TECPR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a tethering factor involved in autophagy. The encoded protein is found at autolysosomes, and is involved in targeting protein aggregates, damaged mitochondria, and bacterial pathogens for autophagy NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1melanin biosynthetic process (GO:0042438)5.97032985
2melanin metabolic process (GO:0006582)5.82126194
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.31181767
4negative regulation of cell killing (GO:0031342)5.31181767
5antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.97451762
6antigen processing and presentation of endogenous antigen (GO:0019883)4.78848408
7secondary metabolite biosynthetic process (GO:0044550)4.77273562
8developmental pigmentation (GO:0048066)4.60441387
9positive regulation of gamma-delta T cell activation (GO:0046645)4.55016851
10antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.52494016
11negative regulation of erythrocyte differentiation (GO:0045647)3.82012892
12detection of other organism (GO:0098543)3.66959458
13negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.62421099
14detection of bacterium (GO:0016045)3.61370095
15positive thymic T cell selection (GO:0045059)3.60074776
16positive T cell selection (GO:0043368)3.57855219
17negative T cell selection (GO:0043383)3.49731900
18negative thymic T cell selection (GO:0045060)3.42704628
19mannose metabolic process (GO:0006013)3.39136412
20negative regulation of leukocyte mediated immunity (GO:0002704)3.37369438
21macrophage activation involved in immune response (GO:0002281)3.31926027
22positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.27713056
23cellular potassium ion homeostasis (GO:0030007)3.27687383
24regulation of gamma-delta T cell activation (GO:0046643)3.25688608
25regulation of gamma-delta T cell differentiation (GO:0045586)3.23097552
26regulation of B cell receptor signaling pathway (GO:0050855)3.16630126
27T cell selection (GO:0045058)3.15399172
28cerebellar Purkinje cell differentiation (GO:0021702)3.15285251
29thymic T cell selection (GO:0045061)3.13140647
30cellular extravasation (GO:0045123)3.11926702
31positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.11626654
32regulation of ARF protein signal transduction (GO:0032012)3.04548812
33synaptic vesicle maturation (GO:0016188)3.00467437
34regulation of short-term neuronal synaptic plasticity (GO:0048172)3.00283101
35ionotropic glutamate receptor signaling pathway (GO:0035235)2.97851661
36neuronal action potential propagation (GO:0019227)2.97731819
37antigen processing and presentation via MHC class Ib (GO:0002475)2.94655511
38interferon-gamma production (GO:0032609)2.91749536
39signal complex assembly (GO:0007172)2.89971108
40activated T cell proliferation (GO:0050798)2.89410053
41detection of external biotic stimulus (GO:0098581)2.88837564
42positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.87521724
43sodium ion export (GO:0071436)2.85613255
44cellular response to interleukin-15 (GO:0071350)2.82295314
45regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.81645453
46response to interleukin-15 (GO:0070672)2.80354295
47negative regulation of interleukin-12 production (GO:0032695)2.77185651
48regulation of myeloid leukocyte mediated immunity (GO:0002886)2.74800570
49regulation of dendritic cell antigen processing and presentation (GO:0002604)2.74324782
50antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.73825249
51L-amino acid import (GO:0043092)2.73419492
52glutamate receptor signaling pathway (GO:0007215)2.73211199
53regulation of isotype switching to IgG isotypes (GO:0048302)2.72649397
54regulation of tolerance induction (GO:0002643)2.72625871
55regulation of interferon-beta biosynthetic process (GO:0045357)2.71399184
56regulation of mast cell degranulation (GO:0043304)2.69935018
57regulation of T cell tolerance induction (GO:0002664)2.68567820
58response to peptidoglycan (GO:0032494)2.67240205
59regulation of leukocyte degranulation (GO:0043300)2.66966953
60regulation of regulatory T cell differentiation (GO:0045589)2.65275090
61negative regulation of glycoprotein biosynthetic process (GO:0010561)2.62892671
62synaptic vesicle exocytosis (GO:0016079)2.61281684
63regulation of regulated secretory pathway (GO:1903305)2.59876208
64T cell migration (GO:0072678)2.58594988
65neutrophil activation involved in immune response (GO:0002283)2.58098716
66positive regulation of CREB transcription factor activity (GO:0032793)2.56790107
67detection of biotic stimulus (GO:0009595)2.56324874
68T cell receptor signaling pathway (GO:0050852)2.55888751
69leukocyte migration involved in inflammatory response (GO:0002523)2.55778603
70negative regulation of phagocytosis (GO:0050765)2.54195590
71potassium ion import (GO:0010107)2.53782630
72mast cell degranulation (GO:0043303)2.53303233
73mast cell activation involved in immune response (GO:0002279)2.53303233
74Golgi to endosome transport (GO:0006895)2.52254509
75locomotory exploration behavior (GO:0035641)2.52134561
76macrophage activation (GO:0042116)2.52103429
77positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.51767200
78regulation of glutamate receptor signaling pathway (GO:1900449)2.51695376
79regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.51622917
80mast cell activation (GO:0045576)2.50785925
81histone H3-K4 trimethylation (GO:0080182)2.50349407
82nerve growth factor signaling pathway (GO:0038180)2.49844055
83negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.48336076
84negative regulation of cAMP-mediated signaling (GO:0043951)2.48061270
85negative regulation of interleukin-6 production (GO:0032715)2.46701027
86positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.46394062
87respiratory burst (GO:0045730)2.46221176
88negative regulation of innate immune response (GO:0045824)2.45384187
89regulation of mast cell activation involved in immune response (GO:0033006)2.45351526
90response to laminar fluid shear stress (GO:0034616)2.45211214
91response to type I interferon (GO:0034340)2.43313722
92negative regulation of type 2 immune response (GO:0002829)2.41987411
93regulation of T cell mediated cytotoxicity (GO:0001914)2.41802510
94negative regulation of T cell mediated immunity (GO:0002710)2.41537033
95G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.41110754
96positive regulation of granulocyte differentiation (GO:0030854)2.40800703
97vocalization behavior (GO:0071625)2.40652384
98antigen receptor-mediated signaling pathway (GO:0050851)2.40435887
99leukocyte aggregation (GO:0070486)2.40119132
100positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.39196240
101type I interferon signaling pathway (GO:0060337)2.39031175
102cellular response to type I interferon (GO:0071357)2.39031175
103tolerance induction (GO:0002507)2.38310567
104regulation of B cell differentiation (GO:0045577)2.38132778
105regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.37426300
106regulation of natural killer cell mediated immunity (GO:0002715)2.37426300
107neutrophil mediated immunity (GO:0002446)2.37425158
108synaptic vesicle endocytosis (GO:0048488)2.37203430
109long-term memory (GO:0007616)2.37115857
110positive regulation of histone deacetylation (GO:0031065)2.36305639
111modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.35975338
112positive regulation by organism of defense response of other organism involved in symbiotic interact2.35975338
113modulation by symbiont of host immune response (GO:0052553)2.35975338
114positive regulation by symbiont of host defense response (GO:0052509)2.35975338
115modulation by symbiont of host defense response (GO:0052031)2.35975338
116modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.35975338
117regulation of extracellular matrix disassembly (GO:0010715)2.35525271
118regulation of T-helper 2 cell differentiation (GO:0045628)2.35430167
119regulation of voltage-gated calcium channel activity (GO:1901385)2.34348555
120detection of molecule of bacterial origin (GO:0032490)2.34336278
121regulation of amyloid precursor protein catabolic process (GO:1902991)2.33878208
122modulation by symbiont of host cellular process (GO:0044068)2.33506962
123B cell receptor signaling pathway (GO:0050853)2.32340494
124T cell homeostasis (GO:0043029)2.31873073
125regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.31298611
126regulation of synaptic vesicle exocytosis (GO:2000300)2.30550240
127response to pheromone (GO:0019236)2.30485359
128regulation of synapse structural plasticity (GO:0051823)2.30014314
129germinal center formation (GO:0002467)2.30008521
130negative regulation of alpha-beta T cell activation (GO:0046636)2.28371323
131protein localization to synapse (GO:0035418)2.28045493
132myeloid cell activation involved in immune response (GO:0002275)2.27584113
133regulation of interleukin-12 biosynthetic process (GO:0045075)2.26699111
134neutrophil activation (GO:0042119)2.26414574
135microglial cell activation (GO:0001774)2.26344091
136myeloid leukocyte mediated immunity (GO:0002444)2.26080321
137regulation of excitatory postsynaptic membrane potential (GO:0060079)2.26070554
138gamma-aminobutyric acid signaling pathway (GO:0007214)2.25758037
139regulation of ARF GTPase activity (GO:0032312)2.25007637
140pigmentation (GO:0043473)2.24564944
141adult walking behavior (GO:0007628)2.24476500
142regulation of mast cell activation (GO:0033003)2.24271505
143positive regulation of Rap GTPase activity (GO:0032854)2.24169938
144response to muramyl dipeptide (GO:0032495)2.24089054
145negative regulation of lymphocyte mediated immunity (GO:0002707)2.23680873
146synaptic transmission, glutamatergic (GO:0035249)2.21914642
147membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.20388293
148protein kinase C signaling (GO:0070528)2.18984658
149membrane depolarization during action potential (GO:0086010)2.18679711
150T cell mediated immunity (GO:0002456)2.18118680
151amino acid import (GO:0043090)2.15230729
152potassium ion homeostasis (GO:0055075)2.14245249
153regulation of Rap GTPase activity (GO:0032317)2.13881258
154T cell costimulation (GO:0031295)2.13859159
155positive regulation of tolerance induction (GO:0002645)2.13220852
156activation of protein kinase A activity (GO:0034199)2.11610252
157lymphocyte costimulation (GO:0031294)2.11069247

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.65501313
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.35649021
3EZH2_22144423_ChIP-Seq_EOC_Human3.23439063
4VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.65649092
5DROSHA_22980978_ChIP-Seq_HELA_Human2.39844922
6RUNX_20019798_ChIP-Seq_JUKART_Human2.39377684
7LXR_22292898_ChIP-Seq_THP-1_Human2.37838235
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.15594917
9GBX2_23144817_ChIP-Seq_PC3_Human2.10681411
10MYC_22102868_ChIP-Seq_BL_Human2.09682620
11* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.04336758
12IKZF1_21737484_ChIP-ChIP_HCT116_Human2.03775443
13SMAD_19615063_ChIP-ChIP_OVARY_Human1.97168392
14ELK3_25401928_ChIP-Seq_HUVEC_Human1.96917791
15* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.92502473
16STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.88918255
17JARID2_20064375_ChIP-Seq_MESCs_Mouse1.87284495
18MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.83822900
19* SPI1_23127762_ChIP-Seq_K562_Human1.76829846
20SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.76398509
21EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.76166040
22SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.75546473
23KDM2B_26808549_Chip-Seq_SUP-B15_Human1.73034413
24Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.71378021
25RARB_27405468_Chip-Seq_BRAIN_Mouse1.69935061
26MAF_26560356_Chip-Seq_TH2_Human1.69565743
27* RUNX1_22412390_ChIP-Seq_EML_Mouse1.68240823
28SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.68158919
29MTF2_20144788_ChIP-Seq_MESCs_Mouse1.66288922
30IRF8_27001747_Chip-Seq_BMDM_Mouse1.66193764
31IRF8_21731497_ChIP-ChIP_J774_Mouse1.66113472
32RNF2_18974828_ChIP-Seq_MESCs_Mouse1.65645713
33EZH2_18974828_ChIP-Seq_MESCs_Mouse1.65645713
34BP1_19119308_ChIP-ChIP_Hs578T_Human1.63820195
35CDX2_19796622_ChIP-Seq_MESCs_Mouse1.63390180
36NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.61545199
37REST_21632747_ChIP-Seq_MESCs_Mouse1.53755939
38SUZ12_27294783_Chip-Seq_ESCs_Mouse1.50090375
39JARID2_20075857_ChIP-Seq_MESCs_Mouse1.45834279
40SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.45741389
41SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.45617960
42IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.45430983
43SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.43072319
44TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.43002383
45EZH2_27294783_Chip-Seq_ESCs_Mouse1.42215818
46NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.41339747
47P68_20966046_ChIP-Seq_HELA_Human1.39617692
48THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.38619517
49CTCF_27219007_Chip-Seq_ERYTHROID_Human1.38484188
50SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.38364698
51RNF2_27304074_Chip-Seq_ESCs_Mouse1.36858783
52CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.35532682
53* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.35325905
54KDM2B_26808549_Chip-Seq_DND41_Human1.34808761
55SA1_27219007_Chip-Seq_ERYTHROID_Human1.34194582
56VDR_24787735_ChIP-Seq_THP-1_Human1.30716524
57AR_21572438_ChIP-Seq_LNCaP_Human1.29792288
58GATA2_21666600_ChIP-Seq_HMVEC_Human1.29488497
59RACK7_27058665_Chip-Seq_MCF-7_Human1.29145201
60SMC4_20622854_ChIP-Seq_HELA_Human1.28550131
61RARG_19884340_ChIP-ChIP_MEFs_Mouse1.27825429
62E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.26141407
63SCL_19346495_ChIP-Seq_HPC-7_Human1.25331200
64* BCL6_27268052_Chip-Seq_Bcells_Human1.25006966
65* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.23816266
66BCOR_27268052_Chip-Seq_Bcells_Human1.23367354
67TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.22277022
68TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.20111155
69KDM2B_26808549_Chip-Seq_K562_Human1.19671952
70NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.19256177
71KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.19141248
72ZFP281_18757296_ChIP-ChIP_E14_Mouse1.19008817
73LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.18661677
74REST_18959480_ChIP-ChIP_MESCs_Mouse1.17404502
75PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.17091097
76STAT4_19710469_ChIP-ChIP_TH1__Mouse1.16955986
77KDM2B_26808549_Chip-Seq_JURKAT_Human1.16213541
78PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.15843307
79MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.14653709
80LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.13891201
81CTCF_27219007_Chip-Seq_Bcells_Human1.13413635
82VDR_24763502_ChIP-Seq_THP-1_Human1.13221119
83MAF_26560356_Chip-Seq_TH1_Human1.13021210
84SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.12927389
85ELF1_20517297_ChIP-Seq_JURKAT_Human1.12871587
86ZFP281_27345836_Chip-Seq_ESCs_Mouse1.12336669
87TCF7_22412390_ChIP-Seq_EML_Mouse1.11763389
88SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.10027606
89GATA1_19941826_ChIP-Seq_K562_Human1.09723218
90EZH2_27304074_Chip-Seq_ESCs_Mouse1.09670426
91ERG_21242973_ChIP-ChIP_JURKAT_Human1.09019934
92PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08860451
93TET1_21451524_ChIP-Seq_MESCs_Mouse1.08448425
94IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.08238640
95GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.07749330
96PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.07686673
97VDR_21846776_ChIP-Seq_THP-1_Human1.07215116
98* OCT4_19829295_ChIP-Seq_ESCs_Human1.06121962
