TBRG4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1folic acid-containing compound biosynthetic process (GO:0009396)4.63279978
2IMP biosynthetic process (GO:0006188)4.50328506
3DNA replication initiation (GO:0006270)4.50190579
4DNA strand elongation involved in DNA replication (GO:0006271)4.42971391
5nucleobase biosynthetic process (GO:0046112)4.36197911
6DNA unwinding involved in DNA replication (GO:0006268)4.36071281
7DNA strand elongation (GO:0022616)4.23918054
8telomere maintenance via semi-conservative replication (GO:0032201)4.15541056
9ribosome biogenesis (GO:0042254)4.02834348
10nuclear pore organization (GO:0006999)3.99973302
11mitotic chromosome condensation (GO:0007076)3.96392267
12mitotic nuclear envelope disassembly (GO:0007077)3.91385790
13formation of translation preinitiation complex (GO:0001731)3.91189563
14DNA replication-dependent nucleosome assembly (GO:0006335)3.90805727
15DNA replication-dependent nucleosome organization (GO:0034723)3.90805727
16maturation of SSU-rRNA (GO:0030490)3.90495033
17nuclear pore complex assembly (GO:0051292)3.83702516
18DNA deamination (GO:0045006)3.83356291
19protein localization to kinetochore (GO:0034501)3.82374081
20IMP metabolic process (GO:0046040)3.82036969
21purine nucleobase biosynthetic process (GO:0009113)3.81495955
22DNA replication checkpoint (GO:0000076)3.79305422
23ribosome assembly (GO:0042255)3.78723524
24proline biosynthetic process (GO:0006561)3.76469485
25ribosomal large subunit biogenesis (GO:0042273)3.74261901
26viral mRNA export from host cell nucleus (GO:0046784)3.72142869
27ribonucleoprotein complex biogenesis (GO:0022613)3.68982153
28protein complex localization (GO:0031503)3.60712999
29regulation of gene silencing by RNA (GO:0060966)3.58606992
30regulation of posttranscriptional gene silencing (GO:0060147)3.58606992
31regulation of gene silencing by miRNA (GO:0060964)3.58606992
32telomere maintenance via recombination (GO:0000722)3.56489872
33membrane disassembly (GO:0030397)3.54619778
34nuclear envelope disassembly (GO:0051081)3.54619778
35establishment of integrated proviral latency (GO:0075713)3.49553430
36telomere maintenance via telomere lengthening (GO:0010833)3.41252178
37proteasome assembly (GO:0043248)3.39830902
38cellular protein complex localization (GO:0034629)3.39667521
39Golgi transport vesicle coating (GO:0048200)3.38967716
40COPI coating of Golgi vesicle (GO:0048205)3.38967716
41mitotic metaphase plate congression (GO:0007080)3.38943317
42regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.38752641
43regulation of nuclear cell cycle DNA replication (GO:0033262)3.35984946
44folic acid metabolic process (GO:0046655)3.34713564
45mitotic recombination (GO:0006312)3.34230674
46protein localization to chromosome, centromeric region (GO:0071459)3.33346842
47nucleobase-containing small molecule interconversion (GO:0015949)3.33127268
48ribosomal small subunit assembly (GO:0000028)3.31855210
49rRNA processing (GO:0006364)3.31138720
50DNA duplex unwinding (GO:0032508)3.28904289
51DNA geometric change (GO:0032392)3.27620050
52heterochromatin organization (GO:0070828)3.27173905
53L-serine metabolic process (GO:0006563)3.25843633
54regulation of mammary gland epithelial cell proliferation (GO:0033599)3.24530510
55mitochondrial RNA metabolic process (GO:0000959)3.23567755
56rRNA metabolic process (GO:0016072)3.22546953
57regulation of translational fidelity (GO:0006450)3.22259131
58rRNA transcription (GO:0009303)3.20543618
59spliceosomal snRNP assembly (GO:0000387)3.18282870
60negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.17561108
61mitotic sister chromatid segregation (GO:0000070)3.16712751
62negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.16694779
63pentose-phosphate shunt (GO:0006098)3.15720235
64nucleotide-excision repair, DNA gap filling (GO:0006297)3.14070292
65regulation of mitochondrial translation (GO:0070129)3.11863804
66somatic hypermutation of immunoglobulin genes (GO:0016446)3.11728226
67somatic diversification of immune receptors via somatic mutation (GO:0002566)3.11728226
68anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.10339624
69tetrahydrofolate metabolic process (GO:0046653)3.09018435
70rRNA modification (GO:0000154)3.08415073
71ribosomal small subunit biogenesis (GO:0042274)3.06256812
72viral transcription (GO:0019083)3.06242299
73regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.05238188
74spliceosomal tri-snRNP complex assembly (GO:0000244)3.03532206
75NADPH regeneration (GO:0006740)3.02709866
76tricarboxylic acid cycle (GO:0006099)3.02111875
77negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.00701292
78negative regulation of ligase activity (GO:0051352)3.00701292
79transcription from mitochondrial promoter (GO:0006390)3.00518178
80pteridine-containing compound biosynthetic process (GO:0042559)3.00481966
81translational termination (GO:0006415)3.00088299
82protein maturation by protein folding (GO:0022417)2.99614933
83translational initiation (GO:0006413)2.99224743
