TCTEX1D4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)9.88945262
2central nervous system myelination (GO:0022010)9.10039927
3axon ensheathment in central nervous system (GO:0032291)9.10039927
4axoneme assembly (GO:0035082)8.98487123
5left/right pattern formation (GO:0060972)8.56719564
6GTP biosynthetic process (GO:0006183)7.78116595
7cilium or flagellum-dependent cell motility (GO:0001539)7.62750770
8epithelial cilium movement (GO:0003351)7.44112786
9regulation of cilium movement (GO:0003352)7.40147605
10tolerance induction (GO:0002507)7.30373147
11UTP biosynthetic process (GO:0006228)6.77342642
12vitamin transmembrane transport (GO:0035461)6.34369965
13nucleoside diphosphate phosphorylation (GO:0006165)6.27818434
14ventricular system development (GO:0021591)6.27627120
15primary alcohol catabolic process (GO:0034310)6.27465562
16UTP metabolic process (GO:0046051)6.21541529
17pyrimidine-containing compound transmembrane transport (GO:0072531)6.09321296
18epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.89322692
19protein localization to cilium (GO:0061512)5.46766983
20ethanol metabolic process (GO:0006067)5.32421281
21response to xenobiotic stimulus (GO:0009410)5.27605706
22left/right axis specification (GO:0070986)5.27107850
23negative regulation of T cell differentiation in thymus (GO:0033085)5.14814409
24positive regulation of tolerance induction (GO:0002645)5.06651993
25negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)5.04374367
26regulation of germinal center formation (GO:0002634)4.87679062
27negative regulation of immunoglobulin mediated immune response (GO:0002890)4.87426948
28negative regulation of B cell mediated immunity (GO:0002713)4.87426948
29CTP metabolic process (GO:0046036)4.80179751
30CTP biosynthetic process (GO:0006241)4.80179751
31lung epithelium development (GO:0060428)4.79075348
32diterpenoid biosynthetic process (GO:0016102)4.71198892
33photoreceptor cell differentiation (GO:0046530)4.56138777
34eye photoreceptor cell differentiation (GO:0001754)4.56138777
35guanosine-containing compound biosynthetic process (GO:1901070)4.55954239
36motile cilium assembly (GO:0044458)4.55673460
37glomerular epithelial cell development (GO:0072310)4.53443225
38myelination (GO:0042552)4.43871253
39ensheathment of neurons (GO:0007272)4.42916723
40axon ensheathment (GO:0008366)4.42916723
41microtubule bundle formation (GO:0001578)4.37566512
42fatty acid elongation (GO:0030497)4.35316704
43regulation of microtubule-based movement (GO:0060632)4.35139841
44pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)4.26141308
45centriole assembly (GO:0098534)4.16821438
46intraciliary transport (GO:0042073)4.08753984
47regulation of pigment cell differentiation (GO:0050932)4.02179017
48sperm capacitation (GO:0048240)4.00098193
49pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.99990557
50establishment of apical/basal cell polarity (GO:0035089)3.94924005
51regulation of interleukin-5 production (GO:0032674)3.93196171
52regulation of tolerance induction (GO:0002643)3.91308556
53long-chain fatty acid biosynthetic process (GO:0042759)3.90057926
54oligodendrocyte differentiation (GO:0048709)3.83794465
55negative regulation of humoral immune response (GO:0002921)3.82361619
56regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.77140207
57establishment of monopolar cell polarity (GO:0061162)3.75957849
58establishment or maintenance of monopolar cell polarity (GO:0061339)3.75957849
59nucleotide phosphorylation (GO:0046939)3.74871727
60import into cell (GO:0098657)3.68275857
61cilium morphogenesis (GO:0060271)3.63301261
62ethanol oxidation (GO:0006069)3.61581053
63cilium organization (GO:0044782)3.61234529
64limb bud formation (GO:0060174)3.60516648
65regulation of interleukin-13 production (GO:0032656)3.55215828
66hydrogen peroxide biosynthetic process (GO:0050665)3.51934618
67cytoplasmic microtubule organization (GO:0031122)3.48181504
68presynaptic membrane assembly (GO:0097105)3.46230899
69otic vesicle formation (GO:0030916)3.43745700
70retinoic acid metabolic process (GO:0042573)3.39427061
71cilium assembly (GO:0042384)3.37187751
72regulation of interleukin-6 biosynthetic process (GO:0045408)3.32389168
73pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.31804842
74exogenous drug catabolic process (GO:0042738)3.30213840
75negative regulation of execution phase of apoptosis (GO:1900118)3.29304440
76presynaptic membrane organization (GO:0097090)3.26292398
77establishment of tissue polarity (GO:0007164)3.23598674
78establishment of planar polarity (GO:0001736)3.23598674
79asymmetric protein localization (GO:0008105)3.23115273
80terpenoid biosynthetic process (GO:0016114)3.21483307
81protein palmitoylation (GO:0018345)3.20163107
82reactive oxygen species biosynthetic process (GO:1903409)3.09775352
83response to methylmercury (GO:0051597)3.05585376
84cellular component assembly involved in morphogenesis (GO:0010927)3.05504129
85phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.04126475
86regulation of macrophage chemotaxis (GO:0010758)3.01649000
87nucleoside diphosphate metabolic process (GO:0009132)3.01505839
88hypotonic response (GO:0006971)2.98768498
89drug catabolic process (GO:0042737)2.96152325
90myelin maintenance (GO:0043217)2.93579354
91positive regulation of meiotic cell cycle (GO:0051446)2.91004020
92regulation of mononuclear cell migration (GO:0071675)2.90457250
93regulation of toll-like receptor 4 signaling pathway (GO:0034143)2.88619032
94negative regulation of protein localization to cell surface (GO:2000009)2.84629485
95negative regulation of neurotransmitter secretion (GO:0046929)2.84173319
96positive regulation of meiosis (GO:0045836)2.84076188
97negative regulation of inclusion body assembly (GO:0090084)2.83476096
98microtubule depolymerization (GO:0007019)2.81224642
99primary alcohol metabolic process (GO:0034308)2.80948185
100pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.78480669
101retinol metabolic process (GO:0042572)2.71011940
102leukocyte migration involved in inflammatory response (GO:0002523)2.70783541
