TCERG1L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.84976828
2vocalization behavior (GO:0071625)5.73131890
3neuron cell-cell adhesion (GO:0007158)5.61737856
4behavioral response to nicotine (GO:0035095)5.26987282
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.26277653
6synaptic vesicle exocytosis (GO:0016079)5.24795820
7synaptic vesicle maturation (GO:0016188)5.07509178
8protein localization to synapse (GO:0035418)4.94810663
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.94274297
10positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.84153844
11cell migration in hindbrain (GO:0021535)4.71209990
12layer formation in cerebral cortex (GO:0021819)4.63230344
13regulation of synaptic vesicle exocytosis (GO:2000300)4.61221962
14glutamate secretion (GO:0014047)4.54270086
15regulation of glutamate receptor signaling pathway (GO:1900449)4.49803383
16dendritic spine morphogenesis (GO:0060997)4.41225118
17locomotory exploration behavior (GO:0035641)4.39846200
18proline transport (GO:0015824)4.37038328
19neuron recognition (GO:0008038)4.30406299
20ionotropic glutamate receptor signaling pathway (GO:0035235)4.29116829
21positive regulation of synaptic transmission, GABAergic (GO:0032230)4.25502185
22exploration behavior (GO:0035640)4.23670632
23pyrimidine nucleobase catabolic process (GO:0006208)4.22415955
24neuronal action potential propagation (GO:0019227)4.19594875
25neurotransmitter secretion (GO:0007269)4.14076805
26regulation of synaptic vesicle transport (GO:1902803)4.03528558
27glutamate receptor signaling pathway (GO:0007215)3.97620911
28negative regulation of microtubule polymerization (GO:0031115)3.94294716
29regulation of synapse structural plasticity (GO:0051823)3.91007794
30gamma-aminobutyric acid transport (GO:0015812)3.76167608
31synaptic transmission, glutamatergic (GO:0035249)3.75722126
32regulation of neuronal synaptic plasticity (GO:0048168)3.71232601
33axonal fasciculation (GO:0007413)3.69742942
34regulation of long-term neuronal synaptic plasticity (GO:0048169)3.69703796
35regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.66833099
36postsynaptic membrane organization (GO:0001941)3.64562226
37regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.62113676
38neurotransmitter-gated ion channel clustering (GO:0072578)3.59531922
39nucleobase catabolic process (GO:0046113)3.55986679
40synaptic vesicle docking involved in exocytosis (GO:0016081)3.51740552
41regulation of cAMP-dependent protein kinase activity (GO:2000479)3.50243607
42kidney morphogenesis (GO:0060993)3.50056259
43neuron-neuron synaptic transmission (GO:0007270)3.48845792
44neurotransmitter transport (GO:0006836)3.48134996
45DNA deamination (GO:0045006)3.45417761
46positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.42899466
47regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.40032947
48transmission of nerve impulse (GO:0019226)3.38422373
49positive regulation of membrane potential (GO:0045838)3.36535409
50L-fucose catabolic process (GO:0042355)3.35815909
51fucose catabolic process (GO:0019317)3.35815909
52L-fucose metabolic process (GO:0042354)3.35815909
53gamma-aminobutyric acid signaling pathway (GO:0007214)3.35088374
54water-soluble vitamin biosynthetic process (GO:0042364)3.34353864
55positive regulation of synapse assembly (GO:0051965)3.32909598
56dendrite morphogenesis (GO:0048813)3.32847747
57presynaptic membrane assembly (GO:0097105)3.32177454
58activation of protein kinase A activity (GO:0034199)3.26376527
59regulation of excitatory postsynaptic membrane potential (GO:0060079)3.24528250
60cerebellar Purkinje cell differentiation (GO:0021702)3.23394791
61positive regulation of dendritic spine morphogenesis (GO:0061003)3.23143089
62cellular ketone body metabolic process (GO:0046950)3.22145776
63detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.16914564
64regulation of postsynaptic membrane potential (GO:0060078)3.16740181
65regulation of dendritic spine morphogenesis (GO:0061001)3.16671532
66long-term memory (GO:0007616)3.16270407
67innervation (GO:0060384)3.14003625
68central nervous system projection neuron axonogenesis (GO:0021952)3.13330941
69regulation of synaptic transmission, GABAergic (GO:0032228)3.13169249
70social behavior (GO:0035176)3.13111748
71intraspecies interaction between organisms (GO:0051703)3.13111748
72nonmotile primary cilium assembly (GO:0035058)3.11441549
73chaperone-mediated protein transport (GO:0072321)3.11296898
74negative regulation of telomere maintenance (GO:0032205)3.10485318
75membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.09537213
76regulation of neurotransmitter levels (GO:0001505)3.07908174
77presynaptic membrane organization (GO:0097090)3.06959557
78synapse assembly (GO:0007416)3.06484382
79neuromuscular process controlling balance (GO:0050885)3.05743792
80negative regulation of dendrite morphogenesis (GO:0050774)3.05445412
81behavioral fear response (GO:0001662)3.05420267
82behavioral defense response (GO:0002209)3.05420267
83membrane depolarization during action potential (GO:0086010)3.05324961
84cerebral cortex neuron differentiation (GO:0021895)3.04831727
85regulation of neurotransmitter secretion (GO:0046928)3.04557872
86synaptic vesicle endocytosis (GO:0048488)3.03962713
87prepulse inhibition (GO:0060134)3.02375442
88regulation of vesicle fusion (GO:0031338)3.00919102
89positive regulation of synapse maturation (GO:0090129)3.00153884
90regulation of mitotic spindle checkpoint (GO:1903504)2.98653349
91regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.98653349
92regulation of synaptic transmission, glutamatergic (GO:0051966)2.97218493
93response to pheromone (GO:0019236)2.97153695
94negative regulation of cytosolic calcium ion concentration (GO:0051481)2.96818307
95cell communication by electrical coupling (GO:0010644)2.95979303
96ketone body metabolic process (GO:1902224)2.95874965
97positive regulation of action potential (GO:0045760)2.95861408
98regulation of glucokinase activity (GO:0033131)2.94070338
99regulation of hexokinase activity (GO:1903299)2.94070338
100organelle transport along microtubule (GO:0072384)2.93895480
101positive regulation of potassium ion transmembrane transport (GO:1901381)2.93885793
102learning (GO:0007612)2.93156986
103regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.92421827
104positive regulation of dendritic spine development (GO:0060999)2.92406729
105protein polyglutamylation (GO:0018095)2.92403219
106synapse organization (GO:0050808)2.92317090
107regulation of respiratory system process (GO:0044065)2.91768863
108membrane depolarization (GO:0051899)2.91678542
109mating behavior (GO:0007617)2.91524872
110mitochondrial respiratory chain complex I assembly (GO:0032981)2.91423046
111NADH dehydrogenase complex assembly (GO:0010257)2.91423046
112mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.91423046
113response to histamine (GO:0034776)2.90867741
114G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.90510276
115membrane hyperpolarization (GO:0060081)2.89884136
116axon extension (GO:0048675)2.89006861
117clathrin coat assembly (GO:0048268)2.88060188
118neuromuscular synaptic transmission (GO:0007274)2.87150831
119regulation of synapse assembly (GO:0051963)2.86990436
120neuronal ion channel clustering (GO:0045161)2.86402463
121hippocampus development (GO:0021766)2.86126076
122protein complex biogenesis (GO:0070271)2.85671928
123cellular potassium ion homeostasis (GO:0030007)2.85662651
124synaptic transmission (GO:0007268)2.84824397
125neuronal action potential (GO:0019228)2.84418599
126mannosylation (GO:0097502)2.82802040
127mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.82514364
128retinal cone cell development (GO:0046549)2.82034171
129positive regulation of meiosis (GO:0045836)2.80330962
130platelet dense granule organization (GO:0060155)2.78445479
131detection of light stimulus involved in visual perception (GO:0050908)2.76869925
132detection of light stimulus involved in sensory perception (GO:0050962)2.76869925
133epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.74900558
134startle response (GO:0001964)2.74703499
135synaptic transmission, cholinergic (GO:0007271)2.74508201
136somite rostral/caudal axis specification (GO:0032525)2.70422578
137mitochondrial respiratory chain complex assembly (GO:0033108)2.69640224
138piRNA metabolic process (GO:0034587)2.67531124
139preassembly of GPI anchor in ER membrane (GO:0016254)2.67461209
140thyroid hormone metabolic process (GO:0042403)2.66366620
141adaptation of signaling pathway (GO:0023058)2.64447545
142positive regulation of meiotic cell cycle (GO:0051446)2.63848959
143inositol phosphate catabolic process (GO:0071545)2.63610086
144protein localization to cilium (GO:0061512)2.63327299
145reflex (GO:0060004)2.63220362
146mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.63199216
147ATP synthesis coupled proton transport (GO:0015986)2.58577452
148energy coupled proton transport, down electrochemical gradient (GO:0015985)2.58577452
149respiratory chain complex IV assembly (GO:0008535)2.55869626
150negative regulation of translation, ncRNA-mediated (GO:0040033)2.55423902
151regulation of translation, ncRNA-mediated (GO:0045974)2.55423902
152negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.55423902
153epithelial cilium movement (GO:0003351)2.54862904
154photoreceptor cell maintenance (GO:0045494)2.52587066
155regulation of action potential (GO:0098900)2.52559262
156axoneme assembly (GO:0035082)2.50487712
157photoreceptor cell development (GO:0042461)2.46828003
158positive regulation of prostaglandin secretion (GO:0032308)2.46398233
159glycerophospholipid catabolic process (GO:0046475)2.43950115
160action potential (GO:0001508)2.43515832
161DNA methylation involved in gamete generation (GO:0043046)2.43293865
162dopamine transport (GO:0015872)2.42124963
163alanine transport (GO:0032328)2.42084642
164neurofilament cytoskeleton organization (GO:0060052)2.39724133
165hindbrain development (GO:0030902)2.39596088
166cilium morphogenesis (GO:0060271)2.39425302
167retina layer formation (GO:0010842)2.39298300
168behavioral response to ethanol (GO:0048149)2.39237386
169insulin secretion (GO:0030073)2.38010197
170protein neddylation (GO:0045116)2.37527102
171regulation of posttranscriptional gene silencing (GO:0060147)2.36994903
172regulation of gene silencing by miRNA (GO:0060964)2.36994903
173regulation of gene silencing by RNA (GO:0060966)2.36994903

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.81046754
2GBX2_23144817_ChIP-Seq_PC3_Human3.81571521
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.21801009
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.10883896
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.97700205
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.85706753
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.85706753
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.85053505
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.80150456
10* REST_21632747_ChIP-Seq_MESCs_Mouse2.76977981
11NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.67722453
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.56003484
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.54797791
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.48372560
15FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.47060742
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.43988119
17* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.43386803
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.38945711
19TAF15_26573619_Chip-Seq_HEK293_Human2.37820979
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.31751111
21* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.31152626
22CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.27903228
23* REST_18959480_ChIP-ChIP_MESCs_Mouse2.24357604
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.22409336
25* CTBP2_25329375_ChIP-Seq_LNCAP_Human2.20422242
26GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.05216869
27RARB_27405468_Chip-Seq_BRAIN_Mouse2.01364355
28* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.96086977
29BMI1_23680149_ChIP-Seq_NPCS_Mouse1.96003966
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.93541017
31FLI1_27457419_Chip-Seq_LIVER_Mouse1.90918016
32DROSHA_22980978_ChIP-Seq_HELA_Human1.78592842
33* EWS_26573619_Chip-Seq_HEK293_Human1.75194952
34CBX2_27304074_Chip-Seq_ESCs_Mouse1.73067578
35AR_21572438_ChIP-Seq_LNCaP_Human1.69658468
36ZFP57_27257070_Chip-Seq_ESCs_Mouse1.69247284
37RNF2_27304074_Chip-Seq_NSC_Mouse1.68372732
38HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.67591494
39ZNF274_21170338_ChIP-Seq_K562_Hela1.64512812
40PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.58624197
41IKZF1_21737484_ChIP-ChIP_HCT116_Human1.57902605
42* SMAD4_21799915_ChIP-Seq_A2780_Human1.57320922
43PCGF2_27294783_Chip-Seq_ESCs_Mouse1.56186340
44* P300_19829295_ChIP-Seq_ESCs_Human1.55363329
45EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.53074909
46MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.52379106
47* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.50304091
48ERG_21242973_ChIP-ChIP_JURKAT_Human1.46377376
49TP53_22573176_ChIP-Seq_HFKS_Human1.45240552
50SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.42477627
51GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42395542
52TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.42278888
53RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.42187091
54CBP_20019798_ChIP-Seq_JUKART_Human1.41592075
55IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.41592075
56* RING1B_27294783_Chip-Seq_ESCs_Mouse1.40952143
57MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.39046472
58EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.37271972
59SMAD_19615063_ChIP-ChIP_OVARY_Human1.37228271
60SALL1_21062744_ChIP-ChIP_HESCs_Human1.37011470
61TOP2B_26459242_ChIP-Seq_MCF-7_Human1.36592771
62MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.34789915
63* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34030468
64MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.33825904
65IGF1R_20145208_ChIP-Seq_DFB_Human1.32176726
66* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.29745954
67GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.27833198
68AR_25329375_ChIP-Seq_VCAP_Human1.27723273
69SOX2_21211035_ChIP-Seq_LN229_Gbm1.27632427
70HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.26804350
71* SMAD3_21741376_ChIP-Seq_EPCs_Human1.25497822
72RING1B_27294783_Chip-Seq_NPCs_Mouse1.25088948
73CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.23962409
74NR3C1_23031785_ChIP-Seq_PC12_Mouse1.23236350
75* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23166379
76MYC_18940864_ChIP-ChIP_HL60_Human1.22578954
77NANOG_19829295_ChIP-Seq_ESCs_Human1.22189400
78SOX2_19829295_ChIP-Seq_ESCs_Human1.22189400
79* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21878447
80TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.21400309
81FUS_26573619_Chip-Seq_HEK293_Human1.21385409
82POU3F2_20337985_ChIP-ChIP_501MEL_Human1.20930533
83KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.19677946
84PIAS1_25552417_ChIP-Seq_VCAP_Human1.18332493
85P53_22127205_ChIP-Seq_FIBROBLAST_Human1.18045098
86TCF4_22108803_ChIP-Seq_LS180_Human1.17196054
87NOTCH1_21737748_ChIP-Seq_TLL_Human1.14971775
88PCGF2_27294783_Chip-Seq_NPCs_Mouse1.14697470
89SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12919083
90NANOG_18555785_Chip-Seq_ESCs_Mouse1.12913023
91ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.12148075
92POU5F1_16153702_ChIP-ChIP_HESCs_Human1.12142701
93NFE2_27457419_Chip-Seq_LIVER_Mouse1.12078182
94NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10927113
95CDX2_19796622_ChIP-Seq_MESCs_Mouse1.09957045
96TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09442906
97POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.09442906
98ETV2_25802403_ChIP-Seq_MESCs_Mouse1.08477206
99* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.07731930
100STAT3_23295773_ChIP-Seq_U87_Human1.07425165
101GABP_17652178_ChIP-ChIP_JURKAT_Human1.06667209
102* AR_19668381_ChIP-Seq_PC3_Human1.06645837
103UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.06500503
104EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.06305447
105JUN_21703547_ChIP-Seq_K562_Human1.05740711
106CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04513027
107* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.04474521
108RBPJ_22232070_ChIP-Seq_NCS_Mouse1.03938546