84mitochondrial DNA metabolic process (GO:0032042)2.97453673
85maturation of 5.8S rRNA (GO:0000460)2.95720089
86pore complex assembly (GO:0046931)2.94602539
87kinetochore organization (GO:0051383)2.93040949
88pseudouridine synthesis (GO:0001522)2.91775932
89kinetochore assembly (GO:0051382)2.91359607
90positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.91139637
91nuclear envelope reassembly (GO:0031468)2.90939926
92mitotic nuclear envelope reassembly (GO:0007084)2.90939926
93GDP-mannose metabolic process (GO:0019673)2.90651302
94establishment of viral latency (GO:0019043)2.90536221
95protein K6-linked ubiquitination (GO:0085020)2.90092401
96translational elongation (GO:0006414)2.87606060
97peptidyl-arginine methylation (GO:0018216)2.86950510
98peptidyl-arginine N-methylation (GO:0035246)2.86950510
99chromatin remodeling at centromere (GO:0031055)2.86491490
100regulation of spindle organization (GO:0090224)2.86465155
101regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.85307697
102regulation of mitotic spindle organization (GO:0060236)2.83827533
103negative regulation of mRNA processing (GO:0050686)2.83659210
104tRNA aminoacylation for protein translation (GO:0006418)2.83563012
105metaphase plate congression (GO:0051310)2.83441547
106folic acid-containing compound metabolic process (GO:0006760)2.83090530
107glycine metabolic process (GO:0006544)2.83089252
108pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.81926827
109regulation of histone H3-K9 methylation (GO:0051570)2.81898587
110maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.81099305
111mitochondrial DNA replication (GO:0006264)2.79922273
112snRNA metabolic process (GO:0016073)2.79798741
113DNA topological change (GO:0006265)2.79749127
114pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.79603193
115peptidyl-arginine omega-N-methylation (GO:0035247)2.79575346
116negative regulation of RNA splicing (GO:0033119)2.78647076
117histone arginine methylation (GO:0034969)2.78468196
118histone H4-K12 acetylation (GO:0043983)2.78389531
119positive regulation of chromosome segregation (GO:0051984)2.78089406
120pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.77789440
121dosage compensation (GO:0007549)2.77656919
122CENP-A containing nucleosome assembly (GO:0034080)2.76229643
123regulation of double-strand break repair via homologous recombination (GO:0010569)2.74596239
124nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.74386523
125amino acid activation (GO:0043038)2.73623158
126tRNA aminoacylation (GO:0043039)2.73623158
127regulation of translation in response to stress (GO:0043555)2.73431427
128regulation of translational elongation (GO:0006448)2.73215830
129tRNA methylation (GO:0030488)2.72894149
130sister chromatid segregation (GO:0000819)2.72601246
131nuclear envelope organization (GO:0006998)2.70279531
132DNA replication (GO:0006260)2.69572398
133base-excision repair (GO:0006284)2.68892028
134telomere organization (GO:0032200)2.67895685
135mitochondrial fusion (GO:0008053)2.67641827
136regulation of translational termination (GO:0006449)2.66825905
137regulation of gene silencing (GO:0060968)2.66651595
138regulation of helicase activity (GO:0051095)2.66638316
139negative regulation of chromosome segregation (GO:0051985)2.66517660
140telomere maintenance (GO:0000723)2.66107346
141DNA replication-independent nucleosome organization (GO:0034724)2.64939866
142DNA replication-independent nucleosome assembly (GO:0006336)2.64939866
143positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.64094002
144DNA conformation change (GO:0071103)2.62933848
145signal transduction involved in DNA integrity checkpoint (GO:0072401)2.61808631

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.04440716
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.11101697
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.64781457
4* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.53380260
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.22799687
6* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.01327187
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.84949805
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.76833914
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.75048971
10* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.49325854
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.49048289
12* ETS1_20019798_ChIP-Seq_JURKAT_Human2.44514326
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.40940506
14NELFA_20434984_ChIP-Seq_ESCs_Mouse2.16591089
15XRN2_22483619_ChIP-Seq_HELA_Human2.13788549
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.07746556
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.05200537
18MYC_22102868_ChIP-Seq_BL_Human2.03421062
19GABP_17652178_ChIP-ChIP_JURKAT_Human2.02522484
20MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.96519528
21SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.93216164
22* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.90250007
23NANOG_18555785_ChIP-Seq_MESCs_Mouse1.89109346
