TEC

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.63349213
2antigen processing and presentation of endogenous antigen (GO:0019883)4.71807550
3regulation of interferon-beta biosynthetic process (GO:0045357)4.61731285
4neutrophil activation involved in immune response (GO:0002283)4.57834150
5positive regulation of gamma-delta T cell activation (GO:0046645)4.50124682
6regulation of B cell receptor signaling pathway (GO:0050855)4.48377315
7positive regulation of B cell differentiation (GO:0045579)4.38436666
8antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.08542787
9antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.08542787
10positive regulation by symbiont of host defense response (GO:0052509)4.07564041
11modulation by symbiont of host defense response (GO:0052031)4.07564041
12modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.07564041
13modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.07564041
14positive regulation by organism of defense response of other organism involved in symbiotic interact4.07564041
15modulation by symbiont of host immune response (GO:0052553)4.07564041
16positive regulation of interferon-alpha production (GO:0032727)3.94173617
17positive regulation of antigen processing and presentation (GO:0002579)3.86950035
18regulation of T-helper 1 cell differentiation (GO:0045625)3.84079262
19regulation of interferon-alpha production (GO:0032647)3.72641212
20regulation of B cell differentiation (GO:0045577)3.69609095
21immunoglobulin mediated immune response (GO:0016064)3.68985627
22respiratory burst (GO:0045730)3.63795267
23NIK/NF-kappaB signaling (GO:0038061)3.62860552
24neutrophil activation (GO:0042119)3.59762500
25macrophage activation involved in immune response (GO:0002281)3.58767912
26* B cell receptor signaling pathway (GO:0050853)3.54603593
27positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.53965347
28negative regulation of erythrocyte differentiation (GO:0045647)3.53278733
29positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.51966461
30granulocyte activation (GO:0036230)3.45743172
31regulation of B cell apoptotic process (GO:0002902)3.42005172
32positive regulation of granulocyte differentiation (GO:0030854)3.35688513
33negative regulation of inflammatory response to antigenic stimulus (GO:0002862)3.35457533
34regulation of interleukin-12 biosynthetic process (GO:0045075)3.34463251
35megakaryocyte development (GO:0035855)3.31838855
36regulation of dendritic cell antigen processing and presentation (GO:0002604)3.30682968
37regulation of antigen processing and presentation (GO:0002577)3.24950266
38myeloid dendritic cell activation (GO:0001773)3.24329713
39pinocytosis (GO:0006907)3.24110508
40definitive hemopoiesis (GO:0060216)3.19197930
41regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.16924484
42regulation of gamma-delta T cell differentiation (GO:0045586)3.14420038
43myeloid cell activation involved in immune response (GO:0002275)3.13755370
44mature B cell differentiation involved in immune response (GO:0002313)3.12244249
45regulation of gamma-delta T cell activation (GO:0046643)3.12071281
46natural killer cell mediated immunity (GO:0002228)3.07607791
47natural killer cell mediated cytotoxicity (GO:0042267)3.07607791
48germinal center formation (GO:0002467)3.07306485
49response to peptidoglycan (GO:0032494)3.05053435
50cellular response to zinc ion (GO:0071294)3.03427473
51positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.03374106
52myeloid dendritic cell differentiation (GO:0043011)3.02632855
53cellular response to exogenous dsRNA (GO:0071360)3.02029656
54response to muramyl dipeptide (GO:0032495)2.97372153
55CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.94670217
56positive regulation of interferon-beta production (GO:0032728)2.90986239
57leukocyte mediated cytotoxicity (GO:0001909)2.89654605
58negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.89581022
59negative regulation of cell killing (GO:0031342)2.89581022
60positive thymic T cell selection (GO:0045059)2.89334708
61regulation of alpha-beta T cell proliferation (GO:0046640)2.87029202
62B cell mediated immunity (GO:0019724)2.87000235
63neutrophil mediated immunity (GO:0002446)2.85125192
64interferon-gamma-mediated signaling pathway (GO:0060333)2.85062672
65regulation of germinal center formation (GO:0002634)2.84868198
66regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.84632348
67positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.82170530
68negative regulation of interleukin-12 production (GO:0032695)2.81644971
69positive regulation of alpha-beta T cell proliferation (GO:0046641)2.78803245
70cellular extravasation (GO:0045123)2.77114121
71positive regulation of B cell activation (GO:0050871)2.76570404
72mature B cell differentiation (GO:0002335)2.73580130
73Arp2/3 complex-mediated actin nucleation (GO:0034314)2.72782305
74positive regulation of interleukin-12 production (GO:0032735)2.72571850
75positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.72012653
76regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.71490899
77negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.70794465
78defense response to protozoan (GO:0042832)2.70752909
79regulation of granulocyte differentiation (GO:0030852)2.70332096
80regulation of T-helper cell differentiation (GO:0045622)2.70302407
81response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.69565344
82response to host immune response (GO:0052572)2.69565344
83dendritic cell differentiation (GO:0097028)2.68464188
84regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.66737865
85T-helper 1 type immune response (GO:0042088)2.65863755
86response to type I interferon (GO:0034340)2.64998679
87negative thymic T cell selection (GO:0045060)2.64983776
88regulation of B cell proliferation (GO:0030888)2.64595702
89myeloid leukocyte activation (GO:0002274)2.64130030
90leukocyte aggregation (GO:0070486)2.63600207
91dendritic cell chemotaxis (GO:0002407)2.63551569
92B cell homeostasis (GO:0001782)2.63281109
93positive regulation of natural killer cell differentiation (GO:0032825)2.63241223
94regulation of T cell tolerance induction (GO:0002664)2.63173921
95hepatocyte apoptotic process (GO:0097284)2.62006732
96detection of bacterium (GO:0016045)2.61629936
97cytokine secretion (GO:0050663)2.61240844
98detection of other organism (GO:0098543)2.60972197
99regulation of mast cell activation (GO:0033003)2.60958482
100lipopolysaccharide-mediated signaling pathway (GO:0031663)2.60714083
101type I interferon signaling pathway (GO:0060337)2.60416205
102cellular response to type I interferon (GO:0071357)2.60416205
103JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.58587783
104antigen processing and presentation via MHC class Ib (GO:0002475)2.58225073
105regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.57339939
106dendritic cell migration (GO:0036336)2.57201162
107microglial cell activation (GO:0001774)2.56809107
108negative regulation of B cell proliferation (GO:0030889)2.56343455
109response to protozoan (GO:0001562)2.55577817
110positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.55530930
111histamine secretion (GO:0001821)2.54035442
112regulation of interleukin-8 biosynthetic process (GO:0045414)2.53940996
113cytidine metabolic process (GO:0046087)2.53917948
114cytidine catabolic process (GO:0006216)2.53917948
115cytidine deamination (GO:0009972)2.53917948
116leukocyte degranulation (GO:0043299)2.53167505
117macrophage activation (GO:0042116)2.52515622
118regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.52464072
119production of molecular mediator involved in inflammatory response (GO:0002532)2.52351094
120positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.52252385
121Peyers patch development (GO:0048541)2.51494340
122mucosal-associated lymphoid tissue development (GO:0048537)2.51494340
123positive regulation of cellular amide metabolic process (GO:0034250)2.51459454
124regulation of B cell activation (GO:0050864)2.51438038
125negative regulation of granulocyte differentiation (GO:0030853)2.51335652
126positive regulation of interleukin-2 production (GO:0032743)2.51268736
127positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.50547593
128regulation of mast cell degranulation (GO:0043304)2.50526074
129mast cell activation (GO:0045576)2.49851461
130negative T cell selection (GO:0043383)2.49652130
131response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.49453253
132response to host (GO:0075136)2.49453253
133response to host defenses (GO:0052200)2.49453253
134positive regulation of macrophage differentiation (GO:0045651)2.48825795
135reactive oxygen species biosynthetic process (GO:1903409)2.48650436
136hydrogen peroxide biosynthetic process (GO:0050665)2.48028668
137regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.47493973
138I-kappaB phosphorylation (GO:0007252)2.46959941
139T cell migration (GO:0072678)2.45940184
140adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli2.45892514
141positive regulation of T-helper cell differentiation (GO:0045624)2.45480825
142regulation of interferon-beta production (GO:0032648)2.45068780
143cellular response to interferon-gamma (GO:0071346)2.44137193
144positive regulation of B cell proliferation (GO:0030890)2.42960516
145intrinsic apoptotic signaling pathway in response to oxidative stress (GO:0008631)2.41579431
146regulation of mast cell activation involved in immune response (GO:0033006)2.41449111
147positive regulation of mast cell activation (GO:0033005)2.41092757
148cellular response to ethanol (GO:0071361)2.40995785
149chaperone mediated protein folding requiring cofactor (GO:0051085)2.39592090

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.79797512
2IRF8_21731497_ChIP-ChIP_J774_Mouse4.75987402
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.87640073
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.75651528