109P53_22387025_ChIP-Seq_ESCs_Mouse1.03318655
110* RUNX2_22187159_ChIP-Seq_PCA_Human1.03229105
111ZFP281_18757296_ChIP-ChIP_E14_Mouse1.02991973
112EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.02892322
113TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.02197793
114EZH2_27294783_Chip-Seq_NPCs_Mouse1.01612921
115KLF5_20875108_ChIP-Seq_MESCs_Mouse1.00703584
116TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00674143
117* SMAD3_21741376_ChIP-Seq_ESCs_Human1.00652414
118PRDM14_20953172_ChIP-Seq_ESCs_Human1.00242204
119ARNT_22903824_ChIP-Seq_MCF-7_Human1.00193934
120* TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.99739025
121E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.98441660
122AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.97983158
123FOXA1_25329375_ChIP-Seq_VCAP_Human0.97796909
124FOXA1_27270436_Chip-Seq_PROSTATE_Human0.97796909
125DNAJC2_21179169_ChIP-ChIP_NT2_Human0.97739529
126BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.94393686
127TP53_20018659_ChIP-ChIP_R1E_Mouse0.93616747
128AHR_22903824_ChIP-Seq_MCF-7_Human0.92963930
129TCF4_23295773_ChIP-Seq_U87_Human0.91437116
130* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.90628982
131VDR_22108803_ChIP-Seq_LS180_Human0.90353508
132ER_23166858_ChIP-Seq_MCF-7_Human0.89254417
133* CTCF_27219007_Chip-Seq_Bcells_Human0.86781563
134SMAD4_21741376_ChIP-Seq_HESCs_Human0.85241439
135OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.84472702
136BCAT_22108803_ChIP-Seq_LS180_Human0.83096595
137KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.82695703
138FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.82667246
139RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.82118910

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.24261074
2MP0003880_abnormal_central_pattern4.36926766
3MP0003635_abnormal_synaptic_transmissio3.76851812
4MP0002735_abnormal_chemical_nociception3.48217963
5MP0001968_abnormal_touch/_nociception3.47184494
6MP0004270_analgesia3.45591784
7MP0002063_abnormal_learning/memory/cond3.06694050
8MP0009745_abnormal_behavioral_response3.03597316
9MP0002734_abnormal_mechanical_nocicepti2.96707937
10MP0006276_abnormal_autonomic_nervous2.88881527
11MP0005423_abnormal_somatic_nervous2.84842471
12MP0002064_seizures2.80334724
13MP0002572_abnormal_emotion/affect_behav2.67972199
14MP0002736_abnormal_nociception_after2.67010466
15MP0002733_abnormal_thermal_nociception2.61421653
16MP0001970_abnormal_pain_threshold2.43720398
17MP0009046_muscle_twitch2.38786646
18MP0001486_abnormal_startle_reflex2.35346235
19MP0002184_abnormal_innervation2.35026434
20MP0002272_abnormal_nervous_system2.34603894
21MP0001440_abnormal_grooming_behavior2.27300825
22MP0000778_abnormal_nervous_system2.27111625
23MP0002067_abnormal_sensory_capabilities2.08682594
24MP0003195_calcinosis2.05148440
25MP0004133_heterotaxia1.92544884
26MP0004858_abnormal_nervous_system1.90093462
27MP0002557_abnormal_social/conspecific_i1.85749163
28MP0002163_abnormal_gland_morphology1.84124820
29MP0001501_abnormal_sleep_pattern1.82706076
30MP0001529_abnormal_vocalization1.79815462
31MP0004811_abnormal_neuron_physiology1.73890388
32MP0005386_behavior/neurological_phenoty1.72016371
33MP0004924_abnormal_behavior1.72016371
34MP0000955_abnormal_spinal_cord1.71466444
35MP0003879_abnormal_hair_cell1.70500351
36MP0003329_amyloid_beta_deposits1.56298588
37MP0002882_abnormal_neuron_morphology1.56089665
38MP0001502_abnormal_circadian_rhythm1.52783171
39MP0003122_maternal_imprinting1.52301075
40MP0002638_abnormal_pupillary_reflex1.47430008
41MP0003136_yellow_coat_color1.45065189
42MP0001188_hyperpigmentation1.44743066
43MP0005379_endocrine/exocrine_gland_phen1.43996720
44MP0005253_abnormal_eye_physiology1.43083988
45MP0004742_abnormal_vestibular_system1.43046184
46MP0002066_abnormal_motor_capabilities/c1.41774280
47MP0009780_abnormal_chondrocyte_physiolo1.41393335
48MP0001984_abnormal_olfaction1.41307861
49MP0003787_abnormal_imprinting1.38109229
50MP0010386_abnormal_urinary_bladder1.37819571
51MP0008569_lethality_at_weaning1.36489218
52MP0002837_dystrophic_cardiac_calcinosis1.32806410
53MP0004142_abnormal_muscle_tone1.31742095
54MP0001905_abnormal_dopamine_level1.29518760
55MP0002822_catalepsy1.29094766
56MP0000751_myopathy1.25673295
57MP0005645_abnormal_hypothalamus_physiol1.24412805
58MP0002152_abnormal_brain_morphology1.22105972
59MP0002938_white_spotting1.21137008
60MP0005646_abnormal_pituitary_gland1.18403885
61MP0004145_abnormal_muscle_electrophysio1.17202126
62MP0004885_abnormal_endolymph1.17171665
63MP0005499_abnormal_olfactory_system1.16140826
64MP0005394_taste/olfaction_phenotype1.16140826
65MP0002928_abnormal_bile_duct1.14097636
66MP0002909_abnormal_adrenal_gland1.11983185
67MP0006072_abnormal_retinal_apoptosis1.11267745
68MP0002752_abnormal_somatic_nervous1.10605538
69MP0002751_abnormal_autonomic_nervous1.08777711
70MP0004043_abnormal_pH_regulation1.08344487
71MP0003011_delayed_dark_adaptation1.07012092
72MP0002229_neurodegeneration1.00092053
73MP0000631_abnormal_neuroendocrine_gland0.98383885
74MP0001963_abnormal_hearing_physiology0.98253760
75MP0000427_abnormal_hair_cycle0.97834111
76MP0002693_abnormal_pancreas_physiology0.96909707
77MP0005084_abnormal_gallbladder_morpholo0.95953144
78MP0001944_abnormal_pancreas_morphology0.95233288
79MP0003634_abnormal_glial_cell0.93037419
80MP0003861_abnormal_nervous_system0.90322911
81MP0005377_hearing/vestibular/ear_phenot0.89900335
82MP0003878_abnormal_ear_physiology0.89900335
83MP0008789_abnormal_olfactory_epithelium0.88934696
