TEAD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1convergent extension (GO:0060026)4.55361312
2* paraxial mesoderm development (GO:0048339)4.54077186
3DNA unwinding involved in DNA replication (GO:0006268)4.35895077
4regulation of gene silencing by miRNA (GO:0060964)4.30756184
5regulation of gene silencing by RNA (GO:0060966)4.30756184
6regulation of posttranscriptional gene silencing (GO:0060147)4.30756184
7pre-miRNA processing (GO:0031054)4.21765640
8planar cell polarity pathway involved in neural tube closure (GO:0090179)3.84459121
9establishment of apical/basal cell polarity (GO:0035089)3.62975373
10regulation of cell fate specification (GO:0042659)3.60958181
11polarized epithelial cell differentiation (GO:0030859)3.59997655
12regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.59460027
13negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.59211218
14protein localization to kinetochore (GO:0034501)3.57102909
15DNA replication-dependent nucleosome organization (GO:0034723)3.55278033
16DNA replication-dependent nucleosome assembly (GO:0006335)3.55278033
17establishment of integrated proviral latency (GO:0075713)3.52606313
18mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)3.46300294
19regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.45949503
20nuclear pore organization (GO:0006999)3.45421666
21regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.44201252
22peptidyl-arginine omega-N-methylation (GO:0035247)3.41070920
23negative regulation of cell fate specification (GO:0009996)3.37852136
24branching involved in salivary gland morphogenesis (GO:0060445)3.31454480
25negative regulation of chondrocyte differentiation (GO:0032331)3.30175934
26protein complex localization (GO:0031503)3.29616873
27heterochromatin organization (GO:0070828)3.28531258
28* notochord development (GO:0030903)3.25911248
29non-canonical Wnt signaling pathway (GO:0035567)3.25105814
30nucleosome disassembly (GO:0006337)3.19791133
31protein-DNA complex disassembly (GO:0032986)3.19791133
32negative regulation of RNA splicing (GO:0033119)3.18655626
33nuclear pore complex assembly (GO:0051292)3.15735583
34regulation of hippo signaling (GO:0035330)3.12161454
35negative regulation of mRNA processing (GO:0050686)3.12039338
36regulation of sister chromatid cohesion (GO:0007063)3.11221217
37establishment or maintenance of monopolar cell polarity (GO:0061339)3.08966656
38establishment of monopolar cell polarity (GO:0061162)3.08966656
39G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.08742474
40positive regulation of catenin import into nucleus (GO:0035413)3.08195328
41mitotic nuclear envelope disassembly (GO:0007077)3.06075764
42regulation of branching involved in prostate gland morphogenesis (GO:0060687)3.03888316
43mitotic metaphase plate congression (GO:0007080)3.02632585
44sister chromatid segregation (GO:0000819)3.01986669
45outer ear morphogenesis (GO:0042473)3.01766293
46embryonic foregut morphogenesis (GO:0048617)3.01245401
47mitotic sister chromatid segregation (GO:0000070)3.00894542
48regulation of cardioblast differentiation (GO:0051890)2.99054008
49regulation of stem cell maintenance (GO:2000036)2.98887312
50establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.98879835
51histone arginine methylation (GO:0034969)2.98711929
52formation of translation preinitiation complex (GO:0001731)2.98527197
53peptidyl-arginine N-methylation (GO:0035246)2.98480707
54peptidyl-arginine methylation (GO:0018216)2.98480707
55lateral sprouting from an epithelium (GO:0060601)2.97660157
56protein localization to chromosome, centromeric region (GO:0071459)2.96506664
57gap junction assembly (GO:0016264)2.95751645
58axon extension involved in axon guidance (GO:0048846)2.94728190
59neuron projection extension involved in neuron projection guidance (GO:1902284)2.94728190
60regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901212.93658204
61positive regulation of SMAD protein import into nucleus (GO:0060391)2.91519616
62DNA strand elongation involved in DNA replication (GO:0006271)2.90851263
63lung-associated mesenchyme development (GO:0060484)2.89708062
64cell migration involved in sprouting angiogenesis (GO:0002042)2.87094246
65epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.85013681
66negative regulation of androgen receptor signaling pathway (GO:0060766)2.84538947
67nuclear envelope disassembly (GO:0051081)2.84432364
68membrane disassembly (GO:0030397)2.84432364
69adherens junction assembly (GO:0034333)2.83477383
70DNA replication initiation (GO:0006270)2.82963851
71regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.82561492
72regulation of catenin import into nucleus (GO:0035412)2.82520458
73DNA duplex unwinding (GO:0032508)2.77027764
74DNA geometric change (GO:0032392)2.76462882
75negative regulation of cell fate commitment (GO:0010454)2.76408212
76negative regulation of mRNA metabolic process (GO:1903312)2.75934432
77DNA strand elongation (GO:0022616)2.75701506
78endothelial cell morphogenesis (GO:0001886)2.75650229
79regulation of SMAD protein import into nucleus (GO:0060390)2.75557882
