ARCHS4

Functional Annotation Prediction

Predicted biological processes (GO)

Rank	Gene Set	Z-score
1	axonemal dynein complex assembly (GO:0070286)	5.65099531
2	mitochondrial ATP synthesis coupled proton transport (GO:0042776)	5.62352669
3	energy coupled proton transport, down electrochemical gradient (GO:0015985)	5.42592531
4	ATP synthesis coupled proton transport (GO:0015986)	5.42592531
5	mitochondrial electron transport, NADH to ubiquinone (GO:0006120)	5.37652401
6	cilium or flagellum-dependent cell motility (GO:0001539)	5.28179463
7	GTP biosynthetic process (GO:0006183)	5.09098906
8	cilium movement (GO:0003341)	5.07186893
9	protein neddylation (GO:0045116)	4.96434966
10	epithelial cilium movement (GO:0003351)	4.92938947
11	respiratory electron transport chain (GO:0022904)	4.39337181
12	electron transport chain (GO:0022900)	4.34938677
13	intraciliary transport (GO:0042073)	4.22257436
14	regulation of cilium movement (GO:0003352)	4.18898628
15	UTP biosynthetic process (GO:0006228)	4.16075962
16	acrosome assembly (GO:0001675)	4.13941181
17	multicellular organism reproduction (GO:0032504)	4.13684185
18	protein localization to cilium (GO:0061512)	4.13132265
19	behavioral response to nicotine (GO:0035095)	4.10534047
20	epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)	4.06052861
21	protein complex biogenesis (GO:0070271)	4.05136325
22	pyrimidine nucleobase catabolic process (GO:0006208)	3.99658371
23	chaperone-mediated protein transport (GO:0072321)	3.99056503
24	mitochondrial respiratory chain complex I biogenesis (GO:0097031)	3.98868631
25	mitochondrial respiratory chain complex I assembly (GO:0032981)	3.98868631
26	NADH dehydrogenase complex assembly (GO:0010257)	3.98868631
27	cell wall macromolecule catabolic process (GO:0016998)	3.95523555
28	cell wall macromolecule metabolic process (GO:0044036)	3.95523555
29	guanosine-containing compound biosynthetic process (GO:1901070)	3.89777398
30	axon ensheathment in central nervous system (GO:0032291)	3.86847634
31	central nervous system myelination (GO:0022010)	3.86847634
32	nonmotile primary cilium assembly (GO:0035058)	3.79375182
33	sperm motility (GO:0030317)	3.73981867
34	fusion of sperm to egg plasma membrane (GO:0007342)	3.72592100
35	motile cilium assembly (GO:0044458)	3.69659245
36	mitochondrial respiratory chain complex assembly (GO:0033108)	3.67528132
37	establishment of protein localization to mitochondrial membrane (GO:0090151)	3.60405497
38	sperm-egg recognition (GO:0035036)	3.58692674
39	nucleoside diphosphate phosphorylation (GO:0006165)	3.57731745
40	UTP metabolic process (GO:0046051)	3.49854821
41	purine ribonucleoside triphosphate biosynthetic process (GO:0009206)	3.49389697
42	acrosome reaction (GO:0007340)	3.45792314
43	translational elongation (GO:0006414)	3.44577997
44	axoneme assembly (GO:0035082)	3.41901736
45	purine nucleoside triphosphate biosynthetic process (GO:0009145)	3.38089848
46	cullin deneddylation (GO:0010388)	3.35573253
47	CTP biosynthetic process (GO:0006241)	3.33694435
48	CTP metabolic process (GO:0046036)	3.33694435
49	ribosomal small subunit biogenesis (GO:0042274)	3.29962620
50	neuron fate determination (GO:0048664)	3.27048820
51	cellular protein complex disassembly (GO:0043624)	3.25673273
52	hydrogen ion transmembrane transport (GO:1902600)	3.25264470
53	nucleobase catabolic process (GO:0046113)	3.21135901
54	spermatid nucleus differentiation (GO:0007289)	3.19083313
55	left/right pattern formation (GO:0060972)	3.17978439
56	long-chain fatty acid biosynthetic process (GO:0042759)	3.17976549
57	ventricular system development (GO:0021591)	3.16297978
58	centriole replication (GO:0007099)	3.12527985
59	viral life cycle (GO:0019058)	3.12230031
60	maturation of SSU-rRNA (GO:0030490)	3.10819765
61	pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)	3.06117613
62	RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)	3.05821556
63	tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)	3.05821556
64	cell-cell recognition (GO:0009988)	3.05267201
65	binding of sperm to zona pellucida (GO:0007339)	3.03815348
66	ATP biosynthetic process (GO:0006754)	3.03758494
67	male meiosis (GO:0007140)	2.99360331
68	cotranslational protein targeting to membrane (GO:0006613)	2.98489526
69	ribonucleoside triphosphate biosynthetic process (GO:0009201)	2.95782318
70	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)	2.94880703
71	proton transport (GO:0015992)	2.94865564
72	single fertilization (GO:0007338)	2.94167717
73	respiratory chain complex IV assembly (GO:0008535)	2.93404904
74	mannosylation (GO:0097502)	2.93362254
75	protein deneddylation (GO:0000338)	2.92540212
76	sperm capacitation (GO:0048240)	2.91236242
77	RNA capping (GO:0036260)	2.89427144
78	7-methylguanosine RNA capping (GO:0009452)	2.89427144
79	establishment of integrated proviral latency (GO:0075713)	2.89245363
80	reproduction (GO:0000003)	2.89219755
81	cilium assembly (GO:0042384)	2.88554795
82	SRP-dependent cotranslational protein targeting to membrane (GO:0006614)	2.88051071
83	ribosomal small subunit assembly (GO:0000028)	2.88036718
84	protein targeting to ER (GO:0045047)	2.87868226
85	cilium organization (GO:0044782)	2.87139261
86	hydrogen transport (GO:0006818)	2.86352944
87	positive regulation of mitochondrial fission (GO:0090141)	2.85964082
88	viral transcription (GO:0019083)	2.84267278
89	7-methylguanosine mRNA capping (GO:0006370)	2.84191275
90	retinal ganglion cell axon guidance (GO:0031290)	2.83270045
91	neutrophil activation involved in immune response (GO:0002283)	2.83043157
92	cytochrome complex assembly (GO:0017004)	2.82553816
93	cilium morphogenesis (GO:0060271)	2.81314118
94	protein-cofactor linkage (GO:0018065)	2.80479026
95	transcription elongation from RNA polymerase III promoter (GO:0006385)	2.79430870
96	termination of RNA polymerase III transcription (GO:0006386)	2.79430870
97	protein complex disassembly (GO:0043241)	2.79207874
98	protein localization to endoplasmic reticulum (GO:0070972)	2.79085902
99	spermatid development (GO:0007286)	2.78902070
100	platelet dense granule organization (GO:0060155)	2.78817050
101	neuron cell-cell adhesion (GO:0007158)	2.78574663
102	plasma membrane fusion (GO:0045026)	2.77548758
103	presynaptic membrane assembly (GO:0097105)	2.77541658
104	pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)	2.77171241
105	inner mitochondrial membrane organization (GO:0007007)	2.76213627
106	protein polyglutamylation (GO:0018095)	2.75069034
107	sequestering of actin monomers (GO:0042989)	2.73448007
108	establishment of protein localization to endoplasmic reticulum (GO:0072599)	2.72775420
109	translational initiation (GO:0006413)	2.72330198
110	macromolecular complex disassembly (GO:0032984)	2.71595211
111	intracellular protein transmembrane import (GO:0044743)	2.70985056
112	translational termination (GO:0006415)	2.70590224
113	nucleoside triphosphate biosynthetic process (GO:0009142)	2.69309006
114	presynaptic membrane organization (GO:0097090)	2.69052504
115	chromatin remodeling at centromere (GO:0031055)	2.68967661
116	establishment of viral latency (GO:0019043)	2.65750283
117	resolution of meiotic recombination intermediates (GO:0000712)	2.65705719
118	ATP hydrolysis coupled proton transport (GO:0015991)	2.64959051
119	energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)	2.64959051
120	proteasome assembly (GO:0043248)	2.64851950
121	somite development (GO:0061053)	2.63858137
122	GPI anchor biosynthetic process (GO:0006506)	2.63821411
123	dopamine transport (GO:0015872)	2.63360191
124	substrate-independent telencephalic tangential interneuron migration (GO:0021843)	2.62710747
125	substrate-independent telencephalic tangential migration (GO:0021826)	2.62710747
126	nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)	2.61322307
127	microtubule depolymerization (GO:0007019)	2.61049796
128	pyrimidine nucleoside triphosphate metabolic process (GO:0009147)	2.60440555
129	ubiquinone metabolic process (GO:0006743)	2.60231445
130	smoothened signaling pathway (GO:0007224)	2.58946228
131	postsynaptic membrane organization (GO:0001941)	2.54779012
132	transmission of nerve impulse (GO:0019226)	2.54298567
133	positive regulation of gastrulation (GO:2000543)	2.54010000
134	organelle disassembly (GO:1903008)	2.53574445
135	translation (GO:0006412)	2.53502212
136	cell proliferation in forebrain (GO:0021846)	2.52583615
137	DNA damage response, detection of DNA damage (GO:0042769)	2.52413677
138	pyrimidine deoxyribonucleotide catabolic process (GO:0009223)	2.51476243
139	regulation of microtubule-based movement (GO:0060632)	2.51367796
140	ubiquinone biosynthetic process (GO:0006744)	2.51252538
141	regulation of mitochondrial translation (GO:0070129)	2.51077664
142	water-soluble vitamin biosynthetic process (GO:0042364)	2.48544479
143	negative regulation of transcription regulatory region DNA binding (GO:2000678)	2.47141596
144	left/right axis specification (GO:0070986)	2.47071896