84MP0002069_abnormal_eating/drinking_beha0.88435421
85MP0000569_abnormal_digit_pigmentation0.88292308
86MP0005195_abnormal_posterior_eye0.87940896
87MP0005551_abnormal_eye_electrophysiolog0.87409875
88MP0006292_abnormal_olfactory_placode0.85082573
89MP0005389_reproductive_system_phenotype0.84920381
90MP0000372_irregular_coat_pigmentation0.84583976
91MP0002277_abnormal_respiratory_mucosa0.82384938
92MP0001348_abnormal_lacrimal_gland0.82310940
93MP0008995_early_reproductive_senescence0.82254502
94MP0002876_abnormal_thyroid_physiology0.81509357
95MP0001986_abnormal_taste_sensitivity0.80144295
96MP0002160_abnormal_reproductive_system0.79887685
97MP0003633_abnormal_nervous_system0.79201562
98MP0003698_abnormal_male_reproductive0.77204942
99MP0003121_genomic_imprinting0.75884998
100MP0008875_abnormal_xenobiotic_pharmacok0.75468375
101MP0000049_abnormal_middle_ear0.74577990
102MP0001299_abnormal_eye_distance/0.73405818
103MP0003631_nervous_system_phenotype0.73222080
104MP0004085_abnormal_heartbeat0.72776586
105MP0003137_abnormal_impulse_conducting0.71847812
106MP0008877_abnormal_DNA_methylation0.71405277
107MP0001485_abnormal_pinna_reflex0.70461143
108MP0001664_abnormal_digestion0.70139716
109MP0000026_abnormal_inner_ear0.69963544
110MP0008872_abnormal_physiological_respon0.68538799
111MP0003119_abnormal_digestive_system0.67644149
112MP0003283_abnormal_digestive_organ0.67636461
113MP0002653_abnormal_ependyma_morphology0.67204981
114MP0005535_abnormal_body_temperature0.64828064
115MP0009379_abnormal_foot_pigmentation0.64801836
116MP0001943_abnormal_respiration0.64715120
117MP0002102_abnormal_ear_morphology0.62665349
118MP0003123_paternal_imprinting0.61132633
119MP0003890_abnormal_embryonic-extraembry0.61017698
120MP0003938_abnormal_ear_development0.60404983
121MP0008961_abnormal_basal_metabolism0.58777553
122MP0001177_atelectasis0.57515705
123MP0002234_abnormal_pharynx_morphology0.56434119
124MP0000534_abnormal_ureter_morphology0.55258934
125MP0010770_preweaning_lethality0.54902951

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)6.54311855
2Focal motor seizures (HP:0011153)5.60489339
3Focal seizures (HP:0007359)4.84981753
4Atonic seizures (HP:0010819)4.63635165
5Epileptic encephalopathy (HP:0200134)4.16280939
6Febrile seizures (HP:0002373)4.09001507
7Visual hallucinations (HP:0002367)4.01920887
8Progressive cerebellar ataxia (HP:0002073)3.99104993
9Absence seizures (HP:0002121)3.85697394
10Molar tooth sign on MRI (HP:0002419)3.59343802
11Abnormality of midbrain morphology (HP:0002418)3.59343802
12Limb dystonia (HP:0002451)3.50895319
13Mutism (HP:0002300)3.46408922
14Dialeptic seizures (HP:0011146)3.42419427
15Decreased number of large peripheral myelinated nerve fibers (HP:0003387)3.38250634
16Action tremor (HP:0002345)3.35709198
17Hypothermia (HP:0002045)3.34483582
18Pancreatic fibrosis (HP:0100732)3.33158825
19Pancreatic cysts (HP:0001737)3.32390970
20Nephronophthisis (HP:0000090)3.28079685
21Thyroid-stimulating hormone excess (HP:0002925)3.27258503
22Supranuclear gaze palsy (HP:0000605)3.24098042
23Type II lissencephaly (HP:0007260)3.17043313
24Ankle clonus (HP:0011448)3.13904995
25True hermaphroditism (HP:0010459)3.10134174
26Generalized tonic-clonic seizures (HP:0002069)3.09380630
27Termporal pattern (HP:0011008)3.08970681
28Insidious onset (HP:0003587)3.08970681
29Acute necrotizing encephalopathy (HP:0006965)2.93112354
30Polyphagia (HP:0002591)2.91743458
31Amblyopia (HP:0000646)2.91397788
32Progressive macrocephaly (HP:0004481)2.84797339
33Excessive salivation (HP:0003781)2.83899272
34Drooling (HP:0002307)2.83899272
35Abnormality of the corticospinal tract (HP:0002492)2.83391280
36Pheochromocytoma (HP:0002666)2.82884710
37Congenital stationary night blindness (HP:0007642)2.81701207
38Depression (HP:0000716)2.81399350
39Broad-based gait (HP:0002136)2.78150384
40Anxiety (HP:0000739)2.77629784
41Abnormal gallbladder physiology (HP:0012438)2.75364108
42Cholecystitis (HP:0001082)2.75364108
43Agitation (HP:0000713)2.73349744
44Abnormality of the renal medulla (HP:0100957)2.73266304
45Abnormal eating behavior (HP:0100738)2.71665403
46Polyuria (HP:0000103)2.64390306
47Polydipsia (HP:0001959)2.64147191
48Abnormal drinking behavior (HP:0030082)2.64147191
49Urinary bladder sphincter dysfunction (HP:0002839)2.63908236
50Medial flaring of the eyebrow (HP:0010747)2.63269476
51Peripheral hypomyelination (HP:0007182)2.58485750
52Decreased circulating renin level (HP:0003351)2.57534522
53Abnormality of the renal cortex (HP:0011035)2.56475256
54Amyotrophic lateral sclerosis (HP:0007354)2.55497492
55Aplasia/Hypoplasia of the brainstem (HP:0007362)2.53226179
56Hypoplasia of the brainstem (HP:0002365)2.53226179
57Ulnar claw (HP:0001178)2.51854771
58Hyperventilation (HP:0002883)2.51386410
59Mitochondrial inheritance (HP:0001427)2.50506072
60Hyperthyroidism (HP:0000836)2.50031783
61Methylmalonic acidemia (HP:0002912)2.49020858
62Truncal ataxia (HP:0002078)2.47895854
63Neuroendocrine neoplasm (HP:0100634)2.47115896
64Acute encephalopathy (HP:0006846)2.45624647
65Abnormality of the lower motor neuron (HP:0002366)2.45479957
66Hypoventilation (HP:0002791)2.44862879
67Dysdiadochokinesis (HP:0002075)2.41330327
68Abnormal mitochondria in muscle tissue (HP:0008316)2.39863095
69Torticollis (HP:0000473)2.38074020
70Impaired vibration sensation in the lower limbs (HP:0002166)2.38061329
71Dysmetria (HP:0001310)2.37222065
72Failure to thrive in infancy (HP:0001531)2.37221099
73Large for gestational age (HP:0001520)2.36465418
