TDRD9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1fusion of sperm to egg plasma membrane (GO:0007342)9.87806218
2regulation of meiosis I (GO:0060631)8.70197047
3male meiosis I (GO:0007141)8.07774635
4axonemal dynein complex assembly (GO:0070286)7.90280478
5sperm motility (GO:0030317)7.81271995
6chromosome organization involved in meiosis (GO:0070192)7.69785964
7sperm-egg recognition (GO:0035036)7.62235207
8multicellular organism reproduction (GO:0032504)7.58396626
9plasma membrane fusion (GO:0045026)7.41734515
10acrosome assembly (GO:0001675)7.39748239
11spermatid development (GO:0007286)7.29663188
12binding of sperm to zona pellucida (GO:0007339)7.19521943
13* meiotic nuclear division (GO:0007126)7.19096507
14cell-cell recognition (GO:0009988)6.79424928
15epithelial cilium movement (GO:0003351)6.79401372
16meiosis I (GO:0007127)6.75576574
17motile cilium assembly (GO:0044458)6.53056072
18epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.38786100
19resolution of meiotic recombination intermediates (GO:0000712)6.25069903
20* gene silencing by RNA (GO:0031047)6.20140680
21cilium movement (GO:0003341)6.11279231
22acrosome reaction (GO:0007340)6.08143335
23meiotic cell cycle (GO:0051321)6.08049986
24reproduction (GO:0000003)6.04624721
25meiotic chromosome segregation (GO:0045132)6.02854487
26cell wall macromolecule metabolic process (GO:0044036)5.80163351
27cell wall macromolecule catabolic process (GO:0016998)5.80163351
28histone H3-K9 demethylation (GO:0033169)5.79504822
29germ cell development (GO:0007281)5.27896540
30regulation of cilium movement (GO:0003352)5.12802544
31negative regulation of inclusion body assembly (GO:0090084)5.10655475
32single fertilization (GO:0007338)5.07509077
33meiotic cell cycle process (GO:1903046)5.04024028
34* fertilization (GO:0009566)5.02269943
35* spermatogenesis (GO:0007283)4.95081369
36* DNA methylation (GO:0006306)4.94671110
37* DNA alkylation (GO:0006305)4.94671110
38* male gamete generation (GO:0048232)4.93858004
39nuclear pore complex assembly (GO:0051292)4.89217431
40cellular process involved in reproduction in multicellular organism (GO:0022412)4.85662715
41histone H3-K36 demethylation (GO:0070544)4.75611097
42* gamete generation (GO:0007276)4.59356389
43nuclear pore organization (GO:0006999)4.58459012
44monoubiquitinated protein deubiquitination (GO:0035520)4.33055958
45* gene silencing (GO:0016458)4.31272176
46synapsis (GO:0007129)4.27315430
47oogenesis (GO:0048477)4.13579001
48seminiferous tubule development (GO:0072520)4.10164693
49genitalia morphogenesis (GO:0035112)4.08446623
50ventricular system development (GO:0021591)4.07996245
51regulation of meiotic cell cycle (GO:0051445)4.07288402
52microtubule depolymerization (GO:0007019)3.93905296
53sperm capacitation (GO:0048240)3.90330498
54regulation of inclusion body assembly (GO:0090083)3.85578269
55sister chromatid cohesion (GO:0007062)3.74018735
56pore complex assembly (GO:0046931)3.72638411
57* DNA methylation or demethylation (GO:0044728)3.71285194
58positive regulation of meiosis (GO:0045836)3.68612743
59sex differentiation (GO:0007548)3.63461196
60* multicellular organismal reproductive process (GO:0048609)3.59393538
61regulation of protein polyubiquitination (GO:1902914)3.58887609
62mitotic sister chromatid cohesion (GO:0007064)3.58720034
63positive regulation of meiotic cell cycle (GO:0051446)3.55938928
64regulation of histone H3-K9 methylation (GO:0051570)3.52039098
65regulation of DNA endoreduplication (GO:0032875)3.51406699
66positive regulation of response to oxidative stress (GO:1902884)3.51401039
67positive regulation of cellular response to oxidative stress (GO:1900409)3.51401039
68regulation of centriole replication (GO:0046599)3.47962521
69protein localization to cilium (GO:0061512)3.47706379
70regulation of microtubule-based movement (GO:0060632)3.35889788
71negative regulation of meiosis (GO:0045835)3.35161885
72negative regulation of DNA repair (GO:0045738)3.31946609
73histone lysine demethylation (GO:0070076)3.31450410
74intraciliary transport (GO:0042073)3.31282926
75histone demethylation (GO:0016577)3.24307309
76female gamete generation (GO:0007292)3.19669534
77microtubule severing (GO:0051013)3.15765504
78DNA biosynthetic process (GO:0071897)3.15070203
79cell recognition (GO:0008037)3.12459991
80DNA packaging (GO:0006323)3.07164726
81centriole replication (GO:0007099)3.02636720
82reciprocal meiotic recombination (GO:0007131)3.02539619
83reciprocal DNA recombination (GO:0035825)3.02539619
84chaperone-mediated protein complex assembly (GO:0051131)3.01321663
85negative regulation of organelle assembly (GO:1902116)3.01093010
86nucleus organization (GO:0006997)3.00116407
87* DNA modification (GO:0006304)2.98796072
88histone H3-K9 methylation (GO:0051567)2.98658773
89protein demethylation (GO:0006482)2.97549805
90protein dealkylation (GO:0008214)2.97549805
91oocyte development (GO:0048599)2.97207302
92chromosome organization (GO:0051276)2.94616321
93heterochromatin organization (GO:0070828)2.94358383
94regulation of chromatin binding (GO:0035561)2.92817002
95translesion synthesis (GO:0019985)2.92312277
96histone exchange (GO:0043486)2.87482662
97interkinetic nuclear migration (GO:0022027)2.85863836
98regulation of meiosis (GO:0040020)2.82583000
99chromosome condensation (GO:0030261)2.82327256
100histone H2A acetylation (GO:0043968)2.82229204
101left/right pattern formation (GO:0060972)2.81378718
102* multicellular organismal development (GO:0007275)2.80558393
103DNA replication-dependent nucleosome organization (GO:0034723)2.79389814
104DNA replication-dependent nucleosome assembly (GO:0006335)2.79389814
105regulation of RNA export from nucleus (GO:0046831)2.79212065
106centriole assembly (GO:0098534)2.78436689