80establishment or maintenance of bipolar cell polarity (GO:0061245)2.74702870
81establishment or maintenance of apical/basal cell polarity (GO:0035088)2.74702870
82establishment of planar polarity (GO:0001736)2.73695682
83establishment of tissue polarity (GO:0007164)2.73695682
84bone trabecula formation (GO:0060346)2.71561373
85L-serine metabolic process (GO:0006563)2.70448056
86negative regulation of chromosome segregation (GO:0051985)2.69613209
87kinetochore organization (GO:0051383)2.67310291
88metaphase plate congression (GO:0051310)2.67193359
89cochlea morphogenesis (GO:0090103)2.66626789
90mRNA splicing, via spliceosome (GO:0000398)2.63054531
91RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.63054531
92mesenchymal cell proliferation (GO:0010463)2.62965982
93chromatin assembly (GO:0031497)2.62428738
94negative regulation of cartilage development (GO:0061037)2.61941165
95negative regulation of mitotic sister chromatid separation (GO:2000816)2.61847375
96negative regulation of mitotic sister chromatid segregation (GO:0033048)2.61847375
97negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.61847375
98negative regulation of sister chromatid segregation (GO:0033046)2.61847375
99mitotic spindle assembly checkpoint (GO:0007094)2.61782463
100viral transcription (GO:0019083)2.61558722
101proximal/distal pattern formation (GO:0009954)2.61522103
102hindlimb morphogenesis (GO:0035137)2.61119926
103RNA splicing, via transesterification reactions (GO:0000375)2.60707548
104mitotic chromosome condensation (GO:0007076)2.60431799
105negative regulation of DNA repair (GO:0045738)2.60021531
106spindle assembly checkpoint (GO:0071173)2.59942543
107cell surface receptor signaling pathway involved in heart development (GO:0061311)2.59933460
108regulation of spindle organization (GO:0090224)2.59675372
109dorsal/ventral axis specification (GO:0009950)2.59509666
110nodal signaling pathway (GO:0038092)2.59214516
111* hippo signaling (GO:0035329)2.58546062
112regulation of chromosome segregation (GO:0051983)2.57980070
113regulation of heart morphogenesis (GO:2000826)2.57441497
114establishment of viral latency (GO:0019043)2.57313145
115Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.56865115
116somatic stem cell division (GO:0048103)2.56564273
117anterior/posterior axis specification, embryo (GO:0008595)2.56225572
118regulation of mesoderm development (GO:2000380)2.55844381
119translational termination (GO:0006415)2.55744801
120folic acid-containing compound biosynthetic process (GO:0009396)2.54336843
121embryonic camera-type eye development (GO:0031076)2.54151929
122mitotic spindle checkpoint (GO:0071174)2.54117847
123chromosome condensation (GO:0030261)2.53832824
124regulation of translational fidelity (GO:0006450)2.53371424
125embryonic hindlimb morphogenesis (GO:0035116)2.52821496
126negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.52675387
127dosage compensation (GO:0007549)2.50530453
128spliceosomal tri-snRNP complex assembly (GO:0000244)2.50266217
129spindle checkpoint (GO:0031577)2.50008106
130bundle of His cell to Purkinje myocyte communication (GO:0086069)2.48605801
131epithelial cell-cell adhesion (GO:0090136)2.48444332
132cellular protein complex localization (GO:0034629)2.48185252
133kinetochore assembly (GO:0051382)2.48112150
134regulation of establishment of planar polarity (GO:0090175)2.47195840
135nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.47097999
136termination of RNA polymerase II transcription (GO:0006369)2.46423943
137generation of neurons (GO:0048699)2.46153969
138IMP biosynthetic process (GO:0006188)2.45621831
139negative regulation of embryonic development (GO:0045992)2.43322457
140cell-substrate adherens junction assembly (GO:0007045)2.42319220
141focal adhesion assembly (GO:0048041)2.42319220
142basement membrane organization (GO:0071711)2.40242315
143positive regulation of cell cycle G2/M phase transition (GO:1902751)2.39725276
144positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.39725276
145dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.38312625
146prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.37355074
147mesenchymal to epithelial transition (GO:0060231)2.36202776
148chondrocyte proliferation (GO:0035988)2.35997578
149ATP-dependent chromatin remodeling (GO:0043044)2.35757392
150atrioventricular valve morphogenesis (GO:0003181)2.34877733
151regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.34267651
152digestive tract morphogenesis (GO:0048546)2.33878740
153regulation of gastrulation (GO:0010470)2.32364072
154cell migration involved in gastrulation (GO:0042074)2.31517730
155ventricular cardiac muscle cell development (GO:0055015)2.31015661
156retina vasculature morphogenesis in camera-type eye (GO:0061299)2.29745086
157* neural tube closure (GO:0001843)2.29322178
158neural tube development (GO:0021915)2.28163809
159NLS-bearing protein import into nucleus (GO:0006607)2.27543647

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.42365793
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.20848869
