TBC1D2B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.18848275
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.18848275
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.98257560
4negative regulation of cell killing (GO:0031342)3.98257560
5negative regulation of erythrocyte differentiation (GO:0045647)3.74368866
6antigen processing and presentation of endogenous antigen (GO:0019883)3.55489928
7protein carboxylation (GO:0018214)3.55112441
8peptidyl-glutamic acid carboxylation (GO:0017187)3.55112441
9detection of other organism (GO:0098543)3.42717735
10apoptotic cell clearance (GO:0043277)3.39099276
11antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.34624286
12positive regulation by symbiont of host defense response (GO:0052509)3.29060652
13modulation by symbiont of host defense response (GO:0052031)3.29060652
14modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.29060652
15modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.29060652
16positive regulation by organism of defense response of other organism involved in symbiotic interact3.29060652
17modulation by symbiont of host immune response (GO:0052553)3.29060652
18detection of bacterium (GO:0016045)3.26930295
19regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 3.14015751
20complement activation, alternative pathway (GO:0006957)3.05415497
21negative regulation of phagocytosis (GO:0050765)3.03086561
22regulation of interferon-beta biosynthetic process (GO:0045357)3.00301158
23mannose metabolic process (GO:0006013)2.99067577
24positive regulation of gamma-delta T cell activation (GO:0046645)2.97641515
25positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.96819782
26macrophage activation involved in immune response (GO:0002281)2.93279061
27regulation of dendritic cell antigen processing and presentation (GO:0002604)2.85693162
28endodermal cell differentiation (GO:0035987)2.80971107
29regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.79979229
30barbed-end actin filament capping (GO:0051016)2.79743337
31cell adhesion mediated by integrin (GO:0033627)2.79040134
32pinocytosis (GO:0006907)2.78062738
33germinal center formation (GO:0002467)2.77956254
34low-density lipoprotein particle clearance (GO:0034383)2.76610500
35detection of biotic stimulus (GO:0009595)2.75856799
36response to laminar fluid shear stress (GO:0034616)2.75713877
37regulation of protein activation cascade (GO:2000257)2.71901774
38regulation of complement activation (GO:0030449)2.70051009
39cellular extravasation (GO:0045123)2.69809213
40detection of molecule of bacterial origin (GO:0032490)2.68674971
41negative thymic T cell selection (GO:0045060)2.68418414
42triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.66680903
43protein localization to endosome (GO:0036010)2.66182867
44regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.65378567
45positive regulation of fatty acid beta-oxidation (GO:0032000)2.63875058
46positive regulation of p38MAPK cascade (GO:1900745)2.63136438
47positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.62025274
48regulation of T cell tolerance induction (GO:0002664)2.61075787
49regulation of apoptotic cell clearance (GO:2000425)2.58936993
50regulation of extracellular matrix disassembly (GO:0010715)2.58496971
51regulation of cholesterol storage (GO:0010885)2.57368062
52killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.56520389
53disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.56520389
54response to muramyl dipeptide (GO:0032495)2.56481031
55negative T cell selection (GO:0043383)2.53207735
56regulation of tolerance induction (GO:0002643)2.52459354
57regulation of B cell receptor signaling pathway (GO:0050855)2.52191825
58negative regulation of granulocyte differentiation (GO:0030853)2.52112653
59positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.51625109
60hypotonic response (GO:0006971)2.51466277
61response to fluid shear stress (GO:0034405)2.50832811
62regulation of leukocyte degranulation (GO:0043300)2.50400573
63positive regulation of sterol transport (GO:0032373)2.48450757
64positive regulation of cholesterol transport (GO:0032376)2.48450757
65regulation of myeloid leukocyte mediated immunity (GO:0002886)2.48270507
66response to type I interferon (GO:0034340)2.48162604
67growth hormone receptor signaling pathway (GO:0060396)2.48021970
68immunoglobulin mediated immune response (GO:0016064)2.47784997
69basement membrane organization (GO:0071711)2.47692717
70positive regulation of natural killer cell differentiation (GO:0032825)2.46560442
71positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.46068762
72regulation of T-helper 2 cell differentiation (GO:0045628)2.45597618
73type I interferon signaling pathway (GO:0060337)2.45321075
74cellular response to type I interferon (GO:0071357)2.45321075
75phospholipid efflux (GO:0033700)2.45319705
76regulation of macrophage cytokine production (GO:0010935)2.45030939
