TBC1D2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neutrophil activation involved in immune response (GO:0002283)4.43182789
2protein localization to endosome (GO:0036010)4.27262425
3neutrophil mediated immunity (GO:0002446)4.19258668
4antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.11107205
5antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.11107205
6glycosphingolipid catabolic process (GO:0046479)4.02660374
7response to fungus (GO:0009620)3.98968179
8defense response to fungus (GO:0050832)3.87689242
9pentose-phosphate shunt (GO:0006098)3.82991897
10leukocyte aggregation (GO:0070486)3.78866182
11negative regulation of phagocytosis (GO:0050765)3.74255629
12Arp2/3 complex-mediated actin nucleation (GO:0034314)3.67123288
13response to peptidoglycan (GO:0032494)3.67095990
14regulation of interferon-beta biosynthetic process (GO:0045357)3.65370351
15amino sugar catabolic process (GO:0046348)3.62995159
16leukocyte migration involved in inflammatory response (GO:0002523)3.62591389
17oligosaccharide catabolic process (GO:0009313)3.62444148
18production of molecular mediator involved in inflammatory response (GO:0002532)3.58583302
19glycolipid catabolic process (GO:0019377)3.57191873
20hemidesmosome assembly (GO:0031581)3.56166335
21cellular response to thyroid hormone stimulus (GO:0097067)3.49823471
22skin morphogenesis (GO:0043589)3.44446490
23modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.41321668
24positive regulation by organism of defense response of other organism involved in symbiotic interact3.41321668
25modulation by symbiont of host immune response (GO:0052553)3.41321668
26positive regulation by symbiont of host defense response (GO:0052509)3.41321668
27modulation by symbiont of host defense response (GO:0052031)3.41321668
28modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.41321668
29respiratory burst (GO:0045730)3.41171504
30neutrophil activation (GO:0042119)3.40258333
31NADPH regeneration (GO:0006740)3.30239436
32hypotonic response (GO:0006971)3.22962654
33antigen processing and presentation of endogenous antigen (GO:0019883)3.21684013
34cellular extravasation (GO:0045123)3.20444511
35granulocyte activation (GO:0036230)3.19081929
36low-density lipoprotein particle clearance (GO:0034383)3.19022432
37positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.11843582
38disruption of cells of other organism involved in symbiotic interaction (GO:0051818)3.09767871
39killing of cells in other organism involved in symbiotic interaction (GO:0051883)3.09767871
40ceramide catabolic process (GO:0046514)3.07166066
41positive regulation of monocyte chemotaxis (GO:0090026)3.06913360
42positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.06848984
43membrane raft organization (GO:0031579)3.06813165
44regulation of syncytium formation by plasma membrane fusion (GO:0060142)3.06293520
45sequestering of metal ion (GO:0051238)3.04100837
46macrophage differentiation (GO:0030225)3.02922059
47regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.02726103
48myeloid leukocyte mediated immunity (GO:0002444)3.02437299
49antigen processing and presentation via MHC class Ib (GO:0002475)3.01457006
50pinocytosis (GO:0006907)3.00243001
51response to thyroid hormone (GO:0097066)2.99275677
52negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.97294923
53regulation of integrin activation (GO:0033623)2.96367178
54wound healing, spreading of epidermal cells (GO:0035313)2.96202621
55interferon-gamma secretion (GO:0072643)2.92804899
56T cell apoptotic process (GO:0070231)2.92645682
57lipopolysaccharide-mediated signaling pathway (GO:0031663)2.92215496
58detection of molecule of bacterial origin (GO:0032490)2.92153300
59stress fiber assembly (GO:0043149)2.91942382
60leukocyte mediated cytotoxicity (GO:0001909)2.91012355
61regulation of monocyte chemotaxis (GO:0090025)2.90874295
62glucose catabolic process (GO:0006007)2.89564403
63negative regulation of nitric oxide biosynthetic process (GO:0045019)2.88029195
64dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.87295226
65detection of external biotic stimulus (GO:0098581)2.86500964
66detection of other organism (GO:0098543)2.85890403
67positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.85115161
68actin nucleation (GO:0045010)2.84957526
69macrophage activation involved in immune response (GO:0002281)2.84784357
70apoptotic cell clearance (GO:0043277)2.83725522
71negative regulation of erythrocyte differentiation (GO:0045647)2.80952738
72regulation of mast cell degranulation (GO:0043304)2.79965763
73regulation of leukocyte degranulation (GO:0043300)2.79251406
74response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.78728006
75response to host immune response (GO:0052572)2.78728006
76leukotriene metabolic process (GO:0006691)2.72628392
77apoptotic process involved in morphogenesis (GO:0060561)2.72355882
78regulation of superoxide anion generation (GO:0032928)2.71560088
79positive regulation of extracellular matrix organization (GO:1903055)2.71469831
80negative regulation of interleukin-12 production (GO:0032695)2.71024300
81response to host (GO:0075136)2.70162591
