TCF19

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein that contains a PHD-type zinc finger domain and likely functions as a transcription factor. The encoded protein plays a role proliferation and apoptosis of pancreatic beta cells. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)7.14499014
2telomere maintenance via semi-conservative replication (GO:0032201)6.98798633
3DNA unwinding involved in DNA replication (GO:0006268)6.97383391
4DNA strand elongation (GO:0022616)6.76179509
5mitotic recombination (GO:0006312)6.33307640
6telomere maintenance via recombination (GO:0000722)6.20116709
7DNA replication initiation (GO:0006270)6.08423571
8protein localization to kinetochore (GO:0034501)5.58598209
9nucleotide-excision repair, DNA gap filling (GO:0006297)5.48323293
10DNA replication checkpoint (GO:0000076)5.47741790
11telomere maintenance via telomere lengthening (GO:0010833)5.15355776
12regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)5.14307517
13mitotic chromosome condensation (GO:0007076)5.12814385
14protein localization to chromosome, centromeric region (GO:0071459)4.74537400
15DNA replication-dependent nucleosome organization (GO:0034723)4.67564302
16DNA replication-dependent nucleosome assembly (GO:0006335)4.67564302
17deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.49859092
18mitotic sister chromatid segregation (GO:0000070)4.49290307
19CENP-A containing nucleosome assembly (GO:0034080)4.45614388
20sister chromatid segregation (GO:0000819)4.40457999
21translesion synthesis (GO:0019985)4.36469149
22chromatin remodeling at centromere (GO:0031055)4.34365229
23DNA replication-independent nucleosome assembly (GO:0006336)4.32066536
24DNA replication-independent nucleosome organization (GO:0034724)4.32066536
25attachment of spindle microtubules to kinetochore (GO:0008608)4.28175926
26kinetochore organization (GO:0051383)4.01629172
27deoxyribonucleotide biosynthetic process (GO:0009263)3.90738826
28telomere maintenance (GO:0000723)3.87052213
29telomere organization (GO:0032200)3.85228069
30pore complex assembly (GO:0046931)3.73982230
31postreplication repair (GO:0006301)3.73648662
32establishment of viral latency (GO:0019043)3.69735678
33regulation of double-strand break repair via homologous recombination (GO:0010569)3.68907416
34regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.68156517
35regulation of mitotic spindle organization (GO:0060236)3.66907938
36DNA duplex unwinding (GO:0032508)3.63850562
37DNA geometric change (GO:0032392)3.62649842
38chromatin assembly or disassembly (GO:0006333)3.59982830
39mitotic metaphase plate congression (GO:0007080)3.59729981
40nucleobase-containing small molecule interconversion (GO:0015949)3.59635411
41regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.58364220
42ribosomal small subunit assembly (GO:0000028)3.57740332
43regulation of translational fidelity (GO:0006450)3.55634366
44chromosome condensation (GO:0030261)3.55168662
45base-excision repair (GO:0006284)3.54385213
46folic acid-containing compound biosynthetic process (GO:0009396)3.53345995
47mismatch repair (GO:0006298)3.50725015
48mitotic nuclear envelope disassembly (GO:0007077)3.50234218
49histone exchange (GO:0043486)3.46121776
50mitotic sister chromatid cohesion (GO:0007064)3.45683569
51histone-serine phosphorylation (GO:0035404)3.40658329
52Golgi transport vesicle coating (GO:0048200)3.40389594
53COPI coating of Golgi vesicle (GO:0048205)3.40389594
54positive regulation of chromosome segregation (GO:0051984)3.40130137
55heterochromatin organization (GO:0070828)3.39695588
56meiotic chromosome segregation (GO:0045132)3.35226104
57DNA synthesis involved in DNA repair (GO:0000731)3.34153384
58establishment of chromosome localization (GO:0051303)3.32808443
59metaphase plate congression (GO:0051310)3.30916439
60DNA topological change (GO:0006265)3.30456032
61DNA conformation change (GO:0071103)3.29555532
62regulation of DNA endoreduplication (GO:0032875)3.29247511
63protein localization to chromosome (GO:0034502)3.27161442
64chromosome segregation (GO:0007059)3.24994488
65dosage compensation (GO:0007549)3.24247936
66membrane disassembly (GO:0030397)3.23522657
67nuclear envelope disassembly (GO:0051081)3.23522657
68IMP biosynthetic process (GO:0006188)3.23425469
69mitotic cell cycle (GO:0000278)3.21233931
70protein maturation by protein folding (GO:0022417)3.19475984
71nucleobase biosynthetic process (GO:0046112)3.16335452
72regulation of translational termination (GO:0006449)3.15884649
73kinetochore assembly (GO:0051382)3.15722944
74G1/S transition of mitotic cell cycle (GO:0000082)3.14432153
75cell cycle G1/S phase transition (GO:0044843)3.14432153
76regulation of mammary gland epithelial cell proliferation (GO:0033599)3.14201991
77DNA packaging (GO:0006323)3.12601938
78viral transcription (GO:0019083)3.12377869
79negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.11797224
80positive regulation of DNA-dependent DNA replication (GO:2000105)3.10704896
