TCTEX1D1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium movement (GO:0003341)9.50165475
2sperm-egg recognition (GO:0035036)9.37929650
3acrosome assembly (GO:0001675)8.96189182
4acrosome reaction (GO:0007340)8.83287126
5cilium or flagellum-dependent cell motility (GO:0001539)8.74081035
6binding of sperm to zona pellucida (GO:0007339)8.66975343
7reproduction (GO:0000003)8.61467050
8cell-cell recognition (GO:0009988)8.39205370
9motile cilium assembly (GO:0044458)8.27119711
10epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.95939026
11plasma membrane fusion (GO:0045026)7.82032177
12piRNA metabolic process (GO:0034587)7.80169872
13spermatid development (GO:0007286)7.69821477
14male meiosis (GO:0007140)7.16941353
15single fertilization (GO:0007338)6.91747613
16regulation of cilium movement (GO:0003352)6.25912073
17synaptonemal complex organization (GO:0070193)6.20648672
18synaptonemal complex assembly (GO:0007130)6.14165704
19microtubule depolymerization (GO:0007019)6.14019070
20fertilization (GO:0009566)5.94384519
21negative regulation of inclusion body assembly (GO:0090084)5.82893480
22spermatogenesis (GO:0007283)5.63975940
23male gamete generation (GO:0048232)5.62146694
24sperm capacitation (GO:0048240)5.48104530
25spermatid nucleus differentiation (GO:0007289)5.47916380
26gamete generation (GO:0007276)5.38072314
27DNA methylation involved in gamete generation (GO:0043046)5.20539622
28microtubule bundle formation (GO:0001578)5.05179067
29male meiosis I (GO:0007141)4.96450945
30microtubule severing (GO:0051013)4.95312659
31meiotic cell cycle (GO:0051321)4.86206248
32ventricular system development (GO:0021591)4.75114895
33single strand break repair (GO:0000012)4.73058373
34primary alcohol catabolic process (GO:0034310)4.68947420
35chromosome condensation (GO:0030261)4.63234964
36chromosome organization involved in meiosis (GO:0070192)4.60916806
37regulation of inclusion body assembly (GO:0090083)4.59675589
38meiotic nuclear division (GO:0007126)4.49014180
39germ cell development (GO:0007281)4.39427602
40cellular process involved in reproduction in multicellular organism (GO:0022412)4.38757403
41protein localization to cilium (GO:0061512)4.36554004
42ethanol metabolic process (GO:0006067)4.33314787
43DNA packaging (GO:0006323)4.28845296
44glycerol ether metabolic process (GO:0006662)4.22201464
45axoneme assembly (GO:0035082)4.20274219
46multicellular organismal reproductive process (GO:0048609)4.19074266
47organic cation transport (GO:0015695)4.18736250
48definitive hemopoiesis (GO:0060216)4.18193355
49meiosis I (GO:0007127)4.09668065
50cell projection assembly (GO:0030031)4.03544862
51calcium ion-dependent exocytosis (GO:0017156)4.02657387
52vitamin transmembrane transport (GO:0035461)4.01753366
53monoubiquitinated protein deubiquitination (GO:0035520)4.00736001
54centriole assembly (GO:0098534)3.91110499
55cell recognition (GO:0008037)3.90854781
56ether metabolic process (GO:0018904)3.87820472
57lateral ventricle development (GO:0021670)3.87288450
58response to xenobiotic stimulus (GO:0009410)3.86628425
59microtubule polymerization or depolymerization (GO:0031109)3.85403978
60mitotic sister chromatid cohesion (GO:0007064)3.78475060
61epithelial cell differentiation involved in kidney development (GO:0035850)3.77874688
62intra-S DNA damage checkpoint (GO:0031573)3.67952497
63nucleoside diphosphate phosphorylation (GO:0006165)3.66487180
64centriole replication (GO:0007099)3.65139590
65axon ensheathment in central nervous system (GO:0032291)3.63006073
66central nervous system myelination (GO:0022010)3.63006073
67potassium ion export (GO:0071435)3.60670107
68protein polyglutamylation (GO:0018095)3.60028646
69tolerance induction (GO:0002507)3.55079905
70meiotic cell cycle process (GO:1903046)3.51236287
71pyrimidine-containing compound transmembrane transport (GO:0072531)3.50139951
72regulation of microtubule-based movement (GO:0060632)3.48804777
73histone exchange (GO:0043486)3.48005414
74protein localization to chromosome, centromeric region (GO:0071459)3.46448914
75cilium organization (GO:0044782)3.43822126
76regulation of germinal center formation (GO:0002634)3.43499074
77female gonad development (GO:0008585)3.41935692
78ethanol oxidation (GO:0006069)3.37339108
79diterpenoid biosynthetic process (GO:0016102)3.34984494
80sleep (GO:0030431)3.33497491
81GTP biosynthetic process (GO:0006183)3.32120811
82negative regulation of immunoglobulin mediated immune response (GO:0002890)3.30899292
83negative regulation of B cell mediated immunity (GO:0002713)3.30899292
84meiotic chromosome segregation (GO:0045132)3.26859804
85cilium assembly (GO:0042384)3.26835034
86regulation of meiosis I (GO:0060631)3.24545337
87regulation of spindle checkpoint (GO:0090231)3.23491539
88regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.18516363
89protein K11-linked deubiquitination (GO:0035871)3.13716999
90left/right axis specification (GO:0070986)3.12538962
91multicellular organismal development (GO:0007275)3.12330069
92one-carbon compound transport (GO:0019755)3.10842769
93negative regulation of T cell differentiation in thymus (GO:0033085)3.09543022
94retinal rod cell development (GO:0046548)3.08873900
95protein refolding (GO:0042026)3.07948688
96intraciliary transport (GO:0042073)3.07794766
97mitotic sister chromatid segregation (GO:0000070)3.06117595
98sister chromatid cohesion (GO:0007062)3.04462257
99determination of left/right symmetry (GO:0007368)3.04258105
100lateral sprouting from an epithelium (GO:0060601)3.02996713
101cellular component assembly involved in morphogenesis (GO:0010927)3.00445854
102smoothened signaling pathway (GO:0007224)2.99955561
103sexual reproduction (GO:0019953)2.99518683
104phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.99261983
105microtubule-based movement (GO:0007018)2.99047056
106negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)2.96629606
