TEAD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane repair (GO:0001778)4.63428871
2cardiac myofibril assembly (GO:0055003)4.42588633
3sarcomere organization (GO:0045214)4.12720127
4actin-myosin filament sliding (GO:0033275)3.88069302
5muscle filament sliding (GO:0030049)3.88069302
6* hippo signaling (GO:0035329)3.82017515
7myofibril assembly (GO:0030239)3.68953907
8chondrocyte proliferation (GO:0035988)3.68016761
9actin-mediated cell contraction (GO:0070252)3.55574902
10* paraxial mesoderm development (GO:0048339)3.54548301
11endocardial cushion development (GO:0003197)3.52921809
12planar cell polarity pathway involved in neural tube closure (GO:0090179)3.47399091
13regulation of cardioblast differentiation (GO:0051890)3.42253376
14epithelial cell-cell adhesion (GO:0090136)3.40724727
15regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.35844091
16negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.35225762
17skin morphogenesis (GO:0043589)3.33780437
18polarized epithelial cell differentiation (GO:0030859)3.30260472
19regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.29080175
20bone trabecula formation (GO:0060346)3.24906809
21cardiac muscle cell development (GO:0055013)3.22463587
22collagen fibril organization (GO:0030199)3.21740118
23axon extension involved in axon guidance (GO:0048846)3.19704592
24neuron projection extension involved in neuron projection guidance (GO:1902284)3.19704592
25atrial septum morphogenesis (GO:0060413)3.15498380
26actomyosin structure organization (GO:0031032)3.14599973
27cardiac cell development (GO:0055006)3.12391381
28regulation of SMAD protein import into nucleus (GO:0060390)3.09391031
29basement membrane organization (GO:0071711)3.06085684
30insulin-like growth factor receptor signaling pathway (GO:0048009)3.05309832
31regulation of skeletal muscle contraction (GO:0014819)3.04318151
32cell migration involved in sprouting angiogenesis (GO:0002042)3.02448112
33positive regulation of SMAD protein import into nucleus (GO:0060391)3.00662474
34endothelial cell morphogenesis (GO:0001886)2.99498030
35negative regulation of potassium ion transmembrane transport (GO:1901380)2.99405743
36regulation of hippo signaling (GO:0035330)2.98238070
37anterior/posterior axis specification, embryo (GO:0008595)2.97008091
38actin filament-based movement (GO:0030048)2.96099660
39negative regulation of chondrocyte differentiation (GO:0032331)2.95031421
40regulation of heart morphogenesis (GO:2000826)2.93970814
41glomerular basement membrane development (GO:0032836)2.91559022
42endodermal cell differentiation (GO:0035987)2.88130845
43sequestering of extracellular ligand from receptor (GO:0035581)2.87035972
44protein heterotrimerization (GO:0070208)2.83924986
45G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.82471197
46regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.80705269
47heart morphogenesis (GO:0003007)2.77623865
48regulation of tight junction assembly (GO:2000810)2.77586534
49outer ear morphogenesis (GO:0042473)2.76198022
50outflow tract septum morphogenesis (GO:0003148)2.75786799
51negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.75015444
52atrioventricular valve morphogenesis (GO:0003181)2.74396624
53metanephric mesenchyme development (GO:0072075)2.74332934
54cardiac muscle tissue morphogenesis (GO:0055008)2.71472619
55renal filtration (GO:0097205)2.71432848
56regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.70871723
57lateral sprouting from an epithelium (GO:0060601)2.70029209
58trabecula formation (GO:0060343)2.69580814
59gastrulation with mouth forming second (GO:0001702)2.67809706
60retina vasculature morphogenesis in camera-type eye (GO:0061299)2.67361966
61* mesenchyme development (GO:0060485)2.67088426
62negative regulation of striated muscle cell apoptotic process (GO:0010664)2.67057335
63heart trabecula formation (GO:0060347)2.66815194
64hemidesmosome assembly (GO:0031581)2.66708899
65adherens junction assembly (GO:0034333)2.66616667
66bundle of His cell to Purkinje myocyte communication (GO:0086069)2.66099661
67regulation of cell proliferation involved in heart morphogenesis (GO:2000136)2.65406661
68negative regulation of catenin import into nucleus (GO:0035414)2.64075329
69cell-substrate junction assembly (GO:0007044)2.63138692
70craniofacial suture morphogenesis (GO:0097094)2.63041714
71pericardium development (GO:0060039)2.62828089
72cochlea morphogenesis (GO:0090103)2.61931670
73cell migration involved in heart development (GO:0060973)2.61314661
74negative regulation of fatty acid transport (GO:2000192)2.60316582
75vascular endothelial growth factor signaling pathway (GO:0038084)2.60021948
76establishment of apical/basal cell polarity (GO:0035089)2.59825330
77kidney mesenchyme development (GO:0072074)2.58608045
78lymphangiogenesis (GO:0001946)2.58398613