103microtubule-based movement (GO:0007018)2.69104276
104Leydig cell differentiation (GO:0033327)2.66214026
105microtubule polymerization or depolymerization (GO:0031109)2.66083377
106astrocyte development (GO:0014002)2.63153266
107multicellular organismal water homeostasis (GO:0050891)2.62816654
108apical protein localization (GO:0045176)2.62302836
109pyrimidine ribonucleoside biosynthetic process (GO:0046132)2.60757501
110nonribosomal peptide biosynthetic process (GO:0019184)2.60603555
111negative regulation of neurotransmitter transport (GO:0051589)2.59101057
112polyol transport (GO:0015791)2.56416959
113carnitine metabolic process (GO:0009437)2.55750290
114negative regulation of adaptive immune response (GO:0002820)2.54251984
115microtubule severing (GO:0051013)2.53886738
116sperm motility (GO:0030317)2.53346994
117O-glycan processing (GO:0016266)2.53164846
118cell projection assembly (GO:0030031)2.52726329
119regulation of glucose import in response to insulin stimulus (GO:2001273)2.52661523
120positive regulation of protein kinase C signaling (GO:0090037)2.52100492
121superoxide anion generation (GO:0042554)2.50387796
122negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.49137500
123L-amino acid import (GO:0043092)2.45429512
124pyrimidine ribonucleotide biosynthetic process (GO:0009220)2.45159540
125peptidyl-tyrosine autophosphorylation (GO:0038083)2.44479720
126positive regulation of smoothened signaling pathway (GO:0045880)2.44341260
127magnesium ion transport (GO:0015693)2.41824059
128regulation of microtubule depolymerization (GO:0031114)2.41743616
129determination of left/right symmetry (GO:0007368)2.41591259
130glycerophospholipid catabolic process (GO:0046475)2.40424111
131regulation of collateral sprouting (GO:0048670)2.40182552
132excretion (GO:0007588)2.40126469
133neuron remodeling (GO:0016322)2.39985408
134short-term memory (GO:0007614)2.39599836
135membrane assembly (GO:0071709)2.39145226
136smoothened signaling pathway (GO:0007224)2.39091687
137regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.38533564
138water homeostasis (GO:0030104)2.37581951
139retina layer formation (GO:0010842)2.37581081
140embryonic body morphogenesis (GO:0010172)2.37522471
141phosphatidylcholine acyl-chain remodeling (GO:0036151)2.36706700
142positive regulation of cellular response to insulin stimulus (GO:1900078)2.36668844
143regulation of feeding behavior (GO:0060259)2.36608446
144virion attachment to host cell (GO:0019062)2.35448322
145adhesion of symbiont to host cell (GO:0044650)2.35448322
146developmental induction (GO:0031128)2.34407092
147cerebral cortex radially oriented cell migration (GO:0021799)2.34187063
148purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.33827685
149one-carbon compound transport (GO:0019755)2.32691217
150cell-cell signaling involved in cell fate commitment (GO:0045168)2.31357308
151peptide biosynthetic process (GO:0043043)2.31071256
152neuronal action potential propagation (GO:0019227)2.30831246
153gas transport (GO:0015669)2.27345513
154positive regulation of cellular amine metabolic process (GO:0033240)2.27265273
155lateral ventricle development (GO:0021670)2.27205674
156regulation of type B pancreatic cell apoptotic process (GO:2000674)2.26475264
157cholesterol biosynthetic process (GO:0006695)2.26053929
158purine nucleoside triphosphate biosynthetic process (GO:0009145)2.25040913
159centriole replication (GO:0007099)2.24106683
160cellular response to epinephrine stimulus (GO:0071872)2.23694274
161spermatid nucleus differentiation (GO:0007289)2.23688654
162negative regulation of myoblast differentiation (GO:0045662)2.23582936
163glutathione derivative metabolic process (GO:1901685)2.23370481
164glutathione derivative biosynthetic process (GO:1901687)2.23370481
165determination of bilateral symmetry (GO:0009855)2.23174270
166regulation of T cell differentiation in thymus (GO:0033081)2.23171046
167ear development (GO:0043583)2.22230617
168nonmotile primary cilium assembly (GO:0035058)2.22069625
169myoblast migration (GO:0051451)2.21807388
170positive regulation of oligodendrocyte differentiation (GO:0048714)2.20640775
171lateral sprouting from an epithelium (GO:0060601)2.20128432
172hydrogen peroxide catabolic process (GO:0042744)2.19789517
173mitochondrion degradation (GO:0000422)2.18994408
174specification of symmetry (GO:0009799)2.18507048
175negative regulation of lymphocyte mediated immunity (GO:0002707)2.17577684
176oligosaccharide biosynthetic process (GO:0009312)2.16543227
177microtubule-based process (GO:0007017)2.14404753
178progesterone metabolic process (GO:0042448)2.14269374
179cilium movement (GO:0003341)10.3238332

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat6.11253514
2CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.85119502
3FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.93817270
4CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.31203951
5AR_21572438_ChIP-Seq_LNCaP_Human2.21333772
6BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.21113310
7TRIM28_21343339_ChIP-Seq_HEK293_Human2.15554239
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.92111844
9GBX2_23144817_ChIP-Seq_PC3_Human1.88472696
10JARID2_20064375_ChIP-Seq_MESCs_Mouse1.86971375
11TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.86116940
12SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.86074237
13ER_23166858_ChIP-Seq_MCF-7_Human1.85058445
14EZH2_27304074_Chip-Seq_ESCs_Mouse1.83147534
15SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.82557892
16ESR1_20079471_ChIP-ChIP_T-47D_Human1.78779796
17EZH2_27294783_Chip-Seq_ESCs_Mouse1.78280967
18SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.78128827
19CDX2_19796622_ChIP-Seq_MESCs_Mouse1.77945954
20SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.77058309
21PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.76766118
22SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.76601393
23STAT6_21828071_ChIP-Seq_BEAS2B_Human1.75388551
24ESR2_21235772_ChIP-Seq_MCF-7_Human1.75338022
