TEAD3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is predominantly expressed in the placenta and is involved in the transactivation of the chorionic somatomammotropin-B gene enhancer. Translation of this protein is initiated at a non-AUG (AUA) start codon. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1bone trabecula formation (GO:0060346)4.76300901
2planar cell polarity pathway involved in neural tube closure (GO:0090179)4.50089531
3desmosome organization (GO:0002934)4.48715286
4hemidesmosome assembly (GO:0031581)4.34753316
5regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)4.23150550
6protein heterotrimerization (GO:0070208)4.22620822
7skin morphogenesis (GO:0043589)4.15558091
8bundle of His cell to Purkinje myocyte communication (GO:0086069)4.03402268
9collagen fibril organization (GO:0030199)3.94912190
10paraxial mesoderm development (GO:0048339)3.82068658
11chondrocyte proliferation (GO:0035988)3.66223074
12endodermal cell differentiation (GO:0035987)3.64197466
13epithelial cell-cell adhesion (GO:0090136)3.51772012
14establishment of apical/basal cell polarity (GO:0035089)3.49051118
15convergent extension (GO:0060026)3.45347493
16G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.44033984
17cell-substrate junction assembly (GO:0007044)3.44012786
18neuron projection extension involved in neuron projection guidance (GO:1902284)3.43091969
19axon extension involved in axon guidance (GO:0048846)3.43091969
20regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.42563663
21negative regulation of fatty acid transport (GO:2000192)3.41205578
22COPI coating of Golgi vesicle (GO:0048205)3.31063245
23Golgi transport vesicle coating (GO:0048200)3.31063245
24protein retention in ER lumen (GO:0006621)3.24613024
25basement membrane organization (GO:0071711)3.24130214
26maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.22396317
27wound healing, spreading of epidermal cells (GO:0035313)3.21873715
28gap junction assembly (GO:0016264)3.21183017
29plasma membrane repair (GO:0001778)3.20689566
30outer ear morphogenesis (GO:0042473)3.19445501
31regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.18903931
32regulation of hippo signaling (GO:0035330)3.15040357
33sequestering of extracellular ligand from receptor (GO:0035581)3.09579997
34* hippo signaling (GO:0035329)3.09298858
35atrioventricular valve morphogenesis (GO:0003181)3.04089153
36cardiac myofibril assembly (GO:0055003)3.03412931
37branching involved in salivary gland morphogenesis (GO:0060445)3.01545167
38tooth mineralization (GO:0034505)2.96705678
39negative regulation of chondrocyte differentiation (GO:0032331)2.96596347
40positive regulation of fatty acid beta-oxidation (GO:0032000)2.95862556
41trabecula formation (GO:0060343)2.93887719
42endocardial cushion development (GO:0003197)2.92011458
43outflow tract septum morphogenesis (GO:0003148)2.89883431
44pattern specification involved in kidney development (GO:0061004)2.87126949
45collagen metabolic process (GO:0032963)2.83886735
46positive regulation of epithelial to mesenchymal transition (GO:0010718)2.82628910
47endothelial cell morphogenesis (GO:0001886)2.82101974
48Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.79425370
49polarized epithelial cell differentiation (GO:0030859)2.78684662
50semaphorin-plexin signaling pathway (GO:0071526)2.76726251
51establishment of monopolar cell polarity (GO:0061162)2.74434117
52establishment or maintenance of monopolar cell polarity (GO:0061339)2.74434117
53vascular endothelial growth factor signaling pathway (GO:0038084)2.73926238
54insulin-like growth factor receptor signaling pathway (GO:0048009)2.73649640
55adherens junction assembly (GO:0034333)2.72383951
56regulation of tight junction assembly (GO:2000810)2.71585618
57non-canonical Wnt signaling pathway (GO:0035567)2.71402846
58mesenchyme morphogenesis (GO:0072132)2.71323793
59muscle cell migration (GO:0014812)2.70677994
60cell proliferation involved in metanephros development (GO:0072203)2.70652247
61regulation of establishment of planar polarity (GO:0090175)2.70447910
62collagen catabolic process (GO:0030574)2.69984554
63multicellular organismal macromolecule metabolic process (GO:0044259)2.69831686
64regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.69618183
65glomerular basement membrane development (GO:0032836)2.69442776
66positive regulation of endothelial cell apoptotic process (GO:2000353)2.69215440
67dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.69166882
68cochlea morphogenesis (GO:0090103)2.66354108
69proline biosynthetic process (GO:0006561)2.65845256
70regulation of heart morphogenesis (GO:2000826)2.65674405
71craniofacial suture morphogenesis (GO:0097094)2.65136842
72renal filtration (GO:0097205)2.64501283
73mesenchymal-epithelial cell signaling (GO:0060638)2.63990947
74protein carboxylation (GO:0018214)2.62803824
