Rank | Gene Set | Z-score |
---|---|---|
1 | cerebellar granule cell differentiation (GO:0021707) | 4.56188053 |
2 | locomotory exploration behavior (GO:0035641) | 4.49974290 |
3 | synaptic vesicle maturation (GO:0016188) | 4.36008898 |
4 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.34860689 |
5 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.21982268 |
6 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.01604439 |
7 | vocalization behavior (GO:0071625) | 3.79274491 |
8 | amino acid import (GO:0043090) | 3.76246025 |
9 | glutamate secretion (GO:0014047) | 3.75929421 |
10 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.74703492 |
11 | regulation of synapse maturation (GO:0090128) | 3.74038269 |
12 | regulation of synapse structural plasticity (GO:0051823) | 3.62640673 |
13 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.61409567 |
14 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.59895423 |
15 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.58362269 |
16 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.56601169 |
17 | synaptic vesicle exocytosis (GO:0016079) | 3.55177629 |
18 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.54838179 |
19 | sodium ion export (GO:0071436) | 3.52754354 |
20 | cellular potassium ion homeostasis (GO:0030007) | 3.48699020 |
21 | neurotransmitter secretion (GO:0007269) | 3.39200353 |
22 | neuronal action potential propagation (GO:0019227) | 3.35721703 |
23 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.33002512 |
24 | gamma-aminobutyric acid transport (GO:0015812) | 3.32511356 |
25 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.31899040 |
26 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.29663684 |
27 | axon ensheathment in central nervous system (GO:0032291) | 3.29496864 |
28 | central nervous system myelination (GO:0022010) | 3.29496864 |
29 | positive regulation of dendritic spine development (GO:0060999) | 3.26373528 |
30 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.23862659 |
31 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.15342071 |
32 | activation of protein kinase A activity (GO:0034199) | 3.12643071 |
33 | layer formation in cerebral cortex (GO:0021819) | 3.11967976 |
34 | synaptic vesicle endocytosis (GO:0048488) | 3.06151509 |
35 | regulation of synaptic vesicle transport (GO:1902803) | 3.05262058 |
36 | exploration behavior (GO:0035640) | 3.05025365 |
37 | postsynaptic membrane organization (GO:0001941) | 3.04415153 |
38 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.02392598 |
39 | cell communication by electrical coupling (GO:0010644) | 3.02028504 |
40 | prepulse inhibition (GO:0060134) | 2.98045496 |
41 | dicarboxylic acid biosynthetic process (GO:0043650) | 2.93846509 |
42 | long-term memory (GO:0007616) | 2.93692870 |
43 | regulation of vesicle fusion (GO:0031338) | 2.91429366 |
44 | glutamate receptor signaling pathway (GO:0007215) | 2.91124026 |
45 | protein localization to synapse (GO:0035418) | 2.90881214 |
46 | neuromuscular process controlling balance (GO:0050885) | 2.90853100 |
47 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.88881489 |
48 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.87612401 |
49 | potassium ion import (GO:0010107) | 2.87534879 |
50 | negative regulation of dendrite morphogenesis (GO:0050774) | 2.86542292 |
51 | dendritic spine morphogenesis (GO:0060997) | 2.86383041 |
52 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 2.85908162 |
53 | cellular sodium ion homeostasis (GO:0006883) | 2.85169492 |
54 | synaptic transmission, glutamatergic (GO:0035249) | 2.85139335 |
55 | glycine transport (GO:0015816) | 2.81335975 |
56 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.80444894 |
57 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.80411906 |
58 | regulation of cell communication by electrical coupling (GO:0010649) | 2.74939865 |
59 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.74264772 |
60 | neuron-neuron synaptic transmission (GO:0007270) | 2.73436998 |
61 | chemosensory behavior (GO:0007635) | 2.72657947 |
62 | proline transport (GO:0015824) | 2.71836091 |
63 | detection of calcium ion (GO:0005513) | 2.70103112 |
64 | regulation of neurotransmitter transport (GO:0051588) | 2.69129377 |
65 | neurotransmitter transport (GO:0006836) | 2.67575405 |
66 | membrane depolarization during action potential (GO:0086010) | 2.67129343 |
67 | acidic amino acid transport (GO:0015800) | 2.65809407 |
68 | positive regulation of membrane potential (GO:0045838) | 2.65312948 |
69 | creatine metabolic process (GO:0006600) | 2.65066003 |
70 | alanine transport (GO:0032328) | 2.64587219 |
71 | regulation of postsynaptic membrane potential (GO:0060078) | 2.61654302 |
72 | glutamate metabolic process (GO:0006536) | 2.61589084 |
73 | striatum development (GO:0021756) | 2.61028741 |
74 | positive regulation of dendrite development (GO:1900006) | 2.60717975 |
75 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 2.60455451 |
76 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.60225325 |
77 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.59878355 |
78 | regulation of neurotransmitter levels (GO:0001505) | 2.58894360 |
79 | cell communication involved in cardiac conduction (GO:0086065) | 2.58869272 |
80 | regulation of synaptic plasticity (GO:0048167) | 2.58634591 |
81 | regulation of ARF protein signal transduction (GO:0032012) | 2.56960499 |
82 | neuromuscular process controlling posture (GO:0050884) | 2.56564722 |
83 | dendritic spine organization (GO:0097061) | 2.55880175 |
