

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of action potential (GO:0045760) | 8.16635415 |
| 2 | fusion of sperm to egg plasma membrane (GO:0007342) | 7.06275231 |
| 3 | regulation of acrosome reaction (GO:0060046) | 6.48911760 |
| 4 | plasma membrane fusion (GO:0045026) | 5.54976441 |
| 5 | DNA deamination (GO:0045006) | 5.45785791 |
| 6 | regulation of action potential (GO:0098900) | 5.31638448 |
| 7 | regulation of cell communication by electrical coupling (GO:0010649) | 5.11263356 |
| 8 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 5.09195151 |
| 9 | maturation of 5.8S rRNA (GO:0000460) | 4.96856187 |
| 10 | proteasome assembly (GO:0043248) | 4.49316367 |
| 11 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.42369623 |
| 12 | piRNA metabolic process (GO:0034587) | 4.26265418 |
| 13 | ubiquinone metabolic process (GO:0006743) | 4.26249237 |
| 14 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 4.12885721 |
| 15 | rRNA modification (GO:0000154) | 4.12775831 |
| 16 | protein-cofactor linkage (GO:0018065) | 4.03647016 |
| 17 | neuronal action potential (GO:0019228) | 4.01598107 |
| 18 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.82758148 |
| 19 | kynurenine metabolic process (GO:0070189) | 3.79986437 |
| 20 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.76531445 |
| 21 | mitochondrial RNA metabolic process (GO:0000959) | 3.72272545 |
| 22 | positive regulation of protein targeting to membrane (GO:0090314) | 3.71554839 |
| 23 | protein deneddylation (GO:0000338) | 3.70372996 |
| 24 | cullin deneddylation (GO:0010388) | 3.67644055 |
| 25 | sperm-egg recognition (GO:0035036) | 3.63927867 |
| 26 | protein polyglutamylation (GO:0018095) | 3.62476121 |
| 27 | binding of sperm to zona pellucida (GO:0007339) | 3.60713605 |
| 28 | ubiquinone biosynthetic process (GO:0006744) | 3.54302848 |
| 29 | tryptophan catabolic process (GO:0006569) | 3.52393441 |
| 30 | indole-containing compound catabolic process (GO:0042436) | 3.52393441 |
| 31 | indolalkylamine catabolic process (GO:0046218) | 3.52393441 |
| 32 | rRNA methylation (GO:0031167) | 3.48101609 |
| 33 | primary amino compound metabolic process (GO:1901160) | 3.47549149 |
| 34 | pseudouridine synthesis (GO:0001522) | 3.36779803 |
| 35 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.36451529 |
| 36 | DNA double-strand break processing (GO:0000729) | 3.35678330 |
| 37 | serotonin metabolic process (GO:0042428) | 3.35602328 |
| 38 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.33828247 |
| 39 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.33828247 |
| 40 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.33452405 |
| 41 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.32238821 |
| 42 | cellular ketone body metabolic process (GO:0046950) | 3.28770534 |
| 43 | cell-cell recognition (GO:0009988) | 3.27559907 |
| 44 | behavioral response to nicotine (GO:0035095) | 3.26331089 |
| 45 | tryptophan metabolic process (GO:0006568) | 3.18812061 |
| 46 | termination of RNA polymerase III transcription (GO:0006386) | 3.16275030 |
| 47 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.16275030 |
| 48 | chaperone-mediated protein transport (GO:0072321) | 3.11254263 |
| 49 | indole-containing compound metabolic process (GO:0042430) | 3.09207566 |
| 50 | magnesium ion transport (GO:0015693) | 3.07864360 |
| 51 | cytidine catabolic process (GO:0006216) | 3.07463565 |
| 52 | cytidine deamination (GO:0009972) | 3.07463565 |
| 53 | cytidine metabolic process (GO:0046087) | 3.07463565 |
| 54 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.05710627 |
| 55 | protein complex biogenesis (GO:0070271) | 2.98336278 |
| 56 | neuron cell-cell adhesion (GO:0007158) | 2.97812130 |
| 57 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.94463064 |
| 58 | ATP synthesis coupled proton transport (GO:0015986) | 2.94378891 |
| 59 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.94378891 |
| 60 | DNA methylation involved in gamete generation (GO:0043046) | 2.94260315 |
| 61 | regulation of cilium movement (GO:0003352) | 2.89891612 |
| 62 | ketone body metabolic process (GO:1902224) | 2.88136583 |
| 63 | histone H4-K12 acetylation (GO:0043983) | 2.88007372 |
| 64 | quinone biosynthetic process (GO:1901663) | 2.87820383 |
| 65 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.86166062 |
