

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.97171384 |
| 2 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.26905627 |
| 3 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.21103586 |
| 4 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.80803121 |
| 5 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.77968627 |
| 6 | negative regulation of cell killing (GO:0031342) | 4.77968627 |
| 7 | cellular response to type I interferon (GO:0071357) | 4.75468351 |
| 8 | type I interferon signaling pathway (GO:0060337) | 4.75468351 |
| 9 | response to type I interferon (GO:0034340) | 4.70096712 |
| 10 | positive regulation by symbiont of host defense response (GO:0052509) | 4.47636326 |
| 11 | modulation by symbiont of host defense response (GO:0052031) | 4.47636326 |
| 12 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.47636326 |
| 13 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.47636326 |
| 14 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.47636326 |
| 15 | modulation by symbiont of host immune response (GO:0052553) | 4.47636326 |
| 16 | mature B cell differentiation involved in immune response (GO:0002313) | 4.40959391 |
| 17 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.23831265 |
| 18 | fusion of sperm to egg plasma membrane (GO:0007342) | 4.11751628 |
| 19 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.02674423 |
| 20 | immunoglobulin mediated immune response (GO:0016064) | 4.01146868 |
| 21 | macrophage activation involved in immune response (GO:0002281) | 3.88125862 |
| 22 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.77578721 |
| 23 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.74587359 |
| 24 | natural killer cell differentiation (GO:0001779) | 3.67366128 |
| 25 | mature B cell differentiation (GO:0002335) | 3.65516974 |
| 26 | detection of bacterium (GO:0016045) | 3.62363680 |
| 27 | response to host immune response (GO:0052572) | 3.55924935 |
| 28 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.55924935 |
| 29 | response to peptidoglycan (GO:0032494) | 3.53370458 |
| 30 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.53124087 |
| 31 | Peyers patch development (GO:0048541) | 3.53124087 |
| 32 | detection of other organism (GO:0098543) | 3.48811893 |
| 33 | positive regulation of type 2 immune response (GO:0002830) | 3.48321404 |
| 34 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.45611597 |
| 35 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.45376040 |
| 36 | positive thymic T cell selection (GO:0045059) | 3.45358618 |
| 37 | phosphatidylethanolamine biosynthetic process (GO:0006646) | 3.43496359 |
| 38 | negative regulation of interleukin-12 production (GO:0032695) | 3.37470639 |
| 39 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.37057650 |
| 40 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.31120006 |
| 41 | sperm motility (GO:0030317) | 3.28777788 |
| 42 | response to host (GO:0075136) | 3.27055530 |
| 43 | response to host defenses (GO:0052200) | 3.27055530 |
| 44 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.27055530 |
| 45 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.22100354 |
| 46 | defense response to protozoan (GO:0042832) | 3.21634444 |
| 47 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.21023105 |
| 48 | regulation of gamma-delta T cell activation (GO:0046643) | 3.20832157 |
| 49 | NIK/NF-kappaB signaling (GO:0038061) | 3.20305297 |
| 50 | detection of external biotic stimulus (GO:0098581) | 3.20201122 |
| 51 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.18182203 |
| 52 | acrosome reaction (GO:0007340) | 3.18000794 |
| 53 | response to interferon-beta (GO:0035456) | 3.17661420 |
| 54 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.13815748 |
| 55 | phosphatidylethanolamine metabolic process (GO:0046337) | 3.06087965 |
| 56 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.05754637 |
| 57 | detection of molecule of bacterial origin (GO:0032490) | 3.05162727 |
| 58 | regulation of B cell differentiation (GO:0045577) | 3.05013462 |
| 59 | B cell mediated immunity (GO:0019724) | 3.03968557 |
| 60 | myeloid cell activation involved in immune response (GO:0002275) | 3.01451196 |
| 61 | germinal center formation (GO:0002467) | 3.00944909 |
| 62 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.98436531 |