84 | behavioral response to cocaine (GO:0048148) | 2.53893374 |
85 | neurotransmitter uptake (GO:0001504) | 2.53271381 |
86 | neuromuscular synaptic transmission (GO:0007274) | 2.53044458 |
87 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.52590428 |
88 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.52553747 |
89 | cerebellar Purkinje cell layer development (GO:0021680) | 2.51083610 |
90 | positive regulation of synapse maturation (GO:0090129) | 2.50701814 |
91 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 2.50580149 |
92 | L-phenylalanine catabolic process (GO:0006559) | 2.50580149 |
93 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 2.50344832 |
94 | regulation of sodium ion transmembrane transporter activity (GO:2000649) | 2.49589738 |
95 | regulation of sodium ion transmembrane transport (GO:1902305) | 2.49541413 |
96 | alpha-linolenic acid metabolic process (GO:0036109) | 2.48559068 |
97 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.48455089 |
98 | sodium ion homeostasis (GO:0055078) | 2.48249985 |
99 | regulation of female receptivity (GO:0045924) | 2.48137284 |
100 | auditory behavior (GO:0031223) | 2.46637932 |
101 | regulation of synaptic transmission (GO:0050804) | 2.46302186 |
102 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.46222522 |
103 | cardiac muscle contraction (GO:0060048) | 2.45018790 |
104 | lysine metabolic process (GO:0006553) | 2.44336605 |
105 | lysine catabolic process (GO:0006554) | 2.44336605 |
106 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 2.43331017 |
107 | NADH metabolic process (GO:0006734) | 2.42892850 |
108 | dicarboxylic acid catabolic process (GO:0043649) | 2.42077942 |
109 | potassium ion homeostasis (GO:0055075) | 2.42009850 |
110 | dendrite morphogenesis (GO:0048813) | 2.41753024 |
111 | dicarboxylic acid transport (GO:0006835) | 2.41298633 |
112 | mating behavior (GO:0007617) | 2.40844228 |
113 | neuronal ion channel clustering (GO:0045161) | 2.40278072 |
114 | transmission of nerve impulse (GO:0019226) | 2.40164263 |
115 | membrane depolarization (GO:0051899) | 2.38514934 |
116 | long-term synaptic potentiation (GO:0060291) | 2.38183341 |
117 | L-amino acid import (GO:0043092) | 2.38086645 |
118 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.37826276 |
119 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.36363906 |
120 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 2.36220245 |
121 | regulation of dendritic spine development (GO:0060998) | 2.34167479 |
122 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.32565939 |
123 | L-phenylalanine metabolic process (GO:0006558) | 2.32565939 |
124 | membrane hyperpolarization (GO:0060081) | 2.32328655 |
125 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.32313396 |
126 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.31611215 |
127 | regulation of membrane repolarization (GO:0060306) | 2.30911240 |
128 | response to auditory stimulus (GO:0010996) | 2.30252490 |
129 | aspartate family amino acid catabolic process (GO:0009068) | 2.29499899 |
130 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.28471953 |
131 | positive regulation of neurotransmitter transport (GO:0051590) | 2.27333826 |
132 | long term synaptic depression (GO:0060292) | 2.27176335 |
133 | regulation of neurotransmitter secretion (GO:0046928) | 2.26454385 |
134 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.26321034 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.89453289 |
2 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.56493562 |
3 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.49746480 |
4 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.49022548 |
5 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.46441580 |
6 | * RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.44658118 |
7 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.30615822 |
8 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.30615822 |
9 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.23745487 |
10 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.21812468 |
11 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.20239621 |
12 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.18182533 |
13 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.12930018 |
14 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.09154534 |
15 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.06566442 |
16 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.04262716 |
17 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.97642330 |
18 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.95098652 |
19 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.89342415 |
20 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.88792559 |
21 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.87071181 |
22 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.85210040 |
23 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.76681175 |
24 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.72995765 |
25 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.72717035 |
26 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.71110903 |
27 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.69878150 |
28 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.69295730 |
29 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.68650456 |
30 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.68403096 |
31 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.60160687 |
32 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.58158662 |