82response to host defenses (GO:0052200)2.70162591
83response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.70162591
84reactive oxygen species biosynthetic process (GO:1903409)2.69998404
85positive regulation of Cdc42 GTPase activity (GO:0043089)2.68632902
86regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.68600808
87leukocyte cell-cell adhesion (GO:0007159)2.67096086
88response to progesterone (GO:0032570)2.66945806
89immunoglobulin mediated immune response (GO:0016064)2.66937646
90regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.64740703
91hyaluronan catabolic process (GO:0030214)2.64547292
92NIK/NF-kappaB signaling (GO:0038061)2.64325160
93regulation of myeloid leukocyte mediated immunity (GO:0002886)2.63076187
94regulation of mast cell activation (GO:0033003)2.62506778
95response to muramyl dipeptide (GO:0032495)2.61430205
96regulation of mast cell activation involved in immune response (GO:0033006)2.61418870
97hepatocyte apoptotic process (GO:0097284)2.61297288
98negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.60560334
99regulation of mononuclear cell migration (GO:0071675)2.60271682
100surfactant homeostasis (GO:0043129)2.59507485
101positive regulation of receptor recycling (GO:0001921)2.58506299
102mannose metabolic process (GO:0006013)2.57739542
103regulation of early endosome to late endosome transport (GO:2000641)2.57713933
104endodermal cell differentiation (GO:0035987)2.57222983
105virion attachment to host cell (GO:0019062)2.56243010
106adhesion of symbiont to host cell (GO:0044650)2.56243010
107epithelial cell differentiation involved in prostate gland development (GO:0060742)2.56084473
108cell-substrate junction assembly (GO:0007044)2.54682451
109peptide catabolic process (GO:0043171)2.52700263
110antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.52220161
111lymphocyte apoptotic process (GO:0070227)2.50800846
112cell adhesion mediated by integrin (GO:0033627)2.50481320
113negative regulation of interleukin-8 production (GO:0032717)2.50409615
114negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.49359233
115negative regulation of cell killing (GO:0031342)2.49359233
116membrane lipid catabolic process (GO:0046466)2.49195491
117wound healing, spreading of cells (GO:0044319)2.48409528
118COPI coating of Golgi vesicle (GO:0048205)2.48344508
119Golgi transport vesicle coating (GO:0048200)2.48344508
120response to laminar fluid shear stress (GO:0034616)2.46613517
121decidualization (GO:0046697)2.45778137
122sphingolipid catabolic process (GO:0030149)2.44568754
123cellular response to zinc ion (GO:0071294)2.44493905
124positive regulation of cellular amide metabolic process (GO:0034250)2.44414038
125positive regulation of mast cell activation involved in immune response (GO:0033008)2.44331815
126positive regulation of mast cell degranulation (GO:0043306)2.44331815
127regulation of regulated secretory pathway (GO:1903305)2.44100430
128regulation of B cell receptor signaling pathway (GO:0050855)2.44056576
129positive regulation of gamma-delta T cell activation (GO:0046645)2.43865657
130response to magnesium ion (GO:0032026)2.43271026
131detection of biotic stimulus (GO:0009595)2.43159987
132positive regulation of interferon-alpha production (GO:0032727)2.42639191
133regulation of membrane protein ectodomain proteolysis (GO:0051043)2.42360139
134regulation of macrophage chemotaxis (GO:0010758)2.41772445
135cellular response to arsenic-containing substance (GO:0071243)2.41298600
136regulation of cholesterol storage (GO:0010885)2.41235878
137myeloid cell activation involved in immune response (GO:0002275)2.39994111
138negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.39865237
139positive regulation of leukocyte degranulation (GO:0043302)2.39685128
140protein localization to kinetochore (GO:0034501)2.39680309
141barbed-end actin filament capping (GO:0051016)2.39383350
142substrate-dependent cell migration (GO:0006929)2.39310560
143regulation of T-helper 2 cell differentiation (GO:0045628)2.36353123
144positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.36237586
145regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.35829198
146angiogenesis involved in wound healing (GO:0060055)2.35326391
147desmosome organization (GO:0002934)2.35232635
148regulation of phagocytosis (GO:0050764)2.34509752
149detection of bacterium (GO:0016045)2.33769119
150negative regulation of granulocyte differentiation (GO:0030853)2.33293685
151negative regulation of growth of symbiont in host (GO:0044130)2.33284251
152negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.33284251
153modulation of growth of symbiont involved in interaction with host (GO:0044144)2.33284251
154regulation of growth of symbiont in host (GO:0044126)2.33284251
155positive regulation of mast cell activation (GO:0033005)2.32584677
156heterochromatin organization (GO:0070828)2.32350041
157regulation of macrophage cytokine production (GO:0010935)2.32342188
158positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.31670019
159positive regulation of osteoblast proliferation (GO:0033690)2.31096414
