

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | N-acetylneuraminate metabolic process (GO:0006054) | 8.41390598 |
| 2 | protoporphyrinogen IX metabolic process (GO:0046501) | 8.40311941 |
| 3 | positive regulation of histone deacetylation (GO:0031065) | 8.14971697 |
| 4 | centriole replication (GO:0007099) | 7.58130618 |
| 5 | regulation of MHC class II biosynthetic process (GO:0045346) | 7.26821555 |
| 6 | positive regulation of protein deacetylation (GO:0090312) | 7.24525060 |
| 7 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 7.03728952 |
| 8 | microglial cell activation (GO:0001774) | 6.76116654 |
| 9 | purine deoxyribonucleotide catabolic process (GO:0009155) | 6.19152659 |
| 10 | amino sugar catabolic process (GO:0046348) | 5.84537637 |
| 11 | neutrophil mediated immunity (GO:0002446) | 5.81985515 |
| 12 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 5.69076302 |
| 13 | N-acetylglucosamine metabolic process (GO:0006044) | 5.65415502 |
| 14 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 5.59351190 |
| 15 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 5.14135236 |
| 16 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 5.14135236 |
| 17 | reactive oxygen species biosynthetic process (GO:1903409) | 5.09202250 |
| 18 | base-excision repair, AP site formation (GO:0006285) | 5.04590323 |
| 19 | centriole assembly (GO:0098534) | 5.04433382 |
| 20 | negative regulation of phagocytosis (GO:0050765) | 4.98605544 |
| 21 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 4.91453284 |
| 22 | regulation of growth of symbiont in host (GO:0044126) | 4.91453284 |
| 23 | negative regulation of growth of symbiont in host (GO:0044130) | 4.91453284 |
| 24 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 4.91453284 |
| 25 | regulation of chemokine biosynthetic process (GO:0045073) | 4.89127744 |
| 26 | positive regulation of chemokine biosynthetic process (GO:0045080) | 4.85763905 |
| 27 | response to folic acid (GO:0051593) | 4.75558614 |
| 28 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 4.52169701 |
| 29 | regulation of histone deacetylation (GO:0031063) | 4.48210164 |
| 30 | thalamus development (GO:0021794) | 4.44900292 |
| 31 | myeloid leukocyte mediated immunity (GO:0002444) | 4.41709310 |
| 32 | cytokinetic process (GO:0032506) | 4.02410489 |
| 33 | negative regulation of interleukin-2 production (GO:0032703) | 3.98294012 |
| 34 | macrophage activation (GO:0042116) | 3.97981800 |
| 35 | respiratory burst (GO:0045730) | 3.95096301 |
| 36 | purine deoxyribonucleotide metabolic process (GO:0009151) | 3.90030917 |
| 37 | regulation of protein deacetylation (GO:0090311) | 3.73572241 |
| 38 | regulation of fatty acid transport (GO:2000191) | 3.69701681 |
| 39 | prostate gland growth (GO:0060736) | 3.65481080 |
| 40 | angiotensin maturation (GO:0002003) | 3.54569602 |
| 41 | glucosamine-containing compound metabolic process (GO:1901071) | 3.48313493 |
| 42 | positive regulation by symbiont of host defense response (GO:0052509) | 3.44968804 |
| 43 | modulation by symbiont of host defense response (GO:0052031) | 3.44968804 |
| 44 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.44968804 |
| 45 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.44968804 |
| 46 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.44968804 |
| 47 | modulation by symbiont of host immune response (GO:0052553) | 3.44968804 |
| 48 | defense response to fungus (GO:0050832) | 3.42175604 |
| 49 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.31165621 |
| 50 | early endosome to late endosome transport (GO:0045022) | 3.31065738 |
| 51 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.30359954 |
| 52 | ventricular system development (GO:0021591) | 3.30118110 |
| 53 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 3.27875227 |
| 54 | cellular response to ethanol (GO:0071361) | 3.27672834 |
| 55 | regulation of thymocyte apoptotic process (GO:0070243) | 3.26502727 |
| 56 | macrophage chemotaxis (GO:0048246) | 3.23944257 |
| 57 | regulation of protein import into nucleus, translocation (GO:0033158) | 3.23531134 |
| 58 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.22226584 |
| 59 | signal complex assembly (GO:0007172) | 3.22212714 |
| 60 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 3.20986863 |
| 61 | positive regulation of interleukin-1 beta production (GO:0032731) | 3.10276488 |