33 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.54920226 |
34 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.52270983 |
35 | * SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.51640102 |
36 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.49144737 |
37 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.46586232 |
38 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.46410658 |
39 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.43131957 |
40 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.42117141 |
41 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.40301714 |
42 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.38276757 |
43 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.37615426 |
44 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.36927949 |
45 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.30888221 |
46 | KDM2B_26808549_Chip-Seq_K562_Human | 1.29258236 |
47 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.26679317 |
48 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.24769211 |
49 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.23267103 |
50 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.23139291 |
51 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.22514285 |
52 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.21849140 |
53 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.19483642 |
54 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.19394999 |
55 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.19376743 |
56 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.19250063 |
57 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.18279404 |
58 | * SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.16573375 |
59 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.16356216 |
60 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.15409652 |
61 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.15136209 |
62 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.14918859 |
63 | * KDM2B_26808549_Chip-Seq_DND41_Human | 1.14682287 |
64 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.14622614 |
65 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.14254372 |
66 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.13588083 |
67 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.13535538 |
68 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.12402240 |
69 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.11565777 |
70 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.10928228 |
71 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.10774564 |
72 | AR_19668381_ChIP-Seq_PC3_Human | 1.10611166 |
73 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.09754426 |
74 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.09151285 |
75 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.08045848 |
76 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.07728415 |
77 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.07231026 |
78 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.06902117 |
79 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.06902117 |
80 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.05536714 |
81 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.03536404 |
82 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.02045708 |
83 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.01993413 |
84 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.01822796 |
85 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.01454674 |
86 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.00417428 |
87 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.00261516 |
88 | P68_20966046_ChIP-Seq_HELA_Human | 0.99954327 |
89 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.99422088 |
90 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.98773613 |
91 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.98763710 |
92 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.98533498 |
93 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.98096385 |
94 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.97154462 |
95 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.96030156 |
96 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.95771755 |
97 | RXR_22108803_ChIP-Seq_LS180_Human | 0.94644586 |
98 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.94415886 |
99 | STAT3_23295773_ChIP-Seq_U87_Human | 0.93883782 |
100 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.93484111 |
101 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.92821012 |
102 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.92754307 |
103 | * CLOCK_20551151_ChIP-Seq_293T_Human | 0.92434975 |
104 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.91064850 |
105 | AR_25329375_ChIP-Seq_VCAP_Human | 0.90739456 |
106 | * TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.90518410 |
107 | * TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.90346674 |
108 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.87945071 |
109 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.87572974 |
110 | TP53_16413492_ChIP-PET_HCT116_Human | 0.87414003 |
111 | * LXR_22292898_ChIP-Seq_THP-1_Human | 0.86509077 |
112 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 0.86378373 |
113 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.85945235 |
114 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.85890791 |
115 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.85841458 |
116 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.85657734 |