25WT1_19549856_ChIP-ChIP_CCG9911_Human1.71879340
26SUZ12_27294783_Chip-Seq_ESCs_Mouse1.71617940
27BMI1_23680149_ChIP-Seq_NPCS_Mouse1.70139753
28STAT1_20625510_ChIP-Seq_HELA_Human1.69693954
29ELF1_20517297_ChIP-Seq_JURKAT_Human1.68649659
30SMC4_20622854_ChIP-Seq_HELA_Human1.67384611
31EED_16625203_ChIP-ChIP_MESCs_Mouse1.65473485
32ZFP57_27257070_Chip-Seq_ESCs_Mouse1.65077438
33EZH2_22144423_ChIP-Seq_EOC_Human1.64455352
34SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.63788779
35TAF15_26573619_Chip-Seq_HEK293_Human1.61247156
36TP63_17297297_ChIP-ChIP_HaCaT_Human1.59752691
37VDR_22108803_ChIP-Seq_LS180_Human1.59663893
38EZH2_18974828_ChIP-Seq_MESCs_Mouse1.57619408
39RNF2_18974828_ChIP-Seq_MESCs_Mouse1.57619408
40RUNX1_27514584_Chip-Seq_MCF-7_Human1.57517042
41OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.56976650
42PIAS1_25552417_ChIP-Seq_VCAP_Human1.56837893
43TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.56522822
44SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.56502478
45ESR1_21235772_ChIP-Seq_MCF-7_Human1.55715858
46PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.55472552
47JARID2_20075857_ChIP-Seq_MESCs_Mouse1.54651296
48CBX2_27304074_Chip-Seq_ESCs_Mouse1.54134664
49TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.53211594
50MTF2_20144788_ChIP-Seq_MESCs_Mouse1.52139302
51TDRD3_21172665_ChIP-Seq_MCF-7_Human1.51641748
52RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.50512562
53CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.47520094
54YY1_22570637_ChIP-Seq_MALME-3M_Human1.45380882
55CTBP2_25329375_ChIP-Seq_LNCAP_Human1.45120781
56SMAD_19615063_ChIP-ChIP_OVARY_Human1.44882518
57CTBP1_25329375_ChIP-Seq_LNCAP_Human1.41946517
58PCGF2_27294783_Chip-Seq_NPCs_Mouse1.40379313
59POU3F2_20337985_ChIP-ChIP_501MEL_Human1.39866087
60CTCF_27219007_Chip-Seq_Bcells_Human1.39762744
61DROSHA_22980978_ChIP-Seq_HELA_Human1.38852965
62SMAD3_21741376_ChIP-Seq_EPCs_Human1.38734560
63P63_26484246_Chip-Seq_KERATINOCYTES_Human1.38510637
64SMAD4_21799915_ChIP-Seq_A2780_Human1.38191967
65TP63_22573176_ChIP-Seq_HFKS_Human1.37183586
66PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.36595845
67RNF2_27304074_Chip-Seq_NSC_Mouse1.35438819
68SUZ12_27294783_Chip-Seq_NPCs_Mouse1.35368119
69GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35155695
70SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.33920777
71P300_19829295_ChIP-Seq_ESCs_Human1.33045061
72KLF5_25053715_ChIP-Seq_YYC3_Human1.32768922
73TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.32691731
74FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.32468537
75GATA1_19941826_ChIP-Seq_K562_Human1.28888335
76PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.28113202
77CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.27973689
78TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27891325
79SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.26964771
80STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.26863934
81RNF2_27304074_Chip-Seq_ESCs_Mouse1.25317866
82RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.24462133
83RAD21_21589869_ChIP-Seq_MESCs_Mouse1.23556316
84SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.23308768
85NR3C1_21868756_ChIP-Seq_MCF10A_Human1.23058435
86AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.22884171
87EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.22591264
88NANOG_18555785_Chip-Seq_ESCs_Mouse1.22575250
89RUNX_20019798_ChIP-Seq_JUKART_Human1.22563055
90P68_20966046_ChIP-Seq_HELA_Human1.22363790
91LXR_22292898_ChIP-Seq_THP-1_Human1.22104748
92SMRT_27268052_Chip-Seq_Bcells_Human1.20600972
93SOX2_27498859_Chip-Seq_STOMACH_Mouse1.20484534
94KDM2B_26808549_Chip-Seq_SUP-B15_Human1.19819278
95TP53_18474530_ChIP-ChIP_U2OS_Human1.18830236
96TP63_23658742_ChIP-Seq_EP156T_Human1.18814448
97TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18456322
98CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.17699473
99ZNF217_24962896_ChIP-Seq_MCF-7_Human1.17173916
100CREB1_26743006_Chip-Seq_LNCaP_Human1.15690931
101LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15492676
102EZH2_27294783_Chip-Seq_NPCs_Mouse1.15304893
103PCGF2_27294783_Chip-Seq_ESCs_Mouse1.14959822
104RBPJ_22232070_ChIP-Seq_NCS_Mouse1.13815037
105EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.13757141
106SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.12222359
107P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12035550
108NFE2_27457419_Chip-Seq_LIVER_Mouse1.11625285
109VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.11559026
110PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.11454671
111KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.10617230
112IRF1_19129219_ChIP-ChIP_H3396_Human1.10344285
113ERG_21242973_ChIP-ChIP_JURKAT_Human1.10290179
114SUZ12_18555785_Chip-Seq_ESCs_Mouse1.10128394
115FUS_26573619_Chip-Seq_HEK293_Human1.09770512
116BCAT_22108803_ChIP-Seq_LS180_Human1.09737203
117P300_18555785_Chip-Seq_ESCs_Mouse1.08765217
118CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.08407929
119CMYC_18555785_Chip-Seq_ESCs_Mouse1.08404249
120SOX9_24532713_ChIP-Seq_HFSC_Mouse1.07601646
121PHF8_20622854_ChIP-Seq_HELA_Human1.07008092
122P53_22387025_ChIP-Seq_ESCs_Mouse1.06397214
123TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.06128382
124GATA1_26923725_Chip-Seq_HPCs_Mouse1.06050785
125* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.06006999
126SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.05784000
127TAL1_26923725_Chip-Seq_HPCs_Mouse1.04017333
128CRX_20693478_ChIP-Seq_RETINA_Mouse1.04014381
129PRDM14_20953172_ChIP-Seq_ESCs_Human1.02927627
130AHR_22903824_ChIP-Seq_MCF-7_Human1.02586992
131ARNT_22903824_ChIP-Seq_MCF-7_Human1.02358782
132P300_27268052_Chip-Seq_Bcells_Human1.01538098
133E2F1_20622854_ChIP-Seq_HELA_Human1.01408733
134E2F1_18555785_Chip-Seq_ESCs_Mouse1.00691125
135STAT3_18555785_Chip-Seq_ESCs_Mouse1.00353429
136CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.99673706
137STAT3_23295773_ChIP-Seq_U87_Human0.99584687
138RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.99329743
139ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.99048353
140TBL1_22424771_ChIP-Seq_293T_Human0.98991251
141EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.98990796
142SOX2_18555785_Chip-Seq_ESCs_Mouse0.98772147
143NRF2_20460467_ChIP-Seq_MEFs_Mouse0.98694791
144NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.98694791
145FLI1_27457419_Chip-Seq_LIVER_Mouse0.98569632
146BCOR_27268052_Chip-Seq_Bcells_Human0.98394729
147ZFX_18555785_Chip-Seq_ESCs_Mouse0.98129916
148TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97372244
149POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.97372244
150CTCF_20526341_ChIP-Seq_ESCs_Human0.97351900
151* SA1_27219007_Chip-Seq_ERYTHROID_Human0.96718595
152* RACK7_27058665_Chip-Seq_MCF-7_Human0.96670291
153FOXA1_25552417_ChIP-Seq_VCAP_Human0.96516078
154LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95878972
155SOX2_20726797_ChIP-Seq_SW620_Human0.95788833
156ETV1_20927104_ChIP-Seq_GIST48_Human0.95569223
157FOXM1_26456572_ChIP-Seq_MCF-7_Human0.95334956
158STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.95310244
159E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.93751462
160* MAF_26560356_Chip-Seq_TH1_Human0.93208005
161CTNNB1_20460455_ChIP-Seq_HCT116_Human0.91613078
162PPAR_26484153_Chip-Seq_NCI-H1993_Human0.91420214
163* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.91323862
164EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.90502389
165RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.90441809
166SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.88573174
167BCL6_27268052_Chip-Seq_Bcells_Human0.87668958
168FOXO3_23340844_ChIP-Seq_DLD1_Human0.87646607
169SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.87599117
170P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.87109096
171BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.86322622
172IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.82664916
173TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.82465410
174CEBPB_22108803_ChIP-Seq_LS180_Human0.81576444
175KDM2B_26808549_Chip-Seq_K562_Human0.81202571
176KDM2B_26808549_Chip-Seq_JURKAT_Human0.81048825
177SOX2_21211035_ChIP-Seq_LN229_Human0.80735609
178GATA2_19941826_ChIP-Seq_K562_Human0.80611427
179* CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.79114806
180MYC_27129775_Chip-Seq_CORNEA_Mouse0.77909947
181CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.77626767
182EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.76830078
183FLI1_21867929_ChIP-Seq_CD8_Mouse0.76344438
184TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.76158870
185* SA1_27219007_Chip-Seq_Bcells_Human0.75740810

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color8.10473750
2MP0008875_abnormal_xenobiotic_pharmacok5.69212662
3MP0004381_abnormal_hair_follicle4.54915030
4MP0001984_abnormal_olfaction3.45726945
5MP0003950_abnormal_plasma_membrane3.29069910
6MP0004043_abnormal_pH_regulation3.28527065
7MP0003303_peritoneal_inflammation3.27058373
8MP0000920_abnormal_myelination3.07348689
9MP0005623_abnormal_meninges_morphology2.70491239
10MP0008789_abnormal_olfactory_epithelium2.69089666
11MP0005409_darkened_coat_color2.58790798
12MP0004742_abnormal_vestibular_system2.55699278
13MP0003690_abnormal_glial_cell2.47492446
14MP0005377_hearing/vestibular/ear_phenot2.46559990
15MP0003878_abnormal_ear_physiology2.46559990
16MP0008004_abnormal_stomach_pH2.41621763
17MP0003656_abnormal_erythrocyte_physiolo2.16424684
18MP0003880_abnormal_central_pattern2.12755613
19MP0001485_abnormal_pinna_reflex2.06434304
20MP0000383_abnormal_hair_follicle2.00066343
21MP0004270_analgesia1.90974263
22MP0001851_eye_inflammation1.87960101
23MP0009046_muscle_twitch1.80114335
24MP0004133_heterotaxia1.77673176
25MP0010155_abnormal_intestine_physiology1.77276703
26MP0010678_abnormal_skin_adnexa1.72241268
27MP0003436_decreased_susceptibility_to1.71197924
28MP0002876_abnormal_thyroid_physiology1.70206013
29MP0003634_abnormal_glial_cell1.69265756
30MP0002168_other_aberrant_phenotype1.68612053
31MP0009780_abnormal_chondrocyte_physiolo1.68134374
32MP0003724_increased_susceptibility_to1.66934660
33MP0005394_taste/olfaction_phenotype1.63367125
34MP0005499_abnormal_olfactory_system1.63367125
35MP0002160_abnormal_reproductive_system1.62491983
36MP0001765_abnormal_ion_homeostasis1.60392832
37MP0002653_abnormal_ependyma_morphology1.57880484
38MP0002405_respiratory_system_inflammati1.56446823
39MP0001486_abnormal_startle_reflex1.56278518
40MP0004019_abnormal_vitamin_homeostasis1.55314232
41MP0009379_abnormal_foot_pigmentation1.51092933
42MP0002272_abnormal_nervous_system1.47841106
43MP0000778_abnormal_nervous_system1.47112834
44MP0004142_abnormal_muscle_tone1.46797736
45MP0005310_abnormal_salivary_gland1.46777568
46MP0001905_abnormal_dopamine_level1.46258151
47MP0003938_abnormal_ear_development1.45712994
48MP0001440_abnormal_grooming_behavior1.43446699
49MP0001188_hyperpigmentation1.41960853
50MP0002064_seizures1.41606580
51MP0002796_impaired_skin_barrier1.40995577
52MP0006082_CNS_inflammation1.39924189
53MP0005165_increased_susceptibility_to1.36340578
54MP0005379_endocrine/exocrine_gland_phen1.32877734
55MP0003329_amyloid_beta_deposits1.28786890
56MP0001986_abnormal_taste_sensitivity1.28615421
57MP0005451_abnormal_body_composition1.28496406
58MP0002249_abnormal_larynx_morphology1.27542082
59MP0005646_abnormal_pituitary_gland1.26086760
60MP0005551_abnormal_eye_electrophysiolog1.24849567
61MP0000465_gastrointestinal_hemorrhage1.24657126
62MP0002734_abnormal_mechanical_nocicepti1.24312944
63MP0005423_abnormal_somatic_nervous1.23749232
64MP0003075_altered_response_to1.23668178
65MP0009278_abnormal_bone_marrow1.23630267
66MP0003937_abnormal_limbs/digits/tail_de1.23463290
67MP0001663_abnormal_digestive_system1.21992071
68MP0001790_abnormal_immune_system1.21736084
69MP0005387_immune_system_phenotype1.21736084
70MP0009384_cardiac_valve_regurgitation1.20349792
71MP0004264_abnormal_extraembryonic_tissu1.19674650