| 62 | regulation of erythrocyte differentiation (GO:0045646) | 3.08560782 |
| 63 | cellular response to cadmium ion (GO:0071276) | 3.04710707 |
| 64 | heme biosynthetic process (GO:0006783) | 3.00160779 |
| 65 | response to host immune response (GO:0052572) | 2.99967707 |
| 66 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.99967707 |
| 67 | positive regulation of interleukin-1 production (GO:0032732) | 2.99741095 |
| 68 | induction of positive chemotaxis (GO:0050930) | 2.97098232 |
| 69 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.96070464 |
| 70 | response to fungus (GO:0009620) | 2.93164046 |
| 71 | negative regulation of cell killing (GO:0031342) | 2.92630173 |
| 72 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.92630173 |
| 73 | positive regulation of erythrocyte differentiation (GO:0045648) | 2.88558236 |
| 74 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 2.85677269 |
| 75 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 2.85677269 |
| 76 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 2.84175098 |
| 77 | regulation of glycolytic process (GO:0006110) | 2.82228668 |
| 78 | CD4-positive, alpha-beta T cell activation (GO:0035710) | 2.82133757 |
| 79 | interferon-gamma production (GO:0032609) | 2.80276473 |
| 80 | positive regulation of histone H3-K4 methylation (GO:0051571) | 2.79434588 |
| 81 | response to misfolded protein (GO:0051788) | 2.71909720 |
| 82 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.68681664 |
| 83 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.67861657 |
| 84 | response to host (GO:0075136) | 2.67861657 |
| 85 | response to host defenses (GO:0052200) | 2.67861657 |
| 86 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.65053507 |
| 87 | positive regulation of mast cell degranulation (GO:0043306) | 2.65053507 |
| 88 | negative regulation of T cell mediated immunity (GO:0002710) | 2.58795637 |
| 89 | disruption of cells of other organism (GO:0044364) | 2.57410695 |
| 90 | killing of cells of other organism (GO:0031640) | 2.57410695 |
| 91 | porphyrin-containing compound biosynthetic process (GO:0006779) | 2.55336198 |
| 92 | interkinetic nuclear migration (GO:0022027) | 2.55036662 |
| 93 | somatic diversification of immune receptors (GO:0002200) | 2.53869573 |
| 94 | alpha-beta T cell differentiation (GO:0046632) | 2.52181847 |
| 95 | negative regulation of histone acetylation (GO:0035067) | 2.51992347 |
| 96 | positive regulation of mast cell activation (GO:0033005) | 2.51427139 |
| 97 | sodium-independent organic anion transport (GO:0043252) | 2.51085169 |
| 98 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 2.50274485 |
| 99 | cellular extravasation (GO:0045123) | 11.1655453 |
| 100 | protoporphyrinogen IX biosynthetic process (GO:0006782) | 10.4913913 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IGF1R_20145208_ChIP-Seq_DFB_Human | 4.70615116 |
| 2 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.75504735 |
| 3 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 3.63244490 |
| 4 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 3.08864205 |
| 5 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.91313780 |
| 6 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.78915395 |
| 7 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.65057855 |
| 8 | ER_23166858_ChIP-Seq_MCF-7_Human | 2.62952445 |
| 9 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.23425297 |
| 10 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.14725462 |
| 11 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.97283689 |
| 12 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.95662558 |
| 13 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.91670778 |
| 14 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.88993627 |
| 15 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.86372765 |
| 16 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.84980623 |
| 17 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.84963625 |
| 18 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.79285707 |
| 19 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.75899573 |
| 20 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.72162706 |
| 21 | FUS_26573619_Chip-Seq_HEK293_Human | 1.65421482 |
| 22 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.62944181 |