99STAT6_21828071_ChIP-Seq_BEAS2B_Human1.05701851
100AHR_22903824_ChIP-Seq_MCF-7_Human1.05234089
101SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.04894474
102SPI1_23547873_ChIP-Seq_NB4_Human1.04111485
103ESR2_21235772_ChIP-Seq_MCF-7_Human1.03144477
104SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.02679712
105WT1_25993318_ChIP-Seq_PODOCYTE_Human1.02652834
106CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.02622978
107PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.02373621
108PU.1_20513432_ChIP-Seq_Bcells_Mouse1.02302904
109MYB_26560356_Chip-Seq_TH2_Human1.01734264
110CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.01406624
111ZNF217_24962896_ChIP-Seq_MCF-7_Human1.00904897
112UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.00823432
113MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.00782218
114ARNT_22903824_ChIP-Seq_MCF-7_Human1.00765495
115UTX_26944678_Chip-Seq_JUKART_Human1.00748979
116CTNNB1_20460455_ChIP-Seq_HCT116_Human1.00576445
117KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.00441397
118CREB1_26743006_Chip-Seq_LNCaP_Human1.00357009
119NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.99932524
120SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.99285808
121PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.99081502
122RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.98206495
123DNAJC2_21179169_ChIP-ChIP_NT2_Human0.98072649
124SMAD4_21799915_ChIP-Seq_A2780_Human0.97750925
125TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.96995165
126EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.95256633
127GATA1_19941827_ChIP-Seq_MEL_Mouse0.94184725
128SA1_27219007_Chip-Seq_Bcells_Human0.93620486
129GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93139431
130TP63_22573176_ChIP-Seq_HFKS_Human0.92842351
131EED_16625203_ChIP-ChIP_MESCs_Mouse0.92423902
132ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.92308008
133EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.91697854
134PU_27001747_Chip-Seq_BMDM_Mouse0.91164808
135AR_25329375_ChIP-Seq_VCAP_Human0.90076884
136* GATA3_27048872_Chip-Seq_THYMUS_Human0.89087434
137NR3C1_23031785_ChIP-Seq_PC12_Mouse0.88969754
138TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.88739612
139STAT3_23295773_ChIP-Seq_U87_Human0.84506976
140MYB_26560356_Chip-Seq_TH1_Human0.84153681
141MYB_21317192_ChIP-Seq_ERMYB_Mouse0.82768474
142MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.81679306
143RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.81027389
144AR_19668381_ChIP-Seq_PC3_Human0.81011332
145TCF4_23295773_ChIP-Seq_U87_Human0.79803767
146BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.79797115

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation5.32247468
2MP0000372_irregular_coat_pigmentation4.01811796
3MP0005171_absent_coat_pigmentation3.35861919
4MP0000015_abnormal_ear_pigmentation3.34820169
5MP0005174_abnormal_tail_pigmentation3.26052521
6MP0004859_abnormal_synaptic_plasticity3.18817761
7MP0004381_abnormal_hair_follicle2.97360396
8MP0004510_myositis2.48220062
9MP0003172_abnormal_lysosome_physiology2.29189919
10MP0000371_diluted_coat_color2.26156448
11MP0005058_abnormal_lysosome_morphology2.25724466
12MP0009046_muscle_twitch2.22068449
13MP0008260_abnormal_autophagy2.05960542
14MP0003880_abnormal_central_pattern2.00543052
15MP0003635_abnormal_synaptic_transmissio1.98193251
16MP0005409_darkened_coat_color1.96487537
17MP0003763_abnormal_thymus_physiology1.89258773
18MP0005075_abnormal_melanosome_morpholog1.86380905
19MP0002095_abnormal_skin_pigmentation1.83197751
20MP0003191_abnormal_cellular_cholesterol1.81941316
21MP0008569_lethality_at_weaning1.81495030
22MP0001533_abnormal_skeleton_physiology1.79312318
23MP0003136_yellow_coat_color1.74402892
24MP0002064_seizures1.73854116
25MP0001835_abnormal_antigen_presentation1.68299502
26MP0005671_abnormal_response_to1.65369016
27MP0002933_joint_inflammation1.64040583
28MP0003329_amyloid_beta_deposits1.64039175
29MP0009745_abnormal_behavioral_response1.63565512
30MP0005257_abnormal_intraocular_pressure1.62560931
31MP0005408_hypopigmentation1.62273975
32MP0009278_abnormal_bone_marrow1.59349458
33MP0000685_abnormal_immune_system1.54098561
34MP0010155_abnormal_intestine_physiology1.53467081
35MP0003828_pulmonary_edema1.52349631
36MP0005423_abnormal_somatic_nervous1.50062226
37MP0005387_immune_system_phenotype1.49698262
38MP0001790_abnormal_immune_system1.49698262
39MP0003279_aneurysm1.46923301
40MP0009333_abnormal_splenocyte_physiolog1.45962990
41MP0003183_abnormal_peptide_metabolism1.45136451
42MP0003303_peritoneal_inflammation1.40381466
43MP0002272_abnormal_nervous_system1.38072595
44MP0001800_abnormal_humoral_immune1.37079712
45MP0002166_altered_tumor_susceptibility1.36623870
46MP0005000_abnormal_immune_tolerance1.35899571
47MP0005310_abnormal_salivary_gland1.35588522
48MP0002067_abnormal_sensory_capabilities1.33329380
49MP0001968_abnormal_touch/_nociception1.31035519
50MP0002420_abnormal_adaptive_immunity1.30527314
51MP0002063_abnormal_learning/memory/cond1.30464896
52MP0002723_abnormal_immune_serum1.30344937
53MP0001819_abnormal_immune_cell1.30035273
54MP0000465_gastrointestinal_hemorrhage1.28043673
55MP0002419_abnormal_innate_immunity1.27278934
