

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | axonemal dynein complex assembly (GO:0070286) | 6.08553998 |
| 2 | peptidyl-histidine modification (GO:0018202) | 5.25857936 |
| 3 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 4.96849922 |
| 4 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 4.81007655 |
| 5 | negative regulation of cell cycle arrest (GO:0071157) | 4.48093465 |
| 6 | chaperone-mediated protein transport (GO:0072321) | 4.45994862 |
| 7 | protein neddylation (GO:0045116) | 4.19875730 |
| 8 | protein deneddylation (GO:0000338) | 4.02778772 |
| 9 | base-excision repair, AP site formation (GO:0006285) | 3.84591395 |
| 10 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.79190568 |
| 11 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.71063086 |
| 12 | cotranslational protein targeting to membrane (GO:0006613) | 3.70814522 |
| 13 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.68599254 |
| 14 | spinal cord motor neuron differentiation (GO:0021522) | 3.68381021 |
| 15 | ribosomal small subunit assembly (GO:0000028) | 3.65360135 |
| 16 | protein targeting to ER (GO:0045047) | 3.59506627 |
| 17 | intraciliary transport (GO:0042073) | 3.58006875 |
| 18 | chondrocyte proliferation (GO:0035988) | 3.56983480 |
| 19 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.56824605 |
| 20 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.56824605 |
| 21 | NADH dehydrogenase complex assembly (GO:0010257) | 3.56824605 |
| 22 | ATP synthesis coupled proton transport (GO:0015986) | 3.52111720 |
| 23 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.52111720 |
| 24 | regulation of helicase activity (GO:0051095) | 3.50737355 |
| 25 | cullin deneddylation (GO:0010388) | 3.48397187 |
| 26 | viral transcription (GO:0019083) | 3.45224077 |
| 27 | protein localization to endoplasmic reticulum (GO:0070972) | 3.43391905 |
| 28 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.43254238 |
| 29 | DNA damage response, detection of DNA damage (GO:0042769) | 3.42674307 |
| 30 | translational termination (GO:0006415) | 3.38266836 |
| 31 | growth hormone secretion (GO:0030252) | 3.35936035 |
| 32 | cell differentiation in spinal cord (GO:0021515) | 3.35626990 |
| 33 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 3.30809371 |
| 34 | IMP biosynthetic process (GO:0006188) | 3.28533856 |
| 35 | protein complex biogenesis (GO:0070271) | 3.24903737 |
| 36 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.17393578 |
| 37 | IMP metabolic process (GO:0046040) | 3.15663013 |
| 38 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.15541946 |
| 39 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.14898937 |
| 40 | axon extension involved in axon guidance (GO:0048846) | 3.14898937 |
| 41 | skeletal muscle tissue regeneration (GO:0043403) | 3.08924428 |
| 42 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.06094168 |
| 43 | oxidative phosphorylation (GO:0006119) | 3.04322220 |
| 44 | dorsal/ventral neural tube patterning (GO:0021904) | 2.99166370 |
| 45 | DNA strand renaturation (GO:0000733) | 2.98034420 |
| 46 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 2.94161723 |
| 47 | translational elongation (GO:0006414) | 2.91073226 |
| 48 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.89060397 |
| 49 | mitochondrial RNA metabolic process (GO:0000959) | 2.88996156 |
| 50 | translational initiation (GO:0006413) | 2.88686771 |
| 51 | epithelial cilium movement (GO:0003351) | 2.85743151 |
| 52 | transcription elongation from RNA polymerase II promoter (GO:0006368) | 2.85307076 |
| 53 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.83270044 |
| 54 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.81844013 |
| 55 | termination of RNA polymerase III transcription (GO:0006386) | 2.81844013 |
| 56 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.81796319 |
| 57 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.81796319 |
| 58 | protein targeting to membrane (GO:0006612) | 2.81039850 |
| 59 | protein localization to Golgi apparatus (GO:0034067) | 2.80757586 |
| 60 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.79737405 |
| 61 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.78266103 |
| 62 | intracellular protein transmembrane import (GO:0044743) | 2.78187808 |
| 63 | respiratory electron transport chain (GO:0022904) | 2.76317725 |
