TCAIM

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)6.30214188
2L-phenylalanine catabolic process (GO:0006559)6.30214188
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)5.93703150
4L-phenylalanine metabolic process (GO:0006558)5.93703150
5aromatic amino acid family catabolic process (GO:0009074)5.45850901
6glyoxylate metabolic process (GO:0046487)5.11095083
7lysine metabolic process (GO:0006553)5.05882148
8lysine catabolic process (GO:0006554)5.05882148
9cellular ketone body metabolic process (GO:0046950)4.86265604
10fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.79741364
11kynurenine metabolic process (GO:0070189)4.78378706
12bile acid biosynthetic process (GO:0006699)4.78023530
13tryptophan catabolic process (GO:0006569)4.77725539
14indole-containing compound catabolic process (GO:0042436)4.77725539
15indolalkylamine catabolic process (GO:0046218)4.77725539
16aspartate family amino acid catabolic process (GO:0009068)4.75637136
17cysteine metabolic process (GO:0006534)4.63812410
18tryptophan metabolic process (GO:0006568)4.53956500
19L-methionine salvage (GO:0071267)4.49968162
20L-methionine biosynthetic process (GO:0071265)4.49968162
21amino acid salvage (GO:0043102)4.49968162
22alpha-linolenic acid metabolic process (GO:0036109)4.49013150
23amino-acid betaine metabolic process (GO:0006577)4.38488534
24triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.31035238
25coenzyme catabolic process (GO:0009109)4.28559510
26short-chain fatty acid metabolic process (GO:0046459)4.28442841
27fatty acid beta-oxidation (GO:0006635)4.24183909
28L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.21977524
29ketone body metabolic process (GO:1902224)4.18427269
302-oxoglutarate metabolic process (GO:0006103)4.16221621
31dicarboxylic acid biosynthetic process (GO:0043650)4.10309810
32homocysteine metabolic process (GO:0050667)4.08934890
33alpha-amino acid catabolic process (GO:1901606)4.08744202
34acetyl-CoA metabolic process (GO:0006084)4.06489248
35ethanol oxidation (GO:0006069)4.05814130
36sulfur amino acid catabolic process (GO:0000098)4.04706720
37glutamate metabolic process (GO:0006536)4.02691608
38serine family amino acid catabolic process (GO:0009071)4.01705187
39fatty acid oxidation (GO:0019395)3.98743697
40fatty acid catabolic process (GO:0009062)3.96503596
41aromatic amino acid family metabolic process (GO:0009072)3.94804424
42lipid oxidation (GO:0034440)3.94223795
43drug transmembrane transport (GO:0006855)3.93412214
44bile acid metabolic process (GO:0008206)3.91871616
45valine metabolic process (GO:0006573)3.91053915
46cellular amino acid catabolic process (GO:0009063)3.88132718
47monocarboxylic acid catabolic process (GO:0072329)3.85970147
48branched-chain amino acid catabolic process (GO:0009083)3.84789929
49regulation of triglyceride catabolic process (GO:0010896)3.81198424
50positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.80040786
51fatty acid transmembrane transport (GO:1902001)3.79950887
52urea metabolic process (GO:0019627)3.78007638
53urea cycle (GO:0000050)3.78007638
54tyrosine metabolic process (GO:0006570)3.77410854
55carnitine metabolic process (GO:0009437)3.77101602
56regulation of skeletal muscle contraction (GO:0014819)3.74869349
57carnitine shuttle (GO:0006853)3.73390274
58complement activation, alternative pathway (GO:0006957)3.73080829
59branched-chain amino acid metabolic process (GO:0009081)3.71589071
60regulation of protein activation cascade (GO:2000257)3.65084188
61carboxylic acid catabolic process (GO:0046395)3.64547610
62organic acid catabolic process (GO:0016054)3.64547610
63cellular modified amino acid catabolic process (GO:0042219)3.63157546
64drug catabolic process (GO:0042737)3.61662927
65S-adenosylmethionine metabolic process (GO:0046500)3.61006203
66methionine biosynthetic process (GO:0009086)3.60118370
67heme transport (GO:0015886)3.59067987
68urate metabolic process (GO:0046415)3.58338782
69high-density lipoprotein particle remodeling (GO:0034375)3.50228486
70nitrogen cycle metabolic process (GO:0071941)3.47063743
71indolalkylamine metabolic process (GO:0006586)3.46118130
72triglyceride homeostasis (GO:0070328)3.45941456
73acylglycerol homeostasis (GO:0055090)3.45941456
74muscle filament sliding (GO:0030049)3.45891554
75actin-myosin filament sliding (GO:0033275)3.45891554
76negative regulation of fibrinolysis (GO:0051918)3.45202893
77regulation of fibrinolysis (GO:0051917)3.44624481
78succinate metabolic process (GO:0006105)3.44378838
79peptidyl-glutamic acid carboxylation (GO:0017187)3.43880095
80protein carboxylation (GO:0018214)3.43880095
81regulation of complement activation (GO:0030449)3.43219712
82amine catabolic process (GO:0009310)3.40570420
83cellular biogenic amine catabolic process (GO:0042402)3.40570420
84response to nitrosative stress (GO:0051409)3.38546150
85dicarboxylic acid catabolic process (GO:0043649)3.37509492
86tricarboxylic acid cycle (GO:0006099)3.35712570
87amino-acid betaine transport (GO:0015838)3.31188122
88carnitine transport (GO:0015879)3.31188122
89pyrimidine nucleobase catabolic process (GO:0006208)3.29521295
90regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.28609816
91methionine metabolic process (GO:0006555)3.27927978
92exogenous drug catabolic process (GO:0042738)3.25450559
93serine family amino acid metabolic process (GO:0009069)3.23382433
94xenobiotic catabolic process (GO:0042178)3.23351406
95regulation of bile acid biosynthetic process (GO:0070857)3.20000695
96regulation of acyl-CoA biosynthetic process (GO:0050812)3.19827915
97aspartate family amino acid biosynthetic process (GO:0009067)3.19423318
98regulation of glucokinase activity (GO:0033131)3.13931658
99regulation of hexokinase activity (GO:1903299)3.13931658
100quaternary ammonium group transport (GO:0015697)3.13717461
101carnitine transmembrane transport (GO:1902603)3.13570481
102small molecule catabolic process (GO:0044282)3.13080180
103biotin metabolic process (GO:0006768)3.12217000
104protein-lipid complex remodeling (GO:0034368)3.11350989
105macromolecular complex remodeling (GO:0034367)3.11350989
106plasma lipoprotein particle remodeling (GO:0034369)3.11350989
107thioester metabolic process (GO:0035383)3.11089594
108acyl-CoA metabolic process (GO:0006637)3.11089594
109cofactor catabolic process (GO:0051187)3.10937163
110bile acid and bile salt transport (GO:0015721)3.10837246
111reverse cholesterol transport (GO:0043691)3.10271842
112cellular glucuronidation (GO:0052695)3.09216351
113benzene-containing compound metabolic process (GO:0042537)3.08373126
114arginine metabolic process (GO:0006525)3.08187027
115regulation of cholesterol metabolic process (GO:0090181)3.05963279
116phospholipid homeostasis (GO:0055091)3.04867564
117response to mercury ion (GO:0046689)3.04045739
118very long-chain fatty acid metabolic process (GO:0000038)3.02811339
119seminiferous tubule development (GO:0072520)3.00933821
120actin-mediated cell contraction (GO:0070252)3.00587309
121regulation of cholesterol esterification (GO:0010872)3.00029966
122drug transport (GO:0015893)2.97660068
123protein prenylation (GO:0018342)2.97434533
124prenylation (GO:0097354)2.97434533
125regulation of relaxation of muscle (GO:1901077)2.97027497
126magnesium ion transport (GO:0015693)2.95202387
127regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.91336389
128response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.89975195
129nitric oxide mediated signal transduction (GO:0007263)2.87994943
130arginine catabolic process (GO:0006527)2.87107721
131cholesterol biosynthetic process (GO:0006695)2.87076751
132regulation of sulfur metabolic process (GO:0042762)2.86112602
133peroxisome fission (GO:0016559)2.85965737
134heparin biosynthetic process (GO:0030210)2.85869255
135heparin metabolic process (GO:0030202)2.85869255
136nucleobase catabolic process (GO:0046113)2.85614552
137regulation of cofactor metabolic process (GO:0051193)2.83612099
138regulation of coenzyme metabolic process (GO:0051196)2.83612099
139sterol biosynthetic process (GO:0016126)2.80161696
140peptidyl-histidine modification (GO:0018202)2.79660830
141lipid particle organization (GO:0034389)2.78023774
142quinone metabolic process (GO:1901661)2.77050757
143sulfur amino acid biosynthetic process (GO:0000097)2.76720255
144negative regulation of protein activation cascade (GO:2000258)2.76712851
145water-soluble vitamin biosynthetic process (GO:0042364)2.75960480
146polyketide metabolic process (GO:0030638)2.75449538
147doxorubicin metabolic process (GO:0044598)2.75449538
148daunorubicin metabolic process (GO:0044597)2.75449538
149inositol phosphate catabolic process (GO:0071545)2.71162513
150ubiquinone metabolic process (GO:0006743)2.70114714
151inositol phosphate dephosphorylation (GO:0046855)2.66014658
152phosphorylated carbohydrate dephosphorylation (GO:0046838)2.66014658
153macroautophagy (GO:0016236)2.63718885
154isoprenoid biosynthetic process (GO:0008299)2.63367430
155signal peptide processing (GO:0006465)2.63132374
156nucleotide transmembrane transport (GO:1901679)2.61869663
157adenosine metabolic process (GO:0046085)2.59217224

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse6.99011190
2RXR_22158963_ChIP-Seq_LIVER_Mouse5.06761413
3EGR1_23403033_ChIP-Seq_LIVER_Mouse4.26621717
4LXR_22158963_ChIP-Seq_LIVER_Mouse4.12442457
5PPARA_22158963_ChIP-Seq_LIVER_Mouse4.12389529
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.49966145
7FOXO1_23066095_ChIP-Seq_LIVER_Mouse3.20092787
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.70563815
9ZNF274_21170338_ChIP-Seq_K562_Hela2.53736075
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.36574247
11PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.36187937
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.31468933
13CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.17661344
14GBX2_23144817_ChIP-Seq_PC3_Human2.16372110
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.14633669
16FUS_26573619_Chip-Seq_HEK293_Human2.11895755
17ELK1_19687146_ChIP-ChIP_HELA_Human2.05554796
18TAF15_26573619_Chip-Seq_HEK293_Human1.96765041
19CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.96394753
20BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.93874040
21SALL1_21062744_ChIP-ChIP_HESCs_Human1.93177468
22CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.92155732
23TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.84649146
24GABP_17652178_ChIP-ChIP_JURKAT_Human1.79731971
25ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.79389544
26EWS_26573619_Chip-Seq_HEK293_Human1.71143520
27HTT_18923047_ChIP-ChIP_STHdh_Human1.63362628
28HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.58796190
29GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52394595
30ELF1_17652178_ChIP-ChIP_JURKAT_Human1.46603753
31EST1_17652178_ChIP-ChIP_JURKAT_Human1.45434243
32ZFP57_27257070_Chip-Seq_ESCs_Mouse1.38040144
33FOXA2_19822575_ChIP-Seq_HepG2_Human1.36539973
34TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.35351484
35CDX2_19796622_ChIP-Seq_MESCs_Mouse1.33688906
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32085824
37EP300_21415370_ChIP-Seq_HL-1_Mouse1.31783229
38VDR_22108803_ChIP-Seq_LS180_Human1.30425719
39SRF_21415370_ChIP-Seq_HL-1_Mouse1.30253191
40NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.28627187
41AR_21572438_ChIP-Seq_LNCaP_Human1.28433345
42GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.28051995
43MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.28028520
44AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.26550057
45ESR1_20079471_ChIP-ChIP_T-47D_Human1.26296131
46KLF5_20875108_ChIP-Seq_MESCs_Mouse1.25190685
47BCAT_22108803_ChIP-Seq_LS180_Human1.25115905
48POU3F2_20337985_ChIP-ChIP_501MEL_Human1.24742072
49PADI4_21655091_ChIP-ChIP_MCF-7_Human1.24132979
50* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.23926844
51TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.22720595
52FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.21357493
53SMAD4_21799915_ChIP-Seq_A2780_Human1.19900043
54AUTS2_25519132_ChIP-Seq_293T-REX_Human1.19578782
55EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.18258810
56SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.16848301
57P53_22387025_ChIP-Seq_ESCs_Mouse1.16313912
58TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.16205065
59NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.15447197
60NRF2_20460467_ChIP-Seq_MEFs_Mouse1.15447197
61E2F1_18555785_Chip-Seq_ESCs_Mouse1.13810479
62FOXA1_21572438_ChIP-Seq_LNCaP_Human1.12939370
63EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12278803
64PIAS1_25552417_ChIP-Seq_VCAP_Human1.12058627
65VDR_23849224_ChIP-Seq_CD4+_Human1.11541448
66PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.10992213
67GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.10208260
68FOXM1_26456572_ChIP-Seq_MCF-7_Human1.10189581
69SMAD3_21741376_ChIP-Seq_EPCs_Human1.10154371
70TCF4_22108803_ChIP-Seq_LS180_Human1.10146745
71CTBP1_25329375_ChIP-Seq_LNCAP_Human1.07921016
72MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06942956
73SUZ12_27294783_Chip-Seq_NPCs_Mouse1.06514256
74STAT3_18555785_Chip-Seq_ESCs_Mouse1.05310145
75SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04875224
76UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.04562287
77KAP1_22055183_ChIP-Seq_ESCs_Mouse1.03671321
78EZH2_27294783_Chip-Seq_NPCs_Mouse1.03198924
79FLI1_27457419_Chip-Seq_LIVER_Mouse1.03084002
80JUN_21703547_ChIP-Seq_K562_Human1.03081959
81PCGF2_27294783_Chip-Seq_NPCs_Mouse1.02711059
82CMYC_18555785_Chip-Seq_ESCs_Mouse1.02159519
83OCT4_18555785_Chip-Seq_ESCs_Mouse1.02062120
84STAT3_23295773_ChIP-Seq_U87_Human1.02027151
85CREB1_15753290_ChIP-ChIP_HEK293T_Human1.01693354
86AR_20517297_ChIP-Seq_VCAP_Human1.01676837
87P300_19829295_ChIP-Seq_ESCs_Human1.00658591
88SUZ12_18555785_Chip-Seq_ESCs_Mouse0.99998624
89BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.98743273
90CTCF_18555785_Chip-Seq_ESCs_Mouse0.97784855
91HNF4A_19822575_ChIP-Seq_HepG2_Human0.97769197
92CTBP2_25329375_ChIP-Seq_LNCAP_Human0.96421546
93GATA1_22025678_ChIP-Seq_K562_Human0.96390044
94PCGF2_27294783_Chip-Seq_ESCs_Mouse0.95533716
95CBP_21632823_ChIP-Seq_H3396_Human0.95374162
96MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.95009102
97CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.93629375
98KDM2B_26808549_Chip-Seq_REH_Human0.92692336
99CRX_20693478_ChIP-Seq_RETINA_Mouse0.92531580
100NFE2_27457419_Chip-Seq_LIVER_Mouse0.90852725
101SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.90178775
102SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.88570226
103AR_25329375_ChIP-Seq_VCAP_Human0.87914882
104MTF2_20144788_ChIP-Seq_MESCs_Mouse0.87362933
105PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.86740029
106SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.86014916
107ER_23166858_ChIP-Seq_MCF-7_Human0.85985586
108SMAD4_21741376_ChIP-Seq_EPCs_Human0.85859364
109TBL1_22424771_ChIP-Seq_293T_Human0.85846604
110TBX20_22080862_ChIP-Seq_HEART_Mouse0.85647672
111TBX20_22328084_ChIP-Seq_HEART_Mouse0.85647672
112CBP_20019798_ChIP-Seq_JUKART_Human0.85407165
113IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.85407165
114SOX2_21211035_ChIP-Seq_LN229_Gbm0.84902075
115TCF4_23295773_ChIP-Seq_U87_Human0.84543574