| 66 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.83946920 |
| 67 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.83041967 |
| 68 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.83041967 |
| 69 | NADH dehydrogenase complex assembly (GO:0010257) | 2.83041967 |
| 70 | peptidyl-histidine modification (GO:0018202) | 2.82687457 |
| 71 | carnitine metabolic process (GO:0009437) | 2.81469134 |
| 72 | indolalkylamine metabolic process (GO:0006586) | 2.78691072 |
| 73 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.76810439 |
| 74 | tRNA processing (GO:0008033) | 2.76482736 |
| 75 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.75275669 |
| 76 | ribosome assembly (GO:0042255) | 2.74188222 |
| 77 | fucose catabolic process (GO:0019317) | 2.73861284 |
| 78 | L-fucose metabolic process (GO:0042354) | 2.73861284 |
| 79 | L-fucose catabolic process (GO:0042355) | 2.73861284 |
| 80 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.71470911 |
| 81 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.68810238 |
| 82 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 2.68022222 |
| 83 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.67648275 |
| 84 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.65315805 |
| 85 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.63470854 |
| 86 | negative regulation of ligase activity (GO:0051352) | 2.61765311 |
| 87 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.61765311 |
| 88 | behavioral response to ethanol (GO:0048149) | 2.61665494 |
| 89 | termination of RNA polymerase I transcription (GO:0006363) | 2.61445337 |
| 90 | sequestering of extracellular ligand from receptor (GO:0035581) | 2.60532376 |
| 91 | protein peptidyl-prolyl isomerization (GO:0000413) | 2.59703172 |
| 92 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.59204168 |
| 93 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.59080473 |
| 94 | CENP-A containing nucleosome assembly (GO:0034080) | 2.58782050 |
| 95 | tRNA modification (GO:0006400) | 2.58101581 |
| 96 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.57861132 |
| 97 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.57861132 |
| 98 | tRNA metabolic process (GO:0006399) | 2.57628074 |
| 99 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.56624390 |
| 100 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.56624390 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 5.08471855 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.61284910 |
| 3 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.35595135 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.22732420 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.11916550 |
| 6 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.86628221 |
| 7 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.81164292 |
| 8 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.80966825 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.72575504 |
| 10 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.64728411 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.63300418 |
| 12 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.55624487 |
| 13 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.41574558 |
| 14 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.28712788 |
| 15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.25424069 |
| 16 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.22438127 |
| 17 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.16946513 |
| 18 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.14828232 |
| 19 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.11975730 |
| 20 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.08568362 |
| 21 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.03892619 |
| 22 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.02527418 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.91982798 |
| 24 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.88095171 |
| 25 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.85187625 |
| 26 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.83549066 |
| 27 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.82557664 |
| 28 | FUS_26573619_Chip-Seq_HEK293_Human | 1.81370924 |
| 29 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.77028025 |
| 30 | P300_19829295_ChIP-Seq_ESCs_Human | 1.69725465 |
