

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of retinoic acid receptor signaling pathway (GO:0048387) | 7.46258769 |
| 2 | DNA deamination (GO:0045006) | 6.77469502 |
| 3 | cytidine deamination (GO:0009972) | 6.48928426 |
| 4 | cytidine metabolic process (GO:0046087) | 6.48928426 |
| 5 | cytidine catabolic process (GO:0006216) | 6.48928426 |
| 6 | regulation of retinoic acid receptor signaling pathway (GO:0048385) | 6.30400137 |
| 7 | ribosomal small subunit assembly (GO:0000028) | 5.76067185 |
| 8 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.53516151 |
| 9 | chaperone-mediated protein transport (GO:0072321) | 5.49741653 |
| 10 | maturation of SSU-rRNA (GO:0030490) | 5.36062085 |
| 11 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.00814008 |
| 12 | male meiosis I (GO:0007141) | 4.61971290 |
| 13 | ATP synthesis coupled proton transport (GO:0015986) | 4.33354513 |
| 14 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.33354513 |
| 15 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.32014830 |
| 16 | ribosomal small subunit biogenesis (GO:0042274) | 4.20023528 |
| 17 | viral transcription (GO:0019083) | 4.13048627 |
| 18 | pseudouridine synthesis (GO:0001522) | 4.09615423 |
| 19 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.02982852 |
| 20 | electron transport chain (GO:0022900) | 4.01664272 |
| 21 | negative regulation of telomere maintenance (GO:0032205) | 3.98634379 |
| 22 | translational termination (GO:0006415) | 3.98432918 |
| 23 | respiratory electron transport chain (GO:0022904) | 3.98407012 |
| 24 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.89286384 |
| 25 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.80235279 |
| 26 | meiosis I (GO:0007127) | 3.76528848 |
| 27 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.74347854 |
| 28 | piRNA metabolic process (GO:0034587) | 3.68318669 |
| 29 | translational elongation (GO:0006414) | 3.65731221 |
| 30 | regulation of meiosis I (GO:0060631) | 3.65655425 |
| 31 | regulation of chronic inflammatory response (GO:0002676) | 3.65382009 |
| 32 | sequestering of actin monomers (GO:0042989) | 3.64406896 |
| 33 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.64241543 |
| 34 | behavioral response to nicotine (GO:0035095) | 3.62707390 |
| 35 | cotranslational protein targeting to membrane (GO:0006613) | 3.57259670 |
| 36 | protein targeting to ER (GO:0045047) | 3.53453261 |
| 37 | protein complex biogenesis (GO:0070271) | 3.49315617 |
| 38 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.35474593 |
| 39 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.33617359 |
| 40 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.33272144 |
| 41 | NADH dehydrogenase complex assembly (GO:0010257) | 3.33272144 |
| 42 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.33272144 |
| 43 | protein localization to endoplasmic reticulum (GO:0070972) | 3.32409728 |
| 44 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.27094156 |
| 45 | ubiquinone biosynthetic process (GO:0006744) | 3.24076203 |
| 46 | rRNA modification (GO:0000154) | 3.20062059 |
| 47 | positive regulation of respiratory burst (GO:0060267) | 3.17476097 |
| 48 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.10563020 |
| 49 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.07430846 |
| 50 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.07430846 |
| 51 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.07344505 |
| 52 | hydrogen ion transmembrane transport (GO:1902600) | 3.05389804 |
| 53 | regulation of cellular respiration (GO:0043457) | 3.02259602 |
| 54 | negative regulation by host of viral transcription (GO:0043922) | 3.01980116 |
| 55 | cellular protein complex disassembly (GO:0043624) | 2.99897351 |
| 56 | translation (GO:0006412) | 2.99783435 |
| 57 | DNA demethylation (GO:0080111) | 2.98602177 |
| 58 | viral life cycle (GO:0019058) | 2.94754138 |
| 59 | protein neddylation (GO:0045116) | 2.91518625 |
| 60 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.90276183 |
| 61 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.88632314 |
| 62 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.85686006 |
| 63 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.85021386 |
| 64 | regulation of activation of Janus kinase activity (GO:0010533) | 2.84517381 |