117 | * KLF4_19829295_ChIP-Seq_ESCs_Human | 0.85565957 |
118 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.85046934 |
119 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.84400538 |
120 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.84286208 |
121 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.84082997 |
122 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.83697137 |
123 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.83526562 |
124 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.83182521 |
125 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.82909053 |
126 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.82434893 |
127 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.81683258 |
128 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.81454766 |
129 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.80882261 |
130 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.80877448 |
131 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.80525026 |
132 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.80203190 |
133 | * TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.79559809 |
134 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.78516851 |
135 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.78036935 |
136 | * DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.77759766 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.50525221 |
2 | MP0002822_catalepsy | 4.03996755 |
3 | MP0003635_abnormal_synaptic_transmissio | 3.27725765 |
4 | MP0003880_abnormal_central_pattern | 2.88732517 |
5 | MP0004270_analgesia | 2.82478764 |
6 | MP0009745_abnormal_behavioral_response | 2.76382221 |
7 | MP0002139_abnormal_hepatobiliary_system | 2.63305780 |
8 | MP0005360_urolithiasis | 2.58989273 |
9 | MP0002063_abnormal_learning/memory/cond | 2.56200993 |
10 | * MP0002064_seizures | 2.41186740 |
11 | MP0009046_muscle_twitch | 2.37254688 |
12 | MP0005085_abnormal_gallbladder_physiolo | 2.22983530 |
13 | MP0009780_abnormal_chondrocyte_physiolo | 2.05485851 |
14 | MP0002572_abnormal_emotion/affect_behav | 2.04273850 |
15 | MP0001486_abnormal_startle_reflex | 2.02948556 |
16 | MP0002272_abnormal_nervous_system | 2.00781008 |
17 | MP0003329_amyloid_beta_deposits | 1.99456852 |
18 | MP0002837_dystrophic_cardiac_calcinosis | 1.98882663 |
19 | MP0000751_myopathy | 1.97331220 |
20 | MP0005365_abnormal_bile_salt | 1.93576881 |
21 | MP0002909_abnormal_adrenal_gland | 1.90267503 |
22 | MP0001501_abnormal_sleep_pattern | 1.90089983 |
23 | MP0008875_abnormal_xenobiotic_pharmacok | 1.88686366 |
24 | MP0004130_abnormal_muscle_cell | 1.86578573 |
25 | MP0001968_abnormal_touch/_nociception | 1.80084114 |
26 | MP0005423_abnormal_somatic_nervous | 1.73504785 |
27 | MP0002734_abnormal_mechanical_nocicepti | 1.72108775 |
28 | MP0008569_lethality_at_weaning | 1.68641911 |
29 | MP0010329_abnormal_lipoprotein_level | 1.64469536 |
30 | MP0001440_abnormal_grooming_behavior | 1.57016855 |
31 | MP0003690_abnormal_glial_cell | 1.51698317 |
32 | MP0004885_abnormal_endolymph | 1.48528457 |
33 | MP0004145_abnormal_muscle_electrophysio | 1.46099570 |
34 | MP0004858_abnormal_nervous_system | 1.41833862 |
35 | MP0003633_abnormal_nervous_system | 1.41007689 |
36 | MP0005646_abnormal_pituitary_gland | 1.39021680 |
37 | MP0003252_abnormal_bile_duct | 1.38836406 |
38 | MP0008961_abnormal_basal_metabolism | 1.38536592 |
39 | MP0005409_darkened_coat_color | 1.35939527 |
40 | MP0003075_altered_response_to | 1.35578134 |
41 | MP0002067_abnormal_sensory_capabilities | 1.34344196 |
42 | MP0005167_abnormal_blood-brain_barrier | 1.31739473 |
43 | MP0004043_abnormal_pH_regulation | 1.31438018 |
44 | MP0004924_abnormal_behavior | 1.31201616 |
45 | MP0005386_behavior/neurological_phenoty | 1.31201616 |
46 | MP0003646_muscle_fatigue | 1.30241159 |
47 | MP0000013_abnormal_adipose_tissue | 1.28326832 |
48 | MP0003879_abnormal_hair_cell | 1.27802429 |
49 | MP0005535_abnormal_body_temperature | 1.27676715 |
50 | MP0004215_abnormal_myocardial_fiber | 1.25122374 |
51 | MP0002090_abnormal_vision | 1.23526762 |
52 | MP0004036_abnormal_muscle_relaxation | 1.22401338 |
53 | MP0003634_abnormal_glial_cell | 1.21520531 |
54 | MP0001984_abnormal_olfaction | 1.21225317 |
55 | MP0005332_abnormal_amino_acid | 1.18963913 |
56 | MP0002733_abnormal_thermal_nociception | 1.18911465 |
57 | MP0001502_abnormal_circadian_rhythm | 1.18831075 |
58 | MP0001970_abnormal_pain_threshold | 1.17751868 |
59 | MP0002736_abnormal_nociception_after | 1.17225922 |
60 | MP0000604_amyloidosis | 1.16582773 |
61 | MP0008874_decreased_physiological_sensi | 1.15551768 |
62 | MP0004811_abnormal_neuron_physiology | 1.13833496 |
63 | MP0002557_abnormal_social/conspecific_i | 1.13409510 |
64 | MP0000747_muscle_weakness | 1.12025607 |
65 | MP0002118_abnormal_lipid_homeostasis | 1.11367749 |
66 | MP0003123_paternal_imprinting | 1.10769633 |
67 | MP0002066_abnormal_motor_capabilities/c | 1.09021353 |
68 | MP0010234_abnormal_vibrissa_follicle | 1.08278013 |
69 | MP0003631_nervous_system_phenotype | 1.07375117 |
70 | MP0000759_abnormal_skeletal_muscle | 1.07056370 |
71 | MP0008872_abnormal_physiological_respon | 1.04104538 |
72 | MP0000566_synostosis | 1.03975040 |
73 | MP0003195_calcinosis | 1.01628829 |
74 | MP0005620_abnormal_muscle_contractility | 0.99441061 |
75 | MP0002735_abnormal_chemical_nociception | 0.99083232 |
76 | MP0000749_muscle_degeneration | 0.98861035 |
77 | MP0004085_abnormal_heartbeat | 0.98211977 |
78 | MP0000955_abnormal_spinal_cord | 0.98108056 |
79 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.97057729 |
