TCEB1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proteasome assembly (GO:0043248)5.66993516
2transcription elongation from RNA polymerase III promoter (GO:0006385)5.37814917
3termination of RNA polymerase III transcription (GO:0006386)5.37814917
4respiratory electron transport chain (GO:0022904)5.31156284
5electron transport chain (GO:0022900)5.22283791
67-methylguanosine mRNA capping (GO:0006370)5.08113361
77-methylguanosine RNA capping (GO:0009452)4.95877135
8RNA capping (GO:0036260)4.95877135
9ribosome assembly (GO:0042255)4.75752755
10establishment of protein localization to mitochondrial membrane (GO:0090151)4.74317120
11rRNA modification (GO:0000154)4.71983905
12protein complex biogenesis (GO:0070271)4.65287989
13purine nucleobase biosynthetic process (GO:0009113)4.60900383
14transcription elongation from RNA polymerase I promoter (GO:0006362)4.56582870
15mitochondrial respiratory chain complex assembly (GO:0033108)4.54707952
16translational termination (GO:0006415)4.54480658
17positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.52219437
18negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.50904724
19viral transcription (GO:0019083)4.48231632
20protein neddylation (GO:0045116)4.48097470
21anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:04.45165793
22mitochondrial respiratory chain complex I assembly (GO:0032981)4.44302519
23NADH dehydrogenase complex assembly (GO:0010257)4.44302519
24mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.44302519
25chaperone-mediated protein transport (GO:0072321)4.40888756
26regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.40157965
27termination of RNA polymerase I transcription (GO:0006363)4.36329537
28transcription from RNA polymerase I promoter (GO:0006360)4.25444816
29SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.23871314
30cotranslational protein targeting to membrane (GO:0006613)4.22877738
31protein targeting to ER (GO:0045047)4.16516103
32respiratory chain complex IV assembly (GO:0008535)4.09089186
33regulation of cellular amino acid metabolic process (GO:0006521)4.08679041
34mitotic metaphase plate congression (GO:0007080)4.08128365
35negative regulation of ligase activity (GO:0051352)4.07528651
36negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.07528651
37positive regulation of ubiquitin-protein transferase activity (GO:0051443)4.06752559
38amino acid salvage (GO:0043102)4.01397969
39L-methionine salvage (GO:0071267)4.01397969
40L-methionine biosynthetic process (GO:0071265)4.01397969
41establishment of protein localization to endoplasmic reticulum (GO:0072599)4.00900349
42mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.00039685
43ribosome biogenesis (GO:0042254)3.99356038
44protein localization to endoplasmic reticulum (GO:0070972)3.94113168
45nucleobase biosynthetic process (GO:0046112)3.91493079
46translation (GO:0006412)3.86928035
47L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.86598325
48positive regulation of ligase activity (GO:0051351)3.85749650
49transcription initiation from RNA polymerase I promoter (GO:0006361)3.83359061
50cytochrome complex assembly (GO:0017004)3.80917877
51cullin deneddylation (GO:0010388)3.80228081
52ribosomal small subunit assembly (GO:0000028)3.80026114
53exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.78577464
54regulation of mitochondrial translation (GO:0070129)3.77778914
55translational elongation (GO:0006414)3.75796020
56water-soluble vitamin biosynthetic process (GO:0042364)3.74843208
57nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.73441259
58protein deneddylation (GO:0000338)3.72692815
59protein targeting to mitochondrion (GO:0006626)3.66395340
60establishment of protein localization to mitochondrion (GO:0072655)3.65577405
61DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.64802075
62signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.62120256
63signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.62120256
64signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.62120256
65maturation of SSU-rRNA (GO:0030490)3.60811364
66maturation of 5.8S rRNA (GO:0000460)3.60487472
67guanosine-containing compound biosynthetic process (GO:1901070)3.59115535
68signal transduction involved in DNA damage checkpoint (GO:0072422)3.58560151
69signal transduction involved in DNA integrity checkpoint (GO:0072401)3.58560151
70rRNA methylation (GO:0031167)3.58286418
71translational initiation (GO:0006413)3.57560953
72intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.56544887
73signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.56544887
74ribonucleoprotein complex biogenesis (GO:0022613)3.56469534
75hydrogen ion transmembrane transport (GO:1902600)3.55793436
76signal transduction involved in cell cycle checkpoint (GO:0072395)3.54489370
77regulation of ubiquitin-protein transferase activity (GO:0051438)3.53767076
78ATP synthesis coupled proton transport (GO:0015986)3.53761935
79energy coupled proton transport, down electrochemical gradient (GO:0015985)3.53761935
80blastocyst development (GO:0001824)3.52410437
81protein localization to mitochondrion (GO:0070585)3.51894136
82DNA deamination (GO:0045006)3.50217984