| 65 | negative regulation of mast cell activation (GO:0033004) | 2.84228085 |
| 66 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.83998030 |
| 67 | transcription from mitochondrial promoter (GO:0006390) | 2.83843234 |
| 68 | protein-cofactor linkage (GO:0018065) | 2.83797819 |
| 69 | proton transport (GO:0015992) | 2.83665444 |
| 70 | rRNA processing (GO:0006364) | 2.81805966 |
| 71 | ubiquinone metabolic process (GO:0006743) | 2.81387678 |
| 72 | hydrogen transport (GO:0006818) | 2.76252422 |
| 73 | translational initiation (GO:0006413) | 2.75862851 |
| 74 | base-excision repair, AP site formation (GO:0006285) | 2.74766848 |
| 75 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.74486820 |
| 76 | male meiosis (GO:0007140) | 2.74420402 |
| 77 | rRNA metabolic process (GO:0016072) | 2.72210465 |
| 78 | maturation of 5.8S rRNA (GO:0000460) | 2.69294855 |
| 79 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.66752035 |
| 80 | termination of RNA polymerase III transcription (GO:0006386) | 2.66752035 |
| 81 | positive regulation of prostaglandin secretion (GO:0032308) | 2.66455188 |
| 82 | spliceosomal complex assembly (GO:0000245) | 2.66285226 |
| 83 | quinone biosynthetic process (GO:1901663) | 2.64114812 |
| 84 | positive regulation of T cell apoptotic process (GO:0070234) | 2.63102604 |
| 85 | negative regulation of meiosis (GO:0045835) | 2.59815001 |
| 86 | respiratory chain complex IV assembly (GO:0008535) | 2.59698943 |
| 87 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.58045647 |
| 88 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.56220660 |
| 89 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.56159116 |
| 90 | cellular ketone body metabolic process (GO:0046950) | 2.53614232 |
| 91 | platelet dense granule organization (GO:0060155) | 2.53003583 |
| 92 | regulation of mitochondrial translation (GO:0070129) | 2.52534618 |
| 93 | multicellular organism reproduction (GO:0032504) | 2.52290105 |
| 94 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.52281919 |
| 95 | tRNA processing (GO:0008033) | 2.50468254 |
| 96 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.49159046 |
| 97 | protein targeting to mitochondrion (GO:0006626) | 2.48346364 |
| 98 | cellular component biogenesis (GO:0044085) | 2.47898635 |
| 99 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.47223487 |
| 100 | protein K6-linked ubiquitination (GO:0085020) | 2.47164443 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.82491789 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.08053988 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.73543095 |
| 4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.49621676 |
| 5 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.34204025 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.25787148 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.92145460 |
| 8 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.92052070 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.78934953 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.78930771 |
| 11 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.73994721 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.71385930 |
| 13 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.63870863 |
| 14 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.55229818 |
| 15 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.50401412 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.45687645 |
| 17 | VDR_22108803_ChIP-Seq_LS180_Human | 2.27770867 |
| 18 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.99894055 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.89989419 |
| 20 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.84538483 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.77718620 |
| 22 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.63604021 |
| 23 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.61154905 |
| 24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.56905865 |
| 25 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.55550697 |
| 26 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.50873032 |
| 27 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.49173861 |
| 28 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.48434801 |
| 29 | ERA_21632823_ChIP-Seq_H3396_Human | 1.47801670 |