24ZNF263_19887448_ChIP-Seq_K562_Human1.87836220
25CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.84335246
26* VDR_23849224_ChIP-Seq_CD4+_Human1.83779472
27NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.83732935
28ELF1_17652178_ChIP-ChIP_JURKAT_Human1.80355456
29E2F1_18555785_ChIP-Seq_MESCs_Mouse1.78901835
30FOXP3_21729870_ChIP-Seq_TREG_Human1.78002247
31* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.77544156
32CIITA_25753668_ChIP-Seq_RAJI_Human1.75755421
33EGR1_19374776_ChIP-ChIP_THP-1_Human1.74212102
34E2F1_21310950_ChIP-Seq_MCF-7_Human1.74195052
35* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.73615433
36THAP11_20581084_ChIP-Seq_MESCs_Mouse1.70142825
37YY1_21170310_ChIP-Seq_MESCs_Mouse1.68143767
38* DCP1A_22483619_ChIP-Seq_HELA_Human1.68030097
39STAT3_1855785_ChIP-Seq_MESCs_Mouse1.66882631
40E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.65700937
41PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.61891580
42POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.59520793
43TTF2_22483619_ChIP-Seq_HELA_Human1.57660888
44* GABP_19822575_ChIP-Seq_HepG2_Human1.57500307
45* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.54744523
46AR_21909140_ChIP-Seq_LNCAP_Human1.51815872
47* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.50564894
48TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.49158873
49KDM5A_27292631_Chip-Seq_BREAST_Human1.45347795
50* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.42936585
51* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.40052348
52VDR_21846776_ChIP-Seq_THP-1_Human1.38191560
53PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.36969255
54HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.36562070
55PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.33656516
56CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.33181009
57TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32498554
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.30606056
59* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.29925146
60CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.29279413
61TP63_19390658_ChIP-ChIP_HaCaT_Human1.22941324
62MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.21591761
63* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.21584742
64TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.21505778
65SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.20488479
66NOTCH1_21737748_ChIP-Seq_TLL_Human1.20464137
67SRF_21415370_ChIP-Seq_HL-1_Mouse1.19196266
68ESR1_15608294_ChIP-ChIP_MCF-7_Human1.18499364
69KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.17083680
70* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.15672857
71* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.14167941
72HOXB4_20404135_ChIP-ChIP_EML_Mouse1.12525988
73* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.11801229
74KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.11772762
75KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.11772762
76KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.11772762
77NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.10867377
78RACK7_27058665_Chip-Seq_MCF-7_Human1.10570820
79ELK3_25401928_ChIP-Seq_HUVEC_Human1.10565119
80* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.10418181
81ELK1_19687146_ChIP-ChIP_HELA_Human1.08243874
82KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.07491722
83ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.07367711
84NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.06489214
85TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06031047
86DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.05864959
87SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.04110661
88TFEB_21752829_ChIP-Seq_HELA_Human1.03917650
89SOX2_18555785_ChIP-Seq_MESCs_Mouse1.03822646
90LXR_22292898_ChIP-Seq_THP-1_Human1.03036031
91TET1_21451524_ChIP-Seq_MESCs_Mouse1.02985366
92SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.01838555
93NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.01499162
94TCF3_18692474_ChIP-Seq_MEFs_Mouse1.01382519
95* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.01188167
96ATF3_27146783_Chip-Seq_COLON_Human1.00574383
97SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.99968323
98* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.99274852
99SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.99096386
100FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.98640849
101KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.97176353
102* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.97141349
103TBX5_21415370_ChIP-Seq_HL-1_Mouse0.96948433
104NCOR1_26117541_ChIP-Seq_K562_Human0.95944736
105E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.95162631
106CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.94395828
107GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.92855856
108CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.92525423
109SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.91049495