| 63 | seminiferous tubule development (GO:0072520) | 2.98182043 |
| 64 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.97589414 |
| 65 | cellular response to interferon-gamma (GO:0071346) | 2.91798783 |
| 66 | B cell receptor signaling pathway (GO:0050853) | 2.91317203 |
| 67 | cellular response to interferon-beta (GO:0035458) | 2.91070625 |
| 68 | response to protozoan (GO:0001562) | 2.90666656 |
| 69 | response to muramyl dipeptide (GO:0032495) | 2.90114952 |
| 70 | regulation of mast cell degranulation (GO:0043304) | 2.88310697 |
| 71 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.87659851 |
| 72 | sperm capacitation (GO:0048240) | 2.84557210 |
| 73 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.84508603 |
| 74 | regulation of cytokine secretion involved in immune response (GO:0002739) | 2.84487271 |
| 75 | plasma membrane fusion (GO:0045026) | 2.84220317 |
| 76 | positive regulation of interleukin-4 production (GO:0032753) | 2.84008593 |
| 77 | regulation of interferon-alpha production (GO:0032647) | 2.80222277 |
| 78 | positive regulation of B cell differentiation (GO:0045579) | 2.78315501 |
| 79 | positive regulation of interleukin-17 production (GO:0032740) | 2.77613129 |
| 80 | response to interferon-gamma (GO:0034341) | 2.77019844 |
| 81 | negative regulation of granulocyte differentiation (GO:0030853) | 2.74385903 |
| 82 | hemoglobin metabolic process (GO:0020027) | 2.73962644 |
| 83 | positive regulation of interferon-alpha production (GO:0032727) | 2.73748961 |
| 84 | regulation of Rab GTPase activity (GO:0032313) | 2.73737800 |
| 85 | positive regulation of Rab GTPase activity (GO:0032851) | 2.73737800 |
| 86 | positive regulation of macrophage cytokine production (GO:0060907) | 2.72585954 |
| 87 | neutrophil activation involved in immune response (GO:0002283) | 2.71964498 |
| 88 | response to interleukin-15 (GO:0070672) | 2.71923938 |
| 89 | regulation of antigen processing and presentation (GO:0002577) | 2.70923388 |
| 90 | negative regulation of alpha-beta T cell activation (GO:0046636) | 2.68668710 |
| 91 | macrophage activation (GO:0042116) | 2.67848005 |
| 92 | detection of biotic stimulus (GO:0009595) | 2.67786665 |
| 93 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.66225577 |
| 94 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 2.65637075 |
| 95 | response to interferon-alpha (GO:0035455) | 2.64140052 |
| 96 | regulation of type 2 immune response (GO:0002828) | 2.63529172 |
| 97 | megakaryocyte development (GO:0035855) | 2.63518987 |
| 98 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.60877018 |
| 99 | positive regulation of antigen processing and presentation (GO:0002579) | 2.60386261 |
| 100 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.59410324 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.07631273 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.90246423 |
| 3 | GATA1_19941826_ChIP-Seq_K562_Human | 2.64595700 |
| 4 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.64455941 |
| 5 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.62611186 |
| 6 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.56280647 |
| 7 | MYC_22102868_ChIP-Seq_BL_Human | 2.52762119 |
| 8 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.52186917 |
| 9 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.45775056 |
| 10 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.43793590 |
| 11 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.41026739 |
| 12 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.39884149 |
| 13 | MAF_26560356_Chip-Seq_TH1_Human | 2.33988682 |
| 14 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.33678190 |
| 15 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.25617545 |
| 16 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.18770186 |
| 17 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.18125513 |
| 18 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.16593737 |
| 19 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.16269035 |
| 20 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 2.15735198 |
| 21 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.14200773 |
| 22 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.08868401 |
| 23 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.04647300 |
| 24 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.00929276 |