107mitotic chromosome condensation (GO:0007076)2.77513503
108oocyte maturation (GO:0001556)2.76359915
109axoneme assembly (GO:0035082)2.75860749
110protein targeting to Golgi (GO:0000042)2.75065081
111protein localization to chromosome (GO:0034502)2.74237533
112regulation of spindle checkpoint (GO:0090231)2.73109211
113histone H4-K12 acetylation (GO:0043983)2.72901680
114regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.71222563
115establishment of protein localization to Golgi (GO:0072600)2.68288762
116reproductive system development (GO:0061458)2.66578126
117Golgi to endosome transport (GO:0006895)2.62701867
118histone H4-K16 acetylation (GO:0043984)2.60161736
119response to peptidoglycan (GO:0032494)2.60042418
120attachment of spindle microtubules to kinetochore (GO:0008608)2.59901011
121retrograde transport, vesicle recycling within Golgi (GO:0000301)2.59221334
122negative regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045736)2.57000671
123negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518)2.51975754
124macroautophagy (GO:0016236)2.48683559
125* nuclear division (GO:0000280)2.38066187
126embryonic body morphogenesis (GO:0010172)2.32706396
127poly(A)+ mRNA export from nucleus (GO:0016973)2.28669411
128energy homeostasis (GO:0097009)2.27913265
129negative regulation of NF-kappaB import into nucleus (GO:0042347)2.25206193
130* organelle fission (GO:0048285)2.23701096
131positive regulation of histone methylation (GO:0031062)2.18518815
132positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.16606788
133intra-Golgi vesicle-mediated transport (GO:0006891)2.14612835
134neutrophil activation involved in immune response (GO:0002283)2.13615172
135protein K11-linked deubiquitination (GO:0035871)2.13068945
136brain morphogenesis (GO:0048854)2.13052781
137phosphorylated carbohydrate dephosphorylation (GO:0046838)2.11551952
138* piRNA metabolic process (GO:0034587)15.5324172
139cilium or flagellum-dependent cell motility (GO:0001539)11.8956010
140* male meiosis (GO:0007140)11.2493894
141synaptonemal complex organization (GO:0070193)11.2438657
142* DNA methylation involved in gamete generation (GO:0043046)11.2143777
143synaptonemal complex assembly (GO:0007130)11.1179338
144DNA synthesis involved in DNA repair (GO:0000731)10.8684712

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.79026768
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.69123375
3IGF1R_20145208_ChIP-Seq_DFB_Human3.53025374
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.09578920
5* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.96125003
6POU3F2_20337985_ChIP-ChIP_501MEL_Human2.49925521
7GATA1_26923725_Chip-Seq_HPCs_Mouse2.49163849
8FOXM1_23109430_ChIP-Seq_U2OS_Human2.40453164
9IRF8_21731497_ChIP-ChIP_J774_Mouse2.31765835
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.30753121
11ER_23166858_ChIP-Seq_MCF-7_Human2.14894209
12MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse12.7785348
13SALL1_21062744_ChIP-ChIP_HESCs_Human1.96732736
14IRF8_27001747_Chip-Seq_BMDM_Mouse1.94445519
15FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.93187944
16CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.92977650
17EGR1_19374776_ChIP-ChIP_THP-1_Human1.91700981
18MYB_21317192_ChIP-Seq_ERMYB_Mouse1.86376388
19ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.85995489
20PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.82335255
21PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.81375236
22ELK4_26923725_Chip-Seq_MESODERM_Mouse1.80238461
23PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.79081276
24FLI1_27457419_Chip-Seq_LIVER_Mouse1.78225614
25SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.77751683
26GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.76792872
27ZNF274_21170338_ChIP-Seq_K562_Hela1.70406776
28TFEB_21752829_ChIP-Seq_HELA_Human1.65394877
29* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.65070952
30Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.63281609
31MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.62445048
32WDR5_24793694_ChIP-Seq_LNCAP_Human1.59171051
33TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.58879730
34KAP1_22055183_ChIP-Seq_ESCs_Mouse1.56175781
35FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.54938330
36FUS_26573619_Chip-Seq_HEK293_Human1.54846907
37PCGF2_27294783_Chip-Seq_ESCs_Mouse1.52633447
38IRF8_22096565_ChIP-ChIP_GC-B_Human1.52174483
39TAF15_26573619_Chip-Seq_HEK293_Human1.51859223
40FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.51828968
41AR_21909140_ChIP-Seq_LNCAP_Human1.51436882
42E2F7_22180533_ChIP-Seq_HELA_Human1.49917341
43STAT3_23295773_ChIP-Seq_U87_Human1.48829203
44KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.48262724
45FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.45599269
46RUNX1_26923725_Chip-Seq_HPCs_Mouse1.43890323
47RUNX2_22187159_ChIP-Seq_PCA_Human1.38017242
48FOXA1_21572438_ChIP-Seq_LNCaP_Human1.37932175
49E2F4_17652178_ChIP-ChIP_JURKAT_Human1.37511817
50PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.36942314
51NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.36330659
52STAT1_17558387_ChIP-Seq_HELA_Human1.34574763
53NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.34495627
54RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.33210703
55UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.33044010
56BMI1_23680149_ChIP-Seq_NPCS_Mouse1.32552809
57TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human1.32478811
58MYCN_18555785_ChIP-Seq_MESCs_Mouse1.31834254
59SPI1_23547873_ChIP-Seq_NB4_Human1.31040747
60SMAD_19615063_ChIP-ChIP_OVARY_Human1.29626989
61TP53_22573176_ChIP-Seq_HFKS_Human1.29048256
62VDR_24787735_ChIP-Seq_THP-1_Human1.28858221
63MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.27882430
64FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.27325573
65RBPJ_22232070_ChIP-Seq_NCS_Mouse1.25301775
66SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.24892764
67SMAD4_21741376_ChIP-Seq_EPCs_Human1.22992642
68RNF2_27304074_Chip-Seq_NSC_Mouse1.22400242
69GATA3_26560356_Chip-Seq_TH2_Human1.22375278
70TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.21507439
71CTBP2_25329375_ChIP-Seq_LNCAP_Human1.21490600
72EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.21451533
73AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.21224118
74NANOG_18555785_Chip-Seq_ESCs_Mouse1.18830517
75RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.18470460
76AR_25329375_ChIP-Seq_VCAP_Human1.18170835
77GATA3_27048872_Chip-Seq_THYMUS_Human1.17136719
78PRDM14_20953172_ChIP-Seq_ESCs_Human1.17044696
79CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.17014066
80SMAD4_21799915_ChIP-Seq_A2780_Human1.16160473
81KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.16089801
82GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.15796642
83TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.15427937
84NFE2_27457419_Chip-Seq_LIVER_Mouse1.09582307
85STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.09351602
86MYB_26560356_Chip-Seq_TH2_Human1.08621351
87GATA3_21867929_ChIP-Seq_TH1_Mouse1.05812180
88FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.05256494
89CTBP1_25329375_ChIP-Seq_LNCAP_Human1.05059078
90ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.04850923
91E2F1_18555785_Chip-Seq_ESCs_Mouse1.03225434
92PCGF2_27294783_Chip-Seq_NPCs_Mouse1.02723750
93SOX2_22085726_ChIP-Seq_NPCs_Mouse1.02139375
94MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02046592
95FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01907760
96STAT3_18555785_Chip-Seq_ESCs_Mouse1.01643503
97* OCT4_19829295_ChIP-Seq_ESCs_Human1.00695891
98CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.00411589
99TP63_23658742_ChIP-Seq_EP156T_Human0.99745398
100P300_19829295_ChIP-Seq_ESCs_Human0.97682317
101CMYC_18555785_Chip-Seq_ESCs_Mouse0.96954033
102EZH2_27294783_Chip-Seq_NPCs_Mouse0.96309046
103RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.95810849
104DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.95519336
105FOXM1_26456572_ChIP-Seq_MCF-7_Human0.95256241
106P300_18555785_Chip-Seq_ESCs_Mouse0.95120410
107TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.94984095
108BCAT_22108803_ChIP-Seq_LS180_Human0.94623559
109PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.93357241
110* GATA3_21867929_ChIP-Seq_CD8_Mouse0.93153891
111RUNX1_22412390_ChIP-Seq_EML_Mouse0.93024936
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92829043
113POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.92829043
114SUZ12_27294783_Chip-Seq_NPCs_Mouse0.92525220
115CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91929289
116VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.91854766
117SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.91652356
118P53_21459846_ChIP-Seq_SAOS-2_Human0.90346438
119ZFP57_27257070_Chip-Seq_ESCs_Mouse0.89931968
120RUNX1_27457419_Chip-Seq_LIVER_Mouse0.89726346
121NFYB_21822215_ChIP-Seq_K562_Human0.89195041
122TCF4_22108803_ChIP-Seq_LS180_Human0.88943152
123PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.88881963
124SALL4_22934838_ChIP-ChIP_CD34+_Human0.88708545
125TBL1_22424771_ChIP-Seq_293T_Human0.88578411
126CBP_20019798_ChIP-Seq_JUKART_Human0.87831711
127IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.87831711
128TAL1_26923725_Chip-Seq_HPCs_Mouse0.87159274
129SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.86892920
130SOX2_21211035_ChIP-Seq_LN229_Human0.86711625
131FLI1_21867929_ChIP-Seq_CD8_Mouse0.86547466
132GF1_26923725_Chip-Seq_HPCs_Mouse0.86245631
133GATA3_26560356_Chip-Seq_TH1_Human0.86109822
134LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.84828352
135TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.84766424
136ETV1_20927104_ChIP-Seq_GIST48_Human0.82988921
137MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.82810900
138* TCF4_23295773_ChIP-Seq_U87_Human0.81287941
139SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.80645817
140CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.79407303
141CDX2_22108803_ChIP-Seq_LS180_Human0.79095380
142RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.79079517
143CBX2_27304074_Chip-Seq_ESCs_Mouse0.78980850
144SPI1_26923725_Chip-Seq_HPCs_Mouse0.77912856
145BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human0.77352040
146EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.77272171
147KDM5A_27292631_Chip-Seq_BREAST_Human0.76326293
148STAT3_18555785_ChIP-Seq_MESCs_Mouse0.75688533
149FLI1_21867929_ChIP-Seq_TH2_Mouse0.75580047
150CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.75237446
151PKCTHETA_26484144_Chip-Seq_BREAST_Human0.75061227
152RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.75009693
153LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.74806814
154* YY1_22570637_ChIP-Seq_MALME-3M_Human0.74698037
155GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.74562369
156E2F1_20622854_ChIP-Seq_HELA_Human0.74453613
157ETS1_22383799_ChIP-Seq_G1ME_Mouse0.74339762
158TET1_21490601_ChIP-Seq_MESCs_Mouse0.74238605
159EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.70840552
160GF1B_26923725_Chip-Seq_HPCs_Mouse0.70707061
161KDM2B_26808549_Chip-Seq_REH_Human0.70470280
162NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.70455034
163ERG_20517297_ChIP-Seq_VCAP_Human0.70274465

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization9.40936114
2* MP0008877_abnormal_DNA_methylation8.14219065