56MP0004130_abnormal_muscle_cell1.27174982
57MP0002075_abnormal_coat/hair_pigmentati1.27113434
58MP0001873_stomach_inflammation1.24541612
59MP0002452_abnormal_antigen_presenting1.23920736
60MP0001486_abnormal_startle_reflex1.23873176
61MP0002572_abnormal_emotion/affect_behav1.23146784
62MP0001986_abnormal_taste_sensitivity1.21877847
63MP0001845_abnormal_inflammatory_respons1.21320830
64MP0002138_abnormal_hepatobiliary_system1.19742135
65MP0000920_abnormal_myelination1.18838544
66MP0009840_abnormal_foam_cell1.18123321
67MP0001501_abnormal_sleep_pattern1.17944739
68MP0005451_abnormal_body_composition1.16353328
69MP0004742_abnormal_vestibular_system1.15347749
70MP0002735_abnormal_chemical_nociception1.13591755
71MP0006082_CNS_inflammation1.13380702
72MP0004858_abnormal_nervous_system1.12876941
73MP0001324_abnormal_eye_pigmentation1.10674412
74MP0002722_abnormal_immune_system1.09685349
75MP0003705_abnormal_hypodermis_morpholog1.07954567
76MP0002429_abnormal_blood_cell1.07949136
77MP0004883_abnormal_blood_vessel1.07564975
78MP0005025_abnormal_response_to1.07467402
79MP0005670_abnormal_white_adipose1.06650735
80MP0003633_abnormal_nervous_system1.06029189
81MP0000689_abnormal_spleen_morphology1.05660257
82MP0003866_abnormal_defecation1.05474455
83MP0002090_abnormal_vision1.05316914
84MP0004270_analgesia1.05140032
85MP0003436_decreased_susceptibility_to1.04007761
86MP0003075_altered_response_to1.03564081
87MP0003091_abnormal_cell_migration1.03485860
88MP0002638_abnormal_pupillary_reflex1.02444018
89MP0005464_abnormal_platelet_physiology1.02251353
90MP0004885_abnormal_endolymph1.02136049
91MP0002006_tumorigenesis1.01853763
92MP0005551_abnormal_eye_electrophysiolog1.00705885
93MP0001502_abnormal_circadian_rhythm0.99605022
94MP0001663_abnormal_digestive_system0.98558561
95MP0003300_gastrointestinal_ulcer0.98415531
96MP0008874_decreased_physiological_sensi0.97246984
97MP0002736_abnormal_nociception_after0.96372592
98MP0008961_abnormal_basal_metabolism0.94191187
99MP0005386_behavior/neurological_phenoty0.93411951
100MP0004924_abnormal_behavior0.93411951
101MP0008469_abnormal_protein_level0.92672563
102MP0002398_abnormal_bone_marrow0.92392586
103MP0003787_abnormal_imprinting0.92181494
104MP0003634_abnormal_glial_cell0.91797219
105MP0002184_abnormal_innervation0.91331598
106MP0001186_pigmentation_phenotype0.90997008
107MP0002653_abnormal_ependyma_morphology0.90344406
108MP0003724_increased_susceptibility_to0.90160013
109MP0003690_abnormal_glial_cell0.90067111
110MP0000716_abnormal_immune_system0.90018092
111MP0001970_abnormal_pain_threshold0.89488779
112MP0000703_abnormal_thymus_morphology0.88911182
113MP0005166_decreased_susceptibility_to0.88677707
114MP0002405_respiratory_system_inflammati0.88204224
115MP0000604_amyloidosis0.88100442
116MP0002734_abnormal_mechanical_nocicepti0.87607757
117MP0002998_abnormal_bone_remodeling0.87466802
118MP0001440_abnormal_grooming_behavior0.86794385
119MP0002557_abnormal_social/conspecific_i0.85774176
120MP0003045_fibrosis0.85464103
121MP0000249_abnormal_blood_vessel0.84596366
122MP0001849_ear_inflammation0.83640724
123MP0002148_abnormal_hypersensitivity_rea0.82723009
124MP0003879_abnormal_hair_cell0.81944393
125MP0002229_neurodegeneration0.81431540
126MP0005390_skeleton_phenotype0.80917000
127MP0004947_skin_inflammation0.80855849
128MP0002132_abnormal_respiratory_system0.80583767
129MP0001851_eye_inflammation0.80425438
130MP0000767_abnormal_smooth_muscle0.80190004
131MP0009785_altered_susceptibility_to0.79752496
132MP0000858_altered_metastatic_potential0.79626539
133MP0009764_decreased_sensitivity_to0.79216812
134MP0001348_abnormal_lacrimal_gland0.78826397
135MP0002909_abnormal_adrenal_gland0.74647162
136MP0001958_emphysema0.73759087
137MP0005167_abnormal_blood-brain_barrier0.73746303
138MP0000778_abnormal_nervous_system0.73580172
139MP0002822_catalepsy0.73113314
140MP0002396_abnormal_hematopoietic_system0.72572852

Predicted human phenotypes

RankGene SetZ-score
1Ocular albinism (HP:0001107)5.02724590
2Iris hypopigmentation (HP:0007730)4.49610871
3Aplasia/Hypoplasia of the macula (HP:0008059)4.06835151
4Stomatitis (HP:0010280)4.05853111
5Aplasia/Hypoplasia affecting the retina (HP:0008061)3.85282986
6Blue irides (HP:0000635)3.75271518
7Generalized hypopigmentation (HP:0007513)3.69871023
8Spontaneous hematomas (HP:0007420)3.69400551
9Supranuclear gaze palsy (HP:0000605)3.56167571
10Obstructive sleep apnea (HP:0002870)3.55129693
11Recurrent abscess formation (HP:0002722)3.34064000
12Focal motor seizures (HP:0011153)3.29611297
13Recurrent gram-negative bacterial infections (HP:0005420)3.25933963
14Febrile seizures (HP:0002373)3.20268119
15Increased cerebral lipofuscin (HP:0011813)3.19471302
16Gastrointestinal infarctions (HP:0005244)3.17170105
17Papilledema (HP:0001085)3.16185070
18Elevated erythrocyte sedimentation rate (HP:0003565)3.12171320
19Pustule (HP:0200039)3.10697151
20Progressive cerebellar ataxia (HP:0002073)3.07217242
21Hypoplasia of the fovea (HP:0007750)3.06066298
22Aplasia/Hypoplasia of the fovea (HP:0008060)3.06066298
23Increased IgE level (HP:0003212)3.01254040
24Diplopia (HP:0000651)2.98679036
25Abnormality of binocular vision (HP:0011514)2.98679036
26T lymphocytopenia (HP:0005403)2.91989803