| 64 | histone H4-K12 acetylation (GO:0043983) | 2.73951885 |
| 65 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 2.73888645 |
| 66 | short-term memory (GO:0007614) | 2.72523067 |
| 67 | electron transport chain (GO:0022900) | 2.71248785 |
| 68 | translation (GO:0006412) | 2.70842691 |
| 69 | spinal cord association neuron differentiation (GO:0021527) | 2.70100295 |
| 70 | sulfate transmembrane transport (GO:1902358) | 2.68024340 |
| 71 | protein polyglutamylation (GO:0018095) | 2.67484367 |
| 72 | localization within membrane (GO:0051668) | 2.67074695 |
| 73 | proteasome assembly (GO:0043248) | 2.65659447 |
| 74 | platelet dense granule organization (GO:0060155) | 2.65263682 |
| 75 | negative regulation of Notch signaling pathway (GO:0045746) | 2.64976187 |
| 76 | tRNA aminoacylation for protein translation (GO:0006418) | 2.62470346 |
| 77 | positive regulation of gastrulation (GO:2000543) | 2.60682588 |
| 78 | sperm motility (GO:0030317) | 2.60534696 |
| 79 | retinal ganglion cell axon guidance (GO:0031290) | 2.60113761 |
| 80 | metallo-sulfur cluster assembly (GO:0031163) | 2.58791722 |
| 81 | iron-sulfur cluster assembly (GO:0016226) | 2.58791722 |
| 82 | DNA-templated transcription, elongation (GO:0006354) | 2.58539257 |
| 83 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.57926152 |
| 84 | resolution of meiotic recombination intermediates (GO:0000712) | 2.56151251 |
| 85 | regulation of telomere maintenance via telomerase (GO:0032210) | 2.56125038 |
| 86 | tRNA modification (GO:0006400) | 2.55961556 |
| 87 | male meiosis (GO:0007140) | 2.55684069 |
| 88 | cellular protein complex disassembly (GO:0043624) | 2.55190645 |
| 89 | AMP metabolic process (GO:0046033) | 2.54763415 |
| 90 | protein insertion into membrane (GO:0051205) | 2.54168998 |
| 91 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.53819241 |
| 92 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 2.53664146 |
| 93 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.53523572 |
| 94 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.53523572 |
| 95 | protein targeting to mitochondrion (GO:0006626) | 2.52485422 |
| 96 | retina layer formation (GO:0010842) | 2.52068364 |
| 97 | positive regulation of prostaglandin secretion (GO:0032308) | 2.51508630 |
| 98 | cell proliferation in forebrain (GO:0021846) | 2.50766493 |
| 99 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 2.49651158 |
| 100 | mismatch repair (GO:0006298) | 2.46921175 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.28900869 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.16310881 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.88127840 |
| 4 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.24566052 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.05513692 |
| 6 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.82387921 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.81651079 |
| 8 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.79985504 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.63785544 |
| 10 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.63386849 |
| 11 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.53601936 |
| 12 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.50568045 |
| 13 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.18651734 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.13167894 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.10103868 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.06033275 |
| 17 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.03688082 |
| 18 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.02288819 |
| 19 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 2.01094629 |
| 20 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.99610791 |
| 21 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.96017141 |
| 22 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.91830434 |
| 23 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.90880452 |
| 24 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.87845265 |
| 25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.86174711 |
| 26 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.81712246 |
| 27 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.79851371 |
| 28 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.71728195 |