3* MP0001929_abnormal_gametogenesis5.25984154
4* MP0003698_abnormal_male_reproductive5.00443494
5* MP0002210_abnormal_sex_determination4.63899810
6MP0008995_early_reproductive_senescence4.20883419
7* MP0001145_abnormal_male_reproductive3.78673008
8MP0008057_abnormal_DNA_replication3.39985961
9* MP0000653_abnormal_sex_gland3.38704044
10MP0002653_abnormal_ependyma_morphology3.13505657
11* MP0002161_abnormal_fertility/fecundity2.87707545
12MP0003786_premature_aging2.81544864
13MP0000015_abnormal_ear_pigmentation2.79864939
14MP0010094_abnormal_chromosome_stability2.59185233
15MP0005174_abnormal_tail_pigmentation2.29382284
16MP0008058_abnormal_DNA_repair2.29328175
17MP0005058_abnormal_lysosome_morphology2.28537796
18MP0003646_muscle_fatigue2.26913943
19MP0008260_abnormal_autophagy2.26570385
20MP0003172_abnormal_lysosome_physiology2.23104098
21MP0005623_abnormal_meninges_morphology2.21647484
22MP0008004_abnormal_stomach_pH2.16905802
23MP0000383_abnormal_hair_follicle2.06508816
24MP0002160_abnormal_reproductive_system1.96429123
25MP0010678_abnormal_skin_adnexa1.92115627
26MP0003111_abnormal_nucleus_morphology1.89858929
27MP0003878_abnormal_ear_physiology1.86664868
28MP0005377_hearing/vestibular/ear_phenot1.86664868
29MP0003724_increased_susceptibility_to1.78132553
30MP0008007_abnormal_cellular_replicative1.77539660
31MP0003183_abnormal_peptide_metabolism1.72689231
32MP0005310_abnormal_salivary_gland1.68420928
33MP0003077_abnormal_cell_cycle1.53301726
34MP0000678_abnormal_parathyroid_gland1.44160038
35MP0004233_abnormal_muscle_weight1.42479148
36MP0010234_abnormal_vibrissa_follicle1.38013131
37MP0010307_abnormal_tumor_latency1.37080191
38MP0009278_abnormal_bone_marrow1.34817265
39MP0005075_abnormal_melanosome_morpholog1.32432580
40MP0001835_abnormal_antigen_presentation1.31783616
41MP0002095_abnormal_skin_pigmentation1.28886149
42MP0003693_abnormal_embryo_hatching1.28212282
43MP0005647_abnormal_sex_gland1.28096590
44MP0003656_abnormal_erythrocyte_physiolo1.22393714
45MP0001730_embryonic_growth_arrest1.21904478
46MP0004808_abnormal_hematopoietic_stem1.21078319
47MP0002419_abnormal_innate_immunity1.20637800
48MP0005409_darkened_coat_color1.18881152
49MP0004957_abnormal_blastocyst_morpholog1.17827475
50MP0006082_CNS_inflammation1.15713569
51MP0001661_extended_life_span1.11557504
52MP0005389_reproductive_system_phenotype1.11246036
53MP0001119_abnormal_female_reproductive1.10483523
54MP0003195_calcinosis1.09408501
55MP0000013_abnormal_adipose_tissue1.08426803
56MP0003699_abnormal_female_reproductive1.08017286
57MP0005397_hematopoietic_system_phenotyp1.05505735
58MP0001545_abnormal_hematopoietic_system1.05505735
59MP0003718_maternal_effect1.04526508
60MP0000569_abnormal_digit_pigmentation1.02178432
61MP0000371_diluted_coat_color1.01449819
62MP0003943_abnormal_hepatobiliary_system0.98199608
63MP0006035_abnormal_mitochondrial_morpho0.96720359
64MP0002282_abnormal_trachea_morphology0.95720037
65MP0005464_abnormal_platelet_physiology0.94723485
66MP0003787_abnormal_imprinting0.93179642
67MP0005451_abnormal_body_composition0.87060092
68MP0002102_abnormal_ear_morphology0.84472331
69MP0001800_abnormal_humoral_immune0.84075531
70MP0002723_abnormal_immune_serum0.82996704
71MP0003123_paternal_imprinting0.80839390
72MP0005670_abnormal_white_adipose0.80299123
73MP0009785_altered_susceptibility_to0.80054683
74MP0006036_abnormal_mitochondrial_physio0.77280630
75MP0003436_decreased_susceptibility_to0.76716960
76MP0001672_abnormal_embryogenesis/_devel0.76332159
77MP0005380_embryogenesis_phenotype0.76332159
78MP0002084_abnormal_developmental_patter0.76204531
79MP0002420_abnormal_adaptive_immunity0.75635674
80MP0003115_abnormal_respiratory_system0.75105694
81MP0005000_abnormal_immune_tolerance0.73663918
82MP0001501_abnormal_sleep_pattern0.73588750
83MP0000427_abnormal_hair_cycle0.72322430
84MP0001727_abnormal_embryo_implantation0.72316178
85MP0004134_abnormal_chest_morphology0.71911660
86MP0001819_abnormal_immune_cell0.71291389
87MP0008932_abnormal_embryonic_tissue0.70305719
88MP0002452_abnormal_antigen_presenting0.69866155
89MP0001764_abnormal_homeostasis0.68195373
90MP0002148_abnormal_hypersensitivity_rea0.67828220
91MP0001324_abnormal_eye_pigmentation0.67699646
92MP0000703_abnormal_thymus_morphology0.67010484
93MP0002928_abnormal_bile_duct0.66491713
94MP0003828_pulmonary_edema0.66360405
95MP0001697_abnormal_embryo_size0.65469016
96MP0003984_embryonic_growth_retardation0.65287255
97MP0002396_abnormal_hematopoietic_system0.65147993
98MP0000350_abnormal_cell_proliferation0.64889257
99MP0003121_genomic_imprinting0.64459770
100MP0004484_altered_response_of0.63392682
101MP0004381_abnormal_hair_follicle0.63059061
102MP0002085_abnormal_embryonic_tissue0.62827498
103MP0000313_abnormal_cell_death0.61171450
104MP0004197_abnormal_fetal_growth/weight/0.61020072
105MP0002088_abnormal_embryonic_growth/wei0.60583045
106MP0005025_abnormal_response_to0.60024108
107MP0005076_abnormal_cell_differentiation0.59835179
108MP0000685_abnormal_immune_system0.59647302
109MP0003453_abnormal_keratinocyte_physiol0.59516673
110MP0003011_delayed_dark_adaptation0.59190378
111MP0003191_abnormal_cellular_cholesterol0.58752499
112MP0002075_abnormal_coat/hair_pigmentati0.58667036
113MP0002405_respiratory_system_inflammati0.58442495
114MP0002080_prenatal_lethality0.58385885
115MP0003879_abnormal_hair_cell0.58119830
116MP0002693_abnormal_pancreas_physiology0.57350057
117MP0003936_abnormal_reproductive_system0.56810575
118MP0002398_abnormal_bone_marrow0.56159339
119MP0003763_abnormal_thymus_physiology0.56122315
120MP0002229_neurodegeneration0.55267550
121MP0010352_gastrointestinal_tract_polyps0.55206048
122MP0005671_abnormal_response_to0.55174962
123MP0002722_abnormal_immune_system0.55045000