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.94145309
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.42858572
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.30549512
6MYC_19079543_ChIP-ChIP_MESCs_Mouse3.02491955
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.85352510
8TP63_19390658_ChIP-ChIP_HaCaT_Human2.78987420
9ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.61453060
10MYC_19030024_ChIP-ChIP_MESCs_Mouse2.55221080
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.42035855
12KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.37375718
13KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.37375718
14KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.37375718
15XRN2_22483619_ChIP-Seq_HELA_Human2.22912412
16NELFA_20434984_ChIP-Seq_ESCs_Mouse2.17862038
17KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.16227785
18TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.16165373
19MYC_18358816_ChIP-ChIP_MESCs_Mouse2.15229031
20AR_21909140_ChIP-Seq_LNCAP_Human2.11429737
21SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.08586304
22SOX2_18555785_ChIP-Seq_MESCs_Mouse2.08290811
23HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.03356311
24WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.03262396
25MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.03247585
26POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.00158697
27CLOCK_20551151_ChIP-Seq_293T_Human1.98522777
28TCF3_18692474_ChIP-Seq_MEFs_Mouse1.96997045
29RARG_19884340_ChIP-ChIP_MEFs_Mouse1.91861502
30NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.91754979
31RBPJ_22232070_ChIP-Seq_NCS_Mouse1.89999625
32* MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.89753353
33* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.88969564
34CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.88599351
35TP63_17297297_ChIP-ChIP_HaCaT_Human1.80882273
36E2F1_21310950_ChIP-Seq_MCF-7_Human1.77817485
37ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.77612836
38MYC_22102868_ChIP-Seq_BL_Human1.77505576
39TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.74776153
40HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.74286790
41CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.73629861
42POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.70296892
43NANOG_18555785_ChIP-Seq_MESCs_Mouse1.69977668
44* PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.68735653
45EST1_17652178_ChIP-ChIP_JURKAT_Human1.65333741
46MYCN_18555785_ChIP-Seq_MESCs_Mouse1.64680997
47TTF2_22483619_ChIP-Seq_HELA_Human1.64303286
48POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.61972647
49ETS1_20019798_ChIP-Seq_JURKAT_Human1.61722052
50SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.59351205
51TCF3_18692474_ChIP-Seq_MESCs_Mouse1.58840780
52* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.57821389
53NANOG_21062744_ChIP-ChIP_HESCs_Human1.57468481
54CREB1_15753290_ChIP-ChIP_HEK293T_Human1.57055228
55STAT6_21828071_ChIP-Seq_BEAS2B_Human1.54475411
56* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.54007471
57ISL1_27105846_Chip-Seq_CPCs_Mouse1.53124140
58* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.51855425
59WT1_19549856_ChIP-ChIP_CCG9911_Human1.49432987
60SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.48666063
61SALL1_21062744_ChIP-ChIP_HESCs_Human1.47011997
62ERG_21242973_ChIP-ChIP_JURKAT_Human1.45698902
63* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.43919492
64RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.41557605
65CIITA_25753668_ChIP-Seq_RAJI_Human1.41230525
66KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.40786751
67TRIM28_21343339_ChIP-Seq_HEK293_Human1.35895342
68YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.34825487
69NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.34028875
70* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.31334356
71ZFP281_27345836_Chip-Seq_ESCs_Mouse1.28723247
72NANOG_16153702_ChIP-ChIP_HESCs_Human1.28478477
73NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.27687334
74ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.26859707
75TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.26214247
76* SOX2_16153702_ChIP-ChIP_HESCs_Human1.25801570
77THAP11_20581084_ChIP-Seq_MESCs_Mouse1.25111225
78HIF1A_21447827_ChIP-Seq_MCF-7_Human1.24975301
79SOX2_18692474_ChIP-Seq_MEFs_Mouse1.24561910
80DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.23821254
81NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.22408184
82SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.21244558
83NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.21192149
84POU5F1_16518401_ChIP-PET_MESCs_Mouse1.20712366
85KLF4_18555785_ChIP-Seq_MESCs_Mouse1.20379865
86KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.20177248
87STAT3_1855785_ChIP-Seq_MESCs_Mouse1.19863543
88GABP_19822575_ChIP-Seq_HepG2_Human1.19595198
89HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.18260050
90RACK7_27058665_Chip-Seq_MCF-7_Human1.18119947
91P300_27058665_Chip-Seq_ZR-75-30cells_Human1.17770452
92DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.17426322
93EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.17369511
94DCP1A_22483619_ChIP-Seq_HELA_Human1.16977443
95DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.14679597
96KDM5A_27292631_Chip-Seq_BREAST_Human1.14411756
97ZNF263_19887448_ChIP-Seq_K562_Human1.13826866
98GABP_17652178_ChIP-ChIP_JURKAT_Human1.13483396
99CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.13171896
100EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.12392640
101OCT4_18692474_ChIP-Seq_MEFs_Mouse1.11934525
102PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10897591
103KDM2B_26808549_Chip-Seq_K562_Human1.10793058
104SOX2_18692474_ChIP-Seq_MESCs_Mouse1.09512794
105JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.09004434
106* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.08547409
107CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.08169018
108SOX17_20123909_ChIP-Seq_XEN_Mouse1.08159225
109PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.07146030
110KAP1_27257070_Chip-Seq_ESCs_Mouse1.06142481
111POU5F1_16153702_ChIP-ChIP_HESCs_Human1.04726990
112UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.04466380
113FOXP3_21729870_ChIP-Seq_TREG_Human1.03342949
114TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.03251310
115POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.02626257
116PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.02075250
117TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.01786076
118RING1B_27294783_Chip-Seq_NPCs_Mouse1.01754026
119CHD1_26751641_Chip-Seq_LNCaP_Human1.00427782
120VDR_23849224_ChIP-Seq_CD4+_Human0.99948194
121NANOG_18692474_ChIP-Seq_MEFs_Mouse0.99816790
122GATA1_26923725_Chip-Seq_HPCs_Mouse0.99793693
123* ELK3_25401928_ChIP-Seq_HUVEC_Human0.99403337
124ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.96893970
125NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.96863632
126SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.96534438
127ESR1_15608294_ChIP-ChIP_MCF-7_Human0.95334723
128ELK1_19687146_ChIP-ChIP_HELA_Human0.93424251
129EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.93200232

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010030_abnormal_orbit_morphology4.13043295
2MP0003123_paternal_imprinting3.02926777
3MP0009053_abnormal_anal_canal2.95958991
4MP0000537_abnormal_urethra_morphology2.91885661
5MP0004957_abnormal_blastocyst_morpholog2.45533604
6MP0002254_reproductive_system_inflammat2.37352392
7MP0003111_abnormal_nucleus_morphology2.36876724
8MP0002653_abnormal_ependyma_morphology2.31594050
9MP0003077_abnormal_cell_cycle2.23072112
10MP0003122_maternal_imprinting2.22888688
11MP0000566_synostosis2.21297564
12MP0003693_abnormal_embryo_hatching2.19620954
13MP0003121_genomic_imprinting2.14131391
14MP0003705_abnormal_hypodermis_morpholog2.11737333
15MP0010094_abnormal_chromosome_stability2.08487240
16MP0003119_abnormal_digestive_system2.06210523
17MP0003283_abnormal_digestive_organ2.01301798
18MP0002249_abnormal_larynx_morphology1.97184845
19MP0003385_abnormal_body_wall1.96958382
20MP0003937_abnormal_limbs/digits/tail_de1.91283177
21MP0003890_abnormal_embryonic-extraembry1.90815620
22MP0000049_abnormal_middle_ear1.88229497
23MP0001293_anophthalmia1.85991999
24MP0008932_abnormal_embryonic_tissue1.85275452
25MP0003942_abnormal_urinary_system1.81690333
26MP0001299_abnormal_eye_distance/1.81622583
27MP0002085_abnormal_embryonic_tissue1.80645050
28MP0002084_abnormal_developmental_patter1.79321995
29MP0003941_abnormal_skin_development1.78959890
30MP0002932_abnormal_joint_morphology1.72235277
31MP0000428_abnormal_craniofacial_morphol1.71550441
32MP0004197_abnormal_fetal_growth/weight/1.71521643
33MP0008007_abnormal_cellular_replicative1.70991538
34MP0002282_abnormal_trachea_morphology1.70431728
35MP0001730_embryonic_growth_arrest1.69754112
36MP0005380_embryogenesis_phenotype1.68429640
37MP0001672_abnormal_embryogenesis/_devel1.68429640
38MP0005076_abnormal_cell_differentiation1.67964227
39MP0010352_gastrointestinal_tract_polyps1.65787135
40MP0008057_abnormal_DNA_replication1.64716936
41MP0004133_heterotaxia1.62595448
42MP0000350_abnormal_cell_proliferation1.60602810
43MP0003315_abnormal_perineum_morphology1.60061559
44MP0003115_abnormal_respiratory_system1.59811088
45MP0003567_abnormal_fetal_cardiomyocyte1.55294859
46MP0001697_abnormal_embryo_size1.54845705
47MP0005623_abnormal_meninges_morphology1.54633418
48MP0003984_embryonic_growth_retardation1.51827169
49MP0002088_abnormal_embryonic_growth/wei1.51147046
50MP0002938_white_spotting1.50379926
51MP0000579_abnormal_nail_morphology1.47680398
52MP0002111_abnormal_tail_morphology1.47414860
53MP0000534_abnormal_ureter_morphology1.45630987
54MP0005275_abnormal_skin_tensile1.43246218
55MP0009250_abnormal_appendicular_skeleto1.42199304
56MP0003935_abnormal_craniofacial_develop1.41456751
57MP0003755_abnormal_palate_morphology1.40528170
58MP0004272_abnormal_basement_membrane1.39717380
59MP0004858_abnormal_nervous_system1.37093127
60MP0002086_abnormal_extraembryonic_tissu1.36291321