| 23 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.62727345 |
| 24 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.61079007 |
| 25 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.60345840 |
| 26 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.59347941 |
| 27 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.58900991 |
| 28 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.55948476 |
| 29 | RXR_22108803_ChIP-Seq_LS180_Human | 1.52402547 |
| 30 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.51390325 |
| 31 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.51126020 |
| 32 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.46613489 |
| 33 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.45552897 |
| 34 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.42509336 |
| 35 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.41545367 |
| 36 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.39972464 |
| 37 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.36386256 |
| 38 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.34362555 |
| 39 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.33014081 |
| 40 | STAT3_23295773_ChIP-Seq_U87_Human | 1.32291916 |
| 41 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.31316684 |
| 42 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.29743195 |
| 43 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.28441026 |
| 44 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.28441026 |
| 45 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.27922516 |
| 46 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.27625513 |
| 47 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.27522872 |
| 48 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.27163302 |
| 49 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.26196132 |
| 50 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.25952054 |
| 51 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.25497539 |
| 52 | EWS_26573619_Chip-Seq_HEK293_Human | 1.24891661 |
| 53 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.24418910 |
| 54 | SPI1_23127762_ChIP-Seq_K562_Human | 1.22603990 |
| 55 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.21971069 |
| 56 | TCF4_23295773_ChIP-Seq_U87_Human | 1.21167413 |
| 57 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.20722971 |
| 58 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.20683769 |
| 59 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.19030493 |
| 60 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.16660434 |
| 61 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.16083983 |
| 62 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.15743205 |
| 63 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.14540475 |
| 64 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.14517552 |
| 65 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.13727074 |
| 66 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.10896291 |
| 67 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.09294367 |
| 68 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.08522844 |
| 69 | MYB_26560356_Chip-Seq_TH2_Human | 1.07341520 |
| 70 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.06903419 |
| 71 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.06585894 |
| 72 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.04039008 |
| 73 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.03111201 |
| 74 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.03111201 |
| 75 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.02139991 |
| 76 | GATA3_26560356_Chip-Seq_TH2_Human | 1.02012240 |
| 77 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.99628756 |
| 78 | MYB_26560356_Chip-Seq_TH1_Human | 0.98743804 |
| 79 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.98552844 |
| 80 | AR_20517297_ChIP-Seq_VCAP_Human | 0.98055313 |
| 81 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.95385329 |
| 82 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.93307678 |
| 83 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.92702063 |
| 84 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.92670245 |
| 85 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.92567968 |
| 86 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.91908308 |
| 87 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.90725725 |
