TCEANC

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1kynurenine metabolic process (GO:0070189)5.11042298
2tryptophan catabolic process (GO:0006569)4.82409785
3indole-containing compound catabolic process (GO:0042436)4.82409785
4indolalkylamine catabolic process (GO:0046218)4.82409785
5tryptophan metabolic process (GO:0006568)4.70169745
6indolalkylamine metabolic process (GO:0006586)4.63347922
7behavioral response to nicotine (GO:0035095)4.46434229
8piRNA metabolic process (GO:0034587)4.39793686
9ribosomal small subunit assembly (GO:0000028)4.26810280
10adaptation of signaling pathway (GO:0023058)3.96732760
11signal peptide processing (GO:0006465)3.81262323
12viral mRNA export from host cell nucleus (GO:0046784)3.75134185
13L-fucose catabolic process (GO:0042355)3.71021003
14fucose catabolic process (GO:0019317)3.71021003
15L-fucose metabolic process (GO:0042354)3.71021003
16protein K11-linked deubiquitination (GO:0035871)3.63522854
17cellular biogenic amine catabolic process (GO:0042402)3.62853858
18amine catabolic process (GO:0009310)3.62853858
19platelet dense granule organization (GO:0060155)3.61715669
20epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.49977433
21negative regulation of mast cell activation (GO:0033004)3.46608956
22activated T cell proliferation (GO:0050798)3.43441981
23detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.37270044
24response to pheromone (GO:0019236)3.30026013
25indole-containing compound metabolic process (GO:0042430)3.27474762
26meiotic chromosome segregation (GO:0045132)3.22621144
27poly(A)+ mRNA export from nucleus (GO:0016973)3.21438506
28tachykinin receptor signaling pathway (GO:0007217)3.20399007
29CENP-A containing nucleosome assembly (GO:0034080)3.15467259
30axoneme assembly (GO:0035082)3.11071265
31deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.11055806
32neural tube formation (GO:0001841)3.10627815
33metaphase plate congression (GO:0051310)3.10158946
34maturation of 5.8S rRNA (GO:0000460)3.07557403
35detection of light stimulus involved in sensory perception (GO:0050962)3.07389192
36detection of light stimulus involved in visual perception (GO:0050908)3.07389192
37RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.06739258
38glycerophospholipid catabolic process (GO:0046475)3.05477672
39DNA methylation involved in gamete generation (GO:0043046)3.03649247
40protein polyglutamylation (GO:0018095)3.01316638
41photoreceptor cell maintenance (GO:0045494)3.00741134
42somatic diversification of immune receptors via somatic mutation (GO:0002566)2.96792300
43somatic hypermutation of immunoglobulin genes (GO:0016446)2.96792300
44chromatin remodeling at centromere (GO:0031055)2.95061107
45regulation of nuclear cell cycle DNA replication (GO:0033262)2.94867876
46kinetochore organization (GO:0051383)2.94616502
47multicellular organism reproduction (GO:0032504)2.93805525
48telomere maintenance via semi-conservative replication (GO:0032201)2.92219724
49definitive hemopoiesis (GO:0060216)2.92089798
50establishment of chromosome localization (GO:0051303)2.91121942
51reflex (GO:0060004)2.91060413
52telomere maintenance via recombination (GO:0000722)2.91058364
53protein-cofactor linkage (GO:0018065)2.90178996
54regulation of action potential (GO:0098900)2.83797335
55water-soluble vitamin biosynthetic process (GO:0042364)2.82992640
56negative regulation of DNA-dependent DNA replication (GO:2000104)2.81543680
57mitotic recombination (GO:0006312)2.80908278
58cellular ketone body metabolic process (GO:0046950)2.79136438
59histone mRNA metabolic process (GO:0008334)2.78704775
60intra-S DNA damage checkpoint (GO:0031573)2.75954402
61preassembly of GPI anchor in ER membrane (GO:0016254)2.74758291
62mitotic metaphase plate congression (GO:0007080)2.73068119
63attachment of spindle microtubules to kinetochore (GO:0008608)2.68771627
64DNA strand elongation involved in DNA replication (GO:0006271)2.66760271
65kinetochore assembly (GO:0051382)2.65124370
66sulfation (GO:0051923)2.64795368
67respiratory chain complex IV assembly (GO:0008535)2.63778757
68tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.63511449
69RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.63511449
70DNA demethylation (GO:0080111)2.63149309
71purine nucleobase biosynthetic process (GO:0009113)2.62471916
72regulation of meiosis I (GO:0060631)2.61524058
73protein complex biogenesis (GO:0070271)2.61358762
74regulation of memory T cell differentiation (GO:0043380)2.60873902
75protein K6-linked ubiquitination (GO:0085020)2.60563370
76DNA replication checkpoint (GO:0000076)2.60561069
77DNA double-strand break processing (GO:0000729)2.60525269
78DNA catabolic process, exonucleolytic (GO:0000738)2.60112865
79negative regulation of telomere maintenance (GO:0032205)2.59877280
80intraciliary transport (GO:0042073)2.59710528
81benzene-containing compound metabolic process (GO:0042537)2.59464214
82resolution of meiotic recombination intermediates (GO:0000712)2.59230121
83doxorubicin metabolic process (GO:0044598)2.58547169
84daunorubicin metabolic process (GO:0044597)2.58547169
85polyketide metabolic process (GO:0030638)2.58547169
86epithelial cilium movement (GO:0003351)2.58499636
87DNA topological change (GO:0006265)2.57985589
88maturation of SSU-rRNA (GO:0030490)2.57631877
89telomere organization (GO:0032200)2.57184734
90nucleobase biosynthetic process (GO:0046112)2.56878335
91DNA strand elongation (GO:0022616)2.56262804
92aromatic amino acid family catabolic process (GO:0009074)2.56219329
93IMP biosynthetic process (GO:0006188)2.55281527
94rRNA methylation (GO:0031167)2.53159838
95DNA replication-independent nucleosome assembly (GO:0006336)2.52931913
96DNA replication-independent nucleosome organization (GO:0034724)2.52931913
97telomere maintenance (GO:0000723)2.52715523
98male meiosis I (GO:0007141)2.52574259
99synapsis (GO:0007129)2.51282110
100mismatch repair (GO:0006298)2.50735577
101dopamine transport (GO:0015872)2.50661002
102reciprocal meiotic recombination (GO:0007131)2.50635536
103reciprocal DNA recombination (GO:0035825)2.50635536
104histone H4-K12 acetylation (GO:0043983)2.49751356
105DNA integration (GO:0015074)2.49736059
106protein deneddylation (GO:0000338)2.49631925
107deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.48822859