81folic acid metabolic process (GO:0046655)3.10158757
82DNA replication (GO:0006260)3.10120248
83regulation of spindle organization (GO:0090224)3.09039332
84spliceosomal tri-snRNP complex assembly (GO:0000244)3.07395708
85mitotic nuclear envelope reassembly (GO:0007084)3.06714499
86nuclear envelope reassembly (GO:0031468)3.06714499
87transcription-coupled nucleotide-excision repair (GO:0006283)3.05486666
88somatic diversification of immune receptors via somatic mutation (GO:0002566)3.04343374
89somatic hypermutation of immunoglobulin genes (GO:0016446)3.04343374
90translational termination (GO:0006415)3.03666154
91negative regulation of RNA splicing (GO:0033119)3.03243893
92ATP-dependent chromatin remodeling (GO:0043044)3.02758074
93regulation of protein heterodimerization activity (GO:0043497)3.01250683
94ribosomal small subunit biogenesis (GO:0042274)2.99591226
95regulation of chromosome segregation (GO:0051983)2.98369282
96nuclear envelope organization (GO:0006998)2.97866747
97ribosome assembly (GO:0042255)2.94743325
98nuclear pore organization (GO:0006999)2.92773807
99regulation of nuclear cell cycle DNA replication (GO:0033262)2.91758311
100formation of translation preinitiation complex (GO:0001731)2.91093795
101mitotic G1 DNA damage checkpoint (GO:0031571)2.90779718
102regulation of sister chromatid cohesion (GO:0007063)2.88092999
103nucleosome assembly (GO:0006334)2.87632121
104regulation of centrosome cycle (GO:0046605)2.87415908
105deoxyribose phosphate biosynthetic process (GO:0046385)2.86921208
1062-deoxyribonucleotide biosynthetic process (GO:0009265)2.86921208
107regulation of double-strand break repair (GO:2000779)2.85787158
108mitotic DNA integrity checkpoint (GO:0044774)2.84523186
109protein complex localization (GO:0031503)2.83868675
110spindle checkpoint (GO:0031577)2.83249977
111cellular protein complex localization (GO:0034629)2.83056498
112pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.81368172
113chromosome organization (GO:0051276)2.80597035
114maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.80588676
115nuclear pore complex assembly (GO:0051292)2.79901167
116proline biosynthetic process (GO:0006561)2.78414906
117translational elongation (GO:0006414)2.78397248
118negative regulation of cell cycle G2/M phase transition (GO:1902750)2.77769528
119establishment of integrated proviral latency (GO:0075713)2.77748207
120negative regulation of mRNA processing (GO:0050686)2.77618264
121DNA ligation (GO:0006266)2.76853841
122non-recombinational repair (GO:0000726)2.72073032
123double-strand break repair via nonhomologous end joining (GO:0006303)2.72073032
124DNA biosynthetic process (GO:0071897)2.71192894
125spindle organization (GO:0007051)2.70901815
126protein K6-linked ubiquitination (GO:0085020)2.70893410
127negative regulation of chromosome segregation (GO:0051985)2.70170013
128histone phosphorylation (GO:0016572)2.66605644
129positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.66546357
130positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.66546357
131positive regulation of mitotic sister chromatid separation (GO:1901970)2.66546357

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.58079754
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.37148463
3FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.59345044
4* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.53002247
5MYC_18555785_ChIP-Seq_MESCs_Mouse2.98920758
6AR_21909140_ChIP-Seq_LNCAP_Human2.56911602
7E2F1_21310950_ChIP-Seq_MCF-7_Human2.47499624
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.31948464
9MYC_22102868_ChIP-Seq_BL_Human2.24956332
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.24296279
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.07793271
12MYC_18358816_ChIP-ChIP_MESCs_Mouse2.07319640
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.05403189
14E2F7_22180533_ChIP-Seq_HELA_Human12.7524222
15SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.99183619
16ELF1_17652178_ChIP-ChIP_JURKAT_Human1.97844584
17EST1_17652178_ChIP-ChIP_JURKAT_Human1.93819667
18XRN2_22483619_ChIP-Seq_HELA_Human1.92997830
19NELFA_20434984_ChIP-Seq_ESCs_Mouse1.88571367
20CREB1_15753290_ChIP-ChIP_HEK293T_Human1.88454021
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.76574201
22SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.74986240
23GABP_17652178_ChIP-ChIP_JURKAT_Human1.72697701
24VDR_21846776_ChIP-Seq_THP-1_Human1.71899381
25FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.69326211
26DCP1A_22483619_ChIP-Seq_HELA_Human1.66279023
27ETS1_20019798_ChIP-Seq_JURKAT_Human1.63878474
28MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.62866611
29ZNF263_19887448_ChIP-Seq_K562_Human1.62337878
30TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.59390331
31VDR_23849224_ChIP-Seq_CD4+_Human1.58076647
32MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.56797978
33JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.56192300
34FOXP3_21729870_ChIP-Seq_TREG_Human1.54999929
35SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.50279459
36E2F1_18555785_ChIP-Seq_MESCs_Mouse1.45662005
37CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.45542846
38CIITA_25753668_ChIP-Seq_RAJI_Human1.43876818
39MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.43763785
40ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.40383596
41TTF2_22483619_ChIP-Seq_HELA_Human1.39789993
42GABP_19822575_ChIP-Seq_HepG2_Human1.36137105
43HOXB4_20404135_ChIP-ChIP_EML_Mouse1.34600571
44* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.32624448
45MYCN_18555785_ChIP-Seq_MESCs_Mouse1.31344180
46ELK3_25401928_ChIP-Seq_HUVEC_Human1.30079775
47NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.28955806
48ERG_20887958_ChIP-Seq_HPC-7_Mouse1.28626140
49ZFX_18555785_ChIP-Seq_MESCs_Mouse1.27554273
50SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.24945429
51ELK1_19687146_ChIP-ChIP_HELA_Human1.23253428
52PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.23166276
53E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.23066659
54NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.21805560
55THAP11_20581084_ChIP-Seq_MESCs_Mouse1.20846368
56TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.20508288
57FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.19741633
58FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.16537246
59MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.15527448
60MAF_26560356_Chip-Seq_TH1_Human1.15100910
61STAT3_1855785_ChIP-Seq_MESCs_Mouse1.14900147
62* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.14860742
63* TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.14647088
64KDM5A_27292631_Chip-Seq_BREAST_Human1.13978686
65IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.13882388
66KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.13442904
67NANOG_18555785_ChIP-Seq_MESCs_Mouse1.12738476
68CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.10636404
69KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.07952393
70NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.07650226
71UTX_26944678_Chip-Seq_JUKART_Human1.07567492
72MYB_26560356_Chip-Seq_TH2_Human1.07493537
73KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.07492439
74TP63_17297297_ChIP-ChIP_HaCaT_Human1.06811635
75SPI1_23547873_ChIP-Seq_NB4_Human1.06501660
76PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.03809734
77GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.03168811
78* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.02081385
79STAT4_19710469_ChIP-ChIP_TH1__Mouse1.02028609
80TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.01854783
81ESR1_15608294_ChIP-ChIP_MCF-7_Human1.01080870
82VDR_24763502_ChIP-Seq_THP-1_Human1.00175422
83SCL_19346495_ChIP-Seq_HPC-7_Human0.99320076
84* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.99306674
85* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.98885676
86POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.98784572
87CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.98634362
88YY1_21170310_ChIP-Seq_MESCs_Mouse0.98569224
89RACK7_27058665_Chip-Seq_MCF-7_Human0.98255977
90TFEB_21752829_ChIP-Seq_HELA_Human0.97648698
91CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.96846925
92TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.96814076
93ATF3_27146783_Chip-Seq_COLON_Human0.96228529
94HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.95126403
95HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.93709754
96MYB_26560356_Chip-Seq_TH1_Human0.93390268
97TBX5_21415370_ChIP-Seq_HL-1_Mouse0.93222505
98PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.92910177
99TP63_19390658_ChIP-ChIP_HaCaT_Human0.92472695
100POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.92396551
101BRD4_27068464_Chip-Seq_AML-cells_Mouse0.91983858
102* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.91633648
103GATA1_22383799_ChIP-Seq_G1ME_Mouse0.91319992
104MYB_21317192_ChIP-Seq_ERMYB_Mouse0.90269976
105LXR_22292898_ChIP-Seq_THP-1_Human0.90153152
106YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.89583364
107SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.88083623
108IRF8_22096565_ChIP-ChIP_GC-B_Human0.87743499
109SRY_22984422_ChIP-ChIP_TESTIS_Rat0.87648511
110NCOR1_26117541_ChIP-Seq_K562_Human0.87281123
111RARG_19884340_ChIP-ChIP_MEFs_Mouse0.87112726
112CHD1_26751641_Chip-Seq_LNCaP_Human0.86809862
113TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.84843640
114* TET1_21451524_ChIP-Seq_MESCs_Mouse0.84820042
115KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.84510926
116PADI4_21655091_ChIP-ChIP_MCF-7_Human0.83471715
117* KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.83005276
118TCF7_22412390_ChIP-Seq_EML_Mouse0.82416414
119CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.82240328
120MAF_26560356_Chip-Seq_TH2_Human0.82138922
121CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.81344760
122RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.81325349