116STAT1_17558387_ChIP-Seq_HELA_Human0.84202894
117IGF1R_20145208_ChIP-Seq_DFB_Human0.83805479
118RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.81694380
119TOP2B_26459242_ChIP-Seq_MCF-7_Human0.81165277
120HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.80981976
121EZH2_22144423_ChIP-Seq_EOC_Human0.80786113
122TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.80574614
123ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.80264003
124NR3C1_21868756_ChIP-Seq_MCF10A_Human0.80197774
125NANOG_18555785_Chip-Seq_ESCs_Mouse0.80045524
126AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.79874519
127NR3C1_23031785_ChIP-Seq_PC12_Mouse0.79799034
128OCT4_21477851_ChIP-Seq_ESCs_Mouse0.79743904
129PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.79500592
130SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.79035781
131EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.78733216
132ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.78476672
133RUNX1_27457419_Chip-Seq_LIVER_Mouse0.78264306
134MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.78111121
135ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.77641811
136SOX2_19829295_ChIP-Seq_ESCs_Human0.77298945
137NANOG_19829295_ChIP-Seq_ESCs_Human0.77298945
138EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.76689074
139SOX2_18555785_Chip-Seq_ESCs_Mouse0.76287152
140TAL1_26923725_Chip-Seq_HPCs_Mouse0.75758169
141OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.75550237
142FLI1_21867929_ChIP-Seq_TH2_Mouse0.75261375
143CDX2_22108803_ChIP-Seq_LS180_Human0.75123083

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system6.29942134
2MP0005360_urolithiasis6.00791580
3MP0005085_abnormal_gallbladder_physiolo4.94635541
4MP0005365_abnormal_bile_salt4.75414678
5MP0008875_abnormal_xenobiotic_pharmacok4.07117764
6MP0000569_abnormal_digit_pigmentation3.91488119
7MP0003806_abnormal_nucleotide_metabolis3.54962050
8MP0002837_dystrophic_cardiac_calcinosis3.31285192
9MP0003646_muscle_fatigue3.14483249
10MP0003252_abnormal_bile_duct2.83899385
11MP0005332_abnormal_amino_acid2.80629150
12MP0003195_calcinosis2.71720508
13MP0005084_abnormal_gallbladder_morpholo2.71438904
14MP0010329_abnormal_lipoprotein_level2.63952005
15MP0009840_abnormal_foam_cell2.07654699
16MP0005451_abnormal_body_composition2.02964969
17MP0005645_abnormal_hypothalamus_physiol2.01699163
18MP0004130_abnormal_muscle_cell1.97749564
19MP0002118_abnormal_lipid_homeostasis1.93036041
20MP0005670_abnormal_white_adipose1.91498280
21MP0004036_abnormal_muscle_relaxation1.88986168
22MP0006036_abnormal_mitochondrial_physio1.87636510
23MP0001666_abnormal_nutrient_absorption1.84421784
24MP0004043_abnormal_pH_regulation1.81944669
25MP0003950_abnormal_plasma_membrane1.81325159
26MP0004215_abnormal_myocardial_fiber1.70748447
27MP0005083_abnormal_biliary_tract1.68414176
28MP0000751_myopathy1.67859955
29MP0004019_abnormal_vitamin_homeostasis1.64729838
30MP0000372_irregular_coat_pigmentation1.62772316
31MP0000013_abnormal_adipose_tissue1.62039296
32MP0005584_abnormal_enzyme/coenzyme_acti1.59909954
33MP0005319_abnormal_enzyme/_coenzyme1.54079489
34MP0003868_abnormal_feces_composition1.53564972
35MP0000749_muscle_degeneration1.49157020
36MP0000609_abnormal_liver_physiology1.48824946
37MP0002138_abnormal_hepatobiliary_system1.46573464
38MP0009780_abnormal_chondrocyte_physiolo1.39413695
39MP0006054_spinal_hemorrhage1.38628150
40MP0004084_abnormal_cardiac_muscle1.37350018
41MP0005330_cardiomyopathy1.37017992
42MP0005535_abnormal_body_temperature1.36612822
43MP0002102_abnormal_ear_morphology1.31797351
44MP0002638_abnormal_pupillary_reflex1.31089781
45MP0009643_abnormal_urine_homeostasis1.30149093
46MP0003329_amyloid_beta_deposits1.27768557
47MP0009697_abnormal_copulation1.25667062
48MP0002090_abnormal_vision1.24484037
49MP0002269_muscular_atrophy1.24248571
50MP0005620_abnormal_muscle_contractility1.23555297
51MP0005666_abnormal_adipose_tissue1.22497591
52MP0000747_muscle_weakness1.22305470
53MP0005174_abnormal_tail_pigmentation1.21374494
54MP0004147_increased_porphyrin_level1.20800828
55MP0003191_abnormal_cellular_cholesterol1.18301572
56MP0005408_hypopigmentation1.17749575
57MP0006035_abnormal_mitochondrial_morpho1.16028040
58MP0001764_abnormal_homeostasis1.14255935
59MP0006276_abnormal_autonomic_nervous1.13933990
60MP0003690_abnormal_glial_cell1.12217452
61MP0005253_abnormal_eye_physiology1.11522262
62MP0006072_abnormal_retinal_apoptosis1.11111373
63MP0004145_abnormal_muscle_electrophysio1.09832609
64MP0008058_abnormal_DNA_repair1.07831908
65MP0005187_abnormal_penis_morphology1.06571076
66MP0002972_abnormal_cardiac_muscle1.06509499
67MP0003186_abnormal_redox_activity1.05903401
68MP0002078_abnormal_glucose_homeostasis1.04444577
69MP0004087_abnormal_muscle_fiber1.03984029
70MP0002971_abnormal_brown_adipose1.02678815
71MP0004484_altered_response_of1.00429545
72MP0000230_abnormal_systemic_arterial1.00149341
73MP0003656_abnormal_erythrocyte_physiolo0.98997283
74MP0003221_abnormal_cardiomyocyte_apopto0.97908563
75MP0005636_abnormal_mineral_homeostasis0.97634067