Predicted upstream transcription factors (ChEA)

Rank	Gene Set	Z-score
1	TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse	3.91413038
2	EZH2_22144423_ChIP-Seq_EOC_Human	3.31349026
3	SOX9_22984422_ChIP-ChIP_TESTIS_Rat	3.23132450
4	BP1_19119308_ChIP-ChIP_Hs578T_Human	3.17890408
5	CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human	3.11097768
6	VDR_22108803_ChIP-Seq_LS180_Human	2.68577224
7	GBX2_23144817_ChIP-Seq_PC3_Human	2.58761300
8	HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse	2.57409460
9	GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse	2.48005493
10	ZFP57_27257070_Chip-Seq_ESCs_Mouse	2.46920227
11	TAF15_26573619_Chip-Seq_HEK293_Human	2.45602348
12	KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human	2.38289080
13	GABP_17652178_ChIP-ChIP_JURKAT_Human	2.28065455
14	EST1_17652178_ChIP-ChIP_JURKAT_Human	2.16769403
15	CBX2_27304074_Chip-Seq_ESCs_Mouse	2.07813702
16	HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human	2.06469699
17	BMI1_23680149_ChIP-Seq_NPCS_Mouse	2.05154166
18	PCGF2_27294783_Chip-Seq_ESCs_Mouse	2.04626954
19	TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat	2.03558510
20	POU3F2_20337985_ChIP-ChIP_501MEL_Human	2.00971014
21	FUS_26573619_Chip-Seq_HEK293_Human	2.00597712
22	FLI1_27457419_Chip-Seq_LIVER_Mouse	1.99019862
23	CTBP2_25329375_ChIP-Seq_LNCAP_Human	1.98818754
24	RNF2_27304074_Chip-Seq_NSC_Mouse	1.89247367
25	IGF1R_20145208_ChIP-Seq_DFB_Human	1.86743217
26	* ER_23166858_ChIP-Seq_MCF-7_Human	1.81005088
27	MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse	1.76183276
28	P300_19829295_ChIP-Seq_ESCs_Human	1.74668695
29	E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse	1.72518091
30	CTBP1_25329375_ChIP-Seq_LNCAP_Human	1.69842019
31	HCFC1_20581084_ChIP-Seq_MESCs_Mouse	1.63440459
32	CHD1_19587682_ChIP-ChIP_MESCs_Mouse	1.61518136
33	MYCN_21190229_ChIP-Seq_SHEP-21N_Human	1.59970105
34	MYC_18940864_ChIP-ChIP_HL60_Human	1.57602027
35	JARID1A_20064375_ChIP-Seq_MESCs_Mouse	1.56356309
36	RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse	1.56102209
37	NOTCH1_17114293_ChIP-ChIP_T-ALL_Human	1.53886205
38	EWS_26573619_Chip-Seq_HEK293_Human	1.51689098
39	NANOG_18555785_Chip-Seq_ESCs_Mouse	1.49719931
40	EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse	1.48529930
41	CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons	1.45825678
42	TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse	1.41685990
43	SUZ12_18555785_Chip-Seq_ESCs_Mouse	1.40681043
44	FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse	1.40514185
45	PDX1_19855005_ChIP-ChIP_MIN6_Mouse	1.39989403
46	SRF_21415370_ChIP-Seq_HL-1_Mouse	1.39988461
47	P53_22387025_ChIP-Seq_ESCs_Mouse	1.39935661
48	GLI1_17442700_ChIP-ChIP_MESCs_Mouse	1.36722104
49	CMYC_18555785_Chip-Seq_ESCs_Mouse	1.36564289
50	STAT3_18555785_Chip-Seq_ESCs_Mouse	1.36336406
51	ELK1_19687146_ChIP-ChIP_HELA_Human	1.34346436
52	P300_18555785_Chip-Seq_ESCs_Mouse	1.31994257
53	IRF1_19129219_ChIP-ChIP_H3396_Human	1.31643216
54	TAL1_26923725_Chip-Seq_HPCs_Mouse	1.31559262
55	EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse	1.31302378
56	E2F1_18555785_Chip-Seq_ESCs_Mouse	1.30350144
57	OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse	1.28373529
58	SUZ12_27294783_Chip-Seq_NPCs_Mouse	1.27516132
59	NFE2_27457419_Chip-Seq_LIVER_Mouse	1.23197695
60	TOP2B_26459242_ChIP-Seq_MCF-7_Human	1.22488877
61	GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse	1.22163427
62	ETS1_20019798_ChIP-Seq_JURKAT_Human	1.21770005
63	SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse	1.21642688
64	UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human	1.21496423
65	EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human	1.21362809
66	TP53_22573176_ChIP-Seq_HFKS_Human	1.21206641
67	SOX2_18555785_Chip-Seq_ESCs_Mouse	1.20660102
68	SOX2_16153702_ChIP-ChIP_HESCs_Human	1.20659537