79Golgi transport vesicle coating (GO:0048200)2.56669284
80COPI coating of Golgi vesicle (GO:0048205)2.56669284
81muscle tissue morphogenesis (GO:0060415)2.56390154
82myoblast fusion (GO:0007520)2.56384084
83negative regulation of axon extension involved in axon guidance (GO:0048843)2.56243808
84positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.55790419
85regulation of cardioblast proliferation (GO:0003264)2.55611798
86regulation of secondary heart field cardioblast proliferation (GO:0003266)2.55611798
87negative regulation of cartilage development (GO:0061037)2.55209775
88ventricular cardiac muscle tissue morphogenesis (GO:0055010)2.54629687
89muscle cell migration (GO:0014812)2.54212408
90adult heart development (GO:0007512)2.54147707
91desmosome organization (GO:0002934)2.53665530
92cardiac muscle contraction (GO:0060048)2.53606662
93regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.52543366
94substrate adhesion-dependent cell spreading (GO:0034446)2.51680078
95regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.49296034
96branching involved in salivary gland morphogenesis (GO:0060445)2.48600968
97convergent extension (GO:0060026)2.48538768
98glomerular filtration (GO:0003094)2.47570767
99positive regulation of epithelial to mesenchymal transition (GO:0010718)2.47183098
100regulation of transforming growth factor beta2 production (GO:0032909)2.46998407
101regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.46643001
102cardiac right ventricle morphogenesis (GO:0003215)2.45503052
103Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.45262739
104mesenchymal-epithelial cell signaling (GO:0060638)2.43799782
105cell adhesion mediated by integrin (GO:0033627)2.43409468
106nuclear pore complex assembly (GO:0051292)2.43147683
107regulation of establishment of planar polarity (GO:0090175)2.42669972
108NLS-bearing protein import into nucleus (GO:0006607)2.42647980
109positive regulation of mesenchymal cell proliferation (GO:0002053)2.42269617
110protein localization to cell surface (GO:0034394)2.42218333
111cellular response to vitamin (GO:0071295)2.41607143
112regulation of axon extension involved in axon guidance (GO:0048841)2.40998777
113dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.40581589
114regulation of catenin import into nucleus (GO:0035412)2.40123524
115regulation of cell fate specification (GO:0042659)2.40092972
116ventricular cardiac muscle cell development (GO:0055015)2.39555337
117cell-substrate adherens junction assembly (GO:0007045)2.39435819
118focal adhesion assembly (GO:0048041)2.39435819
119morphogenesis of an epithelial sheet (GO:0002011)2.38535598
120regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.34210136
121embryonic foregut morphogenesis (GO:0048617)2.33281143
122non-canonical Wnt signaling pathway (GO:0035567)2.32315920
123negative regulation of stem cell proliferation (GO:2000647)2.29046492
124mesodermal cell differentiation (GO:0048333)2.28532722
125protein hydroxylation (GO:0018126)2.28391516
126collagen metabolic process (GO:0032963)2.28347383
127cytoskeletal anchoring at plasma membrane (GO:0007016)2.27945451
128embryonic cranial skeleton morphogenesis (GO:0048701)2.26983766
129substrate-dependent cell migration (GO:0006929)2.26676515
130actin filament depolymerization (GO:0030042)2.25368639
131cellular response to vitamin D (GO:0071305)2.23846827
132peripheral nervous system axon ensheathment (GO:0032292)2.23726311
133myelination in peripheral nervous system (GO:0022011)2.23726311
134extracellular matrix assembly (GO:0085029)2.23574114
135midgut development (GO:0007494)2.23522688
136chondrocyte development (GO:0002063)2.21900955
137glomerular visceral epithelial cell development (GO:0072015)2.21559018
138gap junction assembly (GO:0016264)2.19550211
139positive regulation of catenin import into nucleus (GO:0035413)2.19226386
140smooth muscle tissue development (GO:0048745)2.18745014
141mitotic cytokinesis (GO:0000281)2.18259723
142syncytium formation by plasma membrane fusion (GO:0000768)2.17155341
143maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.16924457

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.54304835
2TRIM28_21343339_ChIP-Seq_HEK293_Human4.16838227
3RBPJ_22232070_ChIP-Seq_NCS_Mouse3.08514928
4SALL1_21062744_ChIP-ChIP_HESCs_Human2.85237390
5RARG_19884340_ChIP-ChIP_MEFs_Mouse2.80281905
6EP300_21415370_ChIP-Seq_HL-1_Mouse2.69973560
7EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.53695867
8FOXM1_23109430_ChIP-Seq_U2OS_Human2.49654480
9HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.39511204
10* SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.38798510
11NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.37432228
12NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.27537763
13ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.27035020