| 30 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.45209687 |
| 31 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.44547741 |
| 32 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.41357281 |
| 33 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.41310811 |
| 34 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.40418956 |
| 35 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.39938758 |
| 36 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.35671990 |
| 37 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.35495326 |
| 38 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.34054981 |
| 39 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.33736554 |
| 40 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.29301806 |
| 41 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.28637211 |
| 42 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.28275956 |
| 43 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.28192757 |
| 44 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.28081521 |
| 45 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.27012830 |
| 46 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.26563991 |
| 47 | AR_20517297_ChIP-Seq_VCAP_Human | 1.23003637 |
| 48 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.20199667 |
| 49 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.19947879 |
| 50 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.19521122 |
| 51 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.18982403 |
| 52 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.18841648 |
| 53 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.18120536 |
| 54 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.16848840 |
| 55 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.13969817 |
| 56 | GATA3_26560356_Chip-Seq_TH2_Human | 1.12957602 |
| 57 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.12131240 |
| 58 | NCOR_22424771_ChIP-Seq_293T_Human | 1.11651337 |
| 59 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.10814672 |
| 60 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.09612440 |
| 61 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.07941128 |
| 62 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.05586553 |
| 63 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04357825 |
| 64 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.02396202 |
| 65 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.02169437 |
| 66 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.02071622 |
| 67 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.01156306 |
| 68 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.99662542 |
| 69 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.98443234 |
| 70 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.98301719 |
| 71 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.97491333 |
| 72 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.97483846 |
| 73 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.97359971 |
| 74 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.97017660 |
| 75 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.96940601 |
| 76 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.96196738 |
| 77 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.94884184 |
| 78 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.94698478 |
| 79 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.94562991 |
| 80 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.94320380 |
| 81 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.94320380 |
| 82 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.92824281 |
| 83 | EWS_26573619_Chip-Seq_HEK293_Human | 0.92721877 |
| 84 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.91280644 |
| 85 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.91103418 |
| 86 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.90920919 |
| 87 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.90874884 |
| 88 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.90475069 |
| 89 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.89834943 |
| 90 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.89616642 |
| 91 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.88674576 |
| 92 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.88173728 |
| 93 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.88064259 |