77plasma lipoprotein particle clearance (GO:0034381)2.43935756
78positive regulation of cholesterol efflux (GO:0010875)2.43788140
79B cell receptor signaling pathway (GO:0050853)2.43344607
80lipopolysaccharide-mediated signaling pathway (GO:0031663)2.42630793
81positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.42363878
82regulation of interleukin-12 biosynthetic process (GO:0045075)2.41901345
83protein heterotrimerization (GO:0070208)2.41602237
84phospholipid homeostasis (GO:0055091)2.40832726
85negative regulation of fibrinolysis (GO:0051918)2.40554199
86positive regulation of Cdc42 GTPase activity (GO:0043089)2.40269440
87stress fiber assembly (GO:0043149)2.39502163
88neutrophil mediated immunity (GO:0002446)2.39281461
89neutrophil activation involved in immune response (GO:0002283)2.38789612
90positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.38227703
91thymic T cell selection (GO:0045061)2.37850598
92negative regulation of lymphocyte mediated immunity (GO:0002707)2.37661966
93regulation of mast cell degranulation (GO:0043304)2.37429104
94positive regulation of B cell differentiation (GO:0045579)2.37302489
95defense response to fungus (GO:0050832)2.37223698
96negative regulation of interleukin-12 production (GO:0032695)2.36850500
97response to peptidoglycan (GO:0032494)2.36810732
98positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.36342491
99response to interleukin-15 (GO:0070672)2.35522947
100regulation of fatty acid beta-oxidation (GO:0031998)2.35519756
101negative regulation of stress fiber assembly (GO:0051497)2.35501564
102T cell selection (GO:0045058)2.35414971
103negative regulation of leukocyte mediated immunity (GO:0002704)2.35342886
104germ cell migration (GO:0008354)2.35239119
105regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.35178279
106positive regulation of histone deacetylation (GO:0031065)2.34774100
107regulation of gamma-delta T cell differentiation (GO:0045586)2.33028579
108regulation of gamma-delta T cell activation (GO:0046643)2.32618246
109positive regulation of receptor recycling (GO:0001921)2.32553094
110response to fungus (GO:0009620)2.32486149
111regulation of phagocytosis (GO:0050764)2.31464498
112leukocyte aggregation (GO:0070486)2.31157051
113positive regulation of tolerance induction (GO:0002645)2.30795243
114regulation of necroptotic process (GO:0060544)2.30258381
115positive regulation of cellular amide metabolic process (GO:0034250)2.29643541
116alpha-linolenic acid metabolic process (GO:0036109)2.28706021
117vascular endothelial growth factor signaling pathway (GO:0038084)2.28619053
118regulation of type I interferon-mediated signaling pathway (GO:0060338)2.28597295
119antigen processing and presentation via MHC class Ib (GO:0002475)2.28595229
120positive regulation of blood coagulation (GO:0030194)2.28480909
121positive regulation of hemostasis (GO:1900048)2.28480909
122positive regulation of extracellular matrix organization (GO:1903055)2.28232287
123interferon-gamma-mediated signaling pathway (GO:0060333)2.27160464
124skin morphogenesis (GO:0043589)2.26505411
125positive regulation of interferon-alpha production (GO:0032727)2.26378068
126negative regulation of T cell mediated immunity (GO:0002710)2.25838718
127positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.25693945
128urea cycle (GO:0000050)2.24937496
129urea metabolic process (GO:0019627)2.24937496
130regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.23472794
131response to interferon-alpha (GO:0035455)2.23413015
132negative regulation of fatty acid transport (GO:2000192)2.22780109
133collagen metabolic process (GO:0032963)2.22338128
134negative regulation of innate immune response (GO:0045824)2.22106083
135positive thymic T cell selection (GO:0045059)2.22062509
136NIK/NF-kappaB signaling (GO:0038061)2.21333804
137positive regulation of lipid catabolic process (GO:0050996)2.21324002
138blood vessel maturation (GO:0001955)2.21210411
139response to host (GO:0075136)2.20954186
140response to host defenses (GO:0052200)2.20954186
141response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.20954186
142macrophage activation (GO:0042116)2.20736632
143myeloid dendritic cell differentiation (GO:0043011)2.20323755
144adhesion of symbiont to host cell (GO:0044650)2.20149621
145virion attachment to host cell (GO:0019062)2.20149621
146JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.19884360
147positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.19853592
148regulation of fibrinolysis (GO:0051917)2.19548155
149embryonic process involved in female pregnancy (GO:0060136)2.19265019
150collagen fibril organization (GO:0030199)2.19249154
151cortical actin cytoskeleton organization (GO:0030866)2.19144966
152collagen catabolic process (GO:0030574)2.18922127
153I-kappaB phosphorylation (GO:0007252)2.18818113
154tolerance induction (GO:0002507)2.18108878
155myeloid cell activation involved in immune response (GO:0002275)2.17765755