108replication fork processing (GO:0031297)2.48753567
109rRNA modification (GO:0000154)2.46694454
110rRNA catabolic process (GO:0016075)2.46529420
111positive regulation of cAMP-mediated signaling (GO:0043950)2.45720402
112nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.45665153
113ketone body metabolic process (GO:1902224)2.45513497
114pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.45274847
115gamma-aminobutyric acid transport (GO:0015812)2.45037067
116neuronal action potential propagation (GO:0019227)2.44931098
117G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.43798345
118ubiquinone biosynthetic process (GO:0006744)2.43496971
119kidney morphogenesis (GO:0060993)2.43319388
120negative regulation of phagocytosis (GO:0050765)2.42830466
121retinal cone cell development (GO:0046549)2.41574088
122auditory receptor cell stereocilium organization (GO:0060088)2.41553235
123positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.41453677
124positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.41453677
125positive regulation of mitotic sister chromatid separation (GO:1901970)2.41453677
126adenosine metabolic process (GO:0046085)2.40743461
127histone mRNA catabolic process (GO:0071044)2.39948509
128mitochondrial respiratory chain complex assembly (GO:0033108)2.39381741
129regulation of hexokinase activity (GO:1903299)2.39059162
130regulation of glucokinase activity (GO:0033131)2.39059162
131exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.38967575
132protein neddylation (GO:0045116)2.38374552
133double-strand break repair via homologous recombination (GO:0000724)2.37708699
134recombinational repair (GO:0000725)2.37503239
135dosage compensation (GO:0007549)2.37125152
136transcription-coupled nucleotide-excision repair (GO:0006283)2.37056209
137protein localization to cilium (GO:0061512)2.36698470
138DNA replication initiation (GO:0006270)2.36167508
139S-adenosylmethionine metabolic process (GO:0046500)2.36166846
140mannosylation (GO:0097502)2.36044088
141regulation of double-strand break repair via homologous recombination (GO:0010569)2.35851203
142oxidative demethylation (GO:0070989)2.35673119
143hepatocyte apoptotic process (GO:0097284)2.35148062
144telomere maintenance via telomere lengthening (GO:0010833)2.35016784
145multi-organism intracellular transport (GO:1902583)2.34987928
146transport of virus (GO:0046794)2.34987928
147intracellular transport of virus (GO:0075733)2.34987928
148multi-organism transport (GO:0044766)2.34987928
149multi-organism localization (GO:1902579)2.34987928
150aromatic amino acid family metabolic process (GO:0009072)2.34548516
151cullin deneddylation (GO:0010388)2.34038339
152negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254)2.33951517
153DNA damage response, signal transduction resulting in transcription (GO:0042772)2.33757591
154negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)2.33257229
155histamine secretion (GO:0001821)2.33212935
156regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.32584892
157male meiosis (GO:0007140)2.32577871
158regulation of cilium movement (GO:0003352)2.31348907
159primary amino compound metabolic process (GO:1901160)2.31336292
160heart contraction (GO:0060047)2.31315281
161heart process (GO:0003015)2.31315281
162DNA deamination (GO:0045006)2.30701660
163centriole replication (GO:0007099)2.30405835
164viral protein processing (GO:0019082)2.30133040
165mitochondrial respiratory chain complex I assembly (GO:0032981)2.29402407
166NADH dehydrogenase complex assembly (GO:0010257)2.29402407
167mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.29402407
168tRNA methylation (GO:0030488)2.29239382
169phosphatidylinositol acyl-chain remodeling (GO:0036149)2.29226379
170positive regulation of mRNA catabolic process (GO:0061014)2.29103418
171regulation of telomere maintenance via telomerase (GO:0032210)2.28139058
172GPI anchor biosynthetic process (GO:0006506)2.27898921
173maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.27828244
174regulation of DNA endoreduplication (GO:0032875)2.27740512
175nucleotide-excision repair, DNA gap filling (GO:0006297)2.27547555
176postreplication repair (GO:0006301)2.27479265
177prenylation (GO:0097354)2.27047081
178protein prenylation (GO:0018342)2.27047081
179establishment of protein localization to Golgi (GO:0072600)2.26284124
180ribosomal small subunit biogenesis (GO:0042274)2.26238009
181auditory receptor cell differentiation (GO:0042491)2.25552873
182negative regulation of transcription regulatory region DNA binding (GO:2000678)2.25320613
183mRNA export from nucleus (GO:0006406)2.25245263
184cytochrome complex assembly (GO:0017004)2.24831666
185neuronal action potential (GO:0019228)2.24468435
186ER overload response (GO:0006983)2.24024479
187negative regulation of synaptic transmission, GABAergic (GO:0032229)2.22690173
188organelle membrane fusion (GO:0090174)2.22586535

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.90936410
2ELF1_17652178_ChIP-ChIP_JURKAT_Human3.99430469
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.90430408
4ZNF274_21170338_ChIP-Seq_K562_Hela3.65022530
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.30186233
6VDR_22108803_ChIP-Seq_LS180_Human3.29024769
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.23026399
8GABP_17652178_ChIP-ChIP_JURKAT_Human3.09649802
9EZH2_22144423_ChIP-Seq_EOC_Human3.04697478
10GBX2_23144817_ChIP-Seq_PC3_Human2.97062072
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.93395602
12E2F4_17652178_ChIP-ChIP_JURKAT_Human2.89457299
13RBPJ_22232070_ChIP-Seq_NCS_Mouse2.88516652
14MYC_18555785_ChIP-Seq_MESCs_Mouse2.82402106
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.74698549
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.58699771
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.57937112
18FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.56638147
19ELK1_19687146_ChIP-ChIP_HELA_Human2.55604234
20TP63_19390658_ChIP-ChIP_HaCaT_Human2.55505404
21HOXB4_20404135_ChIP-ChIP_EML_Mouse2.47597146
22ZFP57_27257070_Chip-Seq_ESCs_Mouse2.46824271
23POU3F2_20337985_ChIP-ChIP_501MEL_Human2.46658307
24VDR_23849224_ChIP-Seq_CD4+_Human2.38234669
25SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.36178517
26FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.35583345
27HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.33160727
28PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.29492382
29CREB1_15753290_ChIP-ChIP_HEK293T_Human2.27285213
30IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.21822003
31SRF_21415370_ChIP-Seq_HL-1_Mouse2.21230720
32MYC_19030024_ChIP-ChIP_MESCs_Mouse2.17156896
33NELFA_20434984_ChIP-Seq_ESCs_Mouse2.16190273
34HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.12638188
35ETS1_20019798_ChIP-Seq_JURKAT_Human2.06955826
36NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.06845048
37FOXP3_21729870_ChIP-Seq_TREG_Human2.05750471
38CTBP2_25329375_ChIP-Seq_LNCAP_Human2.05205758
39ER_23166858_ChIP-Seq_MCF-7_Human2.01171311
40FUS_26573619_Chip-Seq_HEK293_Human1.98457088
41MYC_18358816_ChIP-ChIP_MESCs_Mouse1.97796521
42MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.95917288
43GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.92303886
44NOTCH1_21737748_ChIP-Seq_TLL_Human1.91323729
45TAF15_26573619_Chip-Seq_HEK293_Human1.90962073
46P300_19829295_ChIP-Seq_ESCs_Human1.89326574
47FOXM1_23109430_ChIP-Seq_U2OS_Human1.88091909
48ERG_20887958_ChIP-Seq_HPC-7_Mouse1.86267205
49CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.84759870
50EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.83562131
51IRF8_22096565_ChIP-ChIP_GC-B_Human1.79998941
52FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.79594190
53EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.78738530
54E2F1_18555785_ChIP-Seq_MESCs_Mouse1.78092784
55SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.76967367
56CTBP1_25329375_ChIP-Seq_LNCAP_Human1.76374268
57E2F1_21310950_ChIP-Seq_MCF-7_Human1.75696300
58MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.73277985
59PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.72988222
60PADI4_21655091_ChIP-ChIP_MCF-7_Human1.70955486
61BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.69382358
62KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.68604833
63AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.66919742
64YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.65581497
65TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.64374061
66SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.62965593
67MYC_19079543_ChIP-ChIP_MESCs_Mouse1.59704688
68IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.57969645
69CBP_20019798_ChIP-Seq_JUKART_Human1.57969645
70MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.57758521
71THAP11_20581084_ChIP-Seq_MESCs_Mouse1.57199737
72UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.56550913
73XRN2_22483619_ChIP-Seq_HELA_Human1.56181832
74BCAT_22108803_ChIP-Seq_LS180_Human1.54935914
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.54841561
76SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.53590808
77DCP1A_22483619_ChIP-Seq_HELA_Human1.51011596
78GATA1_22025678_ChIP-Seq_K562_Human1.50736686
79TTF2_22483619_ChIP-Seq_HELA_Human1.49510204
80TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.49455418
81STAT3_23295773_ChIP-Seq_U87_Human1.48851995
82TP53_22573176_ChIP-Seq_HFKS_Human1.46427425
83GABP_19822575_ChIP-Seq_HepG2_Human1.43263549
84CIITA_25753668_ChIP-Seq_RAJI_Human1.42185484
85MYCN_18555785_ChIP-Seq_MESCs_Mouse1.41380283
86EZH2_27294783_Chip-Seq_NPCs_Mouse1.40451462
87TCF4_23295773_ChIP-Seq_U87_Human1.38974713
88MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.38269795
89PCGF2_27294783_Chip-Seq_NPCs_Mouse1.38102619
90SMAD4_21799915_ChIP-Seq_A2780_Human1.37834427
91FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.37388172
92SUZ12_27294783_Chip-Seq_NPCs_Mouse1.36420328
93TFEB_21752829_ChIP-Seq_HELA_Human1.36384604
94DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.36103662
95PIAS1_25552417_ChIP-Seq_VCAP_Human1.35447557
96IRF1_19129219_ChIP-ChIP_H3396_Human1.34664954
97FOXA1_27270436_Chip-Seq_PROSTATE_Human1.34336779
98FOXA1_25329375_ChIP-Seq_VCAP_Human1.34336779
99STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.33576091
100FLI1_27457419_Chip-Seq_LIVER_Mouse1.32976012
101SOX2_19829295_ChIP-Seq_ESCs_Human1.32405245
102NANOG_19829295_ChIP-Seq_ESCs_Human1.32405245
103AR_25329375_ChIP-Seq_VCAP_Human1.30311471
104NFE2_27457419_Chip-Seq_LIVER_Mouse1.30003518
105YY1_21170310_ChIP-Seq_MESCs_Mouse1.29590565
106RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.29294836
107GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.28808206
108PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.28137298
109EGR1_23403033_ChIP-Seq_LIVER_Mouse1.27953776
110PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.27026298
111NR3C1_21868756_ChIP-Seq_MCF10A_Human1.26552269
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26514061
113POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.26514061
114FLI1_21867929_ChIP-Seq_TH2_Mouse1.25328948
115ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.24546321
116TCF4_22108803_ChIP-Seq_LS180_Human1.24117647
117CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.23210706
118GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.21974705
119KLF5_20875108_ChIP-Seq_MESCs_Mouse1.21847210
120CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.21639532
121FOXA1_21572438_ChIP-Seq_LNCaP_Human1.21389646
122SCL_19346495_ChIP-Seq_HPC-7_Human1.21055777
123ETV2_25802403_ChIP-Seq_MESCs_Mouse1.21016144
124CRX_20693478_ChIP-Seq_RETINA_Mouse1.19791675
125PRDM14_20953172_ChIP-Seq_ESCs_Human1.19268779
126* SPI1_23547873_ChIP-Seq_NB4_Human1.18745509
127ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.18552073
128SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.18159445
129EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.17836443
130EWS_26573619_Chip-Seq_HEK293_Human1.17810257
131SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.17529740
132TOP2B_26459242_ChIP-Seq_MCF-7_Human1.17361293
133NCOR_22424771_ChIP-Seq_293T_Human1.16488143
134ZFX_18555785_ChIP-Seq_MESCs_Mouse1.16131586
135PCGF2_27294783_Chip-Seq_ESCs_Mouse1.16086556
136GATA3_26560356_Chip-Seq_TH2_Human1.16043205
137GATA3_21878914_ChIP-Seq_MCF-7_Human1.15432396
138SMAD3_21741376_ChIP-Seq_EPCs_Human1.14614365
139RUNX2_22187159_ChIP-Seq_PCA_Human1.12632091
140POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.11923507
141CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.11868911
142ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.11681258
143AR_20517297_ChIP-Seq_VCAP_Human1.08040163
144SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.07803085
145CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.06719107
146MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.05909760
147SOX2_18555785_ChIP-Seq_MESCs_Mouse1.05310902
148AUTS2_25519132_ChIP-Seq_293T-REX_Human1.04695546
149IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.04589468
150EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.04184663
151OCT4_21477851_ChIP-Seq_ESCs_Mouse1.03737284
152NANOG_18555785_Chip-Seq_ESCs_Mouse1.03623314
153AR_21572438_ChIP-Seq_LNCaP_Human1.03375167
154OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03152230
155E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.03004452
156CDX2_22108803_ChIP-Seq_LS180_Human1.02551189
157SMAD4_21741376_ChIP-Seq_EPCs_Human1.02542832
158IRF8_21731497_ChIP-ChIP_J774_Mouse1.02341358
159MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.97117529
160AR_21909140_ChIP-Seq_LNCAP_Human0.95883100
161POU5F1_16153702_ChIP-ChIP_HESCs_Human0.95504337
162EGR1_19374776_ChIP-ChIP_THP-1_Human0.95238278
163MYC_18940864_ChIP-ChIP_HL60_Human0.95168680
164BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.95066312
165E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.93995563
166STAT4_19710469_ChIP-ChIP_TH1__Mouse0.93842329
167FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.92060632
168NANOG_18555785_ChIP-Seq_MESCs_Mouse0.92053404
169NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.90617420
170POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.89159250
171SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.88782964
172KDM5A_27292631_Chip-Seq_BREAST_Human0.88285837
173IGF1R_20145208_ChIP-Seq_DFB_Human0.87420360
174ELK1_22589737_ChIP-Seq_MCF10A_Human0.85192148
175SALL1_21062744_ChIP-ChIP_HESCs_Human0.81076057
176SOX17_20123909_ChIP-Seq_XEN_Mouse0.80621843
177CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.78061881
178CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.77673601

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000372_irregular_coat_pigmentation3.22458048
2MP0008058_abnormal_DNA_repair3.14002434
3MP0003693_abnormal_embryo_hatching3.06238728
4MP0003646_muscle_fatigue3.01053712
5MP0008057_abnormal_DNA_replication2.78684947
6MP0003195_calcinosis2.77413986
7MP0002132_abnormal_respiratory_system2.74432159
8MP0002877_abnormal_melanocyte_morpholog2.72699123
9MP0010094_abnormal_chromosome_stability2.72555603
10MP0002102_abnormal_ear_morphology2.54839025
11MP0005551_abnormal_eye_electrophysiolog2.43561379
12MP0000569_abnormal_digit_pigmentation2.42380324
13MP0003077_abnormal_cell_cycle2.37719416
14MP0003121_genomic_imprinting2.36816052
15MP0008007_abnormal_cellular_replicative2.33596851
16MP0009697_abnormal_copulation2.26615025
17MP0006054_spinal_hemorrhage2.11695026
18MP0002009_preneoplasia2.10449775
19MP0003123_paternal_imprinting2.08298813
20MP0002837_dystrophic_cardiac_calcinosis2.05734042
21MP0001968_abnormal_touch/_nociception2.05429689
22MP0005645_abnormal_hypothalamus_physiol2.03596037
23MP0002876_abnormal_thyroid_physiology2.01267357
24MP0008789_abnormal_olfactory_epithelium2.01126181
25MP0008872_abnormal_physiological_respon1.99471581
26MP0002163_abnormal_gland_morphology1.94493881
27MP0004957_abnormal_blastocyst_morpholog1.91669376
28MP0002396_abnormal_hematopoietic_system1.90200050
29MP0003941_abnormal_skin_development1.89606097
30MP0002638_abnormal_pupillary_reflex1.89051845
31MP0002138_abnormal_hepatobiliary_system1.86396472
32MP0003786_premature_aging1.84118679
33MP0005253_abnormal_eye_physiology1.77185981
34MP0004142_abnormal_muscle_tone1.74640323
35MP0005646_abnormal_pituitary_gland1.71564137
36MP0005379_endocrine/exocrine_gland_phen1.71553197
37MP0008995_early_reproductive_senescence1.69651832
38MP0003011_delayed_dark_adaptation1.67489329
39MP0003111_abnormal_nucleus_morphology1.65390659
40MP0003136_yellow_coat_color1.65089475
41MP0002938_white_spotting1.63893151
42MP0006292_abnormal_olfactory_placode1.62609377
43MP0009046_muscle_twitch1.57700198
44MP0005451_abnormal_body_composition1.56080794
45MP0005084_abnormal_gallbladder_morpholo1.54826855
46MP0004782_abnormal_surfactant_physiolog1.53783587
47MP0003763_abnormal_thymus_physiology1.52464707
48MP0009745_abnormal_behavioral_response1.51115649
49MP0005671_abnormal_response_to1.50916239
50MP0002736_abnormal_nociception_after1.50153442
51MP0003252_abnormal_bile_duct1.49882778
52MP0000678_abnormal_parathyroid_gland1.49564313
53MP0002095_abnormal_skin_pigmentation1.46518714
54MP0003122_maternal_imprinting1.46299908
55MP0002272_abnormal_nervous_system1.44681099
56MP0003943_abnormal_hepatobiliary_system1.43999552
57MP0001501_abnormal_sleep_pattern1.43681185
58MP0008875_abnormal_xenobiotic_pharmacok1.43399836
59MP0000015_abnormal_ear_pigmentation1.43052049
60MP0003880_abnormal_central_pattern1.40246866
61MP0000427_abnormal_hair_cycle1.39353417
62MP0005075_abnormal_melanosome_morpholog1.35859607
63MP0001188_hyperpigmentation1.35265995
64MP0004145_abnormal_muscle_electrophysio1.35098893
65MP0003718_maternal_effect1.34963220
66MP0006276_abnormal_autonomic_nervous1.32482516
67MP0004043_abnormal_pH_regulation1.32084081
68MP0002928_abnormal_bile_duct1.31856154
69MP0004147_increased_porphyrin_level1.31539549
70MP0005408_hypopigmentation1.30543361
71MP0000631_abnormal_neuroendocrine_gland1.28441142
72MP0004885_abnormal_endolymph1.26436487
73MP0000490_abnormal_crypts_of1.25231234
74MP0003787_abnormal_imprinting1.24085570
75MP0005410_abnormal_fertilization1.22092024
76MP0001293_anophthalmia1.21767140
77MP0001485_abnormal_pinna_reflex1.21320978
78MP0006072_abnormal_retinal_apoptosis1.19640454
79MP0008877_abnormal_DNA_methylation1.17762796
80MP0001986_abnormal_taste_sensitivity1.17355156
81MP0004808_abnormal_hematopoietic_stem1.17150021
82MP0009333_abnormal_splenocyte_physiolog1.16554638
83MP0003186_abnormal_redox_activity1.15551183
84MP0010307_abnormal_tumor_latency1.14263219
85MP0001835_abnormal_antigen_presentation1.12824130
86MP0003890_abnormal_embryonic-extraembry1.10492253
87MP0001919_abnormal_reproductive_system1.09507431
88MP0002398_abnormal_bone_marrow1.09505258
89MP0005394_taste/olfaction_phenotype1.08948580
90MP0005499_abnormal_olfactory_system1.08948580