124MP0001915_intracranial_hemorrhage0.54685482
125MP0000358_abnormal_cell_content/0.54681993
126MP0005551_abnormal_eye_electrophysiolog0.52512825
127MP0003283_abnormal_digestive_organ0.51573929
128MP0006072_abnormal_retinal_apoptosis0.51212514
129MP0009046_muscle_twitch0.50811002
130MP0004036_abnormal_muscle_relaxation0.49712696
131MP0005395_other_phenotype0.49431990
132MP0003315_abnormal_perineum_morphology0.49230293
133MP0002009_preneoplasia0.48552154
134MP0005253_abnormal_eye_physiology0.48475084
135MP0002086_abnormal_extraembryonic_tissu0.45170953
136MP0009672_abnormal_birth_weight0.44894917
137MP0005391_vision/eye_phenotype0.43945144
138MP0003861_abnormal_nervous_system0.41975666
139MP0003950_abnormal_plasma_membrane0.41686537
140MP0002019_abnormal_tumor_incidence0.40930484
141MP0000751_myopathy0.39725202
142MP0003045_fibrosis0.37829981
143MP0009703_decreased_birth_body0.36929397
144MP0003890_abnormal_embryonic-extraembry0.36261150
145MP0004742_abnormal_vestibular_system0.35661000
146MP0001293_anophthalmia0.35513502
147MP0002234_abnormal_pharynx_morphology0.35332904
148MP0000647_abnormal_sebaceous_gland0.35290167
149MP0006138_congestive_heart_failure0.34921316
150MP0001919_abnormal_reproductive_system0.33360908
151MP0002092_abnormal_eye_morphology0.32849899
152MP0000432_abnormal_head_morphology0.31918019
153MP0003221_abnormal_cardiomyocyte_apopto0.31533669
154MP0002269_muscular_atrophy0.29298540
155MP0002971_abnormal_brown_adipose0.29018862
156MP0001984_abnormal_olfaction0.27834135
157MP0005621_abnormal_cell_physiology0.27248066
158MP0001851_eye_inflammation0.27164191
159MP0003632_abnormal_nervous_system0.26348081

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)9.91264572
2Absent/shortened dynein arms (HP:0200106)9.91264572
3Abnormal respiratory motile cilium physiology (HP:0012261)7.69658721
4Rhinitis (HP:0012384)6.97390949
5Abnormal respiratory motile cilium morphology (HP:0005938)6.95469245
6Abnormal respiratory epithelium morphology (HP:0012253)6.95469245
7Abnormal ciliary motility (HP:0012262)6.14103719
8Chronic bronchitis (HP:0004469)5.82074023
9Infertility (HP:0000789)5.76481711
10Abnormality of the lower motor neuron (HP:0002366)5.69332079
11Gonadotropin excess (HP:0000837)5.39819666
12Nasal polyposis (HP:0100582)5.37548697
13Azoospermia (HP:0000027)4.74072164
14Degeneration of the lateral corticospinal tracts (HP:0002314)4.66544341
15Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.66544341
16Abnormal spermatogenesis (HP:0008669)4.58742963
17Abnormality of the nasal mucosa (HP:0000433)4.33429888
18Nephronophthisis (HP:0000090)4.32888524
19Male infertility (HP:0003251)4.21397935
20Bronchiectasis (HP:0002110)3.94088593
21Oligodactyly (hands) (HP:0001180)3.87138357
22Amyotrophic lateral sclerosis (HP:0007354)3.86463087
23Abnormality of the corticospinal tract (HP:0002492)3.84855498
24Bronchitis (HP:0012387)3.67159474
25Shoulder girdle muscle weakness (HP:0003547)3.64718940
26Fibular hypoplasia (HP:0003038)3.58412791
2711 pairs of ribs (HP:0000878)3.43837700
28Abnormality of the renal medulla (HP:0100957)3.26201915
29Horizontal nystagmus (HP:0000666)3.25586969
30Abnormality of macrophages (HP:0004311)3.20506601
31Upper motor neuron abnormality (HP:0002127)3.15796250
32Impulsivity (HP:0100710)3.15612996
33Menstrual irregularities (HP:0000858)3.14906893
34Degeneration of anterior horn cells (HP:0002398)3.03078223
35Abnormality of the anterior horn cell (HP:0006802)3.03078223
36Recurrent otitis media (HP:0000403)2.96549420
37Disinhibition (HP:0000734)2.94350505
38Tubulointerstitial nephritis (HP:0001970)2.93428098
39Abnormality of glycolipid metabolism (HP:0010969)2.92236426
40Abnormality of liposaccharide metabolism (HP:0010968)2.92236426
41Abnormality of glycosphingolipid metabolism (HP:0004343)2.92236426
42Resting tremor (HP:0002322)2.89792851
43Recurrent bacterial skin infections (HP:0005406)2.84965115
44Loss of speech (HP:0002371)2.82625554
45Rimmed vacuoles (HP:0003805)2.79933674
46Impaired vibration sensation in the lower limbs (HP:0002166)2.76430689
47Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.71178861
48Recurrent sinusitis (HP:0011108)2.71069080
49Recurrent abscess formation (HP:0002722)2.60638054
50Abnormality of DNA repair (HP:0003254)2.50463809
51Albinism (HP:0001022)2.49350325
52Selective tooth agenesis (HP:0001592)2.46776417
53Molar tooth sign on MRI (HP:0002419)2.44810026
54Abnormality of midbrain morphology (HP:0002418)2.44810026
55Scotoma (HP:0000575)2.44344333
56Oligodactyly (HP:0012165)2.44290848
57Tubular atrophy (HP:0000092)2.43952572
58Facial hemangioma (HP:0000329)2.41402903
59Impaired proprioception (HP:0010831)2.37995264
60Tubulointerstitial abnormality (HP:0001969)2.33497877
61Osteomalacia (HP:0002749)2.32012204
62Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.29774454
63Aplasia/Hypoplasia of the fibula (HP:0006492)2.26389762
64Impaired vibratory sensation (HP:0002495)2.24566529
65Recurrent bronchitis (HP:0002837)2.23883107
66Severe visual impairment (HP:0001141)2.19892262
67Widely spaced teeth (HP:0000687)2.17274064
68Spastic gait (HP:0002064)2.15681227
69Medial flaring of the eyebrow (HP:0010747)2.15679441
70Slow saccadic eye movements (HP:0000514)2.15317039
71Postaxial foot polydactyly (HP:0001830)2.14703396
72Neuronal loss in central nervous system (HP:0002529)2.10287463
73Stage 5 chronic kidney disease (HP:0003774)2.09713877
74Cutaneous melanoma (HP:0012056)2.08456032
75Inappropriate behavior (HP:0000719)2.07866472
76Increased nuchal translucency (HP:0010880)2.07265265
77Supernumerary spleens (HP:0009799)2.05784316
78Hypoplasia of the capital femoral epiphysis (HP:0003090)2.05638148
79Facial cleft (HP:0002006)2.04497645
80Short ribs (HP:0000773)2.03752839
81Macroorchidism (HP:0000053)2.03346424