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.26611518
15CLOCK_20551151_ChIP-Seq_293T_Human2.23006227
16ZIC3_20872845_ChIP-ChIP_MESCs_Mouse2.17113977
17WT1_19549856_ChIP-ChIP_CCG9911_Human2.16253276
18TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.10562025
19HIF1A_21447827_ChIP-Seq_MCF-7_Human2.05656471
20SALL4_18804426_ChIP-ChIP_MESCs_Mouse2.00335262
21WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.91868317
22TP63_19390658_ChIP-ChIP_HaCaT_Human1.88858903
23* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.88102767
24* ISL1_27105846_Chip-Seq_CPCs_Mouse1.85995526
25RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.80949459
26TCF3_18692474_ChIP-Seq_MEFs_Mouse1.80497148
27* BRD4_25478319_ChIP-Seq_HGPS_Human1.78057153
28EGR1_19374776_ChIP-ChIP_THP-1_Human1.76933860
29MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.76741539
30* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.74684185
31KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.73871959
32KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.73871959
33KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.73871959
34TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.67956961
35SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.65639289
36SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.62315013
37* TBX20_22080862_ChIP-Seq_HEART_Mouse1.61999890
38* TBX20_22328084_ChIP-Seq_HEART_Mouse1.61999890
39CJUN_26792858_Chip-Seq_BT549_Human1.61548652
40ESR1_21235772_ChIP-Seq_MCF-7_Human1.60772267
41ZFP281_18757296_ChIP-ChIP_E14_Mouse1.60548982
42PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.58816061
43* TP53_18474530_ChIP-ChIP_U2OS_Human1.57875761
44AR_21909140_ChIP-Seq_LNCAP_Human1.55906818
45TP53_20018659_ChIP-ChIP_R1E_Mouse1.55828626
46CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.55676075
47* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.55008255
48ESR1_20079471_ChIP-ChIP_T-47D_Human1.54688180
49* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.52060168
50SALL4_18804426_ChIP-ChIP_XEN_Mouse1.51633439
51SMAD_19615063_ChIP-ChIP_OVARY_Human1.49376137
52* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.48641842
53TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.47403774
54FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.45607580
55PIAS1_25552417_ChIP-Seq_VCAP_Human1.44700353
56TCF3_18692474_ChIP-Seq_MESCs_Mouse1.44381853
57POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.41010409
58ZFP281_27345836_Chip-Seq_ESCs_Mouse1.40641897
59* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.38678764
60NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.38283429
61ESR2_21235772_ChIP-Seq_MCF-7_Human1.37035424
62SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.35137887
63SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.35137887
64* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.34779045
65NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.34582455
66* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.32509470
67STAT6_21828071_ChIP-Seq_BEAS2B_Human1.30401817
68ESR1_15608294_ChIP-ChIP_MCF-7_Human1.27955284
69TCF4_18268006_ChIP-ChIP_LS174T_Human1.27919932
70* TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.27876936
71YAP1_20516196_ChIP-Seq_MESCs_Mouse1.26767587
72* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.25493941
73EED_16625203_ChIP-ChIP_MESCs_Mouse1.24866893
74SOX2_18555785_ChIP-Seq_MESCs_Mouse1.24827495
75UBF1/2_26484160_Chip-Seq_HMECs_Human1.23246355
76NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.22270088
77TBX3_20139965_ChIP-Seq_ESCs_Mouse1.21613640
78TBX3_20139965_ChIP-Seq_MESCs_Mouse1.20184741
79* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.19199224
80TP53_16413492_ChIP-PET_HCT116_Human1.18578965
81CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18270266
82PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.17312326
83EZH2_18974828_ChIP-Seq_MESCs_Mouse1.16982279
84RNF2_18974828_ChIP-Seq_MESCs_Mouse1.16982279
85* AHR_22903824_ChIP-Seq_MCF-7_Human1.16764332
86GATA4_21415370_ChIP-Seq_HL-1_Mouse1.16294734
87* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.14040921
88* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.13921716
89NANOG_21062744_ChIP-ChIP_HESCs_Human1.12030845
90TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.11363262
91NANOG_16153702_ChIP-ChIP_HESCs_Human1.11272975
92RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.10699017
93* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.09575088
94NFIB_24661679_ChIP-Seq_LUNG_Mouse1.09548875
95GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.09280349
96* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.08876230
97FOXO3_23340844_ChIP-Seq_DLD1_Human1.08278489
98* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.08277381
99RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08082110
100ZNF263_19887448_ChIP-Seq_K562_Human1.07998189
101* EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.07041930
102* ARNT_22903824_ChIP-Seq_MCF-7_Human1.06962772
103PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.05903775
104* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.04698759
105PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.04237737
106* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.02836688
107E2F7_22180533_ChIP-Seq_HELA_Human1.01673554
108* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.01186798
109KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.01019556
110* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00970443
111* ATF3_27146783_Chip-Seq_COLON_Human1.00805069
112AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.00577580
113* POU5F1_16518401_ChIP-PET_MESCs_Mouse0.99883500
114NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.99414613
115NRF2_20460467_ChIP-Seq_MEFs_Mouse0.99414613
116SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.98506084
117BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.98127108
118* TP53_23651856_ChIP-Seq_MEFs_Mouse0.97483972
119ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.96771671
120* PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.96492981
121STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.96397208
122SOX9_26525672_Chip-Seq_HEART_Mouse0.96168179
123RING1B_27294783_Chip-Seq_NPCs_Mouse0.96118861
124POU5F1_16153702_ChIP-ChIP_HESCs_Human0.95703362
125PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.95551942
126GBX2_23144817_ChIP-Seq_PC3_Human0.95409334
127PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.95377366
128SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.94604105
129SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.92970918

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen3.38023127
2MP0003705_abnormal_hypodermis_morpholog2.92418862
3MP0004272_abnormal_basement_membrane2.71989434
4MP0005503_abnormal_tendon_morphology2.69885337
5MP0004084_abnormal_cardiac_muscle2.58199722
6MP0005275_abnormal_skin_tensile2.55807025
7MP0005623_abnormal_meninges_morphology2.52401476
8MP0010030_abnormal_orbit_morphology2.39309477
9MP0000751_myopathy2.26182235
10MP0003941_abnormal_skin_development2.10795877
11MP0002837_dystrophic_cardiac_calcinosis1.99656559
12MP0009780_abnormal_chondrocyte_physiolo1.97121026
13MP0003279_aneurysm1.96676974
14MP0009053_abnormal_anal_canal1.94099767
15MP0000749_muscle_degeneration1.89804763
16MP0000733_abnormal_muscle_development1.86370979
17MP0003385_abnormal_body_wall1.85741827
18MP0009384_cardiac_valve_regurgitation1.84154952
19MP0000537_abnormal_urethra_morphology1.83712716
20MP0000750_abnormal_muscle_regeneration1.82778321
21MP0004087_abnormal_muscle_fiber1.78587025
22MP0003566_abnormal_cell_adhesion1.76055232
23MP0000013_abnormal_adipose_tissue1.73383308
24MP0003567_abnormal_fetal_cardiomyocyte1.72783354
25MP0010352_gastrointestinal_tract_polyps1.71282233
26MP0004233_abnormal_muscle_weight1.67172376
27MP0005330_cardiomyopathy1.66789206
28MP0009250_abnormal_appendicular_skeleto1.61991683
29MP0002108_abnormal_muscle_morphology1.60717549
30MP0004215_abnormal_myocardial_fiber1.60277491
31MP0002877_abnormal_melanocyte_morpholog1.59116734
32* MP0010630_abnormal_cardiac_muscle1.56509771
33MP0003942_abnormal_urinary_system1.54588186
34MP0006138_congestive_heart_failure1.53792534
35MP0004036_abnormal_muscle_relaxation1.50827850
36MP0003937_abnormal_limbs/digits/tail_de1.49829865
37MP0001958_emphysema1.49153820
38MP0003122_maternal_imprinting1.48914806
39MP0000428_abnormal_craniofacial_morphol1.43740474
40MP0003755_abnormal_palate_morphology1.43531712
41MP0004145_abnormal_muscle_electrophysio1.42717124
42MP0005171_absent_coat_pigmentation1.40236772
43MP0000534_abnormal_ureter_morphology1.39669974
44MP0003935_abnormal_craniofacial_develop1.39004679
45MP0002972_abnormal_cardiac_muscle1.38307577
46MP0005508_abnormal_skeleton_morphology1.37602784
47MP0005620_abnormal_muscle_contractility1.35182280
48MP0008775_abnormal_heart_ventricle1.34863592
49MP0003123_paternal_imprinting1.34078957
50MP0002060_abnormal_skin_morphology1.33639375
51MP0000049_abnormal_middle_ear1.31996409
52MP0005369_muscle_phenotype1.30981209
53MP0003115_abnormal_respiratory_system1.30848898
54MP0001299_abnormal_eye_distance/1.30648251
55MP0010368_abnormal_lymphatic_system1.30438805
56MP0002106_abnormal_muscle_physiology1.30172005
57MP0000759_abnormal_skeletal_muscle1.30094918
58MP0003950_abnormal_plasma_membrane1.29151145
59MP0000762_abnormal_tongue_morphology1.28571278
60MP0005076_abnormal_cell_differentiation1.28466258
61MP0000003_abnormal_adipose_tissue1.26012540
62MP0003137_abnormal_impulse_conducting1.25630461
63MP0003828_pulmonary_edema1.24608595