72MP0000462_abnormal_digestive_system1.19152078
73MP0001968_abnormal_touch/_nociception1.15204404
74MP0009764_decreased_sensitivity_to1.14528145
75MP0005388_respiratory_system_phenotype1.14060601
76MP0002133_abnormal_respiratory_system1.14060601
77MP0004885_abnormal_endolymph1.14023770
78MP0001501_abnormal_sleep_pattern1.13894744
79MP0002638_abnormal_pupillary_reflex1.13788666
80MP0002938_white_spotting1.12400398
81MP0002277_abnormal_respiratory_mucosa1.10512695
82MP0006292_abnormal_olfactory_placode1.10360764
83MP0009765_abnormal_xenobiotic_induced1.09755093
84MP0005025_abnormal_response_to1.09181448
85MP0002148_abnormal_hypersensitivity_rea1.08530139
86MP0002098_abnormal_vibrissa_morphology1.08112428
87MP0002282_abnormal_trachea_morphology1.06731933
88MP0005164_abnormal_response_to1.04799334
89MP0000026_abnormal_inner_ear1.03259735
90MP0000762_abnormal_tongue_morphology1.02935962
91MP0000647_abnormal_sebaceous_gland1.01126047
92MP0002229_neurodegeneration0.99662324
93MP0001727_abnormal_embryo_implantation0.99461974
94MP0009250_abnormal_appendicular_skeleto0.98495449
95MP0000858_altered_metastatic_potential0.95917214
96MP0009745_abnormal_behavioral_response0.95873526
97MP0005171_absent_coat_pigmentation0.95678795
98MP0002928_abnormal_bile_duct0.95549961
99MP0002419_abnormal_innate_immunity0.95325213
100MP0005389_reproductive_system_phenotype0.94966248
101MP0001963_abnormal_hearing_physiology0.94670535
102MP0001340_abnormal_eyelid_morphology0.92445486
103MP0003866_abnormal_defecation0.90886669
104MP0001533_abnormal_skeleton_physiology0.90561733
105MP0001177_atelectasis0.89557016
106MP0002136_abnormal_kidney_physiology0.89280627
107MP0005636_abnormal_mineral_homeostasis0.89260096
108MP0002909_abnormal_adrenal_gland0.89191745
109MP0004883_abnormal_blood_vessel0.89114895
110MP0001502_abnormal_circadian_rhythm0.88661803
111MP0002752_abnormal_somatic_nervous0.88372678
112MP0001529_abnormal_vocalization0.88105806
113MP0009785_altered_susceptibility_to0.87987874
114MP0002332_abnormal_exercise_endurance0.87420423
115MP0004947_skin_inflammation0.86889500
116MP0002572_abnormal_emotion/affect_behav0.86057059
117MP0003191_abnormal_cellular_cholesterol0.85840547
118MP0000470_abnormal_stomach_morphology0.85141142
119MP0003635_abnormal_synaptic_transmissio0.84342804
120MP0001970_abnormal_pain_threshold0.83538731
121MP0001845_abnormal_inflammatory_respons0.83254457
122MP0000049_abnormal_middle_ear0.83040128
123MP0000579_abnormal_nail_morphology0.82667728
124MP0002882_abnormal_neuron_morphology0.82238101
125MP0000678_abnormal_parathyroid_gland0.81930716
126MP0009763_increased_sensitivity_to0.81691486
127MP0005083_abnormal_biliary_tract0.81472790
128MP0000467_abnormal_esophagus_morphology0.81315772
129MP0002102_abnormal_ear_morphology0.81187836
130MP0000613_abnormal_salivary_gland0.80614929
131MP0003011_delayed_dark_adaptation0.79790566
132MP0002067_abnormal_sensory_capabilities0.79746334
133MP0001661_extended_life_span0.79176773
134MP0009643_abnormal_urine_homeostasis0.78433296
135MP0002723_abnormal_immune_serum0.77003553
136MP0002452_abnormal_antigen_presenting0.76574178
137MP0002557_abnormal_social/conspecific_i0.74373169
138MP0000377_abnormal_hair_follicle0.74272035
139MP0002295_abnormal_pulmonary_circulatio0.73665736
140MP0001346_abnormal_lacrimal_gland0.73544716
141MP0002736_abnormal_nociception_after0.73098877
142MP0000566_synostosis0.73065089
143MP0005166_decreased_susceptibility_to0.72250076
144MP0001324_abnormal_eye_pigmentation0.72028369
145MP0005395_other_phenotype0.71070850
146MP0000631_abnormal_neuroendocrine_gland0.71058418
147MP0001800_abnormal_humoral_immune0.70365812
148MP0005381_digestive/alimentary_phenotyp0.70205308
149MP0004272_abnormal_basement_membrane0.69828365
150MP0005410_abnormal_fertilization0.69228974
151MP0005000_abnormal_immune_tolerance0.68358610
152MP0005248_abnormal_Harderian_gland0.67905344
153MP0003453_abnormal_keratinocyte_physiol0.67449376
154MP0000249_abnormal_blood_vessel0.67237379
155MP0002132_abnormal_respiratory_system0.66534244
156MP0002822_catalepsy0.65912003
157MP0002066_abnormal_motor_capabilities/c0.64546362
158MP0006072_abnormal_retinal_apoptosis0.64456991
159MP0005023_abnormal_wound_healing0.64209245
160MP0003632_abnormal_nervous_system0.63947656
161MP0001853_heart_inflammation0.63751909
162MP0001835_abnormal_antigen_presentation0.63651211
163MP0000955_abnormal_spinal_cord0.62875686
164MP0010771_integument_phenotype0.62765500
165MP0005275_abnormal_skin_tensile0.61498430
166MP0001958_emphysema0.60859342
167MP0002735_abnormal_chemical_nociception0.60337037
168MP0001293_anophthalmia0.60151173
169MP0006276_abnormal_autonomic_nervous0.60117094
170MP0005195_abnormal_posterior_eye0.60113744
171MP0001819_abnormal_immune_cell0.58788275
172MP0000685_abnormal_immune_system0.56700021
173MP0002420_abnormal_adaptive_immunity0.56238147
174MP0005671_abnormal_response_to0.55563141
175MP0005167_abnormal_blood-brain_barrier0.55042351

Predicted human phenotypes

RankGene SetZ-score
1Rhinitis (HP:0012384)8.67450691
2Abnormal respiratory motile cilium morphology (HP:0005938)8.34079173
3Abnormal respiratory epithelium morphology (HP:0012253)8.34079173
4Absent/shortened dynein arms (HP:0200106)6.78625122
5Dynein arm defect of respiratory motile cilia (HP:0012255)6.78625122
6Chronic bronchitis (HP:0004469)5.01936266
7Bronchiectasis (HP:0002110)4.90843216
8Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.99777686
9Degeneration of the lateral corticospinal tracts (HP:0002314)3.99777686
10Parakeratosis (HP:0001036)3.62235999
11Nasal polyposis (HP:0100582)3.40176190
12Recurrent sinusitis (HP:0011108)3.38628906
13True hermaphroditism (HP:0010459)3.22381429
14Chronic sinusitis (HP:0011109)3.20967342
15Chronic otitis media (HP:0000389)3.17275051
16Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.14711349
17Pancreatic fibrosis (HP:0100732)2.96487060
18Neurofibrillary tangles (HP:0002185)2.86705271
19Abnormality of the nasal mucosa (HP:0000433)2.80242004
20Hyperactive renin-angiotensin system (HP:0000841)2.79497819