| 29 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.70216754 |
| 30 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.69762157 |
| 31 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.68286753 |
| 32 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.62417140 |
| 33 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.59160364 |
| 34 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.57657783 |
| 35 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.56935562 |
| 36 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.55514074 |
| 37 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.54482506 |
| 38 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.54295097 |
| 39 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.52912295 |
| 40 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.52729111 |
| 41 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.52579581 |
| 42 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.49313371 |
| 43 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.46305609 |
| 44 | FUS_26573619_Chip-Seq_HEK293_Human | 1.43258011 |
| 45 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.37533266 |
| 46 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.37351825 |
| 47 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.37026806 |
| 48 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.36846354 |
| 49 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.36583351 |
| 50 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.36188169 |
| 51 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.35317626 |
| 52 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.30461735 |
| 53 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.30001173 |
| 54 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.29990036 |
| 55 | EWS_26573619_Chip-Seq_HEK293_Human | 1.29575917 |
| 56 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.29551353 |
| 57 | VDR_22108803_ChIP-Seq_LS180_Human | 1.26494183 |
| 58 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.22578059 |
| 59 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.22576097 |
| 60 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.21312240 |
| 61 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.19641336 |
| 62 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.18602266 |
| 63 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.18004313 |
| 64 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.17114928 |
| 65 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.15640146 |
| 66 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.14674957 |
| 67 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.13974988 |
| 68 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.11832441 |
| 69 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.10088503 |
| 70 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.09946832 |
| 71 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.08686940 |
| 72 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.08319751 |
| 73 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.03856334 |
| 74 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.02480962 |
| 75 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.01778899 |
| 76 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.01038167 |
| 77 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.98758257 |
| 78 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.98292364 |
| 79 | P300_19829295_ChIP-Seq_ESCs_Human | 0.97362695 |
| 80 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.95645961 |
| 81 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.93764653 |
| 82 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.92709035 |
| 83 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.92052059 |
| 84 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.91369068 |
| 85 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.89747488 |
| 86 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.89262548 |
| 87 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.88635655 |
| 88 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.88233015 |
| 89 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.87917626 |
| 90 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.86847029 |
| 91 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.86724115 |