156response to host immune response (GO:0052572)2.17556388
157response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.17556388
158angiogenesis involved in wound healing (GO:0060055)2.17516036
159fibrinolysis (GO:0042730)2.17310371
160positive regulation of coagulation (GO:0050820)2.17170468
161detection of external biotic stimulus (GO:0098581)2.16673485
162positive regulation of tumor necrosis factor production (GO:0032760)2.16104340

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.86099107
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.32132640
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.29749354
4BP1_19119308_ChIP-ChIP_Hs578T_Human3.25041768
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.23571385
6TP63_17297297_ChIP-ChIP_HaCaT_Human3.13279400
7* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.06449782
8FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.95214606
9* RXR_22158963_ChIP-Seq_LIVER_Mouse2.90413021
10PPARA_22158963_ChIP-Seq_LIVER_Mouse2.69935573
11SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.68993132
12MYB_21317192_ChIP-Seq_ERMYB_Mouse2.67585863
13PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.65960909
14NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.53383791
15LXR_22158963_ChIP-Seq_LIVER_Mouse2.53013245
16STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.51381344
17IRF8_21731497_ChIP-ChIP_J774_Mouse2.45396656
18* IRF8_27001747_Chip-Seq_BMDM_Mouse2.45376671
19SCL_19346495_ChIP-Seq_HPC-7_Human2.41398667
20IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.41134955
21TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.39396315
22MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.36874978
23NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.21388784
24BRD4_27068464_Chip-Seq_AML-cells_Mouse2.16987487
25Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.16658825
26CLOCK_20551151_ChIP-Seq_293T_Human2.15713984
27VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.11220271
28RARG_19884340_ChIP-ChIP_MEFs_Mouse2.00369841
29RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.00186215
30VDR_21846776_ChIP-Seq_THP-1_Human2.00180766
31TRIM28_21343339_ChIP-Seq_HEK293_Human1.99677500
32SMAD_19615063_ChIP-ChIP_OVARY_Human1.90112743
33STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.88608419
34TCF7_22412390_ChIP-Seq_EML_Mouse1.87560054
35CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.85647200
36RUNX_20019798_ChIP-Seq_JUKART_Human1.77363837
37ELK3_25401928_ChIP-Seq_HUVEC_Human1.74154932
38NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.72003093
39TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.71892758
40* EGR1_23403033_ChIP-Seq_LIVER_Mouse1.71305361
41VDR_24763502_ChIP-Seq_THP-1_Human1.71025655
42MAF_26560356_Chip-Seq_TH1_Human1.67078845
43GATA1_22025678_ChIP-Seq_K562_Human1.66961584
44FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.65849351
45GATA2_21666600_ChIP-Seq_HMVEC_Human1.61492552
46RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.58819168
47MYC_22102868_ChIP-Seq_BL_Human1.58645438
48KDM2B_26808549_Chip-Seq_SUP-B15_Human1.57972097
49FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.56468565
50STAT6_21828071_ChIP-Seq_BEAS2B_Human1.50914168
51THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.49487238
52IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.45398570
53KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.43308303
54SPI1_23127762_ChIP-Seq_K562_Human1.41722967
55UTX_26944678_Chip-Seq_JUKART_Human1.40348548
56RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.40175659
57GATA1_19941826_ChIP-Seq_K562_Human1.37746398
58MYB_26560356_Chip-Seq_TH2_Human1.37139338
59RUNX1_22412390_ChIP-Seq_EML_Mouse1.34615312
60TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.33841334
61STAT4_19710469_ChIP-ChIP_TH1__Mouse1.33546667
62MYB_26560356_Chip-Seq_TH1_Human1.31915049
63KDM2B_26808549_Chip-Seq_DND41_Human1.29897932
64PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.29539946
65STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.29487680
66KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.28458159
67VDR_24787735_ChIP-Seq_THP-1_Human1.27753574
68PU_27001747_Chip-Seq_BMDM_Mouse1.27558626
69MAF_26560356_Chip-Seq_TH2_Human1.27352990
70ESR1_21235772_ChIP-Seq_MCF-7_Human1.27271663
71* KDM2B_26808549_Chip-Seq_K562_Human1.26600358
72GATA2_19941826_ChIP-Seq_K562_Human1.25625515
73TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.25425882
74KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.24825005
75* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.22791374
76TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21926549
77CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.21778718
78* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.20823436
79FOXO3_23340844_ChIP-Seq_DLD1_Human1.19895946
80SPI1_23547873_ChIP-Seq_NB4_Human1.19618242
81PPAR_26484153_Chip-Seq_NCI-H1993_Human1.18267768