74Gait imbalance (HP:0002141)2.35738894
75Urinary urgency (HP:0000012)2.34151565
76Papilledema (HP:0001085)2.32571449
77Akinesia (HP:0002304)2.31906546
78Fetal akinesia sequence (HP:0001989)2.30133761
79Hypokalemic alkalosis (HP:0001949)2.28903962
80Progressive inability to walk (HP:0002505)2.28501604
81Focal dystonia (HP:0004373)2.27748534
82Shoulder girdle muscle weakness (HP:0003547)2.26708966
83Spastic gait (HP:0002064)2.26442819
84Abnormality of the labia minora (HP:0012880)2.25067999
85Genetic anticipation (HP:0003743)2.24374695
86Poor eye contact (HP:0000817)2.23835492
87Cystic liver disease (HP:0006706)2.23107180
88Craniofacial dystonia (HP:0012179)2.22657264
89Neoplasm of the adrenal cortex (HP:0100641)2.18878139
90Neurofibrillary tangles (HP:0002185)2.18371626
91Gaze-evoked nystagmus (HP:0000640)2.17407271
92Cerebral inclusion bodies (HP:0100314)2.17181880
93Hyperinsulinemic hypoglycemia (HP:0000825)2.16833322
94Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.16091483
95Specific learning disability (HP:0001328)2.15879919
96Hemiparesis (HP:0001269)2.15811846
97Optic nerve hypoplasia (HP:0000609)2.14982638
98Increased CSF lactate (HP:0002490)2.14342677
99Epileptiform EEG discharges (HP:0011182)2.13402289
100Chronic hepatic failure (HP:0100626)2.13322657
101Abolished electroretinogram (ERG) (HP:0000550)2.12962972
102EEG with generalized epileptiform discharges (HP:0011198)2.12960893
103Abnormality of renin-angiotensin system (HP:0000847)2.12567453
104Impaired social interactions (HP:0000735)2.12132950
105Abnormal social behavior (HP:0012433)2.12132950
106Megalencephaly (HP:0001355)2.11591021
107Abnormal urine output (HP:0012590)2.10410349
108Hypsarrhythmia (HP:0002521)2.07661004
109Delusions (HP:0000746)2.06618589
110Sclerocornea (HP:0000647)2.06418997
111Hypomagnesemia (HP:0002917)2.06403461
112Methylmalonic aciduria (HP:0012120)2.04176112
113Congenital primary aphakia (HP:0007707)2.02482245
114Renal salt wasting (HP:0000127)2.00273149
115Metabolic alkalosis (HP:0200114)1.98268346
116Cutaneous finger syndactyly (HP:0010554)1.97670416
117Genital tract atresia (HP:0001827)1.97156785
118Bradykinesia (HP:0002067)1.96147477
119Bilateral microphthalmos (HP:0007633)1.95586657
120Scanning speech (HP:0002168)1.95287306
121Hyperaldosteronism (HP:0000859)1.95216318
122Anencephaly (HP:0002323)1.94914882
123Occipital encephalocele (HP:0002085)1.94027086
124Attenuation of retinal blood vessels (HP:0007843)1.93960536
125Ketoacidosis (HP:0001993)1.93951916
126Optic disc pallor (HP:0000543)1.93536585
127Vaginal atresia (HP:0000148)1.93059295
128Morphological abnormality of the pyramidal tract (HP:0002062)1.92707210
129Absent speech (HP:0001344)1.92501660
130Lissencephaly (HP:0001339)1.92116484
131Hepatocellular necrosis (HP:0001404)1.91910300
132Tubular atrophy (HP:0000092)1.91249474
133Bony spicule pigmentary retinopathy (HP:0007737)1.90239106
134Retinal dysplasia (HP:0007973)1.89781911
135Diplopia (HP:0000651)1.89581989
136Abnormality of binocular vision (HP:0011514)1.89581989
137Myotonia (HP:0002486)1.89493800
138Lower limb muscle weakness (HP:0007340)1.86726007
139Hypercortisolism (HP:0001578)1.86693985
140Lipid accumulation in hepatocytes (HP:0006561)1.86591277
141Psychosis (HP:0000709)1.85702652
142Nephrogenic diabetes insipidus (HP:0009806)1.85102725
143Sleep apnea (HP:0010535)1.85076586
144Inability to walk (HP:0002540)1.84981698
145Abnormality of salivation (HP:0100755)1.84394169
146Hepatic necrosis (HP:0002605)1.84003941
147Intestinal atresia (HP:0011100)1.83886887
148Abnormal rod and cone electroretinograms (HP:0008323)1.83416603
149Neoplasm of the peripheral nervous system (HP:0100007)1.83165806
150Ventricular fibrillation (HP:0001663)1.82944490
151Postural instability (HP:0002172)1.82869971
152Colon cancer (HP:0003003)1.82783301
1533-Methylglutaconic aciduria (HP:0003535)1.82210871
154Abnormal pancreas size (HP:0012094)1.79921492
155Increased hepatocellular lipid droplets (HP:0006565)1.78335067
156Hyperactive renin-angiotensin system (HP:0000841)1.78051959
157Concave nail (HP:0001598)1.77703193
158Pachygyria (HP:0001302)1.77226766
159Pendular nystagmus (HP:0012043)1.76986702
160Decreased central vision (HP:0007663)1.76748559
161Impaired pain sensation (HP:0007328)1.76319233
162Abnormality of pain sensation (HP:0010832)1.76319233
163Stereotypic behavior (HP:0000733)1.75551076
164Incomplete penetrance (HP:0003829)1.75285400
165Bile duct proliferation (HP:0001408)1.75268447
166Abnormal biliary tract physiology (HP:0012439)1.75268447
167Apathy (HP:0000741)1.75181888
168Abnormality of renal excretion (HP:0011036)1.74962393
169Aplasia/Hypoplasia of the fovea (HP:0008060)1.74452153
170Hypoplasia of the fovea (HP:0007750)1.74452153
171Esotropia (HP:0000565)1.73411674
172Abnormality of the pons (HP:0007361)1.72845044
173Goiter (HP:0000853)1.72104662
174Hypoplasia of the pons (HP:0012110)1.71115927

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.11899374
2MARK14.73803337
3NTRK33.68003796
4MAP3K93.50536500
5MAP3K43.29248076
6MINK12.90666017
7PINK12.74024814
8MAP2K72.73345759
9MAPK132.55123088
10EPHA42.49998846
11KSR22.42411639
12NTRK22.34103954
13CASK2.27225250
14GRK12.24581641
15PNCK2.23384292
16MAP3K122.23357826
17PAK62.10068277
18ZAK2.06179860
19MAP2K41.98462944
20LATS21.96677010
21DAPK21.96155435
22TRIM281.89593949
23GRK51.88131229
24PHKG11.86082213
25PHKG21.86082213
26NUAK11.85235793
27FGFR21.84035661
28KSR11.79783500
29DYRK21.70894008
30NTRK11.62301289
31WNK41.61616293
32MKNK21.60593169
33PASK1.60247198