123RUNX1_22412390_ChIP-Seq_EML_Mouse0.80594690
124SRF_21415370_ChIP-Seq_HL-1_Mouse0.79748908
125SOX2_18555785_ChIP-Seq_MESCs_Mouse0.78766198
126MYC_18940864_ChIP-ChIP_HL60_Human0.78351789
127IRF8_21731497_ChIP-ChIP_J774_Mouse0.76490613
128HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.75699086

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.17953995
2MP0003111_abnormal_nucleus_morphology4.23741526
3MP0003693_abnormal_embryo_hatching4.23175021
4MP0008057_abnormal_DNA_replication4.10375889
5MP0003077_abnormal_cell_cycle3.73971321
6MP0004957_abnormal_blastocyst_morpholog3.49546067
7MP0002396_abnormal_hematopoietic_system2.87548629
8MP0008058_abnormal_DNA_repair2.74726644
9MP0008007_abnormal_cellular_replicative2.71290204
10MP0008932_abnormal_embryonic_tissue2.22688085
11MP0010307_abnormal_tumor_latency2.21880081
12MP0006054_spinal_hemorrhage2.20759079
13MP0004808_abnormal_hematopoietic_stem2.11846725
14MP0000350_abnormal_cell_proliferation2.06989325
15MP0010352_gastrointestinal_tract_polyps1.98630200
16MP0000490_abnormal_crypts_of1.96943398
17MP0003763_abnormal_thymus_physiology1.90172776
18MP0001730_embryonic_growth_arrest1.89255193
19MP0009333_abnormal_splenocyte_physiolog1.75875327
20MP0002398_abnormal_bone_marrow1.75649019
21MP0004185_abnormal_adipocyte_glucose1.74763183
22MP0002019_abnormal_tumor_incidence1.74713384
23MP0005076_abnormal_cell_differentiation1.71488168
24MP0000685_abnormal_immune_system1.70247907
25MP0000703_abnormal_thymus_morphology1.65711355
26MP0005257_abnormal_intraocular_pressure1.60108522
27MP0005451_abnormal_body_composition1.59998079
28MP0003806_abnormal_nucleotide_metabolis1.56302927
29MP0002722_abnormal_immune_system1.54612704
30MP0005623_abnormal_meninges_morphology1.53112802
31MP0010234_abnormal_vibrissa_follicle1.52069384
32MP0000689_abnormal_spleen_morphology1.50127589
33MP0004233_abnormal_muscle_weight1.47419529
34MP0001835_abnormal_antigen_presentation1.45494466
35MP0003123_paternal_imprinting1.45099406
36MP0000313_abnormal_cell_death1.44577206
37MP0003705_abnormal_hypodermis_morpholog1.44357704
38MP0003786_premature_aging1.43254341
39MP0001697_abnormal_embryo_size1.39815860
40MP0001545_abnormal_hematopoietic_system1.37948893
41MP0005397_hematopoietic_system_phenotyp1.37948893
42MP0010030_abnormal_orbit_morphology1.35768121
43MP0005671_abnormal_response_to1.35025448
44MP0002080_prenatal_lethality1.33771426
45MP0000858_altered_metastatic_potential1.32960713
46MP0001800_abnormal_humoral_immune1.32076500
47MP0002429_abnormal_blood_cell1.31026440
48MP0005380_embryogenesis_phenotype1.27742890
49MP0001672_abnormal_embryogenesis/_devel1.27742890
50MP0002060_abnormal_skin_morphology1.26805355
51MP0002166_altered_tumor_susceptibility1.26103425
52MP0003656_abnormal_erythrocyte_physiolo1.25608761
53MP0004197_abnormal_fetal_growth/weight/1.24910493
54MP0002420_abnormal_adaptive_immunity1.22833806
55MP0000716_abnormal_immune_system1.22015484
56MP0003984_embryonic_growth_retardation1.21254812
57MP0001819_abnormal_immune_cell1.21078763
58MP0001348_abnormal_lacrimal_gland1.20100197
59MP0002452_abnormal_antigen_presenting1.19634497
60MP0001346_abnormal_lacrimal_gland1.17515099
61MP0002088_abnormal_embryonic_growth/wei1.17100615
62MP0009697_abnormal_copulation1.17020587
63MP0001849_ear_inflammation1.16962672
64MP0003950_abnormal_plasma_membrane1.16746238
65MP0002405_respiratory_system_inflammati1.14699852
66MP0002796_impaired_skin_barrier1.14108103
67MP0009278_abnormal_bone_marrow1.14043930
68MP0002086_abnormal_extraembryonic_tissu1.08254403
69MP0002085_abnormal_embryonic_tissue1.07443223
70MP0000003_abnormal_adipose_tissue1.06511914
71MP0005023_abnormal_wound_healing1.04956729
72MP0003453_abnormal_keratinocyte_physiol1.04132433
73MP0008260_abnormal_autophagy1.03947509
74MP0008877_abnormal_DNA_methylation1.01594049
75MP0002006_tumorigenesis1.01223760
76MP0003436_decreased_susceptibility_to0.98622960
77MP0003091_abnormal_cell_migration0.98605623
78MP0002723_abnormal_immune_serum0.98440962
79MP0005000_abnormal_immune_tolerance0.97676186
80MP0002877_abnormal_melanocyte_morpholog0.97028791
81MP0003300_gastrointestinal_ulcer0.96921122
82MP0004147_increased_porphyrin_level0.92990369
83MP0003567_abnormal_fetal_cardiomyocyte0.91496018
84MP0009785_altered_susceptibility_to0.91345884
85MP0005387_immune_system_phenotype0.91236598
86MP0001790_abnormal_immune_system0.91236598
87MP0008438_abnormal_cutaneous_collagen0.90238026
88MP0003566_abnormal_cell_adhesion0.89957637
89MP0001216_abnormal_epidermal_layer0.89851926
90MP0000733_abnormal_muscle_development0.87874210
91MP0002084_abnormal_developmental_patter0.87466300
92MP0002009_preneoplasia0.86640673
93MP0003315_abnormal_perineum_morphology0.85790141
94MP0005025_abnormal_response_to0.84984598
95MP0003121_genomic_imprinting0.84760343
96MP0003279_aneurysm0.84283534
97MP0004272_abnormal_basement_membrane0.84192638
98MP0003221_abnormal_cardiomyocyte_apopto0.83462405
99MP0003448_altered_tumor_morphology0.81242663
100MP0001243_abnormal_dermal_layer0.79267330