80 | MP0005551_abnormal_eye_electrophysiolog | 0.96132410 |
81 | MP0002184_abnormal_innervation | 0.95408187 |
82 | MP0001348_abnormal_lacrimal_gland | 0.95011940 |
83 | MP0001177_atelectasis | 0.94319598 |
84 | MP0005670_abnormal_white_adipose | 0.93257907 |
85 | MP0002069_abnormal_eating/drinking_beha | 0.89812929 |
86 | MP0002882_abnormal_neuron_morphology | 0.89431987 |
87 | MP0003632_abnormal_nervous_system | 0.88021690 |
88 | MP0005083_abnormal_biliary_tract | 0.87744286 |
89 | MP0004510_myositis | 0.87605519 |
90 | MP0002269_muscular_atrophy | 0.87456981 |
91 | MP0002249_abnormal_larynx_morphology | 0.87148812 |
92 | MP0002106_abnormal_muscle_physiology | 0.86667223 |
93 | MP0004087_abnormal_muscle_fiber | 0.86452604 |
94 | MP0005666_abnormal_adipose_tissue | 0.85503295 |
95 | MP0003137_abnormal_impulse_conducting | 0.85164924 |
96 | MP0005375_adipose_tissue_phenotype | 0.84154494 |
97 | MP0000579_abnormal_nail_morphology | 0.82489637 |
98 | MP0002229_neurodegeneration | 0.81782760 |
99 | MP0003191_abnormal_cellular_cholesterol | 0.81181561 |
100 | MP0001346_abnormal_lacrimal_gland | 0.80994842 |
101 | MP0005369_muscle_phenotype | 0.79455121 |
102 | MP0000920_abnormal_myelination | 0.78449130 |
103 | MP0001963_abnormal_hearing_physiology | 0.77131915 |
104 | MP0005623_abnormal_meninges_morphology | 0.77023230 |
105 | MP0000778_abnormal_nervous_system | 0.76435968 |
106 | MP0001666_abnormal_nutrient_absorption | 0.76411700 |
107 | MP0001299_abnormal_eye_distance/ | 0.76213174 |
108 | MP0002971_abnormal_brown_adipose | 0.76098174 |
109 | MP0004084_abnormal_cardiac_muscle | 0.75699433 |
110 | MP0004233_abnormal_muscle_weight | 0.75636176 |
111 | MP0003787_abnormal_imprinting | 0.75294026 |
112 | MP0009840_abnormal_foam_cell | 0.75201562 |
113 | MP0001765_abnormal_ion_homeostasis | 0.75073019 |
114 | MP0003705_abnormal_hypodermis_morpholog | 0.75009952 |
115 | MP0002152_abnormal_brain_morphology | 0.74817648 |
116 | MP0003283_abnormal_digestive_organ | 0.74717342 |
117 | MP0004142_abnormal_muscle_tone | 0.73964145 |
118 | MP0002078_abnormal_glucose_homeostasis | 0.73819726 |
119 | MP0005330_cardiomyopathy | 0.73592502 |
120 | MP0006276_abnormal_autonomic_nervous | 0.73064923 |
121 | MP0005166_decreased_susceptibility_to | 0.70546026 |
122 | MP0002876_abnormal_thyroid_physiology | 0.70375147 |
123 | MP0001958_emphysema | 0.68340135 |
124 | MP0004742_abnormal_vestibular_system | 0.67923505 |
125 | MP0003045_fibrosis | 0.67420500 |
126 | MP0001485_abnormal_pinna_reflex | 0.67145321 |
127 | MP0000003_abnormal_adipose_tissue | 0.66685444 |
128 | MP0002332_abnormal_exercise_endurance | 0.65419051 |
129 | MP0006138_congestive_heart_failure | 0.65418750 |
130 | MP0002089_abnormal_postnatal_growth/wei | 0.63926698 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Myokymia (HP:0002411) | 5.41003781 |
2 | Focal motor seizures (HP:0011153) | 5.21791524 |
3 | Obstructive sleep apnea (HP:0002870) | 4.08943017 |
4 | Focal seizures (HP:0007359) | 4.03235270 |
5 | Visual hallucinations (HP:0002367) | 3.65185793 |
6 | Abnormality of binocular vision (HP:0011514) | 3.61045644 |
7 | Diplopia (HP:0000651) | 3.61045644 |
8 | Action tremor (HP:0002345) | 3.58500494 |
9 | Exercise-induced myalgia (HP:0003738) | 3.50244845 |
10 | Muscle fiber inclusion bodies (HP:0100299) | 3.27982382 |
11 | Type 1 muscle fiber predominance (HP:0003803) | 3.23898777 |
12 | Nemaline bodies (HP:0003798) | 3.19858980 |
13 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 3.11002188 |
14 | Generalized tonic-clonic seizures (HP:0002069) | 2.95894585 |
15 | Dysdiadochokinesis (HP:0002075) | 2.91847754 |
16 | Abnormal social behavior (HP:0012433) | 2.86249380 |
17 | Impaired social interactions (HP:0000735) | 2.86249380 |
18 | Deep venous thrombosis (HP:0002625) | 2.85664002 |
19 | Dysmetric saccades (HP:0000641) | 2.83654278 |
20 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.81190731 |
21 | Abnormality of the lower motor neuron (HP:0002366) | 2.79407989 |
22 | Poor eye contact (HP:0000817) | 2.78086581 |
23 | Epileptic encephalopathy (HP:0200134) | 2.75712486 |
24 | Postural instability (HP:0002172) | 2.75512375 |
25 | Muscle fiber splitting (HP:0003555) | 2.74016441 |
26 | Torticollis (HP:0000473) | 2.73930364 |
27 | Depression (HP:0000716) | 2.73059874 |
28 | Papilledema (HP:0001085) | 2.70389698 |
29 | Absence seizures (HP:0002121) | 2.69932191 |
30 | Intention tremor (HP:0002080) | 2.69904750 |
31 | Status epilepticus (HP:0002133) | 2.68427742 |
32 | Progressive cerebellar ataxia (HP:0002073) | 2.61860927 |
33 | Bundle branch block (HP:0011710) | 2.61575439 |
34 | Anxiety (HP:0000739) | 2.60870847 |
35 | Ketosis (HP:0001946) | 2.59046154 |
36 | Atonic seizures (HP:0010819) | 2.57589054 |
37 | Febrile seizures (HP:0002373) | 2.55351926 |
38 | Dysmetria (HP:0001310) | 2.55125961 |
39 | Ankle clonus (HP:0011448) | 2.53381341 |
40 | Supranuclear gaze palsy (HP:0000605) | 2.53064799 |
41 | Ventricular fibrillation (HP:0001663) | 2.51214402 |
42 | Ketoacidosis (HP:0001993) | 2.49403890 |
43 | Focal dystonia (HP:0004373) | 2.46471216 |
44 | Neuronal loss in central nervous system (HP:0002529) | 2.46045748 |
45 | Xanthomatosis (HP:0000991) | 2.44688874 |
46 | Difficulty running (HP:0009046) | 2.43663230 |
47 | Myoglobinuria (HP:0002913) | 2.43273880 |
48 | Myopathic facies (HP:0002058) | 2.42650677 |
49 | Dialeptic seizures (HP:0011146) | 2.42499623 |
50 | Gaze-evoked nystagmus (HP:0000640) | 2.41964766 |
51 | Gout (HP:0001997) | 2.41653289 |
52 | Scanning speech (HP:0002168) | 2.40745651 |