| 25 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.00904970 |
| 26 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.95595111 |
| 27 | MYB_26560356_Chip-Seq_TH2_Human | 1.95449025 |
| 28 | UTX_26944678_Chip-Seq_JUKART_Human | 1.95282401 |
| 29 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.95018457 |
| 30 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.94655231 |
| 31 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.94482173 |
| 32 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.94435280 |
| 33 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.93394561 |
| 34 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.88469674 |
| 35 | MAF_26560356_Chip-Seq_TH2_Human | 1.86348450 |
| 36 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.86230713 |
| 37 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.85112425 |
| 38 | SPI1_23127762_ChIP-Seq_K562_Human | 1.83736432 |
| 39 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.79540467 |
| 40 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.75396896 |
| 41 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.75354966 |
| 42 | MYB_26560356_Chip-Seq_TH1_Human | 1.73845331 |
| 43 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.68186531 |
| 44 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.68077494 |
| 45 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.66846700 |
| 46 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.64386055 |
| 47 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.63899110 |
| 48 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.58244436 |
| 49 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.58241541 |
| 50 | P68_20966046_ChIP-Seq_HELA_Human | 1.57382275 |
| 51 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.53321322 |
| 52 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.51332943 |
| 53 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.49235433 |
| 54 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.48745988 |
| 55 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.48331890 |
| 56 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.46747127 |
| 57 | GATA2_19941826_ChIP-Seq_K562_Human | 1.46444547 |
| 58 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.44027933 |
| 59 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.41900138 |
| 60 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.41699359 |
| 61 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.40734093 |
| 62 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.40396656 |
| 63 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.40225625 |
| 64 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.39617125 |
| 65 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.39318797 |
| 66 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.38831714 |
| 67 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.38725435 |
| 68 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.36749719 |
| 69 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.34609605 |
| 70 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.31985185 |
| 71 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.30868154 |
| 72 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.30739712 |
| 73 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.30523637 |
| 74 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.29389787 |
| 75 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.28554871 |
| 76 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.27687844 |
| 77 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.27333140 |
| 78 | P300_27268052_Chip-Seq_Bcells_Human | 1.26998856 |
| 79 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.21551820 |
| 80 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.21492681 |
| 81 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.19885154 |
| 82 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.18840073 |
| 83 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.15114985 |
| 84 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.11934245 |
| 85 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.09847347 |
| 86 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.09433827 |
| 87 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.08915338 |
| 88 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.07958508 |