76MP0001986_abnormal_taste_sensitivity0.95736968
77MP0005220_abnormal_exocrine_pancreas0.95143020
78MP0003137_abnormal_impulse_conducting0.94031748
79MP0003011_delayed_dark_adaptation0.93902847
80MP0005167_abnormal_blood-brain_barrier0.92729401
81MP0002909_abnormal_adrenal_gland0.91032718
82MP0005647_abnormal_sex_gland0.90691454
83MP0008775_abnormal_heart_ventricle0.90463326
84MP0005266_abnormal_metabolism0.90145724
85MP0002234_abnormal_pharynx_morphology0.89636064
86MP0010234_abnormal_vibrissa_follicle0.89322200
87MP0000604_amyloidosis0.88211981
88MP0004233_abnormal_muscle_weight0.87357370
89MP0004085_abnormal_heartbeat0.85933466
90MP0004270_analgesia0.85840080
91MP0002876_abnormal_thyroid_physiology0.85706032
92MP0002332_abnormal_exercise_endurance0.82931225
93MP0005410_abnormal_fertilization0.82842560
94MP0005334_abnormal_fat_pad0.81588836
95MP0005551_abnormal_eye_electrophysiolog0.81298799
96MP0002928_abnormal_bile_duct0.80951094
97MP0001765_abnormal_ion_homeostasis0.80797081
98MP0001661_extended_life_span0.79977745
99MP0001756_abnormal_urination0.79692750
100MP0002106_abnormal_muscle_physiology0.79345306
101MP0002822_catalepsy0.76009913
102MP0006138_congestive_heart_failure0.75907376
103MP0005385_cardiovascular_system_phenoty0.75795934
104MP0001544_abnormal_cardiovascular_syste0.75795934
105MP0002272_abnormal_nervous_system0.72341314
106MP0003631_nervous_system_phenotype0.70966758
107MP0009046_muscle_twitch0.70317855
108MP0009642_abnormal_blood_homeostasis0.69839550
109MP0005646_abnormal_pituitary_gland0.69350122
110MP0000759_abnormal_skeletal_muscle0.66021974
111MP0003633_abnormal_nervous_system0.65062310
112MP0005369_muscle_phenotype0.64888926
113MP0005376_homeostasis/metabolism_phenot0.64705889
114MP0010368_abnormal_lymphatic_system0.64653559
115MP0002229_neurodegeneration0.63633120
116MP0002064_seizures0.60157847
117MP0008874_decreased_physiological_sensi0.60048822
118MP0009745_abnormal_behavioral_response0.59308318
119MP0004924_abnormal_behavior0.59052838
120MP0005386_behavior/neurological_phenoty0.59052838
121MP0000598_abnormal_liver_morphology0.59007719
122MP0001529_abnormal_vocalization0.58776604
123MP0003718_maternal_effect0.58738732
124MP0009384_cardiac_valve_regurgitation0.58426143
125MP0009764_decreased_sensitivity_to0.58106577
126MP0004142_abnormal_muscle_tone0.57187114
127MP0010630_abnormal_cardiac_muscle0.56919347
128MP0000920_abnormal_myelination0.56614317
129MP0001440_abnormal_grooming_behavior0.56219108

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)5.35745075
2Intrahepatic cholestasis (HP:0001406)5.10792874
3Deep venous thrombosis (HP:0002625)4.75399832
4Hyperlipoproteinemia (HP:0010980)4.66318423
5Ketosis (HP:0001946)4.61539962
6Xanthomatosis (HP:0000991)4.45408631
7Ketoacidosis (HP:0001993)4.40880413
8Nemaline bodies (HP:0003798)4.39915292
9Muscle fiber inclusion bodies (HP:0100299)4.32338301
10Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)4.18088464
11Prolonged partial thromboplastin time (HP:0003645)4.11270542
12Hyperammonemia (HP:0001987)4.07397192
13Hyperglycinuria (HP:0003108)4.02955201
14Abnormality of serine family amino acid metabolism (HP:0010894)3.93261621
15Abnormality of glycine metabolism (HP:0010895)3.93261621
16Abnormality of monocarboxylic acid metabolism (HP:0010996)3.82962031
17Hypoglycemic coma (HP:0001325)3.80000157
18Hyperglycinemia (HP:0002154)3.74376971
19Hypobetalipoproteinemia (HP:0003563)3.63451983
20Abnormality of fatty-acid metabolism (HP:0004359)3.59397232
21Gout (HP:0001997)3.49223129
22Complement deficiency (HP:0004431)3.43909301
23Abnormality of aspartate family amino acid metabolism (HP:0010899)3.42799972
24Exercise-induced myalgia (HP:0003738)3.34992755
25Cerebral edema (HP:0002181)3.29135843
26Dicarboxylic aciduria (HP:0003215)3.28174642
27Abnormality of dicarboxylic acid metabolism (HP:0010995)3.28174642
28Myoglobinuria (HP:0002913)3.27517106
29Epidermoid cyst (HP:0200040)3.22957756
30Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.22724546
31Hypoalphalipoproteinemia (HP:0003233)3.15715230
32Hypolipoproteinemia (HP:0010981)3.15293863
33Abnormality of glutamine family amino acid metabolism (HP:0010902)3.11855378
34Abnormality of methionine metabolism (HP:0010901)3.11040838
35Abnormality of alanine metabolism (HP:0010916)3.08085384
36Hyperalaninemia (HP:0003348)3.08085384
37Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.08085384
38Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.04301381
39Abnormality of sulfur amino acid metabolism (HP:0004339)3.04284697
40Metabolic acidosis (HP:0001942)2.99045999
41Abnormality of purine metabolism (HP:0004352)2.97787025
42Generalized aminoaciduria (HP:0002909)2.89032183
43Abnormality of serum amino acid levels (HP:0003112)2.88036191
44Fat malabsorption (HP:0002630)2.83366404
45Proximal tubulopathy (HP:0000114)2.82272551
46Lethargy (HP:0001254)2.81386595
47Conjugated hyperbilirubinemia (HP:0002908)2.81300909
48Exercise-induced muscle cramps (HP:0003710)2.76007703
49Joint hemorrhage (HP:0005261)2.74004410
50Calf muscle hypertrophy (HP:0008981)2.70629663