82LXR_22292898_ChIP-Seq_THP-1_Human1.17981464
83* GATA1_19941827_ChIP-Seq_MEL_Mouse1.17577278
84CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.14955512
85* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.13941071
86PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.12631427
87ESR2_21235772_ChIP-Seq_MCF-7_Human1.12405881
88PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.12028110
89ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.10355706
90GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09190620
91CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.08926875
92* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.05836716
93SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.04738308
94SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.04738308
95NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.03481339
96* NCOR1_26117541_ChIP-Seq_K562_Human1.03386238
97* RACK7_27058665_Chip-Seq_MCF-7_Human1.02554346
98* CJUN_26792858_Chip-Seq_BT549_Human1.02281402
99ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.01246498
100PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.00471844
101KDM2B_26808549_Chip-Seq_JURKAT_Human0.99894790
102SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98751505
103CTCF_27219007_Chip-Seq_ERYTHROID_Human0.97984335
104SMC1_22415368_ChIP-Seq_MEFs_Mouse0.97923984
105KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.96820435
106P63_26484246_Chip-Seq_KERATINOCYTES_Human0.96090279
107* P300_27058665_Chip-Seq_ZR-75-30cells_Human0.95937383
108FOXA2_19822575_ChIP-Seq_HepG2_Human0.95501851
109LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.95324031
110* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.94894659
111GATA1_22383799_ChIP-Seq_G1ME_Mouse0.94415617
112EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.94293743
113CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.94279515
114GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.93684312
115SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.92062061
116GATA2_22383799_ChIP-Seq_G1ME_Mouse0.91533459
117TBX20_22328084_ChIP-Seq_HEART_Mouse0.91529496
118TBX20_22080862_ChIP-Seq_HEART_Mouse0.91529496

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen4.03022493
2MP0003705_abnormal_hypodermis_morpholog3.24755888
3MP0005275_abnormal_skin_tensile2.48053870
4MP0003300_gastrointestinal_ulcer2.33313454
5MP0009278_abnormal_bone_marrow2.23126174
6MP0003724_increased_susceptibility_to2.19402961
7MP0003303_peritoneal_inflammation2.18007537
8MP0003436_decreased_susceptibility_to2.17904458
9MP0003279_aneurysm1.98187867
10MP0009840_abnormal_foam_cell1.90514606
11MP0001958_emphysema1.88136837
12MP0002419_abnormal_innate_immunity1.81318888
13MP0001545_abnormal_hematopoietic_system1.81039480
14MP0005397_hematopoietic_system_phenotyp1.81039480
15MP0003566_abnormal_cell_adhesion1.80812723
16MP0005451_abnormal_body_composition1.79860413
17MP0002166_altered_tumor_susceptibility1.77851752
18MP0005503_abnormal_tendon_morphology1.77561527
19MP0002139_abnormal_hepatobiliary_system1.77206236
20MP0001835_abnormal_antigen_presentation1.76976176
21MP0005360_urolithiasis1.75689955
22MP0003191_abnormal_cellular_cholesterol1.74702588
23MP0005058_abnormal_lysosome_morphology1.71963476
24MP0006054_spinal_hemorrhage1.71388231
25MP0000685_abnormal_immune_system1.71350027
26MP0005464_abnormal_platelet_physiology1.71255865
27MP0002254_reproductive_system_inflammat1.67208258
28MP0005023_abnormal_wound_healing1.66710490
29MP0002060_abnormal_skin_morphology1.63575476
30MP0009785_altered_susceptibility_to1.62698746
31MP0000569_abnormal_digit_pigmentation1.58430282
32MP0010368_abnormal_lymphatic_system1.56654936
33MP0001533_abnormal_skeleton_physiology1.54897434
34MP0004947_skin_inflammation1.54605787
35MP0005025_abnormal_response_to1.53155651
36MP0010352_gastrointestinal_tract_polyps1.49615973
37MP0005365_abnormal_bile_salt1.39240833
38MP0002396_abnormal_hematopoietic_system1.37607101
39MP0010329_abnormal_lipoprotein_level1.36826898
40MP0008260_abnormal_autophagy1.36259587
41MP0003252_abnormal_bile_duct1.36250116
42MP0000343_altered_response_to1.34273816
43MP0005076_abnormal_cell_differentiation1.33991303
44MP0002006_tumorigenesis1.33943898
45MP0006082_CNS_inflammation1.32864407
46MP0001790_abnormal_immune_system1.31266872
47MP0005387_immune_system_phenotype1.31266872
48MP0004272_abnormal_basement_membrane1.31037417
49MP0000767_abnormal_smooth_muscle1.27818416
50MP0005000_abnormal_immune_tolerance1.25526549
51MP0002998_abnormal_bone_remodeling1.23426733
52MP0002452_abnormal_antigen_presenting1.22361643
53MP0000465_gastrointestinal_hemorrhage1.22254113
54MP0004883_abnormal_blood_vessel1.21415823
55MP0000604_amyloidosis1.21240579
56MP0001800_abnormal_humoral_immune1.20236873
57MP0005085_abnormal_gallbladder_physiolo1.19051383
58MP0004808_abnormal_hematopoietic_stem1.15503147
59MP0001243_abnormal_dermal_layer1.14382379