| 31 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.66773326 |
| 32 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.64331240 |
| 33 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.64040284 |
| 34 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.54440368 |
| 35 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.53873421 |
| 36 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.49852837 |
| 37 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.48818403 |
| 38 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.48267935 |
| 39 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.42722718 |
| 40 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.42502762 |
| 41 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.39915585 |
| 42 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.39695367 |
| 43 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.35869700 |
| 44 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.35003504 |
| 45 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.29281039 |
| 46 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.28300826 |
| 47 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.26283988 |
| 48 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.25033643 |
| 49 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.24389055 |
| 50 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.22169575 |
| 51 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.22169575 |
| 52 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.21704085 |
| 53 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.19986322 |
| 54 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.17506015 |
| 55 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.17233127 |
| 56 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.17233127 |
| 57 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.15800258 |
| 58 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.15746806 |
| 59 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.15746806 |
| 60 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.14383546 |
| 61 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.13163580 |
| 62 | NCOR_22424771_ChIP-Seq_293T_Human | 1.11050769 |
| 63 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.10568702 |
| 64 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.10407739 |
| 65 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.10171452 |
| 66 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.09359292 |
| 67 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.09238662 |
| 68 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.06167559 |
| 69 | TCF4_23295773_ChIP-Seq_U87_Human | 1.05503463 |
| 70 | AR_20517297_ChIP-Seq_VCAP_Human | 1.05303552 |
| 71 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.05228431 |
| 72 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.04511848 |
| 73 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.04479138 |
| 74 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.99990194 |
| 75 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.97148811 |
| 76 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.96939808 |
| 77 | AR_25329375_ChIP-Seq_VCAP_Human | 0.95634950 |
| 78 | STAT3_23295773_ChIP-Seq_U87_Human | 0.94725725 |
| 79 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.93061027 |
| 80 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.92646133 |
| 81 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.92482276 |
| 82 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.92390169 |
| 83 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.92350775 |
| 84 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.92304378 |
| 85 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.92224454 |
| 86 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92022907 |
| 87 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.91855502 |
| 88 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.91216568 |
| 89 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.90840009 |
| 90 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.90761471 |
| 91 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.90439424 |
| 92 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.90318067 |
| 93 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.89832672 |