101MP0003303_peritoneal_inflammation0.79218086
102MP0000015_abnormal_ear_pigmentation0.78874008
103MP0010155_abnormal_intestine_physiology0.76004623
104MP0001661_extended_life_span0.75550647
105MP0001873_stomach_inflammation0.73351167
106MP0002095_abnormal_skin_pigmentation0.73066845
107MP0005621_abnormal_cell_physiology0.72540888
108MP0005058_abnormal_lysosome_morphology0.72201750
109MP0002210_abnormal_sex_determination0.72045760
110MP0000477_abnormal_intestine_morphology0.70746387
111MP0004947_skin_inflammation0.70174629
112MP0000627_abnormal_mammary_gland0.69703041
113MP0001915_intracranial_hemorrhage0.69327386
114MP0003115_abnormal_respiratory_system0.68918590
115MP0000465_gastrointestinal_hemorrhage0.68789018
116MP0001881_abnormal_mammary_gland0.68738148
117MP0001853_heart_inflammation0.68553115
118MP0005384_cellular_phenotype0.67578493
119MP0003943_abnormal_hepatobiliary_system0.67385505
120MP0002163_abnormal_gland_morphology0.66818192
121MP0003941_abnormal_skin_development0.66174722
122MP0003191_abnormal_cellular_cholesterol0.65459775
123MP0006035_abnormal_mitochondrial_morpho0.64501503
124MP0001119_abnormal_female_reproductive0.64497434
125MP0009672_abnormal_birth_weight0.63988163
126MP0009053_abnormal_anal_canal0.62652551
127MP0005501_abnormal_skin_physiology0.62445151
128MP0003718_maternal_effect0.61521197
129MP0002970_abnormal_white_adipose0.61456186
130MP0002160_abnormal_reproductive_system0.61384120
131MP0000537_abnormal_urethra_morphology0.60364875
132MP0001145_abnormal_male_reproductive0.60363846
133MP0005408_hypopigmentation0.59955468
134MP0002933_joint_inflammation0.59899818
135MP0001186_pigmentation_phenotype0.59419984
136MP0009931_abnormal_skin_appearance0.58591705
137MP0000358_abnormal_cell_content/0.58208549
138MP0001727_abnormal_embryo_implantation0.58029807
139MP0005171_absent_coat_pigmentation0.56298116
140MP0000759_abnormal_skeletal_muscle0.54721342

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.95783352
2Chromsome breakage (HP:0040012)4.94389718
3Reticulocytopenia (HP:0001896)4.34732285
4Birth length less than 3rd percentile (HP:0003561)4.11881628
5Abnormality of chromosome stability (HP:0003220)3.78776420
6Abnormal number of erythroid precursors (HP:0012131)3.47180140
7Meckel diverticulum (HP:0002245)3.40374843
8Abnormality of cells of the erythroid lineage (HP:0012130)3.38004984
9Aplasia/Hypoplasia of the uvula (HP:0010293)3.36436747
10Abnormality of the preputium (HP:0100587)3.31494812
11Abnormality of the ileum (HP:0001549)3.28034579
12Premature rupture of membranes (HP:0001788)3.05017662
13Selective tooth agenesis (HP:0001592)2.93035072
14Colon cancer (HP:0003003)2.88415689
15Short 4th metacarpal (HP:0010044)2.86281755
16Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.86281755
17Patellar aplasia (HP:0006443)2.85403097
18Duodenal stenosis (HP:0100867)2.85058240
19Small intestinal stenosis (HP:0012848)2.85058240
20Slender long bone (HP:0003100)2.78105112
21Abnormality of the carotid arteries (HP:0005344)2.74095981
22Breast hypoplasia (HP:0003187)2.68898016
23High pitched voice (HP:0001620)2.67037143
24IgM deficiency (HP:0002850)2.66475118
25Aplasia/Hypoplasia of the patella (HP:0006498)2.65619052
26Ectopic kidney (HP:0000086)2.65474846
27Progressive muscle weakness (HP:0003323)2.61078679
28Microvesicular hepatic steatosis (HP:0001414)2.59089685
29Myelodysplasia (HP:0002863)2.57391114
3011 pairs of ribs (HP:0000878)2.55738632
31Increased nuchal translucency (HP:0010880)2.55680284
32Oral leukoplakia (HP:0002745)2.52647528
33Duplicated collecting system (HP:0000081)2.51892367
34Poikiloderma (HP:0001029)2.51479093
35Abnormality of the anterior horn cell (HP:0006802)2.50461633
36Degeneration of anterior horn cells (HP:0002398)2.50461633
37Hyperacusis (HP:0010780)2.49757156
38Absent thumb (HP:0009777)2.48010726
39Clubbing of toes (HP:0100760)2.46748618
40Abnormality of reticulocytes (HP:0004312)2.46616930
41Entropion (HP:0000621)2.46453336
42Microretrognathia (HP:0000308)2.42306167
43Bone marrow hypocellularity (HP:0005528)2.40769451
44Hypoplasia of the capital femoral epiphysis (HP:0003090)2.39839958
45Insomnia (HP:0100785)2.39277077
46Pallor (HP:0000980)2.39164861
47Achilles tendon contracture (HP:0001771)2.38778170
48Basal cell carcinoma (HP:0002671)2.37285611
49Abnormality of the umbilical cord (HP:0010881)2.36793096
50Abnormal number of incisors (HP:0011064)2.35512179
51Aplastic anemia (HP:0001915)2.35284995
52Abnormality of the heme biosynthetic pathway (HP:0010472)2.34807643
53Osteolytic defects of the phalanges of the hand (HP:0009771)2.33406502
54Osteolytic defects of the hand bones (HP:0009699)2.33406502
55Ulnar bowing (HP:0003031)2.33334217
56Trismus (HP:0000211)2.32663291
57Vertebral compression fractures (HP:0002953)2.31922675
58Thrombocytosis (HP:0001894)2.31375110
59B lymphocytopenia (HP:0010976)2.30103953
60Abnormality of B cell number (HP:0010975)2.30103953
61Abnormality of the duodenum (HP:0002246)2.27863553
62Medulloblastoma (HP:0002885)2.27462964