| 88 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.90436482 |
| 89 | P300_19829295_ChIP-Seq_ESCs_Human | 0.90413188 |
| 90 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.89303373 |
| 91 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.88926160 |
| 92 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.88773614 |
| 93 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.88671446 |
| 94 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.86673292 |
| 95 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.85688288 |
| 96 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.85522118 |
| 97 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.84961380 |
| 98 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.84336279 |
| 99 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.84336279 |
| 100 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.84323031 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005083_abnormal_biliary_tract | 7.46360312 |
| 2 | MP0003252_abnormal_bile_duct | 4.32140965 |
| 3 | MP0008961_abnormal_basal_metabolism | 4.29257752 |
| 4 | MP0008057_abnormal_DNA_replication | 4.05731114 |
| 5 | MP0005670_abnormal_white_adipose | 3.77553292 |
| 6 | MP0008058_abnormal_DNA_repair | 3.64244010 |
| 7 | MP0004043_abnormal_pH_regulation | 3.49216069 |
| 8 | MP0005365_abnormal_bile_salt | 2.76227908 |
| 9 | MP0005085_abnormal_gallbladder_physiolo | 2.58692613 |
| 10 | MP0005451_abnormal_body_composition | 2.54797798 |
| 11 | MP0002132_abnormal_respiratory_system | 2.48005367 |
| 12 | MP0000569_abnormal_digit_pigmentation | 2.46004852 |
| 13 | MP0001835_abnormal_antigen_presentation | 2.11791205 |
| 14 | MP0000003_abnormal_adipose_tissue | 2.05921250 |
| 15 | MP0000516_abnormal_urinary_system | 2.04191550 |
| 16 | MP0005367_renal/urinary_system_phenotyp | 2.04191550 |
| 17 | MP0003724_increased_susceptibility_to | 1.87639134 |
| 18 | MP0002419_abnormal_innate_immunity | 1.79522538 |
| 19 | MP0004742_abnormal_vestibular_system | 1.71645405 |
| 20 | MP0009278_abnormal_bone_marrow | 1.63433413 |
| 21 | MP0003303_peritoneal_inflammation | 1.57090382 |
| 22 | MP0001800_abnormal_humoral_immune | 1.55808144 |
| 23 | MP0004885_abnormal_endolymph | 1.52766817 |
| 24 | MP0003121_genomic_imprinting | 1.47419107 |
| 25 | MP0008877_abnormal_DNA_methylation | 1.46539235 |
| 26 | MP0009115_abnormal_fat_cell | 1.43595009 |
| 27 | MP0005375_adipose_tissue_phenotype | 1.42783289 |
| 28 | MP0002420_abnormal_adaptive_immunity | 1.41880943 |
| 29 | MP0005310_abnormal_salivary_gland | 1.41609064 |
| 30 | MP0001819_abnormal_immune_cell | 1.38938046 |
| 31 | MP0002452_abnormal_antigen_presenting | 1.34288991 |
| 32 | MP0005397_hematopoietic_system_phenotyp | 1.31493430 |
| 33 | MP0001545_abnormal_hematopoietic_system | 1.31493430 |
| 34 | MP0003436_decreased_susceptibility_to | 1.31227153 |
| 35 | MP0003195_calcinosis | 1.29177040 |
| 36 | MP0000685_abnormal_immune_system | 1.27077148 |
| 37 | MP0005025_abnormal_response_to | 1.25582891 |
| 38 | MP0010329_abnormal_lipoprotein_level | 1.19803024 |
| 39 | MP0002723_abnormal_immune_serum | 1.19317128 |
| 40 | MP0003123_paternal_imprinting | 1.19176859 |
| 41 | MP0003787_abnormal_imprinting | 1.17953440 |
| 42 | MP0005000_abnormal_immune_tolerance | 1.17166718 |
| 43 | MP0009785_altered_susceptibility_to | 1.17032956 |
| 44 | MP0004142_abnormal_muscle_tone | 1.15441106 |
| 45 | MP0000015_abnormal_ear_pigmentation | 1.14373977 |
| 46 | MP0002166_altered_tumor_susceptibility | 1.13088580 |
| 47 | MP0002398_abnormal_bone_marrow | 1.12275404 |
| 48 | MP0003221_abnormal_cardiomyocyte_apopto | 1.07087015 |
| 49 | MP0001501_abnormal_sleep_pattern | 1.05709283 |
| 50 | MP0005671_abnormal_response_to | 1.05672328 |
| 51 | MP0001502_abnormal_circadian_rhythm | 1.05294888 |
| 52 | MP0005387_immune_system_phenotype | 1.03441580 |
| 53 | MP0001790_abnormal_immune_system | 1.03441580 |
| 54 | MP0005464_abnormal_platelet_physiology | 1.03381916 |
| 55 | MP0000703_abnormal_thymus_morphology | 1.02424240 |
| 56 | MP0000716_abnormal_immune_system | 1.00754133 |
| 57 | MP0005266_abnormal_metabolism | 1.00558711 |
| 58 | MP0005174_abnormal_tail_pigmentation | 1.00104946 |
| 59 | MP0008872_abnormal_physiological_respon | 0.99435138 |
| 60 | MP0002396_abnormal_hematopoietic_system | 0.97877292 |
| 61 | MP0002127_abnormal_cardiovascular_syste | 0.96395347 |