69	EED_16625203_ChIP-ChIP_MESCs_Mouse	1.19453667
70	PCGF2_27294783_Chip-Seq_NPCs_Mouse	1.19407860
71	RUNX1_27457419_Chip-Seq_LIVER_Mouse	1.19010480
72	* SIN3B_21632747_ChIP-Seq_MESCs_Mouse	1.18959340
73	TTF2_22483619_ChIP-Seq_HELA_Human	1.18498988
74	REST_18959480_ChIP-ChIP_MESCs_Mouse	1.17734133
75	NMYC_18555785_Chip-Seq_ESCs_Mouse	1.17432469
76	SMAD3_21741376_ChIP-Seq_EPCs_Human	1.16830931
77	NR4A2_19515692_ChIP-ChIP_MN9D_Mouse	1.16821929
78	CEBPD_23245923_ChIP-Seq_MEFs_Mouse	1.16185357
79	EZH2_27294783_Chip-Seq_NPCs_Mouse	1.15378148
80	E2F4_17652178_ChIP-ChIP_JURKAT_Human	1.14383177
81	ELF1_17652178_ChIP-ChIP_JURKAT_Human	1.14315712
82	POU5F1_18358816_ChIP-ChIP_MESCs_Mouse	1.12717578
83	OCT4_18555785_Chip-Seq_ESCs_Mouse	1.12083699
84	RBPJ_22232070_ChIP-Seq_NCS_Mouse	1.11625156
85	EZH2_27304074_Chip-Seq_ESCs_Mouse	1.11215626
86	SALL1_21062744_ChIP-ChIP_HESCs_Human	1.10748922
87	MYC_18555785_ChIP-Seq_MESCs_Mouse	1.10411070
88	BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse	1.10353426
89	KLF4_18555785_Chip-Seq_ESCs_Mouse	1.10129108
90	TP63_19390658_ChIP-ChIP_HaCaT_Human	1.09047572
91	FOXP3_21729870_ChIP-Seq_TREG_Human	1.07645941
92	PHC1_16625203_ChIP-ChIP_MESCs_Mouse	1.07430431
93	SMAD1_18555785_Chip-Seq_ESCs_Mouse	1.06960326
94	SUZ12_18692474_ChIP-Seq_MESCs_Mouse	1.06546233
95	ZFX_18555785_Chip-Seq_ESCs_Mouse	1.06214812
96	TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse	1.05554652
97	POU5F1_26923725_Chip-Seq_MESODERM_Mouse	1.05554652
98	SUZ12_16625203_ChIP-ChIP_MESCs_Mouse	1.04259385
99	PIAS1_25552417_ChIP-Seq_VCAP_Human	1.04244953
100	REST_21632747_ChIP-Seq_MESCs_Mouse	1.03825687
101	CTCF_18555785_Chip-Seq_ESCs_Mouse	1.03811819
102	IRF4_20064451_ChIP-Seq_CD4+T_Mouse	1.03599567
103	KDM2B_26808549_Chip-Seq_REH_Human	1.03595063
104	CREB1_15753290_ChIP-ChIP_HEK293T_Human	1.03503137
105	ZFP322A_24550733_ChIP-Seq_MESCs_Mouse	1.03263114
106	SMAD4_21799915_ChIP-Seq_A2780_Human	1.03104046
107	ZFP42_18358816_ChIP-ChIP_MESCs_Mouse	1.02611252
108	VDR_23849224_ChIP-Seq_CD4+_Human	1.01957544
109	AR_25329375_ChIP-Seq_VCAP_Human	1.01533474
110	ETV2_25802403_ChIP-Seq_MESCs_Mouse	1.00091438
111	BCAT_22108803_ChIP-Seq_LS180_Human	0.99935482
112	THAP11_20581084_ChIP-Seq_MESCs_Mouse	0.99238604
113	KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse	0.99045643
114	RNF2_16625203_ChIP-ChIP_MESCs_Mouse	0.98810798
115	NCOR_22424771_ChIP-Seq_293T_Human	0.98509917
116	* GABP_19822575_ChIP-Seq_HepG2_Human	0.98433202
117	PU1_27457419_Chip-Seq_LIVER_Mouse	0.98131050
118	ZNF274_21170338_ChIP-Seq_K562_Hela	0.97898509
119	PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human	0.97887149
120	TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse	0.96967353
121	* EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human	0.96771672
122	ESRRB_18555785_Chip-Seq_ESCs_Mouse	0.96668325
123	EZH2_27294783_Chip-Seq_ESCs_Mouse	0.96463471
124	MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human	0.96295907
125	MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse	0.96180322
126	JUN_21703547_ChIP-Seq_K562_Human	0.96090334
127	CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse	0.94820241
128	POU5F1_16153702_ChIP-ChIP_HESCs_Human	0.93478585
129	CRX_20693478_ChIP-Seq_RETINA_Mouse	0.93424374
130	XRN2_22483619_ChIP-Seq_HELA_Human	0.93243682
131	YY1_21170310_ChIP-Seq_MESCs_Mouse	0.92708299
132	JARID2_20064375_ChIP-Seq_MESCs_Mouse	0.92595929
133	FOXA1_27270436_Chip-Seq_PROSTATE_Human	0.92367280
134	FOXA1_25329375_ChIP-Seq_VCAP_Human	0.92367280
135	JARID2_20075857_ChIP-Seq_MESCs_Mouse	0.91492971
136	SOX2_19829295_ChIP-Seq_ESCs_Human	0.91376976
137	NANOG_19829295_ChIP-Seq_ESCs_Human	0.91376976
138	NANOG_16153702_ChIP-ChIP_HESCs_Human	0.90509980
139	SMAD2/3_21741376_ChIP-Seq_EPCs_Human	0.90163708
140	CBP_20019798_ChIP-Seq_JUKART_Human	0.89977127