60MP0002405_respiratory_system_inflammati1.13703729
61MP0005167_abnormal_blood-brain_barrier1.13321803
62MP0000858_altered_metastatic_potential1.12652099
63MP0001845_abnormal_inflammatory_respons1.12619732
64MP0005671_abnormal_response_to1.11315002
65MP0002398_abnormal_bone_marrow1.11244111
66MP0009764_decreased_sensitivity_to1.11211958
67MP0003448_altered_tumor_morphology1.11056047
68MP0010155_abnormal_intestine_physiology1.08991164
69MP0001879_abnormal_lymphatic_vessel1.08615744
70MP0003091_abnormal_cell_migration1.08614387
71MP0000609_abnormal_liver_physiology1.07726468
72MP0003075_altered_response_to1.07601266
73MP0002420_abnormal_adaptive_immunity1.07022927
74MP0001873_stomach_inflammation1.06985063
75MP0002148_abnormal_hypersensitivity_rea1.06864051
76MP0001819_abnormal_immune_cell1.06618928
77MP0004510_myositis1.04739033
78MP0002723_abnormal_immune_serum1.04676175
79MP0008469_abnormal_protein_level1.04296460
80MP0003453_abnormal_keratinocyte_physiol1.03463020
81MP0001851_eye_inflammation1.03368816
82MP0005083_abnormal_biliary_tract1.03337029
83MP0008004_abnormal_stomach_pH1.03313243
84MP0001849_ear_inflammation1.02660421
85MP0005390_skeleton_phenotype1.01522653
86MP0004185_abnormal_adipocyte_glucose1.01101239
87MP0005257_abnormal_intraocular_pressure1.00763976
88MP0005409_darkened_coat_color1.00214732
89MP0003172_abnormal_lysosome_physiology0.98164114
90MP0010307_abnormal_tumor_latency0.97596849
91MP0001542_abnormal_bone_strength0.97291806
92MP0002138_abnormal_hepatobiliary_system0.97008695
93MP0009384_cardiac_valve_regurgitation0.95242212
94MP0001853_heart_inflammation0.95201990
95MP0002933_joint_inflammation0.94686552
96MP0003828_pulmonary_edema0.94054099
97MP0002722_abnormal_immune_system0.93756274
98MP0000249_abnormal_blood_vessel0.93272718
99MP0005164_abnormal_response_to0.91079607
100MP0003183_abnormal_peptide_metabolism0.90669686
101MP0009763_increased_sensitivity_to0.90221537
102MP0002429_abnormal_blood_cell0.90075061
103MP0003690_abnormal_glial_cell0.88692638
104MP0003866_abnormal_defecation0.87840629
105MP0002877_abnormal_melanocyte_morpholog0.87610998
106MP0001915_intracranial_hemorrhage0.87493409
107MP0000689_abnormal_spleen_morphology0.86830292
108MP0003656_abnormal_erythrocyte_physiolo0.86397319
109MP0005666_abnormal_adipose_tissue0.86046964
110MP0003795_abnormal_bone_structure0.85895213
111MP0009333_abnormal_splenocyte_physiolog0.83880949
112MP0002132_abnormal_respiratory_system0.83272761
113MP0003763_abnormal_thymus_physiology0.83097835
114MP0008875_abnormal_xenobiotic_pharmacok0.82959775
115MP0003045_fibrosis0.82479861
116MP0005670_abnormal_white_adipose0.81868387
117MP0004130_abnormal_muscle_cell0.81773657
118MP0005166_decreased_susceptibility_to0.81333156
119MP0000703_abnormal_thymus_morphology0.81011422
120MP0002295_abnormal_pulmonary_circulatio0.80851836
121MP0009115_abnormal_fat_cell0.80710316
122MP0000716_abnormal_immune_system0.80383165

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)4.16466855
2Eczematoid dermatitis (HP:0000976)3.59851037
3Broad metatarsal (HP:0001783)3.47575059
4Peritonitis (HP:0002586)3.42131908
5Cerebral aneurysm (HP:0004944)3.41443766
6Deep venous thrombosis (HP:0002625)3.33894903
7Hematochezia (HP:0002573)3.27321110
8Premature rupture of membranes (HP:0001788)3.27138458
9Complement deficiency (HP:0004431)3.25876431
10Ankle contracture (HP:0006466)3.25781156
11Systemic lupus erythematosus (HP:0002725)3.25018962
12Recurrent gram-negative bacterial infections (HP:0005420)3.23204670
13Aortic dissection (HP:0002647)3.22203923
14Spontaneous hematomas (HP:0007420)3.08844903
15Aortic aneurysm (HP:0004942)2.88364319
16Myocardial infarction (HP:0001658)2.85356137
17Periodontitis (HP:0000704)2.84188542
18Recurrent abscess formation (HP:0002722)2.83642338
19Joint hemorrhage (HP:0005261)2.82957818
20Shallow orbits (HP:0000586)2.80111260
21Abnormality of glycolipid metabolism (HP:0010969)2.76264349
22Abnormality of liposaccharide metabolism (HP:0010968)2.76264349
23Abnormality of glycosphingolipid metabolism (HP:0004343)2.76264349
24Osteolytic defects of the hand bones (HP:0009699)2.75553716
25Osteolytic defects of the phalanges of the hand (HP:0009771)2.75553716
26Abnormality of complement system (HP:0005339)2.74877512
27Recurrent bacterial skin infections (HP:0005406)2.72710443
28Glomerulonephritis (HP:0000099)2.72003948
29Vascular tortuosity (HP:0004948)2.70358332
30Abnormality of the common coagulation pathway (HP:0010990)2.69505693
31Mitral valve prolapse (HP:0001634)2.58824453
32Cervical subluxation (HP:0003308)2.52740940
33Arterial tortuosity (HP:0005116)2.50372982
34Gastrointestinal infarctions (HP:0005244)2.50226948
35Atrophic scars (HP:0001075)2.49436659
36Xanthomatosis (HP:0000991)2.42574235
37Dilatation of the ascending aorta (HP:0005111)2.40608777
38Gingival bleeding (HP:0000225)2.39330748
39Spondylolisthesis (HP:0003302)2.38288853
40Cellulitis (HP:0100658)2.38133425
41Myositis (HP:0100614)2.36725105
