043383)2.12142195
154macroautophagy (GO:0016236)2.11753704
155pentose-phosphate shunt (GO:0006098)2.11305650
156germ cell migration (GO:0008354)2.10759168

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse4.25855070
2EGR1_19374776_ChIP-ChIP_THP-1_Human3.85377899
3E2F7_22180533_ChIP-Seq_HELA_Human3.36813175
4MYC_22102868_ChIP-Seq_BL_Human3.05235479
5FOXM1_23109430_ChIP-Seq_U2OS_Human2.78201112
6STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.71495645
7IRF8_22096565_ChIP-ChIP_GC-B_Human2.51627518
8STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.34525246
9ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.29209770
10TCF7_22412390_ChIP-Seq_EML_Mouse2.28838404
11VDR_21846776_ChIP-Seq_THP-1_Human2.27534967
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.16167951
13FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.15949976
14* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.15780299
15NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.12108984
16KDM2B_26808549_Chip-Seq_DND41_Human2.06376807
17BRD4_27068464_Chip-Seq_AML-cells_Mouse2.04387541
18KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.03899015
19MYB_21317192_ChIP-Seq_ERMYB_Mouse2.00731346
20* PPARA_22158963_ChIP-Seq_LIVER_Mouse1.99717597
21KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.98726504
22KDM2B_26808549_Chip-Seq_SUP-B15_Human1.94854221
23* IRF8_27001747_Chip-Seq_BMDM_Mouse1.94127668
24IRF8_21731497_ChIP-ChIP_J774_Mouse1.92535717
25MAF_26560356_Chip-Seq_TH1_Human1.90803843
26CLOCK_20551151_ChIP-Seq_293T_Human1.87804996
27RXR_22158963_ChIP-Seq_LIVER_Mouse1.87537168
28ELK3_25401928_ChIP-Seq_HUVEC_Human1.86175707
29PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.85573858
30* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.81229323
31LXR_22158963_ChIP-Seq_LIVER_Mouse1.73380987
32KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.72300574
33* UTX_26944678_Chip-Seq_JUKART_Human1.68098828
34STAT6_21828071_ChIP-Seq_BEAS2B_Human1.66997945
35NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.66922876
36EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.66863628
37STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.65832549
38RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.64253388
39Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.64245305
40VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.59580172
41ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.58520092
42* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.54435485
43* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.53779271
44MYB_26560356_Chip-Seq_TH1_Human1.53246630
45TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52489635
46FOXO3_23340844_ChIP-Seq_DLD1_Human1.50785197
47TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50448955
48VDR_24763502_ChIP-Seq_THP-1_Human1.50094017
49* MYB_26560356_Chip-Seq_TH2_Human1.45896366
50SPI1_23127762_ChIP-Seq_K562_Human1.44792976
51HIF1A_21447827_ChIP-Seq_MCF-7_Human1.44682429
52P300_27058665_Chip-Seq_ZR-75-30cells_Human1.43221113
53IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.42622609
54ATF3_27146783_Chip-Seq_COLON_Human1.41677959
55TP63_17297297_ChIP-ChIP_HaCaT_Human1.41053585
56* RUNX1_22412390_ChIP-Seq_EML_Mouse1.40435734
57KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.36693001
58CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.36664313
59DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.36364445
60EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.36016682
61RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.34936722
62* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.34439673
63ZNF263_19887448_ChIP-Seq_K562_Human1.33198523
64GATA1_22383799_ChIP-Seq_G1ME_Mouse1.32560437
65RACK7_27058665_Chip-Seq_MCF-7_Human1.32192944
66NCOR1_26117541_ChIP-Seq_K562_Human1.28773137
67KDM2B_26808549_Chip-Seq_JURKAT_Human1.28676644