| 94 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.89484101 |
| 95 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.89434554 |
| 96 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 0.88453701 |
| 97 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.87116824 |
| 98 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.87054676 |
| 99 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.87054676 |
| 100 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.85130980 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008877_abnormal_DNA_methylation | 3.32070390 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 3.28921409 |
| 3 | MP0000569_abnormal_digit_pigmentation | 3.07112159 |
| 4 | MP0003283_abnormal_digestive_organ | 2.91772699 |
| 5 | MP0009379_abnormal_foot_pigmentation | 2.87951091 |
| 6 | MP0005646_abnormal_pituitary_gland | 2.83005732 |
| 7 | MP0004133_heterotaxia | 2.36276499 |
| 8 | MP0001873_stomach_inflammation | 2.22043203 |
| 9 | MP0005084_abnormal_gallbladder_morpholo | 2.20709534 |
| 10 | MP0005085_abnormal_gallbladder_physiolo | 2.07477836 |
| 11 | MP0006292_abnormal_olfactory_placode | 2.03006824 |
| 12 | MP0002736_abnormal_nociception_after | 2.01006566 |
| 13 | MP0002102_abnormal_ear_morphology | 1.99153255 |
| 14 | MP0009745_abnormal_behavioral_response | 1.97736685 |
| 15 | MP0001188_hyperpigmentation | 1.95823612 |
| 16 | MP0002272_abnormal_nervous_system | 1.92189321 |
| 17 | MP0003646_muscle_fatigue | 1.90847502 |
| 18 | MP0005174_abnormal_tail_pigmentation | 1.89798053 |
| 19 | MP0001968_abnormal_touch/_nociception | 1.89631671 |
| 20 | MP0008058_abnormal_DNA_repair | 1.75828766 |
| 21 | MP0003806_abnormal_nucleotide_metabolis | 1.71271214 |
| 22 | MP0006036_abnormal_mitochondrial_physio | 1.69767919 |
| 23 | MP0000015_abnormal_ear_pigmentation | 1.66885237 |
| 24 | MP0003195_calcinosis | 1.65101450 |
| 25 | MP0003693_abnormal_embryo_hatching | 1.63933257 |
| 26 | MP0001501_abnormal_sleep_pattern | 1.58960742 |
| 27 | MP0002638_abnormal_pupillary_reflex | 1.57346496 |
| 28 | MP0008007_abnormal_cellular_replicative | 1.55736729 |
| 29 | MP0002064_seizures | 1.54535853 |
| 30 | MP0003787_abnormal_imprinting | 1.51045614 |
| 31 | MP0003786_premature_aging | 1.47085033 |
| 32 | MP0002837_dystrophic_cardiac_calcinosis | 1.44397384 |
| 33 | MP0006035_abnormal_mitochondrial_morpho | 1.40422064 |
| 34 | MP0005645_abnormal_hypothalamus_physiol | 1.39375617 |
| 35 | MP0002277_abnormal_respiratory_mucosa | 1.37887129 |
| 36 | MP0001986_abnormal_taste_sensitivity | 1.37227174 |
| 37 | MP0008872_abnormal_physiological_respon | 1.33438157 |
| 38 | MP0001486_abnormal_startle_reflex | 1.31366566 |
| 39 | MP0005365_abnormal_bile_salt | 1.30829023 |
| 40 | MP0005187_abnormal_penis_morphology | 1.29621220 |
| 41 | MP0009046_muscle_twitch | 1.29117154 |
| 42 | MP0002095_abnormal_skin_pigmentation | 1.23503766 |
| 43 | MP0004019_abnormal_vitamin_homeostasis | 1.23174947 |
| 44 | MP0004043_abnormal_pH_regulation | 1.23011579 |
| 45 | MP0003718_maternal_effect | 1.22674599 |
| 46 | MP0002733_abnormal_thermal_nociception | 1.19369211 |
| 47 | MP0004142_abnormal_muscle_tone | 1.19134191 |
| 48 | MP0002928_abnormal_bile_duct | 1.18537629 |
| 49 | MP0003137_abnormal_impulse_conducting | 1.17622554 |
| 50 | MP0008875_abnormal_xenobiotic_pharmacok | 1.16351563 |
| 51 | MP0001293_anophthalmia | 1.15640414 |
| 52 | MP0004147_increased_porphyrin_level | 1.15154065 |
| 53 | MP0001905_abnormal_dopamine_level | 1.13179996 |
| 54 | MP0002938_white_spotting | 1.12773698 |
| 55 | MP0004145_abnormal_muscle_electrophysio | 1.09541476 |
| 56 | MP0005551_abnormal_eye_electrophysiolog | 1.09234931 |
| 57 | MP0003880_abnormal_central_pattern | 1.08769653 |
| 58 | MP0000613_abnormal_salivary_gland | 1.08585516 |
| 59 | MP0009053_abnormal_anal_canal | 1.08093011 |
| 60 | MP0006276_abnormal_autonomic_nervous | 1.07714181 |
| 61 | MP0002234_abnormal_pharynx_morphology | 1.05680293 |
| 62 | MP0006072_abnormal_retinal_apoptosis | 1.05012868 |
| 63 | MP0002734_abnormal_mechanical_nocicepti | 1.04771588 |
| 64 | MP0005671_abnormal_response_to | 1.04181150 |
| 65 | MP0001970_abnormal_pain_threshold | 1.01481019 |
| 66 | MP0009785_altered_susceptibility_to | 1.01005422 |
| 67 | MP0003252_abnormal_bile_duct | 1.00773437 |
| 68 | MP0008961_abnormal_basal_metabolism | 1.00100135 |
| 69 | MP0008057_abnormal_DNA_replication | 0.99486704 |