91MP0002653_abnormal_ependyma_morphology1.07517830
92MP0001486_abnormal_startle_reflex1.07359392
93MP0001186_pigmentation_phenotype1.06365194
94MP0010386_abnormal_urinary_bladder1.05887283
95MP0008932_abnormal_embryonic_tissue1.05419138
96MP0004742_abnormal_vestibular_system1.05038656
97MP0001119_abnormal_female_reproductive1.04806910
98MP0002735_abnormal_chemical_nociception1.04774791
99MP0000566_synostosis1.03465105
100MP0009764_decreased_sensitivity_to1.03457505
101MP0005171_absent_coat_pigmentation0.99987066
102MP0002733_abnormal_thermal_nociception0.99064517
103MP0002234_abnormal_pharynx_morphology0.98413058
104MP0000313_abnormal_cell_death0.98406241
105MP0001764_abnormal_homeostasis0.98018223
106MP0002067_abnormal_sensory_capabilities0.97963966
107MP0008775_abnormal_heart_ventricle0.97750491
108MP0001970_abnormal_pain_threshold0.97637475
109MP0002277_abnormal_respiratory_mucosa0.97224080
110MP0004215_abnormal_myocardial_fiber0.96759366
111MP0001502_abnormal_circadian_rhythm0.96026867
112MP0000613_abnormal_salivary_gland0.95986320
113MP0005085_abnormal_gallbladder_physiolo0.95818187
114MP0000703_abnormal_thymus_morphology0.95662067
115MP0001853_heart_inflammation0.95256046
116MP0001545_abnormal_hematopoietic_system0.93751351
117MP0005397_hematopoietic_system_phenotyp0.93751351
118MP0002166_altered_tumor_susceptibility0.93053609
119MP0000689_abnormal_spleen_morphology0.92674975
120MP0010329_abnormal_lipoprotein_level0.91495222
121MP0005174_abnormal_tail_pigmentation0.90664647
122MP0006035_abnormal_mitochondrial_morpho0.90457407
123MP0000350_abnormal_cell_proliferation0.89976185
124MP0002722_abnormal_immune_system0.88811106
125MP0002572_abnormal_emotion/affect_behav0.88411090
126MP0002064_seizures0.88292868
127MP0005083_abnormal_biliary_tract0.88081589
128MP0003942_abnormal_urinary_system0.86520507
129MP0002019_abnormal_tumor_incidence0.85738018
130MP0005220_abnormal_exocrine_pancreas0.85703997
131MP0001800_abnormal_humoral_immune0.85501843
132MP0001905_abnormal_dopamine_level0.85451737
133MP0002006_tumorigenesis0.85205456
134MP0002148_abnormal_hypersensitivity_rea0.84910038
135MP0001929_abnormal_gametogenesis0.84177362
136MP0002098_abnormal_vibrissa_morphology0.83239675
137MP0005167_abnormal_blood-brain_barrier0.83059272
138MP0003567_abnormal_fetal_cardiomyocyte0.82971220
139MP0006036_abnormal_mitochondrial_physio0.82670172
140MP0002420_abnormal_adaptive_immunity0.82644747
141MP0004924_abnormal_behavior0.81495917
142MP0005386_behavior/neurological_phenoty0.81495917
143MP0003698_abnormal_male_reproductive0.81106358
144MP0002693_abnormal_pancreas_physiology0.80572713
145MP0002229_neurodegeneration0.80349284
146MP0000049_abnormal_middle_ear0.78848709
147MP0001819_abnormal_immune_cell0.78701172
148MP0010352_gastrointestinal_tract_polyps0.78386290
149MP0002405_respiratory_system_inflammati0.78361662
150MP0005389_reproductive_system_phenotype0.78228488
151MP0002063_abnormal_learning/memory/cond0.77902611
152MP0002429_abnormal_blood_cell0.77089911
153MP0002452_abnormal_antigen_presenting0.77057569
154MP0000716_abnormal_immune_system0.76880392
155MP0005266_abnormal_metabolism0.76284655
156MP0009785_altered_susceptibility_to0.75999060
157MP0000681_abnormal_thyroid_gland0.75993484
158MP0002075_abnormal_coat/hair_pigmentati0.75209803
159MP0002751_abnormal_autonomic_nervous0.74686963
160MP0000230_abnormal_systemic_arterial0.74613914
161MP0001286_abnormal_eye_development0.74430685
162MP0001984_abnormal_olfaction0.73556335
163MP0005332_abnormal_amino_acid0.73121389
164MP0002210_abnormal_sex_determination0.71535067
165MP0002557_abnormal_social/conspecific_i0.70215265
166MP0003656_abnormal_erythrocyte_physiolo0.69844044
167MP0004130_abnormal_muscle_cell0.69807099
168MP0002249_abnormal_larynx_morphology0.69665533
169MP0000653_abnormal_sex_gland0.68426064
170MP0002723_abnormal_immune_serum0.68282380
171MP0001730_embryonic_growth_arrest0.67679263
172MP0003635_abnormal_synaptic_transmissio0.66486402
173MP0003984_embryonic_growth_retardation0.66305948
174MP0000516_abnormal_urinary_system0.66283505
175MP0000383_abnormal_hair_follicle0.66202381

Predicted human phenotypes

RankGene SetZ-score
1Hypothermia (HP:0002045)4.06084822
2Abnormality of cochlea (HP:0000375)3.93635148
311 pairs of ribs (HP:0000878)3.73865043
4Congenital stationary night blindness (HP:0007642)3.70215526
5Chromosomal breakage induced by crosslinking agents (HP:0003221)3.58792638
6Chromsome breakage (HP:0040012)3.56556881
7Abolished electroretinogram (ERG) (HP:0000550)3.37627319
8Aplastic anemia (HP:0001915)3.26684754
9Nephronophthisis (HP:0000090)3.23811256
10Pendular nystagmus (HP:0012043)3.14611086
11Abnormal biliary tract physiology (HP:0012439)3.14235630
12Bile duct proliferation (HP:0001408)3.14235630
13True hermaphroditism (HP:0010459)3.07914692
14Hyperventilation (HP:0002883)3.07062863
15Nephroblastoma (Wilms tumor) (HP:0002667)2.94627541
16Type I transferrin isoform profile (HP:0003642)2.94577082
17Bifid tongue (HP:0010297)2.92469722
18Abnormality of the renal medulla (HP:0100957)2.89359995
19Attenuation of retinal blood vessels (HP:0007843)2.82916598
20Intestinal atresia (HP:0011100)2.82365877
21Chronic hepatic failure (HP:0100626)2.82071975
22Abnormal rod and cone electroretinograms (HP:0008323)2.80460069
23Type II lissencephaly (HP:0007260)2.72136893
24Tubular atrophy (HP:0000092)2.70272801
25Colon cancer (HP:0003003)2.69928599
26Embryonal renal neoplasm (HP:0011794)2.69715431
27Absent eyebrow (HP:0002223)2.67625110
28Abnormality of B cell number (HP:0010975)2.67157390
29B lymphocytopenia (HP:0010976)2.67157390
30Abnormal drinking behavior (HP:0030082)2.67127760
31Polydipsia (HP:0001959)2.67127760
32Gaze-evoked nystagmus (HP:0000640)2.60882144
33Morphological abnormality of the inner ear (HP:0011390)2.60037664
34Stomatitis (HP:0010280)2.57091201
35Renal cortical cysts (HP:0000803)2.53718066
36Thyroiditis (HP:0100646)2.52318043
37Cystic liver disease (HP:0006706)2.50234107
38IgM deficiency (HP:0002850)2.47690348
393-Methylglutaconic aciduria (HP:0003535)2.46374253
40Abnormal lung lobation (HP:0002101)2.44776238
41Osteomalacia (HP:0002749)2.41448490
42Generalized aminoaciduria (HP:0002909)2.41182434
43Aplasia/Hypoplasia of the uvula (HP:0010293)2.41082498
44Decreased central vision (HP:0007663)2.41029236