68CTCF_27219007_Chip-Seq_ERYTHROID_Human1.28176639
69TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.27558509
70* RUNX_20019798_ChIP-Seq_JUKART_Human1.27164410
71RARG_19884340_ChIP-ChIP_MEFs_Mouse1.26700504
72NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.26018777
73LXR_22292898_ChIP-Seq_THP-1_Human1.25080656
74ZFP281_18757296_ChIP-ChIP_E14_Mouse1.23836027
75TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.22339679
76* PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.21709121
77STAT3_1855785_ChIP-Seq_MESCs_Mouse1.21563230
78CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.21440998
79ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.21378090
80PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.18732748
81SCL_19346495_ChIP-Seq_HPC-7_Human1.18656960
82GATA1_19941827_ChIP-Seq_MEL_Mouse1.18041894
83SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.16770481
84STAT4_19710469_ChIP-ChIP_TH1__Mouse1.16375439
85MAF_26560356_Chip-Seq_TH2_Human1.15014849
86* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.15009935
87FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.14977022
88SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.14705906
89GATA6_25053715_ChIP-Seq_YYC3_Human1.14098344
90GATA1_19941826_ChIP-Seq_K562_Human1.13493279
91EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.13179175
92SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13065786
93ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.12933735
94SA1_27219007_Chip-Seq_ERYTHROID_Human1.09720522
95THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.09023821
96PU_27001747_Chip-Seq_BMDM_Mouse1.08683188
97NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.08635411
98TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.08564458
99CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.08323818
100* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.07988759
101IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.07792103
102GATA1_22025678_ChIP-Seq_K562_Human1.07115358
103WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.06874986
104SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.06726553
105PU.1_20513432_ChIP-Seq_Bcells_Mouse1.06279018
106CIITA_25753668_ChIP-Seq_RAJI_Human1.04553394
107ESR2_21235772_ChIP-Seq_MCF-7_Human1.04085270
108UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.03925541
109CREB1_26743006_Chip-Seq_LNCaP_Human1.03697977
110* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.03441691
111BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.03159419
112PPAR_26484153_Chip-Seq_NCI-H1993_Human1.02991382
113FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.02282476
114FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.02003834
115* TET1_21451524_ChIP-Seq_MESCs_Mouse1.01396921
116CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.00181303
117HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.99980901
118* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.99551988
119* GATA3_27048872_Chip-Seq_THYMUS_Human0.99340370
120KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.98325071
121* KDM2B_26808549_Chip-Seq_K562_Human0.98276343
122TFEB_21752829_ChIP-Seq_HELA_Human0.97846774
123SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.97245529
124SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.97245529
125GATA2_22383799_ChIP-Seq_G1ME_Mouse0.94585343
126SPI1_23547873_ChIP-Seq_NB4_Human0.94475092
127GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94470588
128GATA2_19941826_ChIP-Seq_K562_Human0.93534817
129RUNX1_27514584_Chip-Seq_MCF-7_Human0.92771458
130* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.90892705
131DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.90561515
132RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.89407089

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.72119366
2MP0003303_peritoneal_inflammation3.34577913