| 89 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07047476 |
| 90 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.05926431 |
| 91 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.05701898 |
| 92 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.04707558 |
| 93 | CTCF_21964334_Chip-Seq_Bcells_Human | 1.03623602 |
| 94 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.03192803 |
| 95 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.02599834 |
| 96 | SA1_27219007_Chip-Seq_Bcells_Human | 1.02266085 |
| 97 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.00283082 |
| 98 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.00188237 |
| 99 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.00105785 |
| 100 | GATA1_22025678_ChIP-Seq_K562_Human | 1.00091663 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003303_peritoneal_inflammation | 3.92121338 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.61583905 |
| 3 | MP0003436_decreased_susceptibility_to | 3.51798574 |
| 4 | MP0005410_abnormal_fertilization | 3.36038660 |
| 5 | MP0000685_abnormal_immune_system | 2.91493383 |
| 6 | MP0003724_increased_susceptibility_to | 2.89405833 |
| 7 | MP0009278_abnormal_bone_marrow | 2.89238841 |
| 8 | MP0001790_abnormal_immune_system | 2.86224917 |
| 9 | MP0005387_immune_system_phenotype | 2.86224917 |
| 10 | MP0005000_abnormal_immune_tolerance | 2.83245507 |
| 11 | MP0009785_altered_susceptibility_to | 2.77760177 |
| 12 | MP0003191_abnormal_cellular_cholesterol | 2.71776742 |
| 13 | MP0005671_abnormal_response_to | 2.71491675 |
| 14 | MP0005025_abnormal_response_to | 2.62164371 |
| 15 | MP0002132_abnormal_respiratory_system | 2.52041900 |
| 16 | MP0002419_abnormal_innate_immunity | 2.50819347 |
| 17 | MP0001800_abnormal_humoral_immune | 2.46305300 |
| 18 | MP0001545_abnormal_hematopoietic_system | 2.41691565 |
| 19 | MP0005397_hematopoietic_system_phenotyp | 2.41691565 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 2.39377018 |
| 21 | MP0002723_abnormal_immune_serum | 2.37195456 |
| 22 | MP0005083_abnormal_biliary_tract | 2.27728851 |
| 23 | MP0005464_abnormal_platelet_physiology | 2.24742368 |
| 24 | MP0002452_abnormal_antigen_presenting | 2.24277861 |
| 25 | MP0004510_myositis | 2.19887710 |
| 26 | MP0002420_abnormal_adaptive_immunity | 2.17185304 |
| 27 | MP0001819_abnormal_immune_cell | 2.13982544 |
| 28 | MP0005310_abnormal_salivary_gland | 2.02864291 |
| 29 | MP0003300_gastrointestinal_ulcer | 1.98361386 |
| 30 | MP0001348_abnormal_lacrimal_gland | 1.97358178 |
| 31 | MP0009840_abnormal_foam_cell | 1.94336386 |
| 32 | MP0002398_abnormal_bone_marrow | 1.85882139 |
| 33 | MP0009333_abnormal_splenocyte_physiolog | 1.85462286 |
| 34 | MP0005451_abnormal_body_composition | 1.81024097 |
| 35 | MP0002396_abnormal_hematopoietic_system | 1.80069611 |
| 36 | MP0003763_abnormal_thymus_physiology | 1.79152205 |
| 37 | MP0002405_respiratory_system_inflammati | 1.76640283 |
| 38 | MP0003172_abnormal_lysosome_physiology | 1.72533382 |
| 39 | MP0002138_abnormal_hepatobiliary_system | 1.72476160 |
| 40 | MP0000716_abnormal_immune_system | 1.70967947 |
| 41 | MP0006082_CNS_inflammation | 1.67233345 |
| 42 | MP0005377_hearing/vestibular/ear_phenot | 1.65035915 |
| 43 | MP0003878_abnormal_ear_physiology | 1.65035915 |
| 44 | MP0001533_abnormal_skeleton_physiology | 1.60938075 |
| 45 | MP0004947_skin_inflammation | 1.53856435 |
| 46 | MP0009764_decreased_sensitivity_to | 1.50858051 |
| 47 | MP0001845_abnormal_inflammatory_respons | 1.46781791 |
| 48 | MP0002722_abnormal_immune_system | 1.45997514 |
| 49 | MP0008469_abnormal_protein_level | 1.45779404 |
| 50 | MP0002429_abnormal_blood_cell | 1.43629103 |
| 51 | MP0010155_abnormal_intestine_physiology | 1.38053969 |
| 52 | MP0000689_abnormal_spleen_morphology | 1.37709951 |
| 53 | MP0003866_abnormal_defecation | 1.36038112 |
| 54 | MP0003656_abnormal_erythrocyte_physiolo | 1.32781009 |
| 55 | MP0000465_gastrointestinal_hemorrhage | 1.23402286 |
| 56 | MP0000703_abnormal_thymus_morphology | 1.20164702 |
| 57 | MP0008874_decreased_physiological_sensi | 1.12919132 |
| 58 | MP0004883_abnormal_blood_vessel | 1.09775974 |
| 59 | MP0002653_abnormal_ependyma_morphology | 1.06113006 |
| 60 | MP0001853_heart_inflammation | 1.04856529 |
| 61 | MP0005164_abnormal_response_to | 1.03270976 |