45Decreased electroretinogram (ERG) amplitude (HP:0000654)2.40164258
46Reticulocytopenia (HP:0001896)2.39519291
47Medial flaring of the eyebrow (HP:0010747)2.37724762
48Abnormality of chromosome stability (HP:0003220)2.37442086
49Abnormal protein glycosylation (HP:0012346)2.37104936
50Abnormal glycosylation (HP:0012345)2.37104936
51Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.37104936
52Abnormal protein N-linked glycosylation (HP:0012347)2.37104936
53Hemiparesis (HP:0001269)2.35067977
54Medulloblastoma (HP:0002885)2.34871404
55Pancreatic fibrosis (HP:0100732)2.31987253
56Agitation (HP:0000713)2.25839532
57Meckel diverticulum (HP:0002245)2.25289549
58Abnormality of the heme biosynthetic pathway (HP:0010472)2.22743675
59Pancreatic cysts (HP:0001737)2.22122332
60Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.21538801
61Abnormality of alanine metabolism (HP:0010916)2.21538801
62Hyperalaninemia (HP:0003348)2.21538801
63Pancreatic islet-cell hyperplasia (HP:0004510)2.20881605
64Abnormality of the labia minora (HP:0012880)2.19515844
65Abnormality of the ileum (HP:0001549)2.19088597
66Methylmalonic acidemia (HP:0002912)2.18012397
67Focal motor seizures (HP:0011153)2.17859814
68Absent/shortened dynein arms (HP:0200106)2.15436695
69Dynein arm defect of respiratory motile cilia (HP:0012255)2.15436695
70Progressive inability to walk (HP:0002505)2.14522762
71Papillary thyroid carcinoma (HP:0002895)2.13795990
72Optic nerve coloboma (HP:0000588)2.10256242
73Hepatoblastoma (HP:0002884)2.09520450
74Increased corneal curvature (HP:0100692)2.09508763
75Keratoconus (HP:0000563)2.09508763
76Abnormality of the preputium (HP:0100587)2.08327901
77Aplasia/Hypoplasia of the tibia (HP:0005772)2.08171977
78Myelodysplasia (HP:0002863)2.07764649
79Sclerocornea (HP:0000647)2.05957895
80Genetic anticipation (HP:0003743)2.05739404
81Inability to walk (HP:0002540)2.04126931
82IgG deficiency (HP:0004315)2.03450325
83Congenital hepatic fibrosis (HP:0002612)2.00943543
84Cerebellar dysplasia (HP:0007033)2.00450254
85Male pseudohermaphroditism (HP:0000037)1.99792127
86Neoplasm of the adrenal gland (HP:0100631)1.99633855
87Febrile seizures (HP:0002373)1.98718903
88Bone marrow hypocellularity (HP:0005528)1.98087622
89Methylmalonic aciduria (HP:0012120)1.97979378
90Lymphoma (HP:0002665)1.97022962
91Polyuria (HP:0000103)1.96001019
92Fair hair (HP:0002286)1.95871858
93Abnormality of the renal cortex (HP:0011035)1.95837270
94Lissencephaly (HP:0001339)1.95219880
95Abnormality of the renal collecting system (HP:0004742)1.94703978
96Bony spicule pigmentary retinopathy (HP:0007737)1.94242217
97Enlarged kidneys (HP:0000105)1.93884723
98Abnormality of DNA repair (HP:0003254)1.92968828
99Neoplasm of the adrenal cortex (HP:0100641)1.90676487
100Long clavicles (HP:0000890)1.89884074
101Hypochromic microcytic anemia (HP:0004840)1.89691310
102Thrombocytosis (HP:0001894)1.89120772
103Abnormal pancreas size (HP:0012094)1.88826502
104Progressive cerebellar ataxia (HP:0002073)1.88301911
105Hypoplasia of the fovea (HP:0007750)1.87817780
106Aplasia/Hypoplasia of the fovea (HP:0008060)1.87817780
107Duplicated collecting system (HP:0000081)1.87419129
108Missing ribs (HP:0000921)1.85947046
109Dialeptic seizures (HP:0011146)1.85705830
110Abnormal respiratory epithelium morphology (HP:0012253)1.84989138
111Abnormal respiratory motile cilium morphology (HP:0005938)1.84989138
112Absent rod-and cone-mediated responses on ERG (HP:0007688)1.84895610
113Ketoacidosis (HP:0001993)1.84667995
114Premature graying of hair (HP:0002216)1.84655307
115Increased CSF lactate (HP:0002490)1.84150721
116Severe combined immunodeficiency (HP:0004430)1.83752720
117Furrowed tongue (HP:0000221)1.81326429
118Pachygyria (HP:0001302)1.81231661
119Focal seizures (HP:0007359)1.80638813
120Aplasia/Hypoplasia of the tongue (HP:0010295)1.80266473
121Tinnitus (HP:0000360)1.80225681
122Ketosis (HP:0001946)1.78141135
123Abnormality of the prostate (HP:0008775)1.77666500
124Abnormal biliary tract morphology (HP:0012440)1.77463615
125Anencephaly (HP:0002323)1.77080583
126Hepatic necrosis (HP:0002605)1.76059660
127Neoplasm of the thyroid gland (HP:0100031)1.75444973
128Aplasia/Hypoplasia of the spleen (HP:0010451)1.74459756
129Embryonal neoplasm (HP:0002898)1.74244168
130Large for gestational age (HP:0001520)1.74083560
131Broad-based gait (HP:0002136)1.73949711
132Abnormality of macular pigmentation (HP:0008002)1.72796613
133White forelock (HP:0002211)1.72195493
134Xerostomia (HP:0000217)1.71088585
135Birth length less than 3rd percentile (HP:0003561)1.70980266
136Concave nail (HP:0001598)1.70734295
137Stomach cancer (HP:0012126)1.70183332
138Asplenia (HP:0001746)1.69745112
139Abnormality of incisor morphology (HP:0011063)1.69187382
140Tubulointerstitial abnormality (HP:0001969)1.68528091
141Hypoproteinemia (HP:0003075)1.68327770
142Absent speech (HP:0001344)1.68302156
143Clubbing of toes (HP:0100760)1.68143424
144Mitochondrial inheritance (HP:0001427)1.67917296
145Alveolar cell carcinoma (HP:0006519)1.67888976
146Chorioretinal atrophy (HP:0000533)1.67839614
147Patchy hypopigmentation of hair (HP:0011365)1.67796919
148Spontaneous hematomas (HP:0007420)1.67414340
149Short tibia (HP:0005736)1.66996480
150Rough bone trabeculation (HP:0100670)1.66223762
151Ectopic kidney (HP:0000086)1.65227836
152Hypoalbuminemia (HP:0003073)1.64919643
153Abnormal albumin level (HP:0012116)1.64919643
154Postaxial foot polydactyly (HP:0001830)1.64420116
155Thyroid carcinoma (HP:0002890)1.64194250
156Hepatocellular necrosis (HP:0001404)1.63897517
157Acute myeloid leukemia (HP:0004808)1.63442881
158Abnormality of the pons (HP:0007361)1.62939786
159Symptomatic seizures (HP:0011145)1.62653053
160Abnormal hair whorl (HP:0010721)1.62021091
161Neoplasm of the tracheobronchial system (HP:0100552)1.62008697
162Abnormality of midbrain morphology (HP:0002418)1.61692979
163Molar tooth sign on MRI (HP:0002419)1.61692979
164Sloping forehead (HP:0000340)1.60981872
165Abnormality of the fovea (HP:0000493)1.60713271
166Facial cleft (HP:0002006)1.59034683
167Patellar aplasia (HP:0006443)1.57914852
168Prostate neoplasm (HP:0100787)1.57142089
169Duodenal stenosis (HP:0100867)1.56911648
170Small intestinal stenosis (HP:0012848)1.56911648
171Impulsivity (HP:0100710)1.56842258
172Short middle phalanx of the 5th finger (HP:0004220)1.56810263