3MP0005451_abnormal_body_composition3.06249698
4MP0003300_gastrointestinal_ulcer3.00721424
5MP0010352_gastrointestinal_tract_polyps2.63505123
6MP0008260_abnormal_autophagy2.41732175
7MP0005076_abnormal_cell_differentiation2.39166562
8MP0003566_abnormal_cell_adhesion2.34952622
9MP0010307_abnormal_tumor_latency2.28479187
10MP0000569_abnormal_digit_pigmentation2.27543049
11MP0003436_decreased_susceptibility_to2.13412356
12MP0004510_myositis2.04857623
13MP0009840_abnormal_foam_cell2.02231683
14MP0004185_abnormal_adipocyte_glucose1.93454143
15MP0003191_abnormal_cellular_cholesterol1.83197561
16MP0009278_abnormal_bone_marrow1.82553562
17MP0005058_abnormal_lysosome_morphology1.82424402
18MP0001835_abnormal_antigen_presentation1.81199222
19MP0004947_skin_inflammation1.76112815
20MP0010234_abnormal_vibrissa_follicle1.75436118
21MP0005360_urolithiasis1.71305436
22MP0003172_abnormal_lysosome_physiology1.67958725
23MP0000685_abnormal_immune_system1.64583617
24MP0002877_abnormal_melanocyte_morpholog1.58769760
25MP0001800_abnormal_humoral_immune1.57324564
26MP0008961_abnormal_basal_metabolism1.57271819
27MP0005387_immune_system_phenotype1.55101806
28MP0001790_abnormal_immune_system1.55101806
29MP0004381_abnormal_hair_follicle1.53030710
30MP0002166_altered_tumor_susceptibility1.49579646
31MP0002139_abnormal_hepatobiliary_system1.49070400
32MP0005666_abnormal_adipose_tissue1.45390826
33MP0003091_abnormal_cell_migration1.44272009
34MP0003724_increased_susceptibility_to1.44271082
35MP0002452_abnormal_antigen_presenting1.44224139
36MP0005464_abnormal_platelet_physiology1.44201424
37MP0002009_preneoplasia1.41341096
38MP0005023_abnormal_wound_healing1.40657916
39MP0004130_abnormal_muscle_cell1.37234285
40MP0005000_abnormal_immune_tolerance1.36299652
41MP0006082_CNS_inflammation1.35148523
42MP0002419_abnormal_innate_immunity1.34637968
43MP0003448_altered_tumor_morphology1.34282833
44MP0005409_darkened_coat_color1.33466389
45MP0000609_abnormal_liver_physiology1.31892507
46MP0002405_respiratory_system_inflammati1.31774927
47MP0000490_abnormal_crypts_of1.29886474
48MP0002723_abnormal_immune_serum1.26166944
49MP0005310_abnormal_salivary_gland1.24937518
50MP0003252_abnormal_bile_duct1.24713252
51MP0008438_abnormal_cutaneous_collagen1.24337485
52MP0002148_abnormal_hypersensitivity_rea1.23227265
53MP0004808_abnormal_hematopoietic_stem1.22883740
54MP0001545_abnormal_hematopoietic_system1.21997636
55MP0005397_hematopoietic_system_phenotyp1.21997636
56MP0001348_abnormal_lacrimal_gland1.21445618
57MP0002398_abnormal_bone_marrow1.20567864
58MP0002420_abnormal_adaptive_immunity1.20401277
59MP0001819_abnormal_immune_cell1.20219930
60MP0000733_abnormal_muscle_development1.19228607
61MP0002796_impaired_skin_barrier1.16172911
62MP0003866_abnormal_defecation1.15701968
63MP0003453_abnormal_keratinocyte_physiol1.15421975
64MP0000604_amyloidosis1.15237802
65MP0002006_tumorigenesis1.12760293
66MP0010155_abnormal_intestine_physiology1.11989669
67MP0001873_stomach_inflammation1.11828591
68MP0000689_abnormal_spleen_morphology1.11092656
69MP0005025_abnormal_response_to1.10960327
70MP0005257_abnormal_intraocular_pressure1.10682686
71MP0005365_abnormal_bile_salt1.10429024
72MP0001851_eye_inflammation1.09815394
73MP0005375_adipose_tissue_phenotype1.09771028
74MP0001845_abnormal_inflammatory_respons1.07310066
75MP0002396_abnormal_hematopoietic_system1.07074660
76MP0004264_abnormal_extraembryonic_tissu1.05352104
77MP0002722_abnormal_immune_system1.04154077
78MP0003045_fibrosis1.03846681
79MP0000716_abnormal_immune_system1.03375998
80MP0005621_abnormal_cell_physiology1.02877082
81MP0004858_abnormal_nervous_system1.02324150
82MP0001533_abnormal_skeleton_physiology1.01309160
83MP0010329_abnormal_lipoprotein_level1.00719895
84MP0003763_abnormal_thymus_physiology1.00624592
85MP0000858_altered_metastatic_potential0.99697957
86MP0001853_heart_inflammation0.99490323