| 94 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.86511577 |
| 95 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.85745002 |
| 96 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.85102196 |
| 97 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.84927938 |
| 98 | P300_27268052_Chip-Seq_Bcells_Human | 0.84655682 |
| 99 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.83965957 |
| 100 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.83697537 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.49247869 |
| 2 | MP0004147_increased_porphyrin_level | 3.92467783 |
| 3 | MP0003646_muscle_fatigue | 3.44510974 |
| 4 | MP0006292_abnormal_olfactory_placode | 3.40110651 |
| 5 | MP0001986_abnormal_taste_sensitivity | 2.87658063 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.78743477 |
| 7 | MP0005671_abnormal_response_to | 2.75674567 |
| 8 | MP0008872_abnormal_physiological_respon | 2.71829915 |
| 9 | MP0001348_abnormal_lacrimal_gland | 2.57748262 |
| 10 | MP0004142_abnormal_muscle_tone | 2.22200980 |
| 11 | MP0002102_abnormal_ear_morphology | 2.18408372 |
| 12 | MP0002735_abnormal_chemical_nociception | 2.04854342 |
| 13 | MP0003718_maternal_effect | 1.95091786 |
| 14 | MP0004145_abnormal_muscle_electrophysio | 1.94510016 |
| 15 | MP0000566_synostosis | 1.88602096 |
| 16 | MP0002653_abnormal_ependyma_morphology | 1.88170491 |
| 17 | MP0008875_abnormal_xenobiotic_pharmacok | 1.77009952 |
| 18 | MP0005645_abnormal_hypothalamus_physiol | 1.72717690 |
| 19 | MP0005423_abnormal_somatic_nervous | 1.71279936 |
| 20 | MP0004742_abnormal_vestibular_system | 1.64690237 |
| 21 | MP0005389_reproductive_system_phenotype | 1.63912983 |
| 22 | MP0008058_abnormal_DNA_repair | 1.61822707 |
| 23 | MP0001905_abnormal_dopamine_level | 1.61574272 |
| 24 | MP0002160_abnormal_reproductive_system | 1.57240851 |
| 25 | MP0003693_abnormal_embryo_hatching | 1.56051003 |
| 26 | MP0004885_abnormal_endolymph | 1.53864141 |
| 27 | MP0008789_abnormal_olfactory_epithelium | 1.51533555 |
| 28 | MP0001919_abnormal_reproductive_system | 1.48297931 |
| 29 | MP0006276_abnormal_autonomic_nervous | 1.46645944 |
| 30 | MP0001968_abnormal_touch/_nociception | 1.45324156 |
| 31 | MP0009745_abnormal_behavioral_response | 1.40297455 |
| 32 | MP0009333_abnormal_splenocyte_physiolog | 1.33217899 |
| 33 | MP0009840_abnormal_foam_cell | 1.30881312 |
| 34 | MP0001485_abnormal_pinna_reflex | 1.28243522 |
| 35 | MP0002837_dystrophic_cardiac_calcinosis | 1.27929656 |
| 36 | MP0005646_abnormal_pituitary_gland | 1.26320922 |
| 37 | MP0005551_abnormal_eye_electrophysiolog | 1.26115335 |
| 38 | MP0002272_abnormal_nervous_system | 1.25247384 |
| 39 | MP0002210_abnormal_sex_determination | 1.22039172 |
| 40 | MP0005394_taste/olfaction_phenotype | 1.21279016 |
| 41 | MP0005499_abnormal_olfactory_system | 1.21279016 |
| 42 | MP0001440_abnormal_grooming_behavior | 1.19761225 |
| 43 | MP0002736_abnormal_nociception_after | 1.19582944 |
| 44 | MP0002163_abnormal_gland_morphology | 1.17932809 |
| 45 | MP0001835_abnormal_antigen_presentation | 1.17116894 |
| 46 | MP0003787_abnormal_imprinting | 1.16264059 |
| 47 | MP0006072_abnormal_retinal_apoptosis | 1.14346125 |
| 48 | MP0002733_abnormal_thermal_nociception | 1.12841286 |
| 49 | MP0006082_CNS_inflammation | 1.11469888 |
| 50 | MP0009046_muscle_twitch | 1.10330380 |
| 51 | MP0005167_abnormal_blood-brain_barrier | 1.10112868 |
| 52 | MP0002638_abnormal_pupillary_reflex | 1.09832576 |
| 53 | MP0003938_abnormal_ear_development | 1.09681472 |
| 54 | MP0009785_altered_susceptibility_to | 1.06068179 |
| 55 | MP0005257_abnormal_intraocular_pressure | 1.05905265 |
| 56 | MP0003137_abnormal_impulse_conducting | 1.05156292 |
| 57 | MP0002095_abnormal_skin_pigmentation | 1.04630945 |
| 58 | MP0002234_abnormal_pharynx_morphology | 1.04295883 |
| 59 | MP0002938_white_spotting | 1.03727314 |
| 60 | MP0002876_abnormal_thyroid_physiology | 1.03577259 |
| 61 | MP0001970_abnormal_pain_threshold | 1.02564280 |
| 62 | MP0001929_abnormal_gametogenesis | 1.02001545 |
| 63 | MP0002148_abnormal_hypersensitivity_rea | 1.01523096 |
| 64 | MP0003890_abnormal_embryonic-extraembry | 0.99601806 |
| 65 | MP0001873_stomach_inflammation | 0.97966930 |
| 66 | MP0006036_abnormal_mitochondrial_physio | 0.97877740 |
| 67 | MP0005410_abnormal_fertilization | 0.94449579 |