27Cellulitis (HP:0100658)2.90107279
28Focal seizures (HP:0007359)2.86875529
29Gaze-evoked nystagmus (HP:0000640)2.84524628
30Recurrent cutaneous fungal infections (HP:0011370)2.80487327
31Chronic mucocutaneous candidiasis (HP:0002728)2.80487327
32Abnormality of T cell number (HP:0011839)2.78904640
33Visual hallucinations (HP:0002367)2.77743600
34Recurrent bacterial skin infections (HP:0005406)2.77519192
35Prolonged bleeding time (HP:0003010)2.73838205
36Increased neuronal autofluorescent lipopigment (HP:0002074)2.64620713
37Recurrent fungal infections (HP:0002841)2.63533366
38Hemiplegia (HP:0002301)2.63193444
39Abnormality of the fovea (HP:0000493)2.58957234
40Albinism (HP:0001022)2.57016367
41Action tremor (HP:0002345)2.56606230
42Encephalitis (HP:0002383)2.55899815
43Loss of speech (HP:0002371)2.50820284
44Vasculitis (HP:0002633)2.50628079
45Dysostosis multiplex (HP:0000943)2.50557376
46Atonic seizures (HP:0010819)2.49064899
47Cerebral aneurysm (HP:0004944)2.47630563
48Chest pain (HP:0100749)2.46680991
49Broad face (HP:0000283)2.45065829
50Gastrointestinal inflammation (HP:0004386)2.42384851
51Epileptic encephalopathy (HP:0200134)2.39875744
52Colitis (HP:0002583)2.39353927
53Myokymia (HP:0002411)2.38865460
54Abnormality of glycolipid metabolism (HP:0010969)2.38283579
55Abnormality of liposaccharide metabolism (HP:0010968)2.38283579
56Abnormality of glycosphingolipid metabolism (HP:0004343)2.38283579
57Eczematoid dermatitis (HP:0000976)2.37468599
58Mediastinal lymphadenopathy (HP:0100721)2.36037557
59Slow saccadic eye movements (HP:0000514)2.34892905
60Genetic anticipation (HP:0003743)2.34725173
61Abnormality of the fingertips (HP:0001211)2.34308873
62Pulmonary infiltrates (HP:0002113)2.33450186
63Ankle clonus (HP:0011448)2.31673045
64Episodic fever (HP:0001954)2.31287347
65Myositis (HP:0100614)2.31074182
66Hypochromic anemia (HP:0001931)2.30021806
67Keratoconjunctivitis sicca (HP:0001097)2.25684776
68Abnormal delayed hypersensitivity skin test (HP:0002963)2.25214333
69Amyloidosis (HP:0011034)2.24291421
70Neuronal loss in central nervous system (HP:0002529)2.22402407
71Abnormality of macrophages (HP:0004311)2.21841442
72Peritonitis (HP:0002586)2.19744341
73Congenital stationary night blindness (HP:0007642)2.19737902
74Recurrent skin infections (HP:0001581)2.19188092
75Dysmetria (HP:0001310)2.18486139
76Epistaxis (HP:0000421)2.18441313
77Gingivitis (HP:0000230)2.15214339
78Retrobulbar optic neuritis (HP:0100654)2.14066243
79Optic neuritis (HP:0100653)2.14066243
80Truncal ataxia (HP:0002078)2.12305856
81Thin bony cortex (HP:0002753)2.09192045
82Keratoconjunctivitis (HP:0001096)2.08478903
83Pulmonary embolism (HP:0002204)2.07942748
84Thyroiditis (HP:0100646)2.07419703
85Abnormality of polysaccharide metabolism (HP:0011012)2.07384848
86Abnormality of glycosaminoglycan metabolism (HP:0004371)2.07384848
87Abnormality of mucopolysaccharide metabolism (HP:0011020)2.07384848
88Dysmetric saccades (HP:0000641)2.06904044
89Autoimmune thrombocytopenia (HP:0001973)2.06399683
90Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.06126529
91Frequent falls (HP:0002359)2.06049114
92Abnormality of the nasal mucosa (HP:0000433)2.04516441
93Progressive inability to walk (HP:0002505)2.04099476
94Absence seizures (HP:0002121)2.03848217
95Panhypogammaglobulinemia (HP:0003139)2.03617546
96Segmental peripheral demyelination/remyelination (HP:0003481)2.01852653
97Hemorrhage of the eye (HP:0011885)2.01619149
98Neurofibrillary tangles (HP:0002185)2.00874898
99Hematochezia (HP:0002573)1.99876448
100Severe combined immunodeficiency (HP:0004430)1.99808463
101Vacuolated lymphocytes (HP:0001922)1.99506059
102Abnormality of vision evoked potentials (HP:0000649)1.99138214
103Congenital sensorineural hearing impairment (HP:0008527)1.98904899
104Hypochromic microcytic anemia (HP:0004840)1.98848426
105Generalized hypopigmentation of hair (HP:0011358)1.98063066
106Broad-based gait (HP:0002136)1.97496944
107Scanning speech (HP:0002168)1.97411714
108Papilloma (HP:0012740)1.97204819
109Verrucae (HP:0200043)1.97204819
110Spinal canal stenosis (HP:0003416)1.95612295
111Hemiparesis (HP:0001269)1.94913346
112Agammaglobulinemia (HP:0004432)1.94696406
113Chronic obstructive pulmonary disease (HP:0006510)1.92284151
114Obstructive lung disease (HP:0006536)1.92284151
115Impaired smooth pursuit (HP:0007772)1.90810360
116Dialeptic seizures (HP:0011146)1.90327643
117Acne (HP:0001061)1.89788638
118Leukocytosis (HP:0001974)1.89656531
119Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.89061608
120J-shaped sella turcica (HP:0002680)1.88675835
121Mask-like facies (HP:0000298)1.88079266
122Abnormality of saccadic eye movements (HP:0000570)1.87853157
123Chronic otitis media (HP:0000389)1.87384455
124Depression (HP:0000716)1.87252160
125Onion bulb formation (HP:0003383)1.86575677
126Urinary bladder sphincter dysfunction (HP:0002839)1.85868172
127Recurrent viral infections (HP:0004429)1.84481281
128Gingival bleeding (HP:0000225)1.83289665
129Mucopolysacchariduria (HP:0008155)1.81516607
130Urinary glycosaminoglycan excretion (HP:0003541)1.81516607
131Hypoplasia of the iris (HP:0007676)1.81384370
132Lymphopenia (HP:0001888)1.81249860
133Mutism (HP:0002300)1.81116235
134Interstitial pulmonary disease (HP:0006530)1.81097876