87MP0005083_abnormal_biliary_tract0.98326811
88MP0002998_abnormal_bone_remodeling0.98000217
89MP0002138_abnormal_hepatobiliary_system0.97266724
90MP0001849_ear_inflammation0.95367059
91MP0003183_abnormal_peptide_metabolism0.93810230
92MP0002086_abnormal_extraembryonic_tissu0.93205734
93MP0002254_reproductive_system_inflammat0.92470302
94MP0010630_abnormal_cardiac_muscle0.91806050
95MP0000598_abnormal_liver_morphology0.91779133
96MP0002429_abnormal_blood_cell0.91673959
97MP0005670_abnormal_white_adipose0.91381277
98MP0004233_abnormal_muscle_weight0.91351379
99MP0000371_diluted_coat_color0.91318784
100MP0001958_emphysema0.90778838
101MP0000703_abnormal_thymus_morphology0.86902067
102MP0002088_abnormal_embryonic_growth/wei0.86573960
103MP0003984_embryonic_growth_retardation0.85925786
104MP0001730_embryonic_growth_arrest0.85312000
105MP0004197_abnormal_fetal_growth/weight/0.84399746
106MP0003329_amyloid_beta_deposits0.84397349
107MP0005671_abnormal_response_to0.83377597
108MP0009785_altered_susceptibility_to0.83236198
109MP0008469_abnormal_protein_level0.83144532
110MP0005085_abnormal_gallbladder_physiolo0.82447126
111MP0001915_intracranial_hemorrhage0.82049217
112MP0004087_abnormal_muscle_fiber0.81491444
113MP0009333_abnormal_splenocyte_physiolog0.81353860
114MP0003828_pulmonary_edema0.81228595
115MP0003111_abnormal_nucleus_morphology0.81141011
116MP0000678_abnormal_parathyroid_gland0.80288528
117MP0002060_abnormal_skin_morphology0.79618535
118MP0003075_altered_response_to0.77841148
119MP0003690_abnormal_glial_cell0.77677325
120MP0001672_abnormal_embryogenesis/_devel0.77430707
121MP0005380_embryogenesis_phenotype0.77430707
122MP0000465_gastrointestinal_hemorrhage0.76995179
123MP0009931_abnormal_skin_appearance0.75367380
124MP0000350_abnormal_cell_proliferation0.75269908
125MP0005166_decreased_susceptibility_to0.74834371
126MP0003656_abnormal_erythrocyte_physiolo0.74315312
127MP0005501_abnormal_skin_physiology0.74054001
128MP0000313_abnormal_cell_death0.73351476

Predicted human phenotypes

RankGene SetZ-score
1Cerebral aneurysm (HP:0004944)3.34305855
2Myocardial infarction (HP:0001658)3.33474130
3Eczematoid dermatitis (HP:0000976)3.06247195
4Increased density of long bones (HP:0006392)2.69864314
5Obstructive sleep apnea (HP:0002870)2.58360566
6Subacute progressive viral hepatitis (HP:0006572)2.51108772
7Increased connective tissue (HP:0009025)2.46574403
8Autoimmune thrombocytopenia (HP:0001973)2.42902392
9Ulnar bowing (HP:0003031)2.42669966
10Upper limb amyotrophy (HP:0009129)2.38832754
11Distal upper limb amyotrophy (HP:0007149)2.38832754
12Hematochezia (HP:0002573)2.38507153
13Frequent falls (HP:0002359)2.36561228
14Mitral valve prolapse (HP:0001634)2.35108016
15Increased IgE level (HP:0003212)2.33852175
16Recurrent gram-negative bacterial infections (HP:0005420)2.33375933
17Vertebral compression fractures (HP:0002953)2.33023097
18Spinal cord lesions (HP:0100561)2.32552867
19Syringomyelia (HP:0003396)2.32552867
20Hand muscle atrophy (HP:0009130)2.32397632
21Recurrent abscess formation (HP:0002722)2.31113979
22Broad face (HP:0000283)2.28898044
23Osteolytic defects of the hand bones (HP:0009699)2.26418567
24Osteolytic defects of the phalanges of the hand (HP:0009771)2.26418567
25Recurrent bacterial skin infections (HP:0005406)2.26226458
26Persistence of primary teeth (HP:0006335)2.25868380
27Abnormal platelet volume (HP:0011876)2.23324373
28Asymmetry of the thorax (HP:0001555)2.23057007
29Abnormality of the fingertips (HP:0001211)2.21224773
30Increased mean platelet volume (HP:0011877)2.20236009
31Increased cerebral lipofuscin (HP:0011813)2.18411722
32Recurrent fungal infections (HP:0002841)2.18217781
33Slow saccadic eye movements (HP:0000514)2.13495892
34Recurrent viral infections (HP:0004429)2.12333390
35Aortic aneurysm (HP:0004942)2.11567112
36Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.09106490
37Arterial thrombosis (HP:0004420)2.08559300