| 62 | MP0003075_altered_response_to | 1.03182783 |
| 63 | MP0002998_abnormal_bone_remodeling | 1.00063479 |
| 64 | MP0001873_stomach_inflammation | 0.98254661 |
| 65 | MP0003183_abnormal_peptide_metabolism | 0.97672329 |
| 66 | MP0000858_altered_metastatic_potential | 0.90889508 |
| 67 | MP0008004_abnormal_stomach_pH | 0.87631755 |
| 68 | MP0001851_eye_inflammation | 0.87629135 |
| 69 | MP0008260_abnormal_autophagy | 0.86361855 |
| 70 | MP0002933_joint_inflammation | 0.83930406 |
| 71 | MP0005379_endocrine/exocrine_gland_phen | 0.83736870 |
| 72 | MP0003448_altered_tumor_morphology | 0.83731034 |
| 73 | MP0003091_abnormal_cell_migration | 0.83022691 |
| 74 | MP0000249_abnormal_blood_vessel | 0.82673995 |
| 75 | MP0003828_pulmonary_edema | 0.82111812 |
| 76 | MP0002822_catalepsy | 0.78422289 |
| 77 | MP0003698_abnormal_male_reproductive | 0.78409480 |
| 78 | MP0009763_increased_sensitivity_to | 0.75860746 |
| 79 | MP0005166_decreased_susceptibility_to | 0.75427467 |
| 80 | MP0005666_abnormal_adipose_tissue | 0.75290271 |
| 81 | MP0004808_abnormal_hematopoietic_stem | 0.74431537 |
| 82 | MP0000343_altered_response_to | 0.74406387 |
| 83 | MP0009765_abnormal_xenobiotic_induced | 0.71290169 |
| 84 | MP0005390_skeleton_phenotype | 0.70272752 |
| 85 | MP0002166_altered_tumor_susceptibility | 0.69601994 |
| 86 | MP0001663_abnormal_digestive_system | 0.68249594 |
| 87 | MP0002006_tumorigenesis | 0.67903176 |
| 88 | MP0002019_abnormal_tumor_incidence | 0.67663422 |
| 89 | MP0005670_abnormal_white_adipose | 0.64170037 |
| 90 | MP0005535_abnormal_body_temperature | 0.64131272 |
| 91 | MP0003879_abnormal_hair_cell | 0.63597682 |
| 92 | MP0003453_abnormal_keratinocyte_physiol | 0.62893537 |
| 93 | MP0000604_amyloidosis | 0.62078673 |
| 94 | MP0000678_abnormal_parathyroid_gland | 0.61489336 |
| 95 | MP0001929_abnormal_gametogenesis | 0.60698187 |
| 96 | MP0005623_abnormal_meninges_morphology | 0.59896818 |
| 97 | MP0005165_increased_susceptibility_to | 0.53265174 |
| 98 | MP0006054_spinal_hemorrhage | 0.52803067 |
| 99 | MP0005319_abnormal_enzyme/_coenzyme | 0.52368502 |
| 100 | MP0005375_adipose_tissue_phenotype | 0.51673200 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Myositis (HP:0100614) | 5.63248871 |
| 2 | Orchitis (HP:0100796) | 5.26574980 |
| 3 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.65315759 |
| 4 | Retrobulbar optic neuritis (HP:0100654) | 4.56574323 |
| 5 | Optic neuritis (HP:0100653) | 4.56574323 |
| 6 | Severe visual impairment (HP:0001141) | 4.18033629 |
| 7 | Recurrent abscess formation (HP:0002722) | 3.88806691 |
| 8 | Cellulitis (HP:0100658) | 3.84970040 |
| 9 | Abnormality of macrophages (HP:0004311) | 3.83246955 |
| 10 | Increased IgE level (HP:0003212) | 3.73981609 |
| 11 | Eczematoid dermatitis (HP:0000976) | 3.72833257 |
| 12 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 3.68643368 |
| 13 | Meningitis (HP:0001287) | 3.64218598 |
| 14 | Vasculitis (HP:0002633) | 3.59119420 |
| 15 | Recurrent bacterial skin infections (HP:0005406) | 3.48828567 |
| 16 | Gastrointestinal infarctions (HP:0005244) | 3.46449923 |
| 17 | Nasal polyposis (HP:0100582) | 3.44118265 |
| 18 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 3.36424867 |
| 19 | Stomatitis (HP:0010280) | 3.35220421 |
| 20 | Asymmetric septal hypertrophy (HP:0001670) | 3.33568661 |
| 21 | Mediastinal lymphadenopathy (HP:0100721) | 3.24995905 |
| 22 | Hypochromic microcytic anemia (HP:0004840) | 3.22416289 |
| 23 | Keratoconjunctivitis sicca (HP:0001097) | 3.21067785 |
| 24 | Colitis (HP:0002583) | 3.16469498 |
| 25 | Pulmonary infiltrates (HP:0002113) | 3.15465844 |
| 26 | Tubulointerstitial nephritis (HP:0001970) | 3.15283473 |
| 27 | Fatigue (HP:0012378) | 3.13493837 |
| 28 | Obstructive lung disease (HP:0006536) | 3.09319136 |
| 29 | Chronic obstructive pulmonary disease (HP:0006510) | 3.09319136 |
| 30 | Amyloidosis (HP:0011034) | 3.04484900 |
| 31 | Hypochromic anemia (HP:0001931) | 3.00662591 |
| 32 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.00599777 |
| 33 | Inflammation of the large intestine (HP:0002037) | 3.00391672 |
| 34 | Abnormality of the nasal mucosa (HP:0000433) | 2.95754629 |
| 35 | Keratoconjunctivitis (HP:0001096) | 2.88966648 |
| 36 | Encephalitis (HP:0002383) | 2.87237273 |
| 37 | Gastrointestinal inflammation (HP:0004386) | 2.83345302 |
