TCERG1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.19505529
2DNA unwinding involved in DNA replication (GO:0006268)5.17963757
3nuclear pore organization (GO:0006999)5.00572939
4mitotic sister chromatid cohesion (GO:0007064)4.37519326
5protein localization to kinetochore (GO:0034501)4.30560582
6DNA replication initiation (GO:0006270)4.19434610
7pore complex assembly (GO:0046931)3.97608012
8DNA strand elongation involved in DNA replication (GO:0006271)3.97308466
9kinetochore organization (GO:0051383)3.95713668
10mitotic nuclear envelope disassembly (GO:0007077)3.93205849
11replication fork processing (GO:0031297)3.87989053
12DNA strand elongation (GO:0022616)3.79950961
13pre-miRNA processing (GO:0031054)3.72072431
14IMP biosynthetic process (GO:0006188)3.70181583
15mitotic metaphase plate congression (GO:0007080)3.66819385
16regulation of sister chromatid cohesion (GO:0007063)3.65741435
17nuclear envelope disassembly (GO:0051081)3.65563428
18membrane disassembly (GO:0030397)3.65563428
19protein localization to chromosome, centromeric region (GO:0071459)3.64323853
20sister chromatid segregation (GO:0000819)3.64289982
21mitotic sister chromatid segregation (GO:0000070)3.64003611
22DNA duplex unwinding (GO:0032508)3.63004805
23telomere maintenance via semi-conservative replication (GO:0032201)3.61898263
24DNA geometric change (GO:0032392)3.61082684
25regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.57538323
26DNA replication checkpoint (GO:0000076)3.49987092
27DNA ligation (GO:0006266)3.49790115
28negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.46485233
29non-recombinational repair (GO:0000726)3.45765737
30double-strand break repair via nonhomologous end joining (GO:0006303)3.45765737
31heterochromatin organization (GO:0070828)3.45701764
32regulation of histone H3-K9 methylation (GO:0051570)3.45567439
33mitotic recombination (GO:0006312)3.45271099
34metaphase plate congression (GO:0051310)3.45131875
35mitotic chromosome condensation (GO:0007076)3.42611511
36kinetochore assembly (GO:0051382)3.38724842
37telomere maintenance via recombination (GO:0000722)3.38405046
38regulation of spindle organization (GO:0090224)3.37996897
39DNA replication-dependent nucleosome assembly (GO:0006335)3.34937544
40DNA replication-dependent nucleosome organization (GO:0034723)3.34937544
41dosage compensation (GO:0007549)3.32010451
42negative regulation of DNA recombination (GO:0045910)3.31170200
43negative regulation of histone methylation (GO:0031061)3.30808985
44DNA double-strand break processing (GO:0000729)3.27664022
45regulation of RNA export from nucleus (GO:0046831)3.26425077
46IMP metabolic process (GO:0046040)3.25960798
47positive regulation of chromosome segregation (GO:0051984)3.25656257
48regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.25186501
49regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.25048152
50regulation of mitotic spindle checkpoint (GO:1903504)3.25048152
51nucleobase biosynthetic process (GO:0046112)3.23686508
52DNA replication-independent nucleosome organization (GO:0034724)3.22875222
53DNA replication-independent nucleosome assembly (GO:0006336)3.22875222
54negative regulation of RNA splicing (GO:0033119)3.22232649
55chromatin remodeling at centromere (GO:0031055)3.21824532
56establishment of integrated proviral latency (GO:0075713)3.20205783
57CENP-A containing nucleosome assembly (GO:0034080)3.17846355
58meiotic chromosome segregation (GO:0045132)3.16655636
59histone H2A acetylation (GO:0043968)3.15488769
60attachment of spindle microtubules to kinetochore (GO:0008608)3.14904970
61establishment of chromosome localization (GO:0051303)3.14830047
62maturation of SSU-rRNA (GO:0030490)3.13978144
63telomere maintenance via telomere lengthening (GO:0010833)3.13319030
64formation of translation preinitiation complex (GO:0001731)3.13074528
65microtubule depolymerization (GO:0007019)3.12359385
66DNA topological change (GO:0006265)3.10973971
67regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.10586376
68negative regulation of mRNA processing (GO:0050686)3.08626536
69nucleotide-excision repair, DNA gap filling (GO:0006297)3.08588179
70regulation of DNA endoreduplication (GO:0032875)3.08310546
71regulation of centrosome duplication (GO:0010824)3.07376390
72regulation of mitotic spindle organization (GO:0060236)3.06802870
73translesion synthesis (GO:0019985)3.06278206
74regulation of mitotic sister chromatid separation (GO:0010965)3.05444100
75negative regulation of mRNA metabolic process (GO:1903312)3.05118342
76regulation of chromosome segregation (GO:0051983)3.04256144
77somatic hypermutation of immunoglobulin genes (GO:0016446)3.03361447
78somatic diversification of immune receptors via somatic mutation (GO:0002566)3.03361447
79regulation of nuclear cell cycle DNA replication (GO:0033262)3.02796092
80regulation of centrosome cycle (GO:0046605)3.01897752
81spindle checkpoint (GO:0031577)3.01844802
82alternative mRNA splicing, via spliceosome (GO:0000380)3.01442856
83regulation of helicase activity (GO:0051095)3.01084251