38Colitis (HP:0002583)2.08459136
39Dysostosis multiplex (HP:0000943)2.08390169
40Obstructive lung disease (HP:0006536)2.08225091
41Chronic obstructive pulmonary disease (HP:0006510)2.08225091
42Recurrent skin infections (HP:0001581)2.08064296
43Aneurysm (HP:0002617)2.07886039
44Meningitis (HP:0001287)2.07543755
45Abnormality of the Achilles tendon (HP:0005109)2.05054779
46Deep venous thrombosis (HP:0002625)2.03423994
47Global brain atrophy (HP:0002283)2.03361532
48Achilles tendon contracture (HP:0001771)2.01990099
49Gastrointestinal stroma tumor (HP:0100723)2.00337817
50Increased CSF protein (HP:0002922)2.00109516
51Esophageal varix (HP:0002040)1.99647618
52Pustule (HP:0200039)1.98876840
53Protrusio acetabuli (HP:0003179)1.98822350
54Cellulitis (HP:0100658)1.98622266
55Xanthomatosis (HP:0000991)1.97013506
56Upper motor neuron abnormality (HP:0002127)1.96807150
57Heterotopia (HP:0002282)1.95765412
58Segmental peripheral demyelination/remyelination (HP:0003481)1.92918160
59Macroorchidism (HP:0000053)1.92613681
60Long palpebral fissure (HP:0000637)1.92524593
61Neuronal loss in central nervous system (HP:0002529)1.92213413
62Dilatation of the ascending aorta (HP:0005111)1.91483090
63Hyperacusis (HP:0010780)1.90991959
64Asymmetric septal hypertrophy (HP:0001670)1.90262043
65Disinhibition (HP:0000734)1.90167375
66Gastrointestinal infarctions (HP:0005244)1.89516139
67Fatigue (HP:0012378)1.88196358
68Chronic mucocutaneous candidiasis (HP:0002728)1.86913608
69Recurrent cutaneous fungal infections (HP:0011370)1.86913608
70Flat acetabular roof (HP:0003180)1.86627670
71Peritonitis (HP:0002586)1.86619454
72Polygenic inheritance (HP:0010982)1.86599123
73Abnormality of oral frenula (HP:0000190)1.85551275
74Abnormal delayed hypersensitivity skin test (HP:0002963)1.83423932
75Genu recurvatum (HP:0002816)1.82812789
76Distal lower limb amyotrophy (HP:0008944)1.82673967
77Spastic diplegia (HP:0001264)1.82215250
78Abnormality of the thoracic spine (HP:0100711)1.81780595
79Ankyloglossia (HP:0010296)1.81350009
80Urethral obstruction (HP:0000796)1.78176721
81Metaphyseal cupping (HP:0003021)1.78053262
82Absent frontal sinuses (HP:0002688)1.77784373
83Hyporeflexia of lower limbs (HP:0002600)1.77418637
84Verrucae (HP:0200043)1.77105563
85Papilloma (HP:0012740)1.77105563
86Hyperparathyroidism (HP:0000843)1.76984468
87Spondylolisthesis (HP:0003302)1.76918538
88Long toe (HP:0010511)1.76067156
89Reticulocytosis (HP:0001923)1.74933890
90Vasculitis (HP:0002633)1.74626586
91Difficulty climbing stairs (HP:0003551)1.74383652
92Gingivitis (HP:0000230)1.74187557
93Emphysema (HP:0002097)1.74087805
94Interstitial pulmonary disease (HP:0006530)1.73586102
95Axonal loss (HP:0003447)1.73231992
96Insomnia (HP:0100785)1.71736430
97Resting tremor (HP:0002322)1.71411329
98Abnormal platelet function (HP:0011869)1.71156311
99Impaired platelet aggregation (HP:0003540)1.71156311
100Inflammation of the large intestine (HP:0002037)1.70443165
101Dislocated radial head (HP:0003083)1.70163560
102Osteomyelitis (HP:0002754)1.70129464
103Cutaneous melanoma (HP:0012056)1.69309921
104Centrally nucleated skeletal muscle fibers (HP:0003687)1.68709322
105Loss of speech (HP:0002371)1.67709503
106Gingival bleeding (HP:0000225)1.67083797
107Systemic lupus erythematosus (HP:0002725)1.66826860
108Difficulty running (HP:0009046)1.66791548
109Gastrointestinal inflammation (HP:0004386)1.66660748
110Deep palmar crease (HP:0006191)1.66473663
111Striae distensae (HP:0001065)1.66253846
112T lymphocytopenia (HP:0005403)1.66168710
113Mediastinal lymphadenopathy (HP:0100721)1.65541524
114Bone pain (HP:0002653)1.65522394
115Cerebral inclusion bodies (HP:0100314)1.65363524
116Myositis (HP:0100614)1.65288422
117Personality changes (HP:0000751)1.64288875
118Spontaneous hematomas (HP:0007420)1.64065668
119Cortical dysplasia (HP:0002539)1.64034420
120Supranuclear gaze palsy (HP:0000605)1.64028653