42Increased IgE level (HP:0003212)2.36540137
43Arterial thrombosis (HP:0004420)2.35779248
44Epistaxis (HP:0000421)2.33910348
45Esophageal varix (HP:0002040)2.33909209
46Nephritis (HP:0000123)2.33604347
47Retrobulbar optic neuritis (HP:0100654)2.27395100
48Optic neuritis (HP:0100653)2.27395100
49Abnormality of polysaccharide metabolism (HP:0011012)2.23275117
50Abnormality of glycosaminoglycan metabolism (HP:0004371)2.23275117
51Abnormality of mucopolysaccharide metabolism (HP:0011020)2.23275117
52Emphysema (HP:0002097)2.20007428
53Asymmetry of the thorax (HP:0001555)2.18317867
54Increased variability in muscle fiber diameter (HP:0003557)2.17583734
55Pustule (HP:0200039)2.17308982
56Increased connective tissue (HP:0009025)2.17305092
57Recurrent fungal infections (HP:0002841)2.16682217
58Pulmonary embolism (HP:0002204)2.14336587
59Elevated erythrocyte sedimentation rate (HP:0003565)2.13172049
60Recurrent skin infections (HP:0001581)2.10380573
61Abnormality of macrophages (HP:0004311)2.09617444
62Mitral stenosis (HP:0001718)2.08719785
63Gingivitis (HP:0000230)2.08367369
64Fragile skin (HP:0001030)2.08157150
65Follicular hyperkeratosis (HP:0007502)2.07994789
66Thoracic kyphosis (HP:0002942)2.07729047
67Aneurysm (HP:0002617)2.06871190
68Abnormality of the nasal mucosa (HP:0000433)2.06501162
69Wormian bones (HP:0002645)2.05610630
70Orchitis (HP:0100796)2.05360413
71Vacuolated lymphocytes (HP:0001922)2.03273930
72Prolonged bleeding time (HP:0003010)2.03198165
73Ulnar bowing (HP:0003031)2.02455397
74Autoimmune thrombocytopenia (HP:0001973)2.02048134
75Persistence of primary teeth (HP:0006335)2.01086580
76Syringomyelia (HP:0003396)2.00782450
77Spinal cord lesions (HP:0100561)2.00782450
78Recurrent cutaneous fungal infections (HP:0011370)2.00698724
79Chronic mucocutaneous candidiasis (HP:0002728)2.00698724
80Meningitis (HP:0001287)2.00378204
81Slender build (HP:0001533)1.99834311
82Prolonged partial thromboplastin time (HP:0003645)1.98918803
83Menorrhagia (HP:0000132)1.98877902
84Recurrent viral infections (HP:0004429)1.98003480
85Vasculitis (HP:0002633)1.97947304
86Amyloidosis (HP:0011034)1.97250287
87Disproportionate tall stature (HP:0001519)1.95685823
88Blue sclerae (HP:0000592)1.95604709
89Increased cerebral lipofuscin (HP:0011813)1.95080595
90Pulmonary infiltrates (HP:0002113)1.93135835
91Abnormal platelet volume (HP:0011876)1.92925363
92Hemoptysis (HP:0002105)1.92717332
93Impaired platelet aggregation (HP:0003540)1.91969512
94Abnormal platelet function (HP:0011869)1.91969512
95Chronic otitis media (HP:0000389)1.91128555
96Abnormality of skeletal muscle fiber size (HP:0012084)1.89660026
97Loss of speech (HP:0002371)1.89653650
98Vertebral compression fractures (HP:0002953)1.89367368
99Obstructive lung disease (HP:0006536)1.89066344
100Chronic obstructive pulmonary disease (HP:0006510)1.89066344
101Inflammation of the large intestine (HP:0002037)1.88570426
102Alopecia of scalp (HP:0002293)1.88501026
103Soft skin (HP:0000977)1.87689144
104Gastrointestinal inflammation (HP:0004386)1.87232940
105Urinary glycosaminoglycan excretion (HP:0003541)1.86558129
106Mucopolysacchariduria (HP:0008155)1.86558129
107Increased mean platelet volume (HP:0011877)1.86214917
108Thrombophlebitis (HP:0004418)1.85987440
109Dysostosis multiplex (HP:0000943)1.85711193
110Bruising susceptibility (HP:0000978)1.85202280
111Hemorrhage of the eye (HP:0011885)1.85125336
112Abnormality of the lumbar spine (HP:0100712)1.85120569
113Striae distensae (HP:0001065)1.85026717
114Polycythemia (HP:0001901)1.84938993
115Abnormality of the peritoneum (HP:0002585)1.84690842
116Genu recurvatum (HP:0002816)1.84507606
117Thick nail (HP:0001805)1.83269304
118Colitis (HP:0002583)1.82839919
119Keratoconjunctivitis sicca (HP:0001097)1.82739563
120Mediastinal lymphadenopathy (HP:0100721)1.82666299
121Bladder diverticulum (HP:0000015)1.82493252
122T lymphocytopenia (HP:0005403)1.82401121
123Wrist flexion contracture (HP:0001239)1.80731423
124Broad face (HP:0000283)1.80120400
125Ectopia lentis (HP:0001083)1.79448194
126Interstitial pulmonary disease (HP:0006530)1.78977779
127Segmental peripheral demyelination/remyelination (HP:0003481)1.78007444
128Malnutrition (HP:0004395)1.77621598
129Abnormal delayed hypersensitivity skin test (HP:0002963)1.77462100
130Joint stiffness (HP:0001387)1.76639553
131Abnormality of monocarboxylic acid metabolism (HP:0010996)1.76368769
132Polygenic inheritance (HP:0010982)1.75935452
133Abnormality of the thoracic spine (HP:0100711)1.75496997
134Lymphangioma (HP:0100764)1.75283965
135Camptodactyly of toe (HP:0001836)1.74629733
136Thin bony cortex (HP:0002753)1.74467000
137Obstructive sleep apnea (HP:0002870)1.74244987
138Joint laxity (HP:0001388)1.73527068

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.67621850
2PKN23.35501280
3PRPF4B3.22524117
4TGFBR22.97122933
5ERN12.89172938
6RIPK12.63104714
7TTN2.31761669
8TYK22.29308563
9SIK12.11959629
10TAOK32.09964420
11EPHB12.01214073