64MP0003283_abnormal_digestive_organ1.23132762
65MP0002269_muscular_atrophy1.23006484
66MP0004197_abnormal_fetal_growth/weight/1.22688491
67MP0005385_cardiovascular_system_phenoty1.22488097
68MP0001544_abnormal_cardiovascular_syste1.22488097
69MP0005367_renal/urinary_system_phenotyp1.21405176
70MP0000516_abnormal_urinary_system1.21405176
71MP0002249_abnormal_larynx_morphology1.20925450
72MP0003121_genomic_imprinting1.19351633
73MP0000432_abnormal_head_morphology1.17889280
74MP0002234_abnormal_pharynx_morphology1.14585868
75MP0002932_abnormal_joint_morphology1.13252593
76MP0005409_darkened_coat_color1.12597194
77MP0003119_abnormal_digestive_system1.12125028
78MP0002127_abnormal_cardiovascular_syste1.11926461
79MP0005248_abnormal_Harderian_gland1.10526735
80* MP0002925_abnormal_cardiovascular_devel1.10266540
81MP0003091_abnormal_cell_migration1.09918701
82* MP0002084_abnormal_developmental_patter1.07276787
83MP0000747_muscle_weakness1.07087815
84MP0001661_extended_life_span1.06932799
85* MP0000266_abnormal_heart_morphology1.06904247
86MP0000767_abnormal_smooth_muscle1.06157233
87MP0000566_synostosis1.05376239
88MP0002896_abnormal_bone_mineralization1.05178907
89MP0002697_abnormal_eye_size1.04481741
90* MP0003984_embryonic_growth_retardation1.04235986
91MP0002116_abnormal_craniofacial_bone1.04174673
92* MP0002088_abnormal_embryonic_growth/wei1.03800420
93MP0001293_anophthalmia1.03649184
94MP0002233_abnormal_nose_morphology1.03311695
95MP0000462_abnormal_digestive_system1.03268616
96MP0003646_muscle_fatigue1.03170089
97MP0002282_abnormal_trachea_morphology1.02789137
98MP0005197_abnormal_uvea_morphology1.01513516
99MP0005257_abnormal_intraocular_pressure1.01244967
100* MP0002085_abnormal_embryonic_tissue1.00889658
101MP0004858_abnormal_nervous_system1.00830428
102MP0005023_abnormal_wound_healing1.00130569
103MP0004484_altered_response_of0.99903264
104* MP0005380_embryogenesis_phenotype0.98709533
105* MP0001672_abnormal_embryogenesis/_devel0.98709533
106MP0001879_abnormal_lymphatic_vessel0.96515766
107MP0006054_spinal_hemorrhage0.96293727
108MP0005187_abnormal_penis_morphology0.96274305
109MP0002938_white_spotting0.94685715
110MP0000579_abnormal_nail_morphology0.94414926
111MP0002128_abnormal_blood_circulation0.92661101
112MP0002295_abnormal_pulmonary_circulatio0.90752336
113MP0000163_abnormal_cartilage_morphology0.88763134
114MP0002092_abnormal_eye_morphology0.83478632
115MP0001243_abnormal_dermal_layer0.83383279
116MP0001849_ear_inflammation0.80767601
117MP0002114_abnormal_axial_skeleton0.78881011
118MP0001348_abnormal_lacrimal_gland0.78119315
119MP0001542_abnormal_bone_strength0.77186202
120MP0004134_abnormal_chest_morphology0.76755422
121MP0005595_abnormal_vascular_smooth0.72336880
122MP0001286_abnormal_eye_development0.72156850
123MP0005375_adipose_tissue_phenotype0.69391186
124MP0010234_abnormal_vibrissa_follicle0.69270552
125MP0005193_abnormal_anterior_eye0.67910044

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)4.30735825
2Premature rupture of membranes (HP:0001788)3.85414825
3Shallow orbits (HP:0000586)3.72700597
4Vascular tortuosity (HP:0004948)3.52976541
5Type 1 muscle fiber predominance (HP:0003803)3.45310578
6Arterial tortuosity (HP:0005116)3.39156521
7Increased connective tissue (HP:0009025)3.37517938
8Muscle fiber splitting (HP:0003555)3.18626847
9Right ventricular cardiomyopathy (HP:0011663)3.16952672
10Sudden death (HP:0001699)3.15961583
11Ankle contracture (HP:0006466)3.07802707
12Hyporeflexia of lower limbs (HP:0002600)2.95698368
13Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.93267548
14Short 4th metacarpal (HP:0010044)2.93267548
15Abnormality of the calf musculature (HP:0001430)2.86693041
16Ventricular tachycardia (HP:0004756)2.82747734
17Broad metatarsal (HP:0001783)2.82643119
18Exercise-induced muscle cramps (HP:0003710)2.78275158
19Atrophic scars (HP:0001075)2.73946248
20Subaortic stenosis (HP:0001682)2.64976963
21Abnormality of the left ventricular outflow tract (HP:0011103)2.64976963
22Hypoplastic ischia (HP:0003175)2.61457057
23Cerebral aneurysm (HP:0004944)2.58156899
24Spinal rigidity (HP:0003306)2.54283606
25Abnormality of the 4th metacarpal (HP:0010012)2.52413419
26Ulnar bowing (HP:0003031)2.50032684
27Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.48794987
28Calf muscle hypertrophy (HP:0008981)2.48099751
29Mildly elevated creatine phosphokinase (HP:0008180)2.47225490
30Round ear (HP:0100830)2.46973099
31Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.45828909
32Hip contracture (HP:0003273)2.44358229
33Muscle fiber inclusion bodies (HP:0100299)2.44187190
34Atrial fibrillation (HP:0005110)2.40992045
35Aortic dissection (HP:0002647)2.40665159
36Lipoatrophy (HP:0100578)2.39697521
37Aortic aneurysm (HP:0004942)2.35248251
38Calcaneovalgus deformity (HP:0001848)2.33643926
39Difficulty running (HP:0009046)2.33387893