| 70 | MP0005636_abnormal_mineral_homeostasis | 0.95217211 |
| 71 | MP0003119_abnormal_digestive_system | 0.94995249 |
| 72 | MP0001529_abnormal_vocalization | 0.92548929 |
| 73 | MP0002653_abnormal_ependyma_morphology | 0.92151372 |
| 74 | MP0002210_abnormal_sex_determination | 0.91707816 |
| 75 | MP0002876_abnormal_thyroid_physiology | 0.91458343 |
| 76 | MP0002006_tumorigenesis | 0.89603190 |
| 77 | MP0005389_reproductive_system_phenotype | 0.87924813 |
| 78 | MP0001765_abnormal_ion_homeostasis | 0.87171255 |
| 79 | MP0001929_abnormal_gametogenesis | 0.85138223 |
| 80 | MP0006054_spinal_hemorrhage | 0.83409362 |
| 81 | MP0002160_abnormal_reproductive_system | 0.82802387 |
| 82 | MP0004215_abnormal_myocardial_fiber | 0.82756913 |
| 83 | MP0008995_early_reproductive_senescence | 0.81968062 |
| 84 | MP0002751_abnormal_autonomic_nervous | 0.80858113 |
| 85 | MP0005332_abnormal_amino_acid | 0.80788333 |
| 86 | MP0001440_abnormal_grooming_behavior | 0.80330909 |
| 87 | MP0001919_abnormal_reproductive_system | 0.80167313 |
| 88 | MP0010094_abnormal_chromosome_stability | 0.79212694 |
| 89 | MP0000538_abnormal_urinary_bladder | 0.79194567 |
| 90 | MP0009643_abnormal_urine_homeostasis | 0.79131796 |
| 91 | MP0003698_abnormal_male_reproductive | 0.78734550 |
| 92 | MP0000653_abnormal_sex_gland | 0.76779313 |
| 93 | MP0004885_abnormal_endolymph | 0.76612626 |
| 94 | MP0002572_abnormal_emotion/affect_behav | 0.76186576 |
| 95 | MP0000685_abnormal_immune_system | 0.76014401 |
| 96 | MP0005423_abnormal_somatic_nervous | 0.75213997 |
| 97 | MP0000647_abnormal_sebaceous_gland | 0.73921703 |
| 98 | MP0002166_altered_tumor_susceptibility | 0.73709854 |
| 99 | MP0003011_delayed_dark_adaptation | 0.73574575 |
| 100 | MP0001485_abnormal_pinna_reflex | 0.73184965 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Pancreatic cysts (HP:0001737) | 4.83313008 |
| 2 | Abnormality of midbrain morphology (HP:0002418) | 3.95640636 |
| 3 | Molar tooth sign on MRI (HP:0002419) | 3.95640636 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 3.95589069 |
| 5 | Acute encephalopathy (HP:0006846) | 3.57828355 |
| 6 | Progressive inability to walk (HP:0002505) | 3.42383125 |
| 7 | Congenital, generalized hypertrichosis (HP:0004540) | 3.39489621 |
| 8 | Pancreatic fibrosis (HP:0100732) | 3.37771122 |
| 9 | Azoospermia (HP:0000027) | 3.34486967 |
| 10 | Progressive macrocephaly (HP:0004481) | 3.32979091 |
| 11 | Increased CSF lactate (HP:0002490) | 3.32804295 |
| 12 | True hermaphroditism (HP:0010459) | 3.30607433 |
| 13 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.17937912 |
| 14 | Absent/shortened dynein arms (HP:0200106) | 3.10686508 |
| 15 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.10686508 |
| 16 | Mitochondrial inheritance (HP:0001427) | 3.09328920 |
| 17 | Pendular nystagmus (HP:0012043) | 3.00826022 |
| 18 | Increased hepatocellular lipid droplets (HP:0006565) | 2.97230393 |
| 19 | Large for gestational age (HP:0001520) | 2.97122826 |
| 20 | Bile duct proliferation (HP:0001408) | 2.88520671 |
| 21 | Abnormal biliary tract physiology (HP:0012439) | 2.88520671 |
| 22 | Nephronophthisis (HP:0000090) | 2.75565393 |
| 23 | Abnormal spermatogenesis (HP:0008669) | 2.74605539 |
| 24 | Cerebral edema (HP:0002181) | 2.67317914 |
| 25 | Lipid accumulation in hepatocytes (HP:0006561) | 2.66424151 |
| 26 | Abnormality of secondary sexual hair (HP:0009888) | 2.62210268 |
| 27 | Abnormality of the axillary hair (HP:0100134) | 2.62210268 |
| 28 | Abnormal drinking behavior (HP:0030082) | 2.61591885 |
| 29 | Polydipsia (HP:0001959) | 2.61591885 |
| 30 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.61249832 |
| 31 | Pancytopenia (HP:0001876) | 2.59725614 |
| 32 | Methylmalonic acidemia (HP:0002912) | 2.56712339 |
| 33 | Increased serum lactate (HP:0002151) | 2.53674336 |
| 34 | Abolished electroretinogram (ERG) (HP:0000550) | 2.49310163 |
| 35 | Renal Fanconi syndrome (HP:0001994) | 2.47244071 |
| 36 | Inability to walk (HP:0002540) | 2.45162008 |
| 37 | Supernumerary spleens (HP:0009799) | 2.38549582 |
| 38 | Sclerocornea (HP:0000647) | 2.37211854 |
| 39 | Furrowed tongue (HP:0000221) | 2.34918090 |
| 40 | Cystic liver disease (HP:0006706) | 2.34177840 |
| 41 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.30718814 |
| 42 | Hepatocellular necrosis (HP:0001404) | 2.29861756 |