110PADI4_21655091_ChIP-ChIP_MCF-7_Human0.89781186
111ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.88679156
112* NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.88454685
113HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.87506089
114* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.86379060
115CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.85957667
116OCT4_18692474_ChIP-Seq_MEFs_Mouse0.85250777
117TCF3_18692474_ChIP-Seq_MESCs_Mouse0.85059530
118ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.83367434
119CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.82876814
120POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.82501851
121SOX2_18692474_ChIP-Seq_MEFs_Mouse0.81783504
122* NANOG_21062744_ChIP-ChIP_HESCs_Human0.80833568

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.78056690
2MP0003111_abnormal_nucleus_morphology4.45629803
3MP0010094_abnormal_chromosome_stability4.11793341
4MP0008057_abnormal_DNA_replication3.96328458
5MP0004957_abnormal_blastocyst_morpholog3.72713773
6MP0003077_abnormal_cell_cycle3.52144676
7MP0008058_abnormal_DNA_repair2.97095545
8MP0003806_abnormal_nucleotide_metabolis2.53281060
9MP0004233_abnormal_muscle_weight2.47770242
10MP0002396_abnormal_hematopoietic_system2.38125929
11MP0001730_embryonic_growth_arrest2.18730429
12MP0008932_abnormal_embryonic_tissue2.13137726
13MP0010352_gastrointestinal_tract_polyps2.10948769
14MP0008260_abnormal_autophagy2.10489123
15MP0008007_abnormal_cellular_replicative2.08699817
16MP0003786_premature_aging2.04832293
17MP0000350_abnormal_cell_proliferation2.04384772
18MP0001672_abnormal_embryogenesis/_devel1.90006697
19MP0005380_embryogenesis_phenotype1.90006697
20MP0010234_abnormal_vibrissa_follicle1.86484674
21MP0010307_abnormal_tumor_latency1.84441694
22MP0000490_abnormal_crypts_of1.82154243
23MP0003984_embryonic_growth_retardation1.76205491
24MP0002088_abnormal_embryonic_growth/wei1.72062874
25MP0001661_extended_life_span1.70713659
26MP0002877_abnormal_melanocyte_morpholog1.64126826
27MP0002796_impaired_skin_barrier1.58701702
28MP0001697_abnormal_embryo_size1.56390602
29MP0008877_abnormal_DNA_methylation1.54855104
30MP0003718_maternal_effect1.51637613
31MP0002080_prenatal_lethality1.51191534
32MP0005058_abnormal_lysosome_morphology1.46333896
33MP0004197_abnormal_fetal_growth/weight/1.46130293
34MP0002085_abnormal_embryonic_tissue1.45611475
35MP0000313_abnormal_cell_death1.44060814
36MP0002086_abnormal_extraembryonic_tissu1.43254086
37MP0009697_abnormal_copulation1.42421175
38MP0003567_abnormal_fetal_cardiomyocyte1.42245185
39MP0009333_abnormal_splenocyte_physiolog1.38886432
40MP0000678_abnormal_parathyroid_gland1.34736687
41MP0002019_abnormal_tumor_incidence1.33625629
42MP0002084_abnormal_developmental_patter1.28865764
43MP0005076_abnormal_cell_differentiation1.26861859
44MP0003123_paternal_imprinting1.26162597
45MP0004808_abnormal_hematopoietic_stem1.25524329
46MP0005083_abnormal_biliary_tract1.25330928
47MP0004133_heterotaxia1.23935069
48MP0000537_abnormal_urethra_morphology1.23357975
49MP0001849_ear_inflammation1.16211108
50MP0001873_stomach_inflammation1.16137377
51MP0003646_muscle_fatigue1.14946241
52MP0005670_abnormal_white_adipose1.14186589
53MP0003941_abnormal_skin_development1.13888811
54MP0003890_abnormal_embryonic-extraembry1.13486331
55MP0003763_abnormal_thymus_physiology1.12812060
56MP0000750_abnormal_muscle_regeneration1.12525329
57MP0000703_abnormal_thymus_morphology1.10263610
58MP0001293_anophthalmia1.10172354
59MP0002722_abnormal_immune_system1.09833054
60MP0000689_abnormal_spleen_morphology1.08403814
61MP0001545_abnormal_hematopoietic_system1.06003794
62MP0005397_hematopoietic_system_phenotyp1.06003794
63MP0009840_abnormal_foam_cell1.03638569
64MP0009672_abnormal_birth_weight1.03364138
65MP0003566_abnormal_cell_adhesion1.03350569
66MP0003453_abnormal_keratinocyte_physiol1.03011217
67MP0002398_abnormal_bone_marrow1.02374696
68MP0002254_reproductive_system_inflammat1.01871524
69MP0002060_abnormal_skin_morphology1.01819439
70MP0010030_abnormal_orbit_morphology1.01259064
71MP0000747_muscle_weakness0.98771562
72MP0001216_abnormal_epidermal_layer0.98579168
73MP0003656_abnormal_erythrocyte_physiolo0.95927543
74MP0002132_abnormal_respiratory_system0.95744422
75MP0009278_abnormal_bone_marrow0.94597232
76MP0002269_muscular_atrophy0.93564153
77MP0003186_abnormal_redox_activity0.93371618
78MP0003119_abnormal_digestive_system0.92630138
79MP0006036_abnormal_mitochondrial_physio0.92392160
80MP0006035_abnormal_mitochondrial_morpho0.91625466
81MP0004264_abnormal_extraembryonic_tissu0.91451612
82MP0005266_abnormal_metabolism0.91106069
83MP0002089_abnormal_postnatal_growth/wei0.90672221
84MP0002210_abnormal_sex_determination0.90052224
85MP0006292_abnormal_olfactory_placode0.89276283
86MP0008995_early_reproductive_senescence0.88673805
87MP0005408_hypopigmentation0.86955672
88MP0000372_irregular_coat_pigmentation0.85510963
89MP0000358_abnormal_cell_content/0.84951166
90MP0002653_abnormal_ependyma_morphology0.83978842