| 68 | MP0001790_abnormal_immune_system | 0.92752928 |
| 69 | MP0005387_immune_system_phenotype | 0.92752928 |
| 70 | MP0001486_abnormal_startle_reflex | 0.90596431 |
| 71 | MP0005636_abnormal_mineral_homeostasis | 0.90221688 |
| 72 | MP0006035_abnormal_mitochondrial_morpho | 0.88905668 |
| 73 | MP0002184_abnormal_innervation | 0.88605689 |
| 74 | MP0004924_abnormal_behavior | 0.86206894 |
| 75 | MP0005386_behavior/neurological_phenoty | 0.86206894 |
| 76 | MP0001119_abnormal_female_reproductive | 0.85382977 |
| 77 | MP0005670_abnormal_white_adipose | 0.84718763 |
| 78 | MP0003763_abnormal_thymus_physiology | 0.84180817 |
| 79 | MP0001502_abnormal_circadian_rhythm | 0.83211195 |
| 80 | MP0003878_abnormal_ear_physiology | 0.81903659 |
| 81 | MP0005377_hearing/vestibular/ear_phenot | 0.81903659 |
| 82 | MP0003186_abnormal_redox_activity | 0.80062939 |
| 83 | MP0001800_abnormal_humoral_immune | 0.79021795 |
| 84 | MP0003880_abnormal_central_pattern | 0.78514633 |
| 85 | MP0001984_abnormal_olfaction | 0.78159102 |
| 86 | MP0000631_abnormal_neuroendocrine_gland | 0.77560724 |
| 87 | MP0003195_calcinosis | 0.76870678 |
| 88 | MP0002277_abnormal_respiratory_mucosa | 0.76500664 |
| 89 | MP0002064_seizures | 0.75374405 |
| 90 | MP0000653_abnormal_sex_gland | 0.73698799 |
| 91 | MP0003786_premature_aging | 0.70919932 |
| 92 | MP0000049_abnormal_middle_ear | 0.70457692 |
| 93 | MP0002067_abnormal_sensory_capabilities | 0.69634761 |
| 94 | MP0000427_abnormal_hair_cycle | 0.69073506 |
| 95 | MP0001501_abnormal_sleep_pattern | 0.69059727 |
| 96 | MP0004957_abnormal_blastocyst_morpholog | 0.69013345 |
| 97 | MP0000026_abnormal_inner_ear | 0.68584990 |
| 98 | MP0001765_abnormal_ion_homeostasis | 0.67723811 |
| 99 | MP0005195_abnormal_posterior_eye | 0.67122765 |
| 100 | MP0002693_abnormal_pancreas_physiology | 0.65442649 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Birth length less than 3rd percentile (HP:0003561) | 6.11594446 |
| 2 | Breast hypoplasia (HP:0003187) | 4.08134496 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 3.71096802 |
| 4 | Abnormality of the labia minora (HP:0012880) | 3.69785422 |
| 5 | Mitochondrial inheritance (HP:0001427) | 3.64618150 |
| 6 | Aplastic anemia (HP:0001915) | 3.43118804 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.37045803 |
| 8 | Microretrognathia (HP:0000308) | 3.30868134 |
| 9 | Increased CSF lactate (HP:0002490) | 3.26762859 |
| 10 | Reticulocytopenia (HP:0001896) | 3.26293592 |
| 11 | Congenital stationary night blindness (HP:0007642) | 3.22446013 |
| 12 | Hepatocellular necrosis (HP:0001404) | 3.17795607 |
| 13 | Pancreatic cysts (HP:0001737) | 3.06305632 |
| 14 | Colon cancer (HP:0003003) | 3.00940984 |
| 15 | Abnormality of midbrain morphology (HP:0002418) | 2.99068822 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 2.99068822 |
| 17 | Patellar aplasia (HP:0006443) | 2.98923227 |
| 18 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.97262719 |
| 19 | Hepatic necrosis (HP:0002605) | 2.93942476 |
| 20 | Progressive macrocephaly (HP:0004481) | 2.93431394 |
| 21 | 3-Methylglutaconic aciduria (HP:0003535) | 2.85232068 |
| 22 | Acute encephalopathy (HP:0006846) | 2.81639259 |
| 23 | Pendular nystagmus (HP:0012043) | 2.81007981 |
| 24 | Absent thumb (HP:0009777) | 2.74494550 |
| 25 | Increased hepatocellular lipid droplets (HP:0006565) | 2.65962014 |
| 26 | Myokymia (HP:0002411) | 2.61129403 |
| 27 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.60938042 |
| 28 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.57470697 |
| 29 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.57470697 |
| 30 | Abnormality of T cell number (HP:0011839) | 2.53101724 |
| 31 | Autoimmune thrombocytopenia (HP:0001973) | 2.47390937 |
| 32 | Abnormality of DNA repair (HP:0003254) | 2.46956548 |
| 33 | Oral leukoplakia (HP:0002745) | 2.46256656 |
| 34 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 2.43823650 |
| 35 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.43459862 |
| 36 | Pancreatic fibrosis (HP:0100732) | 2.39603146 |
| 37 | Type II lissencephaly (HP:0007260) | 2.36749623 |
| 38 | Hypoproteinemia (HP:0003075) | 2.35476001 |
| 39 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.34587942 |
| 40 | Increased intramyocellular lipid droplets (HP:0012240) | 2.33566085 |
| 41 | Abnormality of the renal cortex (HP:0011035) | 2.33017472 |