| 62 | MP0005220_abnormal_exocrine_pancreas | 0.92511393 |
| 63 | MP0003172_abnormal_lysosome_physiology | 0.90675523 |
| 64 | MP0002722_abnormal_immune_system | 0.89721212 |
| 65 | MP0002405_respiratory_system_inflammati | 0.89422061 |
| 66 | MP0000689_abnormal_spleen_morphology | 0.87080392 |
| 67 | MP0004947_skin_inflammation | 0.84337367 |
| 68 | MP0002006_tumorigenesis | 0.84092728 |
| 69 | MP0001529_abnormal_vocalization | 0.83187536 |
| 70 | MP0000383_abnormal_hair_follicle | 0.83138022 |
| 71 | MP0002693_abnormal_pancreas_physiology | 0.82528618 |
| 72 | MP0003763_abnormal_thymus_physiology | 0.79601396 |
| 73 | MP0005164_abnormal_response_to | 0.79232855 |
| 74 | MP0002095_abnormal_skin_pigmentation | 0.78362141 |
| 75 | MP0005551_abnormal_eye_electrophysiolog | 0.74418180 |
| 76 | MP0008007_abnormal_cellular_replicative | 0.73436666 |
| 77 | MP0002429_abnormal_blood_cell | 0.72994205 |
| 78 | MP0001845_abnormal_inflammatory_respons | 0.72925812 |
| 79 | MP0002933_joint_inflammation | 0.72645170 |
| 80 | MP0001919_abnormal_reproductive_system | 0.72346082 |
| 81 | MP0002876_abnormal_thyroid_physiology | 0.72002271 |
| 82 | MP0003828_pulmonary_edema | 0.69144779 |
| 83 | MP0000465_gastrointestinal_hemorrhage | 0.66721662 |
| 84 | MP0002970_abnormal_white_adipose | 0.65376163 |
| 85 | MP0005334_abnormal_fat_pad | 0.65074536 |
| 86 | MP0005379_endocrine/exocrine_gland_phen | 0.64527881 |
| 87 | MP0010678_abnormal_skin_adnexa | 0.64021404 |
| 88 | MP0010307_abnormal_tumor_latency | 0.63318107 |
| 89 | MP0001270_distended_abdomen | 0.62874947 |
| 90 | MP0004808_abnormal_hematopoietic_stem | 0.61691615 |
| 91 | MP0003786_premature_aging | 0.60637872 |
| 92 | MP0003690_abnormal_glial_cell | 0.58527652 |
| 93 | MP0002163_abnormal_gland_morphology | 0.58503264 |
| 94 | MP0000955_abnormal_spinal_cord | 0.57461824 |
| 95 | MP0009643_abnormal_urine_homeostasis | 0.56563746 |
| 96 | MP0003567_abnormal_fetal_cardiomyocyte | 0.55832252 |
| 97 | MP0002928_abnormal_bile_duct | 0.55785823 |
| 98 | MP0008875_abnormal_xenobiotic_pharmacok | 0.55073700 |
| 99 | MP0005448_abnormal_energy_balance | 0.53538182 |
| 100 | MP0000427_abnormal_hair_cycle | 0.52081381 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | B lymphocytopenia (HP:0010976) | 5.84802517 |
| 2 | Panhypogammaglobulinemia (HP:0003139) | 5.30133994 |
| 3 | Abnormality of B cell number (HP:0010975) | 5.27085942 |
| 4 | Thyroiditis (HP:0100646) | 5.24379685 |
| 5 | Severe combined immunodeficiency (HP:0004430) | 5.17785026 |
| 6 | Hypoproteinemia (HP:0003075) | 4.52359240 |
| 7 | Hypoplasia of the thymus (HP:0000778) | 4.46621549 |
| 8 | Combined immunodeficiency (HP:0005387) | 4.00601100 |
| 9 | T lymphocytopenia (HP:0005403) | 3.88685911 |
| 10 | Abnormality of the prostate (HP:0008775) | 3.78801998 |
| 11 | Eosinophilia (HP:0001880) | 3.54551026 |
| 12 | Papillary thyroid carcinoma (HP:0002895) | 3.42239743 |
| 13 | Abnormality of T cell number (HP:0011839) | 3.40449358 |
| 14 | Chest pain (HP:0100749) | 3.39966379 |
| 15 | Abnormality of eosinophils (HP:0001879) | 3.35326081 |
| 16 | Chronic obstructive pulmonary disease (HP:0006510) | 3.30902592 |
| 17 | Obstructive lung disease (HP:0006536) | 3.30902592 |
| 18 | Recurrent fungal infections (HP:0002841) | 3.29522601 |
| 19 | Granulocytopenia (HP:0001913) | 3.28293381 |
| 20 | Hypokalemic alkalosis (HP:0001949) | 3.23703287 |
| 21 | Meningitis (HP:0001287) | 3.19876410 |
| 22 | Cutaneous photosensitivity (HP:0000992) | 3.14497659 |
| 23 | Metabolic alkalosis (HP:0200114) | 3.12983190 |
| 24 | Generalized hyperpigmentation (HP:0007440) | 3.02938871 |
| 25 | Severe global developmental delay (HP:0011344) | 2.99677828 |
| 26 | Abnormality of chloride homeostasis (HP:0011422) | 2.94252482 |
| 27 | Protruding tongue (HP:0010808) | 2.94000361 |
| 28 | Myositis (HP:0100614) | 2.92501134 |
| 29 | Subacute progressive viral hepatitis (HP:0006572) | 2.92240773 |
| 30 | Recurrent bacterial skin infections (HP:0005406) | 2.86449192 |
| 31 | Hemoptysis (HP:0002105) | 2.82949180 |
| 32 | Failure to thrive in infancy (HP:0001531) | 2.77228196 |
| 33 | Neoplasm of the adrenal cortex (HP:0100641) | 2.69121578 |
| 34 | Adactyly (HP:0009776) | 2.63937390 |
| 35 | Leukocytosis (HP:0001974) | 2.59181641 |
| 36 | Febrile seizures (HP:0002373) | 2.58115447 |
| 37 | Thyroid carcinoma (HP:0002890) | 2.56662160 |