91MP0003221_abnormal_cardiomyocyte_apopto0.83895742
92MP0010630_abnormal_cardiac_muscle0.83036545
93MP0002429_abnormal_blood_cell0.82627190
94MP0009931_abnormal_skin_appearance0.82486569
95MP0001348_abnormal_lacrimal_gland0.82404402
96MP0001145_abnormal_male_reproductive0.82357581
97MP0000858_altered_metastatic_potential0.81103926
98MP0003705_abnormal_hypodermis_morpholog0.80997159
99MP0000003_abnormal_adipose_tissue0.79419169
100MP0002111_abnormal_tail_morphology0.79163514
101MP0004381_abnormal_hair_follicle0.78956867
102MP0005384_cellular_phenotype0.77278152
103MP0005330_cardiomyopathy0.74603886
104MP0005075_abnormal_melanosome_morpholog0.74553666
105MP0004084_abnormal_cardiac_muscle0.74450513
106MP0003315_abnormal_perineum_morphology0.73925304
107MP0005621_abnormal_cell_physiology0.72841492
108MP0000477_abnormal_intestine_morphology0.72676229
109MP0000759_abnormal_skeletal_muscle0.72188148
110MP0009053_abnormal_anal_canal0.71730071
111MP0003828_pulmonary_edema0.71392119
112MP0001853_heart_inflammation0.71271565
113MP0005171_absent_coat_pigmentation0.70265297
114MP0001346_abnormal_lacrimal_gland0.69967168
115MP0005023_abnormal_wound_healing0.69838574
116MP0001727_abnormal_embryo_implantation0.69072199
117MP0001800_abnormal_humoral_immune0.68333087
118MP0000751_myopathy0.68185774
119MP0003191_abnormal_cellular_cholesterol0.68025002
120MP0000749_muscle_degeneration0.67979110
121MP0002160_abnormal_reproductive_system0.67946670
122MP0005451_abnormal_body_composition0.67915415
123MP0000716_abnormal_immune_system0.67079771
124MP0000733_abnormal_muscle_development0.66981389
125MP0002970_abnormal_white_adipose0.66851231
126MP0009703_decreased_birth_body0.66511323
127MP0001243_abnormal_dermal_layer0.66090342
128MP0001881_abnormal_mammary_gland0.66037551
129MP0004782_abnormal_surfactant_physiolog0.64772031
130MP0004147_increased_porphyrin_level0.64311817
131MP0001929_abnormal_gametogenesis0.64192686
132MP0001915_intracranial_hemorrhage0.62899155
133MP0000653_abnormal_sex_gland0.61801707
134MP0002405_respiratory_system_inflammati0.61621790
135MP0003121_genomic_imprinting0.61523194
136MP0000371_diluted_coat_color0.61462915
137MP0005666_abnormal_adipose_tissue0.60129623
138MP0000598_abnormal_liver_morphology0.60044108
139MP0005501_abnormal_skin_physiology0.59866918
140MP0000266_abnormal_heart_morphology0.59793871
141MP0004185_abnormal_adipocyte_glucose0.58992366

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.78671800
2Chromsome breakage (HP:0040012)4.57819627
3Birth length less than 3rd percentile (HP:0003561)4.12224027
4Cholecystitis (HP:0001082)4.04452447
5Abnormal gallbladder physiology (HP:0012438)4.04452447
6Reticulocytopenia (HP:0001896)3.99292571
7Abnormality of glycolysis (HP:0004366)3.83852146
8Ragged-red muscle fibers (HP:0003200)3.67400947
9Breast hypoplasia (HP:0003187)3.53097076
10Ependymoma (HP:0002888)3.42679123
11Abnormality of pyrimidine metabolism (HP:0004353)3.24434077
12Increased serum pyruvate (HP:0003542)3.18969537
13Selective tooth agenesis (HP:0001592)3.15836932
14Abnormality of the preputium (HP:0100587)3.13329182
15Abnormality of chromosome stability (HP:0003220)3.09787079
16Duplicated collecting system (HP:0000081)3.09371243
17Meckel diverticulum (HP:0002245)3.07705094
18Abnormality of cells of the erythroid lineage (HP:0012130)3.05506652
19Oral leukoplakia (HP:0002745)3.04279179
20Abnormality of the ileum (HP:0001549)3.00830489
21Absent thumb (HP:0009777)2.98495134
22Aplasia/Hypoplasia of the uvula (HP:0010293)2.96174121
23Impulsivity (HP:0100710)2.95947259
24Patellar aplasia (HP:0006443)2.94486714
25Abnormal number of erythroid precursors (HP:0012131)2.93732548
26Medulloblastoma (HP:0002885)2.82349108
27Carpal bone hypoplasia (HP:0001498)2.81330728
28Aplasia/Hypoplasia of the patella (HP:0006498)2.71959791
29Absent radius (HP:0003974)2.68991040
30Abnormality of the renal collecting system (HP:0004742)2.63748548
31Agnosia (HP:0010524)2.61188417
32Rough bone trabeculation (HP:0100670)2.59814411
33Bone marrow hypocellularity (HP:0005528)2.58448920
34Myelodysplasia (HP:0002863)2.53049853
35Absent forearm bone (HP:0003953)2.48283676
36Aplasia involving forearm bones (HP:0009822)2.48283676
37Macrocytic anemia (HP:0001972)2.48093278
38Abnormal number of incisors (HP:0011064)2.46497451
39Multiple enchondromatosis (HP:0005701)2.44364974
40Hyperacusis (HP:0010780)2.40527477
41Abnormality of reticulocytes (HP:0004312)2.38807327
42Ectopic kidney (HP:0000086)2.36917265
43Increased serum lactate (HP:0002151)2.32011975
44Abnormality of the labia minora (HP:0012880)2.31541445
45Abnormality of the anterior horn cell (HP:0006802)2.30769375
46Degeneration of anterior horn cells (HP:0002398)2.30769375
47Entropion (HP:0000621)2.30676013
48Small intestinal stenosis (HP:0012848)2.29341753
49Duodenal stenosis (HP:0100867)2.29341753
50Trismus (HP:0000211)2.27621215
51Pallor (HP:0000980)2.25811640
52Squamous cell carcinoma (HP:0002860)2.24033947
53Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.23861294
54Myopathic facies (HP:0002058)2.23846188