63Cafe-au-lait spot (HP:0000957)2.25111884
64Abnormal gallbladder physiology (HP:0012438)2.21427847
65Cholecystitis (HP:0001082)2.21427847
66Abnormality of the renal collecting system (HP:0004742)2.21114481
67Lymphoma (HP:0002665)2.20809486
68Recurrent viral infections (HP:0004429)2.19948282
69Single umbilical artery (HP:0001195)2.16150926
70Abnormality of the fetal cardiovascular system (HP:0010948)2.16150926
71Abnormal umbilical cord blood vessels (HP:0011403)2.16150926
72Abnormality of T cells (HP:0002843)2.15619171
73Neoplasm of the pancreas (HP:0002894)2.14227933
74Abnormality of T cell physiology (HP:0011840)2.12329601
75Combined immunodeficiency (HP:0005387)2.12176864
76Papilledema (HP:0001085)2.10382524
77Microglossia (HP:0000171)2.10216435
78Cellulitis (HP:0100658)2.07792021
79Distal lower limb amyotrophy (HP:0008944)2.07419103
80Abnormality of the calcaneus (HP:0008364)2.06717187
81Macrocytic anemia (HP:0001972)2.06625620
82T lymphocytopenia (HP:0005403)2.06217083
83Flared metaphyses (HP:0003015)2.05026681
84Deep philtrum (HP:0002002)2.04348864
85Short thumb (HP:0009778)2.02580367
86Rough bone trabeculation (HP:0100670)2.02500404
87Abnormality of pyrimidine metabolism (HP:0004353)2.02449294
88Tracheoesophageal fistula (HP:0002575)2.01601853
89Proximal placement of thumb (HP:0009623)2.01304622
90Recurrent bronchitis (HP:0002837)2.00832957
91Agnosia (HP:0010524)2.00555717
92Broad distal phalanx of finger (HP:0009836)2.00237043
93Abnormality of the Achilles tendon (HP:0005109)1.99698516
94Elbow flexion contracture (HP:0002987)1.98319644
95Abnormality of chromosome segregation (HP:0002916)1.98276980
96Deviation of the thumb (HP:0009603)1.98246061
97Ankyloglossia (HP:0010296)1.97630515
98Triphalangeal thumb (HP:0001199)1.97358348
99Elevated erythrocyte sedimentation rate (HP:0003565)1.96856460
100Sloping forehead (HP:0000340)1.96618714
101Poikilocytosis (HP:0004447)1.95849131
102Premature graying of hair (HP:0002216)1.92403323
103Abnormality of T cell number (HP:0011839)1.92355071
104Orthostatic hypotension (HP:0001278)1.91215481
105Atresia of the external auditory canal (HP:0000413)1.90564217
106Abnormality of oral frenula (HP:0000190)1.90450599
107Slender build (HP:0001533)1.89585947
108Severe combined immunodeficiency (HP:0004430)1.89332723
109Biconcave vertebral bodies (HP:0004586)1.88135485
110Broad face (HP:0000283)1.87535931
111Aplasia/Hypoplasia of the thymus (HP:0010515)1.87472328
112Progressive external ophthalmoplegia (HP:0000590)1.85846993
113Increased connective tissue (HP:0009025)1.85300816
114Overlapping toe (HP:0001845)1.84926441
115Multiple enchondromatosis (HP:0005701)1.84109143
116Abnormality of the 4th metacarpal (HP:0010012)1.84020872
117Broad palm (HP:0001169)1.83923694
118Abnormality of the distal phalanges of the toes (HP:0010182)1.83059070
119Abnormality of DNA repair (HP:0003254)1.82906668
120Leukopenia (HP:0001882)1.82530698
121Ragged-red muscle fibers (HP:0003200)1.81948204
122Short nail (HP:0001799)1.81467844
123Cortical dysplasia (HP:0002539)1.81241315
124Increased density of long bones (HP:0006392)1.81211168
125IgA deficiency (HP:0002720)1.80901221
126Long palpebral fissure (HP:0000637)1.79949712
127Hypergonadotropic hypogonadism (HP:0000815)1.79788667
128Absent radius (HP:0003974)1.79656915
129Reduced subcutaneous adipose tissue (HP:0003758)1.78675775
130Volvulus (HP:0002580)1.78236440
131Prominent metopic ridge (HP:0005487)1.77629349
132Ureteral duplication (HP:0000073)1.77343984
133Ependymoma (HP:0002888)1.77238108
134Aplasia/Hypoplasia of the sacrum (HP:0008517)1.77163763
135Fatigue (HP:0012378)1.77077635
136IgG deficiency (HP:0004315)1.76685264
137Squamous cell carcinoma (HP:0002860)1.76260061
138Protrusio acetabuli (HP:0003179)1.74903983
139Nonimmune hydrops fetalis (HP:0001790)1.74711015
140Generalized amyotrophy (HP:0003700)1.74160808
141Ankle contracture (HP:0006466)1.73426700
142Spinal rigidity (HP:0003306)1.72502940
143Prominent nose (HP:0000448)1.70283134
144Chronic otitis media (HP:0000389)1.69920803
145Secondary amenorrhea (HP:0000869)1.68832210
146Centrally nucleated skeletal muscle fibers (HP:0003687)1.68586460
147Asymmetry of the thorax (HP:0001555)1.65617958
148Duplication of thumb phalanx (HP:0009942)1.65198706
149Flattened epiphyses (HP:0003071)1.64861440
150Cutaneous melanoma (HP:0012056)1.62196892
151Arteriovenous malformation (HP:0100026)1.61999662
152Abnormality of glycolysis (HP:0004366)1.59788106
153Long eyelashes (HP:0000527)1.59700569
154Nephroblastoma (Wilms tumor) (HP:0002667)1.58685733
155Disproportionate tall stature (HP:0001519)1.58422735
156Missing ribs (HP:0000921)1.58190881
157Progressive hearing impairment (HP:0001730)1.58144061
158Abnormalities of placenta or umbilical cord (HP:0001194)1.57102328
159Choanal atresia (HP:0000453)1.55946381
160Abnormality of the phalanges of the hallux (HP:0010057)1.55666248
161Patellar dislocation (HP:0002999)1.55574823
162Abnormal foot bone ossification (HP:0010675)1.55367369