84protein localization to chromosome (GO:0034502)3.00808442
85DNA conformation change (GO:0071103)3.00749693
86chromatin assembly or disassembly (GO:0006333)3.00727112
87resolution of meiotic recombination intermediates (GO:0000712)2.99932451
88RNA splicing, via transesterification reactions (GO:0000375)2.98426377
89termination of RNA polymerase II transcription (GO:0006369)2.97929837
90centriole replication (GO:0007099)2.96658390
91mRNA splicing, via spliceosome (GO:0000398)2.95690098
92RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.95690098
93positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.94896013
94positive regulation of mitotic sister chromatid separation (GO:1901970)2.94896013
95positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.94896013
96sister chromatid cohesion (GO:0007062)2.94758953
97regulation of centriole replication (GO:0046599)2.93019181
98negative regulation of chromosome segregation (GO:0051985)2.92900087
99histone exchange (GO:0043486)2.92553929
100spindle assembly checkpoint (GO:0071173)2.92545722
101regulation of mitotic metaphase/anaphase transition (GO:0030071)2.91583086
102mitotic spindle checkpoint (GO:0071174)2.90002921
103ATP-dependent chromatin remodeling (GO:0043044)2.89563273
104negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.88959191
105negative regulation of sister chromatid segregation (GO:0033046)2.88959191
106negative regulation of mitotic sister chromatid separation (GO:2000816)2.88959191
107negative regulation of mitotic sister chromatid segregation (GO:0033048)2.88959191
108negative regulation of DNA-dependent DNA replication (GO:2000104)2.88266372
109ribosome assembly (GO:0042255)2.86630260
110mitotic spindle assembly checkpoint (GO:0007094)2.86155981
111postreplication repair (GO:0006301)2.85878711
112regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.84979929
113purine nucleobase biosynthetic process (GO:0009113)2.84320854
114mRNA transport (GO:0051028)2.84057764
115nuclear envelope organization (GO:0006998)2.82033772
116mRNA splice site selection (GO:0006376)2.81806207
117negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.80491102
118maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.80226465
119chromosome segregation (GO:0007059)2.79932614
120regulation of mitotic sister chromatid segregation (GO:0033047)2.79927670
121regulation of sister chromatid segregation (GO:0033045)2.79927670
122positive regulation of histone H3-K4 methylation (GO:0051571)2.79057025
123DNA damage response, detection of DNA damage (GO:0042769)2.77174739
124mitotic G2/M transition checkpoint (GO:0044818)2.74198945
125regulation of mRNA splicing, via spliceosome (GO:0048024)2.73790291

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.44920322
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.55342169
3* MYC_18555785_ChIP-Seq_MESCs_Mouse4.07403812
4* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.52087751
5MYC_19079543_ChIP-ChIP_MESCs_Mouse2.99590592
6* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.85945019
7* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.82338020
8* EGR1_19374776_ChIP-ChIP_THP-1_Human2.79149900
9* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.67159074
10E2F1_21310950_ChIP-Seq_MCF-7_Human2.52320512
11TP63_19390658_ChIP-ChIP_HaCaT_Human2.45069959
12AR_21909140_ChIP-Seq_LNCAP_Human2.37988523
13MYC_22102868_ChIP-Seq_BL_Human2.25049983
14NELFA_20434984_ChIP-Seq_ESCs_Mouse2.23430301
15* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.22711301
16FUS_26573619_Chip-Seq_HEK293_Human2.19541958
17EST1_17652178_ChIP-ChIP_JURKAT_Human2.16288126
18XRN2_22483619_ChIP-Seq_HELA_Human2.10929882
19MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.08539851
20MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.05941695
21E2F7_22180533_ChIP-Seq_HELA_Human11.2578954
22SALL1_21062744_ChIP-ChIP_HESCs_Human1.99840882
23MYCN_18555785_ChIP-Seq_MESCs_Mouse1.97351399
24ETS1_20019798_ChIP-Seq_JURKAT_Human1.95845810
25KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.89912270
26* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.84941831
27CIITA_25753668_ChIP-Seq_RAJI_Human1.83776929
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.79916967
29* VDR_23849224_ChIP-Seq_CD4+_Human1.78668508
30* CREB1_15753290_ChIP-ChIP_HEK293T_Human1.78118962
31ZNF274_21170338_ChIP-Seq_K562_Hela1.77994253
32HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.77647281
33MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.76451650
34TTF2_22483619_ChIP-Seq_HELA_Human1.73301761
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.71156418
36FOXP3_21729870_ChIP-Seq_TREG_Human1.67470734
37RBPJ_22232070_ChIP-Seq_NCS_Mouse1.67231232
38PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67023887
39GABP_17652178_ChIP-ChIP_JURKAT_Human1.59570696
40POU3F2_20337985_ChIP-ChIP_501MEL_Human1.59427813
41IGF1R_20145208_ChIP-Seq_DFB_Human1.57836198
42GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.56176040
43ELK1_19687146_ChIP-ChIP_HELA_Human1.54059650
44JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.51729506
45HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.51184303
46KDM5A_27292631_Chip-Seq_BREAST_Human1.49237571
47POU5F1_16153702_ChIP-ChIP_HESCs_Human1.47199811
48NANOG_18555785_ChIP-Seq_MESCs_Mouse1.42299678
49TAF15_26573619_Chip-Seq_HEK293_Human1.41754164
50ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.41638674
51* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.41466223
52THAP11_20581084_ChIP-Seq_MESCs_Mouse1.41083593
53SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.40609055
54DCP1A_22483619_ChIP-Seq_HELA_Human1.40475070
55GABP_19822575_ChIP-Seq_HepG2_Human1.39008617
56* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.38145956
57* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.36096815
58TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.32181049
59FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.29582264
60VDR_22108803_ChIP-Seq_LS180_Human1.24552260
61SOX2_18555785_ChIP-Seq_MESCs_Mouse1.24154875
62NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.23717562
63* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.23349418
64* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.22017665
65ELF1_17652178_ChIP-ChIP_JURKAT_Human1.20097171
66ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.19497908
67HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.17794429
68E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.17723912
69PADI4_21655091_ChIP-ChIP_MCF-7_Human1.17588494
70* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.17339750
71SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.12189089
72CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.12074480
73VDR_21846776_ChIP-Seq_THP-1_Human1.11215412
74ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.10669717
75SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.09998209
76NOTCH1_21737748_ChIP-Seq_TLL_Human1.09996807
77* NANOG_16153702_ChIP-ChIP_HESCs_Human1.09819694
78NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.09477822
79ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.09089794
80KLF4_18555785_ChIP-Seq_MESCs_Mouse1.07775423
81POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.07348343
82KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.06974280
83TFEB_21752829_ChIP-Seq_HELA_Human1.06680074
84CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.06132850
85HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.05681339
86DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.04108902
87NANOG_21062744_ChIP-ChIP_HESCs_Human1.02510318
88P300_19829295_ChIP-Seq_ESCs_Human1.01554773
89POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.00617659
90DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.00056638
91SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.99466579
92IRF1_19129219_ChIP-ChIP_H3396_Human0.98357689
93ZFP57_27257070_Chip-Seq_ESCs_Mouse0.98054136
94KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.97069042
95KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.97069042
96KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.97069042
97CTBP2_25329375_ChIP-Seq_LNCAP_Human0.95921646
98PKCTHETA_26484144_Chip-Seq_BREAST_Human0.95670213
99SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.93833792
100GBX2_23144817_ChIP-Seq_PC3_Human0.92022074
101* SOX9_26525672_Chip-Seq_HEART_Mouse0.91818339
102FLI1_27457419_Chip-Seq_LIVER_Mouse0.89872737
103CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.89541993
104* MYC_18940864_ChIP-ChIP_HL60_Human0.89136072
105* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.88701148
106E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.88608437
107CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.88305243
108CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.88112303
109GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.87098600
110SRF_21415370_ChIP-Seq_HL-1_Mouse0.86873657
111NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.86684397
112FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.85888817
113CTBP1_25329375_ChIP-Seq_LNCAP_Human0.85391405
114YY1_21170310_ChIP-Seq_MESCs_Mouse0.83838227
115CHD1_26751641_Chip-Seq_LNCaP_Human0.82738998
116PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.82165539
117STAT3_1855785_ChIP-Seq_MESCs_Mouse0.82009186
118SOX2_16153702_ChIP-ChIP_HESCs_Human0.81982420
119TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.81953279
120TCF3_18692474_ChIP-Seq_MEFs_Mouse0.81675197
121* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.81479910
122ESR1_15608294_ChIP-ChIP_MCF-7_Human0.80029770
123ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.80025832
124MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.79718058
125MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.78709639
126EWS_26573619_Chip-Seq_HEK293_Human0.78511783
127TCF3_18692474_ChIP-Seq_MESCs_Mouse0.77429115
128TCF7_22412390_ChIP-Seq_EML_Mouse0.76881194
129TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.76667087
130POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.76667087