| 43 | Keratoconus (HP:0000563) | 2.29500064 |
| 44 | Increased corneal curvature (HP:0100692) | 2.29500064 |
| 45 | Abnormality of alanine metabolism (HP:0010916) | 2.27923959 |
| 46 | Hyperalaninemia (HP:0003348) | 2.27923959 |
| 47 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.27923959 |
| 48 | Lethargy (HP:0001254) | 2.22144694 |
| 49 | Abnormality of the renal medulla (HP:0100957) | 2.20795999 |
| 50 | Abnormality of the pons (HP:0007361) | 2.11050109 |
| 51 | Attenuation of retinal blood vessels (HP:0007843) | 2.10808133 |
| 52 | Testicular atrophy (HP:0000029) | 2.10046797 |
| 53 | Male pseudohermaphroditism (HP:0000037) | 2.08886770 |
| 54 | Polyuria (HP:0000103) | 2.08118240 |
| 55 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.06596832 |
| 56 | IgG deficiency (HP:0004315) | 2.06278612 |
| 57 | Abnormality of the renal cortex (HP:0011035) | 2.05665714 |
| 58 | Abnormality of the ileum (HP:0001549) | 2.05375405 |
| 59 | Methylmalonic aciduria (HP:0012120) | 2.03510172 |
| 60 | Enlarged epiphyses (HP:0010580) | 2.02944181 |
| 61 | Anencephaly (HP:0002323) | 2.02251523 |
| 62 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.01517677 |
| 63 | Meckel diverticulum (HP:0002245) | 2.01203419 |
| 64 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.99292545 |
| 65 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.98947451 |
| 66 | Optic disc pallor (HP:0000543) | 1.98313243 |
| 67 | Focal motor seizures (HP:0011153) | 1.97175427 |
| 68 | Congenital stationary night blindness (HP:0007642) | 1.97030594 |
| 69 | Chronic bronchitis (HP:0004469) | 1.96472963 |
| 70 | Posterior subcapsular cataract (HP:0007787) | 1.92087469 |
| 71 | Lactic acidosis (HP:0003128) | 1.91389490 |
| 72 | Autoimmune hemolytic anemia (HP:0001890) | 1.90939219 |
| 73 | Hepatic necrosis (HP:0002605) | 1.90630108 |
| 74 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.88564171 |
| 75 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.87462639 |
| 76 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.86854164 |
| 77 | Delayed CNS myelination (HP:0002188) | 1.86770619 |
| 78 | Hypoproteinemia (HP:0003075) | 1.86315810 |
| 79 | Abnormality of renal resorption (HP:0011038) | 1.86155106 |
| 80 | Congenital hepatic fibrosis (HP:0002612) | 1.83865074 |
| 81 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.83110146 |
| 82 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.81446675 |
| 83 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.81446675 |
| 84 | Postaxial foot polydactyly (HP:0001830) | 1.81157581 |
| 85 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.79853101 |
| 86 | Palpitations (HP:0001962) | 1.77908566 |
| 87 | Hyperglycinuria (HP:0003108) | 1.76449671 |
| 88 | Type II lissencephaly (HP:0007260) | 1.75326708 |
| 89 | Aplastic anemia (HP:0001915) | 1.72528400 |
| 90 | Medial flaring of the eyebrow (HP:0010747) | 1.72435100 |
| 91 | Abnormality of B cell number (HP:0010975) | 1.71964628 |
| 92 | Abnormal ciliary motility (HP:0012262) | 1.71213522 |
| 93 | Abnormality of the costochondral junction (HP:0000919) | 1.69978924 |
| 94 | Type 2 muscle fiber atrophy (HP:0003554) | 1.68452563 |
| 95 | Leukodystrophy (HP:0002415) | 1.68241288 |
| 96 | Bilateral microphthalmos (HP:0007633) | 1.65740958 |
| 97 | Palpebral edema (HP:0100540) | 1.64859902 |
| 98 | Hypoplasia of the pons (HP:0012110) | 1.64398694 |
| 99 | Abnormal urine output (HP:0012590) | 1.63274515 |
| 100 | 3-Methylglutaconic aciduria (HP:0003535) | 1.62798992 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NUAK1 | 4.59891530 |
| 2 | FRK | 3.95336305 |
| 3 | EIF2AK3 | 3.03931726 |
| 4 | SIK2 | 3.01690538 |
| 5 | TRIM28 | 2.95471189 |
| 6 | ZAK | 2.87054763 |
| 7 | PINK1 | 2.80401771 |
| 8 | TSSK6 | 2.62516007 |
| 9 | EIF2AK1 | 2.36953299 |
| 10 | PDK2 | 2.33550623 |
| 11 | PASK | 2.30458971 |
| 12 | MKNK2 | 2.20300798 |
| 13 | WNK4 | 2.00957359 |
| 14 | SRPK1 | 1.82302823 |
| 15 | PNCK | 1.78061938 |
| 16 | MKNK1 | 1.73812478 |
| 17 | TLK1 | 1.70059233 |
| 18 | VRK2 | 1.67379720 |
| 19 | MST4 | 1.66243198 |
| 20 | ADRBK2 | 1.64632224 |
| 21 | MAP4K2 | 1.60885734 |
| 22 | STK39 | 1.56760747 |
| 23 | STK16 | 1.54908931 |
| 24 | BUB1 | 1.54495327 |
| 25 | OXSR1 | 1.54383599 |
| 26 | DMPK | 1.51726192 |
| 27 | NTRK3 | 1.40023760 |
| 28 | INSRR | 1.39930753 |
| 29 | GRK1 | 1.38397521 |
| 30 | TXK | 1.37896524 |