21Abnormality of the corticospinal tract (HP:0002492)2.67209207
22Abnormal sex determination (HP:0012244)2.56926488
23Sex reversal (HP:0012245)2.56926488
24Asplenia (HP:0001746)2.53404865
25Bronchitis (HP:0012387)2.51589211
26Medial flaring of the eyebrow (HP:0010747)2.48791325
27Median cleft lip (HP:0000161)2.43690701
28Nephronophthisis (HP:0000090)2.43262901
29Gait imbalance (HP:0002141)2.38543040
30Sensory axonal neuropathy (HP:0003390)2.36807638
31Congenital primary aphakia (HP:0007707)2.27315044
32Aplasia/Hypoplasia of the spleen (HP:0010451)2.26060464
33Atelectasis (HP:0100750)2.24802939
34Peripheral hypomyelination (HP:0007182)2.21750796
35Congenital ichthyosiform erythroderma (HP:0007431)2.20326606
36Pancreatic cysts (HP:0001737)2.19696021
37Genital tract atresia (HP:0001827)2.17176827
38Tubulointerstitial nephritis (HP:0001970)2.16660478
39Abnormality of midbrain morphology (HP:0002418)2.12380077
40Molar tooth sign on MRI (HP:0002419)2.12380077
41Abnormality of the dental root (HP:0006486)2.08007593
42Taurodontia (HP:0000679)2.08007593
43Abnormality of permanent molar morphology (HP:0011071)2.08007593
44Concave nail (HP:0001598)2.07378918
45Occipital encephalocele (HP:0002085)2.07179427
46Vaginal atresia (HP:0000148)2.07156837
47Termporal pattern (HP:0011008)2.06792109
48Insidious onset (HP:0003587)2.06792109
49Recurrent bronchitis (HP:0002837)2.05703322
50Abnormal umbilical cord blood vessels (HP:0011403)2.04768709
51Single umbilical artery (HP:0001195)2.04768709
52Abnormality of the fetal cardiovascular system (HP:0010948)2.04768709
53Chronic hepatic failure (HP:0100626)2.03676217
54Abnormality of molar (HP:0011077)2.02590726
55Abnormality of molar morphology (HP:0011070)2.02590726
56Recurrent otitis media (HP:0000403)2.01738255
57Abnormal ciliary motility (HP:0012262)10.9230216
58Abnormal respiratory motile cilium physiology (HP:0012261)10.4886480
59Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.1921937
60Decreased circulating renin level (HP:0003351)1.99695764
61Absent frontal sinuses (HP:0002688)1.99690355
62Nephrogenic diabetes insipidus (HP:0009806)1.95215771
63Infertility (HP:0000789)1.95177465
64Male pseudohermaphroditism (HP:0000037)1.94884072
65Abnormality of the dental pulp (HP:0006479)1.93221725
66Bile duct proliferation (HP:0001408)1.92204762
67Abnormal biliary tract physiology (HP:0012439)1.92204762
68Abnormality of the renal medulla (HP:0100957)1.89269395
69Stage 5 chronic kidney disease (HP:0003774)1.85257225
70Postaxial foot polydactyly (HP:0001830)1.83243090
71Abnormality of dentin (HP:0010299)1.81884014
72Anencephaly (HP:0002323)1.76728762
73Adrenal hypoplasia (HP:0000835)1.75549991
74Cerebral inclusion bodies (HP:0100314)1.74363934
75Nephropathy (HP:0000112)1.68746636
76Onion bulb formation (HP:0003383)1.66387342
77Supernumerary spleens (HP:0009799)1.66037292
78Renal salt wasting (HP:0000127)1.65724579
79Congenital hepatic fibrosis (HP:0002612)1.62227851
80Oculomotor apraxia (HP:0000657)1.58839429
81Tubular atrophy (HP:0000092)1.57535341
82Aplasia/Hypoplasia of the tongue (HP:0010295)1.57381194
83Decreased central vision (HP:0007663)1.57223781
84Bell-shaped thorax (HP:0001591)1.56794967
85Stomatitis (HP:0010280)1.56145163
86Retinal dysplasia (HP:0007973)1.55589464
87Esophageal neoplasm (HP:0100751)1.55302676
88Neoplasm of head and neck (HP:0012288)1.55302676
89Poor coordination (HP:0002370)1.55201739
90Furrowed tongue (HP:0000221)1.54256615
91Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.54089109
92Autoimmune hemolytic anemia (HP:0001890)1.52880552
93Fibular hypoplasia (HP:0003038)1.51712464
94Obstructive sleep apnea (HP:0002870)1.51515498
95Postaxial hand polydactyly (HP:0001162)1.51218713
96Cystic liver disease (HP:0006706)1.50312385
97Ectopic anus (HP:0004397)1.49707027
98Male infertility (HP:0003251)1.46688897
99Abnormal pupillary function (HP:0007686)1.46468197
100Aplasia/Hypoplasia of the lens (HP:0008063)1.46241952
101Carpal bone hypoplasia (HP:0001498)1.44931993
102Tubulointerstitial abnormality (HP:0001969)1.44828805
103Absent septum pellucidum (HP:0001331)1.44295321
104Bifid scrotum (HP:0000048)1.43393358
105Septo-optic dysplasia (HP:0100842)1.43199911
106Preaxial hand polydactyly (HP:0001177)1.41488949
107Supranuclear gaze palsy (HP:0000605)1.41377959
108Bronchomalacia (HP:0002780)1.40936741
109Erythroderma (HP:0001019)1.40857868
110Fetal akinesia sequence (HP:0001989)1.40035943
111Intention tremor (HP:0002080)1.38815357
112Short femoral neck (HP:0100864)1.37545211
113Abnormality of secondary sexual hair (HP:0009888)1.37105485
114Abnormality of the axillary hair (HP:0100134)1.37105485
115Abnormality of renin-angiotensin system (HP:0000847)1.36920224
116Back pain (HP:0003418)1.35380588
117Metabolic alkalosis (HP:0200114)1.34843868
118Abnormality of the frontal sinuses (HP:0002687)1.34790433
119Sclerocornea (HP:0000647)1.34330855
120Hyperaldosteronism (HP:0000859)1.33658827
121Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.32305232
122Abnormality of the distal phalanges of the toes (HP:0010182)1.32258836
123Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.30450228
124Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.29977040
125Absent rod-and cone-mediated responses on ERG (HP:0007688)1.28181965
126Hyperkalemia (HP:0002153)1.25839909
127Aplasia/Hypoplasia of the sacrum (HP:0008517)1.25503306
128Short nail (HP:0001799)1.23662277
129Abnormality of chloride homeostasis (HP:0011422)1.23193824
130Flat acetabular roof (HP:0003180)1.23064945
131Elevated erythrocyte sedimentation rate (HP:0003565)1.21196120
132Spinal muscular atrophy (HP:0007269)1.20422595
133Short thorax (HP:0010306)1.19881497
134Aplasia of the musculature (HP:0100854)1.18730522
135Aplasia/hypoplasia of the femur (HP:0005613)1.16298809
136Alveolar cell carcinoma (HP:0006519)1.15642396
137Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.14741315
138Hypokalemic alkalosis (HP:0001949)1.12150492
139Self-mutilation (HP:0000742)1.07327296
140Muscle fiber splitting (HP:0003555)1.04138305
141Stridor (HP:0010307)1.02696756