131SPI1_23547873_ChIP-Seq_NB4_Human0.75900497
132PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.75193928
133RNF2_27304074_Chip-Seq_NSC_Mouse0.74231996
134WT1_19549856_ChIP-ChIP_CCG9911_Human0.73570842
135GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.73087578

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.44273007
2MP0010094_abnormal_chromosome_stability4.21740552
3MP0003111_abnormal_nucleus_morphology3.93719871
4MP0003693_abnormal_embryo_hatching3.92487125
5MP0004957_abnormal_blastocyst_morpholog3.59470992
6MP0003077_abnormal_cell_cycle3.47253973
7MP0008058_abnormal_DNA_repair2.86967104
8MP0003123_paternal_imprinting2.64803254
9MP0008877_abnormal_DNA_methylation2.61758049
10MP0002396_abnormal_hematopoietic_system2.60256109
11MP0008007_abnormal_cellular_replicative2.45013674
12MP0003121_genomic_imprinting2.41760331
13MP0010352_gastrointestinal_tract_polyps2.36772523
14MP0001730_embryonic_growth_arrest2.25690892
15MP0005076_abnormal_cell_differentiation2.24536555
16MP0008932_abnormal_embryonic_tissue2.21974988
17MP0000350_abnormal_cell_proliferation2.16090396
18MP0010307_abnormal_tumor_latency1.96664627
19MP0003890_abnormal_embryonic-extraembry1.87418319
20MP0004808_abnormal_hematopoietic_stem1.86821738
21MP0001672_abnormal_embryogenesis/_devel1.81585782
22MP0005380_embryogenesis_phenotype1.81585782
23MP0002084_abnormal_developmental_patter1.79853234
24MP0001697_abnormal_embryo_size1.79462516
25MP0009697_abnormal_copulation1.76598982
26MP0002085_abnormal_embryonic_tissue1.72389681
27MP0000537_abnormal_urethra_morphology1.70030898
28MP0003984_embryonic_growth_retardation1.66097830
29MP0004197_abnormal_fetal_growth/weight/1.63547828
30MP0003567_abnormal_fetal_cardiomyocyte1.62846994
31MP0002088_abnormal_embryonic_growth/wei1.62495531
32MP0003718_maternal_effect1.61207550
33MP0008995_early_reproductive_senescence1.55211794
34MP0003787_abnormal_imprinting1.54964323
35MP0002086_abnormal_extraembryonic_tissu1.53113986
36MP0001529_abnormal_vocalization1.48169908
37MP0003786_premature_aging1.46622276
38MP0002080_prenatal_lethality1.46108190
39MP0010030_abnormal_orbit_morphology1.44552357
40MP0006292_abnormal_olfactory_placode1.41381666
41MP0000778_abnormal_nervous_system1.38494963
42MP0005394_taste/olfaction_phenotype1.37333939
43MP0005499_abnormal_olfactory_system1.37333939
44MP0001293_anophthalmia1.36229366
45MP0002233_abnormal_nose_morphology1.35394381
46MP0002009_preneoplasia1.33108064
47MP0009053_abnormal_anal_canal1.30891057
48MP0002234_abnormal_pharynx_morphology1.28538863
49MP0000490_abnormal_crypts_of1.28360058
50MP0006072_abnormal_retinal_apoptosis1.26832185
51MP0000313_abnormal_cell_death1.26568288
52MP0003937_abnormal_limbs/digits/tail_de1.25791617
53MP0003136_yellow_coat_color1.22530549
54MP0004147_increased_porphyrin_level1.21319279
55MP0003119_abnormal_digestive_system1.19547295
56MP0001188_hyperpigmentation1.18902062
57MP0002751_abnormal_autonomic_nervous1.18341404
58MP0000631_abnormal_neuroendocrine_gland1.18258654
59MP0003880_abnormal_central_pattern1.17466740
60MP0001545_abnormal_hematopoietic_system1.16074742
61MP0005397_hematopoietic_system_phenotyp1.16074742
62MP0000703_abnormal_thymus_morphology1.14868876
63MP0002019_abnormal_tumor_incidence1.12008110
64MP0003122_maternal_imprinting1.08352393
65MP0002210_abnormal_sex_determination1.08026734
66MP0003941_abnormal_skin_development1.07317931
67MP0006035_abnormal_mitochondrial_morpho1.04695940
68MP0009278_abnormal_bone_marrow1.04076110
69MP0001346_abnormal_lacrimal_gland1.03999406
70MP0000428_abnormal_craniofacial_morphol1.02323983
71MP0001299_abnormal_eye_distance/1.01274061
72MP0006054_spinal_hemorrhage1.00805447
73MP0009672_abnormal_birth_weight0.98220643
74MP0005187_abnormal_penis_morphology0.96365173
75MP0009703_decreased_birth_body0.95765846
76MP0003763_abnormal_thymus_physiology0.94789133
77MP0003861_abnormal_nervous_system0.92757427
78MP0000432_abnormal_head_morphology0.92479388
79MP0001145_abnormal_male_reproductive0.92205885
80MP0002398_abnormal_bone_marrow0.91548790
81MP0003935_abnormal_craniofacial_develop0.91503381
82MP0001984_abnormal_olfaction0.91361590
83MP0000566_synostosis0.91228908
84MP0000647_abnormal_sebaceous_gland0.89316341
85MP0001286_abnormal_eye_development0.88840254
86MP0004133_heterotaxia0.88217005
87MP0003755_abnormal_palate_morphology0.87151341
88MP0001915_intracranial_hemorrhage0.86801554
89MP0000733_abnormal_muscle_development0.86514529
90MP0002111_abnormal_tail_morphology0.86372424
91MP0005391_vision/eye_phenotype0.85749995
92MP0002925_abnormal_cardiovascular_devel0.84988678
93MP0003698_abnormal_male_reproductive0.84438408
94MP0000569_abnormal_digit_pigmentation0.84396240
95MP0002938_white_spotting0.82143348
96MP0000049_abnormal_middle_ear0.80784117
97MP0002184_abnormal_innervation0.80585751
98MP0003115_abnormal_respiratory_system0.79911587
99MP0002722_abnormal_immune_system0.79306092
100MP0003315_abnormal_perineum_morphology0.77842649
101MP0005645_abnormal_hypothalamus_physiol0.77223432
102MP0002092_abnormal_eye_morphology0.77038276