75peptidyl-glutamic acid carboxylation (GO:0017187)2.62803824
76regulation of fatty acid beta-oxidation (GO:0031998)2.62403426
77cell-substrate adherens junction assembly (GO:0007045)2.62246165
78focal adhesion assembly (GO:0048041)2.62246165
79establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.61794315
80sarcomere organization (GO:0045214)2.61730908
81cell migration involved in sprouting angiogenesis (GO:0002042)2.61725925
82extracellular matrix disassembly (GO:0022617)2.61166170
83embryonic cranial skeleton morphogenesis (GO:0048701)2.59819099
84metanephric mesenchyme development (GO:0072075)2.59318032
85cell migration involved in heart development (GO:0060973)2.58835292
86fibroblast migration (GO:0010761)2.58668590
87multicellular organismal metabolic process (GO:0044236)2.58418264
88regulation of cardioblast differentiation (GO:0051890)2.58052047
89multicellular organismal catabolic process (GO:0044243)2.55395378
90anatomical structure regression (GO:0060033)2.54291791
91midgut development (GO:0007494)2.53927973
92wound healing, spreading of cells (GO:0044319)2.53609217
93endocardial cushion morphogenesis (GO:0003203)2.53242488
94notochord development (GO:0030903)2.52995107
95blood vessel endothelial cell migration (GO:0043534)2.52958190
96mesenchyme development (GO:0060485)2.52869539
97mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.51330670
98negative regulation of fibrinolysis (GO:0051918)2.49343901
99positive regulation of glycogen biosynthetic process (GO:0045725)2.48031876
100negative regulation of stem cell proliferation (GO:2000647)2.47693635
101substrate adhesion-dependent cell spreading (GO:0034446)2.47438969
102establishment of planar polarity (GO:0001736)2.47260363
103establishment of tissue polarity (GO:0007164)2.47260363
104establishment or maintenance of bipolar cell polarity (GO:0061245)2.46901820
105establishment or maintenance of apical/basal cell polarity (GO:0035088)2.46901820
106bone morphogenesis (GO:0060349)2.46185523
107cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.45573609
108embryonic camera-type eye development (GO:0031076)2.45240852
109positive regulation of fatty acid oxidation (GO:0046321)2.44543913
110negative regulation of cartilage development (GO:0061037)2.44205046
111regulation of transforming growth factor beta2 production (GO:0032909)2.42931110
112cell adhesion mediated by integrin (GO:0033627)2.42891217
113myofibril assembly (GO:0030239)2.41388225
114regulation of water loss via skin (GO:0033561)2.41248994
115cell-cell junction maintenance (GO:0045217)2.41025158
116negative regulation of embryonic development (GO:0045992)2.40962662
117lateral sprouting from an epithelium (GO:0060601)2.40829912
118positive regulation of cartilage development (GO:0061036)2.40661450
119positive regulation of blood vessel endothelial cell migration (GO:0043536)2.40507464
120embryonic skeletal joint morphogenesis (GO:0060272)2.40360804
121lung-associated mesenchyme development (GO:0060484)2.39964766
122dorsal/ventral axis specification (GO:0009950)2.39906063
123negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.39699354
124hair cycle (GO:0042633)2.39395570
125molting cycle (GO:0042303)2.39395570
126kidney mesenchyme development (GO:0072074)2.39295335
127regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901212.39293461
128extracellular matrix assembly (GO:0085029)2.38121772
129atrial septum morphogenesis (GO:0060413)2.36721514
130vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.34746578
131branching involved in mammary gland duct morphogenesis (GO:0060444)2.33729287
132positive regulation of smoothened signaling pathway (GO:0045880)2.32944185
133ventricular cardiac muscle cell development (GO:0055015)2.31987280
134anterior/posterior axis specification, embryo (GO:0008595)2.31870631
135negative regulation of keratinocyte proliferation (GO:0010839)2.31577261
136negative regulation of cell fate specification (GO:0009996)2.30080720
137extracellular fibril organization (GO:0043206)2.29179674
138embryonic foregut morphogenesis (GO:0048617)2.27407043
139cytoskeletal anchoring at plasma membrane (GO:0007016)2.26656891
140proline metabolic process (GO:0006560)2.26527673

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human8.74805382
2RARG_19884340_ChIP-ChIP_MEFs_Mouse4.05054855
3TRIM28_21343339_ChIP-Seq_HEK293_Human4.01344315
4TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.28338841
5ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.07477285
6PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.79020010
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.73432961
8CLOCK_20551151_ChIP-Seq_293T_Human2.59299852
9RXR_22158963_ChIP-Seq_LIVER_Mouse2.32175919
10PPARA_22158963_ChIP-Seq_LIVER_Mouse2.27401609
11* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.19558885
12NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.18627473