| 92 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.84300175 |
| 93 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.83379689 |
| 94 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.83320576 |
| 95 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.82971804 |
| 96 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.81580329 |
| 97 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.80859014 |
| 98 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.80416036 |
| 99 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.79032696 |
| 100 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.77556302 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002102_abnormal_ear_morphology | 4.48206697 |
| 2 | MP0002163_abnormal_gland_morphology | 3.90044731 |
| 3 | MP0006072_abnormal_retinal_apoptosis | 3.82308315 |
| 4 | MP0010030_abnormal_orbit_morphology | 3.60614641 |
| 5 | MP0003122_maternal_imprinting | 3.11514252 |
| 6 | MP0005645_abnormal_hypothalamus_physiol | 3.06125471 |
| 7 | MP0006292_abnormal_olfactory_placode | 3.05011347 |
| 8 | MP0001529_abnormal_vocalization | 2.86133181 |
| 9 | MP0005394_taste/olfaction_phenotype | 2.71992744 |
| 10 | MP0005499_abnormal_olfactory_system | 2.71992744 |
| 11 | MP0003880_abnormal_central_pattern | 2.56389815 |
| 12 | MP0008789_abnormal_olfactory_epithelium | 2.55489818 |
| 13 | MP0005379_endocrine/exocrine_gland_phen | 2.53670560 |
| 14 | MP0005253_abnormal_eye_physiology | 2.41279534 |
| 15 | MP0006276_abnormal_autonomic_nervous | 2.37197743 |
| 16 | MP0003011_delayed_dark_adaptation | 2.15664317 |
| 17 | MP0002822_catalepsy | 2.15326298 |
| 18 | MP0000049_abnormal_middle_ear | 2.05332255 |
| 19 | MP0000778_abnormal_nervous_system | 1.93491454 |
| 20 | MP0004133_heterotaxia | 1.91208934 |
| 21 | MP0002653_abnormal_ependyma_morphology | 1.86398809 |
| 22 | MP0002938_white_spotting | 1.78181319 |
| 23 | MP0003121_genomic_imprinting | 1.72918779 |
| 24 | MP0000750_abnormal_muscle_regeneration | 1.62911629 |
| 25 | MP0002282_abnormal_trachea_morphology | 1.60405110 |
| 26 | MP0006054_spinal_hemorrhage | 1.58944917 |
| 27 | MP0002638_abnormal_pupillary_reflex | 1.57915620 |
| 28 | MP0009046_muscle_twitch | 1.53113473 |
| 29 | MP0003890_abnormal_embryonic-extraembry | 1.50473958 |
| 30 | MP0003787_abnormal_imprinting | 1.44758472 |
| 31 | MP0000569_abnormal_digit_pigmentation | 1.44017968 |
| 32 | MP0005551_abnormal_eye_electrophysiolog | 1.43698613 |
| 33 | MP0008058_abnormal_DNA_repair | 1.40172606 |
| 34 | MP0001293_anophthalmia | 1.33939066 |
| 35 | MP0003937_abnormal_limbs/digits/tail_de | 1.32281145 |
| 36 | MP0005391_vision/eye_phenotype | 1.30780947 |
| 37 | MP0002752_abnormal_somatic_nervous | 1.28346515 |
| 38 | MP0001984_abnormal_olfaction | 1.24485862 |
| 39 | MP0005377_hearing/vestibular/ear_phenot | 1.23933780 |
| 40 | MP0003878_abnormal_ear_physiology | 1.23933780 |
| 41 | MP0008877_abnormal_DNA_methylation | 1.22563937 |
| 42 | MP0002557_abnormal_social/conspecific_i | 1.19755233 |
| 43 | MP0000631_abnormal_neuroendocrine_gland | 1.19394214 |
| 44 | MP0002928_abnormal_bile_duct | 1.18749124 |
| 45 | MP0003567_abnormal_fetal_cardiomyocyte | 1.17560294 |
| 46 | MP0003718_maternal_effect | 1.16937148 |
| 47 | MP0002233_abnormal_nose_morphology | 1.16259498 |
| 48 | MP0000955_abnormal_spinal_cord | 1.15599031 |
| 49 | MP0001986_abnormal_taste_sensitivity | 1.14709664 |
| 50 | MP0002751_abnormal_autonomic_nervous | 1.12656811 |
| 51 | MP0002736_abnormal_nociception_after | 1.12556355 |
| 52 | MP0005423_abnormal_somatic_nervous | 1.11188960 |
| 53 | MP0008875_abnormal_xenobiotic_pharmacok | 1.10710190 |
| 54 | MP0002160_abnormal_reproductive_system | 1.07049956 |
| 55 | MP0008569_lethality_at_weaning | 1.06594348 |
| 56 | MP0000026_abnormal_inner_ear | 1.03849292 |
| 57 | MP0002111_abnormal_tail_morphology | 1.01911527 |
| 58 | MP0005195_abnormal_posterior_eye | 1.00430815 |
| 59 | MP0001324_abnormal_eye_pigmentation | 1.00393617 |
| 60 | MP0002735_abnormal_chemical_nociception | 0.99812591 |
| 61 | MP0002184_abnormal_innervation | 0.99141954 |
| 62 | MP0004924_abnormal_behavior | 0.96733598 |
| 63 | MP0005386_behavior/neurological_phenoty | 0.96733598 |
| 64 | MP0008260_abnormal_autophagy | 0.96142245 |
| 65 | MP0005084_abnormal_gallbladder_morpholo | 0.94985639 |
| 66 | MP0004957_abnormal_blastocyst_morpholog | 0.92578226 |