103MP0000653_abnormal_sex_gland0.77008209
104MP0001929_abnormal_gametogenesis0.76862637
105MP0002152_abnormal_brain_morphology0.75189294
106MP0000955_abnormal_spinal_cord0.74346682
107MP0001177_atelectasis0.73343297
108MP0000358_abnormal_cell_content/0.73098311
109MP0005646_abnormal_pituitary_gland0.72779176
110MP0002697_abnormal_eye_size0.72389083
111MP0002114_abnormal_axial_skeleton0.71449698
112MP0005253_abnormal_eye_physiology0.70144978
113MP0002116_abnormal_craniofacial_bone0.69057884
114MP0005384_cellular_phenotype0.68735202
115MP0003385_abnormal_body_wall0.67705441
116MP0005621_abnormal_cell_physiology0.67672693
117MP0000383_abnormal_hair_follicle0.66976765
118MP0000372_irregular_coat_pigmentation0.66796859
119MP0008789_abnormal_olfactory_epithelium0.66627045
120MP0003938_abnormal_ear_development0.66223546
121MP0000689_abnormal_spleen_morphology0.66198043
122MP0002736_abnormal_nociception_after0.65853888
123MP0003942_abnormal_urinary_system0.65673179
124MP0001849_ear_inflammation0.64326524
125MP0002932_abnormal_joint_morphology0.61935092
126MP0001119_abnormal_female_reproductive0.61735890
127MP0009333_abnormal_splenocyte_physiolog0.60438665
128MP0008770_decreased_survivor_rate0.59950808
129MP0002653_abnormal_ependyma_morphology0.59890839
130MP0002081_perinatal_lethality0.59505906
131MP0002160_abnormal_reproductive_system0.59406684
132MP0002075_abnormal_coat/hair_pigmentati0.59389773
133MP0002102_abnormal_ear_morphology0.58903962
134MP0000266_abnormal_heart_morphology0.58715382
135MP0003943_abnormal_hepatobiliary_system0.57598245
136MP0002429_abnormal_blood_cell0.57404862

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)3.77112631
2Volvulus (HP:0002580)3.66855174
3Ependymoma (HP:0002888)3.46685255
4Medulloblastoma (HP:0002885)3.45835252
5Chromosomal breakage induced by crosslinking agents (HP:0003221)3.43148939
6Birth length less than 3rd percentile (HP:0003561)3.42104562
7Increased nuchal translucency (HP:0010880)3.09852412
8Colon cancer (HP:0003003)3.06637984
9Abnormality of chromosome stability (HP:0003220)2.92747320
10Proximal placement of thumb (HP:0009623)2.90304147
11Abnormality of the labia minora (HP:0012880)2.81049703
12Deviation of the thumb (HP:0009603)2.80835876
13Abnormality of the fingertips (HP:0001211)2.72074839
14Meckel diverticulum (HP:0002245)2.69852140
15Abnormality of the astrocytes (HP:0100707)2.65897902
16Astrocytoma (HP:0009592)2.65897902
17Selective tooth agenesis (HP:0001592)2.64410555
18Ectopic kidney (HP:0000086)2.60085939
19Patellar aplasia (HP:0006443)2.59285376
20Abnormality of the ileum (HP:0001549)2.58063589
21Neoplasm of the oral cavity (HP:0100649)2.56654543
22Reticulocytopenia (HP:0001896)2.53777404
23Abnormal number of incisors (HP:0011064)2.49750805
24Abnormality of the preputium (HP:0100587)2.48894707
25Aplasia/Hypoplasia of the uvula (HP:0010293)2.46573919
26Cortical dysplasia (HP:0002539)2.43749793
27Myelodysplasia (HP:0002863)2.41815933
28Aplasia/Hypoplasia of the patella (HP:0006498)2.39081442
29Absent radius (HP:0003974)2.37633861
30Duodenal stenosis (HP:0100867)2.36004444
31Small intestinal stenosis (HP:0012848)2.36004444
32Agnosia (HP:0010524)2.35875977
33Glioma (HP:0009733)2.35433369
34Aplasia/Hypoplasia of the sternum (HP:0006714)2.35353910
35Rhabdomyosarcoma (HP:0002859)2.35187946
36Long eyelashes (HP:0000527)2.33210196
37Short 4th metacarpal (HP:0010044)2.33054506
38Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.33054506
39Nephroblastoma (Wilms tumor) (HP:0002667)2.31033570
40Facial hemangioma (HP:0000329)2.25854526
41Supernumerary spleens (HP:0009799)2.24886712
42Aplasia involving forearm bones (HP:0009822)2.20745571
43Absent forearm bone (HP:0003953)2.20745571
44Prominent nose (HP:0000448)2.18599117
45Embryonal renal neoplasm (HP:0011794)2.16833619
46High anterior hairline (HP:0009890)2.12769739
47Neoplasm of striated muscle (HP:0009728)2.12106553
48Abnormality of the carotid arteries (HP:0005344)2.11009617
49Breast hypoplasia (HP:0003187)2.10756436
50Basal cell carcinoma (HP:0002671)2.08696009
51Absent thumb (HP:0009777)2.07815315
52Atresia of the external auditory canal (HP:0000413)2.07320144
53Hepatoblastoma (HP:0002884)2.06505536
54Triphalangeal thumb (HP:0001199)2.04755848
55Abnormality of the anterior horn cell (HP:0006802)2.03927379
56Degeneration of anterior horn cells (HP:0002398)2.03927379
57Abnormal lung lobation (HP:0002101)2.03679466
58Abnormality of abdominal situs (HP:0011620)2.03574068
59Abdominal situs inversus (HP:0003363)2.03574068
60Aplastic anemia (HP:0001915)2.02186145
61Intestinal atresia (HP:0011100)2.00945972
62Renal duplication (HP:0000075)1.96563965
63Cafe-au-lait spot (HP:0000957)1.95608455
64Pancreatic fibrosis (HP:0100732)1.94633888
65Abnormality of the duodenum (HP:0002246)1.93741754
66Pancreatic cysts (HP:0001737)1.93289364
67Impulsivity (HP:0100710)1.92298615
68Supernumerary ribs (HP:0005815)1.91674935
69Abnormality of cochlea (HP:0000375)1.90791814
70Horseshoe kidney (HP:0000085)1.89983746
71Supernumerary bones of the axial skeleton (HP:0009144)1.89244903
72Sloping forehead (HP:0000340)1.88427661