82Abnormality of chromosome stability (HP:0003220)2.01269874
83Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.5458546
84Microglossia (HP:0000171)1.99315772
85Anteriorly placed anus (HP:0001545)1.98871269
86Agnosia (HP:0010524)1.97087350
87Fair hair (HP:0002286)1.96724662
88Hypoplastic iliac wings (HP:0002866)1.95443751
89Abnormality of lateral ventricle (HP:0030047)1.94537892
90Heterotopia (HP:0002282)1.93299156
91Urinary bladder sphincter dysfunction (HP:0002839)1.93160546
92Stomatitis (HP:0010280)1.91954808
93Retinal atrophy (HP:0001105)1.91229807
94Breast carcinoma (HP:0003002)1.89371777
95Absent frontal sinuses (HP:0002688)1.89171610
96Atrophy/Degeneration involving motor neurons (HP:0007373)1.87493086
97Conjunctival telangiectasia (HP:0000524)1.87034306
98Missing ribs (HP:0000921)1.85902281
99Eczematoid dermatitis (HP:0000976)1.84467815
100Ectopic kidney (HP:0000086)1.84090232
101Papillary thyroid carcinoma (HP:0002895)1.83639850
102Abnormality of chromosome segregation (HP:0002916)1.83373391
103Oculomotor apraxia (HP:0000657)1.82792498
104Metaphyseal cupping (HP:0003021)1.82362000
105Broad distal phalanx of finger (HP:0009836)1.82107097
106Abnormality of the basal ganglia (HP:0002134)1.80950117
107Episodic fever (HP:0001954)1.79961455
108Truncal obesity (HP:0001956)1.79889744
109Blepharitis (HP:0000498)1.79374957
110Lip pit (HP:0100267)1.76622007
111Rhabdomyosarcoma (HP:0002859)1.75928568
112Median cleft lip (HP:0000161)1.74242253
113Prominent nose (HP:0000448)1.73484587
114Nephrogenic diabetes insipidus (HP:0009806)1.73376495
115Low anterior hairline (HP:0000294)1.72550968
116Abnormality of ocular smooth pursuit (HP:0000617)1.71637797
117Abnormal rod and cone electroretinograms (HP:0008323)1.71602788
118Recurrent gram-negative bacterial infections (HP:0005420)1.71042019
119Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.70333776
120Tubulointerstitial fibrosis (HP:0005576)1.69500974
121Abnormality of alanine metabolism (HP:0010916)1.69253560
122Hyperalaninemia (HP:0003348)1.69253560
123Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.69253560
124Recurrent skin infections (HP:0001581)1.68917476
125Hyperpituitarism (HP:0010514)1.68757252
126Renal dysplasia (HP:0000110)1.68618779
127Hand muscle atrophy (HP:0009130)1.68218461
128Congenital hepatic fibrosis (HP:0002612)1.68217253
129Sensory axonal neuropathy (HP:0003390)1.67720683
130Capillary hemangiomas (HP:0005306)1.67033627
131Absent epiphyses (HP:0010577)1.65587560
132Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.65587560
133Abnormality of dentin (HP:0010299)1.65172528
134Male pseudohermaphroditism (HP:0000037)1.64982861
135Autoamputation (HP:0001218)1.64851293
136Generalized hypopigmentation of hair (HP:0011358)1.64580871
137Large eyes (HP:0001090)1.64565225
138Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.63105551
139Embryonal renal neoplasm (HP:0011794)1.62618382
140Hypoplasia of the fovea (HP:0007750)1.62377349
141Aplasia/Hypoplasia of the fovea (HP:0008060)1.62377349
142Duodenal stenosis (HP:0100867)1.62342626
143Small intestinal stenosis (HP:0012848)1.62342626
144Thyroid carcinoma (HP:0002890)1.62090490
145Dislocated radial head (HP:0003083)1.61602146
146Action tremor (HP:0002345)1.61538504
147Chronic diarrhea (HP:0002028)1.61071690
148Abnormal drinking behavior (HP:0030082)1.59657860
149Polydipsia (HP:0001959)1.59657860
150Increased circulating renin level (HP:0000848)1.58651439
151Abnormality of the epiphyses of the hand (HP:0005924)1.57839070
152Poor coordination (HP:0002370)1.57722710
153Sloping forehead (HP:0000340)1.57443334
154Premature ovarian failure (HP:0008209)1.57390125
155Chromsome breakage (HP:0040012)1.57032589
156Short thorax (HP:0010306)1.56483491
157Decreased motor nerve conduction velocity (HP:0003431)1.55810576
158Spontaneous abortion (HP:0005268)1.54076521
159Abnormality of the radial head (HP:0003995)1.51656542
160Chromosomal breakage induced by crosslinking agents (HP:0003221)1.51456977
161Aplasia/Hypoplasia of the tongue (HP:0010295)1.50202610
162Pancreatic fibrosis (HP:0100732)1.49581584
163Abnormality of permanent molar morphology (HP:0011071)1.49530132
164Abnormality of the dental root (HP:0006486)1.49530132
165Taurodontia (HP:0000679)1.49530132
166Abnormality of the renal cortex (HP:0011035)1.49040010
167Facial diplegia (HP:0001349)1.48847569
168Postaxial hand polydactyly (HP:0001162)1.46923495
169Clonus (HP:0002169)1.43619900
170Difficulty climbing stairs (HP:0003551)1.42641775
171Spastic tetraparesis (HP:0001285)1.42579186
172Abnormality of molar (HP:0011077)1.41462742
173Abnormality of molar morphology (HP:0011070)1.41462742
174Sandal gap (HP:0001852)1.39789084
175Cystic liver disease (HP:0006706)1.39642338
176Nephroblastoma (Wilms tumor) (HP:0002667)1.38617754
177Volvulus (HP:0002580)1.38313063
178Gaze-evoked nystagmus (HP:0000640)1.38292445

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK48.19794061
2PDK38.19794061
3PDK25.25943130
4CDK193.93006259
5CDK123.46322732
6ICK3.20956815
7PRKD33.07830905
8FRK2.99527700
9NEK22.68440722
10PNCK2.67804004
11TESK12.57678996
12CDC72.42748958
13PTK2B2.08810635
14OXSR12.06703641
15WNK41.89779983
16BRD41.88856499
17MET1.87607564
18FGR1.85087848
19MAP3K131.80078439
20NEK91.74365959
21WEE11.66026580
22STK391.56426205
23BLK1.53415130
24MST1R1.47921699
25CAMKK21.45616590
26IRAK31.42196635
27TTK1.41372224
28CSF1R1.40974006
29PLK41.40083149
30STK31.38311273
31PLK21.31825482
32TYRO31.30563961
33MAP3K91.28934502
34TYK21.22060645
35YES11.15674095
36WNK11.12578364
37IRAK21.11549239
38FGFR31.07917777
39CHEK11.03891305
40KSR21.00188488
41ATR0.99971896
42CAMK1G0.98532769
43STK380.97262503
44MAP2K30.94931785
45MOS0.92510008
46PLK10.91933565
47STK240.90503362