| 31 | BCR | 1.37532032 |
| 32 | MAPKAPK3 | 1.27084895 |
| 33 | PLK3 | 1.26419085 |
| 34 | WNK3 | 1.16677341 |
| 35 | VRK1 | 1.09304400 |
| 36 | CDC7 | 1.03007253 |
| 37 | PIK3CG | 1.02640442 |
| 38 | TNIK | 0.98236392 |
| 39 | BCKDK | 0.97408154 |
| 40 | MINK1 | 0.92590555 |
| 41 | PLK1 | 0.91565853 |
| 42 | NEK1 | 0.89173881 |
| 43 | PLK2 | 0.87679987 |
| 44 | EIF2AK2 | 0.86006593 |
| 45 | TEC | 0.85849299 |
| 46 | TAOK3 | 0.81724970 |
| 47 | RPS6KA5 | 0.78078694 |
| 48 | MAPK13 | 0.77745100 |
| 49 | CASK | 0.75862184 |
| 50 | TYRO3 | 0.73907862 |
| 51 | ACVR1B | 0.70798402 |
| 52 | CHEK2 | 0.70742794 |
| 53 | PLK4 | 0.70650526 |
| 54 | TIE1 | 0.69462667 |
| 55 | BMPR1B | 0.67824118 |
| 56 | PHKG1 | 0.66615850 |
| 57 | PHKG2 | 0.66615850 |
| 58 | DYRK2 | 0.66007466 |
| 59 | TTK | 0.65820991 |
| 60 | MAPKAPK5 | 0.65382912 |
| 61 | CSNK1G3 | 0.65374254 |
| 62 | ATR | 0.63268840 |
| 63 | MAP3K9 | 0.62651629 |
| 64 | CSNK1G2 | 0.60685989 |
| 65 | ITK | 0.58618891 |
| 66 | RAF1 | 0.57438098 |
| 67 | DAPK2 | 0.57405728 |
| 68 | ILK | 0.55923860 |
| 69 | PRKCG | 0.54124278 |
| 70 | ADRBK1 | 0.52527132 |
| 71 | WEE1 | 0.52184973 |
| 72 | PRKCQ | 0.51718275 |
| 73 | ALK | 0.50596084 |
| 74 | CSNK1G1 | 0.49847922 |
| 75 | NME1 | 0.49823529 |
| 76 | MAP2K6 | 0.48658561 |
| 77 | TGFBR1 | 0.46959039 |
| 78 | SIK3 | 0.46006513 |
| 79 | IKBKB | 0.45082534 |
| 80 | RPS6KA4 | 0.40963965 |
| 81 | CSNK1A1L | 0.40214586 |
| 82 | CSNK1A1 | 0.39521532 |
| 83 | CCNB1 | 0.37691625 |
| 84 | DAPK1 | 0.36274820 |
| 85 | MAPK11 | 0.35442322 |
| 86 | OBSCN | 0.35397976 |
| 87 | PRKACA | 0.34818598 |
| 88 | CSNK2A1 | 0.34684839 |
| 89 | STK38L | 0.32278271 |
| 90 | CAMK2A | 0.31154365 |
| 91 | ATM | 0.29575406 |
| 92 | KIT | 0.28412209 |
| 93 | PRKCE | 0.28038700 |
| 94 | NEK6 | 0.27786167 |
| 95 | PRKCA | 0.26636469 |
| 96 | STK3 | 0.25985504 |
| 97 | LATS1 | 0.25868866 |
| 98 | NME2 | 0.25416758 |
| 99 | PRKCI | 0.25295144 |
| 100 | MAP3K4 | 0.25161047 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Selenocompound metabolism_Homo sapiens_hsa00450 | 4.10241883 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.99818534 |
| 3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.21459586 |
| 4 | Asthma_Homo sapiens_hsa05310 | 2.63647326 |
| 5 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.33750628 |
| 6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.29947627 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.29807292 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.10379192 |
| 9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.03139783 |
| 10 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.01430106 |
| 11 | Parkinsons disease_Homo sapiens_hsa05012 | 1.94802940 |
| 12 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.84779757 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 1.79478312 |
| 14 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.76999110 |
| 15 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.73729847 |
| 16 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.73531332 |
| 17 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.70645714 |
| 18 | Allograft rejection_Homo sapiens_hsa05330 | 1.63095997 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.62780958 |
| 20 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.62223465 |
| 21 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.60280619 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.55255908 |
| 23 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.53519480 |
| 24 | RNA transport_Homo sapiens_hsa03013 | 1.48304706 |
| 25 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.47605403 |
| 26 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.41256957 |
| 27 | Huntingtons disease_Homo sapiens_hsa05016 | 1.38178571 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.33320095 |
| 29 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.32091348 |
| 30 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.31956466 |
| 31 | Alzheimers disease_Homo sapiens_hsa05010 | 1.26651322 |
| 32 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.23549321 |
| 33 | Nicotine addiction_Homo sapiens_hsa05033 | 1.22577410 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.20181171 |
| 35 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.20023110 |