73Short thumb (HP:0009778)1.87591199
74Preaxial hand polydactyly (HP:0001177)1.87336167
75Nephronophthisis (HP:0000090)1.87169555
7611 pairs of ribs (HP:0000878)1.86242817
77High pitched voice (HP:0001620)1.85462763
78Tracheoesophageal fistula (HP:0002575)1.83559389
79Oligodactyly (hands) (HP:0001180)1.83359229
80Deep philtrum (HP:0002002)1.83167533
81Abnormality of midbrain morphology (HP:0002418)1.83106905
82Molar tooth sign on MRI (HP:0002419)1.83106905
83Gastrointestinal carcinoma (HP:0002672)1.82784744
84Malignant gastrointestinal tract tumors (HP:0006749)1.82784744
85Amaurosis fugax (HP:0100576)1.81862585
86Urethral obstruction (HP:0000796)1.81788384
87Carpal bone hypoplasia (HP:0001498)1.81786357
88Broad thumb (HP:0011304)1.81429190
89Septo-optic dysplasia (HP:0100842)1.81155079
90Neoplasm of the pancreas (HP:0002894)1.81033246
91Acute lymphatic leukemia (HP:0006721)1.79712510
92True hermaphroditism (HP:0010459)1.79424031
93Acute myeloid leukemia (HP:0004808)1.79079006
94Abnormal hair whorl (HP:0010721)1.78009343
95Abnormality of the septum pellucidum (HP:0007375)1.77554054
96Abnormality of DNA repair (HP:0003254)1.76314595
97Neoplasm of the adrenal cortex (HP:0100641)1.75706091
98Pelvic girdle muscle weakness (HP:0003749)1.75677966
99Missing ribs (HP:0000921)1.75089442
100Tubulointerstitial nephritis (HP:0001970)1.74657362
101Abnormality of chromosome segregation (HP:0002916)1.74109159
102Dandy-Walker malformation (HP:0001305)1.74103712
103Broad palm (HP:0001169)1.73848620
104Long clavicles (HP:0000890)1.72591656
105Skull defect (HP:0001362)1.72339969
106Oral leukoplakia (HP:0002745)1.71389801
107Asplenia (HP:0001746)1.71219154
108Diastasis recti (HP:0001540)1.71001784
109Overlapping toe (HP:0001845)1.70734334
110Obsessive-compulsive behavior (HP:0000722)1.69840851
111Small hand (HP:0200055)1.68909628
112Skin tags (HP:0010609)1.68722612
113Low anterior hairline (HP:0000294)1.68443699
114Cutis marmorata (HP:0000965)1.68110468
115Bifid tongue (HP:0010297)1.68039291
116Hyperacusis (HP:0010780)1.67359467
117Aplasia/hypoplasia of the humerus (HP:0006507)1.66662208
118Rib fusion (HP:0000902)1.66470697
119Embryonal neoplasm (HP:0002898)1.66130041
120Sparse lateral eyebrow (HP:0005338)1.65760978
121Optic nerve coloboma (HP:0000588)1.65650198
122Preauricular skin tag (HP:0000384)1.64570759
123Abnormality of the renal collecting system (HP:0004742)1.63011965
124Choanal atresia (HP:0000453)1.62864156
125Anophthalmia (HP:0000528)1.62668184
126Esophageal atresia (HP:0002032)1.62413785
127Biliary tract neoplasm (HP:0100574)1.62375212
128Clubbing of toes (HP:0100760)1.62182348
129Bone marrow hypocellularity (HP:0005528)1.61745276
130Duplicated collecting system (HP:0000081)1.61028933
131Morphological abnormality of the inner ear (HP:0011390)1.60727363
132Broad phalanges of the hand (HP:0009768)1.60564497
133Hypoplastic pelvis (HP:0008839)1.59928870
134Absent septum pellucidum (HP:0001331)1.59701780
135Drooling (HP:0002307)1.57405722
136Astigmatism (HP:0000483)1.57051179
137Chronic hepatic failure (HP:0100626)1.56944056
138Postaxial foot polydactyly (HP:0001830)1.56524114
139Highly arched eyebrow (HP:0002553)1.55923443
140Oligodactyly (HP:0012165)1.54344702
141Abnormality of the renal medulla (HP:0100957)1.53909814
142Bilateral microphthalmos (HP:0007633)1.53485335
143Hypoplastic female external genitalia (HP:0012815)1.52802154
144Holoprosencephaly (HP:0001360)1.52335939
145Arteriovenous malformation (HP:0100026)1.52196635
146Optic nerve hypoplasia (HP:0000609)1.51725296
147Abnormality of the metopic suture (HP:0005556)1.51692016
148Lissencephaly (HP:0001339)1.51334246
149Partial agenesis of the corpus callosum (HP:0001338)1.50294054
150Microvesicular hepatic steatosis (HP:0001414)1.50021809

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.30144096
2WEE13.93653468
3CDK123.77212610
4NEK22.98073501
5SRPK12.92052734
6BUB12.81556830
7MKNK12.61740976
8TTK2.42666715
9TSSK62.24344869
10EEF2K2.13601108
11ATR2.11355689
12MKNK22.02292362
13NEK11.97629990
14ACVR1B1.97092798
15CDK71.96943806
16WNK31.94550095
17BRD41.94467242
18PLK11.85516369
19EIF2AK11.85305790
20TRIM281.85234802
21PLK31.80520771
22TNIK1.78587265
23NUAK11.77651938
24BRSK21.76739202
25PNCK1.75442583
26RPS6KB21.70754162
27CHEK11.65449667
28PLK41.62419383
29BCR1.60325167
30PASK1.58669901
31CDK41.57589503
32AURKB1.56880264
33MAP3K41.56206305
34CHEK21.53994241
35RPS6KA41.53904315
36MAP3K101.52549529
37BMPR1B1.49872873
38MAP4K21.47331847
39CASK1.40437891
40TGFBR11.36681741
41ATM1.36470872
42CDK61.35186768
43STK101.34646571
44ALK1.32046873
45MAP3K81.29681533
46SCYL21.28596323
47CDK21.19931917
48DYRK31.18342961
49VRK21.15903931
50VRK11.09521982
51PAK41.05358973
52TAF11.04352633
53BRSK11.03795196
54AKT31.03490567
55EIF2AK31.02152964
56MELK1.01885574
57NME11.00100264
58CCNB10.98507910
59CLK10.96772651
60CDK10.95598100
61FRK0.94516218
62MAPK130.93537538
63STK40.91919435
64EPHA40.88993792
65CSNK1G10.85762396
66AURKA0.84888020
67MTOR0.83325540
68STK30.80929160
69CDK30.78890147
70EPHA20.75152315
71CDK80.74348821