40Osteolytic defects of the phalanges of the hand (HP:0009771)2.30036337
41Osteolytic defects of the hand bones (HP:0009699)2.30036337
42Abnormality of the ischium (HP:0003174)2.28274350
43Scapular winging (HP:0003691)2.27064796
44Muscle hypertrophy of the lower extremities (HP:0008968)2.27010205
45Bladder diverticulum (HP:0000015)2.26916797
46Wrist flexion contracture (HP:0001239)2.25818145
47Primary atrial arrhythmia (HP:0001692)2.24925090
48Short nail (HP:0001799)2.19667782
49Difficulty climbing stairs (HP:0003551)2.18075801
50Soft skin (HP:0000977)2.16827880
51Exercise-induced myalgia (HP:0003738)2.16195373
52Follicular hyperkeratosis (HP:0007502)2.14877528
53Supraventricular arrhythmia (HP:0005115)2.14839928
54Deformed tarsal bones (HP:0008119)2.13769904
55Supraventricular tachycardia (HP:0004755)2.09728393
56EMG: myopathic abnormalities (HP:0003458)2.06108855
57Slender build (HP:0001533)2.05984305
58Cervical subluxation (HP:0003308)2.05077704
59Fragile skin (HP:0001030)2.04137037
60Increased variability in muscle fiber diameter (HP:0003557)2.02766425
61Neonatal short-limb short stature (HP:0008921)2.02726714
62Limited hip movement (HP:0008800)2.02170614
63Mesomelia (HP:0003027)2.01982599
64Ulnar deviation of the wrist (HP:0003049)1.96494779
65Elbow flexion contracture (HP:0002987)1.96193258
66Mitral regurgitation (HP:0001653)1.96027668
67Wide anterior fontanel (HP:0000260)1.95796605
68Hepatoblastoma (HP:0002884)1.92347535
69Dilatation of the ascending aorta (HP:0005111)1.91278684
70Abnormality of dentin (HP:0010299)1.91154527
71Nemaline bodies (HP:0003798)1.90639044
72Mitral valve prolapse (HP:0001634)1.90334335
73Coronal craniosynostosis (HP:0004440)1.90116935
74Rectal prolapse (HP:0002035)1.89226157
75Aneurysm (HP:0002617)1.88630401
76Lymphangioma (HP:0100764)1.87879264
77Genu recurvatum (HP:0002816)1.87835392
78Hyperextensible skin (HP:0000974)1.87518677
79Overgrowth (HP:0001548)1.87045289
80Abnormality of skeletal muscle fiber size (HP:0012084)1.86817024
81Broad thumb (HP:0011304)1.84542919
82Breech presentation (HP:0001623)1.83930537
83Bell-shaped thorax (HP:0001591)1.83124203
84Renal duplication (HP:0000075)1.79861051
85Absent frontal sinuses (HP:0002688)1.79333000
86Neck muscle weakness (HP:0000467)1.79092490
87Natal tooth (HP:0000695)1.78386086
88Wormian bones (HP:0002645)1.77415962
89Syringomyelia (HP:0003396)1.77048402
90Spinal cord lesions (HP:0100561)1.77048402
91Vertebral compression fractures (HP:0002953)1.76582025
92Mitral stenosis (HP:0001718)1.75720008
93Broad toe (HP:0001837)1.75063774
94Abnormal delivery (HP:0001787)1.74595457
95Aortic regurgitation (HP:0001659)1.74011095
96Broad long bones (HP:0005622)1.73363189
97Hypoplasia of the iris (HP:0007676)1.71620348
98Cardiovascular calcification (HP:0011915)1.71005590
99Dilated cardiomyopathy (HP:0001644)1.70917044
100Abnormality of the calcaneus (HP:0008364)1.70730354
101Limb-girdle muscle atrophy (HP:0003797)1.70630124
102Blue sclerae (HP:0000592)1.70386336
103Knee flexion contracture (HP:0006380)1.70154529
104Abnormality of the pubic bones (HP:0003172)1.70115890
105Vertebral arch anomaly (HP:0008438)1.69045794
106Pterygium (HP:0001059)1.68536013
107Asymmetry of the thorax (HP:0001555)1.67837189
108Thin ribs (HP:0000883)1.67453562
109Distal arthrogryposis (HP:0005684)1.66736105
110Abnormality of the acetabulum (HP:0003170)1.66291969
111Broad face (HP:0000283)1.65909768
112Spondylolisthesis (HP:0003302)1.65026659
113Camptodactyly of toe (HP:0001836)1.64844355
114Abnormality of the shoulder girdle musculature (HP:0001435)1.64440952
115Biconcave vertebral bodies (HP:0004586)1.64425141
116Distal lower limb muscle weakness (HP:0009053)1.63373195
117Abnormality of the distal phalanx of the thumb (HP:0009617)1.62997317
118Hyperacusis (HP:0010780)1.62521966
119Limb-girdle muscle weakness (HP:0003325)1.62398016
120Short hallux (HP:0010109)1.61346495
121Bundle branch block (HP:0011710)1.60724313
122Broad phalanx (HP:0006009)1.59999079
123Abnormality of the nasal septum (HP:0000419)1.59541705
124Selective tooth agenesis (HP:0001592)1.59345187
125Tarsal synostosis (HP:0008368)1.59241157
126Lower limb amyotrophy (HP:0007210)1.59022360
127Bowel diverticulosis (HP:0005222)1.58900590
128Preaxial foot polydactyly (HP:0001841)1.57564731
129Broad finger (HP:0001500)1.56549302
130Broad phalanges of the hand (HP:0009768)1.55539505
131Deviation of the hallux (HP:0010051)1.54254188
132Ventricular arrhythmia (HP:0004308)1.54142716
133Aplasia/Hypoplasia of the hallux (HP:0008362)1.52451924
134Short humerus (HP:0005792)1.51737877
135Hypoventilation (HP:0002791)1.51543391
136Joint laxity (HP:0001388)1.51524698
137Distal lower limb amyotrophy (HP:0008944)1.50837438

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN4.25766189
2LATS14.01839131
3CDK123.06254611
4OBSCN3.00031040