61MP0004233_abnormal_muscle_weight1.34684261
62MP0000751_myopathy1.33002621
63MP0000733_abnormal_muscle_development1.32775721
64MP0008438_abnormal_cutaneous_collagen1.30516479
65MP0002697_abnormal_eye_size1.30403232
66MP0009384_cardiac_valve_regurgitation1.30178418
67MP0002092_abnormal_eye_morphology1.28063429
68MP0000432_abnormal_head_morphology1.26971615
69MP0002233_abnormal_nose_morphology1.26734757
70MP0001286_abnormal_eye_development1.26133814
71MP0002116_abnormal_craniofacial_bone1.25876970
72MP0001849_ear_inflammation1.23850152
73* MP0002080_prenatal_lethality1.21352695
74MP0008058_abnormal_DNA_repair1.20568110
75MP0006054_spinal_hemorrhage1.17019751
76MP0005508_abnormal_skeleton_morphology1.16707472
77MP0003136_yellow_coat_color1.16598150
78MP0005503_abnormal_tendon_morphology1.16495108
79MP0005248_abnormal_Harderian_gland1.15880193
80MP0003938_abnormal_ear_development1.14573537
81MP0002234_abnormal_pharynx_morphology1.13185422
82MP0003878_abnormal_ear_physiology1.12995106
83MP0005377_hearing/vestibular/ear_phenot1.12995106
84MP0000462_abnormal_digestive_system1.11234469
85MP0001879_abnormal_lymphatic_vessel1.09724593
86MP0000762_abnormal_tongue_morphology1.08755141
87* MP0003861_abnormal_nervous_system1.08541766
88MP0002114_abnormal_axial_skeleton1.08450572
89MP0009672_abnormal_birth_weight1.05650592
90MP0000516_abnormal_urinary_system1.05018078
91MP0005367_renal/urinary_system_phenotyp1.05018078
92MP0010630_abnormal_cardiac_muscle1.04229131
93MP0001346_abnormal_lacrimal_gland1.02964248
94MP0002108_abnormal_muscle_morphology1.01923872
95MP0009703_decreased_birth_body1.00671247
96MP0005187_abnormal_penis_morphology1.00147082
97MP0002925_abnormal_cardiovascular_devel0.99761375
98MP0003279_aneurysm0.99331940
99MP0008789_abnormal_olfactory_epithelium0.98691229
100MP0002109_abnormal_limb_morphology0.97813726
101MP0002796_impaired_skin_barrier0.90628370
102MP0001915_intracranial_hemorrhage0.88033758
103MP0000678_abnormal_parathyroid_gland0.87624437
104MP0002751_abnormal_autonomic_nervous0.86863441
105MP0005197_abnormal_uvea_morphology0.86619757
106MP0005257_abnormal_intraocular_pressure0.85474636
107MP0006138_congestive_heart_failure0.83231751
108MP0009278_abnormal_bone_marrow0.82590514
109MP0010368_abnormal_lymphatic_system0.81339946
110MP0002089_abnormal_postnatal_growth/wei0.81216417
111MP0001614_abnormal_blood_vessel0.80606531
112MP0006292_abnormal_olfactory_placode0.80373145
113MP0000163_abnormal_cartilage_morphology0.77830854
114MP0002081_perinatal_lethality0.77025777
115MP0000467_abnormal_esophagus_morphology0.76501561
116MP0004264_abnormal_extraembryonic_tissu0.75752764
117MP0000767_abnormal_smooth_muscle0.73292575
118MP0010307_abnormal_tumor_latency0.72997631
119MP0005023_abnormal_wound_healing0.71933832
120MP0003566_abnormal_cell_adhesion0.71580606

Predicted human phenotypes

RankGene SetZ-score
1Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.63752246
2Short 4th metacarpal (HP:0010044)3.63752246
3Premature rupture of membranes (HP:0001788)3.62835946
4Renal duplication (HP:0000075)3.58166963
5Broad metatarsal (HP:0001783)3.12935702
6Selective tooth agenesis (HP:0001592)3.12553316
7Abnormality of the 4th metacarpal (HP:0010012)3.05081481
8Rib fusion (HP:0000902)2.84118743
9Shallow orbits (HP:0000586)2.79649322
10Abnormal number of incisors (HP:0011064)2.75901835
11Protrusio acetabuli (HP:0003179)2.72990894
12Turricephaly (HP:0000262)2.68269683
13Colon cancer (HP:0003003)2.67575554
14Choanal stenosis (HP:0000452)2.65042446
15Partial duplication of thumb phalanx (HP:0009944)2.61025566
16Septo-optic dysplasia (HP:0100842)2.51791192
17Ependymoma (HP:0002888)2.45361937
18Short 5th finger (HP:0009237)2.39232954
19Increased nuchal translucency (HP:0010880)2.38668031
20Broad thumb (HP:0011304)2.33833957
21High anterior hairline (HP:0009890)2.33553169
22Broad toe (HP:0001837)2.32601511
23Medulloblastoma (HP:0002885)2.30543156
24Abnormality of dentin (HP:0010299)2.29137446
25Shawl scrotum (HP:0000049)2.28146865
26Atresia of the external auditory canal (HP:0000413)2.25375634
27Thin ribs (HP:0000883)2.25164618
28Absent radius (HP:0003974)2.24188216
29Aplasia/Hypoplasia of the 5th finger (HP:0006262)2.21960080
30Patellar aplasia (HP:0006443)2.21707090
31Arnold-Chiari malformation (HP:0002308)2.21694550
32Bronchomalacia (HP:0002780)2.21519486
33Short middle phalanx of the 5th finger (HP:0004220)2.20429075
34Missing ribs (HP:0000921)2.20374349
35Coronal craniosynostosis (HP:0004440)2.20000716
36Aplasia/Hypoplasia of the patella (HP:0006498)2.19638081
37Myelomeningocele (HP:0002475)2.16353603
38Ulnar bowing (HP:0003031)2.16307970
39Deviation of the thumb (HP:0009603)2.15417059
40Proximal placement of thumb (HP:0009623)2.13549218
41Vertebral clefting (HP:0008428)2.13202635
42Absent forearm bone (HP:0003953)2.13095108
43Aplasia involving forearm bones (HP:0009822)2.13095108
44Vitreoretinal degeneration (HP:0000655)2.10984005
45Skull defect (HP:0001362)2.10723070
46Esophageal atresia (HP:0002032)2.10165989
47Preaxial foot polydactyly (HP:0001841)2.07676509
48Supernumerary ribs (HP:0005815)2.07552185