83ATP biosynthetic process (GO:0006754)3.46490222
84cellular protein complex disassembly (GO:0043624)3.46410864
85rRNA processing (GO:0006364)3.45165814
86spliceosomal snRNP assembly (GO:0000387)3.44614699
87viral life cycle (GO:0019058)3.42438140
88regulation of ligase activity (GO:0051340)3.38433733
89signal peptide processing (GO:0006465)3.37822481
90DNA replication checkpoint (GO:0000076)3.34175607
91* DNA-templated transcription, elongation (GO:0006354)3.32886063
92* transcription elongation from RNA polymerase II promoter (GO:0006368)3.32837425
93rRNA metabolic process (GO:0016072)3.32725686
94purine nucleoside triphosphate biosynthetic process (GO:0009145)3.32460343
95ribosomal large subunit biogenesis (GO:0042273)3.31913349
96mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.31475741
97nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.26240990
98purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.25783247
99cellular component biogenesis (GO:0044085)3.24068090
100transcription-coupled nucleotide-excision repair (GO:0006283)3.18826817
101proton transport (GO:0015992)3.18442809
102peptidyl-histidine modification (GO:0018202)3.12376970
103DNA damage response, detection of DNA damage (GO:0042769)3.12095238
104antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.11749758
105regulation of cellular amine metabolic process (GO:0033238)3.10983749
106hydrogen transport (GO:0006818)3.10430432
107microtubule depolymerization (GO:0007019)3.09992392
108GTP biosynthetic process (GO:0006183)3.08954165
109intracellular protein transmembrane import (GO:0044743)3.08917963
110formation of translation preinitiation complex (GO:0001731)3.08739298
111regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.08031909
112transcription from mitochondrial promoter (GO:0006390)3.07262811
113CENP-A containing nucleosome assembly (GO:0034080)3.07047814
114tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.05919851
115RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.05919851
116protein-cofactor linkage (GO:0018065)3.05171100
117G1/S transition of mitotic cell cycle (GO:0000082)3.02679824
118cell cycle G1/S phase transition (GO:0044843)3.02679824
119DNA double-strand break processing (GO:0000729)3.02284407
120metaphase plate congression (GO:0051310)3.01809618
121spliceosomal complex assembly (GO:0000245)2.99470758
122GMP metabolic process (GO:0046037)2.99011896
123tRNA processing (GO:0008033)2.98473799
124mitochondrial transport (GO:0006839)2.97378437
125organelle disassembly (GO:1903008)2.96368587
126pseudouridine synthesis (GO:0001522)2.94671752
127methionine biosynthetic process (GO:0009086)2.93919569
128* positive regulation of viral transcription (GO:0050434)2.93872405
129folic acid transport (GO:0015884)2.93184494
130positive regulation of mitochondrial fission (GO:0090141)2.92607550
131histone exchange (GO:0043486)2.91214356
132ribonucleoside triphosphate biosynthetic process (GO:0009201)2.90574635
133ribosomal small subunit biogenesis (GO:0042274)2.89673759
134histone mRNA metabolic process (GO:0008334)2.85638054
135kinetochore assembly (GO:0051382)2.85471390
136protein K6-linked ubiquitination (GO:0085020)2.85443992
137transcription from RNA polymerase III promoter (GO:0006383)2.84783046
138regulation of mitotic spindle checkpoint (GO:1903504)2.84782876
139regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.84782876
140antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.84029518
141positive regulation of cell cycle arrest (GO:0071158)2.82901576
142negative regulation of protein ubiquitination (GO:0031397)2.81577912
143regulation of spindle organization (GO:0090224)2.81459910
144chromatin remodeling at centromere (GO:0031055)2.80168907
145lung-associated mesenchyme development (GO:0060484)2.80157496
146DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.79222416
147keratinocyte development (GO:0003334)2.79102100
148protein complex disassembly (GO:0043241)2.77157749
149ncRNA processing (GO:0034470)2.76451410
150recombinational repair (GO:0000725)2.75758288
151replication fork processing (GO:0031297)2.75373202
152kynurenine metabolic process (GO:0070189)2.75139747

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse6.05446571
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.96059646
3* GABP_17652178_ChIP-ChIP_JURKAT_Human4.32084955
4JARID1A_20064375_ChIP-Seq_MESCs_Mouse4.21099426
5EST1_17652178_ChIP-ChIP_JURKAT_Human4.11589021
6* ETS1_20019798_ChIP-Seq_JURKAT_Human3.92446144
7CREB1_15753290_ChIP-ChIP_HEK293T_Human3.90284155
8CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.54563202
9MYC_18555785_ChIP-Seq_MESCs_Mouse3.53229961
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.35900952
11HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.07521109
12CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.81157301
13SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.74693746
14MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.71275032
15VDR_23849224_ChIP-Seq_CD4+_Human2.65723131
16MYC_18358816_ChIP-ChIP_MESCs_Mouse2.64175499
17MYC_19079543_ChIP-ChIP_MESCs_Mouse2.64144171
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.50228751
19* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.45722750
20EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.26991810
21FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.26756937
22ZNF274_21170338_ChIP-Seq_K562_Hela2.17931822
23* E2F4_17652178_ChIP-ChIP_JURKAT_Human2.13832015
24THAP11_20581084_ChIP-Seq_MESCs_Mouse2.12599451
25DCP1A_22483619_ChIP-Seq_HELA_Human2.09017103
26E2F7_22180533_ChIP-Seq_HELA_Human2.08428935
27YY1_21170310_ChIP-Seq_MESCs_Mouse2.08181608
28ELK1_19687146_ChIP-ChIP_HELA_Human2.02964428
29* PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.01002254
30XRN2_22483619_ChIP-Seq_HELA_Human1.98983767
31E2F1_18555785_ChIP-Seq_MESCs_Mouse1.95945373
32SRF_21415370_ChIP-Seq_HL-1_Mouse1.94749311
33MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.94438159
34* GABP_19822575_ChIP-Seq_HepG2_Human1.90306219
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.88641144
36FOXP3_21729870_ChIP-Seq_TREG_Human1.86806073
37* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.85029854
38* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.82632473
39TTF2_22483619_ChIP-Seq_HELA_Human1.73636535
40NANOG_18555785_ChIP-Seq_MESCs_Mouse1.72089071
41ELK1_22589737_ChIP-Seq_MCF10A_Human1.71048304
42* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.71015523
43YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.64916676
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60851771
45ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.58818912
46FOXM1_23109430_ChIP-Seq_U2OS_Human1.58177040
47MYCN_18555785_ChIP-Seq_MESCs_Mouse1.54740141
48MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.47425357
49AR_21909140_ChIP-Seq_LNCAP_Human1.42860264
50ELF1_17652178_ChIP-ChIP_JURKAT_Human1.41851177
51POU3F2_20337985_ChIP-ChIP_501MEL_Human1.41117072
52GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35121570
53KAP1_22055183_ChIP-Seq_ESCs_Mouse1.34284780
54* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.30966776
55P300_19829295_ChIP-Seq_ESCs_Human1.27600159
56IGF1R_20145208_ChIP-Seq_DFB_Human1.25968662
57* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.25930855
58POU5F1_16153702_ChIP-ChIP_HESCs_Human1.25467623
59TP53_22573176_ChIP-Seq_HFKS_Human1.24839587
60POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.22798401
61CTBP1_25329375_ChIP-Seq_LNCAP_Human1.21668460
62MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.21201317
63* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.21081422
64TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19564490
65CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.19310320
66HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.13855308
67* FLI1_27457419_Chip-Seq_LIVER_Mouse1.13198353
68KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.12537322
69SALL1_21062744_ChIP-ChIP_HESCs_Human1.12252130
70GBX2_23144817_ChIP-Seq_PC3_Human1.11732446
71HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.10278564
72RBPJ_22232070_ChIP-Seq_NCS_Mouse1.09352043
73KDM5A_27292631_Chip-Seq_BREAST_Human1.09172767
74* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.07970781
75ER_23166858_ChIP-Seq_MCF-7_Human1.07313907
76RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06684362
77MYC_18940864_ChIP-ChIP_HL60_Human1.06200205
78SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.04893253
79VDR_22108803_ChIP-Seq_LS180_Human1.03518004
80CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.01062493
81ZFP57_27257070_Chip-Seq_ESCs_Mouse1.00084452
82* PCGF2_27294783_Chip-Seq_ESCs_Mouse0.97244992
83NANOG_19829295_ChIP-Seq_ESCs_Human0.96872454
84SOX2_19829295_ChIP-Seq_ESCs_Human0.96872454
85BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.93227213
86* NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.91217213
87CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.90811688
88UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.90589347
89AR_20517297_ChIP-Seq_VCAP_Human0.90444126
90GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.89303810
91SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.87664987
92IRF1_19129219_ChIP-ChIP_H3396_Human0.86366682
93FOXA1_27270436_Chip-Seq_PROSTATE_Human0.85801971
94FOXA1_25329375_ChIP-Seq_VCAP_Human0.85801971
95* SOX17_20123909_ChIP-Seq_XEN_Mouse0.85233052
96NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.85179242
97KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.85061529
98CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.84676940
99* CBP_20019798_ChIP-Seq_JUKART_Human0.84402744
100* IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.84402744
101ELF5_23300383_ChIP-Seq_T47D_Human0.83785021
102FUS_26573619_Chip-Seq_HEK293_Human0.82421849
103TAF15_26573619_Chip-Seq_HEK293_Human0.81957234
104NCOR_22424771_ChIP-Seq_293T_Human0.81139021
105ZFX_18555785_ChIP-Seq_MESCs_Mouse0.80992052
106* SUZ12_27294783_Chip-Seq_NPCs_Mouse0.77857330
107* NFE2_27457419_Chip-Seq_LIVER_Mouse0.77152232
108NOTCH1_21737748_ChIP-Seq_TLL_Human0.77134067
109* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.76525538
110FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.76440993
111* EZH2_27294783_Chip-Seq_NPCs_Mouse0.76117534
112* NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.75046102
113POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.70069597
114E2F1_21310950_ChIP-Seq_MCF-7_Human0.69832995
115EWS_26573619_Chip-Seq_HEK293_Human0.69780838
116CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.69407787
117KLF4_18555785_ChIP-Seq_MESCs_Mouse0.68935030
118* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.68781417
119* TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.68477445
120SOX2_16153702_ChIP-ChIP_HESCs_Human0.68044918
121SOX2_18555785_ChIP-Seq_MESCs_Mouse0.67002685
122CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.66966499
123NANOG_16153702_ChIP-ChIP_HESCs_Human0.66533580
124ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.66053977
125ZNF263_19887448_ChIP-Seq_K562_Human0.65632884
126* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.65397869
127CTBP2_25329375_ChIP-Seq_LNCAP_Human0.65294849
128NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.65152098
129FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.62066076
130E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.61616517

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.51763830
2MP0003718_maternal_effect4.31612491
3MP0003806_abnormal_nucleotide_metabolis3.88795518
4MP0008260_abnormal_autophagy3.60730541
5MP0003880_abnormal_central_pattern3.26354776
6MP0004957_abnormal_blastocyst_morpholog3.12819552
7MP0003111_abnormal_nucleus_morphology2.93752730
8MP0001529_abnormal_vocalization2.68505232
9MP0002938_white_spotting2.53184205
10MP0002837_dystrophic_cardiac_calcinosis2.44478498
11MP0003186_abnormal_redox_activity2.42801881
12MP0010094_abnormal_chromosome_stability2.40326146
13MP0008877_abnormal_DNA_methylation2.35151295
14MP0001905_abnormal_dopamine_level2.32759453
15MP0003077_abnormal_cell_cycle2.27683523
16MP0008058_abnormal_DNA_repair2.24003348
17MP0008932_abnormal_embryonic_tissue2.22837291
18MP0003786_premature_aging2.19767676
19MP0003136_yellow_coat_color2.15235525
20MP0003195_calcinosis2.15078179
21MP0003123_paternal_imprinting2.05864366
22MP0008057_abnormal_DNA_replication2.02355651
23MP0006072_abnormal_retinal_apoptosis2.00990130
24MP0009046_muscle_twitch2.00883449
25MP0003315_abnormal_perineum_morphology1.93841376
26MP0000569_abnormal_digit_pigmentation1.81164528
27MP0001440_abnormal_grooming_behavior1.78699833
28MP0001188_hyperpigmentation1.73721891
29MP0001542_abnormal_bone_strength1.71163847
30MP0002734_abnormal_mechanical_nocicepti1.68432194
31MP0002163_abnormal_gland_morphology1.64995504
32MP0006292_abnormal_olfactory_placode1.61468152
33MP0002102_abnormal_ear_morphology1.60245746
34MP0004270_analgesia1.59769712
35MP0005551_abnormal_eye_electrophysiolog1.55432670
36MP0001968_abnormal_touch/_nociception1.54300450
37MP0006035_abnormal_mitochondrial_morpho1.49545261
38MP0004859_abnormal_synaptic_plasticity1.47016627
39MP0003950_abnormal_plasma_membrane1.46448125
40MP0002736_abnormal_nociception_after1.46072957
41MP0006276_abnormal_autonomic_nervous1.45989862
42MP0001764_abnormal_homeostasis1.44101645
43MP0003646_muscle_fatigue1.43924967
44MP0005395_other_phenotype1.42275973
45MP0005084_abnormal_gallbladder_morpholo1.40330421
46MP0005253_abnormal_eye_physiology1.40054515
47MP0002272_abnormal_nervous_system1.37966922
48MP0008875_abnormal_xenobiotic_pharmacok1.35877433
49MP0003938_abnormal_ear_development1.34928420
50MP0004145_abnormal_muscle_electrophysio1.32810523
51MP0003635_abnormal_synaptic_transmissio1.32590982
52MP0002064_seizures1.32549715
53MP0002210_abnormal_sex_determination1.30912999
54MP0002735_abnormal_chemical_nociception1.26173139
55MP0001984_abnormal_olfaction1.24911570
56MP0009745_abnormal_behavioral_response1.24210752
57MP0009379_abnormal_foot_pigmentation1.24120801
58MP0001986_abnormal_taste_sensitivity1.22534231
59MP0001661_extended_life_span1.22394406
60MP0003011_delayed_dark_adaptation1.22097923
61MP0001929_abnormal_gametogenesis1.22068845
62MP0005646_abnormal_pituitary_gland1.21990699
63MP0008872_abnormal_physiological_respon1.20076826
64MP0001970_abnormal_pain_threshold1.19017730
65MP0008007_abnormal_cellular_replicative1.18824206
66MP0006036_abnormal_mitochondrial_physio1.18817885
67MP0001730_embryonic_growth_arrest1.18527013
68MP0000631_abnormal_neuroendocrine_gland1.17903194
69MP0001485_abnormal_pinna_reflex1.16579885
70MP0002277_abnormal_respiratory_mucosa1.16553534
71MP0002572_abnormal_emotion/affect_behav1.16218865
72MP0001293_anophthalmia1.13578634
73MP0002234_abnormal_pharynx_morphology1.13378644
74MP0005423_abnormal_somatic_nervous1.12939325
75MP0005266_abnormal_metabolism1.12696653
76MP0003879_abnormal_hair_cell1.11503363
77MP0002095_abnormal_skin_pigmentation1.11204955
78MP0005408_hypopigmentation1.10654486
79MP0002160_abnormal_reproductive_system1.09968549
80MP0003941_abnormal_skin_development1.09401540
81MP0002090_abnormal_vision1.09218785
82MP0004142_abnormal_muscle_tone1.09008303
83MP0001501_abnormal_sleep_pattern1.08907109
84MP0002063_abnormal_learning/memory/cond1.08390021
85MP0001145_abnormal_male_reproductive1.05607239
86MP0005389_reproductive_system_phenotype1.05468656
87MP0001486_abnormal_startle_reflex1.05264107
88MP0002067_abnormal_sensory_capabilities1.04502153
89MP0000372_irregular_coat_pigmentation1.03026108