55Ureteral duplication (HP:0000073)2.23450105
56Rhabdomyosarcoma (HP:0002859)2.23310304
57Tracheoesophageal fistula (HP:0002575)2.23141901
58Increased intramyocellular lipid droplets (HP:0012240)2.20448687
59Progressive muscle weakness (HP:0003323)2.19753323
60Poikiloderma (HP:0001029)2.19318205
61Premature ovarian failure (HP:0008209)2.18692558
62Type I transferrin isoform profile (HP:0003642)2.18583267
63Abnormality of the umbilical cord (HP:0010881)2.17706703
64Rhabdomyolysis (HP:0003201)2.17480466
65Neoplasm of the pancreas (HP:0002894)2.13047472
66Abnormality of the carotid arteries (HP:0005344)2.11960522
67Centrally nucleated skeletal muscle fibers (HP:0003687)2.10956274
68Cerebral hypomyelination (HP:0006808)2.10432234
69Aplastic anemia (HP:0001915)2.10114730
70Cholelithiasis (HP:0001081)2.09069151
71Sloping forehead (HP:0000340)2.08781517
72Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.08744899
73Horseshoe kidney (HP:0000085)2.08720776
74Hepatocellular necrosis (HP:0001404)2.08153398
75Short thumb (HP:0009778)2.06759085
76Basal cell carcinoma (HP:0002671)2.05439205
77Reticulocytosis (HP:0001923)2.03852390
78Exercise intolerance (HP:0003546)2.03742737
79Colon cancer (HP:0003003)2.03741453
80Premature graying of hair (HP:0002216)2.02502396
81Reduced antithrombin III activity (HP:0001976)2.02373216
82Glioma (HP:0009733)2.01669993
83Insomnia (HP:0100785)2.01479369
84Rib fusion (HP:0000902)2.00483968
85Amaurosis fugax (HP:0100576)2.00265474
86Abnormality of DNA repair (HP:0003254)1.99348377
87Clubbing of toes (HP:0100760)1.98927238
88Nausea (HP:0002018)1.98878260
89Increased muscle lipid content (HP:0009058)1.98806148
90Cellular immunodeficiency (HP:0005374)1.98383935
91Truncus arteriosus (HP:0001660)1.96237652
92Abnormality of the duodenum (HP:0002246)1.96193571
93Ventricular tachycardia (HP:0004756)1.94894024
94Abnormalities of placenta or umbilical cord (HP:0001194)1.93338052
95Abnormal mitochondria in muscle tissue (HP:0008316)1.92886673
96Triphalangeal thumb (HP:0001199)1.92691724
97Abnormality of the astrocytes (HP:0100707)1.92606351
98Astrocytoma (HP:0009592)1.92606351
99Cafe-au-lait spot (HP:0000957)1.92016725
100Microretrognathia (HP:0000308)1.91633698
101Testicular atrophy (HP:0000029)1.89049300
102Abnormal trabecular bone morphology (HP:0100671)1.88210354
103Abnormality of abdominal situs (HP:0011620)1.87218396
104Abdominal situs inversus (HP:0003363)1.87218396
105Hypokinesia (HP:0002375)1.87059950
106Abnormality of methionine metabolism (HP:0010901)1.86957016
107Lactic acidosis (HP:0003128)1.85723994
108Megaloblastic anemia (HP:0001889)1.85566399
109Distal lower limb muscle weakness (HP:0009053)1.85301113
110Increased connective tissue (HP:0009025)1.84537075
111Microvesicular hepatic steatosis (HP:0001414)1.83463845
112Neoplasm of striated muscle (HP:0009728)1.83252116
113Distal lower limb amyotrophy (HP:0008944)1.82653749
114Lymphoma (HP:0002665)1.82557787
115Achilles tendon contracture (HP:0001771)1.82383497
116Hepatic necrosis (HP:0002605)1.82144451
117Hypertensive crisis (HP:0100735)1.82052261
118Aplasia/hypoplasia of the humerus (HP:0006507)1.80560289
119Abnormal umbilical cord blood vessels (HP:0011403)1.80209667
120Single umbilical artery (HP:0001195)1.80209667
121Abnormality of the fetal cardiovascular system (HP:0010948)1.80209667
122Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.80204699
123Abnormal protein N-linked glycosylation (HP:0012347)1.80204699
124Abnormal protein glycosylation (HP:0012346)1.80204699
125Abnormal glycosylation (HP:0012345)1.80204699
126Prominent nose (HP:0000448)1.80098940
127Anal stenosis (HP:0002025)1.78200066
12811 pairs of ribs (HP:0000878)1.78169352
129Pancytopenia (HP:0001876)1.75827497
130Progressive external ophthalmoplegia (HP:0000590)1.75486438
131Supernumerary bones of the axial skeleton (HP:0009144)1.75434333
132Aplasia/Hypoplasia of the sacrum (HP:0008517)1.75368028
133Leukopenia (HP:0001882)1.75233840
134Increased nuchal translucency (HP:0010880)1.74949714
135Abnormality of the distal phalanges of the toes (HP:0010182)1.74667597
136Hypergonadotropic hypogonadism (HP:0000815)1.74303063
137Abnormal gallbladder morphology (HP:0012437)1.73196177
138Increased CSF lactate (HP:0002490)1.73114147
139Seborrheic dermatitis (HP:0001051)1.72916378
140Septate vagina (HP:0001153)1.71518254
141Intestinal fistula (HP:0100819)1.70968329
142Proximal placement of thumb (HP:0009623)1.69576470
143Abnormality of subcutaneous fat tissue (HP:0001001)1.69459933
144Decreased activity of mitochondrial respiratory chain (HP:0008972)1.68143415
145Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.68143415
146Hyperglycinuria (HP:0003108)1.68007794
147Abnormal hair laboratory examination (HP:0003328)1.67164919
148IgM deficiency (HP:0002850)1.66705597
149Impaired proprioception (HP:0010831)1.65810273
150Breech presentation (HP:0001623)1.65010326
151Spastic paraparesis (HP:0002313)1.64594083
152Abnormality of the gallbladder (HP:0005264)1.64578552
153Secondary amenorrhea (HP:0000869)1.64316145