13ESR1_21235772_ChIP-Seq_MCF-7_Human2.15621485
14EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.05337029
15ESR2_21235772_ChIP-Seq_MCF-7_Human2.05190856
16RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.04061833
17LXR_22158963_ChIP-Seq_LIVER_Mouse1.97426559
18TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.96695673
19NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.94821414
20* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.87993597
21HIF1A_21447827_ChIP-Seq_MCF-7_Human1.83380594
22STAT6_21828071_ChIP-Seq_BEAS2B_Human1.81701089
23ERG_21242973_ChIP-ChIP_JURKAT_Human1.79610646
24POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.75740416
25TP53_20018659_ChIP-ChIP_R1E_Mouse1.70877964
26* RACK7_27058665_Chip-Seq_MCF-7_Human1.70572629
27CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.67948400
28ELK3_25401928_ChIP-Seq_HUVEC_Human1.67750320
29KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.67482082
30SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.66796272
31SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.66796272
32ESR1_20079471_ChIP-ChIP_T-47D_Human1.65455665
33* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.65174723
34EP300_21415370_ChIP-Seq_HL-1_Mouse1.61306008
35ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.60923028
36ZNF263_19887448_ChIP-Seq_K562_Human1.59792462
37CJUN_26792858_Chip-Seq_BT549_Human1.56877896
38TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.54571691
39SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.53912835
40P63_26484246_Chip-Seq_KERATINOCYTES_Human1.50178467
41ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.48756515
42PPAR_26484153_Chip-Seq_NCI-H1993_Human1.48729723
43* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.48069436
44ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.46982160
45ISL1_27105846_Chip-Seq_CPCs_Mouse1.46159628
46SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.44609700
47ATF3_27146783_Chip-Seq_COLON_Human1.44156037
48TBX20_22080862_ChIP-Seq_HEART_Mouse1.43098285
49TBX20_22328084_ChIP-Seq_HEART_Mouse1.43098285
50UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.40670525
51AR_21909140_ChIP-Seq_LNCAP_Human1.39015660
52CDX2_20551321_ChIP-Seq_CACO-2_Human1.38779723
53KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.37589823
54ZFP281_18757296_ChIP-ChIP_E14_Mouse1.37350409
55CTCF_27219007_Chip-Seq_Bcells_Human1.36618343
56P300_27058665_Chip-Seq_ZR-75-30cells_Human1.35701978
57UBF1/2_26484160_Chip-Seq_HMECs_Human1.35466563
58TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.34895677
59KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.30375849
60* LXR_22292898_ChIP-Seq_THP-1_Human1.28007749
61* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.27382022
62BRD4_25478319_ChIP-Seq_HGPS_Human1.25936851
63KDM2B_26808549_Chip-Seq_SUP-B15_Human1.25412645
64CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.24528745
65ZNF217_24962896_ChIP-Seq_MCF-7_Human1.23871128
66FOXO3_23340844_ChIP-Seq_DLD1_Human1.23263897
67NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.22437848
68* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.19498200
69NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.19189137
70ZFP281_27345836_Chip-Seq_ESCs_Mouse1.18566473
71SMC3_22415368_ChIP-Seq_MEFs_Mouse1.17866565
72* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.17133305
73* SOX2_20726797_ChIP-Seq_SW620_Human1.15081589
74CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.14808703
75* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.14480349
76TET1_21451524_ChIP-Seq_MESCs_Mouse1.14062273
77* RUNX1_27514584_Chip-Seq_MCF-7_Human1.13091793
78FOXM1_23109430_ChIP-Seq_U2OS_Human1.13082833
79KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.13033499
80SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.12684818
81GATA6_25053715_ChIP-Seq_YYC3_Human1.11554954
82KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.10906106
83KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.10906106
84KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.10906106
85* KDM2B_26808549_Chip-Seq_K562_Human1.10794956
86KLF5_25053715_ChIP-Seq_YYC3_Human1.10552237
87TCF4_18268006_ChIP-ChIP_LS174T_Human1.10329452
88STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.09918068
89CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.09791143
90NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.09632220
91ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.08650028
92SOX2_27498859_Chip-Seq_STOMACH_Mouse1.07834993
93NFIB_24661679_ChIP-Seq_LUNG_Mouse1.07745257
94TP53_22127205_ChIP-Seq_IMR90_Human1.06289819
95STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.05489857
96TET1_21490601_ChIP-Seq_MESCs_Mouse1.05255290
97TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05039690
98ESR1_15608294_ChIP-ChIP_MCF-7_Human1.04911566
99SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.03227292
100WT1_19549856_ChIP-ChIP_CCG9911_Human1.03223241
101GATA4_25053715_ChIP-Seq_YYC3_Human1.03158641
102KLF4_18555785_ChIP-Seq_MESCs_Mouse1.03153204
103SA1_27219007_Chip-Seq_ERYTHROID_Human1.03022538
104SMC1_22415368_ChIP-Seq_MEFs_Mouse1.01864929
105CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.01698887
106ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.01439032
107JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.01355747
108RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.01316856
109THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.01265303
110SMC4_20622854_ChIP-Seq_HELA_Human1.01202403
111TP63_19390658_ChIP-ChIP_HaCaT_Human0.98433193
112CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.98200192
113EED_16625203_ChIP-ChIP_MESCs_Mouse0.97795999
114P68_20966046_ChIP-Seq_HELA_Human0.97283902
115EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.96673341
116EGR1_19374776_ChIP-ChIP_THP-1_Human0.96475576
117SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.96458386
118* TCF3_18692474_ChIP-Seq_MEFs_Mouse0.96360121
119TP53_23651856_ChIP-Seq_MEFs_Mouse0.96137255
120* DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.96119867
121CTCF_27219007_Chip-Seq_ERYTHROID_Human0.95283954
122FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.94996229
123SALL4_18804426_ChIP-ChIP_XEN_Mouse0.94742581
124TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.94498698
125CREB1_26743006_Chip-Seq_LNCaP_Human0.94291526
126AHR_22903824_ChIP-Seq_MCF-7_Human0.92718087
127TP53_18474530_ChIP-ChIP_U2OS_Human0.92544173
128KDM2B_26808549_Chip-Seq_JURKAT_Human0.91956100
129KDM2B_26808549_Chip-Seq_DND41_Human0.90327446
130CDX2_19796622_ChIP-Seq_MESCs_Mouse0.89995699

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen4.64836051
2MP0005275_abnormal_skin_tensile4.31662550
3MP0003705_abnormal_hypodermis_morpholog4.11860838
4MP0005503_abnormal_tendon_morphology2.87130742
5MP0010030_abnormal_orbit_morphology2.82198761
6MP0003941_abnormal_skin_development2.47401359
7MP0004272_abnormal_basement_membrane2.40264201
8MP0009053_abnormal_anal_canal2.37550513
9MP0005623_abnormal_meninges_morphology2.29734782
10MP0003279_aneurysm2.26072142
11MP0002060_abnormal_skin_morphology2.24466196
12MP0000579_abnormal_nail_morphology2.16963097
13MP0003566_abnormal_cell_adhesion2.13638466
14MP0002796_impaired_skin_barrier2.03265682
15MP0009384_cardiac_valve_regurgitation1.95903499
16MP0010234_abnormal_vibrissa_follicle1.90248833
17MP0003385_abnormal_body_wall1.85382589
18MP0006054_spinal_hemorrhage1.82031530
19MP0001958_emphysema1.81116200
20MP0000566_synostosis1.79874473
21MP0000537_abnormal_urethra_morphology1.72505036
22MP0004858_abnormal_nervous_system1.71533052
23MP0005508_abnormal_skeleton_morphology1.55657238
24MP0000733_abnormal_muscle_development1.52809692
25MP0000762_abnormal_tongue_morphology1.52409007
26MP0005023_abnormal_wound_healing1.47904685
27MP0005409_darkened_coat_color1.47895020
28MP0005257_abnormal_intraocular_pressure1.46747731
29MP0000013_abnormal_adipose_tissue1.46582822
30MP0000467_abnormal_esophagus_morphology1.45360336
31MP0002234_abnormal_pharynx_morphology1.43972224
32MP0000003_abnormal_adipose_tissue1.43669896
33MP0001299_abnormal_eye_distance/1.41410441
34MP0003942_abnormal_urinary_system1.41371179
35MP0009250_abnormal_appendicular_skeleto1.40862721
36MP0005501_abnormal_skin_physiology1.40749523
37MP0002254_reproductive_system_inflammat1.37785399
38MP0010352_gastrointestinal_tract_polyps1.36487762
39MP0001243_abnormal_dermal_layer1.36478408
40MP0009780_abnormal_chondrocyte_physiolo1.34395031
41MP0003115_abnormal_respiratory_system1.32624592
42MP0005360_urolithiasis1.29334568
43MP0002098_abnormal_vibrissa_morphology1.29258913
44MP0000750_abnormal_muscle_regeneration1.28959781
45MP0002249_abnormal_larynx_morphology1.28400051
46MP0000534_abnormal_ureter_morphology1.28041749
47MP0002089_abnormal_postnatal_growth/wei1.24435464
48MP0000767_abnormal_smooth_muscle1.24149965
49MP0000428_abnormal_craniofacial_morphol1.24090024
50MP0000383_abnormal_hair_follicle1.22012521
51MP0003755_abnormal_palate_morphology1.21056995
52MP0002108_abnormal_muscle_morphology1.21012686
53MP0010368_abnormal_lymphatic_system1.20536536
54MP0000751_myopathy1.19376479
55MP0003950_abnormal_plasma_membrane1.18656115
56MP0010678_abnormal_skin_adnexa1.17347833
57MP0002896_abnormal_bone_mineralization1.16993547
58MP0002932_abnormal_joint_morphology1.16071314
59MP0003283_abnormal_digestive_organ1.15955450
60MP0002282_abnormal_trachea_morphology1.14440441
61MP0005076_abnormal_cell_differentiation1.14265035
62MP0003252_abnormal_bile_duct1.14054966
63MP0004084_abnormal_cardiac_muscle1.10625785
64MP0000377_abnormal_hair_follicle1.10044426
65MP0003091_abnormal_cell_migration1.09922510
66MP0003453_abnormal_keratinocyte_physiol1.09065783
67MP0000516_abnormal_urinary_system1.07210223