5* IRF8_27001747_Chip-Seq_BMDM_Mouse3.63087597
6SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.53479970
7BP1_19119308_ChIP-ChIP_Hs578T_Human3.44892263
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.37064588
9* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.34372125
10NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.18967921
11EGR1_19374776_ChIP-ChIP_THP-1_Human3.07307299
12SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.90413351
13* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.80268263
14IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.74210624
15STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.58283841
16* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.58154049
17* ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.42627848
18SCL_19346495_ChIP-Seq_HPC-7_Human2.39737530
19NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.27612692
20E2F7_22180533_ChIP-Seq_HELA_Human2.26905968
21BRD4_27068464_Chip-Seq_AML-cells_Mouse2.26559237
22NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.24773046
23RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.24761818
24STAT4_19710469_ChIP-ChIP_TH1__Mouse2.24595552
25GATA1_22025678_ChIP-Seq_K562_Human2.24315839
26* SPI1_23547873_ChIP-Seq_NB4_Human2.15641931
27MYB_26560356_Chip-Seq_TH2_Human2.11002374
28VDR_21846776_ChIP-Seq_THP-1_Human2.06497308
29RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.04611170
30EGR1_23403033_ChIP-Seq_LIVER_Mouse2.00830014
31FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.00113074
32MAF_26560356_Chip-Seq_TH1_Human1.99398646
33CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.98323736
34* PPARA_22158963_ChIP-Seq_LIVER_Mouse1.95838193
35RXR_22158963_ChIP-Seq_LIVER_Mouse1.95411135
36RUNX_20019798_ChIP-Seq_JUKART_Human1.95073397
37VDR_24763502_ChIP-Seq_THP-1_Human1.92665856
38MYB_26560356_Chip-Seq_TH1_Human1.92586580
39* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.92062080
40ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.91982921
41CIITA_25753668_ChIP-Seq_RAJI_Human1.91315417
42* RUNX1_22412390_ChIP-Seq_EML_Mouse1.87131540
43MYC_22102868_ChIP-Seq_BL_Human1.76674828
44STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.73087416
45PU_27001747_Chip-Seq_BMDM_Mouse1.70614445
46E2F4_17652178_ChIP-ChIP_JURKAT_Human1.65874953
47PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.62697981
48E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.61953581
49FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.61195362
50LXR_22158963_ChIP-Seq_LIVER_Mouse1.59022163
51VDR_23849224_ChIP-Seq_CD4+_Human1.58673751
52SPI1_23127762_ChIP-Seq_K562_Human1.56189801
53UTX_26944678_Chip-Seq_JUKART_Human1.53646894
54MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.50882117
55TCF7_22412390_ChIP-Seq_EML_Mouse1.48680661
56FOXP3_21729870_ChIP-Seq_TREG_Human1.44811688
57* GATA1_19941826_ChIP-Seq_K562_Human1.44676802
58GATA2_22383799_ChIP-Seq_G1ME_Mouse1.43782260
59CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.41248013
60CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.37611015
61STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.36841629
62LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.33903911
63CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.33686391
64* GATA3_27048872_Chip-Seq_THYMUS_Human1.29765632
65TP63_17297297_ChIP-ChIP_HaCaT_Human1.28544548
66PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.25851595
67VDR_24787735_ChIP-Seq_THP-1_Human1.24689802
68* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.21795356
69EST1_17652178_ChIP-ChIP_JURKAT_Human1.21341583
70SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.21220745
71TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.20856962
72NOTCH1_21737748_ChIP-Seq_TLL_Human1.20738279
73LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.19931725
74* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.19762943
75NCOR1_26117541_ChIP-Seq_K562_Human1.19746960
76GATA1_22383799_ChIP-Seq_G1ME_Mouse1.18544055
77EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.17999113
78KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.17616780
79* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.17007748
80TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.15722201
81CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.15337245
82ELK1_19687146_ChIP-ChIP_HELA_Human1.15324507
83GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.13739355
84SRF_21415370_ChIP-Seq_HL-1_Mouse1.13001240
85GATA3_26560356_Chip-Seq_TH2_Human1.12027247
86GABP_17652178_ChIP-ChIP_JURKAT_Human1.11924415
87FOXM1_23109430_ChIP-Seq_U2OS_Human1.09709754
88TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.09402047
89CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.07675020
90VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.04949904
91PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.03249890
92GATA2_21666600_ChIP-Seq_HMVEC_Human1.03144411
93ETS1_22383799_ChIP-Seq_G1ME_Mouse1.01912636