| 67 | MP0002090_abnormal_vision | 0.90151156 |
| 68 | MP0009379_abnormal_foot_pigmentation | 0.90083027 |
| 69 | MP0001485_abnormal_pinna_reflex | 0.89403800 |
| 70 | MP0001756_abnormal_urination | 0.88782976 |
| 71 | MP0002734_abnormal_mechanical_nocicepti | 0.87821106 |
| 72 | MP0006036_abnormal_mitochondrial_physio | 0.87126489 |
| 73 | MP0003186_abnormal_redox_activity | 0.86992855 |
| 74 | MP0002882_abnormal_neuron_morphology | 0.83952459 |
| 75 | MP0004811_abnormal_neuron_physiology | 0.82388758 |
| 76 | MP0001968_abnormal_touch/_nociception | 0.81804041 |
| 77 | MP0004270_analgesia | 0.81012668 |
| 78 | MP0003861_abnormal_nervous_system | 0.80924169 |
| 79 | MP0001286_abnormal_eye_development | 0.79914952 |
| 80 | MP0002210_abnormal_sex_determination | 0.79647281 |
| 81 | MP0003755_abnormal_palate_morphology | 0.78121606 |
| 82 | MP0008932_abnormal_embryonic_tissue | 0.77221824 |
| 83 | MP0002116_abnormal_craniofacial_bone | 0.75685712 |
| 84 | MP0002234_abnormal_pharynx_morphology | 0.75087955 |
| 85 | MP0005174_abnormal_tail_pigmentation | 0.74585201 |
| 86 | MP0002272_abnormal_nervous_system | 0.74004695 |
| 87 | MP0001905_abnormal_dopamine_level | 0.73087954 |
| 88 | MP0006035_abnormal_mitochondrial_morpho | 0.70382838 |
| 89 | MP0003385_abnormal_body_wall | 0.69983109 |
| 90 | MP0005085_abnormal_gallbladder_physiolo | 0.68699520 |
| 91 | MP0003635_abnormal_synaptic_transmissio | 0.68522260 |
| 92 | MP0000358_abnormal_cell_content/ | 0.67781621 |
| 93 | MP0003806_abnormal_nucleotide_metabolis | 0.67734558 |
| 94 | MP0002152_abnormal_brain_morphology | 0.67386907 |
| 95 | MP0002066_abnormal_motor_capabilities/c | 0.66914466 |
| 96 | MP0001963_abnormal_hearing_physiology | 0.65839973 |
| 97 | MP0003137_abnormal_impulse_conducting | 0.65677812 |
| 98 | MP0002084_abnormal_developmental_patter | 0.65206941 |
| 99 | MP0002063_abnormal_learning/memory/cond | 0.64783327 |
| 100 | MP0004134_abnormal_chest_morphology | 0.63900492 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased hepatocellular lipid droplets (HP:0006565) | 4.69593652 |
| 2 | Abnormality of midbrain morphology (HP:0002418) | 4.39118537 |
| 3 | Molar tooth sign on MRI (HP:0002419) | 4.39118537 |
| 4 | Colon cancer (HP:0003003) | 4.15755250 |
| 5 | Lipid accumulation in hepatocytes (HP:0006561) | 3.88622776 |
| 6 | Rhabdomyosarcoma (HP:0002859) | 3.60341133 |
| 7 | Renal Fanconi syndrome (HP:0001994) | 3.60093630 |
| 8 | Acute necrotizing encephalopathy (HP:0006965) | 3.51918252 |
| 9 | Occipital encephalocele (HP:0002085) | 3.50018059 |
| 10 | Mitochondrial inheritance (HP:0001427) | 3.48983420 |
| 11 | Rib fusion (HP:0000902) | 3.40515403 |
| 12 | Microvesicular hepatic steatosis (HP:0001414) | 3.38810413 |
| 13 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.32804840 |
| 14 | Acute encephalopathy (HP:0006846) | 3.22706512 |
| 15 | Polyphagia (HP:0002591) | 3.22621772 |
| 16 | Amelogenesis imperfecta (HP:0000705) | 3.21257616 |
| 17 | Long foot (HP:0001833) | 3.13622351 |
| 18 | Increased CSF lactate (HP:0002490) | 3.12391562 |
| 19 | Hyperglycinemia (HP:0002154) | 2.98853688 |
| 20 | Exertional dyspnea (HP:0002875) | 2.87985391 |
| 21 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.87404612 |
| 22 | True hermaphroditism (HP:0010459) | 2.85477793 |
| 23 | Nephronophthisis (HP:0000090) | 2.83415543 |
| 24 | Chronic hepatic failure (HP:0100626) | 2.82655023 |
| 25 | Nephrogenic diabetes insipidus (HP:0009806) | 2.76221265 |
| 26 | Medial flaring of the eyebrow (HP:0010747) | 2.73473197 |
| 27 | Cerebral hypomyelination (HP:0006808) | 2.71127352 |
| 28 | Hepatocellular necrosis (HP:0001404) | 2.69369129 |
| 29 | Progressive macrocephaly (HP:0004481) | 2.68433347 |
| 30 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.64735269 |
| 31 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.64735269 |
| 32 | Ependymoma (HP:0002888) | 2.63638131 |
| 33 | Hyperglycinuria (HP:0003108) | 2.62929567 |
| 34 | Increased intramyocellular lipid droplets (HP:0012240) | 2.60788845 |
| 35 | Congenital primary aphakia (HP:0007707) | 2.58008245 |
| 36 | Retinal dysplasia (HP:0007973) | 2.57328570 |
| 37 | Thyroid-stimulating hormone excess (HP:0002925) | 2.57305821 |
| 38 | Neoplasm of striated muscle (HP:0009728) | 2.54377036 |
| 39 | Tubular atrophy (HP:0000092) | 2.53954591 |