| 38 | Recurrent fungal infections (HP:0002841) | 2.82951827 |
| 39 | Gastrointestinal stroma tumor (HP:0100723) | 2.82617336 |
| 40 | Pustule (HP:0200039) | 2.81535287 |
| 41 | Agammaglobulinemia (HP:0004432) | 2.80625831 |
| 42 | Granulocytopenia (HP:0001913) | 2.75723616 |
| 43 | Gingival bleeding (HP:0000225) | 2.75166397 |
| 44 | Prolonged bleeding time (HP:0003010) | 2.74982978 |
| 45 | Autoimmune thrombocytopenia (HP:0001973) | 2.70230452 |
| 46 | Peritonitis (HP:0002586) | 2.68583512 |
| 47 | Recurrent viral infections (HP:0004429) | 2.66145614 |
| 48 | Leukocytosis (HP:0001974) | 2.63644774 |
| 49 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.63393074 |
| 50 | Epistaxis (HP:0000421) | 2.62970812 |
| 51 | Hypergammaglobulinemia (HP:0010702) | 2.61775300 |
| 52 | Increased IgM level (HP:0003496) | 2.60419159 |
| 53 | Abnormality of the peritoneum (HP:0002585) | 2.59156590 |
| 54 | Lymphopenia (HP:0001888) | 2.58184740 |
| 55 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.50739174 |
| 56 | Recurrent sinusitis (HP:0011108) | 2.50497505 |
| 57 | Increased cerebral lipofuscin (HP:0011813) | 2.49643424 |
| 58 | Recurrent skin infections (HP:0001581) | 2.49430232 |
| 59 | Urticaria (HP:0001025) | 2.48212327 |
| 60 | Gingivitis (HP:0000230) | 2.46558444 |
| 61 | Microcytic anemia (HP:0001935) | 2.45545003 |
| 62 | Hypertensive crisis (HP:0100735) | 2.45390733 |
| 63 | Emphysema (HP:0002097) | 2.44325366 |
| 64 | Chest pain (HP:0100749) | 2.42065033 |
| 65 | Abnormality of T cell physiology (HP:0011840) | 2.38331441 |
| 66 | Glomerulopathy (HP:0100820) | 2.37722368 |
| 67 | Episodic fever (HP:0001954) | 2.34637291 |
| 68 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.33851535 |
| 69 | Autoimmune hemolytic anemia (HP:0001890) | 2.26589328 |
| 70 | IgM deficiency (HP:0002850) | 2.24816355 |
| 71 | Osteomyelitis (HP:0002754) | 2.24411024 |
| 72 | Abnormality of T cells (HP:0002843) | 2.23804107 |
| 73 | Thoracic kyphosis (HP:0002942) | 2.20650885 |
| 74 | Reticulocytosis (HP:0001923) | 2.20055745 |
| 75 | Abnormality of the pleura (HP:0002103) | 2.19024464 |
| 76 | Hemoptysis (HP:0002105) | 2.18019795 |
| 77 | Increased serum ferritin (HP:0003281) | 2.17136227 |
| 78 | Acute hepatic failure (HP:0006554) | 2.14876266 |
| 79 | Arterial thrombosis (HP:0004420) | 2.12642723 |
| 80 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.12258417 |
| 81 | Recurrent cutaneous fungal infections (HP:0011370) | 2.12258417 |
| 82 | Recurrent pneumonia (HP:0006532) | 2.12211582 |
| 83 | Abnormality of B cell number (HP:0010975) | 2.11169783 |
| 84 | Interstitial pulmonary disease (HP:0006530) | 2.11023323 |
| 85 | Slow saccadic eye movements (HP:0000514) | 2.09241888 |
| 86 | Recurrent bronchitis (HP:0002837) | 2.07622538 |
| 87 | Recurrent lower respiratory tract infections (HP:0002783) | 2.07189018 |
| 88 | Skin rash (HP:0000988) | 2.06535173 |
| 89 | Polyneuropathy (HP:0001271) | 2.05911773 |
| 90 | Arthralgia (HP:0002829) | 2.04910847 |
| 91 | Chronic otitis media (HP:0000389) | 2.03954681 |
| 92 | Petechiae (HP:0000967) | 2.03940387 |
| 93 | Vertigo (HP:0002321) | 2.02549027 |
| 94 | Abnormality of iron homeostasis (HP:0011031) | 2.01491455 |
| 95 | Anorexia (HP:0002039) | 1.99767942 |
| 96 | Panhypogammaglobulinemia (HP:0003139) | 1.98947391 |
| 97 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.91308252 |
| 98 | Abnormality of the fingertips (HP:0001211) | 1.88475708 |
| 99 | Acne (HP:0001061) | 1.88373922 |
| 100 | Spontaneous hematomas (HP:0007420) | 1.87685091 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ERN1 | 4.11474242 |
| 2 | MAP4K1 | 3.72515990 |
| 3 | PRPF4B | 3.61654207 |
| 4 | MAP3K11 | 3.15560259 |
| 5 | RIPK4 | 3.08243779 |
| 6 | TAOK2 | 2.69588924 |
| 7 | TAOK3 | 2.53307016 |
| 8 | MAP2K3 | 2.42301596 |
| 9 | TNK2 | 2.22396489 |
| 10 | DDR2 | 2.20684383 |
| 11 | TESK1 | 2.14755984 |
| 12 | TBK1 | 2.14051874 |
| 13 | PLK4 | 1.92335734 |
| 14 | BLK | 1.91580526 |
| 15 | TYK2 | 1.90841137 |
| 16 | KIT | 1.83803236 |
| 17 | TAOK1 | 1.75094457 |
| 18 | TESK2 | 1.69678807 |
| 19 | JAK3 | 1.68302871 |
| 20 | IKBKE | 1.63430744 |
| 21 | ZAP70 | 1.58005025 |
| 22 | FLT3 | 1.55826387 |
| 23 | SIK2 | 1.53548626 |
| 24 | MAP3K13 | 1.51913084 |
| 25 | MAP3K1 | 1.50163058 |
| 26 | DYRK1B | 1.49821829 |
| 27 | MAP3K3 | 1.48855010 |
| 28 | IKBKB | 1.48498990 |