160N-acetylneuraminate metabolic process (GO:0006054)2.31074973
161negative regulation of protein localization to plasma membrane (GO:1903077)2.30603463

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.23678769
2E2F7_22180533_ChIP-Seq_HELA_Human3.74846344
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.10868686
4MYB_21317192_ChIP-Seq_ERMYB_Mouse3.10593768
5FOXM1_23109430_ChIP-Seq_U2OS_Human2.77340268
6IRF8_21731497_ChIP-ChIP_J774_Mouse2.62563660
7VDR_21846776_ChIP-Seq_THP-1_Human2.62216677
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.49968802
9BP1_19119308_ChIP-ChIP_Hs578T_Human2.36120429
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.30881637
11NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.27243122
12STAT6_21828071_ChIP-Seq_BEAS2B_Human2.25870473
13BRD4_27068464_Chip-Seq_AML-cells_Mouse2.24000778
14IRF8_22096565_ChIP-ChIP_GC-B_Human2.14899230
15NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.12448291
16MYC_22102868_ChIP-Seq_BL_Human2.11675683
17SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.10651628
18EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.07272932
19THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.92188057
20SPI1_23547873_ChIP-Seq_NB4_Human1.88296714
21IRF8_27001747_Chip-Seq_BMDM_Mouse1.87582831
22RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.87158331
23ELK3_25401928_ChIP-Seq_HUVEC_Human1.87153830
24VDR_24763502_ChIP-Seq_THP-1_Human1.85599609
25TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.81739639
26SCL_19346495_ChIP-Seq_HPC-7_Human1.81220075
27RARG_19884340_ChIP-ChIP_MEFs_Mouse1.79315612
28SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.77153497
29ESR2_21235772_ChIP-Seq_MCF-7_Human1.76603599
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.67683601
31RUNX1_22412390_ChIP-Seq_EML_Mouse1.66025817
32STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.65545437
33* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.64751690
34TCF7_22412390_ChIP-Seq_EML_Mouse1.60190157
35RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.57102560
36MAF_26560356_Chip-Seq_TH1_Human1.56952225
37TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.52835760
38SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.52549002
39FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.48866891
40CLOCK_20551151_ChIP-Seq_293T_Human1.47870485
41STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.46868360
42SPI1_23127762_ChIP-Seq_K562_Human1.44385310
43KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.41014688
44STAT3_1855785_ChIP-Seq_MESCs_Mouse1.40252946
45UTX_26944678_Chip-Seq_JUKART_Human1.40069849
46VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.40039427
47KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.38853010
48TFEB_21752829_ChIP-Seq_HELA_Human1.37550261
49UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.37338613
50RACK7_27058665_Chip-Seq_MCF-7_Human1.37074692
51TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.35314082
52FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.34749649
53TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.34319954
54P300_27058665_Chip-Seq_ZR-75-30cells_Human1.33570037
55SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.33002784
56PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.32517973
57PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.30930999
58KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.30220845
59E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.30172313
60TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.30150752
61SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.29943853
62VDR_24787735_ChIP-Seq_THP-1_Human1.29057689
63LXR_22292898_ChIP-Seq_THP-1_Human1.28334820
64TRIM28_21343339_ChIP-Seq_HEK293_Human1.28216266
65IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.28010682
66MYB_26560356_Chip-Seq_TH1_Human1.27718143
67MYB_26560356_Chip-Seq_TH2_Human1.27660718
68MYC_18555785_ChIP-Seq_MESCs_Mouse1.27167020
69* ATF3_27146783_Chip-Seq_COLON_Human1.26197126
70* UBF1/2_26484160_Chip-Seq_HMECs_Human1.25880398
71TP53_22127205_ChIP-Seq_IMR90_Human1.25115004
72ZNF263_19887448_ChIP-Seq_K562_Human1.23875391
73JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.22000600
74MYC_19079543_ChIP-ChIP_MESCs_Mouse1.21397810
75* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.20412550
76* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.20412550
77STAT4_19710469_ChIP-ChIP_TH1__Mouse1.19999354
78GATA1_22383799_ChIP-Seq_G1ME_Mouse1.19836299
79PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.19651681
80* KDM2B_26808549_Chip-Seq_K562_Human1.18197184
81KDM2B_26808549_Chip-Seq_SUP-B15_Human1.17536349
82SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.17434662
83KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.16878830
84TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.16144968
85CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.15962860
86RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.15573771
87CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14008481
88MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.13424574