107negative regulation of oligodendrocyte differentiation (GO:0048715)2.96145733
108establishment of planar polarity (GO:0001736)2.96033283
109establishment of tissue polarity (GO:0007164)2.96033283
110left/right pattern formation (GO:0060972)2.95906463
111genitalia morphogenesis (GO:0035112)2.94422958
112negative regulation of humoral immune response (GO:0002921)2.93233004
113embryonic heart tube development (GO:0035050)2.92566390
114negative regulation of retinoic acid receptor signaling pathway (GO:0048387)2.90241049
115UTP biosynthetic process (GO:0006228)2.88494138
116synapsis (GO:0007129)2.88235712
117regulation of female gonad development (GO:2000194)2.86605372
118maternal behavior (GO:0042711)2.84882939
119determination of bilateral symmetry (GO:0009855)2.84586845
120positive regulation of tolerance induction (GO:0002645)2.83671659
121regulation of acrosome reaction (GO:0060046)2.82785514
122cilium morphogenesis (GO:0060271)2.81762292
123nucleus organization (GO:0006997)2.81016033
124gene silencing by RNA (GO:0031047)2.80372038
125specification of symmetry (GO:0009799)2.77631806
126protein K6-linked ubiquitination (GO:0085020)2.77172557
127mitotic chromosome condensation (GO:0007076)2.72991358
128female gamete generation (GO:0007292)2.72763266
129eye photoreceptor cell differentiation (GO:0001754)2.71280357
130photoreceptor cell differentiation (GO:0046530)2.71280357
131regulation of exit from mitosis (GO:0007096)2.70251534
132endothelium development (GO:0003158)2.69180156
133interkinetic nuclear migration (GO:0022027)2.68112359
134lung epithelium development (GO:0060428)2.67311315
135regulation of interleukin-13 production (GO:0032656)2.67247606
136oocyte maturation (GO:0001556)2.67012816
137regulation of meiosis (GO:0040020)2.66222038
138regulation of interleukin-5 production (GO:0032674)2.65456238
139seminiferous tubule development (GO:0072520)2.63252745
140hematopoietic stem cell proliferation (GO:0071425)2.59367499
141polyamine biosynthetic process (GO:0006596)2.59186494
142cytoplasmic microtubule organization (GO:0031122)2.55863489
143retinoic acid metabolic process (GO:0042573)2.53240168
144carnitine metabolic process (GO:0009437)2.52575124
145glutathione derivative metabolic process (GO:1901685)2.52097780
146glutathione derivative biosynthetic process (GO:1901687)2.52097780
147parental behavior (GO:0060746)2.51744630
148hypotonic response (GO:0006971)2.51155284
149neuronal stem cell maintenance (GO:0097150)2.50736139
150thrombin receptor signaling pathway (GO:0070493)2.49849735
151heart looping (GO:0001947)2.49272901
152exogenous drug catabolic process (GO:0042738)2.47517878
153organelle assembly (GO:0070925)2.46163205
154establishment of apical/basal cell polarity (GO:0035089)2.45880331
155positive regulation of steroid hormone secretion (GO:2000833)2.45226428
156positive regulation of smoothened signaling pathway (GO:0045880)2.44863564
157terpenoid biosynthetic process (GO:0016114)2.32405980
158embryonic heart tube morphogenesis (GO:0003143)2.29430411
159photoreceptor cell maintenance (GO:0045494)2.27534508
160aldehyde catabolic process (GO:0046185)2.26655327
161neurotransmitter catabolic process (GO:0042135)2.25973128
162reactive oxygen species biosynthetic process (GO:1903409)2.25804840
163neural tube formation (GO:0001841)2.25346502
164microtubule-based process (GO:0007017)2.22357415
165glomerular epithelial cell development (GO:0072310)2.21867687
166cell wall macromolecule catabolic process (GO:0016998)11.3588097
167cell wall macromolecule metabolic process (GO:0044036)11.3588097
168axonemal dynein complex assembly (GO:0070286)10.4318482
169fusion of sperm to egg plasma membrane (GO:0007342)10.4087125
170multicellular organism reproduction (GO:0032504)10.2202372
171sperm motility (GO:0030317)10.0862465
172epithelial cilium movement (GO:0003351)10.0428608

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse6.53485342
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.99274556
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.44687575
4DROSHA_22980978_ChIP-Seq_HELA_Human3.05262163
5EZH2_22144423_ChIP-Seq_EOC_Human2.98182445
6MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.78044048
7FLI1_27457419_Chip-Seq_LIVER_Mouse2.75500307
8KAP1_22055183_ChIP-Seq_ESCs_Mouse2.72140612
9PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.67065975
10CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.62201203
11SCL_19346495_ChIP-Seq_HPC-7_Human2.56787113
12PCGF2_27294783_Chip-Seq_ESCs_Mouse2.49904918
13GATA1_26923725_Chip-Seq_HPCs_Mouse2.42294225
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.42217188
15HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.26992201
16FOXM1_23109430_ChIP-Seq_U2OS_Human2.26347611
17PIAS1_25552417_ChIP-Seq_VCAP_Human2.21326024
18GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.20937720
19IRF8_22096565_ChIP-ChIP_GC-B_Human2.13704615
20NR3C1_21868756_ChIP-Seq_MCF10A_Human2.08708446
21STAT6_21828071_ChIP-Seq_BEAS2B_Human2.04423801
22VDR_22108803_ChIP-Seq_LS180_Human2.03004798
23ESR1_20079471_ChIP-ChIP_T-47D_Human2.00184392
24CBX2_27304074_Chip-Seq_ESCs_Mouse1.99629690
25* FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.97272161
26KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.89000605
27SUZ12_27294783_Chip-Seq_NPCs_Mouse1.87310908
28STAT1_17558387_ChIP-Seq_HELA_Human1.87029953
29ZFP57_27257070_Chip-Seq_ESCs_Mouse1.86323871
30TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.84642683
31NFE2_27457419_Chip-Seq_LIVER_Mouse1.83896368
32MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.82876172
33TAL1_26923725_Chip-Seq_HPCs_Mouse1.81322348
34* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.80528245
35KDM2B_26808549_Chip-Seq_REH_Human1.74066790
36RNF2_27304074_Chip-Seq_NSC_Mouse1.73409995
37EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.70917361
38RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.70705005
39* NANOG_18555785_Chip-Seq_ESCs_Mouse1.69999474
40TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.65397473
41PCGF2_27294783_Chip-Seq_NPCs_Mouse1.64832766
42CTBP2_25329375_ChIP-Seq_LNCAP_Human1.64817038
43* GATA1_19941826_ChIP-Seq_K562_Human1.64296773
44EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.63890322
45FOXM1_26456572_ChIP-Seq_MCF-7_Human1.62949927
46EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.61589385
47ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.56482164
48MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.56136005
49TOP2B_26459242_ChIP-Seq_MCF-7_Human1.55955441
50EZH2_27294783_Chip-Seq_NPCs_Mouse1.55203276
51* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.52917498
52AHR_22903824_ChIP-Seq_MCF-7_Human1.52627159
53CTBP1_25329375_ChIP-Seq_LNCAP_Human1.52491829
54ELK4_26923725_Chip-Seq_MESODERM_Mouse1.51994854
55OCT4_18555785_Chip-Seq_ESCs_Mouse1.50234975
56P53_22387025_ChIP-Seq_ESCs_Mouse1.49958747
57EWS_26573619_Chip-Seq_HEK293_Human1.49767302
58CMYC_18555785_Chip-Seq_ESCs_Mouse1.49409918
59CRX_20693478_ChIP-Seq_RETINA_Mouse1.48707322
60SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.48550563
61STAT3_18555785_Chip-Seq_ESCs_Mouse1.48545307
62IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.47010035
63GATA3_21867929_ChIP-Seq_TH1_Mouse1.46820324
64CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.46208898
65KLF4_18555785_Chip-Seq_ESCs_Mouse1.45573222
66ELF1_17652178_ChIP-ChIP_JURKAT_Human1.44154278
67TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42666819
68POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.42666819
69ARNT_22903824_ChIP-Seq_MCF-7_Human1.42598372
70EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.41280166
71STAT1_20625510_ChIP-Seq_HELA_Human1.41162898
72SMAD4_21799915_ChIP-Seq_A2780_Human1.40303991
73SOX2_18555785_Chip-Seq_ESCs_Mouse1.40001666
74SUZ12_18555785_Chip-Seq_ESCs_Mouse1.39799142
75P300_18555785_Chip-Seq_ESCs_Mouse1.39171086
76TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.39016628
77FUS_26573619_Chip-Seq_HEK293_Human1.36786370
78ER_23166858_ChIP-Seq_MCF-7_Human1.35641420
79SMRT_27268052_Chip-Seq_Bcells_Human1.33505437
80PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.33462961
81ESRRB_18555785_Chip-Seq_ESCs_Mouse1.32209787
82RUNX_20019798_ChIP-Seq_JUKART_Human1.30425729
83CTCF_18555785_Chip-Seq_ESCs_Mouse1.29865106
84GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.29851650
85SOX2_22085726_ChIP-Seq_NPCs_Mouse1.29829067
86FLI1_21867929_ChIP-Seq_TH2_Mouse1.29044207
87CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.28527462
88NMYC_18555785_Chip-Seq_ESCs_Mouse1.28383007
89GBX2_23144817_ChIP-Seq_PC3_Human1.27461478
90FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.27458746
91FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.25816956
92LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25695036
93OCT4_21477851_ChIP-Seq_ESCs_Mouse1.25539710
94* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.24699552
95TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24607012
96RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24368592
97TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.24020925
98E2F1_18555785_Chip-Seq_ESCs_Mouse1.23683068
99* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.23382324
100BCAT_22108803_ChIP-Seq_LS180_Human1.23249993
101* GATA3_21867929_ChIP-Seq_CD8_Mouse1.23022119
102* FOXA1_21572438_ChIP-Seq_LNCaP_Human1.22553230
103WDR5_24793694_ChIP-Seq_LNCAP_Human1.21835546
104FOXA1_25552417_ChIP-Seq_VCAP_Human1.21751559
105RUNX1_27457419_Chip-Seq_LIVER_Mouse1.21366392
106GF1_26923725_Chip-Seq_HPCs_Mouse1.20960038
107ZNF217_24962896_ChIP-Seq_MCF-7_Human1.20868330
108PU1_27457419_Chip-Seq_LIVER_Mouse1.20594824
109ZFX_18555785_Chip-Seq_ESCs_Mouse1.20346894
110AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.20080317
111RUNX1_26923725_Chip-Seq_HPCs_Mouse1.19768102
112FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.18786543
113* STAT3_23295773_ChIP-Seq_U87_Human1.18475332
114STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.16494037
115TAF15_26573619_Chip-Seq_HEK293_Human1.16160604
116* TBL1_22424771_ChIP-Seq_293T_Human1.15553537
117NRF2_20460467_ChIP-Seq_MEFs_Mouse1.13442014
118NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.13442014
119AR_21572438_ChIP-Seq_LNCaP_Human1.13096247
120CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.11862783
121* VDR_24787735_ChIP-Seq_THP-1_Human1.10959726
122SMAD3_21741376_ChIP-Seq_EPCs_Human1.10214719
123SMAD1_18555785_Chip-Seq_ESCs_Mouse1.10183917
124* HNFA_21074721_ChIP-Seq_CACO-2_Human1.10068333
125* NFYB_21822215_ChIP-Seq_K562_Human1.10043903
126* GATA2_19941826_ChIP-Seq_K562_Human1.09760211
127* FOXA1_25329375_ChIP-Seq_VCAP_Human1.09619682
128* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.09619682
129SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.08071773
130TP63_23658742_ChIP-Seq_EP156T_Human1.07881213
131CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07533939
132CEBPB_22108803_ChIP-Seq_LS180_Human1.07184564
133GF1B_26923725_Chip-Seq_HPCs_Mouse1.06467368
134* ETV1_20927104_ChIP-Seq_GIST48_Human1.06387898
135* CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.06110512
136SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.05203445
137BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.05064792
138PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.04508329
139SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.03459528
140AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.03435166
141CTNNB1_20460455_ChIP-Seq_HCT116_Human1.03177213
142TCF4_22108803_ChIP-Seq_LS180_Human1.02958440
143* SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02867107
144IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.02832312
145CBP_20019798_ChIP-Seq_JUKART_Human1.02832312
146ESET_19884257_ChIP-Seq_ESCs_Mouse1.01409966
147P300_19829295_ChIP-Seq_ESCs_Human1.00997669
148CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.00199479
149SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.99545065
150PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.99101395
151* NFYA_21822215_ChIP-Seq_K562_Human0.99094564
152LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98964406
153AR_20517297_ChIP-Seq_VCAP_Human0.98641325
154CDX2_19796622_ChIP-Seq_MESCs_Mouse0.98139063
155* CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.98027918
156LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.98004152
157ERG_20517297_ChIP-Seq_VCAP_Human0.97547903
158SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.97430566
159YY1_22570637_ChIP-Seq_MALME-3M_Human0.97151202
160VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.96798384
161LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.96538989
162TCF4_23295773_ChIP-Seq_U87_Human0.95948240
163ZNF274_21170338_ChIP-Seq_K562_Hela0.95812526
164REST_21632747_ChIP-Seq_MESCs_Mouse0.95684781
165* PHF8_20622853_ChIP-Seq_HELA_Human0.95345495
166GATA1_22025678_ChIP-Seq_K562_Human0.94308880
167EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.91302406
168VDR_24763502_ChIP-Seq_THP-1_Human0.90560836
169SOX2_27498859_Chip-Seq_STOMACH_Mouse0.90426786
170RXR_22108803_ChIP-Seq_LS180_Human0.89938290
171PRDM14_20953172_ChIP-Seq_ESCs_Human0.89327598
172GATA3_21878914_ChIP-Seq_MCF-7_Human0.89247142
173TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.88946177
174CDX2_22108803_ChIP-Seq_LS180_Human0.88866353
175* PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.87519727

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001929_abnormal_gametogenesis5.19438718
2MP0003698_abnormal_male_reproductive5.03321793
3MP0008877_abnormal_DNA_methylation4.81079117
4MP0008875_abnormal_xenobiotic_pharmacok3.94929941
5MP0002210_abnormal_sex_determination3.39733473
6MP0000465_gastrointestinal_hemorrhage3.19444983
7MP0002102_abnormal_ear_morphology3.12295671
8MP0002161_abnormal_fertility/fecundity3.10500476
9MP0003646_muscle_fatigue3.03229574
10MP0002653_abnormal_ependyma_morphology2.94234832
11MP0005377_hearing/vestibular/ear_phenot2.82471449
12MP0003878_abnormal_ear_physiology2.82471449
13MP0000653_abnormal_sex_gland2.81712892
14MP0001145_abnormal_male_reproductive2.80828886
15MP0005084_abnormal_gallbladder_morpholo2.75730279
16MP0004133_heterotaxia2.66872892
17MP0003303_peritoneal_inflammation2.45660858
18MP0001485_abnormal_pinna_reflex2.44972263
19MP0010094_abnormal_chromosome_stability2.44887210
20MP0002277_abnormal_respiratory_mucosa2.43910501
21MP0003718_maternal_effect2.33428601
22MP0008057_abnormal_DNA_replication2.20429752
23MP0005451_abnormal_body_composition2.13856382
24MP0005464_abnormal_platelet_physiology2.08808209
25MP0005410_abnormal_fertilization12.0483349
26MP0009379_abnormal_foot_pigmentation1.96838364
27MP0004885_abnormal_endolymph1.89057644
28MP0004043_abnormal_pH_regulation1.87751484
29MP0008058_abnormal_DNA_repair1.76642169
30MP0003111_abnormal_nucleus_morphology1.76292867
31MP0003136_yellow_coat_color1.69162874
32MP0003693_abnormal_embryo_hatching1.66192961
33MP0003283_abnormal_digestive_organ1.61825946
34MP0002160_abnormal_reproductive_system1.59879790
35MP0004808_abnormal_hematopoietic_stem1.57206240
36MP0003077_abnormal_cell_cycle1.56609627
37MP0000462_abnormal_digestive_system1.51772546
38MP0003943_abnormal_hepatobiliary_system1.51759603
39MP0003656_abnormal_erythrocyte_physiolo1.51711226
40MP0001119_abnormal_female_reproductive1.46050304
41MP0010368_abnormal_lymphatic_system1.45182208
42MP0003699_abnormal_female_reproductive1.41099085
43MP0009278_abnormal_bone_marrow1.34391586
44MP0005165_increased_susceptibility_to1.26503466
45MP0001663_abnormal_digestive_system1.26065620
46MP0001664_abnormal_digestion1.24592950
47MP0003724_increased_susceptibility_to1.23716531
48MP0002735_abnormal_chemical_nociception1.17999789
49MP0003075_altered_response_to1.16747528
50MP0005670_abnormal_white_adipose1.16691075
51MP0003806_abnormal_nucleotide_metabolis1.13970359
52MP0000343_altered_response_to1.13192441
53MP0002638_abnormal_pupillary_reflex1.13062922
54MP0005389_reproductive_system_phenotype1.11385513
55MP0005174_abnormal_tail_pigmentation1.09763902
56MP0001529_abnormal_vocalization1.06837851
57MP0002876_abnormal_thyroid_physiology1.06591221
58MP0002822_catalepsy1.06389113
59MP0001293_anophthalmia1.05563061
60MP0005647_abnormal_sex_gland1.05417790
61MP0001765_abnormal_ion_homeostasis1.03733085
62MP0002282_abnormal_trachea_morphology0.97027647
63MP0004019_abnormal_vitamin_homeostasis0.96972806
64MP0005395_other_phenotype0.93560429
65MP0002009_preneoplasia0.92735405
66MP0008004_abnormal_stomach_pH0.91896997
67MP0002139_abnormal_hepatobiliary_system0.91737897
68MP0003950_abnormal_plasma_membrane0.90130352
69MP0006292_abnormal_olfactory_placode0.90062123
70MP0005220_abnormal_exocrine_pancreas0.89163648
71MP0002249_abnormal_larynx_morphology0.88607899
72MP0001905_abnormal_dopamine_level0.88017750
73MP0005646_abnormal_pituitary_gland0.87595595
74MP0001879_abnormal_lymphatic_vessel0.86408988
75MP0010155_abnormal_intestine_physiology0.86398781
76MP0002148_abnormal_hypersensitivity_rea0.85059098
77MP0002234_abnormal_pharynx_morphology0.83638755
78MP0000579_abnormal_nail_morphology0.83487497
79MP0005636_abnormal_mineral_homeostasis0.82399612
80MP0008789_abnormal_olfactory_epithelium0.81479071
81MP0001270_distended_abdomen0.81255130
82MP0009046_muscle_twitch0.80891769
83MP0001835_abnormal_antigen_presentation0.80231099
84MP0002736_abnormal_nociception_after0.80164944
85MP0005397_hematopoietic_system_phenotyp0.79150829
86MP0001545_abnormal_hematopoietic_system0.79150829
87MP0000383_abnormal_hair_follicle0.77531596
88MP0003937_abnormal_limbs/digits/tail_de0.76376010
89MP0006072_abnormal_retinal_apoptosis0.76347292
90MP0001851_eye_inflammation0.76079921
91MP0005083_abnormal_biliary_tract0.75833299
92MP0000681_abnormal_thyroid_gland0.74525934
93MP0005381_digestive/alimentary_phenotyp0.73952939