Predicted mouse phenotypes (MGI)

Rank	Gene Set	Z-score
1	MP0003880_abnormal_central_pattern	4.06445045
2	MP0005410_abnormal_fertilization	3.93143130
3	MP0009379_abnormal_foot_pigmentation	3.08064761
4	MP0001188_hyperpigmentation	2.83365050
5	MP0001529_abnormal_vocalization	2.82061116
6	MP0001986_abnormal_taste_sensitivity	2.76569762
7	MP0001905_abnormal_dopamine_level	2.56387543
8	MP0006276_abnormal_autonomic_nervous	2.39878733
9	MP0009046_muscle_twitch	2.34267951
10	MP0005409_darkened_coat_color	2.33305519
11	MP0008789_abnormal_olfactory_epithelium	2.32791767
12	MP0002736_abnormal_nociception_after	2.29135709
13	MP0001968_abnormal_touch/_nociception	2.28108713
14	MP0003136_yellow_coat_color	2.24761367
15	MP0005171_absent_coat_pigmentation	2.17215622
16	MP0004133_heterotaxia	2.07398421
17	MP0010030_abnormal_orbit_morphology	2.04099148
18	MP0005499_abnormal_olfactory_system	2.00025561
19	MP0005394_taste/olfaction_phenotype	2.00025561
20	MP0002735_abnormal_chemical_nociception	1.91920629
21	MP0002638_abnormal_pupillary_reflex	1.89096514
22	MP0009745_abnormal_behavioral_response	1.87923467
23	MP0004270_analgesia	1.85390151
24	MP0001293_anophthalmia	1.84523714
25	MP0005423_abnormal_somatic_nervous	1.84329657
26	MP0006292_abnormal_olfactory_placode	1.83896318
27	MP0002272_abnormal_nervous_system	1.80762645
28	MP0010386_abnormal_urinary_bladder	1.80758099
29	MP0003121_genomic_imprinting	1.79382662
30	MP0003787_abnormal_imprinting	1.78252167
31	MP0001984_abnormal_olfaction	1.76141161
32	MP0008877_abnormal_DNA_methylation	1.74454472
33	MP0002734_abnormal_mechanical_nocicepti	1.73724588
34	MP0004142_abnormal_muscle_tone	1.72046962
35	MP0000015_abnormal_ear_pigmentation	1.71868384
36	MP0002163_abnormal_gland_morphology	1.67622934
37	MP0002572_abnormal_emotion/affect_behav	1.64768030
38	MP0002064_seizures	1.64033145
39	MP0003698_abnormal_male_reproductive	1.62483687
40	MP0005645_abnormal_hypothalamus_physiol	1.58663725
41	MP0005379_endocrine/exocrine_gland_phen	1.57267751
42	MP0002234_abnormal_pharynx_morphology	1.54334977
43	MP0005174_abnormal_tail_pigmentation	1.53331583
44	MP0003011_delayed_dark_adaptation	1.52869267
45	MP0009697_abnormal_copulation	1.51978076
46	MP0002822_catalepsy	1.50417994
47	MP0000049_abnormal_middle_ear	1.47996615
48	MP0003635_abnormal_synaptic_transmissio	1.45041444
49	MP0002148_abnormal_hypersensitivity_rea	1.42080209
50	MP0000372_irregular_coat_pigmentation	1.40551170
51	MP0001486_abnormal_startle_reflex	1.39751320
52	MP0001440_abnormal_grooming_behavior	1.38104066
53	MP0003890_abnormal_embryonic-extraembry	1.35236872
54	MP0003938_abnormal_ear_development	1.33823917
55	MP0001929_abnormal_gametogenesis	1.33408736
56	MP0000569_abnormal_digit_pigmentation	1.33288487
57	MP0004742_abnormal_vestibular_system	1.31807159
58	MP0003122_maternal_imprinting	1.31158111
59	MP0005084_abnormal_gallbladder_morpholo	1.30392339
60	MP0004885_abnormal_endolymph	1.30097182
61	MP0002938_white_spotting	1.29920688
62	MP0002277_abnormal_respiratory_mucosa	1.28872691
63	MP0003283_abnormal_digestive_organ	1.28658667
64	MP0002837_dystrophic_cardiac_calcinosis	1.27884480
65	MP0001970_abnormal_pain_threshold	1.27749732
66	MP0003878_abnormal_ear_physiology	1.26631537
67	MP0005377_hearing/vestibular/ear_phenot	1.26631537
68	MP0002067_abnormal_sensory_capabilities	1.24881245
69	MP0002102_abnormal_ear_morphology	1.23107657
70	MP0000920_abnormal_myelination	1.21782410
71	MP0002063_abnormal_learning/memory/cond	1.21104779
72	MP0000566_synostosis	1.20741675
73	MP0000778_abnormal_nervous_system	1.19149697
74	MP0002233_abnormal_nose_morphology	1.17515400
75	MP0008995_early_reproductive_senescence	1.16214053
76	MP0006072_abnormal_retinal_apoptosis	1.16013377
77	MP0001501_abnormal_sleep_pattern	1.15933335
78	MP0005551_abnormal_eye_electrophysiolog	1.14161949
79	MP0000955_abnormal_spinal_cord	1.12421956
80	MP0005646_abnormal_pituitary_gland	1.12262889
81	MP0005195_abnormal_posterior_eye	1.10509667
82	MP0002876_abnormal_thyroid_physiology	1.09668055
83	MP0001286_abnormal_eye_development	1.06140281
84	MP0005623_abnormal_meninges_morphology	1.05858798
85	MP0003937_abnormal_limbs/digits/tail_de	1.05839952
86	MP0008057_abnormal_DNA_replication	1.05541800
87	MP0003119_abnormal_digestive_system	1.01015361
88	MP0002095_abnormal_skin_pigmentation	1.00518779
89	MP0003123_paternal_imprinting	1.00299720
90	MP0005248_abnormal_Harderian_gland	0.99880534
91	MP0002928_abnormal_bile_duct	0.99608484
92	MP0005391_vision/eye_phenotype	0.99109052
93	MP0004145_abnormal_muscle_electrophysio	0.98166887
94	MP0001963_abnormal_hearing_physiology	0.97904792
95	MP0002282_abnormal_trachea_morphology	0.97050807
96	MP0002210_abnormal_sex_determination	0.96802508
97	MP0002733_abnormal_thermal_nociception	0.95005559
98	MP0003861_abnormal_nervous_system	0.94756155
99	MP0002184_abnormal_innervation	0.94585887
100	MP0000631_abnormal_neuroendocrine_gland	0.93866322
101	MP0008058_abnormal_DNA_repair	0.93397593
102	MP0005187_abnormal_penis_morphology	0.93262008
103	MP0003186_abnormal_redox_activity	0.93249356
104	MP0003724_increased_susceptibility_to	0.92520144
105	MP0001346_abnormal_lacrimal_gland	0.92131901
106	MP0002557_abnormal_social/conspecific_i	0.91772470
107	MP0003183_abnormal_peptide_metabolism	0.91655027
108	MP0001835_abnormal_antigen_presentation	0.91450798
109	MP0008875_abnormal_xenobiotic_pharmacok	0.91294225
110	MP0000026_abnormal_inner_ear	0.90750318
111	MP0005253_abnormal_eye_physiology	0.90550535
112	MP0002152_abnormal_brain_morphology	0.90276330
113	MP0002751_abnormal_autonomic_nervous	0.88636890
114	MP0001324_abnormal_eye_pigmentation	0.86307005
115	MP0003950_abnormal_plasma_membrane	0.85559695
116	MP0001485_abnormal_pinna_reflex	0.85355718
117	MP0003755_abnormal_palate_morphology	0.84611807
118	MP0005386_behavior/neurological_phenoty	0.83009888
119	MP0004924_abnormal_behavior	0.83009888
120	MP0000647_abnormal_sebaceous_gland	0.81990180
121	MP0008004_abnormal_stomach_pH	0.81462750
122	MP0001727_abnormal_embryo_implantation	0.79632278
123	MP0000681_abnormal_thyroid_gland	0.79332831
124	MP0004043_abnormal_pH_regulation	0.79146252
125	MP0009785_altered_susceptibility_to	0.79028370
126	MP0005408_hypopigmentation	0.78940058
127	MP0002229_neurodegeneration	0.78571132
128	MP0001145_abnormal_male_reproductive	0.78121444
129	MP0002752_abnormal_somatic_nervous	0.77724539
130	MP0004859_abnormal_synaptic_plasticity	0.76744753
131	MP0002882_abnormal_neuron_morphology	0.76323320
132	MP0004134_abnormal_chest_morphology	0.73398079
133	MP0006035_abnormal_mitochondrial_morpho	0.73264581
134	MP0002653_abnormal_ependyma_morphology	0.72856084
135	MP0002160_abnormal_reproductive_system	0.72752102
136	MP0002066_abnormal_motor_capabilities/c	0.71172718
137	MP0002161_abnormal_fertility/fecundity	0.70623269
138	MP0003786_premature_aging	0.70102410
139	MP0002009_preneoplasia	0.69807369
140	MP0005075_abnormal_melanosome_morpholog	0.69418280