| 38 | Recurrent viral infections (HP:0004429) | 2.52523454 |
| 39 | Optic neuritis (HP:0100653) | 2.50333951 |
| 40 | Retrobulbar optic neuritis (HP:0100654) | 2.50333951 |
| 41 | Absent speech (HP:0001344) | 2.45675775 |
| 42 | Pulmonary infiltrates (HP:0002113) | 2.44079425 |
| 43 | Fair hair (HP:0002286) | 2.42975619 |
| 44 | Porencephaly (HP:0002132) | 2.40218801 |
| 45 | Sepsis (HP:0100806) | 2.37230671 |
| 46 | Gangrene (HP:0100758) | 2.36682940 |
| 47 | Recurrent abscess formation (HP:0002722) | 2.36321286 |
| 48 | Neonatal respiratory distress (HP:0002643) | 2.32350541 |
| 49 | Erythroderma (HP:0001019) | 2.31973029 |
| 50 | Abnormality of T cells (HP:0002843) | 2.29332155 |
| 51 | Viral hepatitis (HP:0006562) | 2.25787945 |
| 52 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.23551753 |
| 53 | Orchitis (HP:0100796) | 2.19876265 |
| 54 | Generalized hypopigmentation of hair (HP:0011358) | 2.19856415 |
| 55 | Abnormality of male internal genitalia (HP:0000022) | 2.19682118 |
| 56 | Medial flaring of the eyebrow (HP:0010747) | 2.14850350 |
| 57 | Ureteral obstruction (HP:0006000) | 2.12207460 |
| 58 | Episodic fever (HP:0001954) | 2.11983764 |
| 59 | Pulmonary embolism (HP:0002204) | 2.11063103 |
| 60 | Stomatitis (HP:0010280) | 2.09785772 |
| 61 | Abnormal ciliary motility (HP:0012262) | 2.09304642 |
| 62 | Prostate neoplasm (HP:0100787) | 2.05153352 |
| 63 | IgG deficiency (HP:0004315) | 2.01658063 |
| 64 | Arterial thrombosis (HP:0004420) | 2.00382695 |
| 65 | Hyperaldosteronism (HP:0000859) | 1.98104337 |
| 66 | Flat occiput (HP:0005469) | 1.97932754 |
| 67 | Ureteral stenosis (HP:0000071) | 1.97187985 |
| 68 | Prominent metopic ridge (HP:0005487) | 1.95537479 |
| 69 | Eczematoid dermatitis (HP:0000976) | 1.94427832 |
| 70 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.89046995 |
| 71 | Vasculitis (HP:0002633) | 1.87968079 |
| 72 | Neonatal hypoglycemia (HP:0001998) | 1.87645348 |
| 73 | Renal cell carcinoma (HP:0005584) | 1.86830467 |
| 74 | Lissencephaly (HP:0001339) | 1.86665036 |
| 75 | Keratoconjunctivitis sicca (HP:0001097) | 1.86519626 |
| 76 | Excessive salivation (HP:0003781) | 1.84583557 |
| 77 | Hematochezia (HP:0002573) | 1.84374686 |
| 78 | Renal salt wasting (HP:0000127) | 1.84285901 |
| 79 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.83246438 |
| 80 | Attenuation of retinal blood vessels (HP:0007843) | 1.81609337 |
| 81 | Inappropriate behavior (HP:0000719) | 1.81448201 |
| 82 | Recurrent skin infections (HP:0001581) | 1.79799863 |
| 83 | Drooling (HP:0002307) | 1.79724889 |
| 84 | Abnormality of the pleura (HP:0002103) | 1.78438158 |
| 85 | Intestinal atresia (HP:0011100) | 1.78366040 |
| 86 | Widely spaced teeth (HP:0000687) | 1.78118353 |
| 87 | Abnormality of the metopic suture (HP:0005556) | 1.77477034 |
| 88 | Thrombophlebitis (HP:0004418) | 1.77400132 |
| 89 | Abnormality of the renal cortex (HP:0011035) | 1.76159955 |
| 90 | Hyperkalemia (HP:0002153) | 1.75464603 |
| 91 | Tubulointerstitial fibrosis (HP:0005576) | 1.73546791 |
| 92 | Broad-based gait (HP:0002136) | 1.73197688 |
| 93 | Keratoconjunctivitis (HP:0001096) | 1.71194274 |
| 94 | Progressive cerebellar ataxia (HP:0002073) | 1.71055244 |
| 95 | Skin rash (HP:0000988) | 1.70398900 |
| 96 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.70061156 |
| 97 | Gastrointestinal infarctions (HP:0005244) | 1.69175075 |
| 98 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.68559666 |
| 99 | Abnormality of chromosome stability (HP:0003220) | 1.68398790 |
| 100 | Gaze-evoked nystagmus (HP:0000640) | 1.68112502 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CCNB1 | 8.24328341 |
| 2 | NEK2 | 5.63051045 |
| 3 | TAF1 | 5.30456151 |
| 4 | CAMKK2 | 4.40697099 |
| 5 | CAMK1D | 3.46893937 |
| 6 | CAMK1G | 2.61368072 |
| 7 | ERN1 | 2.47524169 |
| 8 | FRK | 2.14795169 |
| 9 | SMG1 | 2.12587067 |
| 10 | CAMKK1 | 1.74971127 |
| 11 | MAP3K7 | 1.64547915 |
| 12 | TXK | 1.58428137 |
| 13 | NUAK1 | 1.45698124 |
| 14 | VRK2 | 1.40712695 |
| 15 | CHUK | 1.39257378 |
| 16 | FGFR3 | 1.37267748 |
| 17 | LRRK2 | 1.27425628 |
| 18 | WNK4 | 1.16564321 |
| 19 | MARK2 | 1.15000054 |
| 20 | SYK | 1.12937496 |
| 21 | CAMK1 | 1.11501584 |
| 22 | SGK2 | 1.04865075 |
| 23 | NTRK3 | 1.04555296 |
| 24 | EPHB1 | 1.04097160 |
| 25 | CSK | 1.01818099 |
| 26 | TAOK3 | 1.01695426 |
| 27 | ZAP70 | 1.00740573 |