72MARK10.72815927
73DYRK20.72105730
74CSNK2A20.71602086
75MAP4K10.68142377
76PIM10.67356343
77CSNK1E0.66906268
78ERBB30.64638233
79NME20.63939370
80PRKDC0.61675970
81MAPK140.60293134
82CSNK1G20.60273308
83PKN20.58972746
84WNK40.58801069
85STK390.56048127
86CSNK1D0.54846163
87BTK0.53837882
88TESK20.53785986
89MINK10.52234635
90MAP2K70.50734455
91MST40.50362751
92PAK20.50117877
93CSNK2A10.48920747
94NTRK20.48862314
95ZAK0.47035734
96FGFR10.46840699
97AKT20.46696108
98GSK3B0.44578999
99CSNK1A1L0.44444871
100INSRR0.44162300
101STK38L0.44107577
102FGFR20.44050349
103CDK90.43849551
104SIK20.43486450
105PDK20.41974998
106BRAF0.40710882
107SIK30.40357289
108AKT10.40283898
109LATS20.39962948
110FLT30.39767636
111LRRK20.39193254
112LATS10.38998488
113JAK30.38080728
114MAPK10.37121558
115PBK0.36854143
116UHMK10.36583424
117STK160.35800785
118MAP2K30.34881732
119PAK10.34824793
120YES10.34554976
121RPS6KA50.34527270
122TLK10.34203254
123MAPKAPK50.34073977
124KSR10.33628975
125RPS6KB10.33479211
126CHUK0.33143599
127PRKCG0.33030027
128DYRK1A0.32508529
129PRKACB0.32340765
130CAMK1D0.31264722
131TAOK20.31256895
132CSNK1G30.30240256
133MARK30.29323385
134MAPK100.28689889
135CAMK1G0.27279558
136PLK20.26110112
137EIF2AK20.25099962

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.22619952
2Mismatch repair_Homo sapiens_hsa034303.66174066
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.27351581
4* Spliceosome_Homo sapiens_hsa030403.17960997
5RNA transport_Homo sapiens_hsa030132.98242862
6Cell cycle_Homo sapiens_hsa041102.86333370
7Base excision repair_Homo sapiens_hsa034102.66095517
8Homologous recombination_Homo sapiens_hsa034402.63276140
9Fanconi anemia pathway_Homo sapiens_hsa034602.41431071
10Nucleotide excision repair_Homo sapiens_hsa034202.34605850
11Non-homologous end-joining_Homo sapiens_hsa034502.24569696
12mRNA surveillance pathway_Homo sapiens_hsa030152.23807494
13RNA polymerase_Homo sapiens_hsa030202.23626708
14RNA degradation_Homo sapiens_hsa030182.02791293
15Protein export_Homo sapiens_hsa030602.00715765
16One carbon pool by folate_Homo sapiens_hsa006701.98560318
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.96673976
18Ribosome_Homo sapiens_hsa030101.94782612
19Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.79645028
20Basal transcription factors_Homo sapiens_hsa030221.76835661
21Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.58499660
22Steroid biosynthesis_Homo sapiens_hsa001001.55171691
23Pyrimidine metabolism_Homo sapiens_hsa002401.53532730
24p53 signaling pathway_Homo sapiens_hsa041151.51395004
25Propanoate metabolism_Homo sapiens_hsa006401.50181768
26Selenocompound metabolism_Homo sapiens_hsa004501.44591879
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.39089592
28Oocyte meiosis_Homo sapiens_hsa041141.32918127
29MicroRNAs in cancer_Homo sapiens_hsa052061.25646681
30Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.24309318
31Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.23604596
32Proteasome_Homo sapiens_hsa030501.22444666
33Epstein-Barr virus infection_Homo sapiens_hsa051691.17579946
34Herpes simplex infection_Homo sapiens_hsa051681.11445875
35Viral carcinogenesis_Homo sapiens_hsa052031.10752972
36HTLV-I infection_Homo sapiens_hsa051661.10302271
37Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.09063536
38Colorectal cancer_Homo sapiens_hsa052101.02023437
39TGF-beta signaling pathway_Homo sapiens_hsa043501.00310769
40Transcriptional misregulation in cancer_Homo sapiens_hsa052021.00112096
41Basal cell carcinoma_Homo sapiens_hsa052170.93707223
42Pyruvate metabolism_Homo sapiens_hsa006200.93642193
43Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.92595849
44Thyroid cancer_Homo sapiens_hsa052160.91938930
45Small cell lung cancer_Homo sapiens_hsa052220.90200406
46Antigen processing and presentation_Homo sapiens_hsa046120.88345446
47Hippo signaling pathway_Homo sapiens_hsa043900.88291857
48Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.86821476
49Biosynthesis of amino acids_Homo sapiens_hsa012300.85903563
50Purine metabolism_Homo sapiens_hsa002300.84718705
51Adherens junction_Homo sapiens_hsa045200.84074850
52Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.82064627
53Chronic myeloid leukemia_Homo sapiens_hsa052200.81944349
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.80613121
55Systemic lupus erythematosus_Homo sapiens_hsa053220.80101872
56Huntingtons disease_Homo sapiens_hsa050160.77660459
57Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.77611484
58Nicotine addiction_Homo sapiens_hsa050330.77463397
59Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.75767840
60Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.74665643
61Wnt signaling pathway_Homo sapiens_hsa043100.72920199
62Notch signaling pathway_Homo sapiens_hsa043300.72624591
63Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.71782024
64Primary immunodeficiency_Homo sapiens_hsa053400.71571940
65Butanoate metabolism_Homo sapiens_hsa006500.68489432
66Hedgehog signaling pathway_Homo sapiens_hsa043400.68467233