142Neoplasm of the tracheobronchial system (HP:0100552)1.02221652
143Down-sloping shoulders (HP:0200021)1.00059800
144Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)0.99709291
145Popliteal pterygium (HP:0009756)0.97496346
146Abnormality of the middle phalanges of the toes (HP:0010183)0.95493408
147Abnormal drinking behavior (HP:0030082)0.95283471

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK155.42284604
2MST44.15207484
3EPHA24.11759096
4PNCK3.85412121
5STK393.77513471
6OXSR12.99358544
7CASK2.76526541
8STK242.40399184
9EPHB12.28311283
10BCR2.16047074
11GRK12.14705525
12TNIK2.06035711
13MAPKAPK52.01175162
14PKN11.94770519
15CAMKK21.77976807
16MAP3K31.77134708
17BLK1.63539863
18MAP2K21.63033895
19IRAK41.61194815
20SMG11.57128682
21ROCK21.49795566
22FGR1.49470066
23LRRK21.49041945
24CAMKK11.45408466
25MAPKAPK31.44382454
26TBK11.42786977
27RIPK41.39609134
28PBK1.38392218
29CDK31.32302877
30NEK61.30650032
31PTK2B1.25448633
32TRPM71.25214151
33WNK41.25076027
34TXK1.24641711
35CDK191.21738897
36IRAK11.19745671
37GRK61.19327784
38CSNK1G31.18625603
39CSNK1A1L1.15934082
40MATK1.15001179
41CSNK1G11.14822865
42WNK11.13913875
43CAMK2B1.13314608
44STK161.11974196
45PAK21.11211627
46MAP3K71.10313490
47STK101.09411481
48MET1.09330352
49MAP3K111.09299670
50MAP3K41.04618081
51NLK1.02350063
52DYRK21.02003487
53ZAP701.01890192
54NTRK20.99797132
55PAK30.98066258
56IKBKE0.96541257
57CLK10.95783859
58GSK3A0.92690112
59TAOK10.92411310
60PRKCE0.92273181
61PHKG20.91335245
62PHKG10.91335245
63IRAK20.91332503
64MUSK0.87775734
65FGFR20.87381693
66UHMK10.86802259
67MAP3K140.86380747
68CAMK2D0.85502772
69ITK0.84923872
70PRKCQ0.83487383
71MAP2K40.82424738
72MAP2K30.81991847
73DYRK1B0.79664639
74NTRK10.78544285
75FES0.77276973
76BMPR1B0.75703868
77CHUK0.75170607
78CAMK2G0.74107703
79VRK10.73491967
80SIK20.72282283
81ADRBK20.71994128
82RPS6KA50.71388007
83CSK0.70404287
84CAMK2A0.70356979
85ARAF0.68995149
86ICK0.68360227
87MAP3K60.68103118
88MARK10.67559079
89MAP4K10.65667590
90PIM20.64219885
91PAK60.63075747
92GRK70.62824077
93MKNK20.62786265
94CSNK1G20.62724239
95ERBB20.62401851
96PRKCD0.60449208
97DMPK0.58901362
98SGK10.58036739
99PRKG10.57742993
100FYN0.57680840
101IKBKB0.56097107
102TGFBR20.56047091
103EPHA30.54476891
104MAP3K20.53934998
105CDK50.53758105
106TYK20.53745593
107PRKD20.52270946
108ROCK10.52120687
109PRKCI0.51783852
110SGK4940.51716883
111SGK2230.51716883
112ABL20.51495633
113TLK10.51096390
114LIMK10.50378154
115FER0.49584335
116MAP2K60.49276552
117ERBB40.47290143
118MARK20.47241571
119EPHA40.47001101
120MAPK70.46816365
121IRAK30.46008077
122EEF2K0.45860353
123DYRK1A0.45124727
124AURKA0.44933311
125ADRBK10.44821789
126BMPR20.44812272
127PRKD10.43850230
128PRKCG0.42800491
129PRKAA20.42500098
130CDC42BPA0.42484907
131MAP3K130.42173211
132PRPF4B0.42158601
133HIPK20.42002951
134RPS6KA20.39915504
135BTK0.38344830
136MKNK10.38271657
137PRKACA0.37671999
138MOS0.37318730
139PASK0.36821834
140CSNK1D0.36530754
141ABL10.34436260
142MAPK120.33522872
143LCK0.33250465
144NME10.32683941
145MAPKAPK20.32153855
146PDPK10.31998845
147CDK140.31447109
148EPHB20.31068872
149SGK30.30789111
150TTK0.30030606
151LYN0.29251341
152DYRK30.26015657
153PRKCZ0.25286531
154TAOK20.25283387
155PDK10.23151017
156MAP3K10.22442642
157RPS6KA60.21565511
158STK380.20938657
159MST1R0.20138211
160MAP3K120.20031177
161CAMK10.19392927

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.78123897
2Phenylalanine metabolism_Homo sapiens_hsa003603.72398180
3Fatty acid elongation_Homo sapiens_hsa000623.03707392
4Ether lipid metabolism_Homo sapiens_hsa005652.84643295
5Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.80974322
6Steroid biosynthesis_Homo sapiens_hsa001002.54038876
7Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.36849611
8Histidine metabolism_Homo sapiens_hsa003402.32259172
9Oxidative phosphorylation_Homo sapiens_hsa001902.18188216
10Vitamin B6 metabolism_Homo sapiens_hsa007502.14213257
11Sphingolipid metabolism_Homo sapiens_hsa006002.03876415
12Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.03155332
13Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.95152115
14Protein export_Homo sapiens_hsa030601.92462916
15Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.80881501
16beta-Alanine metabolism_Homo sapiens_hsa004101.79267929
17Sulfur metabolism_Homo sapiens_hsa009201.77059422
18Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.67555751
19Huntingtons disease_Homo sapiens_hsa050161.63949585
20Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.63604167
21Phototransduction_Homo sapiens_hsa047441.55265986
22Notch signaling pathway_Homo sapiens_hsa043301.55145411
23Caffeine metabolism_Homo sapiens_hsa002321.54309403
24Butanoate metabolism_Homo sapiens_hsa006501.48762143
25Axon guidance_Homo sapiens_hsa043601.48757597
26Alzheimers disease_Homo sapiens_hsa050101.47125238
27Graft-versus-host disease_Homo sapiens_hsa053321.41787267
28Linoleic acid metabolism_Homo sapiens_hsa005911.41024364
29Collecting duct acid secretion_Homo sapiens_hsa049661.37323079
30Arachidonic acid metabolism_Homo sapiens_hsa005901.34911244
31Parkinsons disease_Homo sapiens_hsa050121.30195230
32Toll-like receptor signaling pathway_Homo sapiens_hsa046201.27515992
33TNF signaling pathway_Homo sapiens_hsa046681.24889683
34Serotonergic synapse_Homo sapiens_hsa047261.23806140
35RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.23202578
36Rheumatoid arthritis_Homo sapiens_hsa053231.22928101
37Hepatitis C_Homo sapiens_hsa051601.19507247
38Retinol metabolism_Homo sapiens_hsa008301.16010275
39Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.15612614
40Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.14959006
41Autoimmune thyroid disease_Homo sapiens_hsa053201.14056983
42Ovarian steroidogenesis_Homo sapiens_hsa049131.12174689
43alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.11778122
44Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.11411337
45NOD-like receptor signaling pathway_Homo sapiens_hsa046211.10891095
46Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.10623582