53 | Neurofibrillary tangles (HP:0002185) | 2.40378861 |
54 | Resting tremor (HP:0002322) | 2.38536486 |
55 | Sudden death (HP:0001699) | 2.38427448 |
56 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.37711864 |
57 | Rapidly progressive (HP:0003678) | 2.35184240 |
58 | Craniofacial dystonia (HP:0012179) | 2.35104737 |
59 | Exercise-induced muscle cramps (HP:0003710) | 2.34962749 |
60 | Hemiplegia (HP:0002301) | 2.34566768 |
61 | Hyperventilation (HP:0002883) | 2.33486147 |
62 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.33034912 |
63 | Urinary urgency (HP:0000012) | 2.32536802 |
64 | Broad-based gait (HP:0002136) | 2.32335824 |
65 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.32195669 |
66 | EMG: myopathic abnormalities (HP:0003458) | 2.31297858 |
67 | Hyperlipoproteinemia (HP:0010980) | 2.30025812 |
68 | Mutism (HP:0002300) | 2.30018117 |
69 | Cerebral inclusion bodies (HP:0100314) | 2.29907609 |
70 | Sleep apnea (HP:0010535) | 2.27687565 |
71 | Akinesia (HP:0002304) | 2.27548065 |
72 | Rigidity (HP:0002063) | 2.25610336 |
73 | Distal lower limb muscle weakness (HP:0009053) | 2.24928072 |
74 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.23545453 |
75 | Aplasia of the phalanges of the hand (HP:0009802) | 2.23545453 |
76 | Aplasia involving bones of the extremities (HP:0009825) | 2.23545453 |
77 | Foot dorsiflexor weakness (HP:0009027) | 2.21028203 |
78 | Insomnia (HP:0100785) | 2.19095361 |
79 | Abnormal eating behavior (HP:0100738) | 2.16054253 |
80 | Atrioventricular block (HP:0001678) | 2.15540641 |
81 | Heart block (HP:0012722) | 2.15339912 |
82 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.14391980 |
83 | Complement deficiency (HP:0004431) | 2.09609705 |
84 | Prolonged QT interval (HP:0001657) | 2.08989245 |
85 | Hyporeflexia of lower limbs (HP:0002600) | 2.08794454 |
86 | Clonus (HP:0002169) | 2.08127609 |
87 | Impaired vibratory sensation (HP:0002495) | 2.07780075 |
88 | Abnormality of the Achilles tendon (HP:0005109) | 2.07416204 |
89 | Turricephaly (HP:0000262) | 2.07036570 |
90 | Abnormality of the foot musculature (HP:0001436) | 2.06289892 |
91 | Cerebral hypomyelination (HP:0006808) | 2.05790910 |
92 | Round ear (HP:0100830) | 2.05306945 |
93 | Muscle stiffness (HP:0003552) | 2.04704348 |
94 | Hypoalphalipoproteinemia (HP:0003233) | 2.03899325 |
95 | Fetal akinesia sequence (HP:0001989) | 2.03597491 |
96 | Intrahepatic cholestasis (HP:0001406) | 2.03081684 |
97 | Hyperglycinuria (HP:0003108) | 2.01802578 |
98 | Hyperammonemia (HP:0001987) | 2.01311157 |
99 | Increased variability in muscle fiber diameter (HP:0003557) | 2.01005975 |
100 | Truncal ataxia (HP:0002078) | 2.00944359 |
101 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.99669132 |
102 | Abnormality of glycine metabolism (HP:0010895) | 1.99669132 |
103 | EMG: neuropathic changes (HP:0003445) | 1.99028037 |
104 | Calf muscle hypertrophy (HP:0008981) | 1.98475187 |
105 | Delayed CNS myelination (HP:0002188) | 1.98148420 |
106 | Annular pancreas (HP:0001734) | 1.97931233 |
107 | Bronchomalacia (HP:0002780) | 1.97409997 |
108 | Abnormal atrioventricular conduction (HP:0005150) | 1.97138732 |
109 | Muscle hypertrophy of the lower extremities (HP:0008968) | 1.97048383 |
110 | Increased connective tissue (HP:0009025) | 1.96057179 |
111 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.93359777 |
112 | Increased circulating renin level (HP:0000848) | 1.93201578 |
113 | Spastic gait (HP:0002064) | 1.92829666 |
114 | Apathy (HP:0000741) | 1.92800077 |
115 | Stridor (HP:0010307) | 1.92040191 |
116 | Upper limb amyotrophy (HP:0009129) | 1.91370545 |
117 | Distal upper limb amyotrophy (HP:0007149) | 1.91370545 |
118 | Syncope (HP:0001279) | 1.91051867 |
119 | Hyperglycinemia (HP:0002154) | 1.89342994 |
120 | Frequent falls (HP:0002359) | 1.88412128 |
121 | Bradykinesia (HP:0002067) | 1.88182141 |
122 | Achilles tendon contracture (HP:0001771) | 1.87230016 |
123 | Lower limb asymmetry (HP:0100559) | 1.86603254 |
124 | Tetraplegia (HP:0002445) | 1.86385162 |
125 | Abnormal EKG (HP:0003115) | 1.85590066 |
126 | Hypercortisolism (HP:0001578) | 1.84927813 |
127 | Lower limb amyotrophy (HP:0007210) | 1.84872458 |
128 | Peripheral hypomyelination (HP:0007182) | 1.84000490 |
129 | Cerebral aneurysm (HP:0004944) | 1.83722368 |
130 | Hemiparesis (HP:0001269) | 1.83029888 |
131 | Myotonia (HP:0002486) | 1.82721251 |
132 | Slow progression (HP:0003677) | 1.81663215 |
133 | Impaired smooth pursuit (HP:0007772) | 1.81472695 |
134 | Neonatal onset (HP:0003623) | 1.81106371 |
135 | Abnormal gallbladder physiology (HP:0012438) | 1.80152678 |
136 | Cholecystitis (HP:0001082) | 1.80152678 |
137 | Lower limb muscle weakness (HP:0007340) | 1.79973321 |
138 | Central scotoma (HP:0000603) | 1.79812201 |
139 | Ventricular arrhythmia (HP:0004308) | 1.79204024 |
140 | Hyperkalemia (HP:0002153) | 1.76894545 |
141 | Amblyopia (HP:0000646) | 1.76395989 |
142 | Genetic anticipation (HP:0003743) | 1.73871356 |
143 | Megalencephaly (HP:0001355) | 1.73530229 |
144 | Cholelithiasis (HP:0001081) | 1.73368236 |
145 | Abnormality of the periventricular white matter (HP:0002518) | 1.72754898 |
146 | Termporal pattern (HP:0011008) | 1.72443241 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA4 | 4.55651997 |
2 | NTRK3 | 3.77615367 |
3 | MAP3K9 | 3.01076987 |
4 | DAPK2 | 2.78674280 |
5 | KSR2 | 2.37799140 |
6 | PRKD3 | 2.24955359 |
7 | MAP3K4 | 2.24944751 |
8 | PAK6 | 2.01466648 |
9 | MAP2K4 | 1.96767211 |
10 | CAMKK1 | 1.93573842 |
11 | TRIB3 | 1.79993685 |
12 | MINK1 | 1.79710391 |
13 | RIPK1 | 1.70267643 |