| 42 | True hermaphroditism (HP:0010459) | 2.33015542 |
| 43 | IgG deficiency (HP:0004315) | 2.31032253 |
| 44 | Abnormality of the pons (HP:0007361) | 2.30510445 |
| 45 | Lipid accumulation in hepatocytes (HP:0006561) | 2.29501257 |
| 46 | Optic disc pallor (HP:0000543) | 2.29308697 |
| 47 | Cystic liver disease (HP:0006706) | 2.28708578 |
| 48 | Renal Fanconi syndrome (HP:0001994) | 2.28703048 |
| 49 | Exertional dyspnea (HP:0002875) | 2.28432627 |
| 50 | Stomach cancer (HP:0012126) | 2.27097360 |
| 51 | Abnormality of B cell number (HP:0010975) | 2.25841093 |
| 52 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.20879424 |
| 53 | Nephronophthisis (HP:0000090) | 2.20195012 |
| 54 | Hypoplasia of the pons (HP:0012110) | 2.20008373 |
| 55 | Increased IgM level (HP:0003496) | 2.16978709 |
| 56 | Abnormality of cochlea (HP:0000375) | 2.10342813 |
| 57 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.07533892 |
| 58 | Supernumerary spleens (HP:0009799) | 2.07346890 |
| 59 | T lymphocytopenia (HP:0005403) | 2.05735198 |
| 60 | Abnormality of magnesium homeostasis (HP:0004921) | 2.05418548 |
| 61 | Attenuation of retinal blood vessels (HP:0007843) | 2.05104914 |
| 62 | Increased serum lactate (HP:0002151) | 2.03946571 |
| 63 | Abnormality of the renal collecting system (HP:0004742) | 2.03441978 |
| 64 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.01986146 |
| 65 | Constricted visual fields (HP:0001133) | 2.00764993 |
| 66 | Abnormality of the renal medulla (HP:0100957) | 1.99718929 |
| 67 | Macrocytic anemia (HP:0001972) | 1.95805134 |
| 68 | Pancytopenia (HP:0001876) | 1.94666336 |
| 69 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.90376453 |
| 70 | Chronic hepatic failure (HP:0100626) | 1.89821084 |
| 71 | Retinal dysplasia (HP:0007973) | 1.89292330 |
| 72 | Abnormal number of erythroid precursors (HP:0012131) | 1.88981807 |
| 73 | Abnormality of eosinophils (HP:0001879) | 1.88934492 |
| 74 | Abnormality of urine glucose concentration (HP:0011016) | 1.88149608 |
| 75 | Glycosuria (HP:0003076) | 1.88149608 |
| 76 | Autoimmune hemolytic anemia (HP:0001890) | 1.87869502 |
| 77 | Respiratory failure (HP:0002878) | 1.86407089 |
| 78 | Stenosis of the external auditory canal (HP:0000402) | 1.85868688 |
| 79 | Lactic acidosis (HP:0003128) | 1.85518367 |
| 80 | Carpal bone hypoplasia (HP:0001498) | 1.85501859 |
| 81 | Sclerocornea (HP:0000647) | 1.85007119 |
| 82 | Cerebral edema (HP:0002181) | 1.83993415 |
| 83 | Lissencephaly (HP:0001339) | 1.83341902 |
| 84 | Hypoplasia of the radius (HP:0002984) | 1.83159949 |
| 85 | Septo-optic dysplasia (HP:0100842) | 1.81873051 |
| 86 | Severe combined immunodeficiency (HP:0004430) | 1.81824026 |
| 87 | Methylmalonic acidemia (HP:0002912) | 1.79175475 |
| 88 | Absent septum pellucidum (HP:0001331) | 1.78840581 |
| 89 | Increased muscle lipid content (HP:0009058) | 1.78789200 |
| 90 | Synostosis of carpal bones (HP:0005048) | 1.78405142 |
| 91 | Abolished electroretinogram (ERG) (HP:0000550) | 1.77924694 |
| 92 | CNS demyelination (HP:0007305) | 1.76879202 |
| 93 | Congenital, generalized hypertrichosis (HP:0004540) | 1.76612063 |
| 94 | Hypomagnesemia (HP:0002917) | 1.76543794 |
| 95 | Asplenia (HP:0001746) | 1.74934114 |
| 96 | Slender long bone (HP:0003100) | 1.73599934 |
| 97 | Stomatitis (HP:0010280) | 1.72445369 |
| 98 | Abnormal ciliary motility (HP:0012262) | 1.71430782 |
| 99 | Genu varum (HP:0002970) | 1.70530075 |
| 100 | Type 2 muscle fiber atrophy (HP:0003554) | 1.69506486 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NME1 | 3.17129848 |
| 2 | KDR | 3.13809931 |
| 3 | WNK4 | 3.08358042 |
| 4 | TXK | 2.89279169 |
| 5 | PINK1 | 2.88784114 |
| 6 | BUB1 | 2.82628407 |
| 7 | BMPR1B | 2.77530117 |
| 8 | ACVR1B | 2.67620990 |
| 9 | VRK2 | 2.56863304 |
| 10 | TESK2 | 2.56369022 |
| 11 | ADRBK2 | 2.52399765 |
| 12 | DAPK2 | 2.46906207 |
| 13 | ZAK | 2.34611946 |
| 14 | CAMKK1 | 2.25916638 |
| 15 | CAMKK2 | 2.07987069 |
| 16 | GRK1 | 1.88912828 |
| 17 | TLK1 | 1.68404416 |
| 18 | MUSK | 1.66741673 |
| 19 | SRPK1 | 1.59690760 |
| 20 | CDC7 | 1.46319203 |
| 21 | MAP3K11 | 1.28791165 |
| 22 | MAP3K12 | 1.27741241 |
| 23 | STK16 | 1.26383945 |
| 24 | PAK6 | 1.15036930 |
| 25 | WNK3 | 1.14669429 |
| 26 | BRSK2 | 1.14352930 |
| 27 | DYRK2 | 1.13399538 |
| 28 | PLK4 | 1.12498580 |
| 29 | STK39 | 1.10041047 |