68MP0005367_renal/urinary_system_phenotyp1.07210223
69MP0004233_abnormal_muscle_weight1.04664100
70MP0010771_integument_phenotype1.02784112
71MP0000049_abnormal_middle_ear1.02316525
72MP0001216_abnormal_epidermal_layer1.02305056
73MP0003935_abnormal_craniofacial_develop1.01821013
74MP0005670_abnormal_white_adipose1.01170197
75MP0005248_abnormal_Harderian_gland1.00499402
76MP0002139_abnormal_hepatobiliary_system0.99111712
77MP0005085_abnormal_gallbladder_physiolo0.98888227
78MP0001849_ear_inflammation0.98561839
79MP0006138_congestive_heart_failure0.98345769
80MP0000163_abnormal_cartilage_morphology0.96419217
81MP0002697_abnormal_eye_size0.96079451
82MP0003937_abnormal_limbs/digits/tail_de0.96046359
83MP0000647_abnormal_sebaceous_gland0.95531908
84MP0004087_abnormal_muscle_fiber0.95032563
85MP0003567_abnormal_fetal_cardiomyocyte0.94927917
86MP0010630_abnormal_cardiac_muscle0.94822496
87MP0002111_abnormal_tail_morphology0.94193337
88MP0001542_abnormal_bone_strength0.94040222
89MP0000462_abnormal_digestive_system0.91489984
90MP0001346_abnormal_lacrimal_gland0.90507320
91MP0002115_abnormal_skeleton_extremities0.88238838
92MP0000678_abnormal_parathyroid_gland0.86943505
93MP0005330_cardiomyopathy0.86501755
94MP0002233_abnormal_nose_morphology0.85967983
95MP0005197_abnormal_uvea_morphology0.84967147
96MP0002837_dystrophic_cardiac_calcinosis0.83774391
97MP0000432_abnormal_head_morphology0.83619426
98MP0004197_abnormal_fetal_growth/weight/0.83501495
99MP0000749_muscle_degeneration0.83258349
100MP0005171_absent_coat_pigmentation0.82453954
101MP0003122_maternal_imprinting0.81670426
102MP0002116_abnormal_craniofacial_bone0.81548472
103MP0009672_abnormal_birth_weight0.81368088
104MP0005666_abnormal_adipose_tissue0.80830076
105MP0002128_abnormal_blood_circulation0.80720821
106MP0001661_extended_life_span0.78627573
107MP0003136_yellow_coat_color0.78241705
108MP0002085_abnormal_embryonic_tissue0.77974092
109MP0004264_abnormal_extraembryonic_tissu0.77513738
110MP0002109_abnormal_limb_morphology0.77320099
111MP0002925_abnormal_cardiovascular_devel0.77128060
112MP0005365_abnormal_bile_salt0.76864581
113MP0001614_abnormal_blood_vessel0.73778223
114MP0004185_abnormal_adipocyte_glucose0.72909551
115MP0005375_adipose_tissue_phenotype0.72707723
116MP0000759_abnormal_skeletal_muscle0.72135856
117MP0002295_abnormal_pulmonary_circulatio0.71738940
118MP0002092_abnormal_eye_morphology0.71507293
119MP0008775_abnormal_heart_ventricle0.71335028
120MP0001340_abnormal_eyelid_morphology0.69990415
121MP0002114_abnormal_axial_skeleton0.69778492
122MP0005369_muscle_phenotype0.69771225
123MP0001348_abnormal_lacrimal_gland0.68968646

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)6.07565790
2Premature rupture of membranes (HP:0001788)5.72376150
3Atrophic scars (HP:0001075)4.63127528
4Right ventricular cardiomyopathy (HP:0011663)4.40989003
5Shallow orbits (HP:0000586)4.38579646
6Ankle contracture (HP:0006466)3.96099827
7Broad metatarsal (HP:0001783)3.81854793
8Increased connective tissue (HP:0009025)3.76613230
9Type 1 muscle fiber predominance (HP:0003803)3.66830595
10Fragile skin (HP:0001030)3.64701036
11Aortic dissection (HP:0002647)3.55801340
12Peritonitis (HP:0002586)3.30844697
13Vascular tortuosity (HP:0004948)3.18418123
14Neonatal short-limb short stature (HP:0008921)3.10851774
15Arterial tortuosity (HP:0005116)3.00516351
16Cerebral aneurysm (HP:0004944)3.00261181
17Bladder diverticulum (HP:0000015)2.99487996
18Follicular hyperkeratosis (HP:0007502)2.92924991
19Mildly elevated creatine phosphokinase (HP:0008180)2.87209355
20Spinal rigidity (HP:0003306)2.84274764
21Mitral valve prolapse (HP:0001634)2.80877853
22Milia (HP:0001056)2.76513157
23Soft skin (HP:0000977)2.75874705
24Aortic aneurysm (HP:0004942)2.67793951
25Dilatation of the ascending aorta (HP:0005111)2.58088576
26Abnormality of dentin (HP:0010299)2.57675956
27Alopecia of scalp (HP:0002293)2.57320970
28Blue sclerae (HP:0000592)2.56798455
29Ventricular tachycardia (HP:0004756)2.53646823
30Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.51322427
31Short 4th metacarpal (HP:0010044)2.51322427
32Pterygium (HP:0001059)2.40424970
33Muscle fiber splitting (HP:0003555)2.34918147
34Abnormality of the 4th metacarpal (HP:0010012)2.34009157
35Cervical subluxation (HP:0003308)2.30410917
36Deviation of the hallux (HP:0010051)2.26552793
37Wide anterior fontanel (HP:0000260)2.24689614
38Wrist flexion contracture (HP:0001239)2.24661030
39Pili torti (HP:0003777)2.22557437
40Genu recurvatum (HP:0002816)2.19643085
41Thin ribs (HP:0000883)2.17801646
42Aneurysm (HP:0002617)2.16991115
43Natal tooth (HP:0000695)2.14254016
44Hallux valgus (HP:0001822)2.12911525
45Hyperacusis (HP:0010780)2.10098958
46Disproportionate tall stature (HP:0001519)2.09790862
47Mesomelia (HP:0003027)2.09561809
48Biconcave vertebral bodies (HP:0004586)2.08965287
49Hyporeflexia of lower limbs (HP:0002600)2.08944103