94MP0001188_hyperpigmentation0.72949673
95MP0005623_abnormal_meninges_morphology0.72647389
96MP0004957_abnormal_blastocyst_morpholog0.72373880
97MP0006082_CNS_inflammation0.70710216
98MP0008007_abnormal_cellular_replicative0.69047864
99MP0001986_abnormal_taste_sensitivity0.68747315
100MP0002168_other_aberrant_phenotype0.68521487
101MP0001984_abnormal_olfaction0.67481299
102MP0003633_abnormal_nervous_system0.66784689
103MP0000427_abnormal_hair_cycle0.66451733
104MP0003879_abnormal_hair_cell0.65980925
105MP0005171_absent_coat_pigmentation0.65317927
106MP0002396_abnormal_hematopoietic_system0.65213750
107MP0005164_abnormal_response_to0.64264973
108MP0001324_abnormal_eye_pigmentation0.64189963
109MP0001849_ear_inflammation0.63580252
110MP0004233_abnormal_muscle_weight0.63503704
111MP0001486_abnormal_startle_reflex0.63116988
112MP0004142_abnormal_muscle_tone0.62426125
113MP0008932_abnormal_embryonic_tissue0.62066728
114MP0005365_abnormal_bile_salt0.61991626
115MP0003787_abnormal_imprinting0.61729759
116MP0000249_abnormal_blood_vessel0.59862498
117MP0003632_abnormal_nervous_system0.59721480
118MP0001970_abnormal_pain_threshold0.59143620
119MP0000613_abnormal_salivary_gland0.58740201
120MP0003329_amyloid_beta_deposits0.58526241
121MP0003183_abnormal_peptide_metabolism0.58215195
122MP0003631_nervous_system_phenotype0.57384834
123MP0000013_abnormal_adipose_tissue0.55899289
124MP0002006_tumorigenesis0.54942919
125MP0009765_abnormal_xenobiotic_induced0.54505872
126MP0002419_abnormal_innate_immunity0.54028475
127MP0010386_abnormal_urinary_bladder0.53616399
128MP0002928_abnormal_bile_duct0.52563236
129MP0009643_abnormal_urine_homeostasis0.52171961
130MP0000566_synostosis0.51817955
131MP0002019_abnormal_tumor_incidence0.51562620
132MP0000230_abnormal_systemic_arterial0.51327726
133MP0001919_abnormal_reproductive_system0.51099399
134MP0005085_abnormal_gallbladder_physiolo0.50135780
135MP0004381_abnormal_hair_follicle0.49730654
136MP0004145_abnormal_muscle_electrophysio0.49577928
137MP0009384_cardiac_valve_regurgitation0.48794942
138MP0002229_neurodegeneration0.48778810
139MP0003123_paternal_imprinting0.48544455
140MP0002233_abnormal_nose_morphology0.47933903
141MP0003938_abnormal_ear_development0.47731177
142MP0002132_abnormal_respiratory_system0.47716402
143MP0004147_increased_porphyrin_level0.47650275
144MP0003763_abnormal_thymus_physiology0.47605615
145MP0000350_abnormal_cell_proliferation0.46697735
146MP0002752_abnormal_somatic_nervous0.46377540
147MP0005595_abnormal_vascular_smooth0.46247856
148MP0000026_abnormal_inner_ear0.45822222
149MP0000631_abnormal_neuroendocrine_gland0.45370737
150MP0003861_abnormal_nervous_system0.44338242
151MP0009250_abnormal_appendicular_skeleto0.44141429
152MP0002085_abnormal_embryonic_tissue0.43620457
153MP0005551_abnormal_eye_electrophysiolog0.43152538
154MP0010678_abnormal_skin_adnexa0.43018676
155MP0000490_abnormal_crypts_of0.42837656
156MP0001968_abnormal_touch/_nociception0.42455868
157MP0001730_embryonic_growth_arrest0.42455678
158MP0005253_abnormal_eye_physiology0.41822145
159MP0001963_abnormal_hearing_physiology0.41504458
160MP0003121_genomic_imprinting0.41057656
161MP0004264_abnormal_extraembryonic_tissu0.40463415
162MP0001502_abnormal_circadian_rhythm0.40298666
163MP0008995_early_reproductive_senescence0.40132840
164MP0001764_abnormal_homeostasis0.38641855
165MP0003786_premature_aging0.38126410
166MP0002405_respiratory_system_inflammati0.37042850
167MP0010307_abnormal_tumor_latency0.36967767
168MP0002163_abnormal_gland_morphology0.36943722
169MP0000015_abnormal_ear_pigmentation0.36693504
170MP0000313_abnormal_cell_death0.36287577
171MP0001346_abnormal_lacrimal_gland0.36016023
172MP0003315_abnormal_perineum_morphology0.34887249
173MP0000703_abnormal_thymus_morphology0.34600706
174MP0002734_abnormal_mechanical_nocicepti0.33877911

Predicted human phenotypes

RankGene SetZ-score
1Abnormal ciliary motility (HP:0012262)9.55947846
2Abnormal respiratory motile cilium morphology (HP:0005938)9.02302550
3Abnormal respiratory epithelium morphology (HP:0012253)9.02302550
4Rhinitis (HP:0012384)8.22862792
5Chronic bronchitis (HP:0004469)7.06519399
6Infertility (HP:0000789)5.92745250
7Male infertility (HP:0003251)5.24923276
8Bronchiectasis (HP:0002110)5.22800520
9Nasal polyposis (HP:0100582)5.09273281
10Abnormality of the nasal mucosa (HP:0000433)3.95905363
11Bronchitis (HP:0012387)3.83965379
12Nephronophthisis (HP:0000090)3.67666456
13Recurrent sinusitis (HP:0011108)3.54650426
14Chronic otitis media (HP:0000389)3.34852242
15Pancreatic fibrosis (HP:0100732)3.02302243
16Molar tooth sign on MRI (HP:0002419)2.95740994
17Abnormality of midbrain morphology (HP:0002418)2.95740994
18Recurrent otitis media (HP:0000403)2.89084741
19Abnormality of the renal medulla (HP:0100957)2.84547339
20Abnormal spermatogenesis (HP:0008669)2.75388224
21Chronic hepatic failure (HP:0100626)2.69704854
22Medial flaring of the eyebrow (HP:0010747)2.67216590
23True hermaphroditism (HP:0010459)2.49361634
24Tubulointerstitial nephritis (HP:0001970)2.46469430
25Supernumerary spleens (HP:0009799)2.46214116
26Atelectasis (HP:0100750)2.43439970
27Chromsome breakage (HP:0040012)2.37244520
28Chronic sinusitis (HP:0011109)2.19891522
29Anencephaly (HP:0002323)2.18775327
30Postaxial foot polydactyly (HP:0001830)2.17096695
31Chromosomal breakage induced by crosslinking agents (HP:0003221)2.15196587
32Absent rod-and cone-mediated responses on ERG (HP:0007688)2.03561585
33Impulsivity (HP:0100710)2.02714702
34Pancreatic cysts (HP:0001737)2.00578798
35Congenital primary aphakia (HP:0007707)2.00343982
36Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.7381260
37Absent/shortened dynein arms (HP:0200106)10.9495653
38Dynein arm defect of respiratory motile cilia (HP:0012255)10.9495653
39Abnormal respiratory motile cilium physiology (HP:0012261)10.6922574
40Gait imbalance (HP:0002141)1.98390694
41Congenital hepatic fibrosis (HP:0002612)1.98354737