89GATA2_22383799_ChIP-Seq_G1ME_Mouse1.13151000
90* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.12073113
91GATA1_19941827_ChIP-Seq_MEL_Mouse1.11811013
92AR_21909140_ChIP-Seq_LNCAP_Human1.11731868
93IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.10637656
94TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.10049917
95POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.09045509
96* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.08920339
97PU_27001747_Chip-Seq_BMDM_Mouse1.08284786
98PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.08074756
99SMAD_19615063_ChIP-ChIP_OVARY_Human1.07601285
100ESR1_21235772_ChIP-Seq_MCF-7_Human1.07513214
101RXR_22158963_ChIP-Seq_LIVER_Mouse1.06500665
102* NCOR1_26117541_ChIP-Seq_K562_Human1.06114557
103KDM2B_26808549_Chip-Seq_DND41_Human1.05832841
104STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.05800271
105JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.05702620
106P63_26484246_Chip-Seq_KERATINOCYTES_Human1.05375276
107CTCF_27219007_Chip-Seq_ERYTHROID_Human1.04588621
108SMC1_22415368_ChIP-Seq_MEFs_Mouse1.04072825
109ESR1_15608294_ChIP-ChIP_MCF-7_Human1.03459022
110CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.03136144
111GATA2_21666600_ChIP-Seq_HMVEC_Human1.02293235
112TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02079079
113STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.01765484
114* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00799044
115* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.00745586
116KLF4_18555785_ChIP-Seq_MESCs_Mouse1.00701669
117ELF1_17652178_ChIP-ChIP_JURKAT_Human1.00491789
118PPARA_22158963_ChIP-Seq_LIVER_Mouse0.99862545
119* GATA1_19941826_ChIP-Seq_K562_Human0.99798549
120LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.98937296
121E2F4_17652178_ChIP-ChIP_JURKAT_Human0.98907916
122NANOG_18555785_ChIP-Seq_MESCs_Mouse0.98163893
123TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.97768427
124KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.96586028
125NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.96549942
126* SOX2_20726797_ChIP-Seq_SW620_Human0.95970586
127GATA6_25053715_ChIP-Seq_YYC3_Human0.95700340
128KDM2B_26808549_Chip-Seq_JURKAT_Human0.95510276
129SA1_27219007_Chip-Seq_ERYTHROID_Human0.95339963
130SRY_22984422_ChIP-ChIP_TESTIS_Rat0.94810693
131* MYC_18358816_ChIP-ChIP_MESCs_Mouse0.94691044
132ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.94308782
133HIF1A_21447827_ChIP-Seq_MCF-7_Human0.93668438
134ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93488212
135HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.93230513
136BCL6_27268052_Chip-Seq_Bcells_Human0.91396724
137DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.90497033
138SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.89515502

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003566_abnormal_cell_adhesion2.79393282
2MP0003436_decreased_susceptibility_to2.77919943
3MP0003303_peritoneal_inflammation2.68252696
4MP0005058_abnormal_lysosome_morphology2.60926126
5MP0010352_gastrointestinal_tract_polyps2.55801051
6MP0003705_abnormal_hypodermis_morpholog2.52810136
7MP0009278_abnormal_bone_marrow2.38485833
8MP0005451_abnormal_body_composition2.30363083
9MP0002419_abnormal_innate_immunity2.18014692
10MP0003300_gastrointestinal_ulcer2.08298590
11MP0000465_gastrointestinal_hemorrhage2.07681066
12MP0008260_abnormal_autophagy2.06140354
13MP0005397_hematopoietic_system_phenotyp2.04502140
14MP0001545_abnormal_hematopoietic_system2.04502140
15MP0005464_abnormal_platelet_physiology2.02019286
16MP0003172_abnormal_lysosome_physiology1.97920544
17MP0003693_abnormal_embryo_hatching1.96105904
18MP0000490_abnormal_crypts_of1.95937300
19MP0000604_amyloidosis1.95636342
20MP0005023_abnormal_wound_healing1.89902884
21MP0009785_altered_susceptibility_to1.89588095
22MP0000858_altered_metastatic_potential1.86130450
23MP0002396_abnormal_hematopoietic_system1.83838892
24MP0005025_abnormal_response_to1.74112259
25MP0003950_abnormal_plasma_membrane1.73930321
26MP0010307_abnormal_tumor_latency1.73255856
27MP0005076_abnormal_cell_differentiation1.71993926
28MP0004947_skin_inflammation1.68236065
29MP0003191_abnormal_cellular_cholesterol1.67576533
30MP0000343_altered_response_to1.67396818
31MP0009840_abnormal_foam_cell1.66218423
32MP0001835_abnormal_antigen_presentation1.62949355
33MP0010155_abnormal_intestine_physiology1.61813479
34MP0000569_abnormal_digit_pigmentation1.58854907
35MP0001533_abnormal_skeleton_physiology1.58405179
36MP0003724_increased_susceptibility_to1.56574506
37MP0004808_abnormal_hematopoietic_stem1.56421296
38MP0010234_abnormal_vibrissa_follicle1.55142286
39MP0002452_abnormal_antigen_presenting1.54752853
40MP0008438_abnormal_cutaneous_collagen1.54149542
41MP0003448_altered_tumor_morphology1.53895679
42MP0001958_emphysema1.49007615
43MP0001542_abnormal_bone_strength1.48328952
44MP0003806_abnormal_nucleotide_metabolis1.46468153
45MP0005000_abnormal_immune_tolerance1.46411403
46MP0002405_respiratory_system_inflammati1.46229704
47MP0002060_abnormal_skin_morphology1.45227159
48MP0005174_abnormal_tail_pigmentation1.44616389