94MAF_26560356_Chip-Seq_TH2_Human1.01668101
95* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01362862
96FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.00748403
97PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.99726681
98THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.98957338
99ERG_20887958_ChIP-Seq_HPC-7_Mouse0.98803007
100FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98086972
101NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.98070875
102HOXB4_20404135_ChIP-ChIP_EML_Mouse0.97596379
103PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.97401845
104KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.95717674
105GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.94179214
106ELF1_17652178_ChIP-ChIP_JURKAT_Human0.92703173
107GATA1_19941827_ChIP-Seq_MEL_Mouse0.92605531
108ELK3_25401928_ChIP-Seq_HUVEC_Human0.92573467
109PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.92364790
110E2F1_21310950_ChIP-Seq_MCF-7_Human0.91357060
111* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91303062
112KDM5A_27292631_Chip-Seq_BREAST_Human0.90234079
113* MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.89754771
114MYC_18555785_ChIP-Seq_MESCs_Mouse0.88965225
115PADI4_21655091_ChIP-ChIP_MCF-7_Human0.88508374
116ETS1_20019798_ChIP-Seq_JURKAT_Human0.86457306
117FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.85492940
118FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.84859327
119CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.84832212
120FOXO3_23340844_ChIP-Seq_DLD1_Human0.84292660
121BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.83956390
122CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.81049605
123* TFEB_21752829_ChIP-Seq_HELA_Human0.80394088
124KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.80199533
125PU.1_20513432_ChIP-Seq_Bcells_Mouse0.80005920
126* GATA2_19941826_ChIP-Seq_K562_Human0.76259261
127KDM2B_26808549_Chip-Seq_SUP-B15_Human0.73807556
128SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.72430662

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.49654666
2MP0003436_decreased_susceptibility_to3.03551271
3MP0000685_abnormal_immune_system2.93764159
4MP0001800_abnormal_humoral_immune2.85924345
5MP0005387_immune_system_phenotype2.82451722
6MP0001790_abnormal_immune_system2.82451722
7MP0005000_abnormal_immune_tolerance2.75855122
8MP0002419_abnormal_innate_immunity2.62021417
9MP0002452_abnormal_antigen_presenting2.61944998
10MP0009785_altered_susceptibility_to2.61369330
11MP0002148_abnormal_hypersensitivity_rea2.60138512
12MP0005671_abnormal_response_to2.59838781
13MP0008057_abnormal_DNA_replication2.58100596
14MP0005025_abnormal_response_to2.46165560
15MP0003303_peritoneal_inflammation2.43066083
16MP0002723_abnormal_immune_serum2.41174307
17MP0002420_abnormal_adaptive_immunity2.22211918
18MP0001819_abnormal_immune_cell2.21452011
19MP0002254_reproductive_system_inflammat2.20351526
20MP0006082_CNS_inflammation2.19128804
21MP0005058_abnormal_lysosome_morphology2.18501097
22MP0002166_altered_tumor_susceptibility2.08129632
23MP0001853_heart_inflammation2.05536443
24MP0003724_increased_susceptibility_to1.99956475
25MP0003191_abnormal_cellular_cholesterol1.99533977
26* MP0005464_abnormal_platelet_physiology1.99299830
27MP0009840_abnormal_foam_cell1.91470774
28MP0004510_myositis1.88814116
29MP0002405_respiratory_system_inflammati1.85685511
30MP0003806_abnormal_nucleotide_metabolis1.85171427
31MP0004947_skin_inflammation1.83110478
32MP0002398_abnormal_bone_marrow1.80239578
33MP0000716_abnormal_immune_system1.78925248
34MP0001845_abnormal_inflammatory_respons1.76043447
35MP0003300_gastrointestinal_ulcer1.71088732
36MP0005360_urolithiasis1.70117036
37MP0010155_abnormal_intestine_physiology1.68645283
38MP0000569_abnormal_digit_pigmentation1.66426032
39MP0002006_tumorigenesis1.65944396
40MP0002138_abnormal_hepatobiliary_system1.65621175
41MP0000689_abnormal_spleen_morphology1.63127548
42MP0003763_abnormal_thymus_physiology1.58490782
43MP0001873_stomach_inflammation1.55862451
44MP0008058_abnormal_DNA_repair1.54979793
45MP0002139_abnormal_hepatobiliary_system1.54085706
46MP0008469_abnormal_protein_level1.51692979
47MP0002396_abnormal_hematopoietic_system1.51610105
48MP0002722_abnormal_immune_system1.51064687
49MP0002429_abnormal_blood_cell1.48947775
50MP0001533_abnormal_skeleton_physiology1.47699462
51MP0003172_abnormal_lysosome_physiology1.44839673
52MP0005310_abnormal_salivary_gland1.39379587
53MP0008004_abnormal_stomach_pH1.35705714
54MP0010094_abnormal_chromosome_stability1.35650412
55MP0009764_decreased_sensitivity_to1.35648115
56MP0009333_abnormal_splenocyte_physiolog1.34624816
57MP0001545_abnormal_hematopoietic_system1.32735708
58MP0005397_hematopoietic_system_phenotyp1.32735708
59MP0003183_abnormal_peptide_metabolism1.31926284
60MP0000465_gastrointestinal_hemorrhage1.29023726
61MP0008007_abnormal_cellular_replicative1.24365877
62MP0005174_abnormal_tail_pigmentation1.22648792