| 36 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.18890566 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 1.17977729 |
| 38 | Phototransduction_Homo sapiens_hsa04744 | 1.13439357 |
| 39 | Taste transduction_Homo sapiens_hsa04742 | 1.10364180 |
| 40 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.08601093 |
| 41 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.06663877 |
| 42 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.06389621 |
| 43 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.04409851 |
| 44 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.98386818 |
| 45 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.98156072 |
| 46 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.97271803 |
| 47 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.96928408 |
| 48 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.96889488 |
| 49 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.90967187 |
| 50 | DNA replication_Homo sapiens_hsa03030 | 0.89516507 |
| 51 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.88249365 |
| 52 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.84982750 |
| 53 | Olfactory transduction_Homo sapiens_hsa04740 | 0.83947897 |
| 54 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.81641638 |
| 55 | Ribosome_Homo sapiens_hsa03010 | 0.81304487 |
| 56 | Spliceosome_Homo sapiens_hsa03040 | 0.80350631 |
| 57 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.79103643 |
| 58 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.78355645 |
| 59 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.77394387 |
| 60 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.77165184 |
| 61 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.76701544 |
| 62 | Peroxisome_Homo sapiens_hsa04146 | 0.76246697 |
| 63 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.74522632 |
| 64 | Mismatch repair_Homo sapiens_hsa03430 | 0.73535231 |
| 65 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.72386064 |
| 66 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.71738959 |
| 67 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.71717580 |
| 68 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.69201568 |
| 69 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.68510858 |
| 70 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.68044378 |
| 71 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.66463121 |
| 72 | Metabolic pathways_Homo sapiens_hsa01100 | 0.65121286 |
| 73 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.64770269 |
| 74 | Morphine addiction_Homo sapiens_hsa05032 | 0.63162108 |
| 75 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.62454850 |
| 76 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.62117160 |
| 77 | Circadian entrainment_Homo sapiens_hsa04713 | 0.60330838 |
| 78 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.59900470 |
| 79 | ABC transporters_Homo sapiens_hsa02010 | 0.58280024 |
| 80 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.57969884 |
| 81 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.57328892 |
| 82 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.57168034 |
| 83 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.53110842 |
| 84 | Retinol metabolism_Homo sapiens_hsa00830 | 0.52277559 |
| 85 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.47225718 |
| 86 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.46591361 |
| 87 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.43245425 |
| 88 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.42728812 |
| 89 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.42160912 |
| 90 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40807715 |
| 91 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.40804908 |
| 92 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.36949412 |
| 93 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.36719022 |
| 94 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.36457946 |
| 95 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.35758201 |
| 96 | Viral myocarditis_Homo sapiens_hsa05416 | 0.34930424 |
| 97 | GABAergic synapse_Homo sapiens_hsa04727 | 0.34852970 |
| 98 | Salivary secretion_Homo sapiens_hsa04970 | 0.32502956 |
| 99 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.32097553 |
| 100 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.31617052 |