121Complement deficiency (HP:0004431)1.63991982
122Disproportionate tall stature (HP:0001519)1.63987311
123Polycythemia (HP:0001901)1.63948048
124Tetraparesis (HP:0002273)1.62175239
125Increased neuronal autofluorescent lipopigment (HP:0002074)1.61447190
126Abnormality of liposaccharide metabolism (HP:0010968)1.60765760
127Abnormality of glycosphingolipid metabolism (HP:0004343)1.60765760
128Abnormality of glycolipid metabolism (HP:0010969)1.60765760
129Hypoalphalipoproteinemia (HP:0003233)1.60663780
130Prolonged bleeding time (HP:0003010)1.60093896
131Mucopolysacchariduria (HP:0008155)1.60009396
132Urinary glycosaminoglycan excretion (HP:0003541)1.60009396
133Periodontitis (HP:0000704)1.59719400
134Abnormality of the distal phalanx of the thumb (HP:0009617)1.59209459
135Abnormality of macrophages (HP:0004311)1.59133523
136Dysmetric saccades (HP:0000641)1.58124419
137Stomatitis (HP:0010280)1.58087512
138Mitral regurgitation (HP:0001653)1.57995778
139Premature rupture of membranes (HP:0001788)1.57829235
140Shallow orbits (HP:0000586)1.57605953
141Increased variability in muscle fiber diameter (HP:0003557)1.57473238
142Exercise-induced muscle cramps (HP:0003710)1.57229858
143Abnormality of polysaccharide metabolism (HP:0011012)1.57050783
144Abnormality of glycosaminoglycan metabolism (HP:0004371)1.57050783
145Abnormality of mucopolysaccharide metabolism (HP:0011020)1.57050783
146Viral hepatitis (HP:0006562)1.56644451
147Thin bony cortex (HP:0002753)1.56611369
148Agammaglobulinemia (HP:0004432)1.56430544
149Hypertensive crisis (HP:0100735)1.56352691
150Coarse hair (HP:0002208)1.56297537
151Abnormality of complement system (HP:0005339)1.55091687
152Chest pain (HP:0100749)1.54470360
153Abnormality of T cell number (HP:0011839)1.54264102
154Bilateral sensorineural hearing impairment (HP:0008619)1.53807910
155Orchitis (HP:0100796)1.53312237
156Thick nail (HP:0001805)1.52726930
157Lymphangioma (HP:0100764)1.52600737

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PRPF4B4.31754035
2TRIB34.30520493
3PKN23.79023823
4SMG13.16102624
5CDK123.06826557
6TTN2.85728595
7MAP3K102.77291295
8EEF2K2.62027141
9MAP4K12.60970409
10ERN12.14402590
11RIPK12.10011236
12PTK61.85261378
13CAMK1D1.84397522
14STK101.83751540
15LATS11.62083001
16TYK21.59351329
17IRAK41.52004376
18SCYL21.48508607
19BMX1.47951031
20GRK61.46845776
21NME21.45835136
22JAK11.45169202
23SIK31.42200555
24ALK1.40007926
25MAP3K141.37709747
26CAMK1G1.36849810
27TAOK21.36760624
28LRRK21.35299502
29MAP2K31.34701299
30FGFR41.34318045
31TBK11.34214983
32SIK11.34202792
33JAK31.29351748
34TGFBR21.19329181
35PDGFRA1.19293417
36SIK21.18654339
37MAP3K31.17270848
38FGFR31.14128022
39MAP3K11.14022399
40CDK61.13968323
41EPHB11.13077524
42MTOR1.11743107
43TAOK11.11263579
44ZAP701.08579374
45STK31.08045352
46TAOK31.06720648
47BLK1.06719026
48CSK1.05387336
49NEK21.03226320
50HCK1.03213620
51CDC42BPA1.01198714
52PDGFRB1.01021273
53MARK20.99850350
54PIM10.99630177
55FES0.97994011
56JAK20.95749529
57CSF1R0.94683116
58CDK40.94248731
59ITK0.93641165
60MARK30.92802666
61TNK20.92772483
62ICK0.92407796
63PAK40.89095334
64CHUK0.88242505
65PRKD20.86740719
66IRAK20.86137492
67RPS6KA40.85736294
68DMPK0.83718106
69MAP3K80.81449937
70PRKD30.78261863
71HIPK20.77680138
72MAP3K70.76387836
73IKBKB0.76166123
74IRAK30.73818838
75NEK90.73729893
76PAK20.71699629
77RET0.70759363
78TESK20.68126420
79PRKCH0.67989574
80SGK30.67936570
81KIT0.67869097
82ARAF0.66816907
83MAPK120.66089353
84TRPM70.65873019
85STK40.64641921
86RIPK40.63690329
87KSR20.63018599
88FLT30.61673929
89IKBKE0.60290357
90PDK10.60122251
91YES10.58124414
92EGFR0.57980313
93KSR10.57615155
94MAP3K110.56246166
95EPHA20.56234319
96RAF10.55745381
97PTK20.55629748
98LCK0.54166638
99MELK0.54112577
100RPS6KA20.53536149
101NEK10.53039060
102MAP3K130.53019522
103RPS6KC10.52213281
104RPS6KL10.52213281
105GSK3A0.51252521
106CAMKK10.49340093
107LATS20.48572656