63MP0009278_abnormal_bone_marrow1.21087653
64MP0000858_altered_metastatic_potential1.19034848
65MP0003111_abnormal_nucleus_morphology1.15073361
66MP0005365_abnormal_bile_salt1.14293316
67MP0003448_altered_tumor_morphology1.12418935
68MP0004808_abnormal_hematopoietic_stem1.11045573
69MP0003252_abnormal_bile_duct1.10644360
70MP0000609_abnormal_liver_physiology1.10392295
71MP0005085_abnormal_gallbladder_physiolo1.08936379
72MP0005220_abnormal_exocrine_pancreas1.08925364
73MP0009763_increased_sensitivity_to1.06823200
74MP0005451_abnormal_body_composition1.04728398
75MP0000343_altered_response_to1.03622519
76MP0010352_gastrointestinal_tract_polyps1.00462377
77MP0010307_abnormal_tumor_latency0.99313162
78MP0000703_abnormal_thymus_morphology0.99086469
79MP0000015_abnormal_ear_pigmentation0.96827174
80MP0003828_pulmonary_edema0.96489822
81MP0009765_abnormal_xenobiotic_induced0.96414939
82MP0002933_joint_inflammation0.94882434
83MP0010329_abnormal_lipoprotein_level0.93743214
84MP0003453_abnormal_keratinocyte_physiol0.88783058
85MP0003566_abnormal_cell_adhesion0.88297588
86MP0000604_amyloidosis0.87854728
87MP0003786_premature_aging0.87302103
88MP0003077_abnormal_cell_cycle0.86449308
89MP0000490_abnormal_crypts_of0.86294165
90MP0002998_abnormal_bone_remodeling0.85861197
91MP0008995_early_reproductive_senescence0.85437061
92MP0003075_altered_response_to0.84752602
93MP0008875_abnormal_xenobiotic_pharmacok0.84107716
94MP0001851_eye_inflammation0.82586191
95MP0002136_abnormal_kidney_physiology0.82411853
96MP0002132_abnormal_respiratory_system0.81130758
97MP0004957_abnormal_blastocyst_morpholog0.80137444
98MP0003866_abnormal_defecation0.79779673
99MP0003045_fibrosis0.79296363
100MP0000249_abnormal_blood_vessel0.77889933
101MP0000313_abnormal_cell_death0.76853796
102MP0005076_abnormal_cell_differentiation0.76684663
103MP0003656_abnormal_erythrocyte_physiolo0.76615920
104MP0005166_decreased_susceptibility_to0.74217308
105MP0000598_abnormal_liver_morphology0.73038544
106MP0006036_abnormal_mitochondrial_physio0.73002148
107MP0005647_abnormal_sex_gland0.70803295
108MP0009643_abnormal_urine_homeostasis0.70777047
109MP0001764_abnormal_homeostasis0.70656749
110MP0000371_diluted_coat_color0.69697665
111MP0002009_preneoplasia0.68204315
112MP0008260_abnormal_autophagy0.67721669
113MP0000767_abnormal_smooth_muscle0.67544140
114MP0005319_abnormal_enzyme/_coenzyme0.67429880
115MP0002019_abnormal_tumor_incidence0.66413252
116MP0009697_abnormal_copulation0.66391115
117MP0006054_spinal_hemorrhage0.65227216
118MP0005266_abnormal_metabolism0.63652523
119MP0005390_skeleton_phenotype0.62945345
120MP0005584_abnormal_enzyme/coenzyme_acti0.62575339
121MP0004185_abnormal_adipocyte_glucose0.62204679
122MP0002877_abnormal_melanocyte_morpholog0.61825159
123MP0005075_abnormal_melanosome_morpholog0.61537847
124MP0004782_abnormal_surfactant_physiolog0.60658430
125MP0002928_abnormal_bile_duct0.60546862
126MP0002693_abnormal_pancreas_physiology0.60309276
127MP0003186_abnormal_redox_activity0.59567105
128MP0005165_increased_susceptibility_to0.59427421
129MP0001663_abnormal_digestive_system0.59242375

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.99232079
2Recurrent bacterial skin infections (HP:0005406)5.90702833
3Eczematoid dermatitis (HP:0000976)5.52368718
4Recurrent gram-negative bacterial infections (HP:0005420)4.82338598
5Recurrent skin infections (HP:0001581)4.13131965
6Autoimmune hemolytic anemia (HP:0001890)4.09919663
7Recurrent fungal infections (HP:0002841)4.06609224
8Recurrent viral infections (HP:0004429)3.89195373
9Mediastinal lymphadenopathy (HP:0100721)3.74374682
10Abnormality of macrophages (HP:0004311)3.68654519
11Agammaglobulinemia (HP:0004432)3.60755594
12Cellulitis (HP:0100658)3.60590881
13Colitis (HP:0002583)3.53472680
14Vacuolated lymphocytes (HP:0001922)3.51983880
15Systemic lupus erythematosus (HP:0002725)3.50804448
16Myositis (HP:0100614)3.49300368
17Recurrent cutaneous fungal infections (HP:0011370)3.38358799
18Chronic mucocutaneous candidiasis (HP:0002728)3.38358799
19Autoimmune thrombocytopenia (HP:0001973)3.30311763
20Elevated erythrocyte sedimentation rate (HP:0003565)3.26818443
21Meningitis (HP:0001287)3.26025561
22Myocardial infarction (HP:0001658)3.20667392
23Inflammation of the large intestine (HP:0002037)3.10369331
24Vasculitis (HP:0002633)3.08965711
25Acute lymphatic leukemia (HP:0006721)3.07609713
26Periodontitis (HP:0000704)3.06455450
27Obstructive lung disease (HP:0006536)3.05606925
28Chronic obstructive pulmonary disease (HP:0006510)3.05606925
29Gingivitis (HP:0000230)3.04746053
30Pustule (HP:0200039)2.98116219
31Osteomyelitis (HP:0002754)2.96070687
32Chronic otitis media (HP:0000389)2.95188730
33Gastrointestinal inflammation (HP:0004386)2.92683202
34Orchitis (HP:0100796)2.90426496
35Gastrointestinal stroma tumor (HP:0100723)2.89909620
36Panhypogammaglobulinemia (HP:0003139)2.87922086
37Acute myeloid leukemia (HP:0004808)2.85687342
38Abnormal delayed hypersensitivity skin test (HP:0002963)2.84954271