163Overriding aorta (HP:0002623)1.55084027

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.33724375
2WEE14.04648734
3CCNB13.48381896
4BUB13.23351519
5NEK23.20453628
6SMG13.11269155
7PASK2.66383318
8IRAK32.42570171
9VRK22.42438236
10NEK12.35100660
11PRPF4B2.29915839
12EIF2AK12.29357778
13BRSK12.22863765
14MAP3K102.21719912
15BRSK22.19737901
16TLK12.18313424
17TESK22.13807871
18NME22.09761591
19MAP4K12.07438904
20ACVR1B1.92307889
21ICK1.92098760
22PBK1.89886250
23STK41.84131544
24RPS6KA41.77883279
25VRK11.75957201
26TRIB31.73822429
27AURKB1.72237557
28PLK11.66603609
29STK101.64078722
30SCYL21.55916019
31EEF2K1.53885574
32ATR1.53534618
33MST1R1.47566265
34EPHA21.45601562
35CDK41.41175731
36MAP3K81.39617393
37CLK11.39014383
38CDK71.38860776
39PKN21.38719756
40TTK1.37694152
41TESK11.33010875
42SRPK11.27287014
43LRRK21.25702073
44ARAF1.15707705
45CHEK21.10408124
46DYRK31.10022403
47BLK1.09649774
48AURKA1.07476979
49TAF11.03499169
50PAK41.03496704
51TGFBR10.98900151
52PLK40.96531432
53SIK10.95667701
54KDR0.95185332
55ZAP700.91431610
56NEK90.89582762
57GRK60.89066537
58CHEK10.87628393
59MAP2K30.87162536
60PIM10.86638169
61CDK60.84039766
62CDK120.79462643
63CSF1R0.78526751
64RPS6KB20.77835697
65MKNK10.77262958
66PDGFRA0.75787425
67LIMK10.74873712
68BTK0.73208732
69PLK30.71417762
70MET0.71252009
71MELK0.70110811
72CDK80.70076012
73EIF2AK30.69115270
74PTK20.68749622
75MTOR0.67318599
76ZAK0.67110871
77FLT30.64589552
78TYK20.64405139
79KSR20.64129044
80PIM20.63747161
81TTN0.63305998
82ERBB40.62652566
83ATM0.62110931
84CDK20.59951162
85MOS0.58286651
86SYK0.57600357
87KIT0.55594906
88RPS6KA50.54546443
89CDK90.53639652
90MAP3K130.52341078
91RAF10.51423580
92ERN10.50708777
93MAPK110.50138074
94DAPK10.49581285
95MAP3K110.49439417
96DYRK1B0.48440122
97AKT20.48062732
98PAK20.47770407
99JAK30.47751190
100CDK10.47352749
101CDK11A0.47279413
102CDK150.46949145
103LATS20.46441860
104IRAK20.45728083
105CDK180.45716119
106PAK10.45692656
107TEC0.44816981
108STK160.44128401
109LYN0.43484807
110ITK0.42774827
111CSNK2A10.41984996
112TSSK60.41491400
113ILK0.40217293
114LMTK20.36842625
115TAOK20.36269615
116IRAK40.35117850
117BMX0.35114649
118TBK10.34933698
119CDK140.34840967
120MAP3K140.33039724
121MAPKAPK20.32959926
122ALK0.32782236
123BCKDK0.31966254
124EIF2AK20.31912480
125TRPM70.31797683
126ABL20.31430783
127UHMK10.25859807
128PRKCI0.25787711
129CSNK2A20.25262373
130BRD40.24779788
131MARK30.24416999
132LCK0.24306482
133PTK60.23813147
134BRAF0.23670742

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030306.80341630
2Mismatch repair_Homo sapiens_hsa034305.18777591
3Base excision repair_Homo sapiens_hsa034103.91835344
4Homologous recombination_Homo sapiens_hsa034403.68987672
5Cell cycle_Homo sapiens_hsa041103.27451436
6Nucleotide excision repair_Homo sapiens_hsa034203.16772111
7Fanconi anemia pathway_Homo sapiens_hsa034602.71266443
8Spliceosome_Homo sapiens_hsa030402.53751244
9One carbon pool by folate_Homo sapiens_hsa006702.35575233
10Ribosome_Homo sapiens_hsa030102.34339999
11Non-homologous end-joining_Homo sapiens_hsa034502.28415396
12Pyrimidine metabolism_Homo sapiens_hsa002402.16322807
13Systemic lupus erythematosus_Homo sapiens_hsa053222.01646038
14p53 signaling pathway_Homo sapiens_hsa041151.93589954
15RNA transport_Homo sapiens_hsa030131.92207232
16Proteasome_Homo sapiens_hsa030501.83452126
17Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.70901732
18Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.59909535
19Primary immunodeficiency_Homo sapiens_hsa053401.51380318
20Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.38387931
21RNA polymerase_Homo sapiens_hsa030201.37530408
22Viral carcinogenesis_Homo sapiens_hsa052031.27925225
23Central carbon metabolism in cancer_Homo sapiens_hsa052301.16592387
242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.15729823
25mRNA surveillance pathway_Homo sapiens_hsa030151.15591623
26Carbon metabolism_Homo sapiens_hsa012001.11398691
27Herpes simplex infection_Homo sapiens_hsa051681.10748104
28Antigen processing and presentation_Homo sapiens_hsa046121.09533676
29HTLV-I infection_Homo sapiens_hsa051661.09164613
30RNA degradation_Homo sapiens_hsa030181.06690816
31Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.04254900
32Small cell lung cancer_Homo sapiens_hsa052221.02328470
33Epstein-Barr virus infection_Homo sapiens_hsa051691.00630286
34Alcoholism_Homo sapiens_hsa050340.96556373
35Fructose and mannose metabolism_Homo sapiens_hsa000510.95146055
36Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.91286960
37Purine metabolism_Homo sapiens_hsa002300.87747051
38Oocyte meiosis_Homo sapiens_hsa041140.85425811
39MicroRNAs in cancer_Homo sapiens_hsa052060.85200610
40Hepatitis B_Homo sapiens_hsa051610.84829163
41Galactose metabolism_Homo sapiens_hsa000520.84763611
42Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.84703807
43Measles_Homo sapiens_hsa051620.84695427
44Shigellosis_Homo sapiens_hsa051310.79454068
45Apoptosis_Homo sapiens_hsa042100.78268544