| 29 | CSF1R | 1.46487119 |
| 30 | SYK | 1.40616822 |
| 31 | FES | 1.37662254 |
| 32 | IRAK4 | 1.34803868 |
| 33 | MAP3K14 | 1.34221303 |
| 34 | STK38 | 1.29099289 |
| 35 | CSK | 1.24210825 |
| 36 | PTK2B | 1.19330774 |
| 37 | BMX | 1.17331264 |
| 38 | HCK | 1.14634597 |
| 39 | JAK1 | 1.13506668 |
| 40 | BTK | 1.13274285 |
| 41 | GRK7 | 1.12822544 |
| 42 | PRKG2 | 1.04217873 |
| 43 | PDK1 | 1.00257513 |
| 44 | JAK2 | 0.96223636 |
| 45 | KSR2 | 0.93482347 |
| 46 | PDPK1 | 0.92625675 |
| 47 | BRD4 | 0.91882577 |
| 48 | PRKD2 | 0.91286881 |
| 49 | RPS6KC1 | 0.90950596 |
| 50 | RPS6KL1 | 0.90950596 |
| 51 | EPHB1 | 0.88858788 |
| 52 | LYN | 0.88572493 |
| 53 | RPS6KA2 | 0.87691320 |
| 54 | SIK3 | 0.86176511 |
| 55 | HIPK2 | 0.85810608 |
| 56 | GRK6 | 0.84600895 |
| 57 | FGR | 0.84421809 |
| 58 | LCK | 0.82771687 |
| 59 | CDC42BPA | 0.81206239 |
| 60 | MATK | 0.79487682 |
| 61 | MAPK11 | 0.77875514 |
| 62 | CDK12 | 0.77687038 |
| 63 | MARK2 | 0.74673197 |
| 64 | PRKCQ | 0.74161632 |
| 65 | RPS6KA6 | 0.73083794 |
| 66 | MARK3 | 0.72336000 |
| 67 | TRIB3 | 0.71923231 |
| 68 | IRAK3 | 0.71549910 |
| 69 | SIK1 | 0.71044289 |
| 70 | CHUK | 0.70178284 |
| 71 | MAP2K2 | 0.67748168 |
| 72 | PIM1 | 0.67085303 |
| 73 | CDK4 | 0.63063982 |
| 74 | INSRR | 0.63048683 |
| 75 | MAP3K5 | 0.61863814 |
| 76 | ARAF | 0.61296835 |
| 77 | MOS | 0.57775368 |
| 78 | TXK | 0.54115436 |
| 79 | MAPK12 | 0.53116017 |
| 80 | MAP3K9 | 0.52670110 |
| 81 | MAP3K8 | 0.52146654 |
| 82 | PRKCH | 0.51124208 |
| 83 | CAMK1G | 0.48248941 |
| 84 | STK10 | 0.45856227 |
| 85 | BMPR2 | 0.44453724 |
| 86 | MAP3K7 | 0.44000618 |
| 87 | RPS6KA1 | 0.41180211 |
| 88 | MAPK7 | 0.40422249 |
| 89 | DMPK | 0.40403776 |
| 90 | PIK3CG | 0.38973150 |
| 91 | FYN | 0.34794978 |
| 92 | MAPK4 | 0.31602403 |
| 93 | KDR | 0.31096013 |
| 94 | MAPKAPK2 | 0.30954991 |
| 95 | IRAK1 | 0.29586733 |
| 96 | NME2 | 0.29406814 |
| 97 | ITK | 0.29377781 |
| 98 | BRAF | 0.29151955 |
| 99 | MTOR | 0.28483014 |
| 100 | NEK9 | 0.27704361 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Allograft rejection_Homo sapiens_hsa05330 | 3.61145717 |
| 2 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.30813461 |
| 3 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.25209912 |
| 4 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.69855886 |
| 5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.65199684 |
| 6 | Leishmaniasis_Homo sapiens_hsa05140 | 2.59750581 |
| 7 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.43539042 |
| 8 | Viral myocarditis_Homo sapiens_hsa05416 | 2.31645677 |
| 9 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.26574920 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.24480976 |
| 11 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.15495482 |
| 12 | Asthma_Homo sapiens_hsa05310 | 2.12718988 |
| 13 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.02128052 |
| 14 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.99851847 |
| 15 | Influenza A_Homo sapiens_hsa05164 | 1.98936129 |
| 16 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.95413692 |
| 17 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.90649612 |
| 18 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.87167995 |
| 19 | Measles_Homo sapiens_hsa05162 | 1.82400743 |
| 20 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.81972513 |
| 21 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.75668874 |
| 22 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.75590037 |
| 23 | Tuberculosis_Homo sapiens_hsa05152 | 1.67704637 |
| 24 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.67037345 |
| 25 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.60716498 |
| 26 | Malaria_Homo sapiens_hsa05144 | 1.48924847 |
| 27 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.43678394 |
| 28 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.43656691 |
| 29 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.42160115 |
| 30 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.41105094 |
| 31 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.40741635 |
| 32 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.39607806 |
| 33 | Other glycan degradation_Homo sapiens_hsa00511 | 1.34126243 |
| 34 | Hepatitis C_Homo sapiens_hsa05160 | 1.22870006 |
| 35 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.22331692 |