| 28 | KSR2 | 0.97877765 |
| 29 | PRPF4B | 0.97557410 |
| 30 | MAP4K1 | 0.96008410 |
| 31 | WNK1 | 0.95570640 |
| 32 | TRIM28 | 0.92551948 |
| 33 | IKBKE | 0.88946092 |
| 34 | DYRK1A | 0.85514064 |
| 35 | MAPK13 | 0.82454128 |
| 36 | TNK2 | 0.80263464 |
| 37 | CAMK4 | 0.73754510 |
| 38 | RAF1 | 0.72957556 |
| 39 | HCK | 0.71318256 |
| 40 | BTK | 0.69063076 |
| 41 | TEC | 0.66217295 |
| 42 | MAP3K2 | 0.65665371 |
| 43 | HIPK2 | 0.63413383 |
| 44 | MATK | 0.63376681 |
| 45 | TESK2 | 0.61143005 |
| 46 | MAP2K3 | 0.61090437 |
| 47 | TYK2 | 0.59360865 |
| 48 | STK11 | 0.58250268 |
| 49 | NLK | 0.57625172 |
| 50 | SGK494 | 0.57146329 |
| 51 | SGK223 | 0.57146329 |
| 52 | ITK | 0.56713589 |
| 53 | SGK3 | 0.56040180 |
| 54 | NTRK2 | 0.55079750 |
| 55 | RIPK4 | 0.54203788 |
| 56 | IRAK4 | 0.53551988 |
| 57 | BLK | 0.53543492 |
| 58 | SGK1 | 0.52594509 |
| 59 | MAP3K4 | 0.52003559 |
| 60 | KIT | 0.51967077 |
| 61 | LYN | 0.51610798 |
| 62 | CLK1 | 0.51186565 |
| 63 | GRK5 | 0.50833572 |
| 64 | WNK3 | 0.50802383 |
| 65 | PRKAA2 | 0.49755060 |
| 66 | JAK2 | 0.48331086 |
| 67 | KSR1 | 0.48214599 |
| 68 | IRAK2 | 0.45061584 |
| 69 | LCK | 0.42231764 |
| 70 | MAPK4 | 0.40126468 |
| 71 | MAP3K6 | 0.40096841 |
| 72 | GRK6 | 0.39385297 |
| 73 | OXSR1 | 0.38883723 |
| 74 | PIK3CG | 0.37890638 |
| 75 | IRAK1 | 0.37311141 |
| 76 | YES1 | 0.36349724 |
| 77 | BRAF | 0.34536175 |
| 78 | RPS6KB2 | 0.34270888 |
| 79 | ERBB3 | 0.33385049 |
| 80 | AKT3 | 0.31282186 |
| 81 | JAK3 | 0.30417137 |
| 82 | EIF2AK2 | 0.29868323 |
| 83 | DYRK2 | 0.29528832 |
| 84 | RPS6KA4 | 0.29181409 |
| 85 | MKNK2 | 0.28129434 |
| 86 | CSNK1G1 | 0.27894166 |
| 87 | PAK3 | 0.26914635 |
| 88 | MAP2K4 | 0.26524521 |
| 89 | PASK | 0.25535890 |
| 90 | GRK7 | 0.24782038 |
| 91 | MAPKAPK5 | 0.23227455 |
| 92 | FES | 0.22950565 |
| 93 | PDGFRB | 0.22715769 |
| 94 | ERBB2 | 0.22474645 |
| 95 | RPS6KB1 | 0.22318294 |
| 96 | DYRK1B | 0.21939786 |
| 97 | FGFR2 | 0.20896754 |
| 98 | CDK9 | 0.20886929 |
| 99 | PDK1 | 0.20463014 |
| 100 | IKBKB | 0.20211920 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 3.12388279 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.61275558 |
| 3 | Renin-angiotensin system_Homo sapiens_hsa04614 | 2.52613750 |
| 4 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.20184200 |
| 5 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 2.14456137 |
| 6 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.08290348 |
| 7 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.88702232 |
| 8 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.88541812 |
| 9 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.84684037 |
| 10 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.81231035 |
| 11 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.76922590 |
| 12 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.75058581 |
| 13 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.68999552 |
| 14 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.65799144 |
| 15 | Taste transduction_Homo sapiens_hsa04742 | 1.47638370 |
| 16 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.39026968 |
| 17 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.37914697 |
| 18 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.37207032 |
| 19 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.36103008 |
| 20 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.35938929 |
| 21 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.33610010 |
| 22 | Phototransduction_Homo sapiens_hsa04744 | 1.25822870 |
| 23 | Tuberculosis_Homo sapiens_hsa05152 | 1.24505625 |
| 24 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.20871587 |
| 25 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.20447794 |
| 26 | Phagosome_Homo sapiens_hsa04145 | 1.17869884 |
| 27 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.15995759 |
| 28 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.13718347 |
| 29 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.09970004 |
| 30 | Basal transcription factors_Homo sapiens_hsa03022 | 1.09417711 |
| 31 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.08901362 |
| 32 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.08632868 |
| 33 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.06986075 |
| 34 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.05622778 |