67Hepatitis B_Homo sapiens_hsa051610.67159716
682-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.67025644
69Viral myocarditis_Homo sapiens_hsa054160.66285780
70Pathways in cancer_Homo sapiens_hsa052000.65565081
71mTOR signaling pathway_Homo sapiens_hsa041500.64570798
72Parkinsons disease_Homo sapiens_hsa050120.64383554
73Phototransduction_Homo sapiens_hsa047440.63610236
74Prostate cancer_Homo sapiens_hsa052150.61915424
75Thyroid hormone signaling pathway_Homo sapiens_hsa049190.59852355
76Carbon metabolism_Homo sapiens_hsa012000.59767794
77Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.59687587
78Measles_Homo sapiens_hsa051620.59372865
79Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.59216873
80Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.59107327
81Non-small cell lung cancer_Homo sapiens_hsa052230.59055353
82Pancreatic cancer_Homo sapiens_hsa052120.57816563
83Shigellosis_Homo sapiens_hsa051310.56772320
84NF-kappa B signaling pathway_Homo sapiens_hsa040640.55429206
85Acute myeloid leukemia_Homo sapiens_hsa052210.54620202
86Circadian rhythm_Homo sapiens_hsa047100.54393218
87T cell receptor signaling pathway_Homo sapiens_hsa046600.53906024
88Taste transduction_Homo sapiens_hsa047420.53801576
89Endometrial cancer_Homo sapiens_hsa052130.52403971
90Proteoglycans in cancer_Homo sapiens_hsa052050.52166566
91B cell receptor signaling pathway_Homo sapiens_hsa046620.51262140
92Apoptosis_Homo sapiens_hsa042100.50790493
93Alcoholism_Homo sapiens_hsa050340.50510564
94Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.49286751
95HIF-1 signaling pathway_Homo sapiens_hsa040660.49165639
96Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.47465292
97NOD-like receptor signaling pathway_Homo sapiens_hsa046210.47119825
98Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.45997875
99Lysine degradation_Homo sapiens_hsa003100.45691317
100Hematopoietic cell lineage_Homo sapiens_hsa046400.45671664
101Central carbon metabolism in cancer_Homo sapiens_hsa052300.44688068
102Melanoma_Homo sapiens_hsa052180.44568636
103Oxidative phosphorylation_Homo sapiens_hsa001900.42887511
104Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.42839538
105FoxO signaling pathway_Homo sapiens_hsa040680.42708442
106PI3K-Akt signaling pathway_Homo sapiens_hsa041510.40438706
107Neurotrophin signaling pathway_Homo sapiens_hsa047220.39901504
108Leukocyte transendothelial migration_Homo sapiens_hsa046700.39766576
109Vitamin B6 metabolism_Homo sapiens_hsa007500.39503992
110Influenza A_Homo sapiens_hsa051640.39414706
111Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.38783769
112Olfactory transduction_Homo sapiens_hsa047400.37806511
113Glioma_Homo sapiens_hsa052140.37730981
114Regulation of actin cytoskeleton_Homo sapiens_hsa048100.37530696
115Legionellosis_Homo sapiens_hsa051340.36990405
116AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.35097842
117Renal cell carcinoma_Homo sapiens_hsa052110.34346173
118Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.33798485
119Fatty acid metabolism_Homo sapiens_hsa012120.33565946
120Asthma_Homo sapiens_hsa053100.33455990
121Platelet activation_Homo sapiens_hsa046110.33206777
122Metabolic pathways_Homo sapiens_hsa011000.32942930
123Bladder cancer_Homo sapiens_hsa052190.31927332
124Tight junction_Homo sapiens_hsa045300.31605243
125Jak-STAT signaling pathway_Homo sapiens_hsa046300.30834020
126Focal adhesion_Homo sapiens_hsa045100.30732738
127Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.30476008
128N-Glycan biosynthesis_Homo sapiens_hsa005100.29418700
129VEGF signaling pathway_Homo sapiens_hsa043700.28762031
130Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.28667072
131Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.27757981
132Nitrogen metabolism_Homo sapiens_hsa009100.27622552
133MAPK signaling pathway_Homo sapiens_hsa040100.27610420
134Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.27135358
135Folate biosynthesis_Homo sapiens_hsa007900.26179067
136Leishmaniasis_Homo sapiens_hsa051400.25920281
137Rap1 signaling pathway_Homo sapiens_hsa040150.25143826
138Toxoplasmosis_Homo sapiens_hsa051450.25115717
139Fatty acid elongation_Homo sapiens_hsa000620.24074297
140Intestinal immune network for IgA production_Homo sapiens_hsa046720.23194491
141Regulation of autophagy_Homo sapiens_hsa041400.21051884
142Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.17667594
143Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.15371069
144Ether lipid metabolism_Homo sapiens_hsa005650.15105006
145Axon guidance_Homo sapiens_hsa043600.14002388
146Fatty acid biosynthesis_Homo sapiens_hsa000610.10440927
147Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.09825944
148Alzheimers disease_Homo sapiens_hsa050100.07815929
149Longevity regulating pathway - mammal_Homo sapiens_hsa042110.07720499
150Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.07482461
151Dopaminergic synapse_Homo sapiens_hsa047280.07119332
152Glutamatergic synapse_Homo sapiens_hsa047240.06644122

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