Predicted human phenotypes

Rank	Gene Set	Z-score
1	Respiratory insufficiency due to defective ciliary clearance (HP:0200073)	7.23600977
2	Absent/shortened dynein arms (HP:0200106)	6.01757981
3	Dynein arm defect of respiratory motile cilia (HP:0012255)	6.01757981
4	Abnormal respiratory motile cilium physiology (HP:0012261)	5.91492667
5	Abnormal ciliary motility (HP:0012262)	5.86652655
6	Abnormal respiratory epithelium morphology (HP:0012253)	5.23129664
7	Abnormal respiratory motile cilium morphology (HP:0005938)	5.23129664
8	Acute necrotizing encephalopathy (HP:0006965)	4.89483429
9	Rhinitis (HP:0012384)	4.63346557
10	Abnormal mitochondria in muscle tissue (HP:0008316)	4.25235846
11	Mitochondrial inheritance (HP:0001427)	4.18050357
12	Progressive macrocephaly (HP:0004481)	4.16642496
13	Medial flaring of the eyebrow (HP:0010747)	3.86755152
14	Acute encephalopathy (HP:0006846)	3.57569145
15	Increased hepatocellular lipid droplets (HP:0006565)	3.54271011
16	Pancreatic fibrosis (HP:0100732)	3.51874681
17	Increased CSF lactate (HP:0002490)	3.40461067
18	Hepatocellular necrosis (HP:0001404)	3.32956650
19	Chronic bronchitis (HP:0004469)	3.28226072
20	True hermaphroditism (HP:0010459)	3.25125056
21	Renal Fanconi syndrome (HP:0001994)	3.22115834
22	Gait imbalance (HP:0002141)	3.17224976
23	Hypothermia (HP:0002045)	3.09898018
24	Congenital primary aphakia (HP:0007707)	3.07252907
25	Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)	3.05507286
26	Molar tooth sign on MRI (HP:0002419)	2.99308929
27	Abnormality of midbrain morphology (HP:0002418)	2.99308929
28	Nephrogenic diabetes insipidus (HP:0009806)	2.94975931
29	Septo-optic dysplasia (HP:0100842)	2.94617139
30	Optic disc pallor (HP:0000543)	2.90278046
31	Congenital nonbullous ichthyosiform erythroderma (HP:0007479)	2.89790320
32	Lipid accumulation in hepatocytes (HP:0006561)	2.89230266
33	3-Methylglutaconic aciduria (HP:0003535)	2.85561218
34	Muscle abnormality related to mitochondrial dysfunction (HP:0003800)	2.82852873
35	Nephronophthisis (HP:0000090)	2.77697218
36	Abnormality of renal resorption (HP:0011038)	2.77554019
37	Cystic liver disease (HP:0006706)	2.73763253
38	Abnormal hair whorl (HP:0010721)	2.73420717
39	Abnormality of the labia minora (HP:0012880)	2.67248865
40	Genital tract atresia (HP:0001827)	2.67117453
41	Bronchiectasis (HP:0002110)	2.60174699
42	Pancreatic cysts (HP:0001737)	2.59660811
43	Vaginal atresia (HP:0000148)	2.58636264
44	Exertional dyspnea (HP:0002875)	2.57180659
45	Hepatic necrosis (HP:0002605)	2.55982585
46	Exercise intolerance (HP:0003546)	2.54776314
47	Leukodystrophy (HP:0002415)	2.45646989
48	Abnormal activity of mitochondrial respiratory chain (HP:0011922)	2.44260986
49	Decreased activity of mitochondrial respiratory chain (HP:0008972)	2.44260986
50	Increased intramyocellular lipid droplets (HP:0012240)	2.25983277
51	Focal motor seizures (HP:0011153)	2.24004911
52	Parakeratosis (HP:0001036)	2.22929929
53	Median cleft lip (HP:0000161)	2.22458500
54	Respiratory failure (HP:0002878)	2.21563807
55	Anophthalmia (HP:0000528)	2.21523962
56	Colon cancer (HP:0003003)	2.19908286
57	Macrocytic anemia (HP:0001972)	2.19643263
58	Type II lissencephaly (HP:0007260)	2.19001262
59	Abnormality of cells of the erythroid lineage (HP:0012130)	2.18724067
60	Tubulointerstitial nephritis (HP:0001970)	2.17889829
61	Poor coordination (HP:0002370)	2.13669287
62	Rib fusion (HP:0000902)	2.12625567
63	Abnormality of glycolysis (HP:0004366)	2.12057622
64	Increased serum pyruvate (HP:0003542)	2.12057622
65	Optic nerve hypoplasia (HP:0000609)	2.11487104
66	Retinal dysplasia (HP:0007973)	2.08975031
67	Abnormality of the renal medulla (HP:0100957)	2.06715630
68	Lissencephaly (HP:0001339)	2.05894968
69	Aplasia/Hypoplasia of the lens (HP:0008063)	2.05864907
70	Polyphagia (HP:0002591)	2.05220598
71	Postaxial foot polydactyly (HP:0001830)	2.04087376
72	Congenital, generalized hypertrichosis (HP:0004540)	2.03739537
73	Preaxial hand polydactyly (HP:0001177)	2.03729542
74	Absent septum pellucidum (HP:0001331)	2.00533830
75	Sclerocornea (HP:0000647)	1.96692253
76	Infertility (HP:0000789)	1.96117135
77	Aplasia/Hypoplasia of the tongue (HP:0010295)	1.95120337
78	Type I transferrin isoform profile (HP:0003642)	1.94511292
79	Chronic sinusitis (HP:0011109)	1.94313545
80	Lactic acidosis (HP:0003128)	1.93582722
81	Oligodactyly (hands) (HP:0001180)	1.92823277
82	Aplasia/Hypoplasia of the optic nerve (HP:0008058)	1.92697535
83	Hyperglycinemia (HP:0002154)	1.92573630
84	Cerebral edema (HP:0002181)	1.92445693
85	Myokymia (HP:0002411)	1.91603881
86	Abnormal number of erythroid precursors (HP:0012131)	1.91104283
87	Respiratory difficulties (HP:0002880)	1.90538557
88	Narrow forehead (HP:0000341)	1.89296687
89	Limb dystonia (HP:0002451)	1.87931355
90	Bronchitis (HP:0012387)	1.85464780
91	Degeneration of the lateral corticospinal tracts (HP:0002314)	1.85198407
92	Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)	1.85198407
93	Male pseudohermaphroditism (HP:0000037)	1.84568729
94	Reticulocytopenia (HP:0001896)	1.84259162
95	Tubular atrophy (HP:0000092)	1.81125540
96	Increased serum lactate (HP:0002151)	1.80149366
97	Postaxial hand polydactyly (HP:0001162)	1.80054035
98	Pendular nystagmus (HP:0012043)	1.78499847
99	Specific learning disability (HP:0001328)	1.77722597
100	Abnormal biliary tract physiology (HP:0012439)	1.75479632
101	Bile duct proliferation (HP:0001408)	1.75479632
102	Epileptic encephalopathy (HP:0200134)	1.74796628
103	Concave nail (HP:0001598)	1.74708170
104	Aplasia/Hypoplasia of the tibia (HP:0005772)	1.74236895
105	Severe visual impairment (HP:0001141)	1.73657836
106	X-linked dominant inheritance (HP:0001423)	1.69306331
107	Abnormality of the renal cortex (HP:0011035)	1.68805647
108	Congenital ichthyosiform erythroderma (HP:0007431)	1.68714109
109	Poor suck (HP:0002033)	1.68544067
110	Recurrent sinusitis (HP:0011108)	1.67077116
111	Holoprosencephaly (HP:0001360)	1.65833258
112	Maternal diabetes (HP:0009800)	1.65289838
113	Anencephaly (HP:0002323)	1.65057662
114	Nasal polyposis (HP:0100582)	1.64915421
115	Furrowed tongue (HP:0000221)	1.64554782
116	Dandy-Walker malformation (HP:0001305)	1.64268725
117	Aplasia/Hypoplasia of the spleen (HP:0010451)	1.63640839
118	Abnormal drinking behavior (HP:0030082)	1.63418054
119	Chronic hepatic failure (HP:0100626)	1.63180910
120	Decreased central vision (HP:0007663)	1.62758952
121	Congenital hepatic fibrosis (HP:0002612)	1.62097180
122	Esotropia (HP:0000565)	1.61181780
123	Increased muscle lipid content (HP:0009058)	1.60645315
124	Bifid tongue (HP:0010297)	1.60411398
125	Short tibia (HP:0005736)	1.57134501
126	Occipital encephalocele (HP:0002085)	1.56018217
127	Supernumerary spleens (HP:0009799)	1.52151741
128	Metaphyseal dysplasia (HP:0100255)	1.51680282
129	Oculomotor apraxia (HP:0000657)	1.49393368
130	Aganglionic megacolon (HP:0002251)	1.47848808
131	Pallor (HP:0000980)	1.47623535

Predicted kinase interactions (KEA)