| 30 | PAK3 | 1.09609044 |
| 31 | FRK | 1.08613097 |
| 32 | TAOK3 | 1.07300297 |
| 33 | INSRR | 1.07184707 |
| 34 | BCKDK | 1.03627302 |
| 35 | CASK | 1.00987645 |
| 36 | VRK1 | 1.00963164 |
| 37 | PBK | 0.99121058 |
| 38 | AURKA | 0.98418714 |
| 39 | OXSR1 | 0.96586754 |
| 40 | PASK | 0.92441724 |
| 41 | PLK1 | 0.91714515 |
| 42 | GRK7 | 0.91500429 |
| 43 | PDK2 | 0.87676498 |
| 44 | CDK19 | 0.85576612 |
| 45 | ITK | 0.82737629 |
| 46 | BRSK1 | 0.78386702 |
| 47 | CAMK1 | 0.77287908 |
| 48 | ADRBK1 | 0.76906668 |
| 49 | MAPK13 | 0.75901517 |
| 50 | MAP4K2 | 0.73796620 |
| 51 | CHEK2 | 0.69064717 |
| 52 | WNK1 | 0.68537974 |
| 53 | ATR | 0.66303702 |
| 54 | CAMK2A | 0.65036108 |
| 55 | AURKB | 0.63839549 |
| 56 | LIMK1 | 0.63835251 |
| 57 | EPHB2 | 0.62257741 |
| 58 | PRKCQ | 0.58612623 |
| 59 | MAP2K6 | 0.57702626 |
| 60 | NUAK1 | 0.57328965 |
| 61 | TGFBR1 | 0.57024955 |
| 62 | PRKACA | 0.56395341 |
| 63 | CSNK2A1 | 0.56008037 |
| 64 | SYK | 0.55784000 |
| 65 | PIM1 | 0.55209340 |
| 66 | PHKG2 | 0.54497470 |
| 67 | PHKG1 | 0.54497470 |
| 68 | STK38L | 0.54125457 |
| 69 | CSNK1G2 | 0.53415002 |
| 70 | NEK2 | 0.52941556 |
| 71 | NTRK2 | 0.52689238 |
| 72 | PRKCI | 0.52049418 |
| 73 | AKT2 | 0.51946363 |
| 74 | CSNK1A1 | 0.51652328 |
| 75 | LCK | 0.51376888 |
| 76 | IKBKB | 0.51298540 |
| 77 | PRKCG | 0.50225089 |
| 78 | CSNK1G3 | 0.48797300 |
| 79 | LYN | 0.48531034 |
| 80 | MAP4K1 | 0.46765042 |
| 81 | PLK3 | 0.46519279 |
| 82 | TIE1 | 0.45856413 |
| 83 | BMX | 0.44930806 |
| 84 | CSNK2A2 | 0.44162659 |
| 85 | LRRK2 | 0.43395641 |
| 86 | PRKCA | 0.42847078 |
| 87 | PKN1 | 0.42217870 |
| 88 | FES | 0.41686679 |
| 89 | TEC | 0.41477876 |
| 90 | STK4 | 0.37741417 |
| 91 | TESK1 | 0.35955944 |
| 92 | EIF2AK3 | 0.35732013 |
| 93 | PRKCH | 0.35627438 |
| 94 | MAP2K7 | 0.34971118 |
| 95 | PRKCE | 0.34191212 |
| 96 | OBSCN | 0.33612261 |
| 97 | MAP3K4 | 0.33240799 |
| 98 | MARK3 | 0.33137741 |
| 99 | IKBKE | 0.33020509 |
| 100 | CSK | 0.32074668 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.44188996 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.06697419 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.51381384 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.46870771 |
| 5 | Homologous recombination_Homo sapiens_hsa03440 | 3.02436394 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.90827357 |
| 7 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.54509656 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.45782976 |
| 9 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.31807548 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.27302696 |
| 11 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.21850908 |
| 12 | RNA polymerase_Homo sapiens_hsa03020 | 2.21244680 |
| 13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.12762722 |
| 14 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.88977828 |
| 15 | Basal transcription factors_Homo sapiens_hsa03022 | 1.87693434 |
| 16 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.77192046 |
| 17 | Asthma_Homo sapiens_hsa05310 | 1.65727478 |
| 18 | DNA replication_Homo sapiens_hsa03030 | 1.64232150 |
| 19 | Allograft rejection_Homo sapiens_hsa05330 | 1.61216766 |
| 20 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.60511375 |
| 21 | Mismatch repair_Homo sapiens_hsa03430 | 1.54865789 |
| 22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.54781376 |
| 23 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.52557896 |
| 24 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.50949144 |
| 25 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.40414312 |
| 26 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.38510564 |
| 27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.35618058 |
| 28 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.35143228 |
| 29 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.29325570 |
| 30 | RNA degradation_Homo sapiens_hsa03018 | 1.26022798 |
| 31 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.25613488 |
| 32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.25328343 |
| 33 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.21943997 |
| 34 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.18311033 |
| 35 | Phototransduction_Homo sapiens_hsa04744 | 1.18179235 |
| 36 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.16504584 |