108BTK0.48337084
109PDPK10.47748120
110MAP2K20.47097551
111SYK0.46837963
112RPS6KB20.46012368
113MAP3K60.45926953
114MAPK110.44727585
115CDK90.44418219
116TXK0.44287615
117FGR0.42598780
118RPS6KA10.42270247
119NEK60.41826038
120MAPKAPK20.41347423
121MAP3K20.41252908
122TYRO30.41159749
123BRAF0.40906470
124STK380.40473775
125MST1R0.40095125
126TESK10.39347011
127ABL10.39055404
128DDR20.39003384
129CDK70.38709119
130CDC70.38235931
131MAP3K50.36629008
132PRKAA20.35350396
133MAP3K90.35129657
134LYN0.34735255
135BRD40.33421284

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.98076593
2Osteoclast differentiation_Homo sapiens_hsa043801.97410670
3Nitrogen metabolism_Homo sapiens_hsa009101.89911730
4Other glycan degradation_Homo sapiens_hsa005111.89311035
5B cell receptor signaling pathway_Homo sapiens_hsa046621.87021689
6Leishmaniasis_Homo sapiens_hsa051401.84318987
7Chronic myeloid leukemia_Homo sapiens_hsa052201.73445897
8Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.63502317
9Staphylococcus aureus infection_Homo sapiens_hsa051501.61969786
10NF-kappa B signaling pathway_Homo sapiens_hsa040641.56703725
11Lysine degradation_Homo sapiens_hsa003101.56080363
12mTOR signaling pathway_Homo sapiens_hsa041501.45119707
13Toxoplasmosis_Homo sapiens_hsa051451.42230339
14Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.38139538
15Thyroid cancer_Homo sapiens_hsa052161.37814604
16Insulin resistance_Homo sapiens_hsa049311.36537669
17Arginine biosynthesis_Homo sapiens_hsa002201.33935415
18Acute myeloid leukemia_Homo sapiens_hsa052211.30317943
19Small cell lung cancer_Homo sapiens_hsa052221.29927131
20Adipocytokine signaling pathway_Homo sapiens_hsa049201.29881787
21Antigen processing and presentation_Homo sapiens_hsa046121.28850909
22Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.28768467
23Apoptosis_Homo sapiens_hsa042101.27048922
24T cell receptor signaling pathway_Homo sapiens_hsa046601.25023965
25Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.24610647
26Toll-like receptor signaling pathway_Homo sapiens_hsa046201.22312915
27Pancreatic cancer_Homo sapiens_hsa052121.18670364
28Measles_Homo sapiens_hsa051621.16806499
29TNF signaling pathway_Homo sapiens_hsa046681.15826518
30Caffeine metabolism_Homo sapiens_hsa002321.15014984
31ErbB signaling pathway_Homo sapiens_hsa040121.14773617
32Tuberculosis_Homo sapiens_hsa051521.14686178
33Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.14616405
34AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.12635100
35Leukocyte transendothelial migration_Homo sapiens_hsa046701.12554963
36Non-small cell lung cancer_Homo sapiens_hsa052231.11813757
37Viral myocarditis_Homo sapiens_hsa054161.10587204
38Legionellosis_Homo sapiens_hsa051341.10379535
39Proteoglycans in cancer_Homo sapiens_hsa052051.07299807
40Phosphatidylinositol signaling system_Homo sapiens_hsa040701.05085242
41PPAR signaling pathway_Homo sapiens_hsa033201.05023541
42Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.04630380
43Sphingolipid signaling pathway_Homo sapiens_hsa040711.02977454
44Influenza A_Homo sapiens_hsa051641.02335423
45Neurotrophin signaling pathway_Homo sapiens_hsa047221.01830697
46Viral carcinogenesis_Homo sapiens_hsa052031.01451457
47Central carbon metabolism in cancer_Homo sapiens_hsa052301.01358471
48Amoebiasis_Homo sapiens_hsa051460.99670471
49MicroRNAs in cancer_Homo sapiens_hsa052060.98895165
50Prion diseases_Homo sapiens_hsa050200.98638989
51Phospholipase D signaling pathway_Homo sapiens_hsa040720.98482886
52Hepatitis B_Homo sapiens_hsa051610.98423387
532-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.97336552
54Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.96684620
55VEGF signaling pathway_Homo sapiens_hsa043700.96228060
56Complement and coagulation cascades_Homo sapiens_hsa046100.95986082
57Focal adhesion_Homo sapiens_hsa045100.95266267
58Type II diabetes mellitus_Homo sapiens_hsa049300.95213576