5TRIB32.67737153
6MST1R2.50990852
7PDGFRA2.47288933
8DMPK2.46654278
9DDR22.42920081
10LATS22.35464197
11EPHB22.23889655
12PKN22.17935394
13STK38L1.98796596
14NEK11.90250673
15ERBB41.86061476
16NTRK11.84518069
17EPHA21.79390206
18ZAK1.65572052
19PIK3CA1.63882114
20STK31.50513850
21PNCK1.46037472
22PHKG21.44468704
23PHKG11.44468704
24RIPK11.43651065
25SIK11.42675330
26FER1.38969458
27MTOR1.38897021
28PTK61.38166833
29FGFR11.36446811
30PAK31.30326950
31LMTK21.29998894
32ERBB31.29268014
33PAK21.28811830
34PBK1.27968115
35PTK21.25527867
36PRKD31.07344503
37BRD41.06823065
38MYLK1.06693775
39CAMK1D1.05577808
40ROCK11.04370327
41TTK1.04281616
42ILK1.00447614
43MET0.99400881
44MOS0.97648288
45CDK60.97434275
46PDK40.96298992
47PDK30.96298992
48WEE10.96289634
49ICK0.95698714
50STK240.95218557
51CDC42BPA0.94963225
52BRSK20.94929302
53NEK90.93958234
54PAK40.93173676
55CAMK1G0.92105117
56TRPM70.90517458
57SCYL20.88835832
58NUAK10.87521559
59EPHA30.87075051
60BMX0.84397263
61MUSK0.83366624
62FLT30.82421628
63CDK80.79692779
64MKNK10.79212733
65PDGFRB0.77327778
66MAP3K100.77093858
67AKT30.75962378
68TESK10.75689817
69MARK10.75349472
70FGFR20.74964609
71WNK10.74865254
72CDC70.72232538
73PIK3CG0.71327788
74TGFBR10.67769282
75LRRK20.64198580
76ERBB20.64126681
77STK390.63498639
78RPS6KB20.62442231
79AKT20.62127021
80PLK30.61110137
81NEK20.61007816
82PRKD10.59404146
83MAP3K60.58745476
84MAP3K70.58567133
85CDK70.58201629
86EPHB10.57340776
87TSSK60.57071403
88MKNK20.56794013
89MELK0.56217337
90LIMK10.55640466
91CAMK2G0.55592479
92AURKB0.54873985
93MAP3K30.54861757
94CAMK2D0.53100007
95BRSK10.52505766
96PDK20.51760249
97DYRK1B0.50597315
98KSR10.49930077
99STK380.49638034
100MAP2K10.49511248
101CDK40.48581992
102CHEK20.48516787
103PRKAA20.47659870
104PTK2B0.46546247
105TIE10.45945799
106FRK0.45541331
107ROCK20.45055000
108WNK40.44198423
109RPS6KA40.42383462
110CHEK10.41865555
111RPS6KA20.41685218
112PRKAA10.41056514
113STK100.40805963
114EIF2AK10.39983353
115SGK30.38675783
116ABL20.38560884
117GSK3A0.38497146
118ATM0.38201560
119PLK20.37158536
120TGFBR20.36979427
121PLK10.36552348
122FGFR40.35947198
123PRKD20.34696872
124TYRO30.34415500
125STK40.34321732
126EEF2K0.34318073
127CAMK2B0.34283386
128AKT10.33833125
129INSR0.33712398
130FGFR30.33703630
131BCR0.31138892
132PRKCE0.30279240
133RET0.27649217
134MAPK100.26716996
135CDK90.26448216

Predicted pathways (KEGG)

RankGene SetZ-score
1Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.47487980
2Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054123.40483544
3Dilated cardiomyopathy_Homo sapiens_hsa054143.33266178
4ECM-receptor interaction_Homo sapiens_hsa045123.13197510
5Adherens junction_Homo sapiens_hsa045203.02140397
6Basal cell carcinoma_Homo sapiens_hsa052172.74396220
7Focal adhesion_Homo sapiens_hsa045102.62144564
8* Hippo signaling pathway_Homo sapiens_hsa043902.47639773
9Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.31238054
10Hedgehog signaling pathway_Homo sapiens_hsa043402.22421042
11Proteoglycans in cancer_Homo sapiens_hsa052052.13486302
12Tight junction_Homo sapiens_hsa045302.06697100
13TGF-beta signaling pathway_Homo sapiens_hsa043502.02329151
14MicroRNAs in cancer_Homo sapiens_hsa052061.96743641
15Viral myocarditis_Homo sapiens_hsa054161.94009669
16Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.93361995
17Small cell lung cancer_Homo sapiens_hsa052221.87815408
182-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.67497847
19Cardiac muscle contraction_Homo sapiens_hsa042601.58352044
20Wnt signaling pathway_Homo sapiens_hsa043101.51155073
21Bladder cancer_Homo sapiens_hsa052191.50656268
22Lysine degradation_Homo sapiens_hsa003101.48261329
23Protein digestion and absorption_Homo sapiens_hsa049741.42773554
24Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.37101599
25Amoebiasis_Homo sapiens_hsa051461.33144687
26Melanoma_Homo sapiens_hsa052181.31989250
27Regulation of actin cytoskeleton_Homo sapiens_hsa048101.29409301
28p53 signaling pathway_Homo sapiens_hsa041151.28238373
29Cell cycle_Homo sapiens_hsa041101.26594367
30PI3K-Akt signaling pathway_Homo sapiens_hsa041511.25380752
31Notch signaling pathway_Homo sapiens_hsa043301.22000139
32Pathways in cancer_Homo sapiens_hsa052001.21409320
33Thyroid hormone signaling pathway_Homo sapiens_hsa049191.21345985
34Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.20912634
35Prostate cancer_Homo sapiens_hsa052151.18819165
36Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.14373519
37Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.13634070
38AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.13443964
39Axon guidance_Homo sapiens_hsa043601.11582346
40Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.10415294
41AMPK signaling pathway_Homo sapiens_hsa041521.08701332
42Endometrial cancer_Homo sapiens_hsa052131.07827898