34CDK191.53663161
35UHMK11.48416835
36SIK21.43511330
37MAP3K61.40409337
38PLK21.37562755
39CDK51.36285431
40MST41.27210960
41MAP3K21.27102723
42MUSK1.21712212
43ACVR1B1.17032219
44DAPK11.15836403
45TLK11.15537078
46LIMK11.14081701
47LMTK21.11807026
48TNIK1.11795275
49ERBB31.07719458
50ARAF1.07712500
51CDK141.06492858
52STK391.06356167
53PRKCG1.05100195
54PAK31.04876932
55RET1.01480201
56MAP4K20.99987950
57CDK180.95197358
58NME10.94143996
59INSRR0.92764007
60TSSK60.92375043
61CDK150.91935728
62CSNK1G20.91845728
63BCKDK0.89493341
64TAOK10.89273441
65CSNK1G10.88126294
66MAPK150.87840259
67CAMK2A0.87311184
68PLK30.87244110
69TAOK30.85581289
70CAMKK10.84924636
71PTK2B0.81622508
72VRK10.81381283
73CDK11A0.80506571
74GRK70.80437695
75OXSR10.77868882
76DYRK1A0.77504264
77MKNK10.76396904
78STK380.76127324
79PRKD30.75993193
80NLK0.74946993
81TIE10.74663215
82RIPK40.72907543
83FES0.70153417
84MAPKAPK50.69317207
85BCR0.68993427
86ADRBK10.68313746
87EPHB20.67419505
88WNK30.64582497
89MARK20.63315792
90MAP2K20.63077208
91MAP2K10.62015283
92STK110.60135454
93CAMK2B0.59844377
94CSNK1G30.59119346
95STK38L0.56892487
96SGK2230.54839732
97SGK4940.54839732
98RAF10.54653933
99CSNK1A10.53163431
100PRKCZ0.52360695
101PLK40.52307689
102TXK0.51953095
103MAPK120.51232546
104BMPR1B0.51173147
105CCNB10.51127527
106PRKCE0.49905992
107PRKCI0.49050695
108FER0.48553775
109ADRBK20.48435103
110AKT30.47776858
111ALK0.47688512
112NEK10.46334353
113NEK20.44273270
114TYRO30.43872539
115PRPF4B0.43423964
116RPS6KA20.43419744
117CAMK10.42574663
118SIK30.42125689
119PRKG10.41632759
120CAMKK20.41532766
121PLK10.40083974
122RPS6KA30.39371528
123PKN10.38811337
124PRKCA0.38239258
125CAMK1D0.38039538
126CSNK1E0.37953604
127CSNK1A1L0.37379215
128CDK30.37329154
129MAP2K60.37305174
130ICK0.35826149
131BMPR20.35685668
132VRK20.35672404
133ROCK20.35404751
134TGFBR10.35304155
135SGK10.35155639
136PRKACA0.34850746
137BRAF0.34695987
138CSNK1D0.34087450
139SGK20.34083643
140SCYL20.33833297
141MAPK100.33394937
142RPS6KA50.32940598
143MAP3K10.32835727
144PRKCH0.32676824
145PRKACB0.32326500
146FGR0.31413077
147CAMK1G0.31051728
148CAMK40.30792141
149PRKCB0.30683611
150TAF10.30569213

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.06069020
2Synaptic vesicle cycle_Homo sapiens_hsa047213.70304702
3Maturity onset diabetes of the young_Homo sapiens_hsa049503.36794812
4GABAergic synapse_Homo sapiens_hsa047272.71945776
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.69789688
6Olfactory transduction_Homo sapiens_hsa047402.45572772
7Long-term potentiation_Homo sapiens_hsa047202.42573128
8Glutamatergic synapse_Homo sapiens_hsa047242.35873229
9Morphine addiction_Homo sapiens_hsa050322.34685147
10Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.33617898
11Circadian entrainment_Homo sapiens_hsa047132.32641937
12Protein export_Homo sapiens_hsa030602.31220955
13Selenocompound metabolism_Homo sapiens_hsa004502.20709611
14Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.19370980
15Dopaminergic synapse_Homo sapiens_hsa047282.13037508
16Taste transduction_Homo sapiens_hsa047422.05064592
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.04678147
18Collecting duct acid secretion_Homo sapiens_hsa049662.01305386
19Amphetamine addiction_Homo sapiens_hsa050311.96864084
20Serotonergic synapse_Homo sapiens_hsa047261.83350924
21Salivary secretion_Homo sapiens_hsa049701.82330771
22Linoleic acid metabolism_Homo sapiens_hsa005911.80696795
23Cholinergic synapse_Homo sapiens_hsa047251.80272313
24Insulin secretion_Homo sapiens_hsa049111.78696084
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.75790080
26Oxidative phosphorylation_Homo sapiens_hsa001901.71310224
27Cardiac muscle contraction_Homo sapiens_hsa042601.68173854
28Long-term depression_Homo sapiens_hsa047301.64589006
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.63674943
30alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.62457144
31Axon guidance_Homo sapiens_hsa043601.52629596
32RNA polymerase_Homo sapiens_hsa030201.52477651
33Gastric acid secretion_Homo sapiens_hsa049711.47055462
34Tryptophan metabolism_Homo sapiens_hsa003801.46610171
35GnRH signaling pathway_Homo sapiens_hsa049121.45712218
36Aldosterone synthesis and secretion_Homo sapiens_hsa049251.43812475
37Oxytocin signaling pathway_Homo sapiens_hsa049211.39146859
38Parkinsons disease_Homo sapiens_hsa050121.38208564
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.36967330
40Gap junction_Homo sapiens_hsa045401.36824379
41Renin secretion_Homo sapiens_hsa049241.34721561
42Cocaine addiction_Homo sapiens_hsa050301.32406082
43Basal transcription factors_Homo sapiens_hsa030221.31692384
44Alzheimers disease_Homo sapiens_hsa050101.31633624
45Calcium signaling pathway_Homo sapiens_hsa040201.29868251
46Ether lipid metabolism_Homo sapiens_hsa005651.26702602
47Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.25751064
48Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.24401387
49Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.21847707
50Propanoate metabolism_Homo sapiens_hsa006401.20307904
51Ribosome_Homo sapiens_hsa030101.20159778
52Oocyte meiosis_Homo sapiens_hsa041141.19302980
53Type II diabetes mellitus_Homo sapiens_hsa049301.17090910
54Vitamin B6 metabolism_Homo sapiens_hsa007501.14679097
55Vibrio cholerae infection_Homo sapiens_hsa051101.13628317
56Huntingtons disease_Homo sapiens_hsa050161.10915698
57Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.10624486
58Proteasome_Homo sapiens_hsa030501.07609092