154Shoulder girdle muscle weakness (HP:0003547)1.63265090
155Deviation of the thumb (HP:0009603)1.63070455
156Acute encephalopathy (HP:0006846)1.62952205
157Neoplasm of head and neck (HP:0012288)1.62428627
158Esophageal neoplasm (HP:0100751)1.62428627
159Upper limb muscle weakness (HP:0003484)1.59558087
160Ileus (HP:0002595)1.59024516

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SMG13.57668661
2BUB13.45628414
3CDK123.12482993
4CDC73.10626098
5WEE13.06514399
6ZAK2.82794671
7PBK2.76536436
8EPHA22.75905444
9VRK22.49919713
10EEF2K2.38298766
11TTK2.38001910
12TLK12.37663577
13NEK22.25134604
14NME22.16339370
15EIF2AK12.12668245
16TSSK62.02985319
17NEK12.01757396
18SRPK11.98247934
19PLK41.97764288
20CDK71.91376929
21PDK21.85010015
22MST1R1.82214548
23RPS6KB21.79873437
24IRAK31.74762856
25PLK11.70455397
26CDK41.67709309
27ATR1.66401673
28SCYL21.66256127
29NME11.58122725
30MAP3K101.52724742
31MAP4K11.52555556
32BRD41.52443693
33STK41.48943559
34VRK11.45034615
35STK161.44572695
36PKN21.43572283
37FLT31.39420882
38CHEK21.38451015
39TESK21.37444222
40AURKB1.36501349
41MAP3K81.35902442
42PASK1.26550840
43CHEK11.25004673
44MKNK21.24617588
45STK101.22598066
46PIM11.21373139
47PRPF4B1.20399529
48EIF2AK31.17491522
49ACVR1B1.17081702
50MKNK11.15338358
51CDK81.15171099
52MAP2K31.15115640
53TTN1.11976512
54AURKA1.11491701
55DYRK31.09606571
56BCKDK1.08393691
57ALK1.07787883
58SIK11.07336909
59STK38L1.05990190
60BRSK20.98767199
61PAK40.94436424
62TAF10.94328601
63MAP3K110.92627374
64MAPKAPK30.90922696
65RAF10.89825701
66DAPK10.89021251
67MTOR0.87287269
68PLK30.87014296
69ICK0.86179717
70CDK20.85062012
71ATM0.81967866
72TAOK20.80906252
73CCNB10.80743908
74RPS6KA40.78548173
75PIM20.76210084
76TRIB30.71467227
77FGFR40.71072887
78ARAF0.70460203
79AKT20.68108148
80GRK60.66870837
81BRAF0.66842835
82PRKCI0.66586496
83AKT30.65205079
84ERBB40.63790937
85CSNK2A20.63322617
86MAP3K30.63146722
87MET0.62925328
88DAPK30.60259588
89EIF2AK20.60206887
90IRAK40.58983551
91BRSK10.58045681
92PAK10.56638958
93BMX0.55000800
94ILK0.54570994
95JAK30.54008294
96CDK10.53908464
97TGFBR10.53892014
98SIK30.53801867
99CSNK2A10.53687007
100ZAP700.51731601
101STK30.50837930
102BLK0.49704182
103LMTK20.49255563
104BTK0.49120869
105CDK60.49025782
106TESK10.48393059
107RPS6KA50.48075632
108KDR0.47517307
109CDK90.47069494
110CLK10.42619652
111MAP2K60.42498062
112IKBKB0.41879779
113MELK0.40998700
114STK240.40299837
115MAPK110.40022825
116PDK30.39979653
117PDK40.39979653
118CSNK1E0.38275501
119CHUK0.38147442
120ABL20.37937121
121RPS6KC10.37906528
122RPS6KL10.37906528
123ERN10.37853519
124LATS20.36826605
125OBSCN0.35874395
126MST40.34976835
127RPS6KA60.32793778
128TXK0.32446502
129LRRK20.32307825
130IRAK20.31392135
131RPS6KA10.29758636
132MAPKAPK20.29098997
133MAPK140.28262774
134CSNK1G30.28115354
135AKT10.27852815

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.35618342
2Mismatch repair_Homo sapiens_hsa034303.78110575
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.57175056
4One carbon pool by folate_Homo sapiens_hsa006703.43226761
5Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.80383275
6Ribosome_Homo sapiens_hsa030102.76322348
7RNA transport_Homo sapiens_hsa030132.74974546
8Spliceosome_Homo sapiens_hsa030402.72397602
9Homologous recombination_Homo sapiens_hsa034402.70997985
10RNA polymerase_Homo sapiens_hsa030202.70614100
11Base excision repair_Homo sapiens_hsa034102.64431233
12Fanconi anemia pathway_Homo sapiens_hsa034602.31070276
13Nucleotide excision repair_Homo sapiens_hsa034202.24321931
14Pyrimidine metabolism_Homo sapiens_hsa002402.18985290
15Cell cycle_Homo sapiens_hsa041102.04716729
16Proteasome_Homo sapiens_hsa030502.03731206
172-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.70692570
18Non-homologous end-joining_Homo sapiens_hsa034501.60076085
19RNA degradation_Homo sapiens_hsa030181.51887909
20Cyanoamino acid metabolism_Homo sapiens_hsa004601.51087396
21mRNA surveillance pathway_Homo sapiens_hsa030151.49266874
22Biosynthesis of amino acids_Homo sapiens_hsa012301.48271631
23Systemic lupus erythematosus_Homo sapiens_hsa053221.40567952
24p53 signaling pathway_Homo sapiens_hsa041151.36461847
25Selenocompound metabolism_Homo sapiens_hsa004501.29479855
26Basal transcription factors_Homo sapiens_hsa030221.28801334
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.27603932
28Carbon metabolism_Homo sapiens_hsa012001.22839851
29Sulfur relay system_Homo sapiens_hsa041221.22429540
30Pentose phosphate pathway_Homo sapiens_hsa000301.19393232
31Drug metabolism - other enzymes_Homo sapiens_hsa009831.17210308
32Alcoholism_Homo sapiens_hsa050341.15616925
33Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.14661001
34Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.12644765
35N-Glycan biosynthesis_Homo sapiens_hsa005101.08755919
36Vitamin B6 metabolism_Homo sapiens_hsa007501.07534553
37Purine metabolism_Homo sapiens_hsa002301.07407304
38Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.04494477
39Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.03998604