51Delayed CNS myelination (HP:0002188)2.67608675
52Rimmed vacuoles (HP:0003805)2.66907366
53Acute encephalopathy (HP:0006846)2.66736502
54Hyperuricemia (HP:0002149)2.64088306
55Increased purine levels (HP:0004368)2.64088306
56Muscle hypertrophy of the lower extremities (HP:0008968)2.62193461
57Hypothermia (HP:0002045)2.61060735
58Hyperinsulinemic hypoglycemia (HP:0000825)2.59724432
59Fetal akinesia sequence (HP:0001989)2.52424301
60Abnormality of nucleobase metabolism (HP:0010932)2.51153217
61Cardiovascular calcification (HP:0011915)2.48270904
62Abnormality of the common coagulation pathway (HP:0010990)2.47111577
63Palpitations (HP:0001962)2.47043444
64Sensorimotor neuropathy (HP:0007141)2.46887534
65Sudden death (HP:0001699)2.46034078
66Fair hair (HP:0002286)2.45323712
67Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.43526762
68Degeneration of the lateral corticospinal tracts (HP:0002314)2.43526762
69Hepatocellular necrosis (HP:0001404)2.42025019
70Abnormality of the intrinsic pathway (HP:0010989)2.41318274
71Hepatic necrosis (HP:0002605)2.39202509
72CNS demyelination (HP:0007305)2.38293136
73Mitochondrial inheritance (HP:0001427)2.37942141
74Vomiting (HP:0002013)2.35517952
75Cholecystitis (HP:0001082)2.31978984
76Abnormal gallbladder physiology (HP:0012438)2.31978984
77Increased serum pyruvate (HP:0003542)2.31241286
78Cholelithiasis (HP:0001081)2.30427078
79Increased CSF lactate (HP:0002490)2.28937575
80Abnormality of the renal cortex (HP:0011035)2.27823061
81Hyperbilirubinemia (HP:0002904)2.27129477
82Skin nodule (HP:0200036)2.25926148
83Abnormal gallbladder morphology (HP:0012437)2.24034941
84Abnormal mitochondria in muscle tissue (HP:0008316)2.21120468
85Rhabdomyolysis (HP:0003201)2.19638460
86Heart block (HP:0012722)2.17236591
87Increased muscle lipid content (HP:0009058)2.15156348
88Atrioventricular block (HP:0001678)2.14405300
89Lipid accumulation in hepatocytes (HP:0006561)2.13475196
90Steatorrhea (HP:0002570)2.12896094
91Spontaneous abortion (HP:0005268)2.12636943
92Neuroendocrine neoplasm (HP:0100634)2.12476708
93Hyperglycemia (HP:0003074)2.12346008
94Glycosuria (HP:0003076)2.12281521
95Abnormality of urine glucose concentration (HP:0011016)2.12281521
96Hypercholesterolemia (HP:0003124)2.11856917
97Hyporeflexia of lower limbs (HP:0002600)2.11312683
98Hypoglycemic seizures (HP:0002173)2.10700353
99Subaortic stenosis (HP:0001682)2.08700152
100Abnormality of the left ventricular outflow tract (HP:0011103)2.08700152
101Acute hepatic failure (HP:0006554)2.07450923
102Renal cortical cysts (HP:0000803)2.07291589
103Acute necrotizing encephalopathy (HP:0006965)2.07077349
104Abnormality of complement system (HP:0005339)2.06918814
105Pancreatic cysts (HP:0001737)2.05594508
106Reduced antithrombin III activity (HP:0001976)2.05553340
107Pheochromocytoma (HP:0002666)2.05225972
108Bundle branch block (HP:0011710)2.03499855
109Oligomenorrhea (HP:0000876)2.03071921
110Muscle fiber splitting (HP:0003555)2.02758380
111Methylmalonic aciduria (HP:0012120)2.02129973
112Enlarged kidneys (HP:0000105)2.01687371
113Vascular calcification (HP:0004934)1.99421225
114Abnormality of glycolysis (HP:0004366)1.99114029
115Irritability (HP:0000737)1.95438985
116Hyperventilation (HP:0002883)1.95366619
117Late onset (HP:0003584)1.94742987
118Methylmalonic acidemia (HP:0002912)1.93979998
119Abnormality of renal resorption (HP:0011038)1.93825255
120Papillary thyroid carcinoma (HP:0002895)1.93541447
121Abnormality of vitamin B metabolism (HP:0004340)1.93411105
122Hepatocellular carcinoma (HP:0001402)1.93273421
123Fibular aplasia (HP:0002990)1.92903768
124Lactic acidosis (HP:0003128)1.91378114
125Cerebral hemorrhage (HP:0001342)1.91119534
126EMG: myopathic abnormalities (HP:0003458)1.90140865
127Alkalosis (HP:0001948)1.90110328
128Syncope (HP:0001279)1.89868071
129Abnormal atrioventricular conduction (HP:0005150)1.89539427
130Amniotic constriction ring (HP:0009775)1.89414830
131Abnormality of placental membranes (HP:0011409)1.89414830
132Medial flaring of the eyebrow (HP:0010747)1.89375717
133Absent phalangeal crease (HP:0006109)1.89094386
134Thyroid carcinoma (HP:0002890)1.86781180
135Cerebral palsy (HP:0100021)1.86445339
136Termporal pattern (HP:0011008)1.84526903
137Insidious onset (HP:0003587)1.84526903
138Increased intramyocellular lipid droplets (HP:0012240)1.84294228
139Abnormality of the calf musculature (HP:0001430)1.83920319
140Respiratory failure (HP:0002878)1.83151846
141Ventricular tachycardia (HP:0004756)1.82959126
142Progressive macrocephaly (HP:0004481)1.82893428
143Renal Fanconi syndrome (HP:0001994)1.82570257
144Pancreatic fibrosis (HP:0100732)1.81740985
145Abnormality of vitamin metabolism (HP:0100508)1.80946728
146Muscular hypotonia of the trunk (HP:0008936)1.79802417
147Distal arthrogryposis (HP:0005684)1.79442477
148Intention tremor (HP:0002080)1.79427715
149Ulnar deviation of the wrist (HP:0003049)1.79092428
150Abnormality of the corticospinal tract (HP:0002492)1.78585668
151Drooling (HP:0002307)1.77651663
152Generalized hypopigmentation of hair (HP:0011358)1.77544125

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK4.78589987