49MP0003111_abnormal_nucleus_morphology1.43497351
50MP0001819_abnormal_immune_cell1.40800921
51MP0003329_amyloid_beta_deposits1.40089390
52MP0002420_abnormal_adaptive_immunity1.39548727
53MP0000685_abnormal_immune_system1.38056909
54MP0002148_abnormal_hypersensitivity_rea1.34264533
55MP0003453_abnormal_keratinocyte_physiol1.32962944
56MP0002877_abnormal_melanocyte_morpholog1.32817658
57MP0005387_immune_system_phenotype1.28726930
58MP0001790_abnormal_immune_system1.28726930
59MP0001845_abnormal_inflammatory_respons1.26687834
60MP0004272_abnormal_basement_membrane1.25647533
61MP0002723_abnormal_immune_serum1.25128405
62MP0001853_heart_inflammation1.24529314
63MP0001800_abnormal_humoral_immune1.22943552
64MP0006054_spinal_hemorrhage1.22936571
65MP0003091_abnormal_cell_migration1.20650748
66MP0003183_abnormal_peptide_metabolism1.19778994
67MP0001851_eye_inflammation1.18983025
68MP0004957_abnormal_blastocyst_morpholog1.17708091
69MP0005257_abnormal_intraocular_pressure1.17418328
70MP0003866_abnormal_defecation1.16911045
71MP0001873_stomach_inflammation1.16543426
72MP0001849_ear_inflammation1.13674241
73MP0002398_abnormal_bone_marrow1.13376688
74MP0009764_decreased_sensitivity_to1.08596278
75MP0000716_abnormal_immune_system1.07370807
76MP0004264_abnormal_extraembryonic_tissu1.05753909
77MP0001216_abnormal_epidermal_layer1.05142195
78MP0000689_abnormal_spleen_morphology1.04895650
79MP0004883_abnormal_blood_vessel1.04730327
80MP0002722_abnormal_immune_system1.03761404
81MP0004510_myositis1.03556711
82MP0009333_abnormal_splenocyte_physiolog1.02785527
83MP0003075_altered_response_to1.01974096
84MP0002429_abnormal_blood_cell1.01872310
85MP0004185_abnormal_adipocyte_glucose1.00617273
86MP0000767_abnormal_smooth_muscle0.98329615
87MP0003077_abnormal_cell_cycle0.97090121
88MP0002896_abnormal_bone_mineralization0.96687710
89MP0000579_abnormal_nail_morphology0.95876877
90MP0005166_decreased_susceptibility_to0.95002652
91MP0005165_increased_susceptibility_to0.94676037
92MP0003828_pulmonary_edema0.94588318
93MP0006082_CNS_inflammation0.93850249
94MP0003279_aneurysm0.93612122
95MP0002019_abnormal_tumor_incidence0.92336463
96MP0000477_abnormal_intestine_morphology0.92315162
97MP0005275_abnormal_skin_tensile0.92156819
98MP0000371_diluted_coat_color0.91279566
99MP0005501_abnormal_skin_physiology0.91259601
100MP0008004_abnormal_stomach_pH0.90698065
101MP0004858_abnormal_nervous_system0.89436152
102MP0005390_skeleton_phenotype0.87246134
103MP0003690_abnormal_glial_cell0.87113812
104MP0002796_impaired_skin_barrier0.86078260
105MP0002254_reproductive_system_inflammat0.85767921
106MP0005310_abnormal_salivary_gland0.85623119
107MP0005671_abnormal_response_to0.85258251
108MP0001243_abnormal_dermal_layer0.84314476
109MP0008469_abnormal_protein_level0.83926992
110MP0005621_abnormal_cell_physiology0.83871241
111MP0002166_altered_tumor_susceptibility0.83356814
112MP0009053_abnormal_anal_canal0.80727850
113MP0004782_abnormal_surfactant_physiolog0.80024141
114MP0009931_abnormal_skin_appearance0.79413835
115MP0003941_abnormal_skin_development0.79237079
116MP0005164_abnormal_response_to0.79158015
117MP0005595_abnormal_vascular_smooth0.78112441
118MP0003656_abnormal_erythrocyte_physiolo0.77947977
119MP0008007_abnormal_cellular_replicative0.77015949
120MP0001663_abnormal_digestive_system0.76807960
121MP0000350_abnormal_cell_proliferation0.74849061
122MP0000920_abnormal_myelination0.74264942
123MP0000249_abnormal_blood_vessel0.74149866
124MP0000467_abnormal_esophagus_morphology0.73819533
125MP0005409_darkened_coat_color0.73432483
126MP0002998_abnormal_bone_remodeling0.72560734
127MP0001191_abnormal_skin_condition0.72020920
128MP0005167_abnormal_blood-brain_barrier0.70647157
129MP0005623_abnormal_meninges_morphology0.70290824
130MP0003795_abnormal_bone_structure0.69422377

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.20529236
2Eczematoid dermatitis (HP:0000976)5.11778793
3Recurrent bacterial skin infections (HP:0005406)4.59210423
4Abnormality of macrophages (HP:0004311)3.76581963
5Recurrent gram-negative bacterial infections (HP:0005420)3.74524919
6Vacuolated lymphocytes (HP:0001922)3.71962108
7Increased cerebral lipofuscin (HP:0011813)3.60125661
8Myositis (HP:0100614)3.52188856
9Interstitial pulmonary disease (HP:0006530)3.34307849
10Increased neuronal autofluorescent lipopigment (HP:0002074)3.13209047
11Thrombocytosis (HP:0001894)3.05578563
12Obstructive lung disease (HP:0006536)3.02373725
13Chronic obstructive pulmonary disease (HP:0006510)3.02373725
14Pustule (HP:0200039)3.00972898
15Neurofibrillary tangles (HP:0002185)2.99924622
16Dysostosis multiplex (HP:0000943)2.93973484
17Myocardial infarction (HP:0001658)2.91841024
18Milia (HP:0001056)2.87664593
19Gingivitis (HP:0000230)2.85829557
20Cellulitis (HP:0100658)2.85756826
21Periodontitis (HP:0000704)2.85243829
22Atrophic scars (HP:0001075)2.84226265
23Thick nail (HP:0001805)2.81117193
24Orchitis (HP:0100796)2.78656210
25Recurrent fungal infections (HP:0002841)2.74066574
26Elevated erythrocyte sedimentation rate (HP:0003565)2.73560090
27Mucopolysacchariduria (HP:0008155)2.71575191