49Cutaneous syndactyly (HP:0012725)2.07327249
50Abnormal lung lobation (HP:0002101)2.06873472
51Supernumerary spleens (HP:0009799)2.06724565
52Partial duplication of the phalanx of hand (HP:0009999)2.05429780
53Broad phalanges of the hand (HP:0009768)2.05394604
54Mesomelia (HP:0003027)2.05243743
55Aplasia involving bones of the extremities (HP:0009825)2.04349786
56Aplasia involving bones of the upper limbs (HP:0009823)2.04349786
57Aplasia of the phalanges of the hand (HP:0009802)2.04349786
58Bilateral microphthalmos (HP:0007633)2.03833479
59Pterygium (HP:0001059)2.02352543
60Synostosis of carpal bones (HP:0005048)2.02199322
61Maternal diabetes (HP:0009800)2.02179230
62Carpal synostosis (HP:0009702)2.01731515
63Aplasia/hypoplasia of the humerus (HP:0006507)2.01685040
64Anophthalmia (HP:0000528)1.99983548
65Spastic diplegia (HP:0001264)1.97662796
66Abnormality of abdominal situs (HP:0011620)1.97467617
67Abdominal situs inversus (HP:0003363)1.97467617
68Reticulocytopenia (HP:0001896)1.95914572
69Hepatoblastoma (HP:0002884)1.95173421
70Supernumerary bones of the axial skeleton (HP:0009144)1.94806974
71Cutaneous finger syndactyly (HP:0010554)1.94382306
72Broad finger (HP:0001500)1.93316519
73Duplication of thumb phalanx (HP:0009942)1.92199115
74Overriding aorta (HP:0002623)1.91982365
75Spinal rigidity (HP:0003306)1.91916889
76Aplasia/Hypoplasia of the sternum (HP:0006714)1.91863400
77Neonatal short-limb short stature (HP:0008921)1.91680796
78Nephroblastoma (Wilms tumor) (HP:0002667)1.89994949
79Hemivertebrae (HP:0002937)1.89679369
80Short humerus (HP:0005792)1.89427410
81Abnormality of the calcaneus (HP:0008364)1.89151244
82Deviation of the hallux (HP:0010051)1.89047083
83Preauricular skin tag (HP:0000384)1.89034544
84Trigonocephaly (HP:0000243)1.88988968
85Ectopic kidney (HP:0000086)1.88629487
86Vertebral fusion (HP:0002948)1.87918575
87Abnormality of the lacrimal duct (HP:0011481)1.87415041
88Astrocytoma (HP:0009592)1.87273486
89Abnormality of the astrocytes (HP:0100707)1.87273486
90Midline defect of the nose (HP:0004122)1.86346095
91Skin tags (HP:0010609)1.85783890
92Embryonal renal neoplasm (HP:0011794)1.85731158
93Asymmetry of the thorax (HP:0001555)1.85055808
94Mitral valve prolapse (HP:0001634)1.84860520
95Hyperacusis (HP:0010780)1.84175534
96Cervical subluxation (HP:0003308)1.81986656
97Right ventricular cardiomyopathy (HP:0011663)1.81971558
98Malignant gastrointestinal tract tumors (HP:0006749)1.81847633
99Gastrointestinal carcinoma (HP:0002672)1.81847633
100Genu recurvatum (HP:0002816)1.81712225
101Absent eyelashes (HP:0000561)1.81476552
102Broad phalanx (HP:0006009)1.81401588
103Diastasis recti (HP:0001540)1.81195830
104Pseudobulbar signs (HP:0002200)1.79589382
105Atrophic scars (HP:0001075)1.78184310
106Soft skin (HP:0000977)1.77618128
107Arterial tortuosity (HP:0005116)1.77555816
108Ankle contracture (HP:0006466)1.77392085
109Abnormality of the phalanges of the hallux (HP:0010057)1.77313248
110Broad long bones (HP:0005622)1.76892549
111Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.76840374
112Broad hallux (HP:0010055)1.76506719
113Short hallux (HP:0010109)1.76267850
114Bifid tongue (HP:0010297)1.76126606
115Abnormality of the distal phalanx of the thumb (HP:0009617)1.76054048
116Hallux valgus (HP:0001822)1.74610024
117Abnormality of the nasolacrimal system (HP:0000614)1.74190995
118Cortical dysplasia (HP:0002539)1.73201772
119Midface retrusion (HP:0011800)1.71580187
120Aortic dissection (HP:0002647)1.70585850
121Gastrointestinal atresia (HP:0002589)1.70444083
122Trismus (HP:0000211)1.70290105
123Disproportionate tall stature (HP:0001519)1.69977275
124Abnormality of the fetal cardiovascular system (HP:0010948)1.69916309
125Abnormal umbilical cord blood vessels (HP:0011403)1.69916309
126Single umbilical artery (HP:0001195)1.69916309
127Omphalocele (HP:0001539)1.69455713
128Vascular tortuosity (HP:0004948)1.69298627
129Neoplasm of striated muscle (HP:0009728)1.69253392
130Renovascular hypertension (HP:0100817)1.68980032
131Rectal prolapse (HP:0002035)1.68816949
132Natal tooth (HP:0000695)1.67618146
133Breast hypoplasia (HP:0003187)1.67481932
134Meckel diverticulum (HP:0002245)1.66967079
135Bowel diverticulosis (HP:0005222)1.66743940
136Short phalanx of the thumb (HP:0009660)1.65849859
137Vertebral arch anomaly (HP:0008438)1.65672834
138Absent eyebrow (HP:0002223)1.65270230
139Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.65146198
140Absent epiphyses (HP:0010577)1.65146198
141Bladder diverticulum (HP:0000015)1.65129606
142Abnormality of the ileum (HP:0001549)1.64540319
143Abnormality of the aortic arch (HP:0012303)1.63709504
144Rhabdomyosarcoma (HP:0002859)1.63553440
145Glioma (HP:0009733)1.63519595
146Hypoplastic labia majora (HP:0000059)1.63348489
147Intestinal atresia (HP:0011100)1.62856962
148Neoplasm of the pancreas (HP:0002894)1.62533188
149Wrist flexion contracture (HP:0001239)1.62437589
150Abnormality of the labia minora (HP:0012880)1.61959749
151Facial cleft (HP:0002006)1.61630634
152Broad distal phalanx of finger (HP:0009836)1.61361397