| 40 | Supernumerary spleens (HP:0009799) | 2.53844112 |
| 41 | Increased serum lactate (HP:0002151) | 2.52994435 |
| 42 | Gait imbalance (HP:0002141) | 2.52824775 |
| 43 | Pancreatic cysts (HP:0001737) | 2.51650206 |
| 44 | Microretrognathia (HP:0000308) | 2.43494294 |
| 45 | Cerebral edema (HP:0002181) | 2.41431863 |
| 46 | Myokymia (HP:0002411) | 2.35065568 |
| 47 | Hepatic necrosis (HP:0002605) | 2.31722834 |
| 48 | Pancreatic fibrosis (HP:0100732) | 2.30009540 |
| 49 | Abnormality of glycine metabolism (HP:0010895) | 2.27918329 |
| 50 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.27918329 |
| 51 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.26265427 |
| 52 | Postaxial hand polydactyly (HP:0001162) | 2.24470079 |
| 53 | Upper limb muscle weakness (HP:0003484) | 2.23010661 |
| 54 | Respiratory difficulties (HP:0002880) | 2.20153191 |
| 55 | Agnosia (HP:0010524) | 2.19105658 |
| 56 | Abnormal biliary tract physiology (HP:0012439) | 2.18602534 |
| 57 | Bile duct proliferation (HP:0001408) | 2.18602534 |
| 58 | Abnormality of the astrocytes (HP:0100707) | 2.17327533 |
| 59 | Astrocytoma (HP:0009592) | 2.17327533 |
| 60 | Hyperphosphaturia (HP:0003109) | 2.16326876 |
| 61 | Postaxial foot polydactyly (HP:0001830) | 2.15964158 |
| 62 | Bifid tongue (HP:0010297) | 2.14399940 |
| 63 | Abnormality of renal resorption (HP:0011038) | 2.14340255 |
| 64 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.10935916 |
| 65 | Lactic acidosis (HP:0003128) | 2.04063205 |
| 66 | Exercise intolerance (HP:0003546) | 2.02567923 |
| 67 | Abnormality of urine glucose concentration (HP:0011016) | 2.00482544 |
| 68 | Glycosuria (HP:0003076) | 2.00482544 |
| 69 | Vaginal atresia (HP:0000148) | 1.99131153 |
| 70 | CNS hypomyelination (HP:0003429) | 1.97735055 |
| 71 | Abnormality of dental color (HP:0011073) | 1.96376847 |
| 72 | Septo-optic dysplasia (HP:0100842) | 1.96139201 |
| 73 | Broad foot (HP:0001769) | 1.95685912 |
| 74 | Epileptic encephalopathy (HP:0200134) | 1.93553162 |
| 75 | Pendular nystagmus (HP:0012043) | 1.91631904 |
| 76 | Abnormality of the renal medulla (HP:0100957) | 1.90396869 |
| 77 | Leukodystrophy (HP:0002415) | 1.87584738 |
| 78 | Cortical dysplasia (HP:0002539) | 1.87499676 |
| 79 | Optic disc pallor (HP:0000543) | 1.86554726 |
| 80 | Anencephaly (HP:0002323) | 1.85834554 |
| 81 | Abnormal ciliary motility (HP:0012262) | 1.85381235 |
| 82 | Genital tract atresia (HP:0001827) | 1.84996052 |
| 83 | Increased muscle lipid content (HP:0009058) | 1.84796676 |
| 84 | Abnormality of abdominal situs (HP:0011620) | 1.83255419 |
| 85 | Abdominal situs inversus (HP:0003363) | 1.83255419 |
| 86 | Narrow forehead (HP:0000341) | 1.79878815 |
| 87 | Inability to walk (HP:0002540) | 1.79769087 |
| 88 | Increased serum pyruvate (HP:0003542) | 1.77763534 |
| 89 | Exercise-induced muscle cramps (HP:0003710) | 1.77313758 |
| 90 | Glioma (HP:0009733) | 1.76880046 |
| 91 | Decreased muscle mass (HP:0003199) | 1.76126309 |
| 92 | Hand muscle atrophy (HP:0009130) | 1.75914356 |
| 93 | Anomalous pulmonary venous return (HP:0010772) | 1.74779236 |
| 94 | Failure to thrive in infancy (HP:0001531) | 1.73376094 |
| 95 | Poor coordination (HP:0002370) | 1.72274791 |
| 96 | Abnormality of serum amino acid levels (HP:0003112) | 1.72211837 |
| 97 | Generalized hypotonia (HP:0001290) | 1.70797293 |
| 98 | Reticulocytopenia (HP:0001896) | 1.70676275 |
| 99 | Oculomotor apraxia (HP:0000657) | 1.70188714 |
| 100 | Neonatal respiratory distress (HP:0002643) | 1.64378717 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 6.48338209 |
| 2 | CDK9 | 3.88557576 |
| 3 | BCKDK | 3.23812352 |
| 4 | STK16 | 3.18998454 |
| 5 | WNK3 | 2.98017036 |
| 6 | TRIM28 | 2.93300925 |
| 7 | EPHA4 | 2.43068379 |
| 8 | WNK1 | 2.39737960 |
| 9 | CDK19 | 2.38600245 |
| 10 | BMPR1B | 2.32976102 |
| 11 | MKNK1 | 2.26558334 |
| 12 | SRPK1 | 2.19845057 |
| 13 | NUAK1 | 2.05188442 |
| 14 | MKNK2 | 2.03930111 |
| 15 | MAPK15 | 2.01583788 |
| 16 | BCR | 1.96672959 |
| 17 | TNIK | 1.88838845 |
| 18 | DYRK3 | 1.66089888 |
| 19 | PBK | 1.58199987 |
| 20 | CSNK1G3 | 1.52235108 |
| 21 | CSNK1G1 | 1.45704049 |
| 22 | VRK2 | 1.43981832 |
| 23 | ZAK | 1.43659356 |
| 24 | EIF2AK3 | 1.37465970 |
| 25 | CSNK1A1L | 1.37179520 |
| 26 | TGFBR1 | 1.34696290 |
| 27 | ACVR1B | 1.32933843 |
| 28 | CASK | 1.32190530 |
| 29 | PLK4 | 1.31892593 |
| 30 | MAP3K4 | 1.31277531 |