39Spontaneous hematomas (HP:0007420)2.82051276
40Increased IgM level (HP:0003496)2.81251755
41Amaurosis fugax (HP:0100576)2.79012111
42Joint hemorrhage (HP:0005261)2.78113866
43Stomach cancer (HP:0012126)2.77512706
44Increased cerebral lipofuscin (HP:0011813)2.76518660
45Recurrent bronchitis (HP:0002837)2.74540610
46Retrobulbar optic neuritis (HP:0100654)2.74168417
47Optic neuritis (HP:0100653)2.74168417
48IgM deficiency (HP:0002850)2.73928928
49Abnormality of glycolipid metabolism (HP:0010969)2.72315531
50Abnormality of liposaccharide metabolism (HP:0010968)2.72315531
51Abnormality of glycosphingolipid metabolism (HP:0004343)2.72315531
52Gingival bleeding (HP:0000225)2.69910351
53Recurrent pneumonia (HP:0006532)2.68801707
54Pulmonary infiltrates (HP:0002113)2.65215197
55Viral hepatitis (HP:0006562)2.64775909
56Fatigue (HP:0012378)2.64612672
57Abnormality of the prostate (HP:0008775)2.61043690
58Thrombocytosis (HP:0001894)2.59234812
59Dysostosis multiplex (HP:0000943)2.59225225
60Increased neuronal autofluorescent lipopigment (HP:0002074)2.58707803
61Glomerulonephritis (HP:0000099)2.56658459
62Arterial thrombosis (HP:0004420)2.51944810
63Urticaria (HP:0001025)2.47256763
64Axonal loss (HP:0003447)2.44451950
65Epistaxis (HP:0000421)2.43829571
66Eosinophilia (HP:0001880)2.42415910
67Hematochezia (HP:0002573)2.41614737
68Recurrent lower respiratory tract infections (HP:0002783)2.40076857
69Abnormality of the heme biosynthetic pathway (HP:0010472)2.39112771
70Petechiae (HP:0000967)2.38983717
71Leukocytosis (HP:0001974)2.38877701
72Thyroiditis (HP:0100646)2.38856865
73Abnormality of T cell number (HP:0011839)2.37478596
74Impaired platelet aggregation (HP:0003540)2.34526358
75Abnormal platelet function (HP:0011869)2.34526358
76Lymphopenia (HP:0001888)2.33405864
77Complement deficiency (HP:0004431)2.33375865
78Prostate neoplasm (HP:0100787)2.30770146
79Interstitial pulmonary disease (HP:0006530)2.30759649
80Abnormality of cells of the lymphoid lineage (HP:0012140)2.30046050
81Abnormality of complement system (HP:0005339)2.30002366
82Abnormality of T cell physiology (HP:0011840)2.29770725
83Encephalitis (HP:0002383)2.27057424
84Recurrent sinusitis (HP:0011108)2.27004861
85Stomatitis (HP:0010280)2.26730450
86Chest pain (HP:0100749)2.26711489
87Abnormality of T cells (HP:0002843)2.26204804
88T lymphocytopenia (HP:0005403)2.25514029
89Granulocytopenia (HP:0001913)2.20536007
90Chronic diarrhea (HP:0002028)2.20346261
91Purpura (HP:0000979)2.18659082
92Prolonged bleeding time (HP:0003010)2.18182908
93Sepsis (HP:0100806)2.17491164
94Abnormality of male internal genitalia (HP:0000022)2.17457028
95Increased IgE level (HP:0003212)2.16089218
96Urinary glycosaminoglycan excretion (HP:0003541)2.13923520
97Mucopolysacchariduria (HP:0008155)2.13923520
98Acute hepatic failure (HP:0006554)2.13572576
99Tetraparesis (HP:0002273)2.13284790
100Aplasia/Hypoplasia of the thymus (HP:0010515)2.12051662
101Papilloma (HP:0012740)2.11507128
102Keratoconjunctivitis (HP:0001096)2.10686976
103Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.09858153
104Lymphoma (HP:0002665)2.08286740
105Disinhibition (HP:0000734)2.06273575
106Emphysema (HP:0002097)2.05821523
107Abnormality of eosinophils (HP:0001879)2.05590002
108Hemoptysis (HP:0002105)2.04909120
109IgG deficiency (HP:0004315)2.04553834
110Abnormality of polysaccharide metabolism (HP:0011012)2.03619671
111Abnormality of glycosaminoglycan metabolism (HP:0004371)2.03619671
112Abnormality of mucopolysaccharide metabolism (HP:0011020)2.03619671
113Thick nail (HP:0001805)2.03457382
114Skin ulcer (HP:0200042)2.03049527
115Keratoconjunctivitis sicca (HP:0001097)2.02962948
116Osteolytic defects of the hand bones (HP:0009699)2.00675993
117Osteolytic defects of the phalanges of the hand (HP:0009771)2.00675993
118Hypergammaglobulinemia (HP:0010702)1.99055275
119IgA deficiency (HP:0002720)1.98399248
120Skin rash (HP:0000988)1.95875332
121Abnormality of B cell number (HP:0010975)1.95288162
122B lymphocytopenia (HP:0010976)1.95288162
123Verrucae (HP:0200043)1.94967188
124Myelodysplasia (HP:0002863)1.93315027
125Neutropenia (HP:0001875)1.92033909
126Abnormality of the vasculature of the conjunctiva (HP:0008054)1.92016604
127Abnormality of lateral ventricle (HP:0030047)1.91466822
128Basal cell carcinoma (HP:0002671)1.91100845
129Increased serum ferritin (HP:0003281)1.91087725
130Polygenic inheritance (HP:0010982)1.90890024
131Hepatosplenomegaly (HP:0001433)1.90598448
132Loss of speech (HP:0002371)1.88333804
133Albinism (HP:0001022)1.88117855

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.82054506
2MAP3K143.50147382
3TYK22.96591902
4IRAK42.72112980
5TBK12.67553081
6KIT2.62417968
7BLK2.60634784
8IRAK32.55527533
9ERN12.31008846
10TAOK32.26307530
11RIPK42.23950128
12TGFBR22.15414276
13IKBKB2.05935794
14JAK12.00241614
15CSF1R1.98134410
16IKBKE1.97217810
17SYK1.90551463
18TXK1.90196316
19JAK31.87393869
20PRPF4B1.86130388
21STK101.85705337
22* BTK1.83670257
23BRSK21.79120913