173Preaxial hand polydactyly (HP:0001177)1.55458586
174Hypoplasia of the thymus (HP:0000778)1.54520798
175Oligohydramnios (HP:0001562)1.53855101
176Degeneration of anterior horn cells (HP:0002398)1.53829067
177Abnormality of the anterior horn cell (HP:0006802)1.53829067
178Reduced antithrombin III activity (HP:0001976)1.53675120
179Deep philtrum (HP:0002002)1.52759370
180Cellular immunodeficiency (HP:0005374)1.51959801
181Severe visual impairment (HP:0001141)1.51358504
182Chronic bronchitis (HP:0004469)1.50270497

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TAOK33.27484211
2ZAK2.99023633
3STK162.72580828
4VRK12.65763063
5PASK2.46038086
6NUAK12.44669415
7ERBB32.38684283
8SRPK12.35752207
9GRK12.32866606
10MST42.18481736
11TEC2.06033485
12MAP4K22.00654499
13TRIM281.97738181
14MAPK131.92729625
15AKT31.85354827
16BRSK21.83223144
17IRAK41.72329335
18PLK41.67069874
19MAP3K141.66123792
20PLK31.61220743
21MKNK11.60520713
22TRPM71.51248148
23DYRK31.48061180
24INSRR1.47217823
25CDC71.44254352
26STK391.41665874
27NLK1.41145280
28ATR1.40563723
29FRK1.40514447
30WNK31.40205618
31WNK41.39942463
32PAK31.38745329
33EIF2AK21.38325195
34OXSR11.35642350
35YES11.33807461
36CASK1.33428294
37TXK1.32660187
38BMPR21.32636474
39STK38L1.31951686
40STK241.28341315
41BUB11.22603832
42PLK11.19794895
43STK41.19676946
44CLK11.19522269
45IRAK31.19041668
46CAMKK21.18621628
47IKBKB1.18566417
48OBSCN1.18504993
49CDK81.15929886
50PRKCQ1.15271657
51MAP3K41.14579866
52EIF2AK31.13369045
53IKBKE1.11629940
54AURKB1.10806105
55MKNK21.09329206
56TGFBR11.09238974
57BRSK11.08953487
58EPHA31.07132558
59RPS6KB21.04387878
60MAPK151.04332330
61PRKCE1.04314180
62DAPK21.03846369
63BMPR1B1.03239387
64BTK1.03131608
65PIM11.02424951
66JAK31.02229613
67WEE11.01346804
68CDK71.01062151
69CHUK1.01018276
70GRK70.99678891
71RPS6KA40.99582990
72SGK20.99427813
73PTK2B0.94939109
74MUSK0.94066624
75SIK30.93723736
76NEK20.90622567
77TLK10.87183007
78CHEK20.86442408
79ATM0.86397523
80PRKCG0.85218892
81RPS6KA60.85144336
82DYRK20.83723564
83PRKCI0.82006376
84HIPK20.81089284
85RPS6KL10.80768798
86RPS6KC10.80768798
87RPS6KB10.79401510
88FLT30.78377112
89TYK20.77257426
90CCNB10.75566643
91TTK0.74942452
92MYLK0.73792122
93ADRBK20.72899662
94ADRBK10.72448046
95TNIK0.72167832
96NME20.72038618
97RPS6KA50.71998538
98NEK90.71752377
99CSNK1G20.71347864
100BCR0.70447081
101PLK20.70349476
102MELK0.70110060
103SYK0.69325075
104PRKG20.68213541
105PRPF4B0.67825031
106PIM20.65635105
107CSNK2A10.65306049
108TBK10.65046046
109PIK3CG0.64722291
110EIF2AK10.64086947
111ACVR1B0.64054610
112LATS10.63931080
113TNK20.63323138
114KIT0.62730300
115CSNK1A1L0.61878452
116ITK0.61864294
117IRAK10.61362996
118CSNK1G30.61022707
119LYN0.60782880
120STK100.59593652
121CHEK10.58367314
122PINK10.57908253
123MAP4K10.56557837
124MAP3K120.56338380
125CSNK1G10.56230775
126TSSK60.56139428
127BRD40.55883939
128CDK30.55354281
129AURKA0.55309929
130GRK50.53504282
131PIK3CA0.52452550
132MARK30.51613963
133CSF1R0.50866788
134MAPK30.50206723
135FES0.49647671
136NTRK30.49060878
137STK30.46081709
138GRK60.44306382
139MAP2K70.43997844
140FGFR20.43639633
141MAP2K60.43323584
142PRKCZ0.43023443
143PHKG10.42829955
144PHKG20.42829955
145VRK20.42176410
146TIE10.39223943
147MARK10.39072377
148STK110.37316265
149PKN10.36055995
150LCK0.35245092
151PRKACA0.34405277
152BLK0.33753262
153CSNK1A10.33306517
154FER0.33240277

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.41951213
2Mismatch repair_Homo sapiens_hsa034303.35987775
3Non-homologous end-joining_Homo sapiens_hsa034503.24144671
4Protein export_Homo sapiens_hsa030603.16377823
5Fanconi anemia pathway_Homo sapiens_hsa034602.83381006
6Base excision repair_Homo sapiens_hsa034102.77935481
7Homologous recombination_Homo sapiens_hsa034402.76402220
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.56607438
9Nucleotide excision repair_Homo sapiens_hsa034202.53870338
10Spliceosome_Homo sapiens_hsa030402.45900626
11Caffeine metabolism_Homo sapiens_hsa002322.43396621
12Basal transcription factors_Homo sapiens_hsa030222.39927717
13Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.38309887
14Cell cycle_Homo sapiens_hsa041102.37371328
15RNA polymerase_Homo sapiens_hsa030202.34536463
16Butanoate metabolism_Homo sapiens_hsa006502.29983985
17Tryptophan metabolism_Homo sapiens_hsa003802.29820683
18Ribosome_Homo sapiens_hsa030102.25273098
19Nitrogen metabolism_Homo sapiens_hsa009102.24542665
20Proteasome_Homo sapiens_hsa030502.20444516
21RNA degradation_Homo sapiens_hsa030182.18951768
22alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.14302868
23Maturity onset diabetes of the young_Homo sapiens_hsa049502.11097008
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.06993935
25Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.05780582
26Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.91053621
27Pyrimidine metabolism_Homo sapiens_hsa002401.88008409
28RNA transport_Homo sapiens_hsa030131.85054266
29Primary immunodeficiency_Homo sapiens_hsa053401.71024648
30Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.62558447
31Ether lipid metabolism_Homo sapiens_hsa005651.62362199
32Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.62241136
33One carbon pool by folate_Homo sapiens_hsa006701.57046478
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.53494122
35Propanoate metabolism_Homo sapiens_hsa006401.45456686
36Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.41921772
37Nicotine addiction_Homo sapiens_hsa050331.41730000
38Olfactory transduction_Homo sapiens_hsa047401.37352174
39Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.36595048
40Purine metabolism_Homo sapiens_hsa002301.27972683
41ABC transporters_Homo sapiens_hsa020101.23926051
42Taste transduction_Homo sapiens_hsa047421.22527600
43p53 signaling pathway_Homo sapiens_hsa041151.20078760
44Primary bile acid biosynthesis_Homo sapiens_hsa001201.19928008
45NF-kappa B signaling pathway_Homo sapiens_hsa040641.19435662
46Steroid hormone biosynthesis_Homo sapiens_hsa001401.19005496
47mRNA surveillance pathway_Homo sapiens_hsa030151.18720538
48N-Glycan biosynthesis_Homo sapiens_hsa005101.18026761
49SNARE interactions in vesicular transport_Homo sapiens_hsa041301.17750641
50Transcriptional misregulation in cancer_Homo sapiens_hsa052021.16192189
51Herpes simplex infection_Homo sapiens_hsa051681.09283217
52Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.04951218
53Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.04491740
54Selenocompound metabolism_Homo sapiens_hsa004501.04468894
55Chemical carcinogenesis_Homo sapiens_hsa052041.04167972
56Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.02903419
57Retinol metabolism_Homo sapiens_hsa008301.01950854
58Graft-versus-host disease_Homo sapiens_hsa053321.01248651
59beta-Alanine metabolism_Homo sapiens_hsa004100.97562616
60Systemic lupus erythematosus_Homo sapiens_hsa053220.97414863
61Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.93405552
62Epstein-Barr virus infection_Homo sapiens_hsa051690.92815959
63Dorso-ventral axis formation_Homo sapiens_hsa043200.91313550
64Antigen processing and presentation_Homo sapiens_hsa046120.90807085
65Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.89174316
66Arachidonic acid metabolism_Homo sapiens_hsa005900.88867765
67Intestinal immune network for IgA production_Homo sapiens_hsa046720.88710248
68Morphine addiction_Homo sapiens_hsa050320.88197773
69Hematopoietic cell lineage_Homo sapiens_hsa046400.87672778
70Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.86556196
71Glycerolipid metabolism_Homo sapiens_hsa005610.85279171
72Measles_Homo sapiens_hsa051620.84943353
73Viral carcinogenesis_Homo sapiens_hsa052030.83111629
74Legionellosis_Homo sapiens_hsa051340.82060014
75Sulfur metabolism_Homo sapiens_hsa009200.81239884
76Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.79593927
77Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.75761669
78Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.75216972
79Thyroid cancer_Homo sapiens_hsa052160.75049396
80Insulin secretion_Homo sapiens_hsa049110.74387467
81HTLV-I infection_Homo sapiens_hsa051660.74216175
82Fat digestion and absorption_Homo sapiens_hsa049750.71672883
83Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.71101285
84Fatty acid degradation_Homo sapiens_hsa000710.69666187
85RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.69098613
86Serotonergic synapse_Homo sapiens_hsa047260.68772618
87Circadian entrainment_Homo sapiens_hsa047130.68245613
88Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.66504941
89Drug metabolism - other enzymes_Homo sapiens_hsa009830.64609933
90Folate biosynthesis_Homo sapiens_hsa007900.64275455
91Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.63284524
92Lysine degradation_Homo sapiens_hsa003100.62928541
93Collecting duct acid secretion_Homo sapiens_hsa049660.61265658
94Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.60664913
95Galactose metabolism_Homo sapiens_hsa000520.59911510
96Allograft rejection_Homo sapiens_hsa053300.59086250
97Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.57215797
98Calcium signaling pathway_Homo sapiens_hsa040200.56510091
99Asthma_Homo sapiens_hsa053100.55744868
100Other glycan degradation_Homo sapiens_hsa005110.54863192
101Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.54293093
102Apoptosis_Homo sapiens_hsa042100.54150005
103GABAergic synapse_Homo sapiens_hsa047270.53496746
104Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.52180240
105Hepatitis B_Homo sapiens_hsa051610.51877103
106Glutamatergic synapse_Homo sapiens_hsa047240.51657626
107Salivary secretion_Homo sapiens_hsa049700.51644631
108TGF-beta signaling pathway_Homo sapiens_hsa043500.51145840
109Leishmaniasis_Homo sapiens_hsa051400.51081140
110Alzheimers disease_Homo sapiens_hsa050100.50764503
111Ovarian steroidogenesis_Homo sapiens_hsa049130.50575266
112Jak-STAT signaling pathway_Homo sapiens_hsa046300.50219693
113Prostate cancer_Homo sapiens_hsa052150.49852273
114Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.49603459
115Fatty acid metabolism_Homo sapiens_hsa012120.46753209
116Alcoholism_Homo sapiens_hsa050340.46314096
117Pentose and glucuronate interconversions_Homo sapiens_hsa000400.45592740
118Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.45500383
119Notch signaling pathway_Homo sapiens_hsa043300.45474339
120Huntingtons disease_Homo sapiens_hsa050160.45376891
121Regulation of autophagy_Homo sapiens_hsa041400.45237124
122T cell receptor signaling pathway_Homo sapiens_hsa046600.43937796
123Glycerophospholipid metabolism_Homo sapiens_hsa005640.43500646
124Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.42611362
125Peroxisome_Homo sapiens_hsa041460.42032589
126Cardiac muscle contraction_Homo sapiens_hsa042600.41950027
127NOD-like receptor signaling pathway_Homo sapiens_hsa046210.41427479
128Phototransduction_Homo sapiens_hsa047440.40110650
129Influenza A_Homo sapiens_hsa051640.39534867
130Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38816470
131Steroid biosynthesis_Homo sapiens_hsa001000.38246050
132Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.38121374
133Small cell lung cancer_Homo sapiens_hsa052220.37652031
134Long-term depression_Homo sapiens_hsa047300.37646791
135Colorectal cancer_Homo sapiens_hsa052100.37432065
136Glycosaminoglycan degradation_Homo sapiens_hsa005310.35249020
137Parkinsons disease_Homo sapiens_hsa050120.34678832
138Circadian rhythm_Homo sapiens_hsa047100.34294269
139Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.34167096
140MicroRNAs in cancer_Homo sapiens_hsa052060.33143248
141Linoleic acid metabolism_Homo sapiens_hsa005910.32458724
142Pathways in cancer_Homo sapiens_hsa052000.31364386
143B cell receptor signaling pathway_Homo sapiens_hsa046620.31103271
144Pertussis_Homo sapiens_hsa051330.30480322
145Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.28722419
146Autoimmune thyroid disease_Homo sapiens_hsa053200.28310870
147Endometrial cancer_Homo sapiens_hsa052130.27414200
148Type I diabetes mellitus_Homo sapiens_hsa049400.26602454
149Metabolic pathways_Homo sapiens_hsa011000.26207316
150PI3K-Akt signaling pathway_Homo sapiens_hsa041510.25057534
151Sphingolipid metabolism_Homo sapiens_hsa006000.22743181
152FoxO signaling pathway_Homo sapiens_hsa040680.22363945
153Toxoplasmosis_Homo sapiens_hsa051450.18769316
154Acute myeloid leukemia_Homo sapiens_hsa052210.18761419
155Hippo signaling pathway_Homo sapiens_hsa043900.17963552
156Oxidative phosphorylation_Homo sapiens_hsa001900.17957945
157Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.17881077

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