12MAP3K132.00454437
13PTK61.97952099
14KIT1.97132708
15FGFR41.96719907
16JAK11.74724143
17MAP4K11.74390773
18MAP2K31.74390485
19CAMK1D1.73750862
20JAK31.70664500
21STK101.69933725
22EEF2K1.67744626
23TBK11.64036119
24PDGFRA1.62326277
25CDC42BPA1.59690030
26FGFR21.49658418
27LATS11.46535737
28FGFR31.43106764
29MAP3K141.41791180
30LRRK21.40948029
31MAP3K101.37254996
32SMG11.33598566
33FLT31.32323516
34CSK1.31749606
35EPHA31.31483801
36ZAP701.30682015
37STK31.26916496
38IRAK31.26797237
39KDR1.25741551
40FRK1.24797265
41BLK1.16562142
42JAK21.15285153
43NEK91.14858389
44TIE11.13741467
45CAMK1G1.12708614
46ICK1.12633775
47KSR21.12192297
48MAP3K11.11293904
49IKBKE1.10389320
50MAP3K61.09990897
51ITK1.08953642
52PAK41.08546124
53PDGFRB1.06835119
54IRAK41.06756639
55MAP3K31.05629981
56MARK21.05353568
57PRKD21.02715700
58HCK1.02619648
59CDK60.98203635
60BTK0.96983799
61DDR20.95257720
62TRPM70.94857273
63PDPK10.94775264
64MST1R0.94372053
65IKBKB0.92743450
66SYK0.88980316
67CLK10.85859372
68BMX0.84435692
69TEC0.81953598
70MOS0.81327603
71CSF1R0.80552721
72TXK0.80307390
73TNK20.79838992
74CDK120.79711552
75PAK20.78855912
76TGFBR10.78637707
77PDK10.76394826
78PTK20.74785415
79FGR0.74723989
80TAOK20.73725950
81DMPK0.73447735
82HIPK20.73323316
83STK380.71037129
84CHUK0.70370061
85LCK0.69806905
86MAPK110.68781870
87SIK20.67923794
88MAP3K70.67187860
89RPS6KA40.66410096
90MELK0.65479481
91MAP3K20.64431441
92GRK60.62879549
93CDK40.62577287
94MARK30.61388189
95IRAK10.61365787
96RIPK40.61073434
97PRKG20.60794917
98FES0.60207545
99RPS6KL10.59698847
100RPS6KC10.59698847
101NLK0.58851326
102MTOR0.58755777
103MATK0.54102167
104EGFR0.53453225
105PRKAA20.52868173
106PIK3CG0.52531959
107MAPK70.51985938
108PTK2B0.51828606
109PIM10.50542330
110MAPK120.50218694
111GRK70.50109568
112YES10.49427025
113SCYL20.49300288
114MAPK40.48750827
115FGFR10.48554285
116SGK30.48349666
117ABL10.48087436
118TAOK10.47531053
119STK40.42406434
120RET0.41688835
121LYN0.41485211
122CDK90.40822645
123IRAK20.39678705
124MYLK0.39562517
125GSK3A0.39374882
126MAP3K110.38914381
127RPS6KA60.38740279
128IGF1R0.38573563
129RPS6KA20.38082124

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051503.56364285
2Complement and coagulation cascades_Homo sapiens_hsa046102.64276627
3Caffeine metabolism_Homo sapiens_hsa002322.63274956
4Leishmaniasis_Homo sapiens_hsa051402.06836874
5Primary bile acid biosynthesis_Homo sapiens_hsa001201.96760983
6Nitrogen metabolism_Homo sapiens_hsa009101.95630199
7Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.78608466
8Glycosaminoglycan degradation_Homo sapiens_hsa005311.77413519
9Malaria_Homo sapiens_hsa051441.76381562
10Osteoclast differentiation_Homo sapiens_hsa043801.71764465
11ECM-receptor interaction_Homo sapiens_hsa045121.57216259
12Toxoplasmosis_Homo sapiens_hsa051451.56503749
13Pertussis_Homo sapiens_hsa051331.50612913
14Toll-like receptor signaling pathway_Homo sapiens_hsa046201.45261530
15Allograft rejection_Homo sapiens_hsa053301.44853311
16PPAR signaling pathway_Homo sapiens_hsa033201.37426712
17Arginine biosynthesis_Homo sapiens_hsa002201.36978858
18Amoebiasis_Homo sapiens_hsa051461.34424827
19AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.33399171
20Small cell lung cancer_Homo sapiens_hsa052221.33111494
21Pentose and glucuronate interconversions_Homo sapiens_hsa000401.31714958
22NF-kappa B signaling pathway_Homo sapiens_hsa040641.30730758
23Autoimmune thyroid disease_Homo sapiens_hsa053201.30108065
24ABC transporters_Homo sapiens_hsa020101.24901019
25Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.23838063
26Leukocyte transendothelial migration_Homo sapiens_hsa046701.23632937
27Chronic myeloid leukemia_Homo sapiens_hsa052201.22970800
28Lysine degradation_Homo sapiens_hsa003101.22696481
29Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.22616671
30Focal adhesion_Homo sapiens_hsa045101.22448875
31Measles_Homo sapiens_hsa051621.20587199
32Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.20052047
33TNF signaling pathway_Homo sapiens_hsa046681.19494225
34Fatty acid degradation_Homo sapiens_hsa000711.17544698
35Platelet activation_Homo sapiens_hsa046111.10530608
36Tuberculosis_Homo sapiens_hsa051521.09711346
37Lysosome_Homo sapiens_hsa041421.09408782
38Tryptophan metabolism_Homo sapiens_hsa003801.09225328
39Antigen processing and presentation_Homo sapiens_hsa046121.08739265
40VEGF signaling pathway_Homo sapiens_hsa043701.06848402
41Insulin resistance_Homo sapiens_hsa049311.05747502
42Jak-STAT signaling pathway_Homo sapiens_hsa046301.05383688
43Viral myocarditis_Homo sapiens_hsa054161.04384490
44Other glycan degradation_Homo sapiens_hsa005111.02207452
45Renal cell carcinoma_Homo sapiens_hsa052110.98369897
46Proteoglycans in cancer_Homo sapiens_hsa052050.98067450
47Influenza A_Homo sapiens_hsa051640.97575644
48Prolactin signaling pathway_Homo sapiens_hsa049170.96010864
49Acute myeloid leukemia_Homo sapiens_hsa052210.95958536
50Legionellosis_Homo sapiens_hsa051340.95835168