| 31 | DYRK2 | 1.26564205 |
| 32 | CSNK1G2 | 1.23939354 |
| 33 | INSRR | 1.20070663 |
| 34 | GRK1 | 1.14626634 |
| 35 | PDK2 | 1.03554411 |
| 36 | OXSR1 | 1.02209937 |
| 37 | PLK2 | 0.99919512 |
| 38 | MAPK13 | 0.99696825 |
| 39 | TSSK6 | 0.96007187 |
| 40 | TLK1 | 0.95544069 |
| 41 | AKT2 | 0.95492292 |
| 42 | PLK3 | 0.93998048 |
| 43 | NME1 | 0.89274583 |
| 44 | TIE1 | 0.88440369 |
| 45 | NTRK2 | 0.88311069 |
| 46 | CDK8 | 0.83756755 |
| 47 | CDK3 | 0.77593759 |
| 48 | ADRBK2 | 0.76123730 |
| 49 | PLK1 | 0.72126810 |
| 50 | EPHB2 | 0.70025654 |
| 51 | DYRK1A | 0.68832978 |
| 52 | CAMK1D | 0.67567445 |
| 53 | TTK | 0.65410393 |
| 54 | CDK18 | 0.62530934 |
| 55 | MINK1 | 0.62406715 |
| 56 | CDK11A | 0.60232511 |
| 57 | CDK14 | 0.59264481 |
| 58 | ERBB4 | 0.58853925 |
| 59 | CDK15 | 0.57437897 |
| 60 | VRK1 | 0.54550285 |
| 61 | ILK | 0.53911860 |
| 62 | ATR | 0.52971868 |
| 63 | RPS6KA5 | 0.52712512 |
| 64 | EIF2AK1 | 0.51762854 |
| 65 | EPHA2 | 0.50486470 |
| 66 | CSNK1A1 | 0.48951692 |
| 67 | NEK2 | 0.48934050 |
| 68 | RPS6KA4 | 0.48010174 |
| 69 | MAP2K7 | 0.46726563 |
| 70 | PRKCG | 0.46034312 |
| 71 | PRKCE | 0.43954200 |
| 72 | CLK1 | 0.42129200 |
| 73 | KDR | 0.41794642 |
| 74 | LATS1 | 0.41705935 |
| 75 | AURKA | 0.41241054 |
| 76 | CAMK1 | 0.41196452 |
| 77 | ADRBK1 | 0.40857410 |
| 78 | DYRK1B | 0.38928250 |
| 79 | MUSK | 0.38401676 |
| 80 | CDC7 | 0.37701625 |
| 81 | TEC | 0.36842041 |
| 82 | PTK2B | 0.36657798 |
| 83 | CSNK1E | 0.35898337 |
| 84 | FLT3 | 0.34502036 |
| 85 | ATM | 0.33492478 |
| 86 | PRKG1 | 0.32024046 |
| 87 | CDK5 | 0.30438000 |
| 88 | ALK | 0.29937055 |
| 89 | PRKACA | 0.29516386 |
| 90 | NEK1 | 0.28855524 |
| 91 | CAMK2A | 0.28261960 |
| 92 | OBSCN | 0.28199342 |
| 93 | PAK3 | 0.27751389 |
| 94 | BUB1 | 0.27647803 |
| 95 | PRKCI | 0.26875058 |
| 96 | FGFR1 | 0.24405949 |
| 97 | CSNK2A1 | 0.24261427 |
| 98 | CSNK1D | 0.24242145 |
| 99 | CAMK4 | 0.23443493 |
| 100 | GRK5 | 0.23267348 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Protein export_Homo sapiens_hsa03060 | 4.48312049 |
| 2 | Sulfur relay system_Homo sapiens_hsa04122 | 3.92305327 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 3.23095662 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.99799600 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.86164653 |
| 6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.81574041 |
| 7 | Proteasome_Homo sapiens_hsa03050 | 2.55496467 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.21081956 |
| 9 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.15431720 |
| 10 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.14971346 |
| 11 | Huntingtons disease_Homo sapiens_hsa05016 | 2.14608143 |
| 12 | Basal transcription factors_Homo sapiens_hsa03022 | 2.11550782 |
| 13 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.86671775 |
| 14 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.80916184 |
| 15 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.77307699 |
| 16 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.72662598 |
| 17 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.72191728 |
| 18 | Alzheimers disease_Homo sapiens_hsa05010 | 1.70914381 |
| 19 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.67938879 |
| 20 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.67568471 |
| 21 | Base excision repair_Homo sapiens_hsa03410 | 1.53675875 |
| 22 | RNA transport_Homo sapiens_hsa03013 | 1.52504465 |
| 23 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.45364924 |
| 24 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.44747304 |
| 25 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.40174244 |
| 26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.34764436 |
| 27 | Peroxisome_Homo sapiens_hsa04146 | 1.29598596 |
| 28 | GABAergic synapse_Homo sapiens_hsa04727 | 1.25054779 |
| 29 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.24748640 |
| 30 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.21559043 |
| 31 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.20790928 |
| 32 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.20200280 |
| 33 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.19501641 |
| 34 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.16195351 |
| 35 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.14157018 |