153Biconcave vertebral bodies (HP:0004586)1.60912886
154Ectopia lentis (HP:0001083)1.60008199
155Lymphangioma (HP:0100764)1.59965359
156Wide anterior fontanel (HP:0000260)1.59320868
157Blue sclerae (HP:0000592)1.58208282
158Advanced eruption of teeth (HP:0006288)1.57718487
159Calcaneovalgus deformity (HP:0001848)1.55487198
160Abnormality of the ischium (HP:0003174)1.55267973
161Aplasia/Hypoplasia of the hallux (HP:0008362)1.55104006
162Ectopic anus (HP:0004397)1.54330644
163Tracheal stenosis (HP:0002777)1.54308428
164Fragile skin (HP:0001030)1.54052020
165Anal stenosis (HP:0002025)1.54014826

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.53376183
2CDC73.28927693
3CDK123.06546699
4MAP3K102.88731588
5LATS12.59997756
6WEE12.42623218
7SMG12.41916689
8EPHB22.40787147
9NEK22.38836147
10LATS22.31386656
11MKNK12.28863812
12VRK22.20745636
13PASK2.16526522
14TTK2.11922112
15EEF2K2.03359067
16TIE11.99588894
17PAK41.95457030
18PKN21.88780493
19PDGFRA1.85831101
20CDK71.77413126
21RPS6KB21.76348887
22TGFBR11.74255696
23SRPK11.73982778
24TRIB31.72700593
25TAF11.71048123
26NTRK11.68880949
27BRD41.64909162
28NEK11.61536457
29FGFR41.60961635
30EPHA21.58735866
31TSSK61.58338452
32ICK1.54489609
33PLK11.52557000
34TLK11.49736096
35MKNK21.47375428
36STK38L1.43512473
37FGFR11.38648077
38PNCK1.36778560
39DDR21.34925147
40AURKB1.33058019
41MAP3K81.31479280
42CDK41.29088558
43ATR1.26126423
44MELK1.24467801
45MTOR1.23445773
46CHEK21.21865663
47TTN1.19843133
48PLK31.15836662
49PBK1.15732721
50PTK61.14036031
51CHEK11.12999821
52DYRK31.12461180
53KSR11.08828469
54CDK81.07126928
55CDK61.06895220
56PAK21.05530228
57RPS6KA41.04563795
58AURKA1.01789110
59STK30.98325057
60CAMK1G0.97905203
61STK100.97502078
62ERBB40.97438980
63BRSK20.97237834
64DMPK0.95377023
65TYRO30.93241582
66BMX0.92699854
67BRSK10.92427571
68MYLK0.90776935
69AKT20.88201339
70ILK0.84471166
71CDK20.83447933
72TESK20.80057762
73PLK40.79514340
74LRRK20.78048284
75ACVR1B0.77598628
76CAMK1D0.76464302
77ALK0.74730002
78ATM0.74015367
79ERBB20.72370823
80DYRK20.72107385
81MET0.71242246
82STK40.68484076
83TNIK0.67542607
84PTK20.67485546
85CDK10.65251005
86PAK10.63517339
87ERBB30.62206723
88SCYL20.60729945
89BRAF0.59122608
90LMTK20.58627543
91UHMK10.57112492
92TESK10.56914352
93ROCK20.56295794
94FGFR20.54995386
95NME10.54077266
96PRKCI0.52969536
97PRKG20.52932226
98EIF2AK10.52769289
99CDK90.52242739
100RPS6KA20.51480113
101DYRK1B0.51227945
102RIPK10.51062643
103CSNK1E0.50388772
104SIK10.48705713
105MAP2K20.48208020
106AKT30.46992144
107BCR0.46518269
108PRKD30.45477958
109MAP3K90.45468600
110AKT10.45008200
111FLT30.43008266
112KDR0.41875126
113RPS6KA10.41750044
114CDK11A0.41334894
115RPS6KC10.41321970
116RPS6KL10.41321970
117FER0.40826591
118TAOK20.40495494
119MST1R0.39857171
120MAPK150.38952414
121VRK10.38610331
122CLK10.37884399
123PRKDC0.37707580
124STK240.37619576
125PDGFRB0.37451304
126ROCK10.37417266
127YES10.36685312
128CSNK2A20.36656851
129CSNK2A10.36187808
130CDC42BPA0.34332835

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.70453219
2Spliceosome_Homo sapiens_hsa030403.52530870
3Mismatch repair_Homo sapiens_hsa034303.26234124
4Basal cell carcinoma_Homo sapiens_hsa052173.15640723
5RNA transport_Homo sapiens_hsa030133.00765763
6Cell cycle_Homo sapiens_hsa041102.94377702
7Base excision repair_Homo sapiens_hsa034102.65920825
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.46157063
9Hedgehog signaling pathway_Homo sapiens_hsa043402.44413433
10Ribosome_Homo sapiens_hsa030102.44054609
11mRNA surveillance pathway_Homo sapiens_hsa030152.42583358
12* Hippo signaling pathway_Homo sapiens_hsa043902.30494715
13One carbon pool by folate_Homo sapiens_hsa006702.27135734
14Notch signaling pathway_Homo sapiens_hsa043302.15908455
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.14230246
16Nucleotide excision repair_Homo sapiens_hsa034202.12702854
17Homologous recombination_Homo sapiens_hsa034402.02351815
18Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.92709874
19RNA polymerase_Homo sapiens_hsa030201.74805165
20MicroRNAs in cancer_Homo sapiens_hsa052061.69925882
21Adherens junction_Homo sapiens_hsa045201.63840648
22TGF-beta signaling pathway_Homo sapiens_hsa043501.63041960
23RNA degradation_Homo sapiens_hsa030181.59577367
24Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.58625087
25Fanconi anemia pathway_Homo sapiens_hsa034601.58572053
26p53 signaling pathway_Homo sapiens_hsa041151.55640956
27Bladder cancer_Homo sapiens_hsa052191.41704316
28Wnt signaling pathway_Homo sapiens_hsa043101.38047328
29Pyrimidine metabolism_Homo sapiens_hsa002401.35841527
30Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.32377650
31HTLV-I infection_Homo sapiens_hsa051661.29525179
32Small cell lung cancer_Homo sapiens_hsa052221.27452268
33Systemic lupus erythematosus_Homo sapiens_hsa053221.27242700
34Dilated cardiomyopathy_Homo sapiens_hsa054141.25871657
35Proteoglycans in cancer_Homo sapiens_hsa052051.25023037
36Proteasome_Homo sapiens_hsa030501.23293503
37Basal transcription factors_Homo sapiens_hsa030221.19702420
38Oocyte meiosis_Homo sapiens_hsa041141.16886835