51Prion diseases_Homo sapiens_hsa050200.95756677
52Pancreatic cancer_Homo sapiens_hsa052120.95194002
53Apoptosis_Homo sapiens_hsa042100.94085813
54B cell receptor signaling pathway_Homo sapiens_hsa046620.93121629
55NOD-like receptor signaling pathway_Homo sapiens_hsa046210.92573151
56Starch and sucrose metabolism_Homo sapiens_hsa005000.92177592
57Phospholipase D signaling pathway_Homo sapiens_hsa040720.91620842
58Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.90602317
59Adipocytokine signaling pathway_Homo sapiens_hsa049200.90053948
60Hepatitis B_Homo sapiens_hsa051610.87740148
61Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.87250741
62Asthma_Homo sapiens_hsa053100.85198385
63Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.84788000
64Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.84457078
65Hematopoietic cell lineage_Homo sapiens_hsa046400.84437319
66African trypanosomiasis_Homo sapiens_hsa051430.84004895
67Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.81036699
68Histidine metabolism_Homo sapiens_hsa003400.79350085
69Hepatitis C_Homo sapiens_hsa051600.78923573
70RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.78910020
71GnRH signaling pathway_Homo sapiens_hsa049120.78758710
72Endometrial cancer_Homo sapiens_hsa052130.78667649
73Dorso-ventral axis formation_Homo sapiens_hsa043200.77661430
74Sphingolipid signaling pathway_Homo sapiens_hsa040710.76847024
75Type I diabetes mellitus_Homo sapiens_hsa049400.76558988
76Shigellosis_Homo sapiens_hsa051310.74403188
77Chemokine signaling pathway_Homo sapiens_hsa040620.73765628
78Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.73629077
79Phosphatidylinositol signaling system_Homo sapiens_hsa040700.73216382
80mTOR signaling pathway_Homo sapiens_hsa041500.72999497
81Herpes simplex infection_Homo sapiens_hsa051680.72641138
82Choline metabolism in cancer_Homo sapiens_hsa052310.72057743
83Adherens junction_Homo sapiens_hsa045200.70263928
84FoxO signaling pathway_Homo sapiens_hsa040680.70167309
85Intestinal immune network for IgA production_Homo sapiens_hsa046720.69528406
86Bile secretion_Homo sapiens_hsa049760.69308858
87Transcriptional misregulation in cancer_Homo sapiens_hsa052020.68749132
88Glioma_Homo sapiens_hsa052140.67771073
89Rheumatoid arthritis_Homo sapiens_hsa053230.66293178
90Chemical carcinogenesis_Homo sapiens_hsa052040.65246441
91Salmonella infection_Homo sapiens_hsa051320.64606571
92MicroRNAs in cancer_Homo sapiens_hsa052060.64325749
93Inositol phosphate metabolism_Homo sapiens_hsa005620.64152779
94Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.62644634
95Estrogen signaling pathway_Homo sapiens_hsa049150.62292543
96Endocytosis_Homo sapiens_hsa041440.62290206
97Protein digestion and absorption_Homo sapiens_hsa049740.62269315
98Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.61740155
99beta-Alanine metabolism_Homo sapiens_hsa004100.60711866
100Notch signaling pathway_Homo sapiens_hsa043300.60253014
101Drug metabolism - other enzymes_Homo sapiens_hsa009830.60243307
102Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.60084294
103Primary immunodeficiency_Homo sapiens_hsa053400.59248337
104Fatty acid metabolism_Homo sapiens_hsa012120.55980003
105Fat digestion and absorption_Homo sapiens_hsa049750.55611700
106Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.55531176
107Renin-angiotensin system_Homo sapiens_hsa046140.55435981
108HIF-1 signaling pathway_Homo sapiens_hsa040660.55352239
109Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.55181977
110Graft-versus-host disease_Homo sapiens_hsa053320.54927463
111Phagosome_Homo sapiens_hsa041450.54412257
112Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54238977
113Steroid hormone biosynthesis_Homo sapiens_hsa001400.54213010
114Bladder cancer_Homo sapiens_hsa052190.53824766
115Insulin signaling pathway_Homo sapiens_hsa049100.53703591
116Viral carcinogenesis_Homo sapiens_hsa052030.53212292
117Colorectal cancer_Homo sapiens_hsa052100.53133856
118Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52845018
119T cell receptor signaling pathway_Homo sapiens_hsa046600.52328712
120PI3K-Akt signaling pathway_Homo sapiens_hsa041510.51773023
121Rap1 signaling pathway_Homo sapiens_hsa040150.51430412
122Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51255956
123Thyroid cancer_Homo sapiens_hsa052160.50262739
124Peroxisome_Homo sapiens_hsa041460.49724871
125Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.49503463
126Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.49479055
127Central carbon metabolism in cancer_Homo sapiens_hsa052300.47859513
128Non-small cell lung cancer_Homo sapiens_hsa052230.47403410
129Neurotrophin signaling pathway_Homo sapiens_hsa047220.46809539
130Prostate cancer_Homo sapiens_hsa052150.45874403
131HTLV-I infection_Homo sapiens_hsa051660.44177260
132Retinol metabolism_Homo sapiens_hsa008300.43526284

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