28Urinary glycosaminoglycan excretion (HP:0003541)2.71575191
29Cervical subluxation (HP:0003308)2.70578812
30Abnormality of the nasal mucosa (HP:0000433)2.68744263
31Cerebral aneurysm (HP:0004944)2.67478983
32Chronic otitis media (HP:0000389)2.57365728
33Abnormality of mucopolysaccharide metabolism (HP:0011020)2.55155199
34Abnormality of polysaccharide metabolism (HP:0011012)2.55155199
35Abnormality of glycosaminoglycan metabolism (HP:0004371)2.55155199
36Systemic lupus erythematosus (HP:0002725)2.54571286
37Mediastinal lymphadenopathy (HP:0100721)2.52752320
38Premature rupture of membranes (HP:0001788)2.49648752
39Protrusio acetabuli (HP:0003179)2.49411752
40Spondylolisthesis (HP:0003302)2.43795318
41Impaired platelet aggregation (HP:0003540)2.43452754
42Abnormal platelet function (HP:0011869)2.43452754
43Recurrent skin infections (HP:0001581)2.43389225
44Nasal polyposis (HP:0100582)2.41518081
45Cerebral inclusion bodies (HP:0100314)2.40772973
46Hand muscle atrophy (HP:0009130)2.36586071
47Ulnar bowing (HP:0003031)2.36046805
48Peritonitis (HP:0002586)2.34110670
49Nuclear cataract (HP:0100018)2.31773276
50Natal tooth (HP:0000695)2.31335215
51Poikiloderma (HP:0001029)2.26758364
52Upper motor neuron abnormality (HP:0002127)2.26732016
53Short nail (HP:0001799)2.26601702
54Distal upper limb amyotrophy (HP:0007149)2.23701413
55Upper limb amyotrophy (HP:0009129)2.23701413
56Spontaneous hematomas (HP:0007420)2.23564927
57Autoimmune thrombocytopenia (HP:0001973)2.20617274
58Osteolytic defects of the hand bones (HP:0009699)2.20535491
59Osteolytic defects of the phalanges of the hand (HP:0009771)2.20535491
60Right ventricular cardiomyopathy (HP:0011663)2.18917012
61Amyloidosis (HP:0011034)2.17378442
62Disinhibition (HP:0000734)2.16306032
63Petechiae (HP:0000967)2.15938519
64Loss of speech (HP:0002371)2.15246048
65Urticaria (HP:0001025)2.14671907
66Nail dystrophy (HP:0008404)2.13624461
67Cheilitis (HP:0100825)2.12586706
68Ureteral stenosis (HP:0000071)2.12162176
69Broad face (HP:0000283)2.12150032
70Radial bowing (HP:0002986)2.11925384
71Increased connective tissue (HP:0009025)2.11447353
72Neuronal loss in central nervous system (HP:0002529)2.10592709
73Agnosia (HP:0010524)2.08319627
74Purpura (HP:0000979)2.05984425
75Alopecia of scalp (HP:0002293)2.05931267
76Apathy (HP:0000741)2.05664155
77Malnutrition (HP:0004395)2.04106843
78Diminished motivation (HP:0000745)2.03944460
79Abnormal platelet volume (HP:0011876)2.03787144
80Entropion (HP:0000621)2.03567854
81Achilles tendon contracture (HP:0001771)2.01991362
82Supranuclear gaze palsy (HP:0000605)2.00576076
83Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.98466634
84Albinism (HP:0001022)1.97825111
85Skin ulcer (HP:0200042)1.97613467
86Hepatosplenomegaly (HP:0001433)1.96684047
87Pili torti (HP:0003777)1.96416290
88Abnormality of nail color (HP:0100643)1.96348132
89Epistaxis (HP:0000421)1.95985851
90Increased serum ferritin (HP:0003281)1.95946889
91Hematochezia (HP:0002573)1.95851430
92Ureteral obstruction (HP:0006000)1.95003435
93Asymmetric septal hypertrophy (HP:0001670)1.94202826
94Vertebral compression fractures (HP:0002953)1.92161360
95Fragile skin (HP:0001030)1.92023478
96Osteomyelitis (HP:0002754)1.91029892
97Dilatation of the ascending aorta (HP:0005111)1.90500868
98Mitral stenosis (HP:0001718)1.90243720
99Selective tooth agenesis (HP:0001592)1.89968082
100Recurrent viral infections (HP:0004429)1.89452934
101Distal lower limb amyotrophy (HP:0008944)1.89137538
102Prolonged bleeding time (HP:0003010)1.88951837
103Increased mean platelet volume (HP:0011877)1.88160106
104Progressive neurologic deterioration (HP:0002344)1.86764397
105Joint stiffness (HP:0001387)1.86385754
106IgM deficiency (HP:0002850)1.86205214
107Aortic aneurysm (HP:0004942)1.86189143
108Aortic dissection (HP:0002647)1.85506646
109Increased density of long bones (HP:0006392)1.85478890
110Plantar hyperkeratosis (HP:0007556)1.84375500
111Bone pain (HP:0002653)1.84082142
112Thin bony cortex (HP:0002753)1.83488753
113Onycholysis (HP:0001806)1.83432808
114Abnormal blistering of the skin (HP:0008066)1.82283601
115Vascular tortuosity (HP:0004948)1.82244611
116Prolonged neonatal jaundice (HP:0006579)1.82241664
117Increased IgE level (HP:0003212)1.81394416
118Bowing of the arm (HP:0006488)1.78946077
119Bowed forearm bones (HP:0003956)1.78946077
120Arterial tortuosity (HP:0005116)1.78862762
121Abnormality of the Achilles tendon (HP:0005109)1.77391112
122Wormian bones (HP:0002645)1.77261712
123Gastrointestinal dysmotility (HP:0002579)1.76703767
124Ankle contracture (HP:0006466)1.76686178
125Distal lower limb muscle weakness (HP:0009053)1.75922896
126Axonal loss (HP:0003447)1.75139498
127Shallow orbits (HP:0000586)1.74671896
128Abnormality of glycolipid metabolism (HP:0010969)1.74591494
129Abnormality of liposaccharide metabolism (HP:0010968)1.74591494
130Abnormality of glycosphingolipid metabolism (HP:0004343)1.74591494
131Chest pain (HP:0100749)1.74504981
132Abnormality of the distal phalanges of the toes (HP:0010182)1.72637583
133Premature loss of primary teeth (HP:0006323)1.72312996
134Inflammation of the large intestine (HP:0002037)1.71938063