24ZAP701.70326435
25PIM21.66784117
26FLT31.50886817
27GRK61.49215491
28NEK91.49121030
29MAP2K31.46747957
30* ITK1.46588595
31FRK1.46431499
32STK241.41024380
33SIK31.39989394
34CHUK1.38330717
35PIM11.36251029
36MST41.33642464
37MAP3K131.32974089
38LYN1.32681110
39FGFR41.31295998
40* TEC1.31013796
41LRRK21.28480771
42CSK1.24116117
43* HCK1.20023396
44LCK1.17328571
45MKNK11.15605873
46EPHB11.14003100
47MAP3K31.12068484
48PTK61.11200623
49CDK121.09148661
50CCNB11.06955382
51JAK21.06017770
52RPS6KA41.05631867
53NLK1.04655846
54MAP3K101.03490676
55TNK21.02840561
56RPS6KB20.94928173
57PLK40.93301905
58STK40.88529545
59PIK3CG0.86413152
60FES0.85596171
61FGFR30.85329463
62TGFBR10.82087328
63SIK20.81553081
64MATK0.81427554
65ACVR1B0.80861669
66CDK60.77223023
67NUAK10.76665072
68MARK30.75977423
69STK160.75319757
70PKN20.74746235
71DYRK1B0.73477382
72STK30.73452758
73NME20.73091088
74EPHA30.72929965
75MAPKAPK30.71391146
76SCYL20.70977979
77IRAK20.70009571
78PRKCQ0.69562478
79TAOK20.68732318
80TRPM70.68590648
81TTN0.67083714
82MKNK20.64011529
83CAMK1D0.63752434
84EIF2AK30.61871393
85ERBB30.57464974
86ABL10.56815791
87GRK70.55109826
88CLK10.55090757
89MAP3K110.53675246
90MAPKAPK20.52842303
91PRKCD0.52132743
92CDK90.51826935
93EGFR0.51734573
94MAPK110.51675721
95ZAK0.50515873
96PRKAA20.49911034
97CDC70.49823508
98EEF2K0.48988492
99RAF10.47794724
100MAP3K10.47596702
101PBK0.47519847
102EIF2AK20.45623846
103EIF2AK10.45522291
104RPS6KA60.44851106
105MAP3K50.44465887
106BMPR20.42975629
107KDR0.42017467
108PDK10.41761008
109DAPK20.40161187
110SIK10.38406872
111TRIB30.38031707
112RPS6KC10.36901482
113RPS6KL10.36901482
114FGR0.36890874
115MAPK30.36794796
116MAPK40.36358801
117MAPK70.36112420
118CDK40.35571064
119MAPKAPK50.33992430
120ATR0.33560031
121BRD40.32480144
122MAPK150.31043558
123MAP2K20.30249285
124CHEK20.29694855
125INSRR0.29199771
126HIPK20.29076055
127BMPR1B0.28315989
128MAP3K70.27633988
129IRAK10.27456636
130MAP3K80.27326447
131* IGF1R0.25997423
132YES10.25948146
133MAPK120.25610941

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051503.02132222
2Primary immunodeficiency_Homo sapiens_hsa053402.89507967
3Leishmaniasis_Homo sapiens_hsa051402.86158231
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.68423368
5B cell receptor signaling pathway_Homo sapiens_hsa046622.61136153
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.45709143
7* Osteoclast differentiation_Homo sapiens_hsa043802.31713445
8Toll-like receptor signaling pathway_Homo sapiens_hsa046202.14189062
9Antigen processing and presentation_Homo sapiens_hsa046122.02911754
10Measles_Homo sapiens_hsa051621.95017411
11Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.90561405
12Caffeine metabolism_Homo sapiens_hsa002321.89383086
13Legionellosis_Homo sapiens_hsa051341.79184265
14Complement and coagulation cascades_Homo sapiens_hsa046101.78931284
15Hematopoietic cell lineage_Homo sapiens_hsa046401.78468322
16Allograft rejection_Homo sapiens_hsa053301.76678310
17Pertussis_Homo sapiens_hsa051331.76486940
18RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.75131624
19Graft-versus-host disease_Homo sapiens_hsa053321.74014566
20NOD-like receptor signaling pathway_Homo sapiens_hsa046211.71348539
21Tuberculosis_Homo sapiens_hsa051521.71123037
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.66534863
23Lysosome_Homo sapiens_hsa041421.58191064
24Glycosaminoglycan degradation_Homo sapiens_hsa005311.54874710
25Toxoplasmosis_Homo sapiens_hsa051451.53498179
26Other glycan degradation_Homo sapiens_hsa005111.50341766
27Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.48358992
28Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.45021488
29Pentose and glucuronate interconversions_Homo sapiens_hsa000401.44743364
30Apoptosis_Homo sapiens_hsa042101.43252455
31Influenza A_Homo sapiens_hsa051641.42955993
32Primary bile acid biosynthesis_Homo sapiens_hsa001201.39553025
33Herpes simplex infection_Homo sapiens_hsa051681.38987378
34Jak-STAT signaling pathway_Homo sapiens_hsa046301.37833852
35Malaria_Homo sapiens_hsa051441.33884972
36Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.30461501
37Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.19974328
38Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.18816275
39TNF signaling pathway_Homo sapiens_hsa046681.18743542
40Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.16734744
41Asthma_Homo sapiens_hsa053101.08285123
42Chemokine signaling pathway_Homo sapiens_hsa040621.05793195
43Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.03406261
44Hepatitis B_Homo sapiens_hsa051611.01004132
45Homologous recombination_Homo sapiens_hsa034401.00973163
46Mismatch repair_Homo sapiens_hsa034300.97142076
47Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.96262590
48Leukocyte transendothelial migration_Homo sapiens_hsa046700.95964788
49* T cell receptor signaling pathway_Homo sapiens_hsa046600.95587407
50Rheumatoid arthritis_Homo sapiens_hsa053230.94621124