| 35 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.05197050 |
| 36 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.04004061 |
| 37 | Leishmaniasis_Homo sapiens_hsa05140 | 1.02274405 |
| 38 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.01805131 |
| 39 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.98763077 |
| 40 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.97977784 |
| 41 | Platelet activation_Homo sapiens_hsa04611 | 0.97578565 |
| 42 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.97056115 |
| 43 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.95287805 |
| 44 | Axon guidance_Homo sapiens_hsa04360 | 0.93750067 |
| 45 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.92914715 |
| 46 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.91284842 |
| 47 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.90637523 |
| 48 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.89880870 |
| 49 | Long-term depression_Homo sapiens_hsa04730 | 0.85850230 |
| 50 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.85668978 |
| 51 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.84185300 |
| 52 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.83612356 |
| 53 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.82276727 |
| 54 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.81362532 |
| 55 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.80888411 |
| 56 | Lysosome_Homo sapiens_hsa04142 | 0.78268990 |
| 57 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.78150652 |
| 58 | Glioma_Homo sapiens_hsa05214 | 0.78043652 |
| 59 | Thyroid cancer_Homo sapiens_hsa05216 | 0.77066992 |
| 60 | Histidine metabolism_Homo sapiens_hsa00340 | 0.76425812 |
| 61 | Morphine addiction_Homo sapiens_hsa05032 | 0.75638801 |
| 62 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.74508833 |
| 63 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.74438873 |
| 64 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.73446512 |
| 65 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.72184988 |
| 66 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.71676985 |
| 67 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.69465037 |
| 68 | Endometrial cancer_Homo sapiens_hsa05213 | 0.68988323 |
| 69 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.68888852 |
| 70 | Olfactory transduction_Homo sapiens_hsa04740 | 0.67021731 |
| 71 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.65364112 |
| 72 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.63838391 |
| 73 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.62027635 |
| 74 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.60132443 |
| 75 | Long-term potentiation_Homo sapiens_hsa04720 | 0.60091210 |
| 76 | Nicotine addiction_Homo sapiens_hsa05033 | 0.59642496 |
| 77 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.57992413 |
| 78 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.57533431 |
| 79 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.56737931 |
| 80 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.56079453 |
| 81 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.55883007 |
| 82 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.50784421 |
| 83 | Legionellosis_Homo sapiens_hsa05134 | 0.49509040 |
| 84 | Hepatitis B_Homo sapiens_hsa05161 | 0.49498803 |
| 85 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.49031627 |
| 86 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.48335330 |
| 87 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.47343354 |
| 88 | Measles_Homo sapiens_hsa05162 | 0.47100077 |
| 89 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.47056896 |
| 90 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.46575165 |
| 91 | Melanoma_Homo sapiens_hsa05218 | 0.45235586 |
| 92 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.44496433 |
| 93 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.43266620 |
| 94 | Homologous recombination_Homo sapiens_hsa03440 | 0.42666268 |
| 95 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.41902551 |
| 96 | Colorectal cancer_Homo sapiens_hsa05210 | 0.41765643 |
| 97 | Malaria_Homo sapiens_hsa05144 | 0.41522529 |
| 98 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.41423464 |
| 99 | ABC transporters_Homo sapiens_hsa02010 | 0.40621656 |
| 100 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.40208421 |