135Gastrointestinal inflammation (HP:0004386)1.70585852
136Menorrhagia (HP:0000132)1.70082587
137Fragile nails (HP:0001808)1.69177261
138Arterial thrombosis (HP:0004420)1.68956139
139Frequent falls (HP:0002359)1.68691411
140Spinal rigidity (HP:0003306)1.68351701
141Mutism (HP:0002300)1.68263913
142Polygenic inheritance (HP:0010982)1.67020239
143Elbow flexion contracture (HP:0002987)1.66926665
144Pathologic fracture (HP:0002756)1.66718599
145Genu recurvatum (HP:0002816)1.65238468

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN13.48303757
2EPHA23.32268955
3TRIB33.16971318
4PIM22.60748228
5PRPF4B2.38219677
6PKN22.35999689
7TTN2.26025655
8STK102.24032543
9EEF2K2.14829229
10TAOK22.10258378
11PAK42.10203882
12IRAK41.99874612
13RIPK11.94360332
14TESK11.92037183
15EPHB11.90399301
16MAP4K11.84143869
17SIK11.82430252
18CDK121.78773590
19LRRK21.74684874
20KIT1.73703332
21TRPM71.69758857
22RPS6KB21.66849531
23TBK11.63382788
24PTK61.61271119
25NEK21.59429732
26BTK1.55808322
27GRK71.54937841
28PDGFRA1.53956509
29BLK1.53625141
30TESK21.47703555
31MAP3K31.44501006
32RIPK41.44311801
33TGFBR21.41331348
34MAP2K31.39279035
35MOS1.34341216
36IRAK31.32073840
37PRKD21.31749303
38ARAF1.29474986
39MAPKAPK31.29467690
40EPHB21.27704865
41PRKG21.25462985
42RPS6KA41.25332728
43PTK21.24850324
44MET1.24568542
45MAP3K111.24499097
46PIM11.22247329
47SCYL21.21799416
48CSK1.18456660
49CDC42BPA1.17461825
50SMG11.17071140
51MAP3K61.14871954
52FLT31.11262476
53MAP3K11.10757210
54KDR1.09612998
55LIMK11.09131744
56ZAP701.06074542
57CAMK1D1.05910205
58NEK91.04959240
59WEE11.03235019
60MAP3K81.02868831
61TEC1.01753520
62JAK31.01398044
63HCK1.01321871
64CDK60.98197961
65ICK0.98168017
66KSR20.96912656
67NME20.96138483
68TAOK10.96122501
69MATK0.92044184
70GRK60.91792615
71BMX0.87438027
72CDK70.87214672
73STK380.86347412
74TYK20.85812797
75MAP3K140.82800719
76PDPK10.82757425
77IKBKB0.78145572
78TAOK30.77868916
79NTRK10.75223002
80PAK20.75036026
81MARK30.73935156
82JAK10.72095144
83MAP3K20.70406329
84LATS20.69598405
85RPS6KA60.68232384
86FES0.67716237
87FGR0.67560052
88PDGFRB0.67061801
89PAK10.66006555
90RPS6KC10.65179282
91RPS6KL10.65179282
92MST1R0.63638105
93BRSK20.63003945
94AURKB0.62411148
95MAP3K50.60426335
96MAPKAPK20.60008649
97PTK2B0.59830803
98CSF1R0.59446114
99IRAK20.58347687
100MAP2K20.57679027
101MTOR0.57664029
102SIK30.57254515
103PIK3CG0.56417481
104MARK20.55887409
105STK40.55506216
106DAPK30.54302498
107CDK40.53760421
108ILK0.51618139
109CHUK0.51262646
110MYLK0.49360976
111TGFBR10.49143568
112MAP3K100.48731476
113MAP3K130.48658206
114STK240.48507539
115TTK0.48244822
116STK30.47833133
117ERBB40.47378809
118SIK20.47131046
119IKBKE0.46854377
120MST40.45672287
121PRKCI0.45411744
122ABL10.44554296
123SYK0.44086033
124LMTK20.43880496
125RPS6KA20.42638455
126DDR20.42496463
127ABL20.42490554
128RAF10.42451699
129ALK0.42128841
130LCK0.41848698
131ITK0.41061247
132MAPK70.39690104
133GSK3A0.36435054
134ROCK20.35583008
135DYRK1B0.34587601

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051402.47842268
2Glycosaminoglycan degradation_Homo sapiens_hsa005312.47109301
3Other glycan degradation_Homo sapiens_hsa005112.36054863
4Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.23911902
5Lysosome_Homo sapiens_hsa041422.03436314
6Shigellosis_Homo sapiens_hsa051311.96162467
7Leukocyte transendothelial migration_Homo sapiens_hsa046701.88676986
8Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.76506815
9Osteoclast differentiation_Homo sapiens_hsa043801.70445800
10Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.68677505
11Apoptosis_Homo sapiens_hsa042101.65815339
12Tuberculosis_Homo sapiens_hsa051521.58088806
13Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.58087646
14Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.57608111
15Legionellosis_Homo sapiens_hsa051341.55569083
16Chronic myeloid leukemia_Homo sapiens_hsa052201.54940325
17p53 signaling pathway_Homo sapiens_hsa041151.54828670
18Pentose phosphate pathway_Homo sapiens_hsa000301.53286937
19Bladder cancer_Homo sapiens_hsa052191.53262699
20Small cell lung cancer_Homo sapiens_hsa052221.51467787
21Acute myeloid leukemia_Homo sapiens_hsa052211.47917005
22Phagosome_Homo sapiens_hsa041451.46917024
23Toxoplasmosis_Homo sapiens_hsa051451.44856242
24Malaria_Homo sapiens_hsa051441.43911993
25Caffeine metabolism_Homo sapiens_hsa002321.33343195
26Antigen processing and presentation_Homo sapiens_hsa046121.32355224
27B cell receptor signaling pathway_Homo sapiens_hsa046621.31306755
28NF-kappa B signaling pathway_Homo sapiens_hsa040641.30785703
29Salmonella infection_Homo sapiens_hsa051321.30341552
30Toll-like receptor signaling pathway_Homo sapiens_hsa046201.29307775
31DNA replication_Homo sapiens_hsa030301.27949072
32Base excision repair_Homo sapiens_hsa034101.26307125
33Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.24654065
34Pertussis_Homo sapiens_hsa051331.24085969
35TNF signaling pathway_Homo sapiens_hsa046681.21715015
36Hematopoietic cell lineage_Homo sapiens_hsa046401.20216205
37Amoebiasis_Homo sapiens_hsa051461.14007288
38Influenza A_Homo sapiens_hsa051641.13646249
39AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.12416407