50Wormian bones (HP:0002645)2.08279626
51Abnormal delivery (HP:0001787)2.08232006
52Advanced eruption of teeth (HP:0006288)2.07510753
53Increased variability in muscle fiber diameter (HP:0003557)2.07305404
54Turricephaly (HP:0000262)2.03635146
55Onycholysis (HP:0001806)2.02138406
56Elbow flexion contracture (HP:0002987)2.01520318
57Partial duplication of the phalanx of hand (HP:0009999)2.01376937
58Mitral regurgitation (HP:0001653)2.01194607
59Coronal craniosynostosis (HP:0004440)2.01187165
60Woolly hair (HP:0002224)2.00518112
61Tarsal synostosis (HP:0008368)2.00510747
62Fragile nails (HP:0001808)1.99625622
63Asymmetry of the thorax (HP:0001555)1.99497193
64Camptodactyly of toe (HP:0001836)1.98217144
65Ulnar deviation of the wrist (HP:0003049)1.98125719
66Bowel diverticulosis (HP:0005222)1.95906457
67Scapular winging (HP:0003691)1.95209523
68Hyperextensible skin (HP:0000974)1.95036818
69Ectopia lentis (HP:0001083)1.94850945
70Thin bony cortex (HP:0002753)1.94533938
71Generalized amyotrophy (HP:0003700)1.94494613
72Distal lower limb muscle weakness (HP:0009053)1.92391040
73Sudden death (HP:0001699)1.92231699
74Aortic regurgitation (HP:0001659)1.91537330
75Partial duplication of thumb phalanx (HP:0009944)1.91442090
76Ulnar bowing (HP:0003031)1.91352616
77Difficulty climbing stairs (HP:0003551)1.91103790
78Abnormality of the calcaneus (HP:0008364)1.89198047
79Morphological abnormality of the middle ear (HP:0008609)1.89193099
80Popliteal pterygium (HP:0009756)1.87567257
81Renal duplication (HP:0000075)1.87336350
82Knee flexion contracture (HP:0006380)1.87130492
83Distal lower limb amyotrophy (HP:0008944)1.87081733
84Hip contracture (HP:0003273)1.86664517
85Aplasia of the musculature (HP:0100854)1.86247640
86Slender build (HP:0001533)1.85292792
87Flat acetabular roof (HP:0003180)1.83994527
88Bowed forearm bones (HP:0003956)1.82468202
89Bowing of the arm (HP:0006488)1.82468202
90Synostosis involving bones of the lower limbs (HP:0009138)1.82348456
91Synostosis involving bones of the feet (HP:0009140)1.82348456
92Abnormality of skeletal muscle fiber size (HP:0012084)1.81977226
93Vertebral compression fractures (HP:0002953)1.81700585
94Plantar hyperkeratosis (HP:0007556)1.81675083
95Abnormality of the distal phalanx of the thumb (HP:0009617)1.80944058
96Lymphangioma (HP:0100764)1.80943501
97Distal upper limb amyotrophy (HP:0007149)1.80656395
98Upper limb amyotrophy (HP:0009129)1.80656395
99Selective tooth agenesis (HP:0001592)1.80491960
100Calcaneovalgus deformity (HP:0001848)1.78724306
101Deep venous thrombosis (HP:0002625)1.78673412
102Abnormality of the calf musculature (HP:0001430)1.78168295
103Hypotrichosis (HP:0001006)1.77790692
104Round ear (HP:0100830)1.77666635
105Bell-shaped thorax (HP:0001591)1.77018812
106Achilles tendon contracture (HP:0001771)1.75780786
107Bronchomalacia (HP:0002780)1.75166827
108Abnormality of carpal bone ossification (HP:0006257)1.74754713
109Overgrowth (HP:0001548)1.74600954
110Breech presentation (HP:0001623)1.74247229
111Short nail (HP:0001799)1.73792153
112Subaortic stenosis (HP:0001682)1.73676335
113Abnormality of the left ventricular outflow tract (HP:0011103)1.73676335
114Abnormality of the acetabulum (HP:0003170)1.71262203
115Tibial bowing (HP:0002982)1.70413029
116Hypoplastic ischia (HP:0003175)1.70033343
117Limited hip movement (HP:0008800)1.69315109
118Myopathic facies (HP:0002058)1.69130161
119Mesangial abnormality (HP:0001966)1.68772164
120Joint laxity (HP:0001388)1.68439478
121Abnormality of the umbilical cord (HP:0010881)1.68050287
122Infantile muscular hypotonia (HP:0008947)1.66583826
123Trismus (HP:0000211)1.65947197
124Inguinal hernia (HP:0000023)1.65771717
125Stridor (HP:0010307)1.65508627
126Lipoatrophy (HP:0100578)1.65186322
127Hypoventilation (HP:0002791)1.64928230
128Cardiovascular calcification (HP:0011915)1.64377019
129Abnormal ossification of hand bones (HP:0005921)1.63938236
130Premature skin wrinkling (HP:0100678)1.61840450
131Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.61756816
132Broad toe (HP:0001837)1.61526539
133Abnormality of the peritoneum (HP:0002585)1.60800658
134Abnormality of the Achilles tendon (HP:0005109)1.59569353
135Deformed tarsal bones (HP:0008119)1.57856090
136Joint stiffness (HP:0001387)1.54816432
137Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.54674897
138Midface retrusion (HP:0011800)1.53685957

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.23224366
2TTN3.78487250
3LATS13.68553202
4PKN23.33499310
5EPHB23.03144442
6ERN12.97865206
7DDR22.83851138
8PDGFRA2.70356242
9SIK12.54927530
10EPHA22.44832382
11PTK62.30358680
12LATS22.27698739
13RIPK12.22956402
14MAP3K102.13362498
15STK38L1.96453615
16FER1.93107564
17SMG11.68357913
18BMX1.64226695
19DMPK1.62537757
20FGFR41.59504593
21EEF2K1.56226116
22PTK21.55993773
23MYLK1.52282018
24EPHA31.41714731
25NTRK11.40232654
26LIMK11.33380630