90MP0000653_abnormal_sex_gland1.02941937
91MP0000750_abnormal_muscle_regeneration1.01382418
92MP0002638_abnormal_pupillary_reflex1.00913059
93MP0000427_abnormal_hair_cycle0.99548187
94MP0001727_abnormal_embryo_implantation0.99321581
95MP0003698_abnormal_male_reproductive0.99189396
96MP0002184_abnormal_innervation0.99060865
97MP0002733_abnormal_thermal_nociception0.97612868
98MP0005451_abnormal_body_composition0.95887840
99MP0005171_absent_coat_pigmentation0.93277041
100MP0003137_abnormal_impulse_conducting0.92708159
101MP0002876_abnormal_thyroid_physiology0.92641047
102MP0004147_increased_porphyrin_level0.92391236
103MP0004924_abnormal_behavior0.90927791
104MP0005386_behavior/neurological_phenoty0.90927791
105MP0005410_abnormal_fertilization0.90764821
106MP0000647_abnormal_sebaceous_gland0.89317354
107MP0005645_abnormal_hypothalamus_physiol0.88526035
108MP0003890_abnormal_embryonic-extraembry0.87009735
109MP0005332_abnormal_amino_acid0.85954882
110MP0000350_abnormal_cell_proliferation0.85394608
111MP0002653_abnormal_ependyma_morphology0.84460237
112MP0003221_abnormal_cardiomyocyte_apopto0.82590746
113MP0004133_heterotaxia0.82430306
114MP0003878_abnormal_ear_physiology0.81807564
115MP0005377_hearing/vestibular/ear_phenot0.81807564
116MP0000049_abnormal_middle_ear0.81534248
117MP0005379_endocrine/exocrine_gland_phen0.81220871
118MP0000778_abnormal_nervous_system0.80552791
119MP0010030_abnormal_orbit_morphology0.80481693
120MP0005195_abnormal_posterior_eye0.80435164
121MP0003937_abnormal_limbs/digits/tail_de0.79528192
122MP0001919_abnormal_reproductive_system0.79200260
123MP0009697_abnormal_copulation0.79105970
124MP0003329_amyloid_beta_deposits0.78525831
125MP0009333_abnormal_splenocyte_physiolog0.77717216
126MP0002161_abnormal_fertility/fecundity0.77326805
127MP0010386_abnormal_urinary_bladder0.77250911
128MP0005174_abnormal_tail_pigmentation0.77129451
129MP0000358_abnormal_cell_content/0.76135359
130MP0002751_abnormal_autonomic_nervous0.75564459
131MP0004043_abnormal_pH_regulation0.75473962
132MP0004215_abnormal_myocardial_fiber0.75367585
133MP0002066_abnormal_motor_capabilities/c0.73094680
134MP0004381_abnormal_hair_follicle0.72674519
135MP0001963_abnormal_hearing_physiology0.72472417
136MP0005499_abnormal_olfactory_system0.69506573
137MP0005394_taste/olfaction_phenotype0.69506573
138MP0008789_abnormal_olfactory_epithelium0.69378956
139MP0004084_abnormal_cardiac_muscle0.68578826
140MP0002752_abnormal_somatic_nervous0.68088198
141MP0004742_abnormal_vestibular_system0.67111850

Predicted human phenotypes

RankGene SetZ-score
1Cerebral hypomyelination (HP:0006808)4.69771230
2Birth length less than 3rd percentile (HP:0003561)4.56321820
3Breast hypoplasia (HP:0003187)4.22317230
4Cerebral edema (HP:0002181)3.70850895
5Acute necrotizing encephalopathy (HP:0006965)3.69205202
6Carpal bone hypoplasia (HP:0001498)3.60733422
73-Methylglutaconic aciduria (HP:0003535)3.37297575
8Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.33807272
9Mitochondrial inheritance (HP:0001427)3.29104755
10Rough bone trabeculation (HP:0100670)3.28369564
11Increased serum pyruvate (HP:0003542)3.27194548
12Abnormality of glycolysis (HP:0004366)3.27194548
13Delusions (HP:0000746)3.21367881
14Abnormal mitochondria in muscle tissue (HP:0008316)3.15629130
15Abnormality of the labia minora (HP:0012880)3.07794570
16Abnormality of alanine metabolism (HP:0010916)3.05727206
17Hyperalaninemia (HP:0003348)3.05727206
18Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.05727206
19CNS hypomyelination (HP:0003429)3.01477391
20Increased CSF lactate (HP:0002490)3.00554495
21Progressive macrocephaly (HP:0004481)3.00283797
22Molar tooth sign on MRI (HP:0002419)2.92924004
23Abnormality of midbrain morphology (HP:0002418)2.92924004
24Hepatocellular necrosis (HP:0001404)2.87453331
25Exertional dyspnea (HP:0002875)2.87301274
26Secondary amenorrhea (HP:0000869)2.86518199
27Optic disc pallor (HP:0000543)2.85452835
28Increased intramyocellular lipid droplets (HP:0012240)2.83686472
29Acute encephalopathy (HP:0006846)2.78872794
30Increased hepatocellular lipid droplets (HP:0006565)2.78861306
31Impulsivity (HP:0100710)2.73333741
32Hyperglycinemia (HP:0002154)2.72779735
33Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.71313091
34Patellar aplasia (HP:0006443)2.69246193
35True hermaphroditism (HP:0010459)2.68979031
36Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.68281329
37Methylmalonic acidemia (HP:0002912)2.65834837
38Aplasia/Hypoplasia of the patella (HP:0006498)2.64278084
39Type I transferrin isoform profile (HP:0003642)2.61632721
40Methylmalonic aciduria (HP:0012120)2.56958019
41Abnormality of the umbilical cord (HP:0010881)2.56345403
42Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.54515207
43Ureteral duplication (HP:0000073)2.54168313
44Abnormal trabecular bone morphology (HP:0100671)2.52993398
45Increased serum lactate (HP:0002151)2.49432354
46Reticulocytopenia (HP:0001896)2.48016031
47Abnormality of renal resorption (HP:0011038)2.48015848
48Premature ovarian failure (HP:0008209)2.45282204
49Pancreatic fibrosis (HP:0100732)2.44745005
50Focal motor seizures (HP:0011153)2.43615860
51Irregular epiphyses (HP:0010582)2.39012847