59GnRH signaling pathway_Homo sapiens_hsa049120.94665662
60Glycosaminoglycan degradation_Homo sapiens_hsa005310.94264924
61NOD-like receptor signaling pathway_Homo sapiens_hsa046210.93068256
62Choline metabolism in cancer_Homo sapiens_hsa052310.92997478
63Prolactin signaling pathway_Homo sapiens_hsa049170.91818601
64Lysosome_Homo sapiens_hsa041420.90721654
65Estrogen signaling pathway_Homo sapiens_hsa049150.89042394
66Allograft rejection_Homo sapiens_hsa053300.88885856
67Long-term potentiation_Homo sapiens_hsa047200.88875510
68Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.88112775
69HIF-1 signaling pathway_Homo sapiens_hsa040660.87472577
70Selenocompound metabolism_Homo sapiens_hsa004500.87409708
71Inositol phosphate metabolism_Homo sapiens_hsa005620.87332483
72Jak-STAT signaling pathway_Homo sapiens_hsa046300.87118050
73Endometrial cancer_Homo sapiens_hsa052130.86280105
74Adherens junction_Homo sapiens_hsa045200.85831551
75One carbon pool by folate_Homo sapiens_hsa006700.85050476
76Epstein-Barr virus infection_Homo sapiens_hsa051690.84831674
77Autoimmune thyroid disease_Homo sapiens_hsa053200.84546044
78Fatty acid degradation_Homo sapiens_hsa000710.82908163
79Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.82002524
80Graft-versus-host disease_Homo sapiens_hsa053320.80458449
81Platelet activation_Homo sapiens_hsa046110.79793050
82Longevity regulating pathway - mammal_Homo sapiens_hsa042110.79771318
83Carbohydrate digestion and absorption_Homo sapiens_hsa049730.79649029
84Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.79319060
85Pertussis_Homo sapiens_hsa051330.78742426
86Dorso-ventral axis formation_Homo sapiens_hsa043200.78335238
87Insulin signaling pathway_Homo sapiens_hsa049100.77381917
88Malaria_Homo sapiens_hsa051440.77228715
89Hepatitis C_Homo sapiens_hsa051600.76964647
90Chemokine signaling pathway_Homo sapiens_hsa040620.76554453
91Glioma_Homo sapiens_hsa052140.75691792
92Thyroid hormone signaling pathway_Homo sapiens_hsa049190.75509463
93Shigellosis_Homo sapiens_hsa051310.75112264
94Herpes simplex infection_Homo sapiens_hsa051680.74075901
95AMPK signaling pathway_Homo sapiens_hsa041520.73805727
96Renal cell carcinoma_Homo sapiens_hsa052110.73738129
97Systemic lupus erythematosus_Homo sapiens_hsa053220.73695435
98Salmonella infection_Homo sapiens_hsa051320.71704768
99Regulation of actin cytoskeleton_Homo sapiens_hsa048100.71395380
100Pentose phosphate pathway_Homo sapiens_hsa000300.70840489
101Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70790327
102Primary immunodeficiency_Homo sapiens_hsa053400.70332220
103FoxO signaling pathway_Homo sapiens_hsa040680.69677363
104HTLV-I infection_Homo sapiens_hsa051660.69001848
105Bladder cancer_Homo sapiens_hsa052190.68568789
106Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.68352661
107Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.67502020
108RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.66746473
109Colorectal cancer_Homo sapiens_hsa052100.66651200
110Primary bile acid biosynthesis_Homo sapiens_hsa001200.64524958
111Bile secretion_Homo sapiens_hsa049760.63099047
112Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.60878062
113Fatty acid biosynthesis_Homo sapiens_hsa000610.59428477
114Hematopoietic cell lineage_Homo sapiens_hsa046400.59132007
115Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.58442142
116Prostate cancer_Homo sapiens_hsa052150.58006996
117Carbon metabolism_Homo sapiens_hsa012000.56982125
118Biosynthesis of amino acids_Homo sapiens_hsa012300.56728492
119MAPK signaling pathway_Homo sapiens_hsa040100.56316282
120Notch signaling pathway_Homo sapiens_hsa043300.55851108
121Transcriptional misregulation in cancer_Homo sapiens_hsa052020.55673776
122Endocytosis_Homo sapiens_hsa041440.54126896
123Phagosome_Homo sapiens_hsa041450.52256843

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