42Azoospermia (HP:0000027)1.94520419
43Cystic liver disease (HP:0006706)1.93334197
44Asplenia (HP:0001746)1.91705813
45Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.86850988
46Absent frontal sinuses (HP:0002688)1.85949958
47Acute myeloid leukemia (HP:0004808)1.81851209
48Aplasia/Hypoplasia of the spleen (HP:0010451)1.81630197
49Aplasia/Hypoplasia of the tongue (HP:0010295)1.80644770
50Abnormality of abdominal situs (HP:0011620)1.80593779
51Abdominal situs inversus (HP:0003363)1.80593779
52Furrowed tongue (HP:0000221)1.77090700
53Occipital encephalocele (HP:0002085)1.76961103
54Hyperactive renin-angiotensin system (HP:0000841)1.76837063
55Abnormal biliary tract physiology (HP:0012439)1.76690971
56Bile duct proliferation (HP:0001408)1.76690971
57Acute lymphatic leukemia (HP:0006721)1.70250958
58Poor coordination (HP:0002370)1.69195696
59Recurrent bronchitis (HP:0002837)1.68929365
60Nephrogenic diabetes insipidus (HP:0009806)1.68361266
61Genital tract atresia (HP:0001827)1.66197455
62Stage 5 chronic kidney disease (HP:0003774)1.65510301
63Tubulointerstitial abnormality (HP:0001969)1.63942854
64Tubular atrophy (HP:0000092)1.63324487
65Median cleft lip (HP:0000161)1.63125774
66Nephropathy (HP:0000112)1.63117057
67Vaginal atresia (HP:0000148)1.60202505
68Aplasia/Hypoplasia of the lens (HP:0008063)1.59262565
69Bell-shaped thorax (HP:0001591)1.57787369
70Abnormality of the dental root (HP:0006486)1.56889558
71Taurodontia (HP:0000679)1.56889558
72Abnormality of permanent molar morphology (HP:0011071)1.56889558
73Male pseudohermaphroditism (HP:0000037)1.56591550
74Postaxial hand polydactyly (HP:0001162)1.56359239
75Dyschromatopsia (HP:0007641)1.54753197
76Abnormality of B cell number (HP:0010975)1.50516482
77B lymphocytopenia (HP:0010976)1.50516482
78Cholecystitis (HP:0001082)1.49536721
79Abnormal gallbladder physiology (HP:0012438)1.49536721
80Abnormality of the frontal sinuses (HP:0002687)1.48636671
81Nephroblastoma (Wilms tumor) (HP:0002667)1.48399139
82Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.46814309
83Hypoplasia of the capital femoral epiphysis (HP:0003090)1.45951006
84Decreased central vision (HP:0007663)1.45439587
85Optic nerve hypoplasia (HP:0000609)1.44552886
86Oculomotor apraxia (HP:0000657)1.44294011
87Papillary thyroid carcinoma (HP:0002895)1.43961695
88Abnormality of molar morphology (HP:0011070)1.43354551
89Abnormality of molar (HP:0011077)1.43354551
90Optic neuritis (HP:0100653)1.43216440
91Retrobulbar optic neuritis (HP:0100654)1.43216440
92Oligodactyly (hands) (HP:0001180)1.42829448
93Embryonal renal neoplasm (HP:0011794)1.40989277
94Cone-rod dystrophy (HP:0000548)1.40401671
95Abnormality of the dental pulp (HP:0006479)1.39973765
96Abnormality of macular pigmentation (HP:0008002)1.39332834
97Preaxial hand polydactyly (HP:0001177)1.39272209
98Short ribs (HP:0000773)1.38660636
99Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.37354003
100Aplasia/Hypoplasia of the uvula (HP:0010293)1.37245027
101Broad distal phalanx of finger (HP:0009836)1.36375473
102Ventricular fibrillation (HP:0001663)1.36131823
103Abnormal drinking behavior (HP:0030082)1.35759908
104Polydipsia (HP:0001959)1.35759908
105Sloping forehead (HP:0000340)1.35708248
106Facial cleft (HP:0002006)1.35682964
107Pulmonary fibrosis (HP:0002206)1.34799368
108Hip dysplasia (HP:0001385)1.34527067
109Abnormality of the renal cortex (HP:0011035)1.34205229
110Abnormal rod and cone electroretinograms (HP:0008323)1.33383513
111Decreased circulating renin level (HP:0003351)1.30658358
112Type 2 muscle fiber atrophy (HP:0003554)1.28190810
113Prolonged bleeding time (HP:0003010)1.27867630
114Abnormality of dentin (HP:0010299)1.25686638
115Anophthalmia (HP:0000528)1.24286219
116Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.24174756
117Constricted visual fields (HP:0001133)1.23397616
118Abnormality of chromosome stability (HP:0003220)1.21549059
119Sclerocornea (HP:0000647)1.19776888
120Abnormality of the preputium (HP:0100587)1.19776753
121Renal dysplasia (HP:0000110)1.19620699
122Abnormal lung lobation (HP:0002101)1.19261080
123Meckel diverticulum (HP:0002245)1.19184460
124Abnormality of lateral ventricle (HP:0030047)1.17116376
125Papilledema (HP:0001085)1.15938315
126Portal hypertension (HP:0001409)1.14205216
127Prominent nasal bridge (HP:0000426)1.12170081
128Narrow forehead (HP:0000341)1.10699077
129Renal salt wasting (HP:0000127)1.10146743
130Hypokalemic alkalosis (HP:0001949)1.05470359
131Aganglionic megacolon (HP:0002251)1.04617585
132Hyperkalemia (HP:0002153)1.03775140
133Hyperaldosteronism (HP:0000859)1.01888626
134Abnormality of the hepatic vasculature (HP:0006707)1.00922093
135Purpura (HP:0000979)0.99616416
136Vertebral hypoplasia (HP:0008417)0.98510591
137Aplasia/Hypoplasia of the vertebrae (HP:0008515)0.98510591
138Degeneration of the lateral corticospinal tracts (HP:0002314)0.97698380

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK47.27429914
2PDK37.27429914
3MAP4K24.76592250
4PDK24.33654681
5PRKD33.41874957
6TESK13.39586993
7TSSK63.20460729
8MAP3K62.72796548
9MST42.23650521
10MUSK2.20035978
11PLK42.03660442
12TTK2.02951836
13KIT2.00965614
14STK38L1.99477271
15ICK1.94368254
16NEK21.93990354
17PNCK1.92137959
18LATS11.83890587
19BRAF1.80752281
20STK391.79186409
21TAF11.66270536
22LATS21.66076765
23CDC71.62240248
24ERBB41.54138335
25TAOK31.51034017
26CHEK21.48871179
27EEF2K1.44939292
28CSF1R1.42927756
29TIE11.36478317
30FLT31.35758983
31STK381.34290757
32TLK11.27321082
33WNK41.27148406
34STK101.23990472
35FES1.20556979
36STK31.17605910
37MAPK151.14795614
38ARAF1.14765615
39INSRR1.14633375
40RIPK41.10186767
41MOS1.00054263
42PLK10.97322848
43PDK10.95805543
44PTK2B0.95417386
45MATK0.95176370
46MAP2K70.94287606
47DYRK30.89224304
48MAP3K70.87013047
49TGFBR10.86989662
50MKNK10.86505323
51EPHA20.86291162
52TBK10.85162350
53MAP3K130.82581074
54MAPKAPK50.79909477
55BUB10.78567030
56CAMKK20.75391272
57CSK0.73372607