2FRK4.08670907
3MAP4K24.04896136
4PDK33.49936964
5PDK43.49936964
6PHKG22.77152277
7PHKG12.77152277
8OBSCN2.76420649
9TRIM282.50848361
10BCR2.41715149
11MUSK2.40510192
12MAP2K42.36347060
13PINK12.33733756
14WNK42.31232876
15STK392.30871035
16INSRR2.26973813
17OXSR12.24731061
18LMTK22.22723413
19ERBB42.02660075
20ERBB32.00577498
21TTN1.90034696
22RPS6KA41.86720770
23PBK1.84093282
24PDK21.80377743
25CSNK1G31.79693600
26MAP3K131.64146063
27CSNK1G21.62372747
28STK38L1.61203407
29EIF2AK31.59288986
30WNK31.58242887
31CSNK1G11.55331344
32MAP3K41.54985199
33PLK21.54719242
34LATS11.53900915
35PIK3CA1.51234285
36EPHA41.50733003
37CSNK1A1L1.48724619
38SCYL21.43579556
39PIK3CG1.42665027
40ACVR1B1.41020164
41MAP3K71.39386578
42FGFR41.39065101
43BMPR1B1.38284029
44MAP3K91.37676718
45MAPKAPK31.35515915
46MAP2K71.34303102
47PRKAA21.33342158
48TAOK31.31641834
49MAPK131.30830035
50MAPK121.29448635
51MAP3K61.28396428
52GRK11.28051335
53MARK11.24713990
54KSR21.21131640
55SGK2231.15596034
56SGK4941.15596034
57CAMKK21.12957819
58TRPM71.12490697
59LIMK11.11473405
60SRPK11.10000982
61NEK11.08773723
62SIK11.07908034
63CCNB11.07281481
64EIF2AK11.06155138
65PKN11.05729964
66PRKD30.99493069
67SGK20.98550853
68PRKAA10.98199639
69MYLK0.96006811
70CAMK2D0.95306305
71NUAK10.92757767
72PDPK10.92510496
73BRSK20.92407211
74CAMK2A0.92271956
75KSR10.91918491
76TIE10.91622948
77ZAK0.90649599
78CAMK2G0.89805166
79SGK30.89151935
80FER0.87584950
81DAPK20.86812876
82PAK60.82167519
83PDK10.81108002
84MINK10.78170901
85MAPK110.76526297
86LATS20.72131227
87PAK30.70501081
88RPS6KA50.69637031
89PTK2B0.68960673
90WNK10.68104064
91PLK40.66416479
92EPHB10.64222749
93STK380.63844666
94RET0.62516690
95FLT30.61419944
96MAP2K60.60159915
97NTRK30.59695730
98PLK30.56811990
99ADRBK20.56691811
100PRKCH0.55754614
101SGK10.55403357
102PRKD10.54235183
103NEK90.54174652
104TRIB30.54167040
105JAK20.53631434
106PRKCG0.53418639
107MAP3K50.53405777
108DMPK0.52467223
109PRKACG0.52216887
110ABL20.51238653
111CDK30.50028994
112STK110.48474335
113PRKACA0.47870811
114CSNK1A10.47670781
115MAPK70.47612413
116TNIK0.47577126
117PRKCQ0.47097543
118PRKACB0.46930614
119RPS6KB10.45722063
120CASK0.45111044
121GRK70.42288293
122PRKCE0.40528845
123MARK20.40311710
124PRKG10.40122316
125MAP2K30.39952674
126CAMK2B0.39107241
127RAF10.38268386
128STK160.37901686
129CAMK10.37045970
130PRKCZ0.36595402
131PKN20.36088704
132ERN10.35216049
133MAP3K10.35214227
134MAP2K10.32798945
135NEK60.32503049
136MOS0.32032166
137FGFR30.31968031
138RPS6KA30.31010649
139AKT30.30660870
140PRKCA0.29558413
141MAP3K20.29126716
142MAPKAPK50.28905067
143BMPR20.28839432
144CAMK40.28670905
145MAP3K120.28551290
146STK30.27963281
147MST40.27711741
148NME10.26962337
149IGF1R0.25482441
150MAPK40.25404889
151AKT20.25279857
152DAPK10.25032255

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.58576911
2Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.43253748
3Propanoate metabolism_Homo sapiens_hsa006403.09203416
4Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.94236262
5Nitrogen metabolism_Homo sapiens_hsa009102.89846561
6Fatty acid degradation_Homo sapiens_hsa000712.88577965
7Butanoate metabolism_Homo sapiens_hsa006502.68210881
8Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.63096086
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.62283139
10Arginine biosynthesis_Homo sapiens_hsa002202.47420302
11Tryptophan metabolism_Homo sapiens_hsa003802.45143270
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.43844577
13Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.34297162
14Fatty acid metabolism_Homo sapiens_hsa012122.27829958
152-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.19665878
16Peroxisome_Homo sapiens_hsa041462.12609931
17Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.10726392
18Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.07550473
19Fatty acid elongation_Homo sapiens_hsa000621.96793069
20Pyruvate metabolism_Homo sapiens_hsa006201.94064734
21PPAR signaling pathway_Homo sapiens_hsa033201.84106431
22Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.82266044
23Complement and coagulation cascades_Homo sapiens_hsa046101.78855895
24beta-Alanine metabolism_Homo sapiens_hsa004101.78250388
25Histidine metabolism_Homo sapiens_hsa003401.72779531
26Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.64713691
27Carbon metabolism_Homo sapiens_hsa012001.57387718
28Protein export_Homo sapiens_hsa030601.51718166
29Pentose and glucuronate interconversions_Homo sapiens_hsa000401.50035737
30Sulfur metabolism_Homo sapiens_hsa009201.45632866
31Phenylalanine metabolism_Homo sapiens_hsa003601.39648776
32Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.39257891
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.32885470
34Bile secretion_Homo sapiens_hsa049761.31712040
35Retinol metabolism_Homo sapiens_hsa008301.28790651
36Chemical carcinogenesis_Homo sapiens_hsa052041.27350134
37Steroid hormone biosynthesis_Homo sapiens_hsa001401.26884830
38Tyrosine metabolism_Homo sapiens_hsa003501.25693878
39Starch and sucrose metabolism_Homo sapiens_hsa005001.22919577
40Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.22690994
41Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.22523809
42Selenocompound metabolism_Homo sapiens_hsa004501.22363985
43Biosynthesis of amino acids_Homo sapiens_hsa012301.19840403
44Cysteine and methionine metabolism_Homo sapiens_hsa002701.19741672
45Arginine and proline metabolism_Homo sapiens_hsa003301.17737289
46Vitamin B6 metabolism_Homo sapiens_hsa007501.16247823
47Glycosaminoglycan degradation_Homo sapiens_hsa005311.09346234
48Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.04428293
49ABC transporters_Homo sapiens_hsa020101.01400678
50Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.01040116
51Caffeine metabolism_Homo sapiens_hsa002320.96603842
52Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.94774751
53Glycerolipid metabolism_Homo sapiens_hsa005610.91714010
54Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.91145541
55Drug metabolism - other enzymes_Homo sapiens_hsa009830.90257216
56Folate biosynthesis_Homo sapiens_hsa007900.88460775
57Vitamin digestion and absorption_Homo sapiens_hsa049770.80012703
58Staphylococcus aureus infection_Homo sapiens_hsa051500.75252915
59Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.74422578
60Steroid biosynthesis_Homo sapiens_hsa001000.73127947
61Lysine degradation_Homo sapiens_hsa003100.72485348
62Cardiac muscle contraction_Homo sapiens_hsa042600.64862001
63Oxidative phosphorylation_Homo sapiens_hsa001900.62135993
64Ether lipid metabolism_Homo sapiens_hsa005650.62005104
65RNA degradation_Homo sapiens_hsa030180.60986111
66Fatty acid biosynthesis_Homo sapiens_hsa000610.58763413
67Maturity onset diabetes of the young_Homo sapiens_hsa049500.58645532
68Arachidonic acid metabolism_Homo sapiens_hsa005900.56654935
69Fat digestion and absorption_Homo sapiens_hsa049750.56034128
70Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.55899249
71Metabolic pathways_Homo sapiens_hsa011000.54744558
72Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50117661
73Sulfur relay system_Homo sapiens_hsa041220.49852826
74Pentose phosphate pathway_Homo sapiens_hsa000300.49297368
75Glucagon signaling pathway_Homo sapiens_hsa049220.49279806
76Parkinsons disease_Homo sapiens_hsa050120.45550279
77Phototransduction_Homo sapiens_hsa047440.44317859
78Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.43402778
79One carbon pool by folate_Homo sapiens_hsa006700.42145319
80Basal transcription factors_Homo sapiens_hsa030220.41296229
81Fructose and mannose metabolism_Homo sapiens_hsa000510.40105329
82Glutathione metabolism_Homo sapiens_hsa004800.38981035
83Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38977611
84Purine metabolism_Homo sapiens_hsa002300.38163582
85Glycerophospholipid metabolism_Homo sapiens_hsa005640.37886214
86Insulin resistance_Homo sapiens_hsa049310.37512720
87Lysosome_Homo sapiens_hsa041420.36973506
88Renin secretion_Homo sapiens_hsa049240.36672829
89Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36632405
90Alzheimers disease_Homo sapiens_hsa050100.36338413
91Cyanoamino acid metabolism_Homo sapiens_hsa004600.36268122
92Serotonergic synapse_Homo sapiens_hsa047260.35163017
93Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.34561350
94Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.34017902
95Adipocytokine signaling pathway_Homo sapiens_hsa049200.33340526
96Long-term depression_Homo sapiens_hsa047300.30366229
97alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.29325194
98Circadian rhythm_Homo sapiens_hsa047100.29068567
99Dilated cardiomyopathy_Homo sapiens_hsa054140.28250785
100Salivary secretion_Homo sapiens_hsa049700.27419188
101GABAergic synapse_Homo sapiens_hsa047270.26683253
102Ovarian steroidogenesis_Homo sapiens_hsa049130.26450681
103Oxytocin signaling pathway_Homo sapiens_hsa049210.24252056
104Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.23634722
105Insulin secretion_Homo sapiens_hsa049110.22425985
106Circadian entrainment_Homo sapiens_hsa047130.20811358
107Linoleic acid metabolism_Homo sapiens_hsa005910.19557224
108AMPK signaling pathway_Homo sapiens_hsa041520.18621983
109Dopaminergic synapse_Homo sapiens_hsa047280.18552625
110Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.16358868
111Insulin signaling pathway_Homo sapiens_hsa049100.15577662
112Huntingtons disease_Homo sapiens_hsa050160.14920810
113Regulation of autophagy_Homo sapiens_hsa041400.13052867
114Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.11606674
115Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.11196706
116Prion diseases_Homo sapiens_hsa050200.11074971
117Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.10680907
118Type II diabetes mellitus_Homo sapiens_hsa049300.07497987
119Galactose metabolism_Homo sapiens_hsa000520.07069985
120Glutamatergic synapse_Homo sapiens_hsa047240.06252469
121Calcium signaling pathway_Homo sapiens_hsa040200.05741771
122Collecting duct acid secretion_Homo sapiens_hsa049660.05726654
123cGMP-PKG signaling pathway_Homo sapiens_hsa040220.05456057

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