135Abnormality of the endocardium (HP:0004306)1.80800472
136Hemoptysis (HP:0002105)1.80109484
137Microcytic anemia (HP:0001935)1.79325050
138Cerebral inclusion bodies (HP:0100314)1.78382959
139Inflammation of the large intestine (HP:0002037)1.78279880
140Annular pancreas (HP:0001734)1.78261100
141Psychosis (HP:0000709)1.77646658
142Restrictive lung disease (HP:0002091)1.76896649
143Osteomyelitis (HP:0002754)1.76773583
144Rapidly progressive (HP:0003678)1.75776581
145Urticaria (HP:0001025)1.75213736
146Easy fatigability (HP:0003388)1.75047561
147Polygenic inheritance (HP:0010982)1.72760255
148Dysdiadochokinesis (HP:0002075)1.72609572
149Orchitis (HP:0100796)1.72598181
150Meningitis (HP:0001287)1.70883461

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K12.92611785
2TXK2.86053127
3MAP3K132.82894611
4SIK22.77508005
5ERN12.73369762
6RIPK42.68538887
7FES2.46855494
8CAMKK22.45588930
9MST1R2.08857728
10CAMK1G1.97768451
11TNIK1.85726772
12SIK11.82358475
13MAP2K31.77906249
14PRPF4B1.77578787
15IKBKE1.77309262
16DAPK21.74219105
17JAK11.68600508
18MARK31.66905525
19CAMKK11.61140021
20ITK1.59083780
21KIT1.52887923
22PRKCH1.51985836
23MAP3K111.49329357
24ZAP701.48021731
25TYK21.47558407
26MAP3K141.45323825
27CAMK1D1.44583515
28TAOK11.43054332
29JAK31.40900836
30HCK1.37683654
31NTRK31.36338532
32CDC42BPA1.29019073
33PAK61.26621471
34TBK11.24648519
35IRAK31.18551516
36LCK1.18188747
37MARK21.18019440
38STK381.16770973
39NTRK21.15781154
40TNK21.14508188
41SYK1.13190198
42SMG11.13122386
43MAP3K31.05068374
44PRKD31.04949233
45MAP3K91.03096363
46SGK21.00885592
47RIPK10.99589779
48CAMK10.98459569
49TAOK30.97815898
50MAP3K100.97455268
51SGK30.97449055
52SIK30.97146105
53IRAK40.96209885
54PRKD20.95968276
55MAPK120.92785283
56NLK0.89289495
57PDK10.87720479
58SGK2230.87219552
59SGK4940.87219552
60CASK0.86396125
61WNK10.85750545
62EPHA40.85061881
63ICK0.84348622
64MAP2K70.83782393
65CDK50.83457373
66MAP3K70.83419906
67TIE10.83379189
68TTN0.82321684
69PKN10.80028812
70PRKCQ0.79628390
71HIPK20.78696923
72FGFR30.78626154
73FGFR40.78280071
74CSK0.78162683
75JAK20.76776863
76TGFBR20.76673812
77TEC0.76135652
78IKBKB0.76085665
79KSR20.75634033
80GRK60.75472006
81MAP3K40.75102168
82FYN0.74853483
83STK110.73182000
84PTK2B0.72384076
85CLK10.71972533
86CAMK40.71456542
87UHMK10.68543209
88TYRO30.68092382
89MAPK70.67741411
90DYRK1B0.67731969
91MAPK150.66631598
92BLK0.66563836
93FGR0.66132446
94PDPK10.65885864
95RPS6KA20.65132626
96BMX0.64824240
97PDGFRB0.63372737
98EPHA30.63363106
99SGK10.63182654
100PHKG20.62482455
101PHKG10.62482455
102CSF1R0.62431505
103CDK190.62099263
104PTK60.61263755
105PKN20.61096196
106DAPK10.59163255
107MARK10.57216213
108EPHB10.56785216
109MAP2K60.56641270
110MAP3K10.54725325
111TRIB30.53585528
112MAP3K60.50151744
113RPS6KL10.49769961
114RPS6KC10.49769961
115RET0.49755392
116IRAK10.49223501
117LYN0.48289484
118KDR0.47744987
119MUSK0.47711806
120PRKD10.47305768
121BTK0.47305630
122DAPK30.46114681
123MINK10.45310712
124MAPK110.44967439
125SRC0.44804105
126RPS6KA60.44507372
127DYRK1A0.42639539
128MAP3K120.42126462
129IRAK20.41486777

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047211.97954677
2Nicotine addiction_Homo sapiens_hsa050331.94744127
3Morphine addiction_Homo sapiens_hsa050321.75336977
4T cell receptor signaling pathway_Homo sapiens_hsa046601.70401935
5Primary immunodeficiency_Homo sapiens_hsa053401.68893411
6Phosphatidylinositol signaling system_Homo sapiens_hsa040701.67119343
7Olfactory transduction_Homo sapiens_hsa047401.65784105
8Osteoclast differentiation_Homo sapiens_hsa043801.60904964
9Glutamatergic synapse_Homo sapiens_hsa047241.60753218
10Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.60016897
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.58544367
12Circadian entrainment_Homo sapiens_hsa047131.54553458
13Collecting duct acid secretion_Homo sapiens_hsa049661.54031446
14Salivary secretion_Homo sapiens_hsa049701.52405903
15Aldosterone synthesis and secretion_Homo sapiens_hsa049251.46474187
16Long-term potentiation_Homo sapiens_hsa047201.41582820
17GABAergic synapse_Homo sapiens_hsa047271.41153143
18Staphylococcus aureus infection_Homo sapiens_hsa051501.40430202
19Notch signaling pathway_Homo sapiens_hsa043301.37245232
20Cholinergic synapse_Homo sapiens_hsa047251.35029656
21B cell receptor signaling pathway_Homo sapiens_hsa046621.33532217
22Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.33124643
23Type II diabetes mellitus_Homo sapiens_hsa049301.28751734
24Gastric acid secretion_Homo sapiens_hsa049711.26969314
25Non-small cell lung cancer_Homo sapiens_hsa052231.26639446
26Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.24055925
27Autoimmune thyroid disease_Homo sapiens_hsa053201.22570350
28Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.18085162
29Renin secretion_Homo sapiens_hsa049241.17583095
30Chemokine signaling pathway_Homo sapiens_hsa040621.16841618
31Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.14883766
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.14070325
33Long-term depression_Homo sapiens_hsa047301.13862663
34Insulin secretion_Homo sapiens_hsa049111.12988320
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.12310810
36Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.11409370
37Inositol phosphate metabolism_Homo sapiens_hsa005621.10869286
38Lysosome_Homo sapiens_hsa041421.09979600
39Oxytocin signaling pathway_Homo sapiens_hsa049211.09410449
40Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.08596518
41Measles_Homo sapiens_hsa051621.07506819
42Phospholipase D signaling pathway_Homo sapiens_hsa040721.06856377
43Glycosaminoglycan degradation_Homo sapiens_hsa005311.06731810
44Taste transduction_Homo sapiens_hsa047421.05667847
45Calcium signaling pathway_Homo sapiens_hsa040201.04397230
46NF-kappa B signaling pathway_Homo sapiens_hsa040641.04299415
47Rheumatoid arthritis_Homo sapiens_hsa053231.01204813
48Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.99892634
49Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.99720126
50Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.98796564
51Dopaminergic synapse_Homo sapiens_hsa047280.97571990
52Toll-like receptor signaling pathway_Homo sapiens_hsa046200.96863731
53Carbohydrate digestion and absorption_Homo sapiens_hsa049730.96392385
54GnRH signaling pathway_Homo sapiens_hsa049120.94704051
55Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.94413705
56cAMP signaling pathway_Homo sapiens_hsa040240.93172858
57Leishmaniasis_Homo sapiens_hsa051400.92065524
58Neurotrophin signaling pathway_Homo sapiens_hsa047220.91832804
59Pancreatic cancer_Homo sapiens_hsa052120.91178088
60Amphetamine addiction_Homo sapiens_hsa050310.90398256
61Type I diabetes mellitus_Homo sapiens_hsa049400.90343019
62Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.89826416
63Tuberculosis_Homo sapiens_hsa051520.87318733
64Endometrial cancer_Homo sapiens_hsa052130.85773503
65Other glycan degradation_Homo sapiens_hsa005110.84576606
66cGMP-PKG signaling pathway_Homo sapiens_hsa040220.83978472
67Influenza A_Homo sapiens_hsa051640.82632111
68Acute myeloid leukemia_Homo sapiens_hsa052210.82288499
69Platelet activation_Homo sapiens_hsa046110.81917708
70Melanogenesis_Homo sapiens_hsa049160.81849150
71Choline metabolism in cancer_Homo sapiens_hsa052310.81132985
72VEGF signaling pathway_Homo sapiens_hsa043700.80665894
73Phagosome_Homo sapiens_hsa041450.79557361
74Sphingolipid signaling pathway_Homo sapiens_hsa040710.79360507
75Hepatitis B_Homo sapiens_hsa051610.78795595
76Vascular smooth muscle contraction_Homo sapiens_hsa042700.78773817
77Hepatitis C_Homo sapiens_hsa051600.77614033
78Jak-STAT signaling pathway_Homo sapiens_hsa046300.77540337
79Serotonergic synapse_Homo sapiens_hsa047260.77265894
80Intestinal immune network for IgA production_Homo sapiens_hsa046720.77202523
81Pancreatic secretion_Homo sapiens_hsa049720.76973239
82Endocytosis_Homo sapiens_hsa041440.76966313
83Viral myocarditis_Homo sapiens_hsa054160.76375452
84Allograft rejection_Homo sapiens_hsa053300.75486352
85Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.74224626
86Colorectal cancer_Homo sapiens_hsa052100.73990084
87Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.73626357
88MAPK signaling pathway_Homo sapiens_hsa040100.73068011
89Pertussis_Homo sapiens_hsa051330.72926617
90NOD-like receptor signaling pathway_Homo sapiens_hsa046210.72841299
91Vibrio cholerae infection_Homo sapiens_hsa051100.72183341
92Antigen processing and presentation_Homo sapiens_hsa046120.71953619
93RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.71946535
94Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.71189677
95Glioma_Homo sapiens_hsa052140.70972881
96ErbB signaling pathway_Homo sapiens_hsa040120.70941608
97Dilated cardiomyopathy_Homo sapiens_hsa054140.70911876
98Hematopoietic cell lineage_Homo sapiens_hsa046400.70853063
99Estrogen signaling pathway_Homo sapiens_hsa049150.70795571
100TNF signaling pathway_Homo sapiens_hsa046680.70343925
101Renal cell carcinoma_Homo sapiens_hsa052110.70339953
102Glycerophospholipid metabolism_Homo sapiens_hsa005640.69912739
103Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.68702364
104Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.67004805
105Malaria_Homo sapiens_hsa051440.66769519
106Axon guidance_Homo sapiens_hsa043600.65963226
107Rap1 signaling pathway_Homo sapiens_hsa040150.65919973
108Toxoplasmosis_Homo sapiens_hsa051450.65723223
109Leukocyte transendothelial migration_Homo sapiens_hsa046700.64817750
110Phototransduction_Homo sapiens_hsa047440.64551269
111Graft-versus-host disease_Homo sapiens_hsa053320.64072316
112Adipocytokine signaling pathway_Homo sapiens_hsa049200.63070020
113Chronic myeloid leukemia_Homo sapiens_hsa052200.62918247
114Prolactin signaling pathway_Homo sapiens_hsa049170.62459866
115Salmonella infection_Homo sapiens_hsa051320.62386256
116Dorso-ventral axis formation_Homo sapiens_hsa043200.62313294
117Cocaine addiction_Homo sapiens_hsa050300.61627530
118AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.61572948
119Ras signaling pathway_Homo sapiens_hsa040140.61208765
120Insulin resistance_Homo sapiens_hsa049310.60740669
121FoxO signaling pathway_Homo sapiens_hsa040680.60669629
122mTOR signaling pathway_Homo sapiens_hsa041500.60090587
123Longevity regulating pathway - mammal_Homo sapiens_hsa042110.59338405
124African trypanosomiasis_Homo sapiens_hsa051430.59319957

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