46Bladder cancer_Homo sapiens_hsa052190.76877078
47Chronic myeloid leukemia_Homo sapiens_hsa052200.76312194
48Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.73168554
49Basal transcription factors_Homo sapiens_hsa030220.71073902
50Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.70682247
51Pancreatic cancer_Homo sapiens_hsa052120.70562736
52Glioma_Homo sapiens_hsa052140.67960871
53NF-kappa B signaling pathway_Homo sapiens_hsa040640.67826447
54Intestinal immune network for IgA production_Homo sapiens_hsa046720.66691227
55Legionellosis_Homo sapiens_hsa051340.66426842
56N-Glycan biosynthesis_Homo sapiens_hsa005100.66011521
57Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.65249749
58Hematopoietic cell lineage_Homo sapiens_hsa046400.64590659
59Viral myocarditis_Homo sapiens_hsa054160.63558312
60Transcriptional misregulation in cancer_Homo sapiens_hsa052020.62732719
61B cell receptor signaling pathway_Homo sapiens_hsa046620.61964507
62Pyruvate metabolism_Homo sapiens_hsa006200.61433338
63Drug metabolism - other enzymes_Homo sapiens_hsa009830.60782896
64Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.59044100
65Leishmaniasis_Homo sapiens_hsa051400.58368672
66Cysteine and methionine metabolism_Homo sapiens_hsa002700.57172464
67Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.54810714
68Non-small cell lung cancer_Homo sapiens_hsa052230.54301229
69Endometrial cancer_Homo sapiens_hsa052130.54138963
70Colorectal cancer_Homo sapiens_hsa052100.52790687
71Melanoma_Homo sapiens_hsa052180.52520636
72Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.50678629
73Fatty acid elongation_Homo sapiens_hsa000620.50539332
74Vitamin B6 metabolism_Homo sapiens_hsa007500.50320501
75Cyanoamino acid metabolism_Homo sapiens_hsa004600.49631357
76Renal cell carcinoma_Homo sapiens_hsa052110.49222582
77Folate biosynthesis_Homo sapiens_hsa007900.48758597
78T cell receptor signaling pathway_Homo sapiens_hsa046600.48201120
79Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.48030549
80Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.47415629
81Other glycan degradation_Homo sapiens_hsa005110.47072857
82Thyroid cancer_Homo sapiens_hsa052160.46446662
83Pentose phosphate pathway_Homo sapiens_hsa000300.45308530
84Leukocyte transendothelial migration_Homo sapiens_hsa046700.44720115
85Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.44263222
86Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.42536245
87Focal adhesion_Homo sapiens_hsa045100.41971336
88Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.40586490
89Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.38822722
90Influenza A_Homo sapiens_hsa051640.37876057
91Selenocompound metabolism_Homo sapiens_hsa004500.36465945
92Thyroid hormone signaling pathway_Homo sapiens_hsa049190.35869499
93Prostate cancer_Homo sapiens_hsa052150.35719546
94Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.34317768
95Glutathione metabolism_Homo sapiens_hsa004800.31555492
96Toxoplasmosis_Homo sapiens_hsa051450.29976286
97Protein export_Homo sapiens_hsa030600.29519542
98Prion diseases_Homo sapiens_hsa050200.29155668
99Pathways in cancer_Homo sapiens_hsa052000.28799393
100Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.28696669
101Acute myeloid leukemia_Homo sapiens_hsa052210.28321542
102Biosynthesis of amino acids_Homo sapiens_hsa012300.27276176
103Platelet activation_Homo sapiens_hsa046110.27079294
104Jak-STAT signaling pathway_Homo sapiens_hsa046300.27071306
105Hippo signaling pathway_Homo sapiens_hsa043900.26422119
106Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.26183347
107Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.25696266
108Proteoglycans in cancer_Homo sapiens_hsa052050.24944521
109Vibrio cholerae infection_Homo sapiens_hsa051100.24167316
110Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.24043763
111Regulation of actin cytoskeleton_Homo sapiens_hsa048100.23984780
112Sulfur relay system_Homo sapiens_hsa041220.23503089
113Pertussis_Homo sapiens_hsa051330.23025168
114Notch signaling pathway_Homo sapiens_hsa043300.23003368
115RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.22588090
116AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.22545861
117Adherens junction_Homo sapiens_hsa045200.21827890
118mTOR signaling pathway_Homo sapiens_hsa041500.21603502
119Asthma_Homo sapiens_hsa053100.21027725
120Allograft rejection_Homo sapiens_hsa053300.20015682
121Osteoclast differentiation_Homo sapiens_hsa043800.19524193
122Basal cell carcinoma_Homo sapiens_hsa052170.19404209
123Lysine degradation_Homo sapiens_hsa003100.18373820
124Neurotrophin signaling pathway_Homo sapiens_hsa047220.17931619
125TGF-beta signaling pathway_Homo sapiens_hsa043500.16574230
126Glycosaminoglycan degradation_Homo sapiens_hsa005310.15832881
127Salmonella infection_Homo sapiens_hsa051320.15623700
128VEGF signaling pathway_Homo sapiens_hsa043700.15434529
129HIF-1 signaling pathway_Homo sapiens_hsa040660.14977211

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