Rank	Gene Set	Z-score
1	CASK	3.46733408
2	STK16	3.19875408
3	MAP3K12	3.11920835
4	VRK2	2.71106013
5	MST4	2.34879978
6	STK39	2.29848689
7	GRK7	2.18787318
8	CDC7	2.16362983
9	MAP2K7	2.15092621
10	MAP4K2	2.09036647
11	VRK1	2.04696247
12	BMPR1B	2.00546195
13	BMPR2	1.96967380
14	TRIM28	1.84935366
15	TNIK	1.78502420
16	OXSR1	1.76968370
17	GRK5	1.75314281
18	PLK2	1.70792592
19	MUSK	1.68835838
20	MAPKAPK5	1.68555867
21	MYLK	1.65027535
22	PINK1	1.63615116
23	EPHB2	1.61701135
24	ADRBK2	1.60398327
25	PBK	1.58951014
26	NUAK1	1.58565272
27	BCKDK	1.56787808
28	PDK3	1.49868019
29	PDK4	1.49868019
30	FRK	1.48556980
31	NME1	1.44196005
32	ARAF	1.42904364
33	RIPK4	1.42105910
34	LIMK1	1.41392441
35	BCR	1.38740514
36	CDK19	1.36772688
37	ERBB3	1.36095469
38	IRAK4	1.35958092
39	PIM2	1.35498645
40	CSNK1G2	1.35065275
41	PNCK	1.33862472
42	MAPK13	1.32986371
43	WNK4	1.32354440
44	MKNK1	1.31703464
45	MAPK15	1.28570256
46	NTRK2	1.25442026
47	EIF2AK3	1.20834523
48	BUB1	1.17993948
49	NME2	1.13299219
50	PAK3	1.09811619
51	PTK2B	1.09477665
52	TESK1	1.09365264
53	INSRR	1.09294430
54	DYRK2	1.09144347
55	SIK3	1.07505770
56	YES1	1.07355209
57	CCNB1	1.05670983
58	CAMK2B	1.02450659
59	CSNK1G1	1.02344316
60	UHMK1	1.01319622
61	PDK2	1.00704088
62	MKNK2	0.99820315
63	EPHA4	0.98621215
64	NEK6	0.96660715
65	PLK1	0.95945847
66	PLK4	0.95054447
67	CDK8	0.91807505
68	BRAF	0.89844333
69	SRPK1	0.88356785
70	PASK	0.87139620
71	CAMK2A	0.86981791
72	PKN1	0.79057476
73	TEC	0.78813982
74	PRKCE	0.77702502
75	CAMK2D	0.74985710
76	CSNK1A1L	0.74647716
77	ADRBK1	0.71741690
78	TSSK6	0.70673855
79	TGFBR1	0.69123707
80	AKT3	0.68681942
81	TAF1	0.67209601
82	CDK3	0.67148274
83	MAP2K4	0.66561225
84	ATR	0.65491924
85	WEE1	0.65097526
86	ACVR1B	0.64865725
87	AURKA	0.63445665
88	NEK1	0.63246101
89	MARK1	0.61144712
90	FES	0.60898480
91	FGFR2	0.60558394
92	FGR	0.58592808
93	KIT	0.58434561
94	CSNK1G3	0.58108814
95	EIF2AK2	0.57365146
96	IRAK1	0.57164390
97	NTRK3	0.56425022
98	IRAK2	0.55838614
99	AURKB	0.55663751
100	RPS6KA5	0.54777237
101	SYK	0.54751665
102	DYRK1A	0.54531186
103	ZAK	0.53645413
104	NEK2	0.53514729
105	TTK	0.52728865
106	CHEK2	0.51093901
107	CSNK1A1	0.50942627
108	BRSK1	0.50824809
109	STK38L	0.50116021
110	PHKG2	0.49934996
111	PHKG1	0.49934996
112	CAMK2G	0.49418510
113	DYRK1B	0.48882245
114	DAPK1	0.47661471
115	STK11	0.47649709
116	CLK1	0.47451180
117	CSNK1E	0.47353147
118	PRKG1	0.46978357
119	TLK1	0.46895558
120	WNK3	0.45436270
121	BRSK2	0.43768930
122	TIE1	0.43263488
123	CSNK2A1	0.43161878
124	PRKCG	0.42991899
125	PRKACA	0.42939962
126	MOS	0.42907809
127	DYRK3	0.42227965
128	MINK1	0.42066313
129	CDK18	0.42050253
130	MAP3K4	0.41919784
131	PLK3	0.41915161
132	ABL2	0.41458800
133	TRPM7	0.39714162
134	CDK14	0.39366083
135	OBSCN	0.39104361
136	CDK5	0.38224035
137	GRK1	0.38029454
138	CAMK1	0.37919692
139	PRKACB	0.36281393
140	PRKCD	0.36126971
141	CDK15	0.35598144
142	CDK11A	0.35146184
143	CSNK2A2	0.34394264

Predicted pathways (KEGG)