14 | PINK1 | 1.67438981 |
15 | STK38 | 1.67266838 |
16 | PHKG2 | 1.65011318 |
17 | PHKG1 | 1.65011318 |
18 | NTRK1 | 1.64303990 |
19 | NTRK2 | 1.56578886 |
20 | MAP3K2 | 1.56560944 |
21 | TYRO3 | 1.38810205 |
22 | PRPF4B | 1.38633377 |
23 | LMTK2 | 1.35835468 |
24 | MARK1 | 1.30326104 |
25 | MAP3K13 | 1.28158508 |
26 | RIPK4 | 1.27846120 |
27 | CDK5 | 1.27053359 |
28 | KSR1 | 1.25975784 |
29 | MAP2K7 | 1.25137555 |
30 | EEF2K | 1.19459562 |
31 | MAP3K7 | 1.16334632 |
32 | PRKCH | 1.14095505 |
33 | SGK494 | 1.13966716 |
34 | SGK223 | 1.13966716 |
35 | SGK3 | 1.13018718 |
36 | TAOK1 | 1.12025665 |
37 | RET | 1.03170899 |
38 | SIK2 | 1.02505061 |
39 | DAPK1 | 1.02365636 |
40 | SGK2 | 0.98941703 |
41 | CAMKK2 | 0.98458700 |
42 | CAMK1G | 0.97928025 |
43 | PDPK1 | 0.97436470 |
44 | PKN2 | 0.97200515 |
45 | SIK1 | 0.95919660 |
46 | TTN | 0.95904569 |
47 | BCKDK | 0.95682371 |
48 | FES | 0.94817689 |
49 | NEK1 | 0.94214928 |
50 | NEK6 | 0.92893763 |
51 | OXSR1 | 0.91522812 |
52 | PRKCG | 0.89552232 |
53 | TESK1 | 0.89214619 |
54 | STK11 | 0.87140818 |
55 | PDK1 | 0.87006287 |
56 | PTK2B | 0.86778859 |
57 | CAMK1 | 0.86219508 |
58 | FGFR2 | 0.85754898 |
59 | PAK3 | 0.85639679 |
60 | ARAF | 0.85119304 |
61 | CASK | 0.82664008 |
62 | CDK19 | 0.82220332 |
63 | WNK1 | 0.81287856 |
64 | PDK3 | 0.78457513 |
65 | PDK4 | 0.78457513 |
66 | DMPK | 0.77263730 |
67 | SGK1 | 0.76699372 |
68 | WNK4 | 0.75581399 |
69 | TNIK | 0.75402757 |
70 | PDGFRA | 0.74490146 |
71 | OBSCN | 0.74114958 |
72 | MAP3K1 | 0.73696683 |
73 | CDK11A | 0.73410087 |
74 | GRK5 | 0.73215019 |
75 | MAPK10 | 0.73091516 |
76 | INSRR | 0.72542711 |
77 | CAMK2A | 0.72273438 |
78 | MAP3K11 | 0.72118413 |
79 | DYRK1A | 0.70583293 |
80 | LIMK1 | 0.68330901 |
81 | PLK2 | 0.67581963 |
82 | MARK2 | 0.67409087 |
83 | CAMK1D | 0.66566223 |
84 | MAP2K1 | 0.65574605 |
85 | CAMK4 | 0.63707036 |
86 | DAPK3 | 0.61082412 |
87 | CAMK2G | 0.60532705 |
88 | FER | 0.60078589 |
89 | MAPK12 | 0.59218486 |
90 | MOS | 0.58752194 |
91 | ROCK2 | 0.58207132 |
92 | RAF1 | 0.57835476 |
93 | PRKCZ | 0.57485827 |
94 | BRAF | 0.56419714 |
95 | RPS6KA3 | 0.56384969 |
96 | CAMK2B | 0.54722639 |
97 | CDC42BPA | 0.54122769 |
98 | TNK2 | 0.53238617 |
99 | DDR2 | 0.52424703 |
100 | UHMK1 | 0.52079901 |
101 | MAPK7 | 0.51404637 |
102 | PKN1 | 0.51065553 |
103 | PRKD1 | 0.50641677 |
104 | ALK | 0.50553469 |
105 | FGFR4 | 0.50522749 |
106 | CDK15 | 0.50197413 |
107 | LATS2 | 0.48749862 |
108 | CAMK2D | 0.48387835 |
109 | RPS6KA2 | 0.47906672 |
110 | CDK18 | 0.46682696 |
111 | BMX | 0.45842684 |
112 | SMG1 | 0.45437473 |
113 | ERN1 | 0.45426441 |
114 | ICK | 0.45126612 |
115 | PRKG2 | 0.45092351 |
116 | PRKAA1 | 0.44933691 |
117 | MAP2K6 | 0.44845111 |
118 | MAPK4 | 0.44550503 |
119 | ROCK1 | 0.44374604 |
120 | CDK14 | 0.43134217 |
121 | DYRK1B | 0.42905582 |
122 | TAOK2 | 0.41935476 |
123 | PRKACG | 0.41665417 |
124 | MAPK13 | 0.41475292 |
125 | PDK2 | 0.41392416 |
126 | PRKD2 | 0.40812178 |
127 | FYN | 0.40406794 |
128 | PTK2 | 0.40394694 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.55739315 |
2 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.34493976 |
3 | Nicotine addiction_Homo sapiens_hsa05033 | 2.04781095 |
4 | Olfactory transduction_Homo sapiens_hsa04740 | 1.98794232 |
5 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.97665993 |
6 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.95709450 |
7 | GABAergic synapse_Homo sapiens_hsa04727 | 1.91209280 |
8 | Circadian entrainment_Homo sapiens_hsa04713 | 1.88918166 |
9 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.87402919 |
10 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.82495977 |
11 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.74752641 |
12 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.66131837 |
13 | Long-term potentiation_Homo sapiens_hsa04720 | 1.65880147 |
14 | Morphine addiction_Homo sapiens_hsa05032 | 1.64457972 |
15 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.58788689 |
16 | Salivary secretion_Homo sapiens_hsa04970 | 1.57368231 |
17 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.54471613 |
18 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.50886871 |
19 | Bile secretion_Homo sapiens_hsa04976 | 1.50662139 |
20 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.45847988 |
21 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.44639834 |
22 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.42675663 |
23 | Insulin secretion_Homo sapiens_hsa04911 | 1.41861292 |
24 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.35388847 |
25 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.33575676 |
26 | Renin secretion_Homo sapiens_hsa04924 | 1.32231281 |
27 | Histidine metabolism_Homo sapiens_hsa00340 | 1.31971435 |
28 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.30967209 |
29 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.30735814 |
30 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.28700106 |
31 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.27648341 |
32 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.26373728 |
33 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.26238481 |
34 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.23500110 |
35 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.19141085 |
36 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.16027353 |
37 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.15823444 |
38 | Cocaine addiction_Homo sapiens_hsa05030 | 1.14523961 |
39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.14032160 |
40 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.13755607 |