52Aplastic anemia (HP:0001915)2.36266965
53CNS demyelination (HP:0007305)2.35898420
54Decreased activity of mitochondrial respiratory chain (HP:0008972)2.35058959
55Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.35058959
56Aplasia/Hypoplasia involving the musculature (HP:0001460)2.34402804
57Absent radius (HP:0003974)2.33805256
58Postnatal microcephaly (HP:0005484)2.33546248
59Hypoplasia of the capital femoral epiphysis (HP:0003090)2.31329552
60Hepatic necrosis (HP:0002605)2.30955058
61Increased muscle lipid content (HP:0009058)2.28858039
62Lethargy (HP:0001254)2.27452584
63Aplasia/hypoplasia of the uterus (HP:0008684)2.24937478
64Congenital, generalized hypertrichosis (HP:0004540)2.24400203
65Absent forearm bone (HP:0003953)2.22307695
66Aplasia involving forearm bones (HP:0009822)2.22307695
67Nephronophthisis (HP:0000090)2.20539377
68Parakeratosis (HP:0001036)2.19936278
69Lipid accumulation in hepatocytes (HP:0006561)2.19796010
70Abnormality of cells of the erythroid lineage (HP:0012130)2.19722461
71Renal Fanconi syndrome (HP:0001994)2.18750740
72Unsteady gait (HP:0002317)2.18616478
73Generalized aminoaciduria (HP:0002909)2.18106864
74Congenital ichthyosiform erythroderma (HP:0007431)2.15892444
75Dysautonomia (HP:0002459)2.15755383
76Abnormality of methionine metabolism (HP:0010901)2.14739297
77Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.12930413
78Abnormal protein N-linked glycosylation (HP:0012347)2.12930413
79Abnormal protein glycosylation (HP:0012346)2.12930413
80Abnormal glycosylation (HP:0012345)2.12930413
81Abnormality of urine glucose concentration (HP:0011016)2.11882306
82Glycosuria (HP:0003076)2.11882306
83Abnormal number of erythroid precursors (HP:0012131)2.11179308
84Macrocytic anemia (HP:0001972)2.11143591
85Pallor (HP:0000980)2.08883480
86Abnormal spermatogenesis (HP:0008669)2.07512018
87Congenital stationary night blindness (HP:0007642)2.05156825
88Lactic acidosis (HP:0003128)2.04956921
89Sparse eyelashes (HP:0000653)2.04683323
90Respiratory failure (HP:0002878)2.03425788
91Respiratory difficulties (HP:0002880)2.01522373
92Type 2 muscle fiber atrophy (HP:0003554)2.00093053
93Abnormal autonomic nervous system physiology (HP:0012332)1.99168873
94Emotional lability (HP:0000712)1.98652900
95Horseshoe kidney (HP:0000085)1.98460932
96Sclerocornea (HP:0000647)1.98226622
97Areflexia of lower limbs (HP:0002522)1.98012954
98X-linked dominant inheritance (HP:0001423)1.97064583
99Brittle hair (HP:0002299)1.96144021
100Pancreatic cysts (HP:0001737)1.95736486
101Patent foramen ovale (HP:0001655)1.95122239
102Degeneration of anterior horn cells (HP:0002398)1.94762132
103Abnormality of the anterior horn cell (HP:0006802)1.94762132
104Oral leukoplakia (HP:0002745)1.94252319
105Death in infancy (HP:0001522)1.94031470
106Hypoplasia of the pons (HP:0012110)1.93843598
107Abnormalities of placenta or umbilical cord (HP:0001194)1.93554055
108Aplasia/Hypoplasia of the tibia (HP:0005772)1.93368974
109Split foot (HP:0001839)1.93297576
110Colon cancer (HP:0003003)1.91891863
111Abnormality of aspartate family amino acid metabolism (HP:0010899)1.91201534
112Abnormality of the pons (HP:0007361)1.91000526
113Adrenal hypoplasia (HP:0000835)1.89626064
114Breast aplasia (HP:0100783)1.89238612
115Exercise intolerance (HP:0003546)1.87610094
116Abnormality of the preputium (HP:0100587)1.87542803
117Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.87234388
118Absent epiphyses (HP:0010577)1.87234388
119Reduced antithrombin III activity (HP:0001976)1.86555117
120Progressive external ophthalmoplegia (HP:0000590)1.85818759
121Aplasia/Hypoplasia of the uvula (HP:0010293)1.85259656
122Shoulder girdle muscle weakness (HP:0003547)1.85071675
123Abnormality of serum amino acid levels (HP:0003112)1.83682004
124Aplasia/Hypoplasia of the breasts (HP:0010311)1.83444972
125Meckel diverticulum (HP:0002245)1.83178372
126Stenosis of the external auditory canal (HP:0000402)1.81774638
127Double outlet right ventricle (HP:0001719)1.81042999
128Congenital malformation of the right heart (HP:0011723)1.81042999
129Aplasia/Hypoplasia of the earlobes (HP:0009906)1.80708317
130Abnormality of the renal medulla (HP:0100957)1.80551715
131Medial flaring of the eyebrow (HP:0010747)1.80539200
132Prolonged neonatal jaundice (HP:0006579)1.80197864
133Amniotic constriction ring (HP:0009775)1.79978298
134Abnormality of placental membranes (HP:0011409)1.79978298
135Myokymia (HP:0002411)1.79908137
136Leukodystrophy (HP:0002415)1.79611098
137Absent thumb (HP:0009777)1.79599380
138Pendular nystagmus (HP:0012043)1.78699284
139Abnormality of the ileum (HP:0001549)1.76778008
140Muscle fiber atrophy (HP:0100295)1.75997464
141Abnormality of the renal cortex (HP:0011035)1.73239005
142Hypothermia (HP:0002045)1.72387588
143Male pseudohermaphroditism (HP:0000037)1.71827911
144Abnormality of chromosome stability (HP:0003220)1.71174287
145Blindness (HP:0000618)1.69770589
146Pancytopenia (HP:0001876)1.69010349
147Furrowed tongue (HP:0000221)1.68594200
148Aplasia/Hypoplasia of the tongue (HP:0010295)1.68473844
149Hyperphosphaturia (HP:0003109)1.67328440
150Septo-optic dysplasia (HP:0100842)1.65636138
151Aplasia/Hypoplasia of the sacrum (HP:0008517)1.65061641