39Tight junction_Homo sapiens_hsa045301.15191784
40Colorectal cancer_Homo sapiens_hsa052101.14087187
41Viral carcinogenesis_Homo sapiens_hsa052031.13702103
42Chronic myeloid leukemia_Homo sapiens_hsa052201.11050716
43Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.10607958
44Thyroid cancer_Homo sapiens_hsa052161.09461931
45Pathways in cancer_Homo sapiens_hsa052001.06811144
46Non-homologous end-joining_Homo sapiens_hsa034501.03352035
47Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.02018434
48Central carbon metabolism in cancer_Homo sapiens_hsa052300.98547636
49Epstein-Barr virus infection_Homo sapiens_hsa051690.91103758
50Transcriptional misregulation in cancer_Homo sapiens_hsa052020.90553090
51Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.87701146
52Focal adhesion_Homo sapiens_hsa045100.87291441
53Steroid biosynthesis_Homo sapiens_hsa001000.85493355
54Endometrial cancer_Homo sapiens_hsa052130.85081248
55ECM-receptor interaction_Homo sapiens_hsa045120.84840843
56Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.83434318
57Carbon metabolism_Homo sapiens_hsa012000.83397966
58Melanogenesis_Homo sapiens_hsa049160.83132497
59Melanoma_Homo sapiens_hsa052180.83015764
60Prostate cancer_Homo sapiens_hsa052150.81343781
61Pyruvate metabolism_Homo sapiens_hsa006200.80922078
62Viral myocarditis_Homo sapiens_hsa054160.80454908
63Lysine degradation_Homo sapiens_hsa003100.80422641
64Biosynthesis of amino acids_Homo sapiens_hsa012300.77679272
65mTOR signaling pathway_Homo sapiens_hsa041500.75304820
66Amoebiasis_Homo sapiens_hsa051460.70469765
67Herpes simplex infection_Homo sapiens_hsa051680.69885908
68Protein digestion and absorption_Homo sapiens_hsa049740.69550520
69Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.68423410
70Pentose phosphate pathway_Homo sapiens_hsa000300.65688748
71Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.65192883
72Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.65163449
73Alcoholism_Homo sapiens_hsa050340.65108261
74Prion diseases_Homo sapiens_hsa050200.65032522
75Vitamin B6 metabolism_Homo sapiens_hsa007500.64211100
76PI3K-Akt signaling pathway_Homo sapiens_hsa041510.64061453
77Insulin signaling pathway_Homo sapiens_hsa049100.63739658
78Galactose metabolism_Homo sapiens_hsa000520.62636289
79Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.62033751
80Folate biosynthesis_Homo sapiens_hsa007900.61561251
81Thyroid hormone signaling pathway_Homo sapiens_hsa049190.60782034
82ErbB signaling pathway_Homo sapiens_hsa040120.59405657
83Selenocompound metabolism_Homo sapiens_hsa004500.58006722
84AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.57230450
85Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.56135869
86Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54151102
87Axon guidance_Homo sapiens_hsa043600.54082833
88Non-small cell lung cancer_Homo sapiens_hsa052230.54079981
89Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.53933325
90HIF-1 signaling pathway_Homo sapiens_hsa040660.53104900
91Arginine and proline metabolism_Homo sapiens_hsa003300.52607768
92Estrogen signaling pathway_Homo sapiens_hsa049150.52445982
93Purine metabolism_Homo sapiens_hsa002300.51341096
94Rap1 signaling pathway_Homo sapiens_hsa040150.49325172
95Sulfur relay system_Homo sapiens_hsa041220.48600608
96Pancreatic cancer_Homo sapiens_hsa052120.48068534
97Glucagon signaling pathway_Homo sapiens_hsa049220.47363169
98Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.44312443
99Regulation of actin cytoskeleton_Homo sapiens_hsa048100.42996064
100Leukocyte transendothelial migration_Homo sapiens_hsa046700.40715601
101Hepatitis B_Homo sapiens_hsa051610.40054177
102Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.39614233
103Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.39356824
104Cyanoamino acid metabolism_Homo sapiens_hsa004600.38607972
105Cysteine and methionine metabolism_Homo sapiens_hsa002700.38000427
106Shigellosis_Homo sapiens_hsa051310.37921845
107Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.36949186
108Apoptosis_Homo sapiens_hsa042100.36732902
109Renal cell carcinoma_Homo sapiens_hsa052110.36097334
110Glioma_Homo sapiens_hsa052140.35079888
111Legionellosis_Homo sapiens_hsa051340.34905950
112Neurotrophin signaling pathway_Homo sapiens_hsa047220.34273986
113FoxO signaling pathway_Homo sapiens_hsa040680.33924599
114N-Glycan biosynthesis_Homo sapiens_hsa005100.32029519
115AMPK signaling pathway_Homo sapiens_hsa041520.27311324
116Antigen processing and presentation_Homo sapiens_hsa046120.26613713
117Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.24561842
118Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.24511259
119Longevity regulating pathway - mammal_Homo sapiens_hsa042110.23733453
1202-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.23402830
121Acute myeloid leukemia_Homo sapiens_hsa052210.22012352
122Gap junction_Homo sapiens_hsa045400.20624375
123VEGF signaling pathway_Homo sapiens_hsa043700.19090561
124Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.18350231

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