47GABAergic synapse_Homo sapiens_hsa047271.09306905
48Cocaine addiction_Homo sapiens_hsa050301.03869500
49Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.03294578
50Vibrio cholerae infection_Homo sapiens_hsa051101.02281010
51Glutamatergic synapse_Homo sapiens_hsa047241.02002530
52Glutathione metabolism_Homo sapiens_hsa004801.00490452
53Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.00209394
54ABC transporters_Homo sapiens_hsa020100.96708246
55Gastric acid secretion_Homo sapiens_hsa049710.92699287
56Glycosaminoglycan degradation_Homo sapiens_hsa005310.91987393
57NF-kappa B signaling pathway_Homo sapiens_hsa040640.91239448
58Arginine and proline metabolism_Homo sapiens_hsa003300.91051680
59Osteoclast differentiation_Homo sapiens_hsa043800.90165288
60Carbohydrate digestion and absorption_Homo sapiens_hsa049730.88919008
61Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.88477971
62Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.87992387
63Nicotine addiction_Homo sapiens_hsa050330.86994775
64Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.86945755
65Chemical carcinogenesis_Homo sapiens_hsa052040.85729802
66Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.85727678
67Renal cell carcinoma_Homo sapiens_hsa052110.85555075
68Leishmaniasis_Homo sapiens_hsa051400.84311437
69Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.84280185
70Long-term depression_Homo sapiens_hsa047300.79517912
71Vascular smooth muscle contraction_Homo sapiens_hsa042700.78790616
72Phagosome_Homo sapiens_hsa041450.76728682
73Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.75600724
74Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.74978699
75Morphine addiction_Homo sapiens_hsa050320.73640765
76Mineral absorption_Homo sapiens_hsa049780.72665132
77Lysosome_Homo sapiens_hsa041420.72637637
78Renin secretion_Homo sapiens_hsa049240.72095730
79Peroxisome_Homo sapiens_hsa041460.70610443
80Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.70192462
81Taste transduction_Homo sapiens_hsa047420.69910679
82Salivary secretion_Homo sapiens_hsa049700.68789270
83Amoebiasis_Homo sapiens_hsa051460.67838518
84Malaria_Homo sapiens_hsa051440.67470639
85Hedgehog signaling pathway_Homo sapiens_hsa043400.67447184
86Tight junction_Homo sapiens_hsa045300.67194499
87Jak-STAT signaling pathway_Homo sapiens_hsa046300.66393654
88Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65336786
89Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.64212393
90Wnt signaling pathway_Homo sapiens_hsa043100.64168678
91Salmonella infection_Homo sapiens_hsa051320.64122475
92Legionellosis_Homo sapiens_hsa051340.63854513
93Amphetamine addiction_Homo sapiens_hsa050310.63804548
94Ras signaling pathway_Homo sapiens_hsa040140.62428081
95Calcium signaling pathway_Homo sapiens_hsa040200.62224164
96Steroid hormone biosynthesis_Homo sapiens_hsa001400.61451750
97Vitamin digestion and absorption_Homo sapiens_hsa049770.61310546
98Intestinal immune network for IgA production_Homo sapiens_hsa046720.60766775
99Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.60741250
100Choline metabolism in cancer_Homo sapiens_hsa052310.59968517
101Prion diseases_Homo sapiens_hsa050200.59770905
102Sphingolipid signaling pathway_Homo sapiens_hsa040710.59521195
103Tuberculosis_Homo sapiens_hsa051520.59418450
104Pertussis_Homo sapiens_hsa051330.58920831
105SNARE interactions in vesicular transport_Homo sapiens_hsa041300.58635609
106Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.58357573
107Circadian entrainment_Homo sapiens_hsa047130.57754309
108Melanogenesis_Homo sapiens_hsa049160.56841565
109Influenza A_Homo sapiens_hsa051640.56194252
110Cardiac muscle contraction_Homo sapiens_hsa042600.56108134
111Glycerophospholipid metabolism_Homo sapiens_hsa005640.55844776
112Tyrosine metabolism_Homo sapiens_hsa003500.55679009
113Apoptosis_Homo sapiens_hsa042100.54977042
114Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.54933515
115Hematopoietic cell lineage_Homo sapiens_hsa046400.54032377
116Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.52904339
117Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.52446128
118Type I diabetes mellitus_Homo sapiens_hsa049400.51515825
119Basal cell carcinoma_Homo sapiens_hsa052170.49914940
120Regulation of autophagy_Homo sapiens_hsa041400.49487081
121Staphylococcus aureus infection_Homo sapiens_hsa051500.49329064
122ECM-receptor interaction_Homo sapiens_hsa045120.47502165
123Transcriptional misregulation in cancer_Homo sapiens_hsa052020.47191476
124cAMP signaling pathway_Homo sapiens_hsa040240.46996383
125Neurotrophin signaling pathway_Homo sapiens_hsa047220.46923439
126Chemokine signaling pathway_Homo sapiens_hsa040620.45693720
127Pancreatic secretion_Homo sapiens_hsa049720.45588800
128Fatty acid degradation_Homo sapiens_hsa000710.45400954
129Asthma_Homo sapiens_hsa053100.45107178
130Olfactory transduction_Homo sapiens_hsa047400.44587838
131MAPK signaling pathway_Homo sapiens_hsa040100.44138600
132Toxoplasmosis_Homo sapiens_hsa051450.43623033
133Maturity onset diabetes of the young_Homo sapiens_hsa049500.43546524
134Circadian rhythm_Homo sapiens_hsa047100.43081927
135GnRH signaling pathway_Homo sapiens_hsa049120.42942410
136Leukocyte transendothelial migration_Homo sapiens_hsa046700.42560716
137Allograft rejection_Homo sapiens_hsa053300.41369029
138Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.40416293
139Starch and sucrose metabolism_Homo sapiens_hsa005000.39842640
140Dorso-ventral axis formation_Homo sapiens_hsa043200.39098174
141Metabolic pathways_Homo sapiens_hsa011000.38750095
142Drug metabolism - other enzymes_Homo sapiens_hsa009830.38574919
143Complement and coagulation cascades_Homo sapiens_hsa046100.38524244
144T cell receptor signaling pathway_Homo sapiens_hsa046600.38326433
145Acute myeloid leukemia_Homo sapiens_hsa052210.37751217
146Measles_Homo sapiens_hsa051620.37504307
147Other glycan degradation_Homo sapiens_hsa005110.36921433
148Insulin resistance_Homo sapiens_hsa049310.36287692

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