| 37 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.13526510 |
| 38 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.12897169 |
| 39 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.12870199 |
| 40 | Base excision repair_Homo sapiens_hsa03410 | 1.06699118 |
| 41 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.99700967 |
| 42 | RNA transport_Homo sapiens_hsa03013 | 0.98945612 |
| 43 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.91073688 |
| 44 | Nicotine addiction_Homo sapiens_hsa05033 | 0.90076871 |
| 45 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.80307661 |
| 46 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.78582639 |
| 47 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.76754435 |
| 48 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.76362475 |
| 49 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.75239310 |
| 50 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.73274017 |
| 51 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.72517439 |
| 52 | ABC transporters_Homo sapiens_hsa02010 | 0.71944168 |
| 53 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.71837382 |
| 54 | Spliceosome_Homo sapiens_hsa03040 | 0.71183099 |
| 55 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.70781380 |
| 56 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.70571364 |
| 57 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.68907781 |
| 58 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.67277864 |
| 59 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.67273081 |
| 60 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.65446498 |
| 61 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.65051178 |
| 62 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.64478379 |
| 63 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.63782917 |
| 64 | Purine metabolism_Homo sapiens_hsa00230 | 0.63674784 |
| 65 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.61733121 |
| 66 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.59775515 |
| 67 | Taste transduction_Homo sapiens_hsa04742 | 0.57513494 |
| 68 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.55071947 |
| 69 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.52343910 |
| 70 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.51307426 |
| 71 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.50920431 |
| 72 | Cell cycle_Homo sapiens_hsa04110 | 0.50837257 |
| 73 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.50628234 |
| 74 | Metabolic pathways_Homo sapiens_hsa01100 | 0.50138838 |
| 75 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.50068808 |
| 76 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.48878058 |
| 77 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.48852533 |
| 78 | Olfactory transduction_Homo sapiens_hsa04740 | 0.48404694 |
| 79 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.43967359 |
| 80 | Retinol metabolism_Homo sapiens_hsa00830 | 0.42580241 |
| 81 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.42450147 |
| 82 | Morphine addiction_Homo sapiens_hsa05032 | 0.42186226 |
| 83 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.41258134 |
| 84 | Peroxisome_Homo sapiens_hsa04146 | 0.38631222 |
| 85 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.37556145 |
| 86 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.34523844 |
| 87 | Mineral absorption_Homo sapiens_hsa04978 | 0.34060206 |
| 88 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.33738737 |
| 89 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.33565284 |
| 90 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.29400783 |
| 91 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.28246090 |
| 92 | Insulin secretion_Homo sapiens_hsa04911 | 0.27939430 |
| 93 | GABAergic synapse_Homo sapiens_hsa04727 | 0.26911083 |
| 94 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.25578825 |
| 95 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.25250610 |
| 96 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.25190466 |
| 97 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.23398428 |
| 98 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.21050917 |
| 99 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.20603887 |
| 100 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.20426120 |