43Melanogenesis_Homo sapiens_hsa049161.07622411
44mTOR signaling pathway_Homo sapiens_hsa041501.02586216
45Leukocyte transendothelial migration_Homo sapiens_hsa046701.00977862
46Central carbon metabolism in cancer_Homo sapiens_hsa052301.00110870
47Glucagon signaling pathway_Homo sapiens_hsa049220.99671765
48Insulin resistance_Homo sapiens_hsa049310.99269136
49Chronic myeloid leukemia_Homo sapiens_hsa052200.97465842
50HTLV-I infection_Homo sapiens_hsa051660.96648388
51Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.96289297
52Longevity regulating pathway - mammal_Homo sapiens_hsa042110.93738323
53Thyroid cancer_Homo sapiens_hsa052160.93295106
54Insulin signaling pathway_Homo sapiens_hsa049100.93045643
55RNA transport_Homo sapiens_hsa030130.92968737
56mRNA surveillance pathway_Homo sapiens_hsa030150.91574171
57Rap1 signaling pathway_Homo sapiens_hsa040150.89363424
58cGMP-PKG signaling pathway_Homo sapiens_hsa040220.87268412
59Colorectal cancer_Homo sapiens_hsa052100.86552194
60Renal cell carcinoma_Homo sapiens_hsa052110.85676463
61HIF-1 signaling pathway_Homo sapiens_hsa040660.84550537
62FoxO signaling pathway_Homo sapiens_hsa040680.80129324
63Pyruvate metabolism_Homo sapiens_hsa006200.75253359
64Carbon metabolism_Homo sapiens_hsa012000.74374435
65Glioma_Homo sapiens_hsa052140.73151506
66Thyroid hormone synthesis_Homo sapiens_hsa049180.70962837
67Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.68948558
68Pentose phosphate pathway_Homo sapiens_hsa000300.65623531
69Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.64789513
70Dorso-ventral axis formation_Homo sapiens_hsa043200.63918345
71Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.63869923
72Vitamin B6 metabolism_Homo sapiens_hsa007500.62818117
73Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61991831
74Propanoate metabolism_Homo sapiens_hsa006400.61865807
75Gap junction_Homo sapiens_hsa045400.56590946
76Prion diseases_Homo sapiens_hsa050200.55901927
77Fatty acid metabolism_Homo sapiens_hsa012120.55545329
78Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.55010958
79Arginine biosynthesis_Homo sapiens_hsa002200.54923421
80Oocyte meiosis_Homo sapiens_hsa041140.54597028
81Vascular smooth muscle contraction_Homo sapiens_hsa042700.54215443
82Pancreatic cancer_Homo sapiens_hsa052120.52921778
83Fatty acid degradation_Homo sapiens_hsa000710.52195806
84Viral carcinogenesis_Homo sapiens_hsa052030.51414873
85Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.50909410
86Fatty acid biosynthesis_Homo sapiens_hsa000610.50240313
87Transcriptional misregulation in cancer_Homo sapiens_hsa052020.49807529
88Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.49725212
89Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.49421951
90Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.45804144
91Estrogen signaling pathway_Homo sapiens_hsa049150.45649601
92Inositol phosphate metabolism_Homo sapiens_hsa005620.45611883
93GnRH signaling pathway_Homo sapiens_hsa049120.44815494
94Adipocytokine signaling pathway_Homo sapiens_hsa049200.44386491
95Renin secretion_Homo sapiens_hsa049240.43507018
96Oxytocin signaling pathway_Homo sapiens_hsa049210.43439773
97Phospholipase D signaling pathway_Homo sapiens_hsa040720.42961367
98Galactose metabolism_Homo sapiens_hsa000520.41956255
99Calcium signaling pathway_Homo sapiens_hsa040200.41908774
100Starch and sucrose metabolism_Homo sapiens_hsa005000.41563684
101N-Glycan biosynthesis_Homo sapiens_hsa005100.41444104
102Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.40962782
103Circadian rhythm_Homo sapiens_hsa047100.40737657
104Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.40467769
105Bile secretion_Homo sapiens_hsa049760.38991515
106Ovarian steroidogenesis_Homo sapiens_hsa049130.38070528
107Non-homologous end-joining_Homo sapiens_hsa034500.37790670
108One carbon pool by folate_Homo sapiens_hsa006700.37711798
109Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.37677382
110Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.36536814
111MAPK signaling pathway_Homo sapiens_hsa040100.36440706
112ErbB signaling pathway_Homo sapiens_hsa040120.35475492
113Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.35306054
114Platelet activation_Homo sapiens_hsa046110.34728479
115Renin-angiotensin system_Homo sapiens_hsa046140.33488372
116Toxoplasmosis_Homo sapiens_hsa051450.33046587
117Biosynthesis of amino acids_Homo sapiens_hsa012300.32650626
118Ras signaling pathway_Homo sapiens_hsa040140.31788710
119Neurotrophin signaling pathway_Homo sapiens_hsa047220.30179283
120RNA degradation_Homo sapiens_hsa030180.29421432
121cAMP signaling pathway_Homo sapiens_hsa040240.29075931
122Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.28042535
123Non-small cell lung cancer_Homo sapiens_hsa052230.26981755

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