51ABC transporters_Homo sapiens_hsa020100.92589589
52Viral myocarditis_Homo sapiens_hsa054160.90525670
53DNA replication_Homo sapiens_hsa030300.90476849
54Histidine metabolism_Homo sapiens_hsa003400.90362341
55Phagosome_Homo sapiens_hsa041450.90013428
56Acute myeloid leukemia_Homo sapiens_hsa052210.89054914
57Shigellosis_Homo sapiens_hsa051310.87494389
58Salmonella infection_Homo sapiens_hsa051320.85988964
59SNARE interactions in vesicular transport_Homo sapiens_hsa041300.84336543
60Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.84290043
61Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.83609368
62Hepatitis C_Homo sapiens_hsa051600.83469747
63Tryptophan metabolism_Homo sapiens_hsa003800.82658622
64Arginine biosynthesis_Homo sapiens_hsa002200.81776361
65Drug metabolism - other enzymes_Homo sapiens_hsa009830.80971467
66Chronic myeloid leukemia_Homo sapiens_hsa052200.79146263
67Transcriptional misregulation in cancer_Homo sapiens_hsa052020.77804841
68African trypanosomiasis_Homo sapiens_hsa051430.75487917
69Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.71599231
70Base excision repair_Homo sapiens_hsa034100.71126397
71Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.70137407
72Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.68039875
73Nitrogen metabolism_Homo sapiens_hsa009100.67633684
74Pancreatic cancer_Homo sapiens_hsa052120.66718692
75Autoimmune thyroid disease_Homo sapiens_hsa053200.65594396
76Starch and sucrose metabolism_Homo sapiens_hsa005000.64252267
77HTLV-I infection_Homo sapiens_hsa051660.62032219
78Platelet activation_Homo sapiens_hsa046110.61472132
79Peroxisome_Homo sapiens_hsa041460.60273315
80Fatty acid degradation_Homo sapiens_hsa000710.60200043
81Type I diabetes mellitus_Homo sapiens_hsa049400.59648070
82Retinol metabolism_Homo sapiens_hsa008300.57662687
83Small cell lung cancer_Homo sapiens_hsa052220.56604554
84PPAR signaling pathway_Homo sapiens_hsa033200.56204674
85AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.55930691
86Epstein-Barr virus infection_Homo sapiens_hsa051690.54129221
87Non-small cell lung cancer_Homo sapiens_hsa052230.53982280
88Dorso-ventral axis formation_Homo sapiens_hsa043200.51988016
89Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.51429437
90Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51184252
91Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.51122657
92Viral carcinogenesis_Homo sapiens_hsa052030.49625040
93Spliceosome_Homo sapiens_hsa030400.49324855
94Adipocytokine signaling pathway_Homo sapiens_hsa049200.49292944
95Chemical carcinogenesis_Homo sapiens_hsa052040.48886781
96Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.47445881
97Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.46698749
98Renin-angiotensin system_Homo sapiens_hsa046140.46494817
99Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.46304258
100Insulin resistance_Homo sapiens_hsa049310.46287931
101Lysine degradation_Homo sapiens_hsa003100.45800682
102Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.45726891
103p53 signaling pathway_Homo sapiens_hsa041150.45558658
104Proteasome_Homo sapiens_hsa030500.44708658
105Non-homologous end-joining_Homo sapiens_hsa034500.44293519
106Selenocompound metabolism_Homo sapiens_hsa004500.43954949
107Prolactin signaling pathway_Homo sapiens_hsa049170.43641929
108Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.43092189
109Steroid hormone biosynthesis_Homo sapiens_hsa001400.42279522
110RNA degradation_Homo sapiens_hsa030180.42244090
111Nucleotide excision repair_Homo sapiens_hsa034200.42136572
112Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.41678746
113Vitamin digestion and absorption_Homo sapiens_hsa049770.41518011
114Systemic lupus erythematosus_Homo sapiens_hsa053220.40857955
115Pentose phosphate pathway_Homo sapiens_hsa000300.39920344
116Fanconi anemia pathway_Homo sapiens_hsa034600.39837038
117beta-Alanine metabolism_Homo sapiens_hsa004100.38926323
118Amoebiasis_Homo sapiens_hsa051460.38439663
119One carbon pool by folate_Homo sapiens_hsa006700.37434552
120RNA transport_Homo sapiens_hsa030130.33670830
121Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.31119002
122Sphingolipid signaling pathway_Homo sapiens_hsa040710.28710549
123Bladder cancer_Homo sapiens_hsa052190.28034056
124Sphingolipid metabolism_Homo sapiens_hsa006000.26859627
125Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.26313959
126Neurotrophin signaling pathway_Homo sapiens_hsa047220.24796179
127Type II diabetes mellitus_Homo sapiens_hsa049300.23669730
128Sulfur metabolism_Homo sapiens_hsa009200.23525355
129Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.21742428
130Phosphatidylinositol signaling system_Homo sapiens_hsa040700.21677783
131HIF-1 signaling pathway_Homo sapiens_hsa040660.20600378
132Prostate cancer_Homo sapiens_hsa052150.20156568
133Cell cycle_Homo sapiens_hsa041100.19231407
134Ribosome_Homo sapiens_hsa030100.18672188

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