| 36 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.13125527 |
| 37 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.12012663 |
| 38 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.08833200 |
| 39 | Legionellosis_Homo sapiens_hsa05134 | 1.07651527 |
| 40 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.06511141 |
| 41 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.06285980 |
| 42 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.04938001 |
| 43 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.04624769 |
| 44 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.03493027 |
| 45 | Apoptosis_Homo sapiens_hsa04210 | 1.01642686 |
| 46 | Hepatitis B_Homo sapiens_hsa05161 | 1.00978816 |
| 47 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.99997559 |
| 48 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.97051121 |
| 49 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.94898892 |
| 50 | Phagosome_Homo sapiens_hsa04145 | 0.92547352 |
| 51 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.92149459 |
| 52 | Platelet activation_Homo sapiens_hsa04611 | 0.91046182 |
| 53 | Pertussis_Homo sapiens_hsa05133 | 0.87950853 |
| 54 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.80602764 |
| 55 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.78183893 |
| 56 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.76466471 |
| 57 | Endocytosis_Homo sapiens_hsa04144 | 0.75692423 |
| 58 | Bladder cancer_Homo sapiens_hsa05219 | 0.71109893 |
| 59 | Shigellosis_Homo sapiens_hsa05131 | 0.70450783 |
| 60 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.69550378 |
| 61 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.68156365 |
| 62 | Salmonella infection_Homo sapiens_hsa05132 | 0.68031191 |
| 63 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.67443031 |
| 64 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.67276351 |
| 65 | HTLV-I infection_Homo sapiens_hsa05166 | 0.67080727 |
| 66 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.65228708 |
| 67 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.63687543 |
| 68 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.63404352 |
| 69 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.61312796 |
| 70 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.59738414 |
| 71 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.59204242 |
| 72 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.52480530 |
| 73 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.50857932 |
| 74 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.50684029 |
| 75 | Insulin resistance_Homo sapiens_hsa04931 | 0.49785244 |
| 76 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.49433544 |
| 77 | Amoebiasis_Homo sapiens_hsa05146 | 0.48022742 |
| 78 | Olfactory transduction_Homo sapiens_hsa04740 | 0.47309868 |
| 79 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.44548346 |
| 80 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.44144443 |
| 81 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.43803996 |
| 82 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.42391438 |
| 83 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.42270005 |
| 84 | Lysosome_Homo sapiens_hsa04142 | 0.41790187 |
| 85 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.41123328 |
| 86 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.40328408 |
| 87 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.39578393 |
| 88 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.35871927 |
| 89 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.33505028 |
| 90 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.32061303 |
| 91 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.29662649 |
| 92 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.29636096 |
| 93 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.28784433 |
| 94 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.27866510 |
| 95 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.27794165 |
| 96 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.26339430 |
| 97 | Prion diseases_Homo sapiens_hsa05020 | 0.25179035 |
| 98 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.22932324 |
| 99 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.21654926 |
| 100 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.18711365 |