41 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.10198185 |
42 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.07813569 |
43 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.07012333 |
44 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.06431724 |
45 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.05945049 |
46 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.02826294 |
47 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.01465873 |
48 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.95918490 |
49 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.95346329 |
50 | Long-term depression_Homo sapiens_hsa04730 | 0.95165167 |
51 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.94028974 |
52 | Taste transduction_Homo sapiens_hsa04742 | 0.93984372 |
53 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.85716192 |
54 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.84917892 |
55 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.84681481 |
56 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.82849106 |
57 | Gap junction_Homo sapiens_hsa04540 | 0.82123648 |
58 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.81572336 |
59 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.80756589 |
60 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.79628787 |
61 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.76933535 |
62 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.76498890 |
63 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.75912191 |
64 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.75622683 |
65 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.75526260 |
66 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.74385989 |
67 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.73595215 |
68 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.72740387 |
69 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.72729933 |
70 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.70689482 |
71 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.70032034 |
72 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.68962934 |
73 | Glioma_Homo sapiens_hsa05214 | 0.68041144 |
74 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.67283464 |
75 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.66336724 |
76 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.66223167 |
77 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.65608777 |
78 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.64421512 |
79 | Carbon metabolism_Homo sapiens_hsa01200 | 0.63922651 |
80 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.62866143 |
81 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.62706247 |
82 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.62688944 |
83 | Circadian rhythm_Homo sapiens_hsa04710 | 0.62349127 |
84 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.62127722 |
85 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.61502462 |
86 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.60261935 |
87 | Peroxisome_Homo sapiens_hsa04146 | 0.58084640 |
88 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.56963891 |
89 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.56722118 |
90 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.56440403 |
91 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.55957378 |
92 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.55786999 |
93 | Melanogenesis_Homo sapiens_hsa04916 | 0.55441444 |
94 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.54918900 |
95 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.54670342 |
96 | Insulin resistance_Homo sapiens_hsa04931 | 0.53687461 |
97 | ABC transporters_Homo sapiens_hsa02010 | 0.51962620 |
98 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.51870466 |
99 | Tight junction_Homo sapiens_hsa04530 | 0.51606426 |
100 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.50295410 |
101 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.49619406 |
102 | Endocytosis_Homo sapiens_hsa04144 | 0.48630150 |
103 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.47942082 |
104 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.47857012 |
105 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.47395021 |
106 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.47257331 |
107 | Prion diseases_Homo sapiens_hsa05020 | 0.46708880 |
108 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.46448585 |
109 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.45892944 |
110 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.45802539 |
111 | Mineral absorption_Homo sapiens_hsa04978 | 0.45777855 |
112 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.44319058 |
113 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.43172268 |
114 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.43165528 |
115 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.42387799 |
116 | Axon guidance_Homo sapiens_hsa04360 | 0.40740092 |
117 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.40644917 |
118 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.40388718 |
119 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.40152223 |
120 | Endometrial cancer_Homo sapiens_hsa05213 | 0.36291529 |
121 | Focal adhesion_Homo sapiens_hsa04510 | 0.34197988 |
122 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.33687254 |
123 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.33649407 |
124 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.33095759 |