48IRAK40.90435587
49ACVR1B0.89595561
50EEF2K0.87765994
51CHEK20.86702679
52KSR10.86693313
53MTOR0.85144593
54RIPK40.82847594
55CDK90.80126835
56TAOK30.79696432
57NEK60.79587492
58PRPF4B0.79461074
59PASK0.78597120
60DYRK30.78219019
61MAP3K10.76646871
62SGK10.76406732
63MAP3K40.76270367
64ATM0.75917494
65DYRK1B0.75736355
66BMX0.75699192
67ZAP700.75575299
68CSK0.75419606
69FES0.74142868
70MAP3K50.72350147
71JAK20.70182166
72WNK30.68812743
73NTRK30.68620457
74CCNB10.67091308
75MAPK150.66178666
76RIPK10.66141510
77PBK0.64605115
78BMPR20.64440597
79RET0.63507163
80BUB10.62099210
81PIK3CG0.61345451
82RAF10.58852260
83PDK10.58508124
84MAP3K140.58282880
85CDK70.58135719
86BRSK20.58122983
87CAMK1D0.57691107
88STK38L0.55888524
89TRPM70.54384775
90EGFR0.52696094
91SGK30.52557570
92SGK20.51649632
93KIT0.48938783
94CDK40.46943320
95JAK30.45541218
96EIF2AK30.45213790
97PRKAA10.44697525
98DAPK20.44067699
99CDK20.43587863
100MAP3K30.41980065
101TNK20.41239933
102MAPK70.40778398
103TGFBR20.40607163
104HCK0.40139303
105CDK10.39445369
106PINK10.36214970
107STK110.35973759
108PRKD20.34462957
109SYK0.34435193
110LMTK20.34355172
111PAK20.32798524
112PRKCI0.31881414
113RPS6KB10.31827083
114AURKB0.31695555
115BTK0.30605918
116LATS10.30148788
117CAMK40.29411758
118BRSK10.29191537
119CAMK10.28714865
120MAPK110.27157685
121STK100.26394472
122PRKCZ0.26135785
123GSK3B0.24403125
124DYRK1A0.24169929
125MKNK20.23657278
126PRKDC0.23462190
127CSNK1D0.22876749
128MAPK80.22403055
129CDK30.20459881
130MELK0.19978012
131CSNK1E0.19867555
132STK40.18999288
133MAPK10.18988512
134IRAK10.18976605
135PAK10.18364850
136PIM10.18062961
137MAP3K20.18019798
138MAPK100.17196119
139SRPK10.17173162
140RPS6KA10.16783150
141PAK60.16716186
142MAPK140.16124186
143MAP3K60.15919613
144PDGFRB0.15436849
145CSNK2A20.14394735
146MARK30.14084526
147CSNK1A1L0.13877254
148AURKA0.13633694
149MUSK0.13321594
150TAOK10.12898660
151RPS6KA30.11573579
152PAK40.11514237
153NTRK20.10973979
154BRAF0.09685362
155PLK30.08731824
156CSNK2A10.08693298
157CDC42BPA0.08352917
158TRIB30.08029456
159EIF2AK10.07594429
160PRKACB0.07156358
161AKT10.06193407
162PDPK10.04485439
163CDK60.04176224
164LATS20.03974562

Predicted pathways (KEGG)

RankGene SetZ-score
1Dorso-ventral axis formation_Homo sapiens_hsa043204.67559677
2Basal transcription factors_Homo sapiens_hsa030224.39261630
3Vitamin B6 metabolism_Homo sapiens_hsa007504.28890332
4Fanconi anemia pathway_Homo sapiens_hsa034603.39318431
5RNA transport_Homo sapiens_hsa030133.17797523
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.93979602
7Selenocompound metabolism_Homo sapiens_hsa004502.92249499
8Regulation of autophagy_Homo sapiens_hsa041402.83303949
9mRNA surveillance pathway_Homo sapiens_hsa030152.62870231
10Oocyte meiosis_Homo sapiens_hsa041142.62249543
11Pyruvate metabolism_Homo sapiens_hsa006202.54582725
12Cell cycle_Homo sapiens_hsa041102.29604027
13Pentose phosphate pathway_Homo sapiens_hsa000302.27010620
14Homologous recombination_Homo sapiens_hsa034402.13869248
15Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.10858945
16Ubiquitin mediated proteolysis_Homo sapiens_hsa041202.04052270
17Other glycan degradation_Homo sapiens_hsa005112.02313492
18Fatty acid biosynthesis_Homo sapiens_hsa000611.97786794
19Osteoclast differentiation_Homo sapiens_hsa043801.95419548
20Glucagon signaling pathway_Homo sapiens_hsa049221.90605734
21Lysosome_Homo sapiens_hsa041421.83078321
22alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.74524886
23RNA degradation_Homo sapiens_hsa030181.68215096
24Linoleic acid metabolism_Homo sapiens_hsa005911.65919076
25Glycerolipid metabolism_Homo sapiens_hsa005611.59405738
26Spliceosome_Homo sapiens_hsa030401.51275337
27Propanoate metabolism_Homo sapiens_hsa006401.50169922
28Maturity onset diabetes of the young_Homo sapiens_hsa049501.48297049
29Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.47748054
30Leishmaniasis_Homo sapiens_hsa051401.47588249
31Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.45180572
32Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.45029681
33SNARE interactions in vesicular transport_Homo sapiens_hsa041301.44967867
34NOD-like receptor signaling pathway_Homo sapiens_hsa046211.43613867
35Glycerophospholipid metabolism_Homo sapiens_hsa005641.43612584
36Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.40303782
37Cysteine and methionine metabolism_Homo sapiens_hsa002701.38733506
38Antigen processing and presentation_Homo sapiens_hsa046121.33644500
39Collecting duct acid secretion_Homo sapiens_hsa049661.26378205
40Nucleotide excision repair_Homo sapiens_hsa034201.19148738
41Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.18105646
42Toll-like receptor signaling pathway_Homo sapiens_hsa046201.17505509
43p53 signaling pathway_Homo sapiens_hsa041151.14700931
44Phagosome_Homo sapiens_hsa041451.14423654
45Lysine degradation_Homo sapiens_hsa003101.13097264
46Purine metabolism_Homo sapiens_hsa002301.12009630
47Tuberculosis_Homo sapiens_hsa051521.09414867
48Type II diabetes mellitus_Homo sapiens_hsa049301.07751570
49Pyrimidine metabolism_Homo sapiens_hsa002400.99958266
50Huntingtons disease_Homo sapiens_hsa050160.99629935
51Non-homologous end-joining_Homo sapiens_hsa034500.95040447
52B cell receptor signaling pathway_Homo sapiens_hsa046620.92065090
53RNA polymerase_Homo sapiens_hsa030200.90330923
54Base excision repair_Homo sapiens_hsa034100.90080767
55RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.88580878
56Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.88401064
57DNA replication_Homo sapiens_hsa030300.86729276
58Measles_Homo sapiens_hsa051620.84983957
59Sphingolipid signaling pathway_Homo sapiens_hsa040710.83706728
60Acute myeloid leukemia_Homo sapiens_hsa052210.81824512