27MAP3K31.32764848
28MAP3K71.24601494
29ILK1.24502186
30STK31.24479474
31PAK21.23758185
32PIK3CA1.20322412
33MTOR1.19462556
34FGFR11.19076600
35TRPM71.19076186
36ICK1.18959957
37PAK41.18539369
38CDK121.16756304
39MST1R1.15557784
40MET1.12926729
41PAK31.10592707
42MUSK1.09526896
43FGFR21.07828701
44RPS6KB21.06790635
45LMTK21.04852098
46TIE11.04265858
47MAPK151.03033400
48LRRK21.00643467
49EPHB11.00085188
50WNK40.97493736
51CAMK1D0.95371936
52TGFBR20.92538885
53PDGFRB0.91059309
54PIK3CG0.89227944
55STK380.87515822
56NME10.86375805
57BCKDK0.86011895
58MAP2K30.82687925
59ROCK10.82518813
60ERBB20.81713702
61MAP2K20.79935835
62OBSCN0.79133218
63CDC42BPA0.77883604
64MAP3K60.77519603
65MAPKAPK30.77012830
66NEK90.75809556
67CDK60.74044045
68RPS6KA40.71834912
69TTK0.71799615
70NEK20.71131237
71AKT20.69972585
72MELK0.65272320
73PRKD30.61431147
74FLT30.60433057
75MAP2K10.59360342
76CDK80.58632092
77TGFBR10.57671273
78PRKD10.56563086
79PTK2B0.55543806
80NME20.55277574
81TAOK10.55206978
82CAMK1G0.54752541
83FRK0.52951857
84PRKG20.52574727
85TYRO30.52529470
86DYRK1B0.51285579
87IRAK30.49187911
88INSRR0.47940411
89CHUK0.47451192
90WNK10.47027414
91CAMK40.46166430
92PRKD20.45841175
93MARK20.44977868
94RPS6KC10.44703377
95RPS6KL10.44703377
96NEK10.43961304
97RPS6KA60.43360087
98MAPK110.41734782
99DAPK30.41099429
100BRAF0.40177217
101PAK10.40150993
102MAP3K80.39592186
103RPS6KA20.38638925
104ERBB30.38059822
105PBK0.37884090
106TAOK20.37706919
107ERBB40.37571000
108TESK10.37107206
109STK240.36680443
110PRKCI0.36679573
111CAMK2G0.36216105
112RET0.32855665
113AKT30.32340044
114MAPK10.32234779
115PDPK10.32138730
116ROCK20.32136609
117SRC0.31876126
118AURKB0.31722178
119FGFR30.28688419
120RPS6KA10.27709142
121ABL20.27554940
122PRKAA10.27422521
123GSK3A0.27211786
124MAPKAPK20.27112476
125PRKAA20.26537491
126CDK70.26150693
127ZAK0.26072050
128MAPK70.26071172

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.07767284
2Basal cell carcinoma_Homo sapiens_hsa052172.90891837
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.29512947
4Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.20183456
5Focal adhesion_Homo sapiens_hsa045102.16548871
6Fatty acid degradation_Homo sapiens_hsa000712.05662747
7Hedgehog signaling pathway_Homo sapiens_hsa043402.05266552
8Adherens junction_Homo sapiens_hsa045202.02022142
9* Hippo signaling pathway_Homo sapiens_hsa043901.98109483
10Protein digestion and absorption_Homo sapiens_hsa049741.92141379
11Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.89395185
12Bladder cancer_Homo sapiens_hsa052191.89246913
13Proteoglycans in cancer_Homo sapiens_hsa052051.85702927
14Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.75692482
15Dilated cardiomyopathy_Homo sapiens_hsa054141.73510466
16Lysine degradation_Homo sapiens_hsa003101.72580927
17Tryptophan metabolism_Homo sapiens_hsa003801.71688765
18Primary bile acid biosynthesis_Homo sapiens_hsa001201.64349387
19Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.61983183
20Small cell lung cancer_Homo sapiens_hsa052221.59703895
21Amoebiasis_Homo sapiens_hsa051461.57066746
222-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.55125392
23PPAR signaling pathway_Homo sapiens_hsa033201.54060732
24Notch signaling pathway_Homo sapiens_hsa043301.47677933
25Fructose and mannose metabolism_Homo sapiens_hsa000511.39603634
26TGF-beta signaling pathway_Homo sapiens_hsa043501.36301406
27Tight junction_Homo sapiens_hsa045301.35890477
28AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.30841026
29Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.28934893
30Arginine biosynthesis_Homo sapiens_hsa002201.24081448
31MicroRNAs in cancer_Homo sapiens_hsa052061.23817757
32Retinol metabolism_Homo sapiens_hsa008301.21883322
33Chemical carcinogenesis_Homo sapiens_hsa052041.21469792
34Complement and coagulation cascades_Homo sapiens_hsa046101.19449409
35Fatty acid metabolism_Homo sapiens_hsa012121.19099065
36Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.18568953
37Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.17522704
38Pentose and glucuronate interconversions_Homo sapiens_hsa000401.17505074
39Glycosaminoglycan degradation_Homo sapiens_hsa005311.16088874
40Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.14579685
41Propanoate metabolism_Homo sapiens_hsa006401.07248649
42Starch and sucrose metabolism_Homo sapiens_hsa005001.06962878
43Chronic myeloid leukemia_Homo sapiens_hsa052201.06897628
44Fat digestion and absorption_Homo sapiens_hsa049751.06280361
45Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.06206256
46Bile secretion_Homo sapiens_hsa049761.02608358
47Insulin resistance_Homo sapiens_hsa049311.01973495
48Cyanoamino acid metabolism_Homo sapiens_hsa004601.01897470
49Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.01331887
50Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.00335983
51Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.96117746
52beta-Alanine metabolism_Homo sapiens_hsa004100.95817534
53Steroid hormone biosynthesis_Homo sapiens_hsa001400.95686739
54Melanoma_Homo sapiens_hsa052180.94860462
55N-Glycan biosynthesis_Homo sapiens_hsa005100.92517872
56Caffeine metabolism_Homo sapiens_hsa002320.92273641
57PI3K-Akt signaling pathway_Homo sapiens_hsa041510.91497418
58Pentose phosphate pathway_Homo sapiens_hsa000300.91358221
59Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.90228973
60Pathways in cancer_Homo sapiens_hsa052000.88569360
61Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.87956191
62Wnt signaling pathway_Homo sapiens_hsa043100.87863343
63Histidine metabolism_Homo sapiens_hsa003400.86615363
64Phenylalanine metabolism_Homo sapiens_hsa003600.85161030
65Viral myocarditis_Homo sapiens_hsa054160.83712587
66Leukocyte transendothelial migration_Homo sapiens_hsa046700.79909342
67Endometrial cancer_Homo sapiens_hsa052130.79324092
68Arginine and proline metabolism_Homo sapiens_hsa003300.78097794
69Glutathione metabolism_Homo sapiens_hsa004800.77520223
70Other glycan degradation_Homo sapiens_hsa005110.77505566
71Vitamin digestion and absorption_Homo sapiens_hsa049770.77163970
72Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.76235396
73Central carbon metabolism in cancer_Homo sapiens_hsa052300.76219787
74Butanoate metabolism_Homo sapiens_hsa006500.76093490
75Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.75900794
76Adipocytokine signaling pathway_Homo sapiens_hsa049200.74910736
77Carbon metabolism_Homo sapiens_hsa012000.73413097
78Melanogenesis_Homo sapiens_hsa049160.73149129
79Prostate cancer_Homo sapiens_hsa052150.71878081
80Regulation of actin cytoskeleton_Homo sapiens_hsa048100.71840341
81Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.71493581
82Sphingolipid metabolism_Homo sapiens_hsa006000.70210217
83Peroxisome_Homo sapiens_hsa041460.68550626
84Thyroid hormone synthesis_Homo sapiens_hsa049180.66642619
85HTLV-I infection_Homo sapiens_hsa051660.66063369
86Pyruvate metabolism_Homo sapiens_hsa006200.63294582
87Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.62297659
88Biosynthesis of amino acids_Homo sapiens_hsa012300.61124728
89Prion diseases_Homo sapiens_hsa050200.60568378
90Steroid biosynthesis_Homo sapiens_hsa001000.58276671
91Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.57434232
92Toxoplasmosis_Homo sapiens_hsa051450.56949409
93Nitrogen metabolism_Homo sapiens_hsa009100.55954148
94Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.55711696
95cGMP-PKG signaling pathway_Homo sapiens_hsa040220.55464876
96Rap1 signaling pathway_Homo sapiens_hsa040150.55463404
97Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.55350070
98AMPK signaling pathway_Homo sapiens_hsa041520.54826401
99Tyrosine metabolism_Homo sapiens_hsa003500.54634627
100Gap junction_Homo sapiens_hsa045400.52668382
101Acute myeloid leukemia_Homo sapiens_hsa052210.52570293
102Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52200571
103Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.52131321
104Axon guidance_Homo sapiens_hsa043600.51320930
105Vascular smooth muscle contraction_Homo sapiens_hsa042700.50823682
106Pancreatic cancer_Homo sapiens_hsa052120.50756506
107Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.50550480
108TNF signaling pathway_Homo sapiens_hsa046680.50494042
109Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.50104942
110Insulin signaling pathway_Homo sapiens_hsa049100.49987906
111Selenocompound metabolism_Homo sapiens_hsa004500.49498568
112HIF-1 signaling pathway_Homo sapiens_hsa040660.48171167
113Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.47991212
114Drug metabolism - other enzymes_Homo sapiens_hsa009830.47597441
115VEGF signaling pathway_Homo sapiens_hsa043700.47342115
116Vibrio cholerae infection_Homo sapiens_hsa051100.45924927
117Vitamin B6 metabolism_Homo sapiens_hsa007500.45736978
118Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.45558955
119Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.45363722
120Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.44822684
121Glucagon signaling pathway_Homo sapiens_hsa049220.44530681
122Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.44210686
123Glioma_Homo sapiens_hsa052140.43937528
124Sulfur relay system_Homo sapiens_hsa041220.43923267
125Thyroid hormone signaling pathway_Homo sapiens_hsa049190.43395460
126Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.42953882
127GnRH signaling pathway_Homo sapiens_hsa049120.42383587
128Sulfur metabolism_Homo sapiens_hsa009200.41900345
129Ovarian steroidogenesis_Homo sapiens_hsa049130.41580934
130p53 signaling pathway_Homo sapiens_hsa041150.41566899
131Galactose metabolism_Homo sapiens_hsa000520.41261071
132Thyroid cancer_Homo sapiens_hsa052160.40428904

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