| 36 | Spliceosome_Homo sapiens_hsa03040 | 1.12954749 |
| 37 | Mismatch repair_Homo sapiens_hsa03430 | 1.09982177 |
| 38 | RNA degradation_Homo sapiens_hsa03018 | 1.08961999 |
| 39 | Phototransduction_Homo sapiens_hsa04744 | 1.07560169 |
| 40 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.05762999 |
| 41 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.04042687 |
| 42 | Carbon metabolism_Homo sapiens_hsa01200 | 1.01817645 |
| 43 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.00913423 |
| 44 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.99985340 |
| 45 | Cocaine addiction_Homo sapiens_hsa05030 | 0.94416832 |
| 46 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.93251113 |
| 47 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.89770523 |
| 48 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.86100946 |
| 49 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.84776979 |
| 50 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.81405496 |
| 51 | Metabolic pathways_Homo sapiens_hsa01100 | 0.80667090 |
| 52 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.79365749 |
| 53 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.78669859 |
| 54 | Olfactory transduction_Homo sapiens_hsa04740 | 0.77876108 |
| 55 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.76286537 |
| 56 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.75542563 |
| 57 | Nicotine addiction_Homo sapiens_hsa05033 | 0.73572696 |
| 58 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.73235921 |
| 59 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.70403831 |
| 60 | Purine metabolism_Homo sapiens_hsa00230 | 0.70190428 |
| 61 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.69453383 |
| 62 | Morphine addiction_Homo sapiens_hsa05032 | 0.66980583 |
| 63 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.65605319 |
| 64 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.65371450 |
| 65 | Homologous recombination_Homo sapiens_hsa03440 | 0.64428918 |
| 66 | Taste transduction_Homo sapiens_hsa04742 | 0.59438038 |
| 67 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.56608647 |
| 68 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.56141042 |
| 69 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.55987867 |
| 70 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.53729575 |
| 71 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.51867233 |
| 72 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.51867028 |
| 73 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.51553651 |
| 74 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.51048094 |
| 75 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.48000334 |
| 76 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.46543998 |
| 77 | Retinol metabolism_Homo sapiens_hsa00830 | 0.45857002 |
| 78 | Insulin secretion_Homo sapiens_hsa04911 | 0.44922887 |
| 79 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.44441364 |
| 80 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.43716012 |
| 81 | Alcoholism_Homo sapiens_hsa05034 | 0.43562090 |
| 82 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.43015577 |
| 83 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.42609275 |
| 84 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.42160961 |
| 85 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.40468758 |
| 86 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.40202475 |
| 87 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.40152230 |
| 88 | Malaria_Homo sapiens_hsa05144 | 0.39815044 |
| 89 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.39763934 |
| 90 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.37797767 |
| 91 | Axon guidance_Homo sapiens_hsa04360 | 0.37500380 |
| 92 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.36358760 |
| 93 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.36065230 |
| 94 | Circadian entrainment_Homo sapiens_hsa04713 | 0.34642657 |
| 95 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.33867866 |
| 96 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.33661311 |
| 97 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.32885859 |
| 98 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.31867070 |
| 99 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.30496289 |
| 100 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.29584715 |