61Thyroid hormone signaling pathway_Homo sapiens_hsa049190.78098366
62Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.78062263
63Carbohydrate digestion and absorption_Homo sapiens_hsa049730.77248049
64Chemokine signaling pathway_Homo sapiens_hsa040620.76873908
65Epstein-Barr virus infection_Homo sapiens_hsa051690.76666749
66Rheumatoid arthritis_Homo sapiens_hsa053230.76335142
67Choline metabolism in cancer_Homo sapiens_hsa052310.73697589
68Circadian rhythm_Homo sapiens_hsa047100.72985882
69TNF signaling pathway_Homo sapiens_hsa046680.70862732
70T cell receptor signaling pathway_Homo sapiens_hsa046600.70397479
71Non-small cell lung cancer_Homo sapiens_hsa052230.69319323
72Estrogen signaling pathway_Homo sapiens_hsa049150.67847751
73Viral carcinogenesis_Homo sapiens_hsa052030.67841217
74Amphetamine addiction_Homo sapiens_hsa050310.67384675
75Biosynthesis of amino acids_Homo sapiens_hsa012300.66964858
76Central carbon metabolism in cancer_Homo sapiens_hsa052300.66891715
77Herpes simplex infection_Homo sapiens_hsa051680.66359718
78Inositol phosphate metabolism_Homo sapiens_hsa005620.64367435
79FoxO signaling pathway_Homo sapiens_hsa040680.64028012
80Mismatch repair_Homo sapiens_hsa034300.63871059
81Jak-STAT signaling pathway_Homo sapiens_hsa046300.62387481
82Proteasome_Homo sapiens_hsa030500.62055462
83Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.61304328
84Ether lipid metabolism_Homo sapiens_hsa005650.60552371
85Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.60204819
86ErbB signaling pathway_Homo sapiens_hsa040120.59072278
87PPAR signaling pathway_Homo sapiens_hsa033200.58087255
88Hematopoietic cell lineage_Homo sapiens_hsa046400.57512766
89Synaptic vesicle cycle_Homo sapiens_hsa047210.56551387
90Carbon metabolism_Homo sapiens_hsa012000.56533804
91GnRH signaling pathway_Homo sapiens_hsa049120.56459386
92Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.56367460
93Vitamin digestion and absorption_Homo sapiens_hsa049770.55901225
94Hepatitis B_Homo sapiens_hsa051610.55484289
95Longevity regulating pathway - mammal_Homo sapiens_hsa042110.55449313
96HTLV-I infection_Homo sapiens_hsa051660.55065753
97Long-term depression_Homo sapiens_hsa047300.54687815
98Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.54199954
99Influenza A_Homo sapiens_hsa051640.53775705
100ABC transporters_Homo sapiens_hsa020100.53635956
101Salmonella infection_Homo sapiens_hsa051320.53147075
102Systemic lupus erythematosus_Homo sapiens_hsa053220.51170618
103Transcriptional misregulation in cancer_Homo sapiens_hsa052020.50972799
104Staphylococcus aureus infection_Homo sapiens_hsa051500.50435318
105Platelet activation_Homo sapiens_hsa046110.50340170
106Hedgehog signaling pathway_Homo sapiens_hsa043400.50193205
107Malaria_Homo sapiens_hsa051440.49832167
108AMPK signaling pathway_Homo sapiens_hsa041520.48920755
109mTOR signaling pathway_Homo sapiens_hsa041500.48417966
110Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48415869
111Amoebiasis_Homo sapiens_hsa051460.48326290
112NF-kappa B signaling pathway_Homo sapiens_hsa040640.47832693
113Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.46917679
114Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.46183739
115Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.45863367
116Fat digestion and absorption_Homo sapiens_hsa049750.45551531
117Glycosaminoglycan degradation_Homo sapiens_hsa005310.44583044
118Ovarian steroidogenesis_Homo sapiens_hsa049130.44327910
119Calcium signaling pathway_Homo sapiens_hsa040200.43595405
120Renin secretion_Homo sapiens_hsa049240.43282059
121Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.42349862
122N-Glycan biosynthesis_Homo sapiens_hsa005100.41206010
123Phospholipase D signaling pathway_Homo sapiens_hsa040720.41102812
124VEGF signaling pathway_Homo sapiens_hsa043700.40779361
125Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.39869747
126beta-Alanine metabolism_Homo sapiens_hsa004100.36760939
127Adipocytokine signaling pathway_Homo sapiens_hsa049200.36752357
128Long-term potentiation_Homo sapiens_hsa047200.36401518
129cGMP-PKG signaling pathway_Homo sapiens_hsa040220.36038533
130Notch signaling pathway_Homo sapiens_hsa043300.35837337
131Phototransduction_Homo sapiens_hsa047440.35805490
132Small cell lung cancer_Homo sapiens_hsa052220.35092092
133MAPK signaling pathway_Homo sapiens_hsa040100.34837172
134Mineral absorption_Homo sapiens_hsa049780.34344713
135Prolactin signaling pathway_Homo sapiens_hsa049170.34090132
136HIF-1 signaling pathway_Homo sapiens_hsa040660.32831375
137Legionellosis_Homo sapiens_hsa051340.32820717
138Fatty acid metabolism_Homo sapiens_hsa012120.32697984
139Shigellosis_Homo sapiens_hsa051310.32342332
140TGF-beta signaling pathway_Homo sapiens_hsa043500.32199196
141Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.32183826
142Endocytosis_Homo sapiens_hsa041440.28535204
143Wnt signaling pathway_Homo sapiens_hsa043100.28434382
144Fructose and mannose metabolism_Homo sapiens_hsa000510.28121440
145Tight junction_Homo sapiens_hsa045300.24540954
146Alcoholism_Homo sapiens_hsa050340.23705457
147Prostate cancer_Homo sapiens_hsa052150.22790322
148Toxoplasmosis_Homo sapiens_hsa051450.21601140
149Sphingolipid metabolism_Homo sapiens_hsa006000.20565907
150Protein digestion and absorption_Homo sapiens_hsa049740.18494657
151Basal cell carcinoma_Homo sapiens_hsa052170.16049956
152ECM-receptor interaction_Homo sapiens_hsa045120.15441562
153Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.12849657
154Arachidonic acid metabolism_Homo sapiens_hsa005900.12067055
155Glutathione metabolism_Homo sapiens_hsa004800.11257014
156Vascular smooth muscle contraction_Homo sapiens_hsa042700.10365545

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