Rank	Gene Set	Z-score
1	Oxidative phosphorylation_Homo sapiens_hsa00190	5.02941502
2	Parkinsons disease_Homo sapiens_hsa05012	4.09770954
3	Huntingtons disease_Homo sapiens_hsa05016	3.41977234
4	Protein export_Homo sapiens_hsa03060	3.41624928
5	Ribosome_Homo sapiens_hsa03010	3.41385556
6	Alzheimers disease_Homo sapiens_hsa05010	3.29012756
7	Proteasome_Homo sapiens_hsa03050	3.03201492
8	RNA polymerase_Homo sapiens_hsa03020	2.38973149
9	Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932	2.37334943
10	Collecting duct acid secretion_Homo sapiens_hsa04966	2.30268820
11	Cardiac muscle contraction_Homo sapiens_hsa04260	1.86988852
12	Basal transcription factors_Homo sapiens_hsa03022	1.66028463
13	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563	1.60211528
14	Nicotine addiction_Homo sapiens_hsa05033	1.59337847
15	Vibrio cholerae infection_Homo sapiens_hsa05110	1.55112905
16	SNARE interactions in vesicular transport_Homo sapiens_hsa04130	1.54404353
17	Rheumatoid arthritis_Homo sapiens_hsa05323	1.52109736
18	Taurine and hypotaurine metabolism_Homo sapiens_hsa00430	1.47409591
19	Butanoate metabolism_Homo sapiens_hsa00650	1.45532809
20	Phototransduction_Homo sapiens_hsa04744	1.42621010
21	Serotonergic synapse_Homo sapiens_hsa04726	1.40762665
22	Pyrimidine metabolism_Homo sapiens_hsa00240	1.30612315
23	Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080	1.26955871
24	Terpenoid backbone biosynthesis_Homo sapiens_hsa00900	1.26053968
25	Retrograde endocannabinoid signaling_Homo sapiens_hsa04723	1.23011432
26	Phagosome_Homo sapiens_hsa04145	1.22101490
27	Synaptic vesicle cycle_Homo sapiens_hsa04721	1.21273770
28	Taste transduction_Homo sapiens_hsa04742	1.20482256
29	Ether lipid metabolism_Homo sapiens_hsa00565	1.19630303
30	Folate biosynthesis_Homo sapiens_hsa00790	1.18922691
31	Purine metabolism_Homo sapiens_hsa00230	1.18868369
32	Homologous recombination_Homo sapiens_hsa03440	1.17773650
33	Basal cell carcinoma_Homo sapiens_hsa05217	1.16869470
34	Propanoate metabolism_Homo sapiens_hsa00640	1.10897748
35	Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623	1.10158480
36	Maturity onset diabetes of the young_Homo sapiens_hsa04950	1.09806278
37	Morphine addiction_Homo sapiens_hsa05032	1.06454240
38	Nucleotide excision repair_Homo sapiens_hsa03420	1.04553694
39	Hedgehog signaling pathway_Homo sapiens_hsa04340	1.04194226
40	Spliceosome_Homo sapiens_hsa03040	1.01300881
41	Non-homologous end-joining_Homo sapiens_hsa03450	1.00344201
42	Nitrogen metabolism_Homo sapiens_hsa00910	0.99978616
43	Arachidonic acid metabolism_Homo sapiens_hsa00590	0.99574909
44	Sulfur metabolism_Homo sapiens_hsa00920	0.98961172
45	Peroxisome_Homo sapiens_hsa04146	0.98865315
46	Fatty acid elongation_Homo sapiens_hsa00062	0.98339277
47	Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280	0.97636426
48	Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120	0.96904535
49	Glycine, serine and threonine metabolism_Homo sapiens_hsa00260	0.91937360
50	Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980	0.91291879
51	Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601	0.90284299
52	Glutamatergic synapse_Homo sapiens_hsa04724	0.90144463
53	Tryptophan metabolism_Homo sapiens_hsa00380	0.89589155
54	Circadian entrainment_Homo sapiens_hsa04713	0.88590416
55	Chemical carcinogenesis_Homo sapiens_hsa05204	0.87785521
56	GABAergic synapse_Homo sapiens_hsa04727	0.87580702
57	Allograft rejection_Homo sapiens_hsa05330	0.86510983
58	Drug metabolism - cytochrome P450_Homo sapiens_hsa00982	0.86112021
59	Fanconi anemia pathway_Homo sapiens_hsa03460	0.84709749
60	Long-term depression_Homo sapiens_hsa04730	0.83408326
61	Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630	0.83157858
62	Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512	0.82533802
63	Olfactory transduction_Homo sapiens_hsa04740	0.82328157
64	Amphetamine addiction_Homo sapiens_hsa05031	0.81646110
65	Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072	0.79669805
66	Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962	0.78957345
67	Caffeine metabolism_Homo sapiens_hsa00232	0.77466158
68	DNA replication_Homo sapiens_hsa03030	0.75890392
69	Dopaminergic synapse_Homo sapiens_hsa04728	0.74725076
70	Asthma_Homo sapiens_hsa05310	0.73067766
71	RNA degradation_Homo sapiens_hsa03018	0.72014226
72	Graft-versus-host disease_Homo sapiens_hsa05332	0.70563107