152Congenital primary aphakia (HP:0007707)1.63939040
153Cystic liver disease (HP:0006706)1.62683908
154Abolished electroretinogram (ERG) (HP:0000550)1.61663090
155Gait imbalance (HP:0002141)1.60883325
156Small hand (HP:0200055)1.59714442
157Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.59022572

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.76811346
2WEE14.12401297
3FRK3.48529484
4PNCK3.44575004
5VRK23.42032689
6TSSK63.38847490
7STK163.02193907
8EIF2AK12.91713656
9AKT32.71200080
10PLK42.64971866
11SRPK12.53383814
12NME22.01688411
13PLK32.01544393
14EIF2AK31.96612564
15NME11.89797248
16ARAF1.88804290
17CASK1.76047653
18BRSK21.73282563
19CCNB11.72054302
20MKNK21.70961862
21VRK11.61824426
22MARK11.57061743
23GRK11.47953694
24MKNK11.46508195
25BRAF1.36897503
26INSRR1.36439607
27EPHA21.36096521
28TNIK1.35702821
29BRSK11.33843553
30PLK11.33487896
31PDK41.31281463
32PDK31.31281463
33ZAK1.30805601
34PINK11.28539548
35ACVR1B1.25302169
36TRIM281.21082666
37MAP4K21.20077891
38NEK11.19494266
39PDK21.18268733
40DYRK21.15965908
41PLK21.12265311
42TAF11.12114447
43TTK1.11934291
44MAP3K121.08742654
45PIM21.07070038
46MST41.05301135
47AURKA1.04909621
48LATS21.03591417
49OXSR11.01812305
50BCR0.98724295
51MAP2K70.97888488
52CDK190.97715223
53TESK20.96724263
54TAOK30.96124393
55EPHA40.93466641
56PBK0.90307046
57IRAK30.87944575
58WNK40.87335383
59CSNK1G30.87329320
60TGFBR10.85212966
61DYRK30.85200595
62EIF2AK20.84573142
63CHEK20.83278290
64LIMK10.80787185
65GRK50.79763934
66STK38L0.79745811
67MUSK0.77534852
68NEK60.75370049
69PRKCG0.74965931
70STK390.74155874
71PHKG10.73637926
72PHKG20.73637926
73NEK20.72432853
74ADRBK10.67586588
75ERBB40.66886740
76BMPR20.66609681
77AURKB0.66265131
78PRKCI0.64089195
79MYLK0.62786227
80CDK80.62466902
81BCKDK0.61148131
82CSNK1G20.59860283
83OBSCN0.59747073
84CAMK2B0.59266578
85RPS6KA50.58052243
86WNK30.55982190
87CSNK1G10.55262087
88CAMKK20.54963181
89ATR0.54599556
90NTRK30.54413791
91CSNK2A10.53587170
92MAPK130.53317770
93BMPR1B0.53030293
94ABL20.52734978
95STK30.51246203
96CDK30.50805571
97PAK10.50639075
98PRKCE0.49330599
99CSNK2A20.48310793
100MAPKAPK50.46948888
101ERBB30.46945256
102CDC70.45588502
103STK240.44404641
104MAP3K90.43958362
105RAF10.42921315
106CDK140.42474708
107CSNK1A1L0.42437290
108GRK70.40057508
109ILK0.39622159
110CSNK1E0.39207837
111MAP3K40.38791945
112CAMK2G0.37898068
113ADRBK20.37374496
114ATM0.37077569
115TLK10.37066917
116CHEK10.36847370
117CDK180.36355583
118RIPK40.34138479
119CDK150.33975651
120CAMK2A0.32537124
121CSNK1A10.32474295
122PKN10.32303363
123CDK11A0.32024383
124STK40.31886518
125PIK3CG0.31129143
126IKBKB0.30889588
127MINK10.30867664
128PRKACA0.30637686
129NUAK10.30361410
130CAMK2D0.29492145

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030505.28411587
2RNA polymerase_Homo sapiens_hsa030205.12570428
3Vitamin B6 metabolism_Homo sapiens_hsa007504.42750248
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.68648196
5Ribosome_Homo sapiens_hsa030103.19086945
6Oxidative phosphorylation_Homo sapiens_hsa001903.03562035
7RNA transport_Homo sapiens_hsa030132.56986531
8Pyrimidine metabolism_Homo sapiens_hsa002402.54006025
9Parkinsons disease_Homo sapiens_hsa050122.51977223
10Basal transcription factors_Homo sapiens_hsa030222.38372419
11Spliceosome_Homo sapiens_hsa030402.29943332
12Regulation of autophagy_Homo sapiens_hsa041402.23673160
13Huntingtons disease_Homo sapiens_hsa050162.19219007
14Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.05437736
15Nucleotide excision repair_Homo sapiens_hsa034201.91167203
16DNA replication_Homo sapiens_hsa030301.88600173
17Homologous recombination_Homo sapiens_hsa034401.86049903
18Purine metabolism_Homo sapiens_hsa002301.79395671
19Alzheimers disease_Homo sapiens_hsa050101.71757373
20Collecting duct acid secretion_Homo sapiens_hsa049661.71544557
21Cell cycle_Homo sapiens_hsa041101.65469540
22Mismatch repair_Homo sapiens_hsa034301.60555392
23Protein export_Homo sapiens_hsa030601.58101535
24Fanconi anemia pathway_Homo sapiens_hsa034601.43578028
25Oocyte meiosis_Homo sapiens_hsa041141.35368079
26RNA degradation_Homo sapiens_hsa030181.31919058
27Nicotine addiction_Homo sapiens_hsa050331.29710129
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.20822428
29Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.20248875
30Epstein-Barr virus infection_Homo sapiens_hsa051691.11265993
31Base excision repair_Homo sapiens_hsa034101.09867974
32Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.08861578
33Sulfur metabolism_Homo sapiens_hsa009201.07694481
34Synaptic vesicle cycle_Homo sapiens_hsa047211.06368050
35Selenocompound metabolism_Homo sapiens_hsa004501.02606025
36Cardiac muscle contraction_Homo sapiens_hsa042600.99212781
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.98345677
38Glycerophospholipid metabolism_Homo sapiens_hsa005640.94489962
39Sulfur relay system_Homo sapiens_hsa041220.94149121
40Folate biosynthesis_Homo sapiens_hsa007900.93751428
41Propanoate metabolism_Homo sapiens_hsa006400.93340146
42Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.92947869
43Tryptophan metabolism_Homo sapiens_hsa003800.92654389
44SNARE interactions in vesicular transport_Homo sapiens_hsa041300.91306418
45Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.89149063
46Cysteine and methionine metabolism_Homo sapiens_hsa002700.89104495
47p53 signaling pathway_Homo sapiens_hsa041150.87480884
48Pentose phosphate pathway_Homo sapiens_hsa000300.86288903
49Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.86171564
50Butanoate metabolism_Homo sapiens_hsa006500.83096451
51Pyruvate metabolism_Homo sapiens_hsa006200.83034248
52Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.78130468
53Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.77885531
54mRNA surveillance pathway_Homo sapiens_hsa030150.75975208
55Vibrio cholerae infection_Homo sapiens_hsa051100.74089560
56Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.70923684
57Phototransduction_Homo sapiens_hsa047440.70771437
58Chemical carcinogenesis_Homo sapiens_hsa052040.70609893
59Nitrogen metabolism_Homo sapiens_hsa009100.69633621
60Rheumatoid arthritis_Homo sapiens_hsa053230.69536627
61Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.68698577
62Pentose and glucuronate interconversions_Homo sapiens_hsa000400.65716660
63Ether lipid metabolism_Homo sapiens_hsa005650.65579458
64Metabolic pathways_Homo sapiens_hsa011000.65524942
65Sphingolipid metabolism_Homo sapiens_hsa006000.64048370
66Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63863955
67Peroxisome_Homo sapiens_hsa041460.63047056
68Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.62597378
69Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.59934205
70* Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.59768230
71Non-homologous end-joining_Homo sapiens_hsa034500.59194372
72Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.58707623
73Primary bile acid biosynthesis_Homo sapiens_hsa001200.56517741
74Steroid biosynthesis_Homo sapiens_hsa001000.55691013
75Fatty acid elongation_Homo sapiens_hsa000620.54661357
76Arachidonic acid metabolism_Homo sapiens_hsa005900.54535269
77Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.52427469
78Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.52287362
79beta-Alanine metabolism_Homo sapiens_hsa004100.51915546
80Steroid hormone biosynthesis_Homo sapiens_hsa001400.51667361
81Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.51462359
82Amphetamine addiction_Homo sapiens_hsa050310.51400262
83Retinol metabolism_Homo sapiens_hsa008300.48975949
84Fructose and mannose metabolism_Homo sapiens_hsa000510.48021074
85Glutathione metabolism_Homo sapiens_hsa004800.47242943
86Linoleic acid metabolism_Homo sapiens_hsa005910.46602182
87Caffeine metabolism_Homo sapiens_hsa002320.46308871
88Circadian rhythm_Homo sapiens_hsa047100.45915462
89Serotonergic synapse_Homo sapiens_hsa047260.45104645
90GABAergic synapse_Homo sapiens_hsa047270.42070897
91Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.41130921
92Vitamin digestion and absorption_Homo sapiens_hsa049770.40105143
93Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.39347875
94Maturity onset diabetes of the young_Homo sapiens_hsa049500.37592535
95Taste transduction_Homo sapiens_hsa047420.35840914
96Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.33715128
97Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.30875813
98Glutamatergic synapse_Homo sapiens_hsa047240.30422820
99Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.29974300
100N-Glycan biosynthesis_Homo sapiens_hsa005100.28271805
101Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.25725624
102Systemic lupus erythematosus_Homo sapiens_hsa053220.25655577
103Drug metabolism - other enzymes_Homo sapiens_hsa009830.25590431
104Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.24655030
105Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.24207172
106Fatty acid degradation_Homo sapiens_hsa000710.23431941
107Long-term potentiation_Homo sapiens_hsa047200.22669601
108Phagosome_Homo sapiens_hsa041450.22469414
109Tyrosine metabolism_Homo sapiens_hsa003500.22357073
110Biosynthesis of amino acids_Homo sapiens_hsa012300.19793003
111Morphine addiction_Homo sapiens_hsa050320.18906884
112Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.18104583
113alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.17778234
114Arginine and proline metabolism_Homo sapiens_hsa003300.16131296
115Long-term depression_Homo sapiens_hsa047300.16068753
116Dopaminergic synapse_Homo sapiens_hsa047280.15950883
117Mineral absorption_Homo sapiens_hsa049780.14121942
118Autoimmune thyroid disease_Homo sapiens_hsa053200.13732252
119Carbon metabolism_Homo sapiens_hsa012000.11731865
120Circadian entrainment_Homo sapiens_hsa047130.10445590
121One carbon pool by folate_Homo sapiens_hsa006700.08758040
122Calcium signaling pathway_Homo sapiens_hsa040200.08118317
123Alcoholism_Homo sapiens_hsa050340.03947103
124Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.03692188
125Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.02234694
126Olfactory transduction_Homo sapiens_hsa047400.01586204
127Type I diabetes mellitus_Homo sapiens_hsa049400.01542085
128Renin-angiotensin system_Homo sapiens_hsa046140.00956699
129Graft-versus-host disease_Homo sapiens_hsa053320.00179254

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