40Lysine degradation_Homo sapiens_hsa003101.02572716
41Fatty acid elongation_Homo sapiens_hsa000621.01034924
42Other glycan degradation_Homo sapiens_hsa005110.98539033
43Folate biosynthesis_Homo sapiens_hsa007900.98365871
44Epstein-Barr virus infection_Homo sapiens_hsa051690.98055947
45Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.96981806
46Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.96182585
47Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.95884700
48Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.91815069
49Fructose and mannose metabolism_Homo sapiens_hsa000510.90052008
50Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.88690539
51Herpes simplex infection_Homo sapiens_hsa051680.88045795
52Viral carcinogenesis_Homo sapiens_hsa052030.86640995
53Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.75621254
54Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.74497317
55Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.73993574
56Glutathione metabolism_Homo sapiens_hsa004800.70617686
57Sulfur metabolism_Homo sapiens_hsa009200.70252487
58Galactose metabolism_Homo sapiens_hsa000520.66934307
59Primary immunodeficiency_Homo sapiens_hsa053400.65050091
60Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.63702923
61Antigen processing and presentation_Homo sapiens_hsa046120.63526513
62Arginine and proline metabolism_Homo sapiens_hsa003300.63048591
63NF-kappa B signaling pathway_Homo sapiens_hsa040640.62505321
64Steroid biosynthesis_Homo sapiens_hsa001000.62503490
65HTLV-I infection_Homo sapiens_hsa051660.61803484
66Chronic myeloid leukemia_Homo sapiens_hsa052200.61493816
67Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.58561372
68Transcriptional misregulation in cancer_Homo sapiens_hsa052020.53028148
69beta-Alanine metabolism_Homo sapiens_hsa004100.52260588
70Notch signaling pathway_Homo sapiens_hsa043300.51179205
71Fatty acid degradation_Homo sapiens_hsa000710.49877212
72Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.49694763
73Fatty acid metabolism_Homo sapiens_hsa012120.46873545
74Pyruvate metabolism_Homo sapiens_hsa006200.46666511
75Small cell lung cancer_Homo sapiens_hsa052220.46500478
76Oocyte meiosis_Homo sapiens_hsa041140.44656241
77Acute myeloid leukemia_Homo sapiens_hsa052210.44390271
78Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.43560625
79Apoptosis_Homo sapiens_hsa042100.42797562
80Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.42241455
81Phenylalanine metabolism_Homo sapiens_hsa003600.41143209
82MicroRNAs in cancer_Homo sapiens_hsa052060.41110429
83Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.38610011
84Measles_Homo sapiens_hsa051620.37991149
85Non-small cell lung cancer_Homo sapiens_hsa052230.37193166
86Legionellosis_Homo sapiens_hsa051340.36495874
87Metabolic pathways_Homo sapiens_hsa011000.36424776
88Huntingtons disease_Homo sapiens_hsa050160.36120642
89Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.35950907
90Central carbon metabolism in cancer_Homo sapiens_hsa052300.35371465
91Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.35250323
92Oxidative phosphorylation_Homo sapiens_hsa001900.35171651
93Hepatitis B_Homo sapiens_hsa051610.33443482
94Thyroid cancer_Homo sapiens_hsa052160.32127323
95Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.31825110
96Vibrio cholerae infection_Homo sapiens_hsa051100.31522828
97Pancreatic cancer_Homo sapiens_hsa052120.31307832
98Vitamin digestion and absorption_Homo sapiens_hsa049770.30031582
99HIF-1 signaling pathway_Homo sapiens_hsa040660.29799768
100Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.28936910
101Basal cell carcinoma_Homo sapiens_hsa052170.28831240
102Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.28292692
103Tryptophan metabolism_Homo sapiens_hsa003800.27914936
104Viral myocarditis_Homo sapiens_hsa054160.26198859
105Intestinal immune network for IgA production_Homo sapiens_hsa046720.25939575
106Fat digestion and absorption_Homo sapiens_hsa049750.25479645
107Pentose and glucuronate interconversions_Homo sapiens_hsa000400.24392447
108Propanoate metabolism_Homo sapiens_hsa006400.24359367
109Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.22949911
110Bladder cancer_Homo sapiens_hsa052190.21078963
111Shigellosis_Homo sapiens_hsa051310.20747591
112Fatty acid biosynthesis_Homo sapiens_hsa000610.20586218
113Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.19516331
114Insulin signaling pathway_Homo sapiens_hsa049100.19358607
115RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.19130506
116Hematopoietic cell lineage_Homo sapiens_hsa046400.18680996
117Tyrosine metabolism_Homo sapiens_hsa003500.18018368
118Starch and sucrose metabolism_Homo sapiens_hsa005000.17894279
119Colorectal cancer_Homo sapiens_hsa052100.17808443
120Influenza A_Homo sapiens_hsa051640.17656852
121Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.15757281
122Arginine biosynthesis_Homo sapiens_hsa002200.15340761
123Parkinsons disease_Homo sapiens_hsa050120.14325401

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