40Hepatitis B_Homo sapiens_hsa051611.10907204
41Vibrio cholerae infection_Homo sapiens_hsa051101.10824387
42NOD-like receptor signaling pathway_Homo sapiens_hsa046211.09706798
43Proteoglycans in cancer_Homo sapiens_hsa052051.09424289
44Pancreatic cancer_Homo sapiens_hsa052121.08982252
45Prion diseases_Homo sapiens_hsa050201.07673875
46Measles_Homo sapiens_hsa051621.07385269
47Renin-angiotensin system_Homo sapiens_hsa046141.06355142
48RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.05338148
49Staphylococcus aureus infection_Homo sapiens_hsa051501.05156720
50Platelet activation_Homo sapiens_hsa046111.04304939
51Focal adhesion_Homo sapiens_hsa045101.04277247
52Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.03586412
53Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.01314454
54Sphingolipid metabolism_Homo sapiens_hsa006001.00679305
55Regulation of actin cytoskeleton_Homo sapiens_hsa048100.97151742
56Transcriptional misregulation in cancer_Homo sapiens_hsa052020.94339849
57Allograft rejection_Homo sapiens_hsa053300.93866925
58VEGF signaling pathway_Homo sapiens_hsa043700.91399364
59HIF-1 signaling pathway_Homo sapiens_hsa040660.90667804
60ECM-receptor interaction_Homo sapiens_hsa045120.90379290
61Graft-versus-host disease_Homo sapiens_hsa053320.90299117
62MicroRNAs in cancer_Homo sapiens_hsa052060.89653534
63Viral carcinogenesis_Homo sapiens_hsa052030.89461991
64Herpes simplex infection_Homo sapiens_hsa051680.89317242
65Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.87436644
66Galactose metabolism_Homo sapiens_hsa000520.87372611
67Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.87186708
68Fructose and mannose metabolism_Homo sapiens_hsa000510.85338195
69Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.84268561
70Complement and coagulation cascades_Homo sapiens_hsa046100.84018843
71Jak-STAT signaling pathway_Homo sapiens_hsa046300.83053473
72Cell cycle_Homo sapiens_hsa041100.81970961
73Autoimmune thyroid disease_Homo sapiens_hsa053200.80692847
74Adherens junction_Homo sapiens_hsa045200.80384115
75Renal cell carcinoma_Homo sapiens_hsa052110.79318309
76Hepatitis C_Homo sapiens_hsa051600.78957762
77Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.76811075
78Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.75655185
79Epstein-Barr virus infection_Homo sapiens_hsa051690.75615904
80Thyroid cancer_Homo sapiens_hsa052160.75583572
81Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.75536923
82HTLV-I infection_Homo sapiens_hsa051660.72490226
83Neurotrophin signaling pathway_Homo sapiens_hsa047220.71854343
84Ribosome_Homo sapiens_hsa030100.69538449
85Central carbon metabolism in cancer_Homo sapiens_hsa052300.68281044
86Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.67581475
87Collecting duct acid secretion_Homo sapiens_hsa049660.65327021
88Non-small cell lung cancer_Homo sapiens_hsa052230.65074462
89Chemokine signaling pathway_Homo sapiens_hsa040620.64985446
90GnRH signaling pathway_Homo sapiens_hsa049120.64542949
91Rheumatoid arthritis_Homo sapiens_hsa053230.63674947
92Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.60948063
93Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.60493173
94Phospholipase D signaling pathway_Homo sapiens_hsa040720.59521287
95Viral myocarditis_Homo sapiens_hsa054160.58633179
96Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.56500761
97mTOR signaling pathway_Homo sapiens_hsa041500.56177985
98Notch signaling pathway_Homo sapiens_hsa043300.55661421
99Endocytosis_Homo sapiens_hsa041440.55232265
100Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.54307110
101Glutathione metabolism_Homo sapiens_hsa004800.54154949
102Pathways in cancer_Homo sapiens_hsa052000.53423604
103Mineral absorption_Homo sapiens_hsa049780.52966940
104Mismatch repair_Homo sapiens_hsa034300.51214310
105Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.50873662
106African trypanosomiasis_Homo sapiens_hsa051430.50852024
107Adipocytokine signaling pathway_Homo sapiens_hsa049200.50567422
108N-Glycan biosynthesis_Homo sapiens_hsa005100.50563414
109RNA transport_Homo sapiens_hsa030130.50492096
110Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.50236662
111Endometrial cancer_Homo sapiens_hsa052130.50100910
112Prolactin signaling pathway_Homo sapiens_hsa049170.49827721
113Homologous recombination_Homo sapiens_hsa034400.48080319
114Carbohydrate digestion and absorption_Homo sapiens_hsa049730.47380523
115Insulin resistance_Homo sapiens_hsa049310.46256506
116SNARE interactions in vesicular transport_Homo sapiens_hsa041300.45371629
117Sphingolipid signaling pathway_Homo sapiens_hsa040710.44726606
118Asthma_Homo sapiens_hsa053100.44080856
119Intestinal immune network for IgA production_Homo sapiens_hsa046720.43907579
120Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.43199582
121T cell receptor signaling pathway_Homo sapiens_hsa046600.41580218
122Sulfur metabolism_Homo sapiens_hsa009200.41527613
123ErbB signaling pathway_Homo sapiens_hsa040120.41503091
124Rap1 signaling pathway_Homo sapiens_hsa040150.39810869

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