59Estrogen signaling pathway_Homo sapiens_hsa049151.07259259
60Nitrogen metabolism_Homo sapiens_hsa009101.04834152
61Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.03626279
62Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.02818898
63Fanconi anemia pathway_Homo sapiens_hsa034601.02737734
64ErbB signaling pathway_Homo sapiens_hsa040121.02062533
65Phototransduction_Homo sapiens_hsa047441.01691962
66Glioma_Homo sapiens_hsa052141.01327394
67Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.00144396
68Regulation of autophagy_Homo sapiens_hsa041400.99424181
69RNA degradation_Homo sapiens_hsa030180.99364783
70Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.99361004
71Homologous recombination_Homo sapiens_hsa034400.98959925
72Melanogenesis_Homo sapiens_hsa049160.98146406
73Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.95059725
74cAMP signaling pathway_Homo sapiens_hsa040240.95045972
75Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.87619888
76Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.84962056
77Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.84280621
78One carbon pool by folate_Homo sapiens_hsa006700.81406921
79Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.81082477
80Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.80948114
81beta-Alanine metabolism_Homo sapiens_hsa004100.80635076
82cGMP-PKG signaling pathway_Homo sapiens_hsa040220.80222123
83Peroxisome_Homo sapiens_hsa041460.80084115
84Dorso-ventral axis formation_Homo sapiens_hsa043200.78545686
85Folate biosynthesis_Homo sapiens_hsa007900.75935834
86Arachidonic acid metabolism_Homo sapiens_hsa005900.74419122
87Renal cell carcinoma_Homo sapiens_hsa052110.73649617
88Caffeine metabolism_Homo sapiens_hsa002320.73432013
89Non-homologous end-joining_Homo sapiens_hsa034500.71663094
90Vascular smooth muscle contraction_Homo sapiens_hsa042700.68827285
91Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.68472572
92MAPK signaling pathway_Homo sapiens_hsa040100.68340491
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.68263376
94Colorectal cancer_Homo sapiens_hsa052100.66588649
95Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66296367
96Phosphatidylinositol signaling system_Homo sapiens_hsa040700.66262288
97Endometrial cancer_Homo sapiens_hsa052130.63935530
98Purine metabolism_Homo sapiens_hsa002300.63636903
99Alcoholism_Homo sapiens_hsa050340.62523337
100Thyroid hormone synthesis_Homo sapiens_hsa049180.62080374
101Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.61422854
102Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.61273496
103Neurotrophin signaling pathway_Homo sapiens_hsa047220.61046299
104Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.59122148
105Insulin signaling pathway_Homo sapiens_hsa049100.58736246
106ABC transporters_Homo sapiens_hsa020100.57962459
107Dilated cardiomyopathy_Homo sapiens_hsa054140.57080907
108Ras signaling pathway_Homo sapiens_hsa040140.57022780
109Wnt signaling pathway_Homo sapiens_hsa043100.56417303
110Sulfur metabolism_Homo sapiens_hsa009200.56013656
111VEGF signaling pathway_Homo sapiens_hsa043700.55826043
112Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.54879285
113Retinol metabolism_Homo sapiens_hsa008300.54636246
114Metabolic pathways_Homo sapiens_hsa011000.53693813
115Chemical carcinogenesis_Homo sapiens_hsa052040.53241198
116Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.52428761
117Phospholipase D signaling pathway_Homo sapiens_hsa040720.52079064
118Glucagon signaling pathway_Homo sapiens_hsa049220.50307853
119Choline metabolism in cancer_Homo sapiens_hsa052310.50094193
120Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.48247304
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.47361991
122Prion diseases_Homo sapiens_hsa050200.46790799
123Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.46778589
124Fat digestion and absorption_Homo sapiens_hsa049750.45587842
125Pancreatic secretion_Homo sapiens_hsa049720.43074977
126Histidine metabolism_Homo sapiens_hsa003400.42903185
127Endocytosis_Homo sapiens_hsa041440.42644278
128Rap1 signaling pathway_Homo sapiens_hsa040150.42308087
129Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.42172520
130Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.42111525
131Hedgehog signaling pathway_Homo sapiens_hsa043400.40988567
132Central carbon metabolism in cancer_Homo sapiens_hsa052300.40490319
133Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.39540310
134Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.39166733
135Ovarian steroidogenesis_Homo sapiens_hsa049130.38213318
136Melanoma_Homo sapiens_hsa052180.37989889
137Butanoate metabolism_Homo sapiens_hsa006500.37860228
138Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.36723541
139Circadian rhythm_Homo sapiens_hsa047100.36245643
140Type I diabetes mellitus_Homo sapiens_hsa049400.36176900
141Thyroid hormone signaling pathway_Homo sapiens_hsa049190.36151132
142Cysteine and methionine metabolism_Homo sapiens_hsa002700.36145117
143Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.35230391
144Steroid hormone biosynthesis_Homo sapiens_hsa001400.34528244
145Phagosome_Homo sapiens_hsa041450.34423979
146Non-small cell lung cancer_Homo sapiens_hsa052230.32782476
147Sulfur relay system_Homo sapiens_hsa041220.32299455
148mTOR signaling pathway_Homo sapiens_hsa041500.31678833
149Fatty acid elongation_Homo sapiens_hsa000620.31289723
150Primary bile acid biosynthesis_Homo sapiens_hsa001200.30684268

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