73	Autoimmune thyroid disease_Homo sapiens_hsa05320	0.70253798
74	Mismatch repair_Homo sapiens_hsa03430	0.70141214
75	Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603	0.69143302
76	Linoleic acid metabolism_Homo sapiens_hsa00591	0.69016273
77	Ascorbate and aldarate metabolism_Homo sapiens_hsa00053	0.68999722
78	African trypanosomiasis_Homo sapiens_hsa05143	0.67888510
79	beta-Alanine metabolism_Homo sapiens_hsa00410	0.66479027
80	Sulfur relay system_Homo sapiens_hsa04122	0.65932785
81	Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008	0.64672686
82	Long-term potentiation_Homo sapiens_hsa04720	0.63896467
83	Sphingolipid metabolism_Homo sapiens_hsa00600	0.63402443
84	Type I diabetes mellitus_Homo sapiens_hsa04940	0.59640857
85	Renin secretion_Homo sapiens_hsa04924	0.59375973
86	Base excision repair_Homo sapiens_hsa03410	0.58409873
87	Primary bile acid biosynthesis_Homo sapiens_hsa00120	0.58051809
88	Tyrosine metabolism_Homo sapiens_hsa00350	0.56760678
89	Selenocompound metabolism_Homo sapiens_hsa00450	0.55379585
90	Pathogenic Escherichia coli infection_Homo sapiens_hsa05130	0.53701641
91	Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604	0.53625576
92	Retinol metabolism_Homo sapiens_hsa00830	0.53062669
93	Cysteine and methionine metabolism_Homo sapiens_hsa00270	0.52732751
94	Alcoholism_Homo sapiens_hsa05034	0.52225536
95	One carbon pool by folate_Homo sapiens_hsa00670	0.52221132
96	Metabolic pathways_Homo sapiens_hsa01100	0.51581609
97	Hippo signaling pathway_Homo sapiens_hsa04390	0.50153888
98	Cocaine addiction_Homo sapiens_hsa05030	0.49039980
99	Calcium signaling pathway_Homo sapiens_hsa04020	0.48535469
100	Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040	0.46811027
101	Steroid hormone biosynthesis_Homo sapiens_hsa00140	0.45866840
102	Ubiquitin mediated proteolysis_Homo sapiens_hsa04120	0.45679694
103	alpha-Linolenic acid metabolism_Homo sapiens_hsa00592	0.43863536
104	Cholinergic synapse_Homo sapiens_hsa04725	0.42689444
105	Fatty acid degradation_Homo sapiens_hsa00071	0.40686334
106	Salivary secretion_Homo sapiens_hsa04970	0.40498523
107	Salmonella infection_Homo sapiens_hsa05132	0.40073121
108	Pertussis_Homo sapiens_hsa05133	0.39768456
109	Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014	0.37743266
110	Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550	0.37237432
111	Epstein-Barr virus infection_Homo sapiens_hsa05169	0.36772623
112	Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130	0.36532397
113	Pentose and glucuronate interconversions_Homo sapiens_hsa00040	0.36310040
114	Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514	0.34345345
115	Regulation of autophagy_Homo sapiens_hsa04140	0.33867882
116	Insulin secretion_Homo sapiens_hsa04911	0.33721046
117	RNA transport_Homo sapiens_hsa03013	0.33299627
118	Steroid biosynthesis_Homo sapiens_hsa00100	0.32032817
119	Wnt signaling pathway_Homo sapiens_hsa04310	0.29854145
120	Fatty acid metabolism_Homo sapiens_hsa01212	0.29677182
121	Gastric acid secretion_Homo sapiens_hsa04971	0.29501857
122	Phenylalanine metabolism_Homo sapiens_hsa00360	0.29423630
123	Mineral absorption_Homo sapiens_hsa04978	0.28678472
124	Cell cycle_Homo sapiens_hsa04110	0.28365245
125	Renin-angiotensin system_Homo sapiens_hsa04614	0.27909543
126	Hematopoietic cell lineage_Homo sapiens_hsa04640	0.27455801
127	Malaria_Homo sapiens_hsa05144	0.27326679
128	Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750	0.26604290
129	Glutathione metabolism_Homo sapiens_hsa00480	0.24719507
130	NOD-like receptor signaling pathway_Homo sapiens_hsa04621	0.24131687
131	Pyruvate metabolism_Homo sapiens_hsa00620	0.23967064
132	Oocyte meiosis_Homo sapiens_hsa04114	0.23915905
133	Vascular smooth muscle contraction_Homo sapiens_hsa04270	0.23477364
134	Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860	0.22946985
135	Axon guidance_Homo sapiens_hsa04360	0.22383932
136	Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060	0.22234194
137	N-Glycan biosynthesis_Homo sapiens_hsa00510	0.20368522
138	Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321	0.20272627

TCTEX1D2

Functional Annotation Prediction

Predicted biological processes (GO)

Predicted upstream transcription factors (ChEA)

Predicted mouse phenotypes (MGI)

Predicted human phenotypes

Predicted kinase interactions (KEA)

Predicted pathways (KEGG)

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