58WEE10.73034212
59MAP3K40.72951524
60KSR20.72828349
61CAMKK10.71629371
62GRK60.71549908
63STK160.71353682
64RAF10.67088609
65BTK0.66851606
66LMTK20.64880409
67NTRK20.64596006
68MAP3K90.63473375
69CHEK10.62216067
70TEC0.62002395
71BCKDK0.60456710
72AURKA0.60352325
73ADRBK20.59707096
74EIF2AK10.59582970
75MAP3K20.59251577
76RPS6KB20.58382923
77PLK30.57982244
78LRRK20.57621214
79ATM0.56996949
80CDK30.55561433
81CDK90.55208626
82CDK60.55184464
83VRK10.53213614
84ATR0.53165707
85TYRO30.52631569
86MAP2K20.52455783
87WNK10.51126388
88CDK80.49651847
89MELK0.48932699
90DAPK20.48852155
91MAPK130.48725486
92BRSK20.48703156
93PASK0.48348419
94SYK0.48280095
95BMPR1B0.46989632
96NEK90.46832575
97MAP3K50.46397165
98MAP3K80.42880219
99HIPK20.42585943
100AURKB0.42173828
101DYRK20.41522325
102LYN0.41227801
103TNK20.40640322
104MAP2K60.40329973
105CDK190.39925145
106ADRBK10.39472712
107ITK0.38714160
108IRAK10.38489588
109NME10.38460202
110PDPK10.38044533
111MAPKAPK30.37258078
112MAP3K10.36921328
113RPS6KA50.36825297
114ABL20.36681632
115PAK10.35812676
116ACVR1B0.34852477
117MAP4K10.34503892
118NUAK10.32509902
119TESK20.32262814
120SRPK10.31387658
121EPHA30.31101130
122PRKAA10.31091752
123PRKCD0.30048538
124PAK60.29401626
125DYRK1B0.29075596
126DYRK1A0.29065055
127RPS6KA60.28536137
128PRKD10.28149694
129HCK0.27864912
130JAK30.27606566
131TAOK10.27225781
132PLK20.25210106
133TNIK0.24274073
134TRPM70.24179047
135BRSK10.24139124
136EPHB10.24011678
137PINK10.23229831
138ERBB30.23066878
139CDK150.23018141
140ZAP700.22799117
141MAP2K40.22732170
142MAPK40.22065032
143FRK0.21939007
144PIM20.21704135
145CSNK1G20.21357590
146CDK180.21229033
147VRK20.20988559
148PRKCQ0.20689573
149PRKD20.20191540
150CDK10.19857957
151CAMK2A0.18955382
152TXK0.18592867
153LCK0.18428918
154PRKAA20.17911576
155CCNB10.17851666
156IGF1R0.17747740
157IKBKE0.17372245
158CDK11A0.17191409
159ABL10.16847729
160NLK0.16698960
161PRKCA0.16484294
162MAPK70.16200490
163EIF2AK20.15951893
164OXSR10.15845823
165BMPR20.15285015
166RPS6KB10.15021392
167NEK60.14544210
168MAPK30.14033382

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.56005986
2Basal transcription factors_Homo sapiens_hsa030223.77167446
3Chemical carcinogenesis_Homo sapiens_hsa052043.61267241
4Linoleic acid metabolism_Homo sapiens_hsa005913.11973556
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.04637395
6Fanconi anemia pathway_Homo sapiens_hsa034602.90128408
7Cell cycle_Homo sapiens_hsa041102.86535213
8Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.77266915
9Ether lipid metabolism_Homo sapiens_hsa005652.68870508
10Pyruvate metabolism_Homo sapiens_hsa006202.51414819
11Oocyte meiosis_Homo sapiens_hsa041142.44939593
12Non-homologous end-joining_Homo sapiens_hsa034502.42605783
13Homologous recombination_Homo sapiens_hsa034402.40910570
14Phenylalanine metabolism_Homo sapiens_hsa003602.33657654
15beta-Alanine metabolism_Homo sapiens_hsa004102.26659474
16Dorso-ventral axis formation_Homo sapiens_hsa043202.24918054
17Fatty acid biosynthesis_Homo sapiens_hsa000612.10596170
18Glycosaminoglycan degradation_Homo sapiens_hsa005312.10325090
19Tyrosine metabolism_Homo sapiens_hsa003502.04943872
20RNA degradation_Homo sapiens_hsa030181.95525712
21Salivary secretion_Homo sapiens_hsa049701.92353162
22Retinol metabolism_Homo sapiens_hsa008301.78327503
23Ovarian steroidogenesis_Homo sapiens_hsa049131.76295544
24Caffeine metabolism_Homo sapiens_hsa002321.71813410
25Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.64174641
26ABC transporters_Homo sapiens_hsa020101.63649918
27Purine metabolism_Homo sapiens_hsa002301.61717028
28Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.59531860
29Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.54098524
30Butanoate metabolism_Homo sapiens_hsa006501.50528333
31DNA replication_Homo sapiens_hsa030301.49403082
32Glucagon signaling pathway_Homo sapiens_hsa049221.46991687
33Asthma_Homo sapiens_hsa053101.45876806
34Propanoate metabolism_Homo sapiens_hsa006401.45090089
35Pentose phosphate pathway_Homo sapiens_hsa000301.40380687
36Glycerophospholipid metabolism_Homo sapiens_hsa005641.40356961
37Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.38839616
38RNA transport_Homo sapiens_hsa030131.36333525
39Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.33902353
40Steroid hormone biosynthesis_Homo sapiens_hsa001401.31163301
41Peroxisome_Homo sapiens_hsa041461.31148311
42Transcriptional misregulation in cancer_Homo sapiens_hsa052021.30327995
43Base excision repair_Homo sapiens_hsa034101.28226981
44Nucleotide excision repair_Homo sapiens_hsa034201.27431353
45Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.26446432
46Mismatch repair_Homo sapiens_hsa034301.25612228
47Glutathione metabolism_Homo sapiens_hsa004801.24558867
48Hematopoietic cell lineage_Homo sapiens_hsa046401.23092391
49Pyrimidine metabolism_Homo sapiens_hsa002401.18721352
50Glycerolipid metabolism_Homo sapiens_hsa005611.17972947
51Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.16075728
52Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.15231025
53Huntingtons disease_Homo sapiens_hsa050161.14820133
54Nitrogen metabolism_Homo sapiens_hsa009101.12704050
55Arachidonic acid metabolism_Homo sapiens_hsa005901.11692016
56Carbohydrate digestion and absorption_Homo sapiens_hsa049731.10353613
57Other glycan degradation_Homo sapiens_hsa005111.10301364
58Platelet activation_Homo sapiens_hsa046111.09118086
59Intestinal immune network for IgA production_Homo sapiens_hsa046721.07732046
60Inositol phosphate metabolism_Homo sapiens_hsa005621.07181036
61mRNA surveillance pathway_Homo sapiens_hsa030151.06454394
62Notch signaling pathway_Homo sapiens_hsa043301.02395583
63Maturity onset diabetes of the young_Homo sapiens_hsa049501.01327394
64Sphingolipid metabolism_Homo sapiens_hsa006000.98515105
65Amphetamine addiction_Homo sapiens_hsa050310.97163458
66Taste transduction_Homo sapiens_hsa047420.96027288
67Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.92263911
68African trypanosomiasis_Homo sapiens_hsa051430.92011959
69Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.90396220
70Starch and sucrose metabolism_Homo sapiens_hsa005000.88961979
71p53 signaling pathway_Homo sapiens_hsa041150.87726715
72Circadian rhythm_Homo sapiens_hsa047100.82904692
73Legionellosis_Homo sapiens_hsa051340.81246785
74Phosphatidylinositol signaling system_Homo sapiens_hsa040700.81209352
75Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.81145207
76Fatty acid degradation_Homo sapiens_hsa000710.80717975
77Antigen processing and presentation_Homo sapiens_hsa046120.78841579
78Allograft rejection_Homo sapiens_hsa053300.78214901
79Cysteine and methionine metabolism_Homo sapiens_hsa002700.78170954
80NOD-like receptor signaling pathway_Homo sapiens_hsa046210.77534420
81Rheumatoid arthritis_Homo sapiens_hsa053230.77396905
82Type I diabetes mellitus_Homo sapiens_hsa049400.74440413
83Estrogen signaling pathway_Homo sapiens_hsa049150.73402194
84Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.72522674
85Hedgehog signaling pathway_Homo sapiens_hsa043400.71580707
86SNARE interactions in vesicular transport_Homo sapiens_hsa041300.70963963
87Drug metabolism - other enzymes_Homo sapiens_hsa009830.70517127
88Malaria_Homo sapiens_hsa051440.68187805
89Primary bile acid biosynthesis_Homo sapiens_hsa001200.68035392
90Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.68034379
91Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.67580538
92Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.66712759
93Tryptophan metabolism_Homo sapiens_hsa003800.65108216
94Primary immunodeficiency_Homo sapiens_hsa053400.64972897
95Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.62351384
96Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.61530547
97Leishmaniasis_Homo sapiens_hsa051400.59898952
98Thyroid hormone synthesis_Homo sapiens_hsa049180.58079567
99Regulation of autophagy_Homo sapiens_hsa041400.57958612
100Staphylococcus aureus infection_Homo sapiens_hsa051500.57808440
101Leukocyte transendothelial migration_Homo sapiens_hsa046700.57547251
102Autoimmune thyroid disease_Homo sapiens_hsa053200.57425657
103Mineral absorption_Homo sapiens_hsa049780.56855210
104Graft-versus-host disease_Homo sapiens_hsa053320.56854151
105Lysosome_Homo sapiens_hsa041420.56751515
106Serotonergic synapse_Homo sapiens_hsa047260.56556568
107Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.56171341
108Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.56156830
109Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.56007194
110cAMP signaling pathway_Homo sapiens_hsa040240.54724343
111RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.53814332
112Pancreatic secretion_Homo sapiens_hsa049720.53077738
113Circadian entrainment_Homo sapiens_hsa047130.52362959
114Vitamin digestion and absorption_Homo sapiens_hsa049770.52197013
115Thyroid hormone signaling pathway_Homo sapiens_hsa049190.49557545
116Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.48595945
117Basal cell carcinoma_Homo sapiens_hsa052170.46892322
118RNA polymerase_Homo sapiens_hsa030200.46074747
119GnRH signaling pathway_Homo sapiens_hsa049120.45404252
120Complement and coagulation cascades_Homo sapiens_hsa046100.43399564
121Nicotine addiction_Homo sapiens_hsa050330.43121234
122Tight junction_Homo sapiens_hsa045300.41574256
123Choline metabolism in cancer_Homo sapiens_hsa052310.40937828
124Vascular smooth muscle contraction_Homo sapiens_hsa042700.40169326
125VEGF signaling pathway_Homo sapiens_hsa043700.37956811
126Metabolic pathways_Homo sapiens_hsa011000.37394831
127Sulfur metabolism_Homo sapiens_hsa009200.36517751
128Alcoholism_Homo sapiens_hsa050340.35409541
129Jak-STAT signaling pathway_Homo sapiens_hsa046300.35013845
130Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.34907878
131Epstein-Barr virus infection_Homo sapiens_hsa051690.34399294
132Influenza A_Homo sapiens_hsa051640.33798764
133cGMP-PKG signaling pathway_Homo sapiens_hsa040220.33731825
134GABAergic synapse_Homo sapiens_hsa047270.33388102
135Calcium signaling pathway_Homo sapiens_hsa040200.31826038
136Wnt signaling pathway_Homo sapiens_hsa043100.30035786
137Selenocompound metabolism_Homo sapiens_hsa004500.29696166
138Pancreatic cancer_Homo sapiens_hsa052120.29669417
139Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.28371263
140Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.28236793
141Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.27384660
142Viral carcinogenesis_Homo sapiens_hsa052030.27193765
143Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.26493977
144T cell receptor signaling pathway_Homo sapiens_hsa046600.26000403
145Systemic lupus erythematosus_Homo sapiens_hsa053220.25965075
146Herpes simplex infection_Homo sapiens_hsa051680.25741727
147Insulin secretion_Homo sapiens_hsa049110.25055563
148Glutamatergic synapse_Homo sapiens_hsa047240.24334062
149TGF-beta signaling pathway_Homo sapiens_hsa043500.23329457
150Long-term potentiation_Homo sapiens_hsa047200.22876749
151Protein export_Homo sapiens_hsa030600.22076593
152Renin secretion_Homo sapiens_hsa049240.21313726
153Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.19410615
154Fructose and mannose metabolism_Homo sapiens_hsa000510.17948210
155PPAR signaling pathway_Homo sapiens_hsa033200.17795104
156Carbon metabolism_Homo sapiens_hsa012000.17139826
157MAPK signaling pathway_Homo sapiens_hsa040100.17130955
158Olfactory transduction_Homo sapiens_hsa047400.16994021
159Endocytosis_Homo sapiens_hsa041440.16491219
160Phototransduction_Homo sapiens_hsa047440.15945766
161Histidine metabolism_Homo sapiens_hsa003400.15693123
162Biosynthesis of amino acids_Homo sapiens_hsa012300.13583254
163Cocaine addiction_Homo sapiens_